Detailed information for compound 953355

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 530.605 | Formula: C26H42O11
  • H donors: 0 H acceptors: 5 LogP: 3.87 Rotable bonds: 21
    Rule of 5 violations (Lipinski): 2
  • SMILES: CCCC(=O)OC[C@H]1OC(OC(=O)CCC)[C@H]([C@H]([C@@H]1OC(=O)CCC)OC(=O)CCC)OC(=O)CCC
  • InChi: 1S/C26H42O11/c1-6-11-18(27)32-16-17-23(34-19(28)12-7-2)24(35-20(29)13-8-3)25(36-21(30)14-9-4)26(33-17)37-22(31)15-10-5/h17,23-26H,6-16H2,1-5H3/t17-,23-,24+,25+,26?/m1/s1
  • InChiKey: URBLVNWOCAGFPV-MWKUUBLRSA-N  


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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0254 0.0038 0.0051
Echinococcus granulosus protein kinase C gamma type 0.0535 0.039 0.0672
Echinococcus multilocularis 0.0862 0.0798 0.0798
Loa Loa (eye worm) hypothetical protein 0.1326 0.1379 0.1859
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0612 0.0486 0.1194
Leishmania major protein kinase A catalytic subunit isoform 2 0.0669 0.0558 0.0961
Brugia malayi ephrin receptor 1 precursor 0.0254 0.0037 0.0051
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0545 0.0402 0.0402
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0989 0.0957 0.0957
Schistosoma mansoni protein kinase 0.2258 0.2546 0.6256
Trichomonas vaginalis STE family protein kinase 0.1111 0.111 1
Schistosoma mansoni serine/threonine protein kinase 0.0675 0.0565 0.1389
Echinococcus multilocularis protein kinase c epsilon type 0.0636 0.0516 0.0516
Echinococcus multilocularis fibroblast growth factor receptor 4 0.1306 0.1354 0.1354
Echinococcus granulosus STE20 serine:threonine protein kinase 0.0606 0.0478 0.0824
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.1811 0.1986 0.3423
Schistosoma mansoni serine/threonine protein kinase 0.0608 0.0481 0.1181
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0989 0.0957 0.0957
Schistosoma mansoni serine/threonine protein kinase 0.0249 0.0031 0.0077
Schistosoma mansoni protein kinase 0.0545 0.0402 0.0988
Brugia malayi Protein kinase domain containing protein 0.0314 0.0114 0.0153
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0271 0.0059 0.0059
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0989 0.0957 0.0957
Loa Loa (eye worm) TK protein kinase 0.0525 0.0377 0.0508
Trichomonas vaginalis CAMK family protein kinase 0.0229 0.0007 0.0065
Loa Loa (eye worm) hypothetical protein 0.0254 0.0038 0.0051
Echinococcus granulosus tyrosine protein kinase otk 0.0254 0.0038 0.0065
Onchocerca volvulus Slit protein homolog 0.0246 0.0028 0.0038
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.1247 0.128 0.128
Plasmodium falciparum serine/threonine protein kinase KIN 0.0316 0.0116 0.1119
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0341 0.0147 0.0147
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.034 0.0146 0.0252
Echinococcus multilocularis cyclin dependent kinase 19 0.158 0.1697 0.1697
Echinococcus multilocularis mitogen activated protein kinase 14 0.4862 0.5804 0.5804
Entamoeba histolytica leucine-rich repeat domain-containing protein 0.0226 0.0003 0.0033
Echinococcus multilocularis serine:threonine protein kinase N2 0.1022 0.0999 0.0999
Echinococcus granulosus tyrosine protein kinase HCK 0.063 0.0508 0.0875
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0253 0.0037 0.0064
Trichomonas vaginalis CAMK family protein kinase 0.0309 0.0107 0.096
Schistosoma mansoni vav2 0.0382 0.0198 0.0486
Schistosoma mansoni rap gtpase-activating protein 0.0612 0.0486 0.1194
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0725 0.0628 0.1081
Entamoeba histolytica protein kinase, putative 0.0617 0.0492 0.4757
Schistosoma mansoni nck2/grb4 0.0359 0.017 0.0417
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0612 0.0486 0.1194
Trichomonas vaginalis AGC family protein kinase 0.0658 0.0544 0.4897
Loa Loa (eye worm) hypothetical protein 0.0612 0.0486 0.0655
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0948 0.0906 0.1562
Brugia malayi Protein kinase domain containing protein 0.0278 0.0068 0.0092
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0351 0.016 0.0215
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0501 0.0347 0.3352
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.0309 0.0107 0.0144
Echinococcus multilocularis activated cdc42 kinase 1 0.1544 0.1652 0.1652
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.047 0.0309 0.0309
Echinococcus multilocularis tyrosine protein kinase shark 0.0636 0.0516 0.0516
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0359 0.017 0.0229
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0396 0.0215 0.0371
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0275 0.0065 0.0087
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.0316 0.0116 0.02
Brugia malayi casein kinase 1, delta 0.0561 0.0422 0.057
Schistosoma mansoni tyrosine kinase 0.3476 0.407 1
Brugia malayi Immunoglobulin I-set domain containing protein 0.0254 0.0038 0.0051
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0928 0.0882 0.152
Echinococcus granulosus insulin receptor 0.1232 0.1261 0.2174
Echinococcus multilocularis mitogen activated protein kinase 11 0.4862 0.5804 0.5804
Schistosoma mansoni serine/threonine protein kinase 0.0327 0.0129 0.0317
Onchocerca volvulus 0.07 0.0597 0.0805
Loa Loa (eye worm) hypothetical protein 0.07 0.0597 0.0805
Brugia malayi Protein kinase domain containing protein 0.0309 0.0107 0.0144
Echinococcus multilocularis roundabout 2 0.0838 0.0769 0.0769
Trichomonas vaginalis STE family protein kinase 0.1111 0.111 1
Plasmodium falciparum NIMA related kinase 1 0.025 0.0033 0.0323
Brugia malayi serine/threonine-protein kinase 6 0.0545 0.0402 0.0542
Echinococcus granulosus casein kinase I delta 0.0561 0.0422 0.0728
Echinococcus multilocularis casein kinase I delta 0.0561 0.0422 0.0422
Loa Loa (eye worm) hypothetical protein 0.0807 0.073 0.0985
Schistosoma mansoni serine/threonine protein kinase 0.2568 0.2934 0.7209
Entamoeba histolytica protein kinase, putative 0.0501 0.0347 0.3352
Loa Loa (eye worm) hypothetical protein 0.0508 0.0356 0.048
Trichomonas vaginalis CMGC family protein kinase 0.1051 0.1035 0.9324
Schistosoma mansoni ste20-related kinase 0.0319 0.0119 0.0292
Echinococcus granulosus roundabout 2 0.0838 0.0769 0.1325
Trypanosoma brucei casein kinase I, isoform 2 0.0561 0.0422 0.0728
Trichomonas vaginalis CAMK family protein kinase 0.0321 0.0122 0.1103
Schistosoma mansoni serine/threonine protein kinase 0.0891 0.0835 0.2052
Trichomonas vaginalis STE family protein kinase 0.025 0.0033 0.0301
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.0612 0.0486 0.0837
Echinococcus granulosus roundabout 2 0.0285 0.0077 0.0133
Brugia malayi Immunoglobulin I-set domain containing protein 0.3111 0.3612 0.4871
Brugia malayi Variant SH3 domain containing protein 0.0359 0.017 0.0229
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0561 0.0422 0.057
Schistosoma mansoni serine/threonine protein kinase 0.0249 0.0031 0.0077
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.0253 0.0037 0.0064
Loa Loa (eye worm) CMGC/GSK protein kinase 0.1051 0.1035 0.1396
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0316 0.0116 0.0116
Echinococcus granulosus serine threonine protein kinase nrc 0.0271 0.0059 0.0101
Schistosoma mansoni serine/threonine protein kinase 0.0309 0.0108 0.0264
Echinococcus multilocularis twitchin 0.032 0.012 0.012
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0553 0.0412 0.1014
Onchocerca volvulus 0.0424 0.0251 0.0338
Trichomonas vaginalis CK1 family protein kinase 0.0561 0.0422 0.3804
Brugia malayi Peroxidasin 0.0257 0.0041 0.0056
Echinococcus granulosus protein kinase 0.0862 0.0798 0.1376
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.2086 0.233 0.3142
Echinococcus multilocularis homeodomain interacting protein kinase 3 0.0316 0.0116 0.0116
Trypanosoma brucei cdc2-related kinase 3 0.0404 0.0226 0.0389
Loa Loa (eye worm) hypothetical protein 0.0424 0.0251 0.0338
Entamoeba histolytica protein kinase, putative 0.0348 0.0156 0.151
Echinococcus granulosus casein kinase I alpha 0.0561 0.0422 0.0728
Brugia malayi Protein kinase domain containing protein 0.0406 0.0228 0.0308
Trichomonas vaginalis CAMK family protein kinase 0.0316 0.0116 0.1043
Schistosoma mansoni hypothetical protein 0.0612 0.0486 0.1194
Echinococcus multilocularis PAK box P21 Rho binding 0.0319 0.0119 0.0119
Schistosoma mansoni protein kinase 0.0306 0.0104 0.0255
Schistosoma mansoni titin 0.0351 0.016 0.0392
Schistosoma mansoni tyrosine kinase 0.1873 0.2063 0.507
Echinococcus granulosus c-Jun N-terminal kinases 0.2666 0.3056 0.5266
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0316 0.0116 0.02
Loa Loa (eye worm) AGC/PKN protein kinase 0.1517 0.1618 0.2182
Brugia malayi Protein kinase domain containing protein 0.0424 0.0251 0.0338
Echinococcus multilocularis hemicentin 1 0.0254 0.0038 0.0038
