Detailed information for compound 1022973

Basic information

Technical information
  • TDR Targets ID: 1022973
  • Name: (3E,5E)-6-(1H-indol-3-yl)-5-methylhepta-3,5-d ien-2-one
  • MW: 239.312 | Formula: C16H17NO
  • H donors: 1 H acceptors: 1 LogP: 4.05 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC(=O)/C=C/C(=C(/c1c[nH]c2c1cccc2)\C)/C
  • InChi: 1S/C16H17NO/c1-11(8-9-12(2)18)13(3)15-10-17-16-7-5-4-6-14(15)16/h4-10,17H,1-3H3/b9-8+,13-11+
  • InChiKey: XYPNIPPMKPLGOZ-VKTMSVCMSA-N  


Substructure search Similarity search

Network

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Synonyms

  • (3E,5E)-6-(1H-indol-3-yl)-5-methyl-hepta-3,5-dien-2-one

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Leishmania major regulatory subunit of protein kinase a-like protein 0.0021 0.0026 0.0223
Brugia malayi ORL1-like opioid receptor 0.006 0.0218 0.0218
Onchocerca volvulus 0.0021 0.0026 0.0537
Schistosoma mansoni opsin-like receptor 0.006 0.0218 0.0392
Loa Loa (eye worm) hypothetical protein 0.025 0.1154 0.1154
Echinococcus multilocularis somatostatin receptor 0.006 0.0218 0.0392
Trypanosoma cruzi trypanothione reductase, putative 0.0019 0.0018 0.0154
Trichomonas vaginalis D-aminoacylase, putative 0.0072 0.0278 0.3896
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0125 0.054 0.094
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0154 0.0684 0.1553
Loa Loa (eye worm) hypothetical protein 0.006 0.0218 0.0218
Echinococcus granulosus neuropeptides capa receptor 0.006 0.0218 0.0392
Schistosoma mansoni biogenic amine (5HT) receptor 0.006 0.0218 0.0392
Trypanosoma brucei cyclic nucleotide-binding domain containing protein, putative 0.0021 0.0026 0.0223
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.0021
Trypanosoma brucei diacylglycerol kinase, putative 0.0045 0.0145 0.1241
Brugia malayi Melatonin receptor type 1A 0.006 0.0218 0.0218
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0029 0.0066 0.0559
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.002 0.0021 0.0038
Schistosoma mansoni biogenic amine (dopamine) receptor 0.006 0.0218 0.0392
Brugia malayi diacylglycerol kinase 0.0045 0.0145 0.0145
Brugia malayi Diacylglycerol kinase protein 2 0.0045 0.0145 0.0145
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0159 0.071 0.071
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.006 0.0218 0.0392
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0034 0.0094 0.0168
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.006 0.0218 0.0392
Echinococcus multilocularis voltage gated potassium channel 0.0049 0.0164 0.0295
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0034 0.0094 0.0168
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0021 0.0026 0.012
Brugia malayi sulfakinin receptor protein 0.006 0.0218 0.0218
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0043 0.0135 0.0243
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0142 0.0624 0.112
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0154 0.0684 0.1229
Trichomonas vaginalis diacylglycerol kinase, putative 0.0045 0.0145 0.1897
Loa Loa (eye worm) hypothetical protein 0.006 0.0218 0.0218
Plasmodium falciparum transporter, putative 0.002 0.0021 0.031
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0154 0.0684 0.1553
Leishmania major hypothetical protein, unknown function 0.0021 0.0026 0.0223
Mycobacterium ulcerans hypothetical protein 0.0132 0.0577 0.1006
Brugia malayi hypothetical protein 0.0183 0.0825 0.0825
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0154 0.0684 1
Entamoeba histolytica diacylglycerol kinase, putative 0.0045 0.0145 0.0151
Mycobacterium ulcerans transcriptional regulatory protein 0.0021 0.0026 0.0014
Loa Loa (eye worm) hypothetical protein 0.0072 0.0278 0.0278
Echinococcus granulosus cAMP dependent protein kinase type I beta 0.0021 0.0026 0.0047
Schistosoma mansoni survival motor neuron protein 0.0037 0.0109 0.0195
Schistosoma mansoni hypothetical protein 0.006 0.0218 0.0392
Trypanosoma brucei cyclic nucleotide-binding domain containing protein, putative 0.0021 0.0026 0.0223
Echinococcus granulosus ubiquitin specific protease 41 0.0033 0.0088 0.0158
Mycobacterium tuberculosis Probable lipase LipE 0.0072 0.0278 0.0468
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0016 0.0004 0.0006
Brugia malayi Cyclic-nucleotide gated cation channel, C. elegans tax-4 ortholog 0.0021 0.0026 0.0026
Trypanosoma cruzi hypothetical protein, conserved 0.0154 0.0684 0.5884
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.008 0.0318 0.057
Toxoplasma gondii hypoxia- inducible factor prolyl hydroxylase (phd2), putative 0.0041 0.0125 0.0282
Trichomonas vaginalis diacylglycerol kinase, putative 0.0045 0.0145 0.1897
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0019 0.0018 0.0041
Schistosoma mansoni hypothetical protein 0.0045 0.0145 0.026
Schistosoma mansoni voltage-gated potassium channel 0.0016 0.0003 0.0005
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0033 0.0088 0.1047
