Detailed information for compound 983911

Basic information

Technical information
  • TDR Targets ID: 983911
  • Name: (5aS,7S)-7-[1-(6-aminopurin-9-yl)propan-2-yl] -3-methyl-6,7,8,9-tetrahydro-5aH-pyrano[4,3-b ]chromen-1-one
  • MW: 393.439 | Formula: C21H23N5O3
  • H donors: 1 H acceptors: 4 LogP: 2.2 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC([C@H]1CCC2=Cc3c(O[C@H]2C1)cc(oc3=O)C)Cn1cnc2c1ncnc2N
  • InChi: 1S/C21H23N5O3/c1-11(8-26-10-25-18-19(22)23-9-24-20(18)26)13-3-4-14-6-15-17(29-16(14)7-13)5-12(2)28-21(15)27/h5-6,9-11,13,16H,3-4,7-8H2,1-2H3,(H2,22,23,24)/t11?,13-,16-/m0/s1
  • InChiKey: KLDTZXDMVHXKIB-DKGPUHFJSA-N  


Substructure search Similarity search

Network

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Synonyms

  • (5aS,7S)-7-[2-(6-aminopurin-9-yl)-1-methyl-ethyl]-3-methyl-6,7,8,9-tetrahydro-5aH-pyrano[4,3-b]chromen-1-one
  • (5aS,7S)-7-[2-(6-amino-9-purinyl)-1-methylethyl]-3-methyl-6,7,8,9-tetrahydro-5aH-pyrano[4,3-b]chromen-1-one

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis AGC family protein kinase 0.0423 0.0424 0.3094
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0868 0.1218 0.1493
Giardia lamblia Kinase, CK1 Casein kinase 0.0463 0.0496 0.3631
Onchocerca volvulus 0.0332 0.0261 0.0318
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0228 0.0075 0.0553
Echinococcus granulosus casein kinase I alpha 0.0463 0.0496 0.0632
Loa Loa (eye worm) protein kinase domain-containing protein 0.0304 0.0212 0.026
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.1041 0.1528 0.1873
Loa Loa (eye worm) TK/FER protein kinase 0.0633 0.0798 0.098
Onchocerca volvulus 0.0703 0.0924 0.1132
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0736 0.0983 0.0978
Trichomonas vaginalis CMGC family protein kinase 0.0231 0.008 0.0516
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0599 0.0738 0.0906
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0418 0.0414 0.3491
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0279 0.0166 0.0388
Trichomonas vaginalis CAMK family protein kinase 0.0294 0.0193 0.1359
Brugia malayi casein kinase I 0.0463 0.0496 0.0606
Trichomonas vaginalis CAMK family protein kinase 0.0247 0.011 0.0739
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.1921 0.31 0.3806
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.0294 0.0193 0.0234
Trichomonas vaginalis AGC family protein kinase 0.0455 0.048 0.3514
Schistosoma mansoni protein kinase 0.0676 0.0875 0.216
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0237 0.0091 0.011
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0838 0.1165 0.2886
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0267 0.0145 0.0173
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0423 0.0424 0.054
Loa Loa (eye worm) hypothetical protein 0.2831 0.4724 0.58
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0237 0.0091 0.0085
Onchocerca volvulus 0.024 0.0096 0.0115
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0478 0.0523 0.0517
Entamoeba histolytica PH domain containing protein kinase, putative 0.0636 0.0803 0.6021
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0838 0.1165 0.1431
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0692 0.0904 0.111
Trichomonas vaginalis CAMK family protein kinase 0.0294 0.0193 0.1359
Brugia malayi Protein kinase domain containing protein 0.1052 0.1548 0.1898
Loa Loa (eye worm) hypothetical protein 0.0247 0.011 0.0135
Echinococcus granulosus hypothetical protein 0.0661 0.0848 0.1087
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0226 0.0072 0.0067
Loa Loa (eye worm) hypothetical protein 0.0559 0.0667 0.0819
Brugia malayi Fibronectin type III domain containing protein 0.0486 0.0536 0.0655
Echinococcus multilocularis dual specificity protein kinase clk2 0.0786 0.1073 0.1067
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0458 0.0487 0.0481
Schistosoma mansoni protein kinase 0.0624 0.0782 0.1928
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0736 0.0983 0.0978
Trichomonas vaginalis CAMK family protein kinase 0.0267 0.0145 0.1002
Onchocerca volvulus Basement membrane proteoglycan homolog 0.0218 0.0057 0.0068
Trichomonas vaginalis CMGC family protein kinase 0.0231 0.008 0.0516
Trichomonas vaginalis CMGC family protein kinase 0.0838 0.1165 0.8652
Schistosoma mansoni tyrosine kinase 0.1052 0.1548 0.3842
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0551 0.0651 0.08
Brugia malayi serine/threonine-protein kinase plk-2 0.0267 0.0145 0.0175
Brugia malayi serine/threonine protein kinase 6 0.052 0.0596 0.0729
Schistosoma mansoni protein kinase 0.0303 0.021 0.0496
Onchocerca volvulus 0.0722 0.0958 0.1174
Giardia lamblia Kinase, NEK 0.0228 0.0075 0.0478
Loa Loa (eye worm) hypothetical protein 0.0256 0.0126 0.0155
Schistosoma mansoni tyrosine kinase 0.0317 0.0235 0.0559
Echinococcus granulosus MAP kinase activated protein kinase 2 0.0484 0.0532 0.0679
Schistosoma mansoni protein kinase 0.0303 0.021 0.0496
Brugia malayi protein kinase C II. 0.0549 0.0649 0.0794
Schistosoma mansoni protein kinase 0.1715 0.2732 0.6803
Onchocerca volvulus 0.0693 0.0905 0.1109
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0736 0.0983 0.0978
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0559 0.0667 0.0853
Echinococcus multilocularis casein kinase I alpha 0.0463 0.0496 0.049
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.1551 0.2439 0.2435
Trypanosoma cruzi rac serine-threonine kinase, putative 0.028 0.0167 0.0202
Loa Loa (eye worm) hypothetical protein 0.0382 0.035 0.0429
Echinococcus granulosus hemicentin 1 0.0218 0.0057 0.0066
Schistosoma mansoni ephrin receptor 0.0205 0.0034 0.0057
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0382 0.035 0.0445
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0633 0.0798 0.0793
Trichomonas vaginalis AGC family protein kinase 0.0577 0.0699 0.5154
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.4527 0.7754 1
Echinococcus multilocularis tyrosine protein kinase shark 0.0544 0.0639 0.0634
Echinococcus granulosus cyclin dependent kinase 19 0.1293 0.1978 0.2545
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0604 0.0747 0.0915
Trichomonas vaginalis CMGC family protein kinase 0.0382 0.035 0.2541
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.0347 0.0289 0.0355
Brugia malayi Protein kinase domain containing protein 0.0368 0.0326 0.0397
Entamoeba histolytica hypothetical protein 0.0928 0.1327 1
Onchocerca volvulus Tyrosine kinase homolog 0.2222 0.3637 0.4463
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.0294 0.0193 0.0234
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.052 0.0596 0.4445
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0423 0.0424 0.0419
Echinococcus multilocularis cyclin dependent kinase 1 0.0382 0.035 0.0345
Schistosoma mansoni serine/threonine protein kinase 0.0604 0.0747 0.184
Brugia malayi Cam kinase protein 1 0.0418 0.0414 0.0506
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0486 0.0537 0.1315
Trichomonas vaginalis STE family protein kinase 0.0939 0.1345 1
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0287 0.0181 0.0175
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.4527 0.7754 1
Echinococcus granulosus tyrosine protein kinase Fyn 0.0736 0.0983 0.1262
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0248 0.0111 0.0106
Trichomonas vaginalis CMGC family protein kinase 0.0382 0.035 0.2541
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.1041 0.1528 0.1876
Echinococcus granulosus TGF-beta receptor type-1 0.0624 0.0782 0.1002
Echinococcus multilocularis twitchin 0.027 0.015 0.0144
Giardia lamblia Kinase, AGC PKA 0.0604 0.0747 0.5516
Brugia malayi STE20-like kinase MST 0.0347 0.0289 0.0352
Brugia malayi Protein kinase domain containing protein 0.0928 0.1327 0.1626
Echinococcus multilocularis protein kinase c epsilon type 0.0549 0.0649 0.0643
Loa Loa (eye worm) CAMK/PIM protein kinase 0.1551 0.2439 0.2994
Entamoeba histolytica SH2-protein kinase domain containing protein 0.028 0.0168 0.1194
Brugia malayi protein kinase C3,putative 0.0332 0.0262 0.0319
Echinococcus granulosus neuroglian 0.0602 0.0744 0.0953
Loa Loa (eye worm) hypothetical protein 0.0382 0.035 0.0429
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0736 0.0983 0.0978
Echinococcus multilocularis protein kinase shaggy 0.0838 0.1165 0.116
Echinococcus granulosus tyrosine protein kinase Src42A 0.0736 0.0983 0.1262
Entamoeba histolytica protein kinase domain containing protein 0.0303 0.021 0.1507
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0604 0.0747 0.0957
Entamoeba histolytica protein kinase domain containing protein 0.0838 0.1165 0.8775
Schistosoma mansoni protein kinase C mu 0.0817 0.1127 0.2789
Echinococcus granulosus cyclin dependent kinase 9 0.0338 0.0271 0.0343