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0413 0.0237 0.0409
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.1047 0.103 0.1389
Brugia malayi Immunoglobulin I-set domain containing protein 0.0254 0.0038 0.0051
Brugia malayi cyclin-dependent kinase 9 0.0331 0.0134 0.0181
Brugia malayi Protein kinase domain containing protein 0.3515 0.4118 0.5553
Loa Loa (eye worm) AUR protein kinase 0.0545 0.0402 0.0542
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0865 0.0802 0.1082
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0928 0.0882 0.1189
Loa Loa (eye worm) hypothetical protein 0.0502 0.0348 0.0469
Brugia malayi Serine/threonine-protein kinase Pim-3 0.2046 0.228 0.3075
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0501 0.0347 0.0598
Loa Loa (eye worm) hypothetical protein 0.0781 0.0697 0.094
Loa Loa (eye worm) AGC/PKG protein kinase 0.0249 0.0031 0.0042
Giardia lamblia Kinase, STE STE20 0.1111 0.111 1
Echinococcus multilocularis dual specificity 0.0253 0.0037 0.0037
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.1047 0.103 0.1774
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0501 0.0347 0.0598
Brugia malayi Protein kinase domain containing protein 0.0404 0.0226 0.0304
Echinococcus multilocularis casein kinase I gamma 0.0327 0.0129 0.0129
Brugia malayi Protein kinase domain containing protein 0.1544 0.1652 0.2227
Brugia malayi Fibronectin type III domain containing protein 0.0584 0.0452 0.0609
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0989 0.0957 0.165
Echinococcus granulosus peroxidasin 0.0257 0.0041 0.0071
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0941 0.0898 0.1547
Giardia lamblia Kinase, CMGC CDK 0.0404 0.0226 0.2034
Schistosoma mansoni atypical protein kinase C 0.0723 0.0625 0.1535
Giardia lamblia Kinase, NEK 0.025 0.0033 0.0301
Echinococcus granulosus fibroblast growth factor receptor 4 0.1306 0.1354 0.2333
Loa Loa (eye worm) hypothetical protein 0.0246 0.0028 0.0038
Plasmodium vivax casein kinase 1, putative 0.0561 0.0422 0.408
Brugia malayi casein kinase I 0.0561 0.0422 0.057
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0271 0.0059 0.0101
Trichomonas vaginalis CMGC family protein kinase 0.0253 0.0037 0.0332
Toxoplasma gondii AGC kinase 0.0669 0.0558 0.539
Trichomonas vaginalis CAMK family protein kinase 0.0501 0.0347 0.3125
Brugia malayi Protein kinase domain containing protein 0.0494 0.0339 0.0457
Echinococcus granulosus activated cdc42 kinase 1 0.1544 0.1652 0.2846
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0404 0.0226 0.2181
Schistosoma mansoni protein kinase 0.034 0.0146 0.0359
Echinococcus multilocularis aurora kinase A 0.0545 0.0402 0.0402
Loa Loa (eye worm) TK/FER protein kinase 0.0424 0.0251 0.0338
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.034 0.0146 0.0252
Echinococcus granulosus dual specificity mitogen activated protein 0.1111 0.111 0.1913
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0545 0.0402 0.3885
Plasmodium falciparum protein kinase, putative 0.0371 0.0185 0.1788
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0891 0.0835 0.1439
Echinococcus granulosus neuroglian 0.0725 0.0628 0.1082
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0404 0.0226 0.0389
Onchocerca volvulus 0.0689 0.0582 0.0785
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.1946 0.2155 0.2906
Brugia malayi Immunoglobulin I-set domain containing protein 0.0285 0.0077 0.0104
Echinococcus granulosus epidermal growth factor receptor 0.0932 0.0886 0.1526
Loa Loa (eye worm) CAMK/PIM protein kinase 0.2046 0.228 0.3075
Giardia lamblia Aurora kinase 0.0545 0.0402 0.3623
Trichomonas vaginalis CMGC family protein kinase 0.1051 0.1035 0.9324
Echinococcus granulosus phosphorylase kinase gamma subunit 0.0278 0.0068 0.0117
Loa Loa (eye worm) TK/EPH protein kinase 0.0304 0.0101 0.0137
Brugia malayi Furin-like cysteine rich region family protein 0.0932 0.0886 0.1194
Schistosoma mansoni serine/threonine protein kinase 0.1474 0.1564 0.3844
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.2046 0.228 0.3929
Entamoeba histolytica protein kinase, putative 0.1047 0.103 0.9948
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.2165 0.2429 0.2429
Loa Loa (eye worm) hypothetical protein 0.1544 0.1652 0.2227
Loa Loa (eye worm) hypothetical protein 0.0612 0.0486 0.0655
Schistosoma mansoni tyrosine kinase 0.057 0.0434 0.1066
Echinococcus granulosus mitogen activated protein kinase 14 0.4862 0.5804 1
Trichomonas vaginalis AGC family protein kinase 0.0545 0.0402 0.3623
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0253 0.0037 0.0064
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0732 0.0636 0.1096
Brugia malayi hypothetical protein 0.2568 0.2934 0.3956
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0621 0.0498 0.0498
Schistosoma mansoni hypothetical protein 0.0308 0.0106 0.0261
Echinococcus multilocularis transfer RNA-Thr 0.1544 0.1652 0.1652
Schistosoma mansoni tyrosine kinase 0.0477 0.0318 0.078
Schistosoma mansoni serine/threonine protein kinase 0.158 0.1697 0.4171
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0289 0.0082 0.0142
Entamoeba histolytica protein kinase domain containing protein 0.0316 0.0116 0.112
Schistosoma mansoni tyrosine kinase 0.0395 0.0214 0.0526
Brugia malayi SRC-1 0.0989 0.0957 0.1291
Entamoeba histolytica hypothetical protein 0.0225 0.0002 0.0023
Loa Loa (eye worm) CMGC/DYRK/HIPK protein kinase 0.0316 0.0116 0.0156
Trichomonas vaginalis CAMK family protein kinase 0.0316 0.0116 0.1043
Schistosoma mansoni serine/threonine protein kinase 0.0289 0.0082 0.0202
Echinococcus granulosus serine:threonine protein kinase 0.0309 0.0107 0.0184
Loa Loa (eye worm) hypothetical protein 0.0635 0.0515 0.0694
Echinococcus granulosus Immunoglobulin 0.0553 0.0412 0.0711
Echinococcus granulosus cyclin dependent kinase 7 0.0608 0.0481 0.0828
Brugia malayi intracellular kinase 0.1051 0.1035 0.1396
Echinococcus granulosus aurora kinase A 0.0545 0.0402 0.0693
Loa Loa (eye worm) TK/FER protein kinase 0.0424 0.0251 0.0338
Echinococcus granulosus slit 2 protein 0.0246 0.0028 0.0048
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0271 0.0059 0.0568
Echinococcus multilocularis cyclin dependent kinase 7 0.0608 0.0481 0.0481
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0285 0.0077 0.0189
Schistosoma mansoni serine/threonine protein kinase 0.0948 0.0906 0.2227
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.071 0.0609 0.0821
Echinococcus multilocularis tyrosine protein kinase ABL1 0.2073 0.2314 0.2314
Echinococcus granulosus activated cdc42 kinase 1 0.1544 0.1652 0.2846
Loa Loa (eye worm) hypothetical protein 0.0254 0.0038 0.0051
Trypanosoma brucei rac serine-threonine kinase, putative 0.0658 0.0544 0.0937
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.034 0.0146 0.0146
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0928 0.0882 0.152
Trichomonas vaginalis CAMK family protein kinase 0.0316 0.0116 0.1043
Brugia malayi ribosomal protein S6 kinase alpha 3 0.09 0.0846 0.1141
Echinococcus granulosus serine:threonine protein kinase mig 15 0.1326 0.1379 0.2376
Schistosoma mansoni protein kinase 0.0862 0.0798 0.1962
Echinococcus multilocularis dual specificity 0.0253 0.0037 0.0037
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0522 0.0373 0.0643
Loa Loa (eye worm) hypothetical protein 0.0256 0.0041 0.0055
Echinococcus multilocularis cyclin dependent kinase 5 0.0404 0.0226 0.0226
Loa Loa (eye worm) hypothetical protein 0.0308 0.0106 0.0143
Echinococcus granulosus lachesin 0.0254 0.0038 0.0065
Schistosoma mansoni tyrosine kinase 0.0989 0.0957 0.2352
Schistosoma mansoni serine/threonine protein kinase 0.2666 0.3056 0.7509
Echinococcus multilocularis protein kinase c iota type 0.0717 0.0617 0.0617
Giardia lamblia Kinase, NEK 0.025 0.0033 0.0301
Trichomonas vaginalis CK1 family protein kinase 0.0561 0.0422 0.3804
Echinococcus multilocularis tyrosine protein kinase otk 0.0254 0.0038 0.0038
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0977 0.0942 0.1271
Brugia malayi Immunoglobulin I-set domain containing protein 0.1478 0.1569 0.2116
Brugia malayi Protein kinase domain containing protein 0.0424 0.0251 0.0338
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.2086 0.233 0.233
Echinococcus multilocularis calcium dependent protein kinase 0.0353 0.0162 0.0162
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0254 0.0038 0.0093
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.0253 0.0037 0.005
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.0238 0.0018 0.0032
Schistosoma mansoni tyrosine kinase 0.0932 0.0886 0.2177
Schistosoma mansoni protein kinase 0.0789 0.0708 0.1739
Schistosoma mansoni titin 0.0254 0.0038 0.0093
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0669 0.0558 0.0961