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0115 0.0492 0.0883
Loa Loa (eye worm) AGC/PKG protein kinase 0.0021 0.0026 0.0026
Loa Loa (eye worm) hypothetical protein 0.006 0.0218 0.0218
Schistosoma mansoni neuropeptide receptor 0.006 0.0218 0.0392
Echinococcus multilocularis inositol monophosphatase 1 0.0029 0.0066 0.0118
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0154 0.0684 0.1553
Mycobacterium ulcerans diacylglycerol kinase 0.0045 0.0145 0.0228
Loa Loa (eye worm) hypothetical protein 0.006 0.0218 0.0218
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0016 0.0003 0.0005
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0154 0.0684 1
Plasmodium falciparum amino acid transporter, putative 0.002 0.0021 0.031
Onchocerca volvulus 0.0072 0.0278 0.5651
Loa Loa (eye worm) hypothetical protein 0.006 0.0218 0.0218
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0896 0.4338 0.779
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0154 0.0684 1
Onchocerca volvulus 0.0072 0.0278 0.5651
Toxoplasma gondii aldehyde dehydrogenase 0.0037 0.0106 0.024
Loa Loa (eye worm) ceramide kinase 0.0045 0.0145 0.0145
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0019 0.0018 0.0033
Echinococcus granulosus g protein coupled receptor 0.006 0.0218 0.0392
Trichomonas vaginalis cAMP-dependent protein kinase regulatory subunit, putative 0.0021 0.0026 0.012
Brugia malayi Tachykinin-like peptides receptor 99D 0.006 0.0218 0.0218
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.006 0.0218 0.0218
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0154 0.0684 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0019 0.0018 0.0154
Mycobacterium tuberculosis Probable glutamine-transport ATP-binding protein ABC transporter GlnQ 0.0021 0.0026 0.0014
Toxoplasma gondii histone lysine methyltransferase SET1 0.0061 0.0225 0.0511
Mycobacterium ulcerans hypothetical protein 0.1146 0.5568 1
Echinococcus granulosus beta LACTamase domain containing family member 0.0072 0.0278 0.0499
Brugia malayi hypothetical protein 0.006 0.0218 0.0218
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.0154 0.0684 0.1229
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0154 0.0684 1
Trypanosoma cruzi Flagellar Member 6 0.0021 0.0026 0.0223
Brugia malayi Dopamine receptor protein 1 0.006 0.0218 0.0218
Schistosoma mansoni amine GPCR 0.006 0.0218 0.0392
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.006 0.0218 0.0392
Onchocerca volvulus 0.006 0.0218 0.4437
Toxoplasma gondii PHD-finger domain-containing protein 0.0024 0.0045 0.0101
Brugia malayi Ceramide kinase 0.0045 0.0145 0.0145
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0896 0.4338 0.779
Loa Loa (eye worm) hypothetical protein 0.006 0.0218 0.0218
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0154 0.0684 0.1553
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0125 0.054 0.094
Echinococcus granulosus neuropeptide receptor 0.006 0.0218 0.0392
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0019 0.0018 0.0154
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0019 0.0018 0.0154
Schistosoma mansoni jumonji/arid domain-containing protein 0.0031 0.0079 0.0142
Loa Loa (eye worm) inositol-1 0.0029 0.0066 0.0066
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.006 0.0218 0.0392
Echinococcus multilocularis G-protein coupled receptor, putative 0.006 0.0218 0.0392
Plasmodium falciparum cGMP-dependent protein kinase 0.0021 0.0026 0.0386
Loa Loa (eye worm) thioredoxin reductase 0.0055 0.0195 0.0195
Mycobacterium leprae conserved hypothetical protein 0.0072 0.0278 0.4318
Treponema pallidum cyclic nucleotide binding protein 0.0021 0.0026 0.0169
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0037 0.0106 0.0191
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0154 0.0684 0.5884
Echinococcus granulosus biogenic amine 5HT receptor 0.006 0.0218 0.0392
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0154 0.0684 0.5884
Schistosoma mansoni voltage-gated potassium channel 0.0016 0.0003 0.0005
Brugia malayi Egg laying defective protein 4 0.0021 0.0026 0.0026
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0072 0.0278 0.0278
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0154 0.0684 0.1553
Trypanosoma cruzi cAMP binding protein, putative 0.0021 0.0026 0.0223
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0029 0.0066 0.0007
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0154 0.0684 1
Schistosoma mansoni voltage-gated potassium channel 0.0016 0.0003 0.0005
Leishmania major hypothetical protein, conserved 0.0045 0.0145 0.1241
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0072 0.0278 0.0468
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0154 0.0684 1
Mycobacterium leprae Probable lipase LipE 0.0072 0.0278 0.4318
Schistosoma mansoni biogenic amine receptor 0.006 0.0218 0.0392
Trypanosoma cruzi 2OG-Fe(II) oxygenase superfamily, putative 0.0041 0.0125 0.1068
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.006 0.0218 0.0218