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0245 0.0106 0.0101
Onchocerca volvulus 0.0297 0.0199 0.0242
Plasmodium falciparum protein kinase 5 0.0382 0.035 0.2937
Brugia malayi P38 map kinase family protein 2 0.4527 0.7754 0.9519
Entamoeba histolytica protein kinase , putative 0.052 0.0596 0.4445
Trichomonas vaginalis CAMK family protein kinase 0.0294 0.0193 0.1359
Brugia malayi hypothetical protein 0.0425 0.0427 0.0522
Echinococcus granulosus cyclin dependent kinase 0.0382 0.035 0.0445
Plasmodium falciparum glycogen synthase kinase 3 0.0838 0.1165 1
Brugia malayi Doublecortin family protein 0.0242 0.0101 0.0121
Echinococcus multilocularis tyrosine protein kinase Blk 0.0622 0.078 0.0775
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0604 0.0747 0.0957
Echinococcus granulosus cGMP dependent protein kinase 1 0.0226 0.0072 0.0086
Echinococcus granulosus roundabout 2 0.0245 0.0106 0.013
Echinococcus multilocularis activated cdc42 kinase 1 0.1169 0.1756 0.1751
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0838 0.1165 0.1491
Schistosoma mansoni serine/threonine protein kinase 0.0226 0.0072 0.0153
Echinococcus granulosus tyrosine protein kinase Srms 0.0736 0.0983 0.1261
Loa Loa (eye worm) TK/FER protein kinase 0.0332 0.0261 0.032
Schistosoma mansoni tyrosine kinase 0.0736 0.0983 0.2431
Echinococcus granulosus epidermal growth factor receptor 0.0687 0.0896 0.1149
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0418 0.0414 0.0527
Echinococcus multilocularis peroxidasin 0.022 0.0061 0.0055
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0688 0.0896 0.11
Schistosoma mansoni tyrosine kinase 0.0559 0.0667 0.1639
Loa Loa (eye worm) CMGC/CDK/CDK9 protein kinase 0.0306 0.0215 0.0264
Echinococcus multilocularis serine:threonine protein kinase N2 0.0769 0.1042 0.1037
Loa Loa (eye worm) TK/FER protein kinase 0.0332 0.0261 0.032
Trichomonas vaginalis AGC family protein kinase 0.052 0.0596 0.4383
Echinococcus granulosus cyclin dependent kinase 9 0.0306 0.0215 0.027
Loa Loa (eye worm) hypothetical protein 0.0991 0.1439 0.1766
Schistosoma mansoni septate junction protein 0.0218 0.0057 0.0114
Giardia lamblia Kinase, STE STE20 0.0939 0.1345 1
Echinococcus multilocularis neurotracting:lsamp:neurotrimin:obcam 0.0218 0.0057 0.0051
Toxoplasma gondii casein kinase I 0.0463 0.0496 0.4196
Echinococcus multilocularis mitogen activated protein kinase 11 0.4527 0.7754 0.7753
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.196 0.3169 0.3891
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.0486 0.0537 0.0686
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.1062 0.1565 0.156
Loa Loa (eye worm) hypothetical protein 0.0458 0.0487 0.0598
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0218 0.0057 0.0114
Schistosoma mansoni growth factor receptor-bound protein 0.0268 0.0147 0.034
Echinococcus multilocularis roundabout 2 0.0245 0.0106 0.0101
Plasmodium vivax protein kinase Crk2 0.0382 0.035 0.2937
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0463 0.0496 0.0626
Echinococcus multilocularis roundabout 2 0.0245 0.0106 0.0101
Leishmania major protein kinase, putative 0.052 0.0596 0.0755
Trichomonas vaginalis STE family protein kinase 0.0287 0.0181 0.127
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.1009 0.147 0.1805
Echinococcus multilocularis NCK adaptor protein 0.028 0.0168 0.0162
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0418 0.0414 0.3491
Echinococcus multilocularis serine:threonine protein kinase N2 0.0423 0.0424 0.0419
Trichomonas vaginalis CAMK family protein kinase 0.0294 0.0193 0.1359
Entamoeba histolytica protein kinase, putative 0.0423 0.0424 0.3138
Trichomonas vaginalis AGC family protein kinase 0.0577 0.0699 0.5154
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0687 0.0896 0.1149
Echinococcus granulosus serine:threonine protein kinase N2 0.0769 0.1042 0.1338
Brugia malayi Peroxidasin 0.022 0.0061 0.0072
Loa Loa (eye worm) hypothetical protein 0.0676 0.0876 0.1075
Schistosoma mansoni serine/threonine protein kinase 0.0226 0.0072 0.0153
Echinococcus multilocularis STE20 serine:threonine protein kinase 0.0583 0.0709 0.0704
Echinococcus multilocularis TGF beta receptor type 1 0.0624 0.0782 0.0777
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.1503 0.2353 0.2349
Echinococcus granulosus defective proboscis extension response 0.0458 0.0487 0.0621
Trichomonas vaginalis CAMK family protein kinase 0.0267 0.0145 0.1002
Brugia malayi Protein kinase domain containing protein 0.0688 0.0896 0.1098
Brugia malayi Serine/threonine-protein kinase SULU 0.1808 0.2898 0.3556
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0817 0.1127 0.1383
Loa Loa (eye worm) STE/STE20/SLK protein kinase 0.0284 0.0175 0.0215
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0303 0.021 0.0256
Echinococcus multilocularis 0.0195 0.0016 0.0011
Loa Loa (eye worm) CAMK/PIM protein kinase 0.1551 0.2439 0.2994
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.108 0.1597 0.1592
Echinococcus granulosus titin 0.0297 0.0199 0.0249
Schistosoma mansoni tyrosine kinase 0.1401 0.217 0.5399
Onchocerca volvulus 0.0332 0.0261 0.0318
Schistosoma mansoni protein kinase 0.1736 0.277 0.6898
Schistosoma mansoni serine/threonine protein kinase 0.1143 0.1709 0.4247
Schistosoma mansoni serine/threonine protein kinase 0.0379 0.0346 0.0836
Echinococcus granulosus dual specificity 0.0928 0.1327 0.1705
Loa Loa (eye worm) hypothetical protein 0.0418 0.0414 0.0509
Echinococcus granulosus activin receptor type 0.2847 0.4754 0.6128
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0338 0.0273 0.0335
Onchocerca volvulus 0.0332 0.0261 0.0318
Schistosoma mansoni titin 0.0218 0.0057 0.0114
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0382 0.035 0.2937
Schistosoma mansoni vav2 0.031 0.0222 0.0528
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0279 0.0166 0.0208
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0332 0.0261 0.1898
Leishmania major mitogen-activated protein kinase kinase 5, putative;with=GeneDB:LmxM36.0860 0.0939 0.1345 0.1723
Schistosoma mansoni vesicular amine transporter 0.0458 0.0487 0.1189
Echinococcus multilocularis protein tyrosine kinase 0.2431 0.401 0.4006
Echinococcus granulosus dual specificity 0.0231 0.008 0.0096
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0268 0.0147 0.0181
Echinococcus granulosus casein kinase I delta 0.0463 0.0496 0.0632
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0604 0.0747 0.0742
Trypanosoma cruzi Protein kinase B 0.028 0.0167 0.0202
Echinococcus granulosus N chimaerin 0.0279 0.0166 0.0208
Trichomonas vaginalis CMGC family protein kinase 0.0231 0.008 0.0516
Entamoeba histolytica protein kinase, putative 0.0231 0.008 0.0523
Schistosoma mansoni tyrosine kinase 0.0736 0.0983 0.2431
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.0231 0.008 0.0089
Brugia malayi SRC-1 0.0736 0.0983 0.1205
Schistosoma mansoni serine/threonine protein kinase 0.0382 0.035 0.0848
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0245 0.0106 0.013
Loa Loa (eye worm) hypothetical protein 0.0197 0.0019 0.0024
Brugia malayi Protein kinase domain containing protein 0.4746 0.8145 1
Echinococcus granulosus Immunoglobulin 0.0458 0.0487 0.0621
Loa Loa (eye worm) IKK protein kinase 0.4746 0.8145 1
Loa Loa (eye worm) hypothetical protein 0.0604 0.0747 0.0917
Echinococcus granulosus protein kinase c iota type 0.063 0.0793 0.1017
Trypanosoma brucei cdc2-related kinase 1 0.0382 0.035 0.0438
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.0339 0.0274 0.0336
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0736 0.0983 0.0978
Echinococcus multilocularis serine:threonine protein kinase 38 0.0423 0.0424 0.0419
Giardia lamblia Kinase, CMGC GSK 0.0838 0.1165 0.8652
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.0247 0.011 0.0135
Loa Loa (eye worm) hypothetical protein 0.0332 0.0261 0.032
Schistosoma mansoni tyrosine kinase 0.051 0.0579 0.142
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0321 0.0242 0.0237
Schistosoma mansoni serine/threonine protein kinase 0.0256 0.0125 0.0283
Brugia malayi SH2 domain containing protein 0.0332 0.0261 0.0318
Echinococcus granulosus casein kinase I alpha 0.0463 0.0496 0.0632
Brugia malayi serine/threonine kinase 12 0.052 0.0596 0.0729
Brugia malayi ribosomal protein S6 kinase alpha 3 0.0711 0.0938 0.115
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0248 0.0111 0.0136
Entamoeba histolytica protein kinase, putative 0.0928 0.1327 1
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0604 0.0747 0.0742
Trichomonas vaginalis STE family protein kinase 0.0266 0.0142 0.0983
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0928 0.1327 0.1699
Schistosoma mansoni titin 0.0297 0.0199 0.0469
Loa Loa (eye worm) hypothetical protein 0.0691 0.0902 0.1108
Entamoeba histolytica protein kinase, putative 0.0287 0.0181 0.1288