Trichomonas vaginalis CMGC family protein kinase 0.0253 0.0037 0.0332
Brugia malayi protein C17H12.11 0.0547 0.0405 0.0546
Schistosoma mansoni tyrosine kinase 0.0732 0.0636 0.1563
Schistosoma mansoni tyrosine kinase 0.0989 0.0957 0.2352
Echinococcus multilocularis growth factor receptor bound protein 2 0.0359 0.017 0.017
Brugia malayi C1-like domain containing protein 0.0977 0.0942 0.1271
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0612 0.0486 0.0837
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0285 0.0077 0.0104
Brugia malayi EGF-like domain containing protein 0.0246 0.0028 0.0038
Schistosoma mansoni cell adhesion molecule 0.0254 0.0038 0.0093
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0238 0.0018 0.0018
Onchocerca volvulus Serine\/threonine kinase homolog 0.0278 0.0068 0.0092
Echinococcus multilocularis cyclin dependent kinase 9 0.0363 0.0174 0.0174
Trypanosoma cruzi casein kinase, putative 0.0561 0.0422 0.0728
Plasmodium vivax protein kinase, putative 0.0239 0.0019 0.0181
Entamoeba histolytica protein kinase domain containing protein 0.0545 0.0402 0.3885
Trichomonas vaginalis AGC family protein kinase 0.0545 0.0402 0.3623
Entamoeba histolytica serine/threonine protein kinase, putative 0.0289 0.0082 0.0796
Brugia malayi Immunoglobulin I-set domain containing protein 0.0285 0.0077 0.0104
Giardia lamblia Kinase, CMGC GSK 0.1051 0.1035 0.9324
Schistosoma mansoni serine/threonine protein kinase 0.0316 0.0116 0.0285
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0424 0.0251 0.2424
Schistosoma mansoni serine/threonine protein kinase 0.0506 0.0354 0.0869
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0404 0.0226 0.0389
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0271 0.0059 0.0101
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0316 0.0116 0.02
Echinococcus granulosus NCK adaptor protein 0.0359 0.017 0.0292
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0254 0.0038 0.0051
Trichomonas vaginalis CAMK family protein kinase 0.0289 0.0082 0.0742
Echinococcus multilocularis MAM 0.0308 0.0106 0.0106
Trichomonas vaginalis AGC family protein kinase 0.0228 0.0006 0.0051
Echinococcus multilocularis neurotracting:lsamp:neurotrimin:obcam 0.0254 0.0038 0.0038
Trichomonas vaginalis AGC family protein kinase 0.0658 0.0544 0.4897
Echinococcus granulosus casein kinase I delta 0.0561 0.0422 0.0728
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0396 0.0215 0.0215
Entamoeba histolytica PH domain containing protein kinase, putative 0.071 0.0609 0.5884
Loa Loa (eye worm) hypothetical protein 0.0829 0.0757 0.1021
Echinococcus granulosus tyrosine kinase 0.083 0.0759 0.1308
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0989 0.0957 0.0957
Echinococcus granulosus tyrosine protein kinase Srms 0.0829 0.0757 0.1304
Schistosoma mansoni septate junction protein 0.0254 0.0038 0.0093
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0583 0.0449 0.1104
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0553 0.0412 0.0412
Brugia malayi cyclin-dependent kinase 7 homolog 0.064 0.0521 0.0702
Loa Loa (eye worm) hypothetical protein 0.0612 0.0486 0.0655
Loa Loa (eye worm) hypothetical protein 0.0308 0.0106 0.0143
Entamoeba histolytica protein kinase, putative 0.0502 0.0349 0.3367
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.0253 0.0037 0.0356
Onchocerca volvulus 0.1051 0.1035 0.1396
Entamoeba histolytica protein kinase domain containing protein 0.1051 0.1035 1
Trypanosoma cruzi mitogen-activated protein kinase kinase 5 0.1111 0.111 0.1913
Giardia lamblia Kinase, CK1 Casein kinase 0.0561 0.0422 0.3804
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0348 0.0156 0.151
Trichomonas vaginalis STE family protein kinase 0.1111 0.111 1
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0314 0.0114 0.0153
Echinococcus multilocularis casein kinase I alpha 0.0561 0.0422 0.0422
Schistosoma mansoni adapter molecule crk 0.0359 0.017 0.0417
Trichomonas vaginalis CAMK family protein kinase 0.0316 0.0116 0.1043
Trypanosoma brucei SNF1-related protein kinases, putative 0.0316 0.0116 0.02
Schistosoma mansoni serine/threonine protein kinase 0.0669 0.0558 0.1371
Echinococcus multilocularis G protein coupled receptor kinase 6 0.1295 0.1341 0.1341
Echinococcus granulosus NDR protein kinase 0.0494 0.0339 0.0584
Schistosoma mansoni protein kinase 0.2258 0.2546 0.6256
Schistosoma mansoni protein kinase 0.0865 0.0802 0.1972
Echinococcus multilocularis tyrosine protein kinase Abl 0.1213 0.1238 0.1238
Trypanosoma cruzi casein kinase, putative 0.0561 0.0422 0.0728
Echinococcus granulosus serine:threonine protein kinase N2 0.1517 0.1618 0.2788
Trichomonas vaginalis CAMK family protein kinase 0.0316 0.0116 0.1043
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0669 0.0558 0.0961
Brugia malayi Protein kinase domain containing protein 0.0658 0.0544 0.0733
Schistosoma mansoni hypothetical protein 0.0308 0.0106 0.0261
Loa Loa (eye worm) hypothetical protein 0.0257 0.0041 0.0056
Schistosoma mansoni serine/threonine protein kinase 0.0608 0.0481 0.1181
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.1051 0.1035 0.1784
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0989 0.0957 0.0957
Echinococcus granulosus dual specificity protein kinase clk2 0.0928 0.0882 0.152
Onchocerca volvulus 0.0424 0.0251 0.0338
Echinococcus multilocularis cyclin dependent kinase 1 0.0404 0.0226 0.0226
Echinococcus granulosus cGMP dependent protein kinase 1 0.0249 0.0031 0.0054
Onchocerca volvulus 0.0413 0.0237 0.032
Toxoplasma gondii casein kinase I 0.0561 0.0422 0.408
Trichomonas vaginalis CAMK family protein kinase 0.0289 0.0082 0.0742
Trichomonas vaginalis CAMK family protein kinase 0.0316 0.0116 0.1043
Trichomonas vaginalis CAMK family protein kinase 0.0316 0.0116 0.1043
Plasmodium falciparum cGMP-dependent protein kinase 0.0249 0.0031 0.0304
Brugia malayi p70 ribosomal S6 kinase beta 0.0617 0.0492 0.0664
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.1306 0.1354 0.2333
Loa Loa (eye worm) TK/FER protein kinase 0.0725 0.0628 0.0846
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0249 0.0031 0.0031
Echinococcus granulosus serine:threonine kinase SAD 1 0.0316 0.0116 0.02
Entamoeba histolytica protein kinase domain containing protein 0.0331 0.0134 0.1296
Brugia malayi hypothetical protein 0.0584 0.0452 0.0609
Echinococcus granulosus titin 0.0351 0.016 0.0275
Echinococcus granulosus serine/threonine protein kinase 0.0311 0.011 0.0189
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0311 0.011 0.0189
Onchocerca volvulus 0.615 0.7416 1
Loa Loa (eye worm) hypothetical protein 0.0316 0.0116 0.0156
Echinococcus multilocularis cyclin dependent kinase 0.0404 0.0226 0.0226
Schistosoma mansoni tyrosine kinase 0.1232 0.1261 0.31
Giardia lamblia Kinase, CMGC GSK 0.1051 0.1035 0.9324
Schistosoma mansoni vesicular amine transporter 0.0553 0.0412 0.1014
Echinococcus multilocularis cyclin dependent kinase 9 0.0331 0.0134 0.0134
Loa Loa (eye worm) CMGC/CDK/CDK9 protein kinase 0.0331 0.0134 0.0181
Echinococcus granulosus tyrosine protein kinase Src64B 0.0989 0.0957 0.165
Trypanosoma brucei aurora B kinase 0.0545 0.0402 0.0693
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.0506 0.0354 0.0477
Onchocerca volvulus 0.2252 0.2538 0.3422
Loa Loa (eye worm) TK protein kinase 0.1478 0.1569 0.2116
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0675 0.0565 0.0565
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.1047 0.103 0.1774
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.0253 0.0037 0.005
Echinococcus granulosus serine:threonine protein kinase MARK2 0.047 0.0309 0.0532
Schistosoma mansoni kinase 0.0354 0.0163 0.0401
Entamoeba histolytica cell division protein kinase 2, putative 0.0436 0.0266 0.2569
Brugia malayi serine/threonine kinase 12 0.0545 0.0402 0.0542
Loa Loa (eye worm) TKL/LRRK protein kinase 0.0383 0.0199 0.0269
Loa Loa (eye worm) hypothetical protein 0.0553 0.0412 0.0556
Entamoeba histolytica protein kinase, putative 0.0494 0.0339 0.3274
Leishmania major protein kinase A catalytic subunit isoform 1 0.0669 0.0558 0.0961
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0494 0.0339 0.0339
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0289 0.0082 0.0142
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0371 0.0185 0.0319
Leishmania major protein kinase, putative 0.0545 0.0402 0.0693
Schistosoma mansoni serine/threonine protein kinase 0.0553 0.0412 0.1013
Entamoeba histolytica PH domain containing protein kinase, putative 0.071 0.0609 0.5884
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0669 0.0558 0.539
Trypanosoma cruzi casein kinase, putative 0.0561 0.0422 0.0728
Schistosoma mansoni serine/threonine protein kinase 0.0331 0.0134 0.033
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.056 0.0421 0.0568
Loa Loa (eye worm) hypothetical protein 0.0584 0.0452 0.0609