Schistosoma mansoni amine GPCR 0.006 0.0218 0.0392
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0154 0.0684 1
Loa Loa (eye worm) hypothetical protein 0.0061 0.0226 0.0226
Loa Loa (eye worm) hypothetical protein 0.006 0.0218 0.0218
Loa Loa (eye worm) hypothetical protein 0.006 0.0218 0.0218
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0251 0.1163 1
Mycobacterium ulcerans hypothetical protein 0.0021 0.0026 0.0014
Schistosoma mansoni hypothetical protein 0.0097 0.0402 0.0722
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0159 0.071 0.1275
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.006 0.0218 0.0392
Schistosoma mansoni camp-dependent protein kinase regulatory chain 0.0021 0.0026 0.0047
Trypanosoma cruzi trypanothione reductase, putative 0.0055 0.0195 0.167
Brugia malayi hypothetical protein 0.006 0.0218 0.0218
Mycobacterium tuberculosis Conserved protein 0.1146 0.5568 1
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0028 0.0062 0.0111
Echinococcus granulosus tachykinin peptides receptor 99D 0.006 0.0218 0.0392
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0016 0.0003 0.0005
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit. C. elegans exp-2 ortholog 0.0016 0.0003 0.0003
Schistosoma mansoni hypothetical protein 0.0097 0.0402 0.0722
Echinococcus multilocularis survival motor neuron protein 1 0.0183 0.0825 0.1482
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0029 0.0066 0.0148
Trichomonas vaginalis conserved hypothetical protein 0.0154 0.0684 1
Schistosoma mansoni camp-dependent protein kinase type I-beta regulatory subunit 0.0021 0.0026 0.0047
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0154 0.0684 1
Echinococcus multilocularis g-protein coupled receptor 0.006 0.0218 0.0392
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0033 0.0088 0.0754
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0142 0.0624 0.0624
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0034 0.0094 0.0168
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0154 0.0684 0.5884
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0154 0.0684 0.5884
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0044 0.0143 0.0257
Schistosoma mansoni tar DNA-binding protein 0.0117 0.0499 0.0897
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0154 0.0684 1
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0142 0.0624 0.112
Echinococcus multilocularis neuropeptides capa receptor 0.006 0.0218 0.0392
Mycobacterium ulcerans hypothetical protein 0.0021 0.0026 0.0014
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0146 0.0643 0.9375
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.006 0.0218 0.0392
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0742 0.3578 0.6426
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0019 0.0018 0.0154
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0154 0.0684 1
Brugia malayi prolyl 4-hydroxylase 0.0041 0.0125 0.0125
Onchocerca volvulus 0.0037 0.0109 0.2207
Giardia lamblia hypothetical protein 0.0154 0.0684 0.1542
Leishmania major hypothetical protein, conserved 0.0045 0.0145 0.1241
Echinococcus granulosus tm gpcr rhodopsin 0.006 0.0218 0.0392
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0055 0.0195 0.0318
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0159 0.071 0.071
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0125 0.054 0.094
Toxoplasma gondii diacylglycerol kinase, putative 0.0045 0.0145 0.0327
Echinococcus multilocularis dnaJ subfamily B 0.0459 0.2183 0.3921
Loa Loa (eye worm) hypothetical protein 0.006 0.0218 0.0218
Schistosoma mansoni hypothetical protein 0.0171 0.0765 0.1374
Trichomonas vaginalis conserved hypothetical protein 0.0154 0.0684 1
Onchocerca volvulus 0.002 0.0021 0.0431
Echinococcus multilocularis biogenic amine (5HT) receptor 0.006 0.0218 0.0392
Schistosoma mansoni neuropathy target esterase/swiss cheese-related protein 0.0021 0.0026 0.0047
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0142 0.0624 0.112
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0079 0.0314 0.0564
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0251 0.1163 1
Schistosoma mansoni cpg binding protein 0.0034 0.0093 0.0166
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0154 0.0684 1
Echinococcus granulosus rhodopsin orphan GPCR 0.006 0.0218 0.0392
Loa Loa (eye worm) glutathione reductase 0.0055 0.0195 0.0195
Schistosoma mansoni neuropeptide f receptor 76f 0.006 0.0218 0.0392
Loa Loa (eye worm) melatonin receptor type 1A 0.006 0.0218 0.0218
Loa Loa (eye worm) neuropeptide F receptor 0.006 0.0218 0.0218
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0154 0.0684 1
Brugia malayi hypothetical protein 0.0015 0.0001 0.0001
Mycobacterium tuberculosis Conserved hypothetical protein 0.0132 0.0577 0.1006
Brugia malayi Latrophilin receptor protein 2 0.0079 0.0314 0.0314
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0142 0.0624 0.112
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0079 0.0314 0.0564