Schistosoma mansoni serine/threonine protein kinase 0.0588 0.0719 0.177
Plasmodium falciparum NIMA related kinase 1 0.0228 0.0075 0.0553
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0279 0.0166 0.0388
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0604 0.0747 0.6376
Loa Loa (eye worm) TK/KIN16 protein kinase 0.261 0.433 0.5316
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0785 0.107 0.1065
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0245 0.0106 0.0101
Echinococcus granulosus Vam6:Vps39 protein 0.0486 0.0537 0.0686
Brugia malayi Protein kinase domain containing protein 0.1169 0.1756 0.2153
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.4527 0.7754 0.9519
Giardia lamblia Kinase, AGC AKT 0.0711 0.0938 0.6949
Brugia malayi bone morphogenetic protein type 1 receptor 0.0676 0.0875 0.1072
Trypanosoma brucei mitogen-activated protein kinase kinase 5 0.0939 0.1345 0.1723
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.1808 0.2898 0.3558
Entamoeba histolytica protein kinase, putative 0.0418 0.0414 0.3064
Echinococcus multilocularis titin 0.0297 0.0199 0.0193
Schistosoma mansoni serine/threonine protein kinase 0.0267 0.0145 0.0334
Echinococcus multilocularis cyclin dependent kinase 1 0.0382 0.035 0.0345
Loa Loa (eye worm) TK/INSR protein kinase 0.1052 0.1548 0.19
Entamoeba histolytica protein kinase, putative 0.052 0.0596 0.4445
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.0231 0.008 0.0098
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0423 0.0424 0.0521
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0418 0.0414 0.0409
Trichomonas vaginalis AGC family protein kinase 0.0577 0.0699 0.5154
Echinococcus multilocularis casein kinase ii subunit alpha 0.0192 0.0011 0.0006
Onchocerca volvulus 0.0577 0.0699 0.0856
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0604 0.0747 0.0742
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0267 0.0145 0.0139
Brugia malayi Variant SH3 domain containing protein 0.0279 0.0166 0.0202
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0325 0.0249 0.2061
Schistosoma mansoni serine/threonine protein kinase 0.0418 0.0414 0.1008
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.1551 0.2439 0.2993
Schistosoma mansoni tyrosine kinase 0.0544 0.0639 0.1569
Echinococcus multilocularis raf serine:threonine protein kinase 0.0302 0.0208 0.0202
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0928 0.1327 0.1699
Echinococcus granulosus protein kinase c epsilon type 0.0549 0.0649 0.083
Schistosoma mansoni serine/threonine protein kinase 0.0431 0.0438 0.1068
Echinococcus granulosus casein kinase I delta 0.0463 0.0496 0.0632
Toxoplasma gondii histone kinase SNF1, putative 0.0294 0.0193 0.1571
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.052 0.0596 0.4445
Loa Loa (eye worm) TKL/STKR/TYPE2 protein kinase 0.0551 0.0651 0.08
Schistosoma mansoni serine/threonine protein kinase 0.0434 0.0443 0.108
Entamoeba histolytica protein kinase 2, putative 0.0248 0.0111 0.0761
Schistosoma mansoni tyrosine kinase 0.0825 0.1142 0.2827
Echinococcus multilocularis beta adrenergic receptor kinase 0.0227 0.0074 0.0069
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0486 0.0537 0.0679
Leishmania major protein kinase, putative 0.0786 0.1073 0.1371
Schistosoma mansoni tyrosine kinase 0.0687 0.0896 0.2213
Entamoeba histolytica protein kinase, putative 0.0838 0.1165 0.8775
Echinococcus multilocularis tyrosine protein kinase Abl 0.0917 0.1307 0.1302
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0604 0.0747 0.095
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0838 0.1165 0.1491
Entamoeba histolytica protein kinase, putative 0.0266 0.0142 0.0997
Brugia malayi Immunoglobulin I-set domain containing protein 0.0218 0.0057 0.0067
Loa Loa (eye worm) hypothetical protein 0.0425 0.0427 0.0524
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0294 0.0193 0.0234
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0928 0.1327 0.1699
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0303 0.021 0.0256
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0736 0.0983 0.1262
Echinococcus granulosus dual specificity mitogen activated protein 0.0939 0.1345 0.1729
Echinococcus granulosus tyrosine protein kinase HCK 0.0468 0.0504 0.0643
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0303 0.021 0.0263
Loa Loa (eye worm) TK protein kinase 0.0478 0.0522 0.0641
Trypanosoma brucei casein kinase I, isoform 2 0.0463 0.0496 0.0626
Leishmania major protein kinase A catalytic subunit isoform 2 0.0604 0.0747 0.095
Schistosoma mansoni adapter molecule crk 0.0268 0.0147 0.034
Schistosoma mansoni serine/threonine protein kinase 0.0231 0.008 0.0172
Loa Loa (eye worm) hypothetical protein 0.0693 0.0905 0.1112
Onchocerca volvulus 0.0338 0.0271 0.0331
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0294 0.0193 0.0237
Echinococcus multilocularis maternal embryonic leucine zipper kinase 0.0207 0.0038 0.0032
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.1736 0.277 0.3567
Echinococcus granulosus protein kinase 0.0662 0.085 0.109
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0218 0.0057 0.007
Echinococcus multilocularis protein kinase c iota type 0.063 0.0793 0.0788
Schistosoma mansoni protein kinase 0.052 0.0596 0.1462
Trypanosoma cruzi casein kinase, putative 0.0463 0.0496 0.0626
Echinococcus granulosus insulin receptor 0.1052 0.1548 0.199
Plasmodium falciparum cGMP-dependent protein kinase 0.0226 0.0072 0.0529
Schistosoma mansoni serine/threonine protein kinase 0.0258 0.0128 0.0293
Loa Loa (eye worm) TK/EPH protein kinase 0.0258 0.0129 0.0159
Echinococcus granulosus serine:threonine protein kinase 3 0.0347 0.0289 0.0365
Loa Loa (eye worm) AGC/PKG protein kinase 0.0226 0.0072 0.0089
Giardia lamblia Kinase, AGC PKA 0.0248 0.0111 0.075
Schistosoma mansoni serine/threonine protein kinase 0.0304 0.0212 0.0501
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0418 0.0414 0.052
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0287 0.0181 0.0226
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0303 0.021 0.0204
Trichomonas vaginalis STE family protein kinase 0.0287 0.0181 0.127
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.052 0.0596 0.4445
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0786 0.1073 0.1371
Brugia malayi Protein kinase c protein 2 0.0291 0.0187 0.0227
Loa Loa (eye worm) TK/FER protein kinase 0.0332 0.0261 0.032
Brugia malayi protein unc-22 0.0297 0.0199 0.0241
Echinococcus granulosus rho-associated protein kinase 1 0.0703 0.0924 0.1185
Schistosoma mansoni cell adhesion molecule 0.056 0.0668 0.1642
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.0484 0.0532 0.0653
Onchocerca volvulus 0.0224 0.0068 0.0082
Onchocerca volvulus 0.0332 0.0261 0.0318
Schistosoma mansoni serine/threonine protein kinase 0.0294 0.0193 0.0453
Onchocerca volvulus 0.0691 0.0902 0.1105
Schistosoma mansoni tyrosine kinase 0.0687 0.0896 0.2213
Brugia malayi Protein kinase domain containing protein 0.0607 0.0752 0.0921
Trypanosoma brucei protein kinase, putative 0.0303 0.021 0.0256
Entamoeba histolytica protein kinase, putative 0.0297 0.0198 0.1422
Echinococcus multilocularis ephrin type A receptor 4 A 0.0241 0.0098 0.0093
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0458 0.0487 0.1189
Echinococcus multilocularis Immunoglobulin 0.0458 0.0487 0.0481
Trypanosoma cruzi cdc2-related kinase 3 0.0382 0.035 0.0438
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0382 0.035 0.043
Echinococcus multilocularis c Jun NH2 terminal kinase 0.196 0.3169 0.3165
Schistosoma mansoni hypothetical protein 0.0486 0.0537 0.1315
Plasmodium vivax protein kinase, putative 0.0192 0.0012 0.0004
Schistosoma mansoni protein kinase 0.0287 0.0181 0.0424
Brugia malayi Immunoglobulin I-set domain containing protein 0.0245 0.0106 0.0128
Schistosoma mansoni tyrosine kinase 0.051 0.0579 0.142
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0868 0.1218 0.1565
Schistosoma mansoni protein kinase 0.0284 0.0175 0.041
Brugia malayi Protein kinase domain containing protein 0.036 0.0312 0.038
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0604 0.0747 0.0957
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0248 0.0111 0.0129
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0604 0.0747 0.0742
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0418 0.0414 0.3491
Echinococcus multilocularis cyclin dependent kinase 7 0.0434 0.0443 0.0438
Echinococcus granulosus contactin 0.0245 0.0106 0.013
Echinococcus granulosus cyclin dependent kinase 5 0.0382 0.035 0.0445
Loa Loa (eye worm) AUR protein kinase 0.052 0.0596 0.0732
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0588 0.0719 0.0714
Plasmodium falciparum calcium-dependent protein kinase 4 0.0418 0.0414 0.3491