Brugia malayi serine/threonine-protein kinase plk-2 0.0289 0.0082 0.0111
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.1423 0.1501 0.2024
Trichomonas vaginalis AGC family protein kinase 0.0658 0.0544 0.4897
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0501 0.0347 0.0468
Trichomonas vaginalis STE family protein kinase 0.034 0.0146 0.1317
Trypanosoma cruzi cdc2-related kinase 3 0.0404 0.0226 0.0389
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0989 0.0957 0.0957
Schistosoma mansoni serine/threonine protein kinase 0.047 0.0309 0.0759
Trichomonas vaginalis CMGC family protein kinase 0.0253 0.0037 0.0332
Brugia malayi Protein kinase domain containing protein 0.0424 0.0251 0.0338
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0501 0.0347 0.0598
Loa Loa (eye worm) TK/ALK protein kinase 0.4464 0.5306 0.7155
Leishmania major protein kinase, putative 0.0501 0.0347 0.0598
Giardia lamblia Kinase, AGC PKA 0.0669 0.0558 0.5026
Giardia lamblia Kinase, PLK 0.0289 0.0082 0.0742
Entamoeba histolytica hypothetical protein 0.0377 0.0192 0.1855
Echinococcus granulosus calcium activated potassium channel 0.0309 0.0108 0.0185
Entamoeba histolytica hypothetical protein 0.1047 0.103 0.9948
Echinococcus multilocularis dual specificity protein kinase clk2 0.0928 0.0882 0.0882
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.0506 0.0354 0.0354
Brugia malayi Protein kinase domain containing protein 0.056 0.0421 0.0568
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0271 0.0059 0.0568
Schistosoma mansoni kinase 0.0331 0.0134 0.033
Trichomonas vaginalis CAMK family protein kinase 0.0316 0.0116 0.1043
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0404 0.0226 0.0304
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0669 0.0558 0.0961
Trichomonas vaginalis CAMK family protein kinase 0.0289 0.0082 0.0742
Schistosoma mansoni serine/threonine protein kinase 0.0928 0.0882 0.2167
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0891 0.0835 0.1126
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0669 0.0558 0.539
Loa Loa (eye worm) hypothetical protein 0.0254 0.0038 0.0051
Echinococcus granulosus tyrosine kinase 0.0424 0.0251 0.0432
Loa Loa (eye worm) CMGC/GSK protein kinase 0.1051 0.1035 0.1396
Brugia malayi P38 map kinase family protein 2 0.4862 0.5804 0.7826
Echinococcus granulosus Vam6:Vps39 protein 0.0612 0.0486 0.0837
Echinococcus granulosus cyclin dependent kinase 1 0.0404 0.0226 0.0389
Schistosoma mansoni growth factor receptor-bound protein 0.0359 0.017 0.0417
Schistosoma mansoni tyrosine kinase 0.2021 0.2249 0.5527
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0545 0.0402 0.3885
Echinococcus granulosus cyclin dependent kinase 19 0.158 0.1697 0.2925
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0669 0.0558 0.0558
Echinococcus multilocularis protein KINase family member (kin 25) 0.0732 0.0636 0.0636
Loa Loa (eye worm) TK/FER protein kinase 0.0424 0.0251 0.0338
Loa Loa (eye worm) hypothetical protein 0.0501 0.0347 0.0468
Trypanosoma cruzi casein kinase, putative 0.0561 0.0422 0.0728
Onchocerca volvulus 0.0424 0.0251 0.0338
Onchocerca volvulus 0.0612 0.0486 0.0655
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0501 0.0347 0.3352
Trypanosoma brucei cdc2-related kinase 1 0.0404 0.0226 0.0389
Brugia malayi Stress-activated protein kinase jnk-1 0.2666 0.3056 0.4121
Entamoeba histolytica casein kinase, putative 0.0561 0.0422 0.408
Plasmodium falciparum calcium-dependent protein kinase 3 0.0501 0.0347 0.3352
Echinococcus granulosus beta-adrenergic receptor kinase 0.0275 0.0065 0.0112
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.1047 0.103 0.1774
Schistosoma mansoni serine/threonine protein kinase 0.0275 0.0065 0.0159
Brugia malayi protein-tyrosine kinase 0.083 0.0759 0.1023
Schistosoma mansoni serine/threonine protein kinase 0.0726 0.0628 0.1544
Trichomonas vaginalis AGC family protein kinase 0.0545 0.0402 0.3623
Entamoeba histolytica hypothetical protein 0.0226 0.0003 0.0033
Trichomonas vaginalis AGC family protein kinase 0.0658 0.0544 0.4897
Schistosoma mansoni ephrin receptor 0.0287 0.0079 0.0195
Echinococcus multilocularis dual specificity 0.1047 0.103 0.103
Brugia malayi protein kinase C II. 0.0636 0.0516 0.0696
Loa Loa (eye worm) hypothetical protein 0.0309 0.0107 0.0144
Giardia lamblia Kinase, AGC AKT 0.09 0.0846 0.7625
Trichomonas vaginalis AGC family protein kinase 0.025 0.0033 0.0301
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0501 0.0347 0.3352
Entamoeba histolytica protein kinase, putative 0.1051 0.1035 1
Loa Loa (eye worm) hypothetical protein 0.0732 0.0636 0.0858
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.1263 0.1301 0.1301
Loa Loa (eye worm) hypothetical protein 0.0553 0.0412 0.0556
Brugia malayi Immunoglobulin I-set domain containing protein 0.0254 0.0038 0.0051
Loa Loa (eye worm) hypothetical protein 0.0556 0.0416 0.0561
Onchocerca volvulus Serine\/threonine kinase homolog 0.0289 0.0082 0.0111
Trichomonas vaginalis CAMK family protein kinase 0.0316 0.0116 0.1043
Loa Loa (eye worm) hypothetical protein 0.0899 0.0845 0.1139
Loa Loa (eye worm) AUR protein kinase 0.0545 0.0402 0.0542
Giardia lamblia Kinase, CAMK CAMKL 0.0348 0.0156 0.1405
Brugia malayi Serine/threonine-protein kinase SULU 0.2568 0.2934 0.3956
Leishmania major protein kinase A catalytic subunit 0.0669 0.0558 0.0961
Echinococcus granulosus serine:threonine protein kinase MARK2 0.047 0.0309 0.0532
Brugia malayi Protein kinase domain containing protein 0.615 0.7416 1
Echinococcus multilocularis beta adrenergic receptor kinase 0.0275 0.0065 0.0065
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0928 0.0882 0.152
Echinococcus granulosus contactin 0.0285 0.0077 0.0133
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0371 0.0185 0.0319
Trypanosoma brucei polo-like protein kinase 0.0289 0.0082 0.0142
Echinococcus granulosus ephrin type A receptor 4 A 0.0287 0.0079 0.0137
Schistosoma mansoni serine/threonine protein kinase 0.0404 0.0226 0.0555
Brugia malayi bone morphogenetic protein type 1 receptor 0.0865 0.0802 0.1082
Brugia malayi Temporarily assigned gene name protein 59 0.0612 0.0486 0.0655
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.083 0.0759 0.1308
Loa Loa (eye worm) STE/STE7/MEK1 protein kinase 0.1111 0.111 0.1497
Brugia malayi Immunoglobulin I-set domain containing protein 0.0351 0.016 0.0215
Echinococcus granulosus cyclin dependent kinase 0.0404 0.0226 0.0389
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.1051 0.1035 0.1784
Entamoeba histolytica protein kinase, putative 0.0545 0.0402 0.3885
Schistosoma mansoni protein kinase 0.0371 0.0185 0.0455
Brugia malayi hypothetical protein 0.0424 0.0251 0.0338
Loa Loa (eye worm) TK/KIN16 protein kinase 0.3111 0.3612 0.4871
Brugia malayi Protein kinase domain containing protein 0.0928 0.0882 0.1189
Brugia malayi Doublecortin family protein 0.0265 0.0052 0.007
Schistosoma mansoni serine/threonine protein kinase 0.0316 0.0116 0.0285
Entamoeba histolytica tyrosin kinase, putative 0.0263 0.0049 0.0478
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0501 0.0347 0.0347
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0612 0.0486 0.0837
Brugia malayi putative serine/threonine kinase SADA gamma 0.0316 0.0116 0.0156
Echinococcus multilocularis neuroglian 0.0285 0.0077 0.0077
Brugia malayi SH2 domain containing protein 0.0725 0.0628 0.0846
Brugia malayi Protein kinase domain containing protein 0.1946 0.2155 0.2906
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0669 0.0558 0.0961
Echinococcus multilocularis epidermal growth factor receptor 0.0794 0.0713 0.0713
Echinococcus granulosus hemicentin 1 0.0254 0.0038 0.0065
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.034 0.0146 0.0146
Onchocerca volvulus 0.0829 0.0757 0.1021
Brugia malayi Cam kinase protein 1 0.0501 0.0347 0.0468
Loa Loa (eye worm) hypothetical protein 0.0669 0.0558 0.0752
Echinococcus granulosus cyclin dependent kinase 9 0.0363 0.0174 0.03
Onchocerca volvulus 0.0243 0.0025 0.0033
Loa Loa (eye worm) TK protein kinase 0.083 0.0759 0.1023
Echinococcus multilocularis calcium activated potassium channel 0.0309 0.0108 0.0108
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.2258 0.2546 0.4387
Schistosoma mansoni serine/threonine protein kinase 0.1423 0.1501 0.3688
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.1811 0.1986 0.1986
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0376 0.0191 0.0258
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.2046 0.228 0.3075
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.1051 0.1035 0.1035
Brugia malayi probable protein kinase 0.1474 0.1564 0.2109
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0928 0.0882 0.852
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0254 0.0038 0.0051
Brugia malayi Tyrosine-protein kinase abl-1 0.1213 0.1238 0.167