Echinococcus multilocularis tar DNA binding protein 0.0117 0.0499 0.0897
Brugia malayi hypothetical protein 0.0028 0.0062 0.0062
Schistosoma mansoni hypothetical protein 0.006 0.0218 0.0392
Schistosoma mansoni peptide (allatostatin)-like receptor 0.006 0.0218 0.0392
Toxoplasma gondii hypothetical protein 0.0041 0.0125 0.0282
Leishmania major hypothetical protein, conserved 0.0041 0.0125 0.1068
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.002 0.0021 0.0021
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.0154 0.0684 0.0684
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.006 0.0218 0.0392
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.006 0.0218 0.0392
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0033 0.0088 0.0158
Brugia malayi beta-lactamase family protein 0.0072 0.0278 0.0278
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.002 0.0021 0.0038
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0019 0.0018 0.0269
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0019 0.0018 0.0154
Brugia malayi hypothetical protein 0.0045 0.0145 0.0145
Echinococcus granulosus neuropeptide FF receptor 2 0.006 0.0218 0.0392
Onchocerca volvulus 0.006 0.0218 0.4437
Leishmania major hypothetical protein, conserved 0.0021 0.0026 0.0223
Mycobacterium tuberculosis Probable dehydrogenase 0.0125 0.054 0.094
Brugia malayi F/Y-rich N-terminus family protein 0.0018 0.0013 0.0013
Leishmania major mitochondrial DNA polymerase beta 0.0251 0.1163 1
Brugia malayi RNA binding protein 0.0117 0.0499 0.0499
Schistosoma mansoni voltage-gated potassium channel 0.0016 0.0003 0.0005
Trypanosoma cruzi hypothetical protein, conserved 0.0154 0.0684 0.5884
Mycobacterium ulcerans aldehyde dehydrogenase 0.0037 0.0106 0.0158
Brugia malayi hypothetical protein 0.006 0.0218 0.0218
Echinococcus granulosus dnaJ subfamily B 0.0459 0.2183 0.3921
Echinococcus multilocularis ceramide kinase 0.0045 0.0145 0.026
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0035 0.0099 0.0847
Echinococcus granulosus tm gpcr rhodopsin 0.006 0.0218 0.0392
Onchocerca volvulus Neuropeptide F receptor homolog 0.006 0.0218 0.4437
Echinococcus granulosus thioredoxin glutathione reductase 0.0055 0.0195 0.035
Brugia malayi hypothetical protein 0.006 0.0218 0.0218
Trypanosoma cruzi regulatory subunit of protein kinase a-like protein, putative 0.0021 0.0026 0.0223
Brugia malayi PHD-finger family protein 0.0024 0.0045 0.0045
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0154 0.0684 0.1229
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0019 0.0018 0.0154
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.006 0.0218 0.0392
Brugia malayi hypothetical protein 0.002 0.0021 0.0021
Plasmodium falciparum ataxin-2 like protein, putative 0.0015 0.0001 0.0008
Echinococcus multilocularis g protein coupled receptor 0.006 0.0218 0.0392
Echinococcus granulosus tm gpcr rhodopsin 0.006 0.0218 0.0392
Echinococcus multilocularis sex peptide receptor 0.006 0.0218 0.0392
Brugia malayi TAR-binding protein 0.0117 0.0499 0.0499
Brugia malayi jmjC domain containing protein 0.008 0.0318 0.0318
Schistosoma mansoni aldehyde dehydrogenase 0.0037 0.0106 0.0191
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0154 0.0684 0.5884
Mycobacterium tuberculosis Conserved hypothetical protein 0.0021 0.0026 0.0014
Schistosoma mansoni neuropeptide F-like receptor 0.006 0.0218 0.0392
Loa Loa (eye worm) hypothetical protein 0.0045 0.0145 0.0145
Brugia malayi hypothetical protein 0.006 0.0218 0.0218
Loa Loa (eye worm) hypothetical protein 0.0072 0.0278 0.0278
Schistosoma mansoni neuropeptide F-like receptor 0.006 0.0218 0.0392
Trypanosoma brucei Sphingosine kinase 0.0045 0.0145 0.1241
Echinococcus granulosus tar DNA binding protein 0.0117 0.0499 0.0897
Brugia malayi hypothetical protein 0.006 0.0218 0.0218
Loa Loa (eye worm) hypothetical protein 0.0041 0.0125 0.0125
Loa Loa (eye worm) hypothetical protein 0.006 0.0218 0.0218
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.006 0.0218 0.0392
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0154 0.0684 1
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0037 0.0106 0.091
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0019 0.0018 0.0033
Mycobacterium tuberculosis Probable transcriptional regulatory protein Cmr 0.0021 0.0026 0.0014
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0154 0.0684 1
Onchocerca volvulus 0.0021 0.0026 0.0537
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.002 0.0021 0.0038
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0154 0.0684 0.1553
Toxoplasma gondii oxidoreductase, 2OG-Fe(II) oxygenase family protein 0.0434 0.2061 0.4678
Schistosoma mansoni hypothetical protein 0.0037 0.0109 0.0195
Loa Loa (eye worm) hypothetical protein 0.0045 0.0145 0.0145
Schistosoma mansoni serine/threonine protein kinase 0.0021 0.0026 0.0047
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0154 0.0684 1
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.006 0.0218 0.0392