Trypanosoma brucei protein kinase, putative 0.0838 0.1165 0.1491
Brugia malayi cell division control protein 2 homolog 0.0382 0.035 0.0428
Giardia lamblia Kinase, NEK 0.0228 0.0075 0.0478
Loa Loa (eye worm) hypothetical protein 0.0218 0.0057 0.007
Loa Loa (eye worm) hypothetical protein 0.0817 0.1128 0.1385
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0786 0.1073 0.1371
Schistosoma mansoni tyrosine kinase 0.0389 0.0363 0.0879
Echinococcus multilocularis leucine rich repeat serine:threonine protein 0.036 0.0312 0.0306
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0287 0.0181 0.0175
Echinococcus granulosus cyclin dependent kinase 1 0.0382 0.035 0.0445
Brugia malayi Protein kinase domain containing protein 0.0332 0.0261 0.0318
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0604 0.0747 0.095
Loa Loa (eye worm) TK/ALK protein kinase 0.3205 0.5393 0.662
Echinococcus granulosus NDR protein kinase 0.0423 0.0424 0.054
Giardia lamblia Kinase, CMGC GSK 0.0838 0.1165 0.8652
Schistosoma mansoni serine/threonine protein kinase 0.0306 0.0215 0.0509
Loa Loa (eye worm) SRC-1 0.0736 0.0983 0.1207
Entamoeba histolytica protein kinase domain containing protein 0.0306 0.0215 0.1548
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0294 0.0193 0.0234
Entamoeba histolytica serine/threonine protein kinase, putative 0.0267 0.0145 0.1016
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0423 0.0424 0.0419
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0248 0.0111 0.0867
Onchocerca volvulus 0.0332 0.0261 0.0318
Brugia malayi Protein kinase domain containing protein 0.0577 0.0699 0.0856
Leishmania major protein kinase, putative 0.0303 0.021 0.0256
Trichomonas vaginalis CAMK family protein kinase 0.0294 0.0193 0.1359
Schistosoma mansoni serine/threonine protein kinase 0.0604 0.0747 0.184
Loa Loa (eye worm) hypothetical protein 0.0688 0.0896 0.11
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0418 0.0414 0.0409
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.0231 0.008 0.0596
Brugia malayi protein C17H12.11 0.0425 0.0427 0.0522
Trypanosoma cruzi casein kinase, putative 0.0463 0.0496 0.0626
Brugia malayi Protein kinase domain containing protein 0.0292 0.019 0.023
Trichomonas vaginalis AGC family protein kinase 0.0604 0.0747 0.5516
Entamoeba histolytica cell division protein kinase 2, putative 0.0414 0.0407 0.3007
Loa Loa (eye worm) hypothetical protein 0.0722 0.0958 0.1176
Trypanosoma brucei rac serine-threonine kinase, putative 0.0577 0.0699 0.0888
Plasmodium falciparum calcium-dependent protein kinase 2 0.0418 0.0414 0.3491
Entamoeba histolytica PH domain containing protein kinase, putative 0.0636 0.0803 0.6021
Trichomonas vaginalis STE family protein kinase 0.0228 0.0075 0.0478
Brugia malayi serine/threonine-protein kinase 6 0.052 0.0596 0.0729
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0418 0.0414 0.0509
Loa Loa (eye worm) hypothetical protein 0.0566 0.068 0.0834
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0418 0.0414 0.0409
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0604 0.0747 0.6376
Trypanosoma cruzi cdc2-related kinase 1 0.0382 0.035 0.0438
Trichomonas vaginalis CK1 family protein kinase 0.0463 0.0496 0.3631
Plasmodium vivax casein kinase 1, putative 0.0463 0.0496 0.4196
Echinococcus granulosus phosphorylase kinase gamma subunit 0.0256 0.0125 0.0154
Giardia lamblia Kinase, CAMK CAMKL 0.0325 0.0249 0.1783
Trichomonas vaginalis CAMK family protein kinase 0.0294 0.0193 0.1359
Trichomonas vaginalis CK1 family protein kinase 0.0463 0.0496 0.3631
Brugia malayi casein kinase 1, delta 0.0463 0.0496 0.0606
Schistosoma mansoni tyrosine kinase 0.051 0.0579 0.142
Echinococcus multilocularis phosphorylase kinase gamma subunit 0.0256 0.0125 0.0119
Loa Loa (eye worm) hypothetical protein 0.0486 0.0536 0.0658
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0612 0.0762 0.0975
Schistosoma mansoni serine/threonine protein kinase 0.0588 0.0719 0.177
Loa Loa (eye worm) TKL/LRRK protein kinase 0.036 0.0312 0.0383
Trichomonas vaginalis CAMK family protein kinase 0.0294 0.0193 0.1359
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.0484 0.0532 0.0527
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0418 0.0414 0.0506
Loa Loa (eye worm) hypothetical protein 0.0566 0.068 0.0834
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.1143 0.1709 0.2097
Echinococcus multilocularis tyrosine protein kinase otk 0.0218 0.0057 0.0051
Schistosoma mansoni serine/threonine protein kinase 0.0868 0.1218 0.3018
Schistosoma mansoni serine/threonine protein kinase 0.1009 0.147 0.3648
Brugia malayi Protein kinase domain containing protein 0.0332 0.0261 0.0318
Loa Loa (eye worm) hypothetical protein 0.0676 0.0876 0.1075
Echinococcus multilocularis transfer RNA-Thr 0.1169 0.1756 0.1751
Schistosoma mansoni serine/threonine protein kinase 0.0604 0.0747 0.184
Loa Loa (eye worm) hypothetical protein 0.0429 0.0435 0.0534
Trichomonas vaginalis CK1 family protein kinase 0.0463 0.0496 0.3631
Echinococcus multilocularis casein kinase i 0.0463 0.0496 0.049
Schistosoma mansoni protein kinase 0.1736 0.277 0.6898
Trichomonas vaginalis CAMK family protein kinase 0.0294 0.0193 0.1359
Echinococcus multilocularis epidermal growth factor receptor 0.0825 0.1142 0.1137
Schistosoma mansoni serine/threonine protein kinase 0.0463 0.0496 0.1211
Loa Loa (eye worm) hypothetical protein 0.0294 0.0193 0.0237
Trypanosoma cruzi cdc2-related kinase 3 0.0382 0.035 0.0438
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0298 0.02 0.1411
Trypanosoma brucei cdc2-related kinase 3 0.0382 0.035 0.0438
Trichomonas vaginalis CAMK family protein kinase 0.0294 0.0193 0.1359
Entamoeba histolytica protein kinase, putative 0.0577 0.0699 0.5228
Brugia malayi Prion-like- 0.0218 0.0057 0.0067
Brugia malayi intracellular kinase 0.0838 0.1165 0.1428
Echinococcus granulosus casein kinase i 0.0463 0.0496 0.0632
Brugia malayi Protein kinase domain containing protein 0.0304 0.0212 0.0257
Schistosoma mansoni tyrosine kinase 0.1052 0.1548 0.3842
Loa Loa (eye worm) TK/FER protein kinase 0.0332 0.0261 0.032
Echinococcus granulosus TGF beta receptor type 1 0.0624 0.0782 0.1002
Loa Loa (eye worm) hypothetical protein 0.0486 0.0536 0.0658
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0463 0.0496 0.0609
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0245 0.0106 0.0237
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0382 0.035 0.043
Echinococcus granulosus tyrosine protein kinase Src64B 0.0736 0.0983 0.1262
Loa Loa (eye worm) hypothetical protein 0.0803 0.1102 0.1353
Schistosoma mansoni serine/threonine protein kinase 0.0928 0.1327 0.3289
Loa Loa (eye worm) hypothetical protein 0.0661 0.0848 0.1041
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0423 0.0424 0.054
Echinococcus multilocularis cyclin dependent kinase 5 0.0382 0.035 0.0345
Entamoeba histolytica protein kinase, putative 0.028 0.0168 0.1194
Brugia malayi Protein kinase domain containing protein 0.0247 0.011 0.0132
Trichomonas vaginalis CAMK family protein kinase 0.0207 0.0038 0.0199
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0379 0.0346 0.034
Entamoeba histolytica protein kinase, putative 0.0577 0.0699 0.5228
Loa Loa (eye worm) hypothetical protein 0.0486 0.0536 0.0658
Echinococcus multilocularis homeodomain interacting protein kinase 3 0.0294 0.0193 0.0187
Echinococcus granulosus tyrosine kinase 0.0332 0.0261 0.033
Schistosoma mansoni tyrosine kinase 0.2431 0.401 1
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0205 0.0035 0.0043
Brugia malayi probable protein kinase 0.1148 0.1719 0.2108
Schistosoma mansoni protein kinase 0.1736 0.277 0.6898
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0418 0.0414 0.0527
Echinococcus granulosus tyrosine kinase 0.0622 0.078 0.0999
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.0537 0.0628 0.0771
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.1062 0.1565 0.2012
Brugia malayi Immunoglobulin I-set domain containing protein 0.0218 0.0057 0.0067
Entamoeba histolytica PH domain containing protein kinase, putative 0.028 0.0167 0.1186
Entamoeba histolytica protein kinase domain containing protein 0.021 0.0043 0.0241
Entamoeba histolytica PH domain containing protein kinase, putative 0.028 0.0167 0.1186
Brugia malayi hypothetical protein 0.0332 0.0261 0.0318
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0486 0.0537 0.1315
Schistosoma mansoni serine/threonine protein kinase 0.027 0.015 0.0346
Echinococcus granulosus NCK adaptor protein 0.0268 0.0147 0.0183
Onchocerca volvulus 0.4746 0.8145 1
Loa Loa (eye worm) AUR protein kinase 0.052 0.0596 0.0732
Entamoeba histolytica protein kinase, putative 0.0297 0.0198 0.1422
Loa Loa (eye worm) hypothetical protein 0.0268 0.0147 0.0181
Schistosoma mansoni growth factor receptor-bound protein 0.028 0.0168 0.0392