Brugia malayi Dual specificity mitogen-activated protein kinase kinase mek-2 0.1111 0.111 0.1497
Entamoeba histolytica protein kinase domain containing protein 0.0371 0.0185 0.1788
Leishmania major protein kinase, putative 0.0928 0.0882 0.152
Loa Loa (eye worm) CMGC/CDK/CDK7 protein kinase 0.0608 0.0481 0.0648
Brugia malayi protein kinase C3,putative 0.037 0.0184 0.0248
Echinococcus multilocularis hemicentin 1 0.0254 0.0038 0.0038
Echinococcus multilocularis tyrosine protein kinase Fyn 0.083 0.0759 0.0759
Echinococcus granulosus dual specificity 0.0253 0.0037 0.0064
Schistosoma mansoni serine/threonine protein kinase 0.0314 0.0114 0.0279
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.1306 0.1354 0.1354
Echinococcus multilocularis mitogen activated protein kinase 11 0.4862 0.5804 0.5804
Echinococcus multilocularis c Jun NH2 terminal kinase 0.2666 0.3056 0.3056
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0553 0.0412 0.1014
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0635 0.0515 0.0887
Brugia malayi hypothetical protein 0.0308 0.0106 0.0143
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0341 0.0147 0.0253
Brugia malayi Protein kinase domain containing protein 0.0695 0.059 0.0795
Trichomonas vaginalis AGC family protein kinase 0.0535 0.039 0.3514
Plasmodium falciparum protein kinase 5 0.0404 0.0226 0.2181
Giardia lamblia Kinase, STE STE20 0.034 0.0146 0.1317
Brugia malayi Protein kinase domain 0.034 0.0146 0.0197
Schistosoma mansoni cell adhesion molecule 0.0666 0.0554 0.1361
Schistosoma mansoni serine/threonine protein kinase 0.0404 0.0226 0.0555
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.4862 0.5804 1
Echinococcus granulosus TGF-beta receptor type-1 0.0789 0.0708 0.1219
Echinococcus multilocularis casein kinase I alpha 0.0561 0.0422 0.0422
Schistosoma mansoni serine/threonine-protein kinase 0.0311 0.011 0.027
Echinococcus multilocularis neuroglian 0.0725 0.0628 0.0628
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0501 0.0347 0.0468
Entamoeba histolytica cell division protein kinase 2, putative 0.0404 0.0226 0.2181
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0725 0.0628 0.0628
Echinococcus granulosus maternal embryonic leucine zipper kinase 0.0229 0.0007 0.0012
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.0316 0.0116 0.02
Trichomonas vaginalis CAMK family protein kinase 0.0391 0.0209 0.1887
Brugia malayi Immunoglobulin I-set domain containing protein 0.0285 0.0077 0.0104
Schistosoma mansoni serine/threonine kinase 0.0423 0.025 0.0613
Schistosoma mansoni neuroglian 0.0285 0.0077 0.0189
Echinococcus granulosus defective proboscis extension response 0.0553 0.0412 0.0711
Echinococcus granulosus tyrosine protein kinase Fyn 0.0989 0.0957 0.165
Echinococcus granulosus cyclin dependent kinase 5 0.0404 0.0226 0.0389
Schistosoma mansoni protein kinase 0.034 0.0146 0.0359
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.025 0.0033 0.0323
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.076 0.0671 0.1156
Schistosoma mansoni ephrin receptor 0.0255 0.0039 0.0096
Onchocerca volvulus Basement membrane proteoglycan homolog 0.0254 0.0038 0.0051
Trichomonas vaginalis CAMK family protein kinase 0.0316 0.0116 0.1043
Schistosoma mansoni serine/threonine protein kinase 0.1247 0.128 0.3146
Echinococcus multilocularis N chimaerin 0.0341 0.0147 0.0147
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0669 0.0558 0.0961
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0341 0.0147 0.036
Schistosoma mansoni serine/threonine protein kinase 0.0501 0.0347 0.0853
Loa Loa (eye worm) hypothetical protein 0.0584 0.0452 0.0609
Brugia malayi hypothetical protein 0.0547 0.0405 0.0546
Echinococcus multilocularis c src tyrosine kinase 0.0583 0.0449 0.0449
Trypanosoma cruzi casein kinase, putative 0.0561 0.0422 0.0728
Entamoeba histolytica protein kinase domain containing protein 0.1051 0.1035 1
Loa Loa (eye worm) AGC/PKA protein kinase 0.0669 0.0558 0.0752
Echinococcus granulosus tyrosine protein kinase Blk 0.083 0.0759 0.1308
Entamoeba histolytica protein kinase, putative 0.0658 0.0544 0.5251
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.2086 0.233 0.4015
Trichomonas vaginalis CAMK family protein kinase 0.0229 0.0007 0.0065
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0249 0.0031 0.0304
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0494 0.0339 0.0457
Echinococcus granulosus protein tyrosine kinase 0.3476 0.407 0.7012
Brugia malayi Egg laying defective protein 4 0.0249 0.0031 0.0042
Echinococcus granulosus protein kinase shaggy 0.1051 0.1035 0.1784
Entamoeba histolytica protein kinase 2, putative 0.0271 0.0059 0.0568
Entamoeba histolytica protein kinase, putative 0.0226 0.0003 0.0033
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0948 0.0906 0.0906
Entamoeba histolytica p21-activated kinase 0.0381 0.0197 0.1907
Trypanosoma cruzi polo-like protein kinase, putative 0.0289 0.0082 0.0142
Plasmodium falciparum casein kinase 1 0.0561 0.0422 0.408
Echinococcus granulosus activin receptor type 0.3647 0.4283 0.738
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.1247 0.128 0.2206
Echinococcus granulosus tyrosine protein kinase Src42A 0.0989 0.0957 0.165
Trichomonas vaginalis CMGC family protein kinase 0.0404 0.0226 0.2034
Echinococcus granulosus serine:threonine protein kinase TAO1 0.2568 0.2934 0.5055
Echinococcus granulosus epidermal growth factor receptor 0.0794 0.0713 0.1229
Plasmodium falciparum calcium-dependent protein kinase 4 0.0501 0.0347 0.3352
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0501 0.0347 0.0347
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.4862 0.5804 1
Echinococcus multilocularis raf serine:threonine protein kinase 0.0364 0.0175 0.0175
Entamoeba histolytica PH domain containing protein kinase, putative 0.0311 0.011 0.1062
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0371 0.0185 0.0319
Echinococcus multilocularis STE20 serine:threonine protein kinase 0.0606 0.0478 0.0478
Plasmodium vivax protein kinase Crk2 0.0404 0.0226 0.2181
Loa Loa (eye worm) hypothetical protein 0.07 0.0597 0.0805
Loa Loa (eye worm) TKL/STKR/TYPE2 protein kinase 0.0695 0.059 0.0795
Entamoeba histolytica PH domain containing protein kinase, putative 0.0311 0.011 0.1062
Brugia malayi Protein kinase domain containing protein 0.0383 0.0199 0.0269
Schistosoma mansoni serine/threonine protein kinase 0.1517 0.1618 0.3976
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0989 0.0957 0.165
Loa Loa (eye worm) CAMK/PIM protein kinase 0.2046 0.228 0.3075
Loa Loa (eye worm) hypothetical protein 0.071 0.0609 0.0821
Trichomonas vaginalis STE family protein kinase 0.034 0.0146 0.1317
Brugia malayi Protein kinase domain containing protein 0.1047 0.103 0.1389
Onchocerca volvulus 0.0578 0.0443 0.0598
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0285 0.0077 0.0133
Brugia malayi Hr1 repeat family protein 0.1517 0.1618 0.2182
Entamoeba histolytica protein kinase, putative 0.0319 0.0119 0.1153
Loa Loa (eye worm) CAMK/PHK protein kinase 0.0278 0.0068 0.0092
Brugia malayi Immunoglobulin I-set domain containing protein 0.0418 0.0243 0.0328
Trichomonas vaginalis CAMK family protein kinase 0.0289 0.0082 0.0742
Giardia lamblia Kinase, CMGC CDK 0.0404 0.0226 0.2034
Schistosoma mansoni nephrin 0.0285 0.0077 0.0189
Loa Loa (eye worm) camk/dcamkl protein kinase 0.0265 0.0052 0.007
Echinococcus multilocularis maternal embryonic leucine zipper kinase 0.0229 0.0007 0.0007
Echinococcus multilocularis tyrosine protein kinase HCK 0.063 0.0508 0.0508
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.2666 0.3056 0.4121
Echinococcus multilocularis insulin receptor 0.1232 0.1261 0.1261
Loa Loa (eye worm) hypothetical protein 0.0285 0.0077 0.0104
Schistosoma mansoni serine/threonine protein kinase 0.0948 0.0906 0.2227
Echinococcus multilocularis serine:threonine protein kinase 3 0.037 0.0183 0.0183
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0289 0.0082 0.0111
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0617 0.0492 0.0664
Entamoeba histolytica protein kinase, putative 0.0253 0.0037 0.0356
Trichomonas vaginalis CAMK family protein kinase 0.0316 0.0116 0.1043
Trypanosoma brucei mitogen-activated protein kinase kinase 5 0.1111 0.111 0.1913
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0977 0.0942 0.1271
Onchocerca volvulus 0.0306 0.0104 0.014
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0243 0.0024 0.0032
Trichomonas vaginalis AGC family protein kinase 0.0658 0.0544 0.4897
Schistosoma mansoni serine/threonine protein kinase 0.0545 0.0402 0.0988
Brugia malayi Variant SH3 domain containing protein 0.0243 0.0024 0.0032
Schistosoma mansoni tyrosine kinase 0.0636 0.0516 0.1268
Schistosoma mansoni serine/threonine protein kinase 0.0669 0.0558 0.1371
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0989 0.0957 0.0957