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.002 0.0021 0.0047
Echinococcus granulosus cGMP dependent protein kinase 1 0.0021 0.0026 0.0047
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0033 0.0088 0.0158
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.008 0.0318 0.057
Trypanosoma cruzi 2OG-Fe(II) oxygenase superfamily, putative 0.0041 0.0125 0.1068
Echinococcus granulosus 7TM GPCR rhodopsin 0.006 0.0218 0.0392
Mycobacterium ulcerans hypothetical protein 0.0072 0.0278 0.0468
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0139 0.0609 0.1064
Brugia malayi putative neuropeptide receptor 0.006 0.0218 0.0218
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0029 0.0066 0.0707
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.002 0.0021 0.0047
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0154 0.0684 0.1553
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0154 0.0684 0.5884
Plasmodium falciparum glutathione reductase 0.0019 0.0018 0.0269
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0154 0.0684 0.1229
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0154 0.0684 1
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0239 0.1101 0.1101
Echinococcus multilocularis rhodopsin orphan GPCR 0.006 0.0218 0.0392
Mycobacterium tuberculosis Conserved hypothetical protein 0.0021 0.0026 0.0014
Loa Loa (eye worm) neuropeptide F receptor 0.006 0.0218 0.0218
Schistosoma mansoni cpg binding protein 0.0034 0.0093 0.0166
Schistosoma mansoni rhodopsin-like orphan GPCR 0.006 0.0218 0.0392
Brugia malayi G protein-coupled receptor F59B2.13 0.006 0.0218 0.0218
Schistosoma mansoni jumonji/arid domain-containing protein 0.0031 0.0079 0.0142
Echinococcus granulosus potassium voltage gated channel protein 0.0016 0.0003 0.0005
Brugia malayi Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit 0.0061 0.0226 0.0226
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.006 0.0218 0.0392
Echinococcus multilocularis rhodopsin orphan GPCR 0.006 0.0218 0.0392
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0044 0.0143 0.0225
Mycobacterium tuberculosis Probable reductase 0.0125 0.054 0.094
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.0154 0.0684 0.1229
Mycobacterium tuberculosis Conserved protein 0.0072 0.0278 0.0468
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0044 0.0143 0.0143
Loa Loa (eye worm) hypothetical protein 0.0115 0.0492 0.0492
Plasmodium falciparum phosphodiesterase delta, putative 0.0154 0.0684 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.006 0.0218 0.0392
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.006 0.0218 0.0392
Trypanosoma cruzi hypothetical protein, conserved 0.0154 0.0684 0.5884
Schistosoma mansoni voltage-gated potassium channel 0.0028 0.0063 0.0113
Schistosoma mansoni 60S ribosomal protein L21 0.0028 0.0063 0.0113
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0168 0.0752 0.1705
Trypanosoma cruzi cAMP-specific phosphodiesterase, putative 0.0154 0.0684 0.5884
Onchocerca volvulus 0.006 0.0218 0.4437
Toxoplasma gondii hypothetical protein 0.002 0.0021 0.0047
Schistosoma mansoni rhodopsin-like orphan GPCR 0.006 0.0218 0.0392
Schistosoma mansoni sphingoid long chain base kinase 0.1146 0.5568 1
Onchocerca volvulus 0.006 0.0218 0.4437
Loa Loa (eye worm) hypothetical protein 0.0072 0.0278 0.0278
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.0154 0.0684 1
Echinococcus multilocularis cAMP dependent protein kinase regulatory 0.0021 0.0026 0.0047
Echinococcus multilocularis G protein coupled receptor 139 0.006 0.0218 0.0392
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.025 0.1154 0.1154
Echinococcus multilocularis acylglycerol kinase, mitochondrial 0.0045 0.0145 0.026
Loa Loa (eye worm) hypothetical protein 0.006 0.0218 0.0218
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0033 0.0088 0.1047
Loa Loa (eye worm) hypothetical protein 0.0042 0.013 0.013
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0033 0.0088 0.0088
Brugia malayi N-terminal motif family protein 0.0021 0.0026 0.0026
Echinococcus multilocularis ubiquitin specific protease 41 0.0033 0.0088 0.0158
Trypanosoma cruzi hypothetical protein, conserved 0.0154 0.0684 0.5884
Echinococcus multilocularis serotonin transporter 0.0115 0.0492 0.0883
Toxoplasma gondii hypothetical protein 0.002 0.0021 0.0047
Schistosoma mansoni serine/threonine protein kinase 0.0021 0.0026 0.0047
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.006 0.0218 0.0392
Echinococcus multilocularis hyperpolarization activated cyclic 0.0034 0.0094 0.0168
Echinococcus granulosus G protein coupled receptor 139 0.006 0.0218 0.0392
Echinococcus granulosus g protein coupled receptor 0.006 0.0218 0.0392
Trypanosoma cruzi regulatory subunit of protein kinase a-like protein, putative 0.0021 0.0026 0.0223
Echinococcus granulosus 7tm_1 domain containing protein 0.006 0.0218 0.0392
Schistosoma mansoni microtubule-associated protein tau 0.0419 0.1986 0.3566