Trichomonas vaginalis CAMK family protein kinase 0.0294 0.0193 0.1359
Loa Loa (eye worm) hypothetical protein 0.0458 0.0487 0.0598
Trichomonas vaginalis CAMK family protein kinase 0.0294 0.0193 0.1359
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.3884 0.6606 0.8519
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0549 0.0649 0.0797
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.1551 0.2439 0.3141
Trypanosoma cruzi mitogen-activated protein kinase kinase 5 0.0939 0.1345 0.1723
Echinococcus multilocularis serine:threonine protein kinase 0.0247 0.011 0.0104
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0786 0.1073 0.1317
Loa Loa (eye worm) camk/dcamkl protein kinase 0.0242 0.0101 0.0124
Brugia malayi Protein kinase domain containing protein 0.0256 0.0125 0.015
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0292 0.019 0.0233
Echinococcus multilocularis Immunoglobulin 0.0458 0.0487 0.0481
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0868 0.1218 0.1496
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0267 0.0145 0.018
Brugia malayi Hr1 repeat family protein 0.1193 0.1798 0.2205
Entamoeba histolytica protein kinase domain containing protein 0.0838 0.1165 0.8775
Brugia malayi Serine/threonine-protein kinase Pim-3 0.1551 0.2439 0.2993
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0688 0.0896 0.11
Loa Loa (eye worm) gastrulation defective protein 1 0.1168 0.1754 0.2153
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.1736 0.277 0.2765
Brugia malayi Temporarily assigned gene name protein 59 0.0486 0.0537 0.0657
Giardia lamblia Kinase, CMGC CLK 0.0786 0.1073 0.7955
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0463 0.0496 0.0609
Schistosoma mansoni tyrosine kinase 0.1062 0.1565 0.3885
Brugia malayi Protein kinase domain containing protein 0.1921 0.31 0.3804
Brugia malayi Immunoglobulin I-set domain containing protein 0.0218 0.0057 0.0067
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0633 0.0798 0.1023
Brugia malayi hypothetical protein 0.0486 0.0537 0.0657
Echinococcus granulosus mitogen activated protein kinase 14 0.4527 0.7754 1
Echinococcus granulosus tyrosine protein kinase Src42A 0.0457 0.0484 0.0617
Entamoeba histolytica protein kinase domain containing protein 0.052 0.0596 0.4445
Brugia malayi Protein kinase domain containing protein 0.0339 0.0274 0.0333
Echinococcus granulosus activated cdc42 kinase 1 0.1169 0.1756 0.2258
Echinococcus multilocularis mitogen activated protein kinase 14 0.4527 0.7754 0.7753
Schistosoma mansoni serine/threonine protein kinase 0.0785 0.107 0.2647
Loa Loa (eye worm) TK protein kinase 0.1206 0.1822 0.2237
Loa Loa (eye worm) hypothetical protein 0.0455 0.0481 0.0591
Brugia malayi Protein kinase domain containing protein 0.1715 0.2732 0.3352
Echinococcus granulosus serine:threonine kinase SAD 1 0.0294 0.0193 0.0241
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0287 0.0181 0.0175
Schistosoma mansoni serine/threonine protein kinase 0.0484 0.0532 0.1302
Echinococcus multilocularis casein kinase I gamma 0.0304 0.0212 0.0206
Giardia lamblia Kinase, CAMK CAMKL 0.0325 0.0249 0.1783
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0532 0.0619 0.0791
Trichomonas vaginalis STE family protein kinase 0.0939 0.1345 1
Schistosoma mansoni serine/threonine protein kinase 0.0302 0.0208 0.0491
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0458 0.0487 0.1189
Schistosoma mansoni protein kinase 0.0266 0.0142 0.0328
Giardia lamblia Kinase, CMGC CDK 0.0382 0.035 0.2541
Entamoeba histolytica serine/threonine protein kinase, putative 0.0294 0.0193 0.1379
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.1319 0.2023 0.2484
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0268 0.0147 0.034
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.1456 0.2269 0.2921
Brugia malayi Casein kinase II, alpha chain 0.0192 0.0011 0.0011
Echinococcus granulosus tyrosine protein kinase Fyn 0.0736 0.0983 0.1262
Toxoplasma gondii AGC kinase 0.0604 0.0747 0.6376
Echinococcus granulosus leucine rich repeat serine:threonine protein 0.036 0.0311 0.0394
Trichomonas vaginalis CAMK family protein kinase 0.0294 0.0193 0.1359
Brugia malayi protein-tyrosine kinase 0.0622 0.078 0.0955
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0736 0.0983 0.0978
Loa Loa (eye worm) TK/FER protein kinase 0.0332 0.0261 0.032
Schistosoma mansoni serine/threonine protein kinase 0.1229 0.1863 0.463
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.1319 0.2023 0.2482
Schistosoma mansoni serine/threonine protein kinase 0.0292 0.019 0.0446
Schistosoma mansoni serine/threonine protein kinase 0.0297 0.0199 0.0469
Plasmodium vivax glycogen synthase kinase 3, putative 0.0838 0.1165 1
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0218 0.0057 0.007
Plasmodium falciparum calcium-dependent protein kinase 5 0.0418 0.0414 0.3491
Echinococcus multilocularis serine:threonine protein kinase 3 0.0347 0.0289 0.0283
Schistosoma mansoni serine/threonine kinase 0.0423 0.0424 0.1032
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0928 0.1327 0.1699
Loa Loa (eye worm) CAMK protein kinase 0.0297 0.0199 0.0244
Echinococcus multilocularis tyrosine protein kinase Srms 0.0622 0.078 0.0775
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0333 0.0263 0.0323
Trichomonas vaginalis CMGC family protein kinase 0.0231 0.008 0.0516
Trichomonas vaginalis CMGC family protein kinase 0.0231 0.008 0.0516
Brugia malayi Protein kinase domain containing protein 0.3206 0.5394 0.6622
Echinococcus granulosus dual specificity protein kinase clk2 0.0786 0.1073 0.1377
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0736 0.0983 0.1262
Brugia malayi C1-like domain containing protein 0.0817 0.1127 0.1381
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.052 0.0596 0.0591
Trichomonas vaginalis CAMK family protein kinase 0.0294 0.0193 0.1359
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0604 0.0747 0.6376
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0418 0.0414 0.0527
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.1596 0.2519 0.3092
Echinococcus granulosus tyrosine protein kinase otk 0.0218 0.0057 0.0066
Echinococcus multilocularis neuroglian 0.0245 0.0106 0.0101
Brugia malayi cyclin-dependent kinase 7 homolog 0.0466 0.05 0.0611
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.0231 0.008 0.0096
Echinococcus multilocularis hemicentin 1 0.0218 0.0057 0.0051
Echinococcus granulosus fibroblast growth factor receptor 4 0.1062 0.1565 0.2012
Loa Loa (eye worm) hypothetical protein 0.0486 0.0537 0.0659
Loa Loa (eye worm) hypothetical protein 0.0486 0.0537 0.0659
Loa Loa (eye worm) hypothetical protein 0.0197 0.0019 0.0024
Brugia malayi Protein kinase domain containing protein 0.0332 0.0261 0.0318
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0418 0.0414 0.3491
Leishmania major protein kinase, putative 0.0418 0.0414 0.052
Schistosoma mansoni serine/threonine protein kinase 0.0785 0.107 0.2647
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0227 0.0074 0.0091
Schistosoma mansoni protein kinase 0.1148 0.1719 0.4271
Echinococcus multilocularis neuroglian 0.0602 0.0744 0.0739
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0228 0.0075 0.0553
Brugia malayi Protein kinase domain containing protein 0.1551 0.2439 0.2993
Trichomonas vaginalis CAMK family protein kinase 0.0294 0.0193 0.1359
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0928 0.1327 0.1629
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0379 0.0346 0.034
Loa Loa (eye worm) hypothetical protein 0.0457 0.0485 0.0595
Trichomonas vaginalis CMGC family protein kinase 0.0838 0.1165 0.8652
Loa Loa (eye worm) hypothetical protein 0.022 0.0061 0.0075
Schistosoma mansoni serine/threonine protein kinase 0.0382 0.035 0.0848
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0446 0.0464 0.1133
Schistosoma mansoni ste20-related kinase 0.0296 0.0197 0.0465
Echinococcus granulosus tyrosine protein kinase Fyn 0.0736 0.0983 0.1262
Trypanosoma brucei SNF1-related protein kinases, putative 0.0294 0.0193 0.0234
Giardia lamblia Kinase, CMGC CDK 0.0382 0.035 0.2541
Echinococcus granulosus roundabout 2 0.0704 0.0925 0.1186
Brugia malayi Immunoglobulin I-set domain containing protein 0.261 0.433 0.5314
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0457 0.0484 0.0478
Plasmodium falciparum calcium-dependent protein kinase 1 0.0418 0.0414 0.3491
Trichomonas vaginalis CAMK family protein kinase 0.0267 0.0145 0.1002
Echinococcus multilocularis tyrosine protein kinase ABL1 0.1565 0.2464 0.246
Trichomonas vaginalis CAMK family protein kinase 0.0267 0.0145 0.1002
Brugia malayi Protein kinase domain containing protein 0.0423 0.0424 0.0518
Echinococcus granulosus mitogen activated protein kinase 11 0.4527 0.7754 1
Echinococcus multilocularis casein kinase I alpha 0.0463 0.0496 0.049