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0928 0.0882 0.152
Brugia malayi Protein kinase domain containing protein 0.1232 0.1261 0.1701
Echinococcus multilocularis dual specificity 0.0253 0.0037 0.0037
Schistosoma mansoni protein kinase 0.0371 0.0185 0.0455
Brugia malayi Protein kinase domain containing protein 0.0306 0.0104 0.014
Brugia malayi Protein kinase domain containing protein 0.2046 0.228 0.3075
Onchocerca volvulus 0.0726 0.0628 0.0847
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0285 0.0077 0.0077
Schistosoma mansoni protein kinase 0.0371 0.0185 0.0455
Echinococcus granulosus c src tyrosine kinase 0.0583 0.0449 0.0774
Entamoeba histolytica protein kinase domain containing protein 0.0253 0.0037 0.0356
Trichomonas vaginalis AGC family protein kinase 0.0527 0.0379 0.3414
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0348 0.0156 0.1507
Loa Loa (eye worm) AUR protein kinase 0.0545 0.0402 0.0542
Echinococcus granulosus glycogen synthase kinase 3 beta 0.1051 0.1035 0.1784
Schistosoma mansoni serine/threonine protein kinase 0.2046 0.228 0.5603
Loa Loa (eye worm) TK/FER protein kinase 0.0424 0.0251 0.0338
Giardia lamblia Kinase, CAMK CAMKL 0.0348 0.0156 0.1405
Brugia malayi map kinase activated protein kinase protein 2 0.0506 0.0354 0.0477
Loa Loa (eye worm) AGC/AKT protein kinase 0.0658 0.0544 0.0733
Echinococcus granulosus twitchin 0.0873 0.0813 0.14
Echinococcus granulosus mitogen activated protein kinase 11 0.4862 0.5804 1
Toxoplasma gondii aurora kinase 0.0545 0.0402 0.3885
Echinococcus multilocularis serine:threonine protein kinase 0.0309 0.0107 0.0107
Echinococcus multilocularis serine:threonine protein kinase 0.0309 0.0107 0.0107
Onchocerca volvulus 0.0308 0.0106 0.0143
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.1423 0.1501 0.2024
Brugia malayi Protein kinase domain containing protein 0.071 0.0609 0.0821
Plasmodium falciparum calcium-dependent protein kinase 5 0.0501 0.0347 0.3352
Brugia malayi protein unc-22 0.0351 0.016 0.0215
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.1757 0.1919 0.2588
Giardia lamblia Kinase, CMGC CLK 0.0928 0.0882 0.7944
Echinococcus granulosus cyclin dependent kinase 9 0.0331 0.0134 0.0231
Entamoeba histolytica protein kinase domain containing protein 0.0263 0.0049 0.0478
Brugia malayi Protein kinase domain containing protein 0.4466 0.5308 0.7157
Plasmodium falciparum glycogen synthase kinase 3 0.1051 0.1035 1
Loa Loa (eye worm) CAMK protein kinase 0.0351 0.016 0.0215
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0285 0.0077 0.0077
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0561 0.0422 0.057
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0494 0.0339 0.0584
Schistosoma mansoni serine/threonine protein kinase 0.0675 0.0565 0.1389
Loa Loa (eye worm) TK/ABL protein kinase 0.2073 0.2314 0.3121
Loa Loa (eye worm) gastrulation defective protein 1 0.1432 0.1512 0.204
Schistosoma mansoni roundabout 0.0254 0.0038 0.0093
Plasmodium falciparum protein serine/threonine kinase-1 0.0928 0.0882 0.852
Trichomonas vaginalis CMGC family protein kinase 0.0404 0.0226 0.2034
Echinococcus multilocularis epidermal growth factor receptor 0.0932 0.0886 0.0886
Echinococcus multilocularis serine:threonine protein kinase N2 0.1517 0.1618 0.1618
Echinococcus multilocularis mitogen activated protein kinase 14 0.4862 0.5804 0.5804
Schistosoma mansoni serine/threonine protein kinase 0.0316 0.0116 0.0285
Brugia malayi Protein kinase domain containing protein 0.2086 0.233 0.3142
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.1757 0.1919 0.2588
Trypanosoma cruzi Protein kinase B 0.0311 0.011 0.0189
Echinococcus granulosus MAM 0.0308 0.0106 0.0183
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0359 0.017 0.0229
Echinococcus granulosus casein kinase I alpha 0.0561 0.0422 0.0728
Echinococcus granulosus raf serine:threonine protein kinase 0.0364 0.0175 0.0302
Toxoplasma gondii AGC kinase 0.0617 0.0492 0.4757
Echinococcus multilocularis leucine rich repeat serine:threonine protein 0.0383 0.0199 0.0199
Onchocerca volvulus 0.034 0.0145 0.0196
Loa Loa (eye worm) hypothetical protein 0.0241 0.0022 0.003
Plasmodium vivax serine/threonine kinase-1, putative 0.0928 0.0882 0.852
Echinococcus granulosus tyrosine protein kinase shark 0.0636 0.0516 0.0889
Echinococcus granulosus tyrosine protein kinase Lyn 0.1137 0.1142 0.1968
Trichomonas vaginalis STE family protein kinase 0.034 0.0146 0.1317
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.4501 0.5352 0.9223
Echinococcus granulosus serine:threonine protein kinase 0.0309 0.0107 0.0184
Schistosoma mansoni serine/threonine protein kinase 0.032 0.012 0.0296
Trichomonas vaginalis AGC family protein kinase 0.0545 0.0402 0.3623
Schistosoma mansoni tyrosine kinase 0.1306 0.1354 0.3327
Brugia malayi serine/threonine protein kinase 6 0.0545 0.0402 0.0542
Echinococcus multilocularis tyrosine protein kinase Blk 0.083 0.0759 0.0759
Schistosoma mansoni tyrosine kinase 0.057 0.0434 0.1066
Loa Loa (eye worm) TK/FER protein kinase 0.0424 0.0251 0.0338
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0418 0.0243 0.0328
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.047 0.0309 0.0309
Echinococcus multilocularis casein kinase I delta 0.0561 0.0422 0.0422
Brugia malayi Protein kinase domain containing protein 0.0327 0.0129 0.0174
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.1047 0.103 0.1774
Echinococcus multilocularis serine:threonine protein kinase receptor R3 0.0789 0.0708 0.0708
Echinococcus multilocularis 0.0781 0.0697 0.0697
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0249 0.0031 0.0031
Brugia malayi Protein kinase domain containing protein 0.0494 0.0339 0.0457
Leishmania major mitogen-activated protein kinase kinase 5, putative;with=GeneDB:LmxM36.0860 0.1111 0.111 0.1913
Brugia malayi Variant SH3 domain containing protein 0.0341 0.0147 0.0198
Echinococcus multilocularis roundabout 2 0.0285 0.0077 0.0077
Trichomonas vaginalis CAMK family protein kinase 0.0316 0.0116 0.1043
Schistosoma mansoni protein kinase 0.0561 0.0422 0.1038
Schistosoma mansoni serine/threonine protein kinase 0.0316 0.0116 0.0285
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0989 0.0957 0.0957
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.1051 0.1035 1
Echinococcus multilocularis casein kinase I alpha 0.0561 0.0422 0.0422
Echinococcus multilocularis phosphorylase kinase gamma subunit 0.0278 0.0068 0.0068
Schistosoma mansoni cell adhesion molecule 0.0285 0.0077 0.0189
Loa Loa (eye worm) TK protein kinase 0.063 0.0508 0.0685
Schistosoma mansoni tyrosine kinase 0.0583 0.0449 0.1104
Loa Loa (eye worm) hypothetical protein 0.0508 0.0356 0.048
Loa Loa (eye worm) hypothetical protein 0.0502 0.0348 0.0469
Brugia malayi Immunoglobulin I-set domain containing protein 0.0584 0.0452 0.0609
Brugia malayi Fes/CIP4 homology domain containing protein 0.0729 0.0632 0.0852
Schistosoma mansoni serine/threonine protein kinase 0.0494 0.0339 0.0833
Schistosoma mansoni tyrosine kinase 0.1232 0.1261 0.31
Loa Loa (eye worm) CMGC/CDK/CDK8 protein kinase 0.158 0.1697 0.2289
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0669 0.0558 0.0558
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0891 0.0835 0.0835
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0341 0.0147 0.036
Echinococcus granulosus dual specificity 0.0253 0.0037 0.0064
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.2568 0.2934 0.2934
Plasmodium falciparum calcium-dependent protein kinase 1 0.0501 0.0347 0.3352
Brugia malayi STE20-like kinase MST 0.037 0.0183 0.0247
Brugia malayi Protein kinase domain containing protein 0.158 0.1697 0.2289
Trichomonas vaginalis CMGC family protein kinase 0.0253 0.0037 0.0332
Trypanosoma brucei protein kinase, putative 0.0371 0.0185 0.0319
Echinococcus multilocularis peroxidasin 0.0257 0.0041 0.0041
Schistosoma mansoni serine/threonine protein kinase 0.1047 0.103 0.253
Loa Loa (eye worm) hypothetical protein 0.0254 0.0038 0.0051
Entamoeba histolytica protein kinase, putative 0.036 0.017 0.1647
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0669 0.0558 0.0558
Trichomonas vaginalis CAMK family protein kinase 0.0316 0.0116 0.1043
Loa Loa (eye worm) hypothetical protein 0.0458 0.0293 0.0395
Trichomonas vaginalis CK1 family protein kinase 0.0561 0.0422 0.3804
Echinococcus multilocularis expressed conserved protein 0.0249 0.0031 0.0031
Echinococcus multilocularis serine threonine protein kinase 0.0535 0.039 0.039
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0289 0.0082 0.0082
Entamoeba histolytica protein kinase , putative 0.0545 0.0402 0.3885
Echinococcus granulosus insulin growth factor 1 receptor beta 0.1263 0.1301 0.2241
Schistosoma mansoni protein kinase 0.2258 0.2546 0.6256
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0228 0.0006 0.0008