Echinococcus granulosus Diacylglycerol kinase zeta 0.0045 0.0145 0.026
Loa Loa (eye worm) follicle stimulating hormone receptor 0.006 0.0218 0.0218
Echinococcus granulosus GPCR family 2 0.0079 0.0314 0.0564
Loa Loa (eye worm) hypothetical protein 0.0079 0.0314 0.0314
Trypanosoma cruzi hypothetical protein, conserved 0.0021 0.0026 0.0223
Brugia malayi MH2 domain containing protein 0.0148 0.0655 0.0655
Schistosoma mansoni voltage-gated potassium channel 0.0016 0.0003 0.0005
Brugia malayi GnHR receptor homolog 0.006 0.0218 0.0218
Trypanosoma cruzi Sphingosine kinase 0.0045 0.0145 0.1241
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0142 0.0624 0.112
Leishmania major diacylglycerol kinase, putative 0.0045 0.0145 0.1241
Mycobacterium ulcerans regulatory protein 0.0021 0.0026 0.0014
Echinococcus multilocularis rhodopsin orphan GPCR 0.006 0.0218 0.0392
Echinococcus granulosus sodium channel protein 0.0036 0.0101 0.0181
Loa Loa (eye worm) hypothetical protein 0.006 0.0218 0.0218
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0036 0.0101 0.0862
Entamoeba histolytica diacylglycerol kinase, putative 0.0045 0.0145 0.0151
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0034 0.0094 0.0168
Brugia malayi Serotonin receptor 0.006 0.0218 0.0218
Brugia malayi neuropeptide F receptor 0.006 0.0218 0.0218
Schistosoma mansoni opsin-like receptor 0.006 0.0218 0.0392
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0072 0.0278 0.0499
Echinococcus granulosus lysine specific demethylase 5A 0.0031 0.0079 0.0142
Loa Loa (eye worm) hypothetical protein 0.1146 0.5568 0.5568
Brugia malayi CXXC zinc finger family protein 0.0032 0.0084 0.0084
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.0021
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0033 0.0088 0.0754
Loa Loa (eye worm) hypothetical protein 0.006 0.0218 0.0218
Echinococcus granulosus orexin receptor type 2 0.006 0.0218 0.0392
Toxoplasma gondii oxidoreductase, 2OG-Fe(II) oxygenase family protein 0.0041 0.0125 0.0282
Brugia malayi Hypothetical UPF0028 protein ZK370.4 in chromosome III, putative 0.0021 0.0026 0.0026
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0154 0.0684 1
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0154 0.0684 1
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0021 0.0026 0.0047
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0896 0.4338 0.779
Trypanosoma brucei trypanothione reductase 0.0055 0.0195 0.167
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0154 0.0684 0.1553
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0049 0.0164 0.0164
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.002 0.0021 0.0038
Schistosoma mansoni amine GPCR 0.006 0.0218 0.0392
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0142 0.0624 0.0624
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0154 0.0684 1
Schistosoma mansoni neuropeptide receptor 0.006 0.0218 0.0392
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0019 0.0018 0.0018
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0154 0.0684 1
Loa Loa (eye worm) serotonin transporter b 0.0115 0.0492 0.0492
Trypanosoma cruzi cyclic nucleotide-binding domain containing protein, putative 0.0021 0.0026 0.0223
Loa Loa (eye worm) hypothetical protein 0.006 0.0218 0.0218
Schistosoma mansoni hypothetical protein 0.0079 0.0314 0.0564
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.0021 0.0026 0.0059
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.0021 0.0026 0.0059
Echinococcus granulosus alpha 1A adrenergic receptor 0.006 0.0218 0.0392
Loa Loa (eye worm) hypothetical protein 0.006 0.0218 0.0218
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.0154 0.0684 0.1229
Schistosoma mansoni rhodopsin-like orphan GPCR 0.006 0.0218 0.0392
Schistosoma mansoni hypothetical protein 0.0459 0.2183 0.3921
Schistosoma mansoni sphingosine kinase A B 0.1146 0.5568 1
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0021 0.0026 0.0047
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.002 0.0021 0.0038
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0019 0.0018 0.0269
Echinococcus multilocularis g protein coupled receptor 0.006 0.0218 0.0392
Giardia lamblia Hypothetical protein 0.0154 0.0684 0.1542
Plasmodium vivax hypothetical protein, conserved 0.002 0.0021 0.031
Trichomonas vaginalis inositol monophosphatase, putative 0.0029 0.0066 0.0707
Plasmodium vivax hypothetical protein, conserved 0.0072 0.0278 0.4061
Treponema pallidum cyclic nucleotide binding protein 0.0021 0.0026 0.0169
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0154 0.0684 1
Loa Loa (eye worm) PDE1B protein 0.0154 0.0684 0.0684
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0742 0.3578 0.6426
Giardia lamblia PHD finger protein 15 0.0024 0.0045 0.0061
Echinococcus multilocularis expressed conserved protein 0.0021 0.0026 0.0047
Schistosoma mansoni calcium/calmodulin-dependent 35-cyclic nucleotide phosphodiesterase 0.0154 0.0684 0.1229
Onchocerca volvulus 0.006 0.0218 0.4437