Brugia malayi Protein kinase domain containing protein 0.0551 0.0651 0.0797
Loa Loa (eye worm) CMGC/CDK/CDK7 protein kinase 0.0434 0.0443 0.0544
Echinococcus granulosus twitchin 0.0728 0.0968 0.1242
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0612 0.0762 0.0756
Trichomonas vaginalis STE family protein kinase 0.0939 0.1345 1
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.1143 0.1709 0.2099
Echinococcus multilocularis 0.0661 0.0848 0.0843
Trichomonas vaginalis AGC family protein kinase 0.0205 0.0035 0.0177
Schistosoma mansoni serine/threonine protein kinase 0.0258 0.0128 0.0293
Trichomonas vaginalis AGC family protein kinase 0.0577 0.0699 0.5154
Echinococcus granulosus growth factor receptor bound protein 2 0.028 0.0168 0.0209
Loa Loa (eye worm) hypothetical protein 0.0218 0.0057 0.007
Loa Loa (eye worm) AGC/PKA protein kinase 0.0604 0.0747 0.0917
Entamoeba histolytica casein kinase 1, putative 0.0463 0.0496 0.3683
Echinococcus multilocularis expressed conserved protein 0.0226 0.0072 0.0067
Echinococcus granulosus protein kinase shaggy 0.0838 0.1165 0.1497
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0303 0.021 0.0256
Echinococcus granulosus beta-adrenergic receptor kinase 0.0227 0.0074 0.0088
Loa Loa (eye worm) TK protein kinase 0.0468 0.0504 0.0619
Brugia malayi hypothetical protein 0.0197 0.0019 0.0021
Trypanosoma cruzi cdc2-related kinase 1 0.0382 0.035 0.0438
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0786 0.1073 0.1371
Trypanosoma cruzi aurora B kinase, putative 0.052 0.0596 0.0755
Echinococcus granulosus serine:threonine protein kinase TAO1 0.1808 0.2898 0.3733
Echinococcus multilocularis insulin receptor 0.1052 0.1548 0.1543
Trichomonas vaginalis CAMK family protein kinase 0.0299 0.0202 0.1425
Brugia malayi Furin-like cysteine rich region family protein 0.0825 0.1142 0.1399
Onchocerca volvulus 0.0463 0.0496 0.0606
Echinococcus granulosus serine:threonine protein kinase 0.0247 0.011 0.0135
Schistosoma mansoni tyrosine kinase 0.0446 0.0464 0.1133
Brugia malayi SH2 domain containing protein 0.0633 0.0798 0.0977
Loa Loa (eye worm) hypothetical protein 0.0461 0.0491 0.0603
Trichomonas vaginalis CAMK family protein kinase 0.0418 0.0414 0.302
Brugia malayi serine/threonine-protein kinase PAK 7 0.1596 0.2519 0.3091
Loa Loa (eye worm) TK/ROR protein kinase 0.0321 0.0242 0.0297
Echinococcus multilocularis serine:threonine protein kinase 0.0247 0.011 0.0104
Schistosoma mansoni hypothetical protein 0.0197 0.0019 0.002
Schistosoma mansoni serine/threonine-protein kinase 0.028 0.0167 0.039
Schistosoma mansoni serine/threonine protein kinase 0.0227 0.0074 0.0157
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0192 0.0011 0.0014
Echinococcus granulosus neuroglian 0.0245 0.0106 0.013
Echinococcus granulosus tyrosine protein kinase Btk29A 0.1503 0.2353 0.303
Echinococcus granulosus protein kinase C gamma type 0.0464 0.0496 0.0633
Loa Loa (eye worm) hypothetical protein 0.1116 0.1661 0.204
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0736 0.0983 0.0978
Trichomonas vaginalis AGC family protein kinase 0.0577 0.0699 0.5154
Loa Loa (eye worm) CMGC/CDK/CDK8 protein kinase 0.1293 0.1978 0.2428
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0736 0.0983 0.0978
Loa Loa (eye worm) AUR protein kinase 0.052 0.0596 0.0732
Loa Loa (eye worm) hypothetical protein 0.1023 0.1495 0.1835
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0279 0.0166 0.0161
Schistosoma mansoni nephrin 0.063 0.0793 0.1955
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0418 0.0414 0.3491
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0226 0.0072 0.0067
Brugia malayi Tyrosine-protein kinase abl-1 0.0762 0.1029 0.1261
Loa Loa (eye worm) AGC/AKT protein kinase 0.0577 0.0699 0.0858
Trichomonas vaginalis CAMK family protein kinase 0.0294 0.0193 0.1359
Echinococcus multilocularis hemicentin 1 0.0218 0.0057 0.0051
Entamoeba histolytica protein kinase, putative 0.0468 0.0504 0.3746
Onchocerca volvulus 0.0838 0.1165 0.1429
Brugia malayi Stress-activated protein kinase jnk-1 0.196 0.3169 0.3889
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0226 0.0072 0.0529
Echinococcus multilocularis PAK box P21 Rho binding 0.0266 0.0142 0.0137
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0622 0.078 0.0775
Loa Loa (eye worm) hypothetical protein 0.0218 0.0057 0.007
Echinococcus multilocularis c src tyrosine kinase 0.0446 0.0464 0.0459
Echinococcus multilocularis dual specificity 0.0231 0.008 0.0075
Schistosoma mansoni kinase 0.0332 0.026 0.0623
Echinococcus multilocularis roundabout 2 0.0704 0.0925 0.092
Schistosoma mansoni cell adhesion molecule 0.0218 0.0057 0.0114
Schistosoma mansoni serine/threonine protein kinase 0.0423 0.0424 0.1032
Schistosoma mansoni serine/threonine protein kinase 0.1808 0.2898 0.7219
Brugia malayi Protein kinase domain containing protein 0.0382 0.035 0.0428
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.1715 0.2732 0.2727
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0786 0.1073 0.1371
Echinococcus granulosus peroxidasin 0.022 0.0061 0.0071
Brugia malayi putative serine/threonine kinase SADA gamma 0.0294 0.0193 0.0234
Loa Loa (eye worm) hypothetical protein 0.1169 0.1756 0.2155
Trichomonas vaginalis CMGC family protein kinase 0.0786 0.1073 0.7955
Schistosoma mansoni protein kinase 0.0662 0.085 0.2098
Brugia malayi Protein kinase domain containing protein 0.1293 0.1978 0.2426
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0321 0.0242 0.0305
Echinococcus multilocularis dual specificity 0.0231 0.008 0.0075
Echinococcus granulosus lachesin 0.0218 0.0057 0.0066
Echinococcus granulosus casein kinase ii subunit alpha 0.0192 0.0011 0.0007
Loa Loa (eye worm) hypothetical protein 0.0218 0.0057 0.007
Echinococcus multilocularis cyclin dependent kinase 9 0.0306 0.0215 0.0209
Schistosoma mansoni serine/threonine protein kinase 0.0227 0.0074 0.0157
Brugia malayi Immunoglobulin I-set domain containing protein 0.0297 0.0199 0.0241
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0231 0.008 0.0089
Entamoeba histolytica protein kinase domain containing protein 0.0928 0.1327 1
Plasmodium falciparum protein serine/threonine kinase-1 0.0786 0.1073 0.9195
Echinococcus granulosus MAM 0.0197 0.0019 0.0018
Entamoeba histolytica cell division protein kinase 2, putative 0.0382 0.035 0.2577
Trichomonas vaginalis AGC family protein kinase 0.052 0.0596 0.4383
Leishmania major casein kinase, putative 0.0463 0.0496 0.0626
Brugia malayi Immunoglobulin I-set domain containing protein 0.0245 0.0106 0.0128
Echinococcus granulosus ephrin type A receptor 4 A 0.0241 0.0098 0.012
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0604 0.0747 0.095
Plasmodium vivax serine/threonine kinase-1, putative 0.0786 0.1073 0.9195
Brugia malayi Immunoglobulin I-set domain containing protein 0.1206 0.1822 0.2235
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0486 0.0537 0.0679
Echinococcus granulosus tyrosine protein kinase ABL1 0.1565 0.2464 0.3173
Schistosoma mansoni serine/threonine protein kinase 0.0434 0.0443 0.108
Brugia malayi Protein kinase domain containing protein 0.0423 0.0424 0.0518
Echinococcus granulosus tyrosine protein kinase shark 0.0544 0.0639 0.0817
Schistosoma mansoni cell adhesion molecule 0.0245 0.0106 0.0237
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0248 0.0111 0.0867
Schistosoma mansoni serine/threonine-protein kinase 0.028 0.0167 0.039
Schistosoma mansoni serine/threonine protein kinase 0.1193 0.1798 0.4469
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0382 0.035 0.0438
Schistosoma mansoni serine/threonine protein kinase 0.1293 0.1978 0.4918
Schistosoma mansoni tyrosine kinase 0.0395 0.0374 0.0907
Onchocerca volvulus Serine\/threonine kinase homolog 0.0267 0.0145 0.0176
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0379 0.0346 0.0439
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0382 0.035 0.043
Brugia malayi Protein kinase domain containing protein 0.0537 0.0628 0.0769
Giardia lamblia Kinase, PLK 0.0267 0.0145 0.1002
Brugia malayi Variant SH3 domain containing protein 0.0268 0.0147 0.0178
Echinococcus granulosus serine/threonine protein kinase 0.028 0.0167 0.0209
Trypanosoma cruzi casein kinase, putative 0.0463 0.0496 0.0626
Onchocerca volvulus Serine\/threonine kinase homolog 0.0256 0.0125 0.0151
Loa Loa (eye worm) TK/FER protein kinase 0.0332 0.0261 0.032
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0838 0.1165 0.116
Schistosoma mansoni protein kinase 0.0939 0.1345 0.3336
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0294 0.0193 0.0234
Entamoeba histolytica protein kinase, putative 0.0928 0.1327 1
Loa Loa (eye worm) hypothetical protein 0.0649 0.0827 0.1016
Schistosoma mansoni hypothetical protein 0.0197 0.0019 0.002