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.1982 0.22 0.2967
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0561 0.0422 0.057
Echinococcus multilocularis ephrin type A receptor 4 A 0.0287 0.0079 0.0079
Entamoeba histolytica serine/threonine protein kinase, putative 0.0316 0.0116 0.1119
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0545 0.0402 0.3885
Echinococcus granulosus tyrosine protein kinase ABL1 0.2073 0.2314 0.3988
Trichomonas vaginalis AGC family protein kinase 0.0494 0.0339 0.3053
Leishmania major protein kinase, putative 0.0371 0.0185 0.0319
Echinococcus granulosus titin 0.0351 0.016 0.0275
Onchocerca volvulus Tyrosine kinase homolog 0.2647 0.3033 0.409
Trichomonas vaginalis STE family protein kinase 0.0319 0.0119 0.1075
Echinococcus multilocularis tyrosine kinase 0.0424 0.0251 0.0251
Schistosoma mansoni tyrosine kinase 0.0435 0.0265 0.0651
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0501 0.0347 0.0468
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0669 0.0558 0.0752
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0669 0.0558 0.0961
Schistosoma mansoni tyrosine kinase 0.0583 0.0449 0.1104
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0404 0.0226 0.0389
Schistosoma mansoni serine/threonine protein kinase 0.0669 0.0558 0.1371
Schistosoma mansoni serine/threonine protein kinase 0.0588 0.0456 0.1122
Echinococcus granulosus roundabout 2 0.0285 0.0077 0.0133
Onchocerca volvulus 0.0561 0.0422 0.057
Echinococcus granulosus cGMP dependent protein kinase 1 0.0249 0.0031 0.0054
Brugia malayi Protein kinase c protein 2 0.0329 0.0131 0.0177
Echinococcus granulosus tyrosine protein kinase Btk29A 0.2165 0.2429 0.4186
Echinococcus granulosus TGF beta receptor type 1 0.0789 0.0708 0.1219
Schistosoma mansoni vam6/vps39 related 0.0612 0.0486 0.1194
Trichomonas vaginalis CMGC family protein kinase 0.0253 0.0037 0.0332
Brugia malayi Protein kinase domain containing protein 0.0726 0.0629 0.0848
Loa Loa (eye worm) hypothetical protein 0.0841 0.0772 0.1041
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0316 0.0116 0.02
Plasmodium falciparum calcium-dependent protein kinase 2 0.0501 0.0347 0.3352
Trypanosoma cruzi cdc2-related kinase 1 0.0404 0.0226 0.0389
Loa Loa (eye worm) STE/STE20/SLK protein kinase 0.0306 0.0104 0.014
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.037 0.0183 0.0247
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.1295 0.1341 0.1809
Schistosoma mansoni septate junction protein 0.0254 0.0038 0.0093
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.0862 0.0798 0.1077
Schistosoma mansoni protein kinase 0.0319 0.0119 0.0293
Schistosoma mansoni protein kinase C mu 0.0977 0.0942 0.2315
Echinococcus granulosus calcium dependent protein kinase 0.0353 0.0162 0.0279
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.0612 0.0486 0.0486
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0341 0.0147 0.0198
Echinococcus granulosus leucine rich repeat serine:threonine protein 0.0382 0.0198 0.0341
Trichomonas vaginalis CAMK family protein kinase 0.0289 0.0082 0.0742
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0522 0.0373 0.0373
Echinococcus granulosus tyrosine protein kinase Fyn 0.0989 0.0957 0.165
Echinococcus granulosus N chimaerin 0.0341 0.0147 0.0253
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0695 0.059 0.0795
Entamoeba histolytica protein kinase domain containing protein 0.1047 0.103 0.9948
Schistosoma mansoni serine/threonine protein kinase 0.0928 0.0882 0.2167
Brugia malayi Variant SH3 domain containing protein 0.0359 0.017 0.0229
Loa Loa (eye worm) hypothetical protein 0.07 0.0597 0.0805
Entamoeba histolytica casein kinase 1, putative 0.0561 0.0422 0.408
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0928 0.0882 0.152
Brugia malayi Immunoglobulin I-set domain containing protein 0.0254 0.0038 0.0051
Loa Loa (eye worm) TK/FAK protein kinase 0.3515 0.4118 0.5553
Loa Loa (eye worm) hypothetical protein 0.0689 0.0582 0.0785
Onchocerca volvulus 0.0424 0.0251 0.0338
Echinococcus multilocularis titin 0.0351 0.016 0.016
Schistosoma mansoni serine/threonine protein kinase 0.0309 0.0108 0.0264
Schistosoma mansoni tyrosine kinase 0.0794 0.0713 0.1753
Echinococcus multilocularis roundabout 2 0.0285 0.0077 0.0077
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.4862 0.5804 0.7826
Brugia malayi serine/threonine-protein kinase PAK 7 0.1982 0.22 0.2967
Echinococcus multilocularis NCK adaptor protein 0.0374 0.0188 0.0188
Schistosoma mansoni serine/threonine kinase 0.0494 0.0339 0.0833
Trypanosoma brucei protein kinase, putative 0.023 0.0008 0.0015
Echinococcus multilocularis serine:threonine protein kinase N2 0.0494 0.0339 0.0339
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0501 0.0347 0.3352
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0669 0.0558 0.0558
Echinococcus granulosus MAP kinase activated protein kinase 2 0.0506 0.0354 0.0609
Echinococcus granulosus protein kinase c epsilon type 0.0636 0.0516 0.0889
Echinococcus multilocularis dual specificity mitogen activated protein 0.1111 0.111 0.111
Entamoeba histolytica protein kinase, putative 0.063 0.0508 0.4908
Loa Loa (eye worm) hypothetical protein 0.0359 0.017 0.0229
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0501 0.0347 0.0598
Onchocerca volvulus 0.0424 0.0251 0.0338
Echinococcus granulosus hypothetical protein 0.0781 0.0697 0.1201
Trichomonas vaginalis AGC family protein kinase 0.0669 0.0558 0.5026
Echinococcus granulosus casein kinase I gamma 0.0327 0.0129 0.0222
Schistosoma mansoni serine/threonine protein kinase 0.0253 0.0037 0.0091
Trichomonas vaginalis CAMK family protein kinase 0.0316 0.0116 0.1043
Trichomonas vaginalis CMGC family protein kinase 0.0404 0.0226 0.2034
Schistosoma mansoni serine/threonine protein kinase 0.0494 0.0339 0.0833
Echinococcus multilocularis protein tyrosine kinase 0.3476 0.407 0.407
Schistosoma mansoni protein kinase 0.1474 0.1564 0.3843
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.2258 0.2546 0.2546
Leishmania major casein kinase, putative 0.0561 0.0422 0.0728
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0545 0.0402 0.0693
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0794 0.0713 0.1229
Loa Loa (eye worm) AGC/PKA protein kinase 0.0669 0.0558 0.0752
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.034 0.0146 0.0252
Schistosoma mansoni serine/threonine protein kinase 0.0561 0.0422 0.1038
Schistosoma mansoni cell adhesion molecule 0.0285 0.0077 0.0189
Echinococcus granulosus rho-associated protein kinase 1 0.0726 0.0628 0.1083
Loa Loa (eye worm) G protein-coupled receptor kinase 1 0.1295 0.1341 0.1809
Echinococcus granulosus serine:threonine protein kinase 3 0.037 0.0183 0.0316
Brugia malayi Immunoglobulin I-set domain containing protein 0.0254 0.0038 0.0051
Loa Loa (eye worm) AGC/NDR protein kinase 0.0494 0.0339 0.0457
Brugia malayi hypothetical protein 0.0612 0.0486 0.0655
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0669 0.0558 0.0961
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.076 0.0671 0.0671
Loa Loa (eye worm) hypothetical protein 0.087 0.0808 0.109
Loa Loa (eye worm) protein kinase domain-containing protein 0.0327 0.0129 0.0174
Entamoeba histolytica protein kinase, putative 0.0658 0.0544 0.5251
Echinococcus multilocularis serine:threonine protein kinase 38 0.0494 0.0339 0.0339
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0433 0.0262 0.0353
Brugia malayi Protein kinase domain containing protein 0.071 0.0609 0.0821
Trypanosoma cruzi aurora B kinase, putative 0.0545 0.0402 0.0693
Giardia lamblia Kinase, NEK 0.025 0.0033 0.0301
Echinococcus granulosus casein kinase I alpha 0.0561 0.0422 0.0728
Trypanosoma cruzi cdc2-related kinase 1 0.0404 0.0226 0.0389
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0989 0.0957 0.0957
Brugia malayi Homeodomain interacting protein kinase protein 1 0.0316 0.0116 0.0156
Brugia malayi Immunoglobulin I-set domain containing protein 0.0254 0.0038 0.0051
Echinococcus multilocularis protein kinase shaggy 0.1051 0.1035 0.1035
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.071 0.0609 0.0821
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0404 0.0226 0.0304
Brugia malayi Protein kinase domain containing protein 0.0424 0.0251 0.0338
Entamoeba histolytica protein kinase, putative 0.036 0.017 0.1647
Entamoeba histolytica hypothetical protein 0.0226 0.0003 0.0033
Plasmodium vivax calcium-dependent protein kinase, putative 0.0501 0.0347 0.3352
Entamoeba histolytica hypothetical protein 0.0226 0.0003 0.0033
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0371 0.0185 0.0185
Brugia malayi RhoGAP domain containing protein 0.0341 0.0147 0.0198
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0371 0.0185 0.0319
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0494 0.0339 0.0339