Echinococcus multilocularis neuropeptide receptor A26 0.006 0.0218 0.0392
Mycobacterium ulcerans lipase LipD 0.0072 0.0278 0.0468
Mycobacterium tuberculosis Probable conserved transmembrane protein 0.0021 0.0026 0.0014
Echinococcus granulosus rhodopsin orphan GPCR 0.006 0.0218 0.0392
Loa Loa (eye worm) hypothetical protein 0.006 0.0218 0.0218
Echinococcus granulosus PHD finger protein rhinoceros 0.0024 0.0045 0.008
Loa Loa (eye worm) latrophilin receptor protein 2 0.0079 0.0314 0.0314
Toxoplasma gondii cAMP-dependent protein kinase regulatory subunit 0.0021 0.0026 0.0059
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0072 0.0278 0.0278
Loa Loa (eye worm) hypothetical protein 0.2047 1 1
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0139 0.0609 0.1064
Echinococcus multilocularis Diacylglycerol kinase theta 0.0045 0.0145 0.026
Echinococcus multilocularis fmrfamide receptor 0.006 0.0218 0.0392
Echinococcus granulosus serotonin receptor 0.006 0.0218 0.0392
Mycobacterium ulcerans hypothetical protein 0.0021 0.0026 0.0014
Loa Loa (eye worm) hypothetical protein 0.0072 0.0278 0.0278
Echinococcus granulosus hyperpolarization activated cyclic 0.0034 0.0094 0.0168
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0896 0.4338 0.4338
Loa Loa (eye worm) hypothetical protein 0.006 0.0218 0.0218
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0021 0.0026 0.0537
Trichomonas vaginalis bmru protein, putative 0.0045 0.0145 0.1897
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0034 0.0094 0.0168
Entamoeba histolytica diacylglycerol kinase, putative 0.0045 0.0145 0.0151
Trypanosoma cruzi hypothetical protein, conserved 0.0072 0.0278 0.2386
Schistosoma mansoni adenoreceptor 0.006 0.0218 0.0392
Loa Loa (eye worm) hypothetical protein 0.0115 0.0492 0.0492
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.002 0.0021 0.0021
Echinococcus multilocularis cpg binding protein 0.0034 0.0093 0.0166
Echinococcus granulosus potassium voltage gated channel subfamily C 0.0016 0.0003 0.0005
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.006 0.0218 0.0392
Onchocerca volvulus 0.002 0.0021 0.0431
Loa Loa (eye worm) hypothetical protein 0.006 0.0218 0.0218
Trichomonas vaginalis esterase, putative 0.0072 0.0278 0.3896
Loa Loa (eye worm) MH2 domain-containing protein 0.0148 0.0655 0.0655
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0029 0.0066 0.0559
Schistosoma mansoni prolyl 4-hydroxylase alpha subunit 1 0.0041 0.0125 0.0224
Plasmodium vivax ataxin-2 like protein, putative 0.0015 0.0001 0.0008
Echinococcus granulosus uncharacterized sodium dependent transporter 0.002 0.0021 0.0038
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0021 0.0026 0.0047
Loa Loa (eye worm) prolyl 4-hydroxylase 2 0.0041 0.0125 0.0125
Onchocerca volvulus 0.0045 0.0145 0.2944
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0154 0.0684 1
Loa Loa (eye worm) transcription factor SMAD2 0.0148 0.0655 0.0655
Echinococcus granulosus thyrotropin releasing hormone receptor 0.006 0.0218 0.0392
Schistosoma mansoni rhodopsin-like orphan GPCR 0.006 0.0218 0.0392
Brugia malayi AKH receptor 0.006 0.0218 0.0218
Echinococcus multilocularis tachykinin peptides receptor 99D 0.006 0.0218 0.0392
Echinococcus multilocularis alpha 1A adrenergic receptor 0.006 0.0218 0.0392
Loa Loa (eye worm) hypothetical protein 0.006 0.0218 0.0218
Plasmodium vivax rap guanine nucleotide exchange factor, putative 0.0021 0.0026 0.0386
Echinococcus multilocularis g protein coupled receptor 0.006 0.0218 0.0392
Schistosoma mansoni alpha-1 adrenergic receptor 0.006 0.0218 0.0392
Trypanosoma brucei protein kinase A regulatory subunit 0.0021 0.0026 0.0223
Brugia malayi G protein-coupled receptor 0.006 0.0218 0.0218
Trypanosoma brucei hypothetical protein, conserved 0.0045 0.0145 0.1241
Loa Loa (eye worm) hypothetical protein 0.0016 0.0003 0.0003
Trypanosoma brucei cAMP response protein 1, putative 0.0021 0.0026 0.0223
Echinococcus multilocularis potassium voltage gated channel subfamily A 0.0059 0.0215 0.0386
Echinococcus granulosus cpg binding protein 0.0034 0.0093 0.0166
Schistosoma mansoni voltage-gated potassium channel 0.0061 0.0226 0.0405
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.0154 0.0684 0.1229
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.0021
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0119 0.0511 0.439
Schistosoma mansoni histamine h1 receptor 0.006 0.0218 0.0392
Leishmania major hypothetical protein, conserved 0.0154 0.0684 0.5884
Brugia malayi Bromodomain containing protein 0.0024 0.0045 0.0045
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0117 0.0499 0.0499
Echinococcus granulosus cGMP dependent protein kinase 1 0.0021 0.0026 0.0047
Schistosoma mansoni rhodopsin-like orphan GPCR 0.006 0.0218 0.0392
Schistosoma mansoni aldehyde dehydrogenase 0.0037 0.0106 0.0191
Trichomonas vaginalis cAMP-dependent protein kinase type I-beta regulatory subunit, putative 0.0021 0.0026 0.012
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0036 0.0101 0.0181