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0418 0.0414 0.3491
Plasmodium falciparum serine/threonine protein kinase, putative 0.052 0.0596 0.5066
Echinococcus multilocularis 0.0662 0.085 0.0845
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0546 0.0643 0.0789
Loa Loa (eye worm) CMGC/DYRK/HIPK protein kinase 0.0294 0.0193 0.0237
Echinococcus granulosus casein kinase I alpha 0.0463 0.0496 0.0632
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0838 0.1165 1
Brugia malayi Protein kinase domain containing protein 0.0284 0.0175 0.0213
Brugia malayi RhoGAP domain containing protein 0.0279 0.0166 0.0202
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.0486 0.0537 0.0532
Echinococcus multilocularis casein kinase I delta 0.0463 0.0496 0.049
Loa Loa (eye worm) hypothetical protein 0.0245 0.0106 0.013
Schistosoma mansoni serine/threonine protein kinase 0.0566 0.0678 0.1668
Toxoplasma gondii aurora kinase 0.052 0.0596 0.5066
Loa Loa (eye worm) hypothetical protein 0.0532 0.0619 0.0759
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0622 0.078 0.0999
Brugia malayi Tyrosine-protein kinase abl-1 0.0917 0.1307 0.1602
Echinococcus multilocularis tyrosine kinase 0.0332 0.0261 0.0255
Trichomonas vaginalis AGC family protein kinase 0.0577 0.0699 0.5154
Brugia malayi Protein kinase domain containing protein 0.0688 0.0896 0.1098
Trichomonas vaginalis CAMK family protein kinase 0.0267 0.0145 0.1002
Schistosoma mansoni vam6/vps39 related 0.0486 0.0537 0.1315
Schistosoma mansoni serine/threonine protein kinase 0.052 0.0596 0.1462
Trypanosoma brucei protein kinase, putative 0.0208 0.0039 0.0036
Echinococcus multilocularis protein KINase family member (kin 25) 0.0559 0.0667 0.0661
Loa Loa (eye worm) TK/FAK protein kinase 0.2458 0.4058 0.4982
Schistosoma mansoni protein kinase 0.0303 0.021 0.0496
Loa Loa (eye worm) hypothetical protein 0.0189 0.0006 0.0007
Brugia malayi ephrin receptor 1 precursor 0.0207 0.0039 0.0045
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0418 0.0414 0.0509
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.1715 0.2732 0.3518
Echinococcus granulosus serine:threonine protein kinase N2 0.1193 0.1798 0.2313
Trichomonas vaginalis CAMK family protein kinase 0.0267 0.0145 0.1002
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0297 0.0199 0.0244
Loa Loa (eye worm) AGC/NDR protein kinase 0.0423 0.0424 0.0521
Entamoeba histolytica protein kinase, putative 0.052 0.0596 0.4445
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0245 0.0106 0.0101
Schistosoma mansoni serine/threonine protein kinase 0.0786 0.1073 0.2654
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0231 0.008 0.0089
Trichomonas vaginalis STE family protein kinase 0.0287 0.0181 0.127
Toxoplasma gondii AGC kinase 0.0546 0.0643 0.5472
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0382 0.035 0.0438
Echinococcus granulosus raf serine:threonine protein kinase 0.0302 0.0208 0.0261
Loa Loa (eye worm) TK/FER protein kinase 0.0332 0.0261 0.032
Echinococcus granulosus dual specificity 0.0231 0.008 0.0096
Echinococcus multilocularis dual specificity 0.0928 0.1327 0.1322
Brugia malayi Egg laying defective protein 4 0.0226 0.0072 0.0086
Echinococcus granulosus homeodomain interacting protein kinase 3 0.0294 0.0193 0.0242
Echinococcus multilocularis cyclin dependent kinase 9 0.0338 0.0271 0.0266
Echinococcus granulosus cGMP dependent protein kinase 1 0.0226 0.0072 0.0086
Plasmodium falciparum casein kinase 1 0.0463 0.0496 0.4196
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0817 0.1127 0.1381
Schistosoma mansoni atypical protein kinase C 0.0636 0.0804 0.1982
Echinococcus multilocularis lachesin 0.0218 0.0057 0.0051
Schistosoma mansoni serine/threonine protein kinase 0.0294 0.0193 0.0454
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0287 0.0181 0.0226
Echinococcus multilocularis G protein coupled receptor kinase 6 0.1041 0.1528 0.1523
Loa Loa (eye worm) hypothetical protein 0.0197 0.0019 0.0024
Echinococcus multilocularis mitogen activated protein kinase 14 0.4527 0.7754 0.7753
Echinococcus granulosus STE20 serine:threonine protein kinase 0.0583 0.0709 0.0908
Entamoeba histolytica protein kinase domain containing protein 0.0294 0.0193 0.138
Echinococcus multilocularis rac serine:threonine kinase 0.028 0.0167 0.0162
Schistosoma mansoni serine/threonine protein kinase 0.0294 0.0193 0.0453
Echinococcus multilocularis cyclin dependent kinase 19 0.1293 0.1978 0.1973
Echinococcus granulosus [G-protein-coupledreceptor] kinase 0.1041 0.1528 0.1964
Echinococcus multilocularis dual specificity 0.0231 0.008 0.0075
Brugia malayi Immunoglobulin I-set domain containing protein 0.0218 0.0057 0.0067
Echinococcus multilocularis aurora kinase A 0.052 0.0596 0.0591
Brugia malayi Immunoglobulin I-set domain containing protein 0.0218 0.0057 0.0067
Entamoeba histolytica casein kinase, putative 0.0463 0.0496 0.3683
Brugia malayi Immunoglobulin I-set domain containing protein 0.0486 0.0536 0.0655
Entamoeba histolytica protein kinase, putative 0.0419 0.0417 0.3081
Brugia malayi Fes/CIP4 homology domain containing protein 0.0544 0.064 0.0783
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0838 0.1165 0.1431
Brugia malayi Homeodomain interacting protein kinase protein 1 0.0294 0.0193 0.0234
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0268 0.0147 0.0181
Echinococcus granulosus tyrosine protein kinase Blk 0.0622 0.078 0.0999
Trichomonas vaginalis AGC family protein kinase 0.0423 0.0424 0.3094
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.0662 0.085 0.1044
Trypanosoma cruzi casein kinase, putative 0.0463 0.0496 0.0626
Leishmania major protein kinase, putative 0.0786 0.1073 0.1371
Trichomonas vaginalis AGC family protein kinase 0.052 0.0596 0.4383
Schistosoma mansoni tyrosine kinase 0.1411 0.2188 0.5444
Giardia lamblia Aurora kinase 0.052 0.0596 0.4383
Loa Loa (eye worm) TK/FER protein kinase 0.0332 0.0261 0.032
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0786 0.1073 0.1371
Loa Loa (eye worm) TK protein kinase 0.0622 0.078 0.0958
Brugia malayi p70 ribosomal S6 kinase beta 0.0546 0.0643 0.0787
Giardia lamblia Kinase, STE STE20 0.0287 0.0181 0.127
Echinococcus multilocularis fibroblast growth factor receptor 4 0.1062 0.1565 0.156
Brugia malayi EGF-like domain containing protein 0.0189 0.0006 0.0005
Toxoplasma gondii AGC kinase 0.0604 0.0747 0.6376
Echinococcus multilocularis dual specificity mitogen activated protein 0.0939 0.1345 0.134
Brugia malayi Immunoglobulin I-set domain containing protein 0.0333 0.0263 0.032
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.1808 0.2898 0.2894
Echinococcus multilocularis casein kinase I delta 0.0463 0.0496 0.049
Schistosoma mansoni nck2/grb4 0.0268 0.0147 0.034
Echinococcus granulosus maternal embryonic leucine zipper kinase 0.0207 0.0038 0.0042
Echinococcus granulosus c src tyrosine kinase 0.0446 0.0464 0.0592
Schistosoma mansoni nephrin 0.0245 0.0106 0.0237
Onchocerca volvulus Slit protein homolog 0.0189 0.0006 0.0005
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0786 0.1073 0.1371
Schistosoma mansoni serine/threonine protein kinase 0.0379 0.0346 0.0836
Entamoeba histolytica protein kinase domain containing protein 0.0231 0.008 0.0523
Brugia malayi Immunoglobulin I-set domain containing protein 0.0245 0.0106 0.0128
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0267 0.0145 0.0178
Entamoeba histolytica protein kinase, putative 0.0546 0.0643 0.4802
Echinococcus granulosus cGMP dependent protein kinase 0.0226 0.0072 0.0086
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0604 0.0747 0.095
Schistosoma mansoni tyrosine kinase 0.0446 0.0464 0.1133
Echinococcus multilocularis rho associated protein kinase 0.0703 0.0924 0.0918
Loa Loa (eye worm) hypothetical protein 0.0455 0.0481 0.0591
Schistosoma mansoni serine/threonine protein kinase 0.0294 0.0193 0.0453
Plasmodium vivax serine/threonine protein kinase 6, putative 0.052 0.0596 0.5066
Echinococcus granulosus insulin growth factor 1 receptor beta 0.108 0.1597 0.2053
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0338 0.0271 0.0336
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.4527 0.7754 1
Schistosoma mansoni serine/threonine protein kinase 0.0294 0.0193 0.0453
Trichomonas vaginalis AGC family protein kinase 0.0577 0.0699 0.5154
Trichomonas vaginalis CAMK family protein kinase 0.0294 0.0193 0.1359
Trichomonas vaginalis AGC family protein kinase 0.0455 0.0481 0.3517
Loa Loa (eye worm) AGC/PKA protein kinase 0.0604 0.0747 0.0917
Trichomonas vaginalis AGC family protein kinase 0.0228 0.0075 0.0478
Schistosoma mansoni serine/threonine kinase 0.0371 0.033 0.0798
Schistosoma mansoni serine/threonine protein kinase 0.0703 0.0924 0.2281
Echinococcus granulosus Protein kinase C brain isozyme 0.0588 0.0719 0.0921
Schistosoma mansoni serine/threonine protein kinase 0.0549 0.0649 0.1594