Echinococcus multilocularis tyrosine protein kinase Srms 0.083 0.0759 0.0759
Echinococcus granulosus Protein kinase C brain isozyme 0.0675 0.0565 0.0974
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.4862 0.5804 1
Trichomonas vaginalis CMGC family protein kinase 0.0928 0.0882 0.7944
Toxoplasma gondii histone kinase SNF1, putative 0.0316 0.0116 0.1119
Schistosoma mansoni protein kinase 0.1111 0.111 0.2728
Trypanosoma brucei protein kinase, putative 0.1051 0.1035 0.1784
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.2046 0.228 0.228
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0636 0.0516 0.0696
Echinococcus multilocularis rho associated protein kinase 0.0726 0.0628 0.0628
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0316 0.0116 0.0156
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.1247 0.128 0.1726
Trypanosoma cruzi cdc2-related kinase 3 0.0404 0.0226 0.0389
Loa Loa (eye worm) TK/FER protein kinase 0.0424 0.0251 0.0338
Echinococcus granulosus tyrosine protein kinase Fyn 0.0989 0.0957 0.165
Echinococcus granulosus dual specificity 0.1047 0.103 0.1774
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0669 0.0558 0.0961
Brugia malayi Tyrosine-protein kinase abl-1 0.1019 0.0995 0.1341
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0359 0.017 0.0417
Loa Loa (eye worm) TK/FER protein kinase 0.0424 0.0251 0.0338
Echinococcus granulosus protein kinase c iota type 0.0717 0.0617 0.1064
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0669 0.0558 0.539
Schistosoma mansoni serine/threonine protein kinase 0.0278 0.0068 0.0167
Entamoeba histolytica protein kinase, putative 0.034 0.0146 0.1413
Loa Loa (eye worm) hypothetical protein 0.0503 0.0349 0.0471
Onchocerca volvulus 0.0351 0.016 0.0215
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0285 0.0077 0.0077
Schistosoma mansoni serine/threonine protein kinase 0.047 0.0309 0.0759
Echinococcus granulosus casein kinase i 0.0561 0.0422 0.0728
Schistosoma mansoni serine/threonine protein kinase 0.0636 0.0516 0.1268
Schistosoma mansoni protein kinase 0.2086 0.233 0.5725
Brugia malayi Prion-like- 0.0254 0.0038 0.0051
Trypanosoma cruzi polo-like protein kinase, putative 0.0289 0.0082 0.0142
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0371 0.0185 0.1788
Onchocerca volvulus 0.087 0.0808 0.109
Brugia malayi Sex muscle abnormal protein 5 0.0359 0.017 0.0229
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0612 0.0486 0.0837
Loa Loa (eye worm) TK/FER protein kinase 0.0424 0.0251 0.0338
Trichomonas vaginalis CMGC family protein kinase 0.0253 0.0037 0.0332
Echinococcus granulosus cGMP dependent protein kinase 0.0249 0.0031 0.0054
Echinococcus granulosus homeodomain interacting protein kinase 3 0.0316 0.0116 0.02
Loa Loa (eye worm) hypothetical protein 0.0899 0.0845 0.1139
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0836 0.0767 0.1034
Trichomonas vaginalis AGC family protein kinase 0.0658 0.0544 0.4897
Echinococcus granulosus tyrosine protein kinase Src42A 0.0621 0.0498 0.0857
Loa Loa (eye worm) TK/FER protein kinase 0.0424 0.0251 0.0338
Brugia malayi cell division control protein 2 homolog 0.0404 0.0226 0.0304
Loa Loa (eye worm) hypothetical protein 0.0689 0.0582 0.0785
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.4862 0.5804 1
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0671 0.0559 0.0754
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0347 0.0154 0.1386
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.1051 0.1035 0.2544
Schistosoma mansoni serine/threonine protein kinase 0.0275 0.0065 0.0159
Schistosoma mansoni nephrin 0.0756 0.0667 0.1638
Echinococcus multilocularis activin receptor type 0.3647 0.4283 0.4283
Echinococcus multilocularis rac serine:threonine kinase 0.0311 0.011 0.011
Trichomonas vaginalis STE family protein kinase 0.034 0.0146 0.1317
Echinococcus granulosus serine:threonine protein kinase N2 0.1022 0.0999 0.1722
Loa Loa (eye worm) TK/EGFR protein kinase 0.0932 0.0886 0.1194
Schistosoma mansoni tyrosine kinase 0.057 0.0434 0.1066
Echinococcus multilocularis TGF beta receptor type 1 0.0789 0.0708 0.0708
Loa Loa (eye worm) hypothetical protein 0.0254 0.0038 0.0051
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.1295 0.1341 0.1809
Schistosoma mansoni serine/threonine protein kinase 0.0309 0.0108 0.0264
Echinococcus granulosus [G-protein-coupledreceptor] kinase 0.1295 0.1341 0.2311
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0259 0.0044 0.0044
Loa Loa (eye worm) hypothetical protein 0.0547 0.0405 0.0546
Loa Loa (eye worm) hypothetical protein 0.0854 0.0789 0.1064
Schistosoma mansoni serine/threonine protein kinase 0.0364 0.0175 0.0431
Echinococcus granulosus growth factor receptor bound protein 2 0.0374 0.0188 0.0324
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.034 0.0146 0.0146
Trichomonas vaginalis TKL family protein kinase 0.0225 0.0002 0.0021
Toxoplasma gondii AGC kinase 0.0669 0.0558 0.539
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0259 0.0044 0.0076
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0501 0.0347 0.0347
Schistosoma mansoni tyrosine kinase 0.0794 0.0713 0.1753
Loa Loa (eye worm) IKK protein kinase 0.615 0.7416 1
Loa Loa (eye worm) thyroid receptor interactor 0.0729 0.0632 0.0852
Entamoeba histolytica protein kinase, putative 0.0545 0.0402 0.3885
Brugia malayi SH2 domain containing protein 0.0424 0.0251 0.0338
Echinococcus multilocularis slit 2 protein 0.0246 0.0028 0.0028
Entamoeba histolytica protein kinase, putative 0.1047 0.103 0.9948
Loa Loa (eye worm) hypothetical protein 0.0584 0.0452 0.0609
Brugia malayi Protein kinase domain containing protein 0.0391 0.0209 0.0282
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0891 0.0835 0.1126
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0501 0.0347 0.3352
Plasmodium vivax glycogen synthase kinase 3, putative 0.1051 0.1035 1
Trichomonas vaginalis CAMK family protein kinase 0.0289 0.0082 0.0742
Echinococcus multilocularis Immunoglobulin 0.0553 0.0412 0.0412
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0404 0.0226 0.0304
Loa Loa (eye worm) hypothetical protein 0.0308 0.0106 0.0143
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0669 0.0558 0.0961
Schistosoma mansoni growth factor receptor-bound protein 0.0374 0.0188 0.0462
Loa Loa (eye worm) hypothetical protein 0.3932 0.464 0.6257
Trichomonas vaginalis AGC family protein kinase 0.0494 0.0339 0.3053
Loa Loa (eye worm) hypothetical protein 0.1195 0.1215 0.1639
Echinococcus multilocularis cyclin dependent kinase 1 0.0404 0.0226 0.0226
Trichomonas vaginalis CAMK family protein kinase 0.0316 0.0116 0.1043
Echinococcus granulosus dual specificity 0.0253 0.0037 0.0064
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0669 0.0558 0.0961
Echinococcus multilocularis Immunoglobulin 0.0553 0.0412 0.0412
Giardia lamblia Kinase, AGC PKA 0.0271 0.0059 0.053
Schistosoma mansoni serine/threonine-protein kinase 0.0311 0.011 0.027
Trichomonas vaginalis CAMK family protein kinase 0.0316 0.0116 0.1043
Loa Loa (eye worm) TK/INSR protein kinase 0.1232 0.1261 0.1701
Trichomonas vaginalis CAMK family protein kinase 0.0316 0.0116 0.1043
Echinococcus multilocularis casein kinase i 0.0561 0.0422 0.0422
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0545 0.0402 0.3885
Echinococcus multilocularis lachesin 0.0254 0.0038 0.0038
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0501 0.0347 0.3352
Leishmania major protein kinase, putative 0.0928 0.0882 0.152
Schistosoma mansoni serine/threonine protein kinase 0.0316 0.0116 0.0285
Loa Loa (eye worm) SRC-1 0.0989 0.0957 0.1291
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.2568 0.2934 0.3956
Onchocerca volvulus 0.0424 0.0251 0.0338
Schistosoma mansoni serine/threonine protein kinase 0.0351 0.016 0.0392
Loa Loa (eye worm) hypothetical protein 0.132 0.1372 0.185
Echinococcus granulosus neuroglian 0.0285 0.0077 0.0133
Loa Loa (eye worm) hypothetical protein 0.0807 0.073 0.0985
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0494 0.0339 0.0584
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0928 0.0882 0.152
Loa Loa (eye worm) TK/ROR protein kinase 0.0396 0.0215 0.029
Giardia lamblia Kinase, CMGC DYRK 0.0253 0.0037 0.0332
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.025 0.0033 0.0323
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.0391 0.0209 0.0282
Trichomonas vaginalis AGC family protein kinase 0.0658 0.0544 0.4897
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0285 0.0077 0.0077
Brugia malayi Protein kinase domain containing protein 0.0424 0.0251 0.0338
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0561 0.0422 0.0728
Plasmodium falciparum serine/threonine protein kinase, putative 0.0545 0.0402 0.3885

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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