Echinococcus multilocularis casein kinase I alpha 0.0463 0.0496 0.049
Echinococcus multilocularis MAM 0.0197 0.0019 0.0014
Onchocerca volvulus 0.0566 0.068 0.0832
Echinococcus multilocularis cyclin dependent kinase 0.0382 0.035 0.0345
Schistosoma mansoni protein kinase 0.0463 0.0496 0.1211
Onchocerca volvulus 0.0197 0.0019 0.0021
Trichomonas vaginalis CMGC family protein kinase 0.0231 0.008 0.0516
Echinococcus multilocularis tyrosine protein kinase HCK 0.0468 0.0504 0.0499
Trichomonas vaginalis CMGC family protein kinase 0.0382 0.035 0.2541
Schistosoma mansoni kinase 0.0306 0.0215 0.0509
Plasmodium falciparum serine/threonine protein kinase KIN 0.0294 0.0193 0.1571
Loa Loa (eye worm) hypothetical protein 0.0218 0.0057 0.007
Brugia malayi Sex muscle abnormal protein 5 0.0268 0.0147 0.0178
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0371 0.0331 0.0406
Echinococcus granulosus serine:threonine protein kinase mig 15 0.1023 0.1495 0.1922
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0742 0.0994 0.127
Loa Loa (eye worm) hypothetical protein 0.0803 0.1102 0.1353
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.1715 0.2732 0.3354
Echinococcus multilocularis serine:threonine protein kinase receptor R3 0.0624 0.0782 0.0777
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0245 0.0106 0.0101
Schistosoma mansoni serine/threonine protein kinase 0.0258 0.0128 0.0293
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0287 0.0181 0.0226
Loa Loa (eye worm) TK/ABL protein kinase 0.1565 0.2464 0.3025
Brugia malayi map kinase activated protein kinase protein 2 0.0484 0.0532 0.065
Entamoeba histolytica hypothetical protein 0.0377 0.0341 0.2505
Echinococcus multilocularis N chimaerin 0.0279 0.0166 0.0161
Echinococcus granulosus aurora kinase A 0.052 0.0596 0.0762
Schistosoma mansoni roundabout 0.0218 0.0057 0.0114
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0486 0.0537 0.0679
Echinococcus granulosus activated cdc42 kinase 1 0.1169 0.1756 0.2258
Brugia malayi cyclin-dependent kinase 9 0.0306 0.0215 0.0261
Schistosoma mansoni serine/threonine protein kinase 0.196 0.3169 0.7897
Trichomonas vaginalis STE family protein kinase 0.0287 0.0181 0.127
Echinococcus granulosus calcium activated potassium channel 0.0258 0.0128 0.0158
Echinococcus granulosus titin 0.0297 0.0199 0.0249
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.1456 0.2269 0.2265
Echinococcus granulosus roundabout 2 0.0245 0.0106 0.013
Echinococcus granulosus c-Jun N-terminal kinases 0.196 0.3169 0.4083
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0187 0.0002 0.0003
Loa Loa (eye worm) thyroid receptor interactor 0.0544 0.064 0.0785
Giardia lamblia Kinase, CMGC DYRK 0.0231 0.008 0.0516
Echinococcus granulosus serine:threonine protein kinase 12 B 0.052 0.0596 0.0762
Entamoeba histolytica tyrosin kinase, putative 0.021 0.0043 0.0241
Echinococcus granulosus serine threonine protein kinase nrc 0.0248 0.0111 0.0136
Schistosoma mansoni cell adhesion molecule 0.0245 0.0106 0.0237
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0736 0.0983 0.0978
Brugia malayi Protein kinase domain containing protein 0.0332 0.0261 0.0318
Trichomonas vaginalis CAMK family protein kinase 0.0207 0.0038 0.0199
Echinococcus multilocularis serine threonine protein kinase 0.0464 0.0496 0.0491
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0786 0.1073 0.9195
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0245 0.0106 0.013
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0303 0.021 0.1717
Echinococcus granulosus protein tyrosine kinase 0.2431 0.401 0.5168
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.1009 0.147 0.1465
Trypanosoma brucei aurora B kinase 0.052 0.0596 0.0755
Echinococcus granulosus casein kinase I gamma 0.0304 0.0212 0.0266
Echinococcus granulosus serine:threonine protein kinase 0.0247 0.011 0.0135
Brugia malayi Protein kinase domain containing protein 0.0786 0.1073 0.1314
Echinococcus multilocularis calcium activated potassium channel 0.0258 0.0128 0.0123
Trypanosoma cruzi polo-like protein kinase, putative 0.0267 0.0145 0.0173
Echinococcus multilocularis calcium dependent protein kinase 0.0292 0.019 0.0184
Brugia malayi Dual specificity mitogen-activated protein kinase kinase mek-2 0.0939 0.1345 0.1649
Echinococcus granulosus tyrosine protein kinase Lyn 0.0862 0.1208 0.1552
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0279 0.0166 0.0204
Schistosoma mansoni septate junction protein 0.0218 0.0057 0.0114
Brugia malayi Variant SH3 domain containing protein 0.0268 0.0147 0.0178
Echinococcus granulosus dual specificity 0.0231 0.008 0.0096
Brugia malayi Immunoglobulin I-set domain containing protein 0.0218 0.0057 0.0067
Echinococcus multilocularis serine:threonine protein kinase N2 0.1193 0.1798 0.1794
Loa Loa (eye worm) TK/FER protein kinase 0.0332 0.0261 0.032
Trypanosoma brucei polo-like protein kinase 0.0267 0.0145 0.0173
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0604 0.0747 0.095
Trichomonas vaginalis CAMK family protein kinase 0.0339 0.0274 0.1967
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0463 0.0496 0.0609
Leishmania major protein kinase A catalytic subunit isoform 1 0.0604 0.0747 0.095
Loa Loa (eye worm) TK/EGFR protein kinase 0.0825 0.1142 0.1402
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0478 0.0523 0.0667
Schistosoma mansoni serine/threonine protein kinase 0.1551 0.2439 0.6072
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0868 0.1218 0.1213
Brugia malayi hypothetical protein 0.0486 0.0536 0.0655
Brugia malayi Protein kinase domain 0.0287 0.0181 0.0219
Echinococcus granulosus cyclin dependent kinase 7 0.0434 0.0443 0.0565
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0838 0.1165 0.1497
Echinococcus multilocularis epidermal growth factor receptor 0.0687 0.0896 0.0891
Onchocerca volvulus 0.19 0.3062 0.3758
Plasmodium falciparum calcium-dependent protein kinase 3 0.0418 0.0414 0.3491
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0604 0.0747 0.095
Trypanosoma cruzi casein kinase, putative 0.0463 0.0496 0.0626
Trichomonas vaginalis CAMK family protein kinase 0.0294 0.0193 0.1359
Schistosoma mansoni ephrin receptor 0.0241 0.0098 0.0218
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0379 0.0346 0.0439
Schistosoma mansoni rap gtpase-activating protein 0.0486 0.0537 0.1315
Echinococcus granulosus calcium dependent protein kinase 0.0292 0.019 0.0238
Loa Loa (eye worm) AGC/PKN protein kinase 0.1193 0.1798 0.2208
Schistosoma mansoni neuroglian 0.0245 0.0106 0.0237
Loa Loa (eye worm) hypothetical protein 0.0693 0.0905 0.1112
Schistosoma mansoni protein kinase 0.0287 0.0181 0.0424
Giardia lamblia Kinase, NEK 0.0228 0.0075 0.0478
Brugia malayi Protein kinase domain containing protein 0.2458 0.4058 0.498
Schistosoma mansoni serine/threonine protein kinase 0.0786 0.1073 0.2654
Onchocerca volvulus 0.0332 0.0261 0.0318
Loa Loa (eye worm) hypothetical protein 0.0486 0.0537 0.0659
Loa Loa (eye worm) CAMK/PHK protein kinase 0.0256 0.0125 0.0153
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0294 0.0193 0.0187
Echinococcus multilocularis mitogen activated protein kinase 11 0.4527 0.7754 0.7753
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.1009 0.147 0.189
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0785 0.107 0.1373
Brugia malayi hypothetical protein 0.1808 0.2898 0.3556
Brugia malayi Protein kinase domain containing protein 0.0332 0.0261 0.0318
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0676 0.0875 0.1074
Loa Loa (eye worm) G protein-coupled receptor kinase 1 0.1041 0.1528 0.1876
Echinococcus granulosus epidermal growth factor receptor 0.0825 0.1142 0.1466
Echinococcus multilocularis activin receptor type 0.2847 0.4754 0.4751
Onchocerca volvulus 0.0486 0.0537 0.0657
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0604 0.0747 0.095
Loa Loa (eye worm) hypothetical protein 0.0218 0.0057 0.007
Trichomonas vaginalis AGC family protein kinase 0.052 0.0596 0.4383
Loa Loa (eye worm) STE/STE7/MEK1 protein kinase 0.0939 0.1345 0.1652
Loa Loa (eye worm) hypothetical protein 0.0693 0.0905 0.1112
Leishmania major protein kinase A catalytic subunit 0.0604 0.0747 0.095
Plasmodium falciparum protein kinase, putative 0.0303 0.021 0.1717
Entamoeba histolytica p21-activated kinase 0.0318 0.0237 0.1714
Echinococcus multilocularis growth factor receptor bound protein 2 0.0268 0.0147 0.0142
Trypanosoma cruzi polo-like protein kinase, putative 0.0267 0.0145 0.0173
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.4527 0.7754 1
Schistosoma mansoni serine/threonine protein kinase 0.0423 0.0424 0.1032
Plasmodium vivax calcium-dependent protein kinase, putative 0.0418 0.0414 0.3491

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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