Echinococcus granulosus geminin 0.0097 0.0402 0.0722
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.002 0.0021 0.0038
Echinococcus granulosus hypothetical protein 0.006 0.0218 0.0392
Trypanosoma brucei Diacylglycerol kinase catalytic domain containing protein, putative 0.0045 0.0145 0.1241
Brugia malayi hypothetical protein 0.006 0.0218 0.0218
Loa Loa (eye worm) TAR-binding protein 0.0117 0.0499 0.0499
Trichomonas vaginalis D-aminoacylase, putative 0.0072 0.0278 0.3896
Brugia malayi beta-lactamase 0.0072 0.0278 0.0278
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0029 0.0066 0.0559
Plasmodium falciparum phd finger protein, putative 0.0024 0.0045 0.0655
Loa Loa (eye worm) hypothetical protein 0.0045 0.0145 0.0145
Onchocerca volvulus 0.006 0.0218 0.4437
Trypanosoma brucei cAMP-specific phosphodiesterase, putative 0.0154 0.0684 0.5884
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.006 0.0218 0.0392
Trichomonas vaginalis penicillin-binding protein, putative 0.0072 0.0278 0.3896
Leishmania major diacylglycerol kinase-like protein 0.0045 0.0145 0.1241
Toxoplasma gondii PHD-finger domain-containing protein 0.0024 0.0045 0.0101
Echinococcus granulosus g protein coupled receptor 0.006 0.0218 0.0392
Schistosoma mansoni proteasome subunit alpha 6 (T01 family) 0.0045 0.0145 0.026
Echinococcus granulosus Potassium voltage gated channel protein Shaw 0.0016 0.0003 0.0005
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0154 0.0684 1
Echinococcus granulosus neuropeptide s receptor 0.006 0.0218 0.0392
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0035 0.0099 0.0847
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0154 0.0684 1
Echinococcus multilocularis potassium voltage gated channel protein 0.0016 0.0003 0.0005
Toxoplasma gondii NADPH-glutathione reductase 0.0019 0.0018 0.0041
Echinococcus multilocularis high affinity cAMP specific 3',5' cyclic 0.0154 0.0684 0.1229
Echinococcus multilocularis sodium channel protein 0.0036 0.0101 0.0181
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0154 0.0684 1
Echinococcus granulosus sphingosine kinase 1 0.1146 0.5568 1
Echinococcus granulosus ceramide kinase 0.0045 0.0145 0.026
Leishmania major hypothetical protein, unknown function 0.0041 0.0125 0.1068
Echinococcus granulosus g-protein coupled receptor 0.006 0.0218 0.0392
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0019 0.0018 0.0154
Trichomonas vaginalis diacylglycerol kinase, epsilon, putative 0.0045 0.0145 0.1897
Echinococcus granulosus peptide allatostatin:somatostatin 0.006 0.0218 0.0392
Schistosoma mansoni voltage-gated potassium channel 0.0049 0.0164 0.0295
Trypanosoma brucei Flagellar Member 6 0.0021 0.0026 0.0223
Mycobacterium tuberculosis Probable lipase LipD 0.0072 0.0278 0.0468
Trypanosoma cruzi cAMP response protein 1 0.0021 0.0026 0.0223
Schistosoma mansoni transcription factor LCR-F1 0.0028 0.0062 0.0111
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0019 0.0018 0.0154
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0154 0.0684 0.0684
Brugia malayi neuropeptide F receptor 0.006 0.0218 0.0218
Echinococcus multilocularis dro:myosuppressin receptor 0.006 0.0218 0.0392
Schistosoma mansoni diacylglycerol kinase theta 0.0045 0.0145 0.026
Echinococcus granulosus serotonin transporter 0.0115 0.0492 0.0883
Schistosoma mansoni sodium-dependent amino acid transporter 0.002 0.0021 0.0038
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.006 0.0218 0.0392
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0079 0.0314 0.0564
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0154 0.0684 0.1553
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.002 0.0021 0.0038
Echinococcus granulosus microtubule associated protein 2 0.0419 0.1986 0.3566
Echinococcus granulosus prolyl 4 hydroxylase subunit alpha 1 0.0041 0.0125 0.0224
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0239 0.1101 0.1977
Brugia malayi jmjC domain containing protein 0.0031 0.0079 0.0079
Schistosoma mansoni sodium/chloride dependent transporter 0.002 0.0021 0.0038
Loa Loa (eye worm) hypothetical protein 0.006 0.0218 0.0218
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0034 0.0094 0.1129
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0154 0.0684 1
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0154 0.0684 0.1553
Schistosoma mansoni voltage-gated potassium channel 0.0016 0.0003 0.0005
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0033 0.0088 0.0048
Echinococcus granulosus patatin phospholipase domain containing protein 0.0021 0.0026 0.0047
Loa Loa (eye worm) hypothetical protein 0.0049 0.0164 0.0164
Brugia malayi putative neuropeptide receptor NPR1 0.006 0.0218 0.0218
Onchocerca volvulus 0.006 0.0218 0.4437
Brugia malayi Sodium:neurotransmitter symporter family protein 0.002 0.0021 0.0021
Echinococcus granulosus jumonji domain containing protein 0.0034 0.0092 0.0165
Echinococcus multilocularis rhodopsin orphan GPCR 0.006 0.0218 0.0392
Brugia malayi latrophilin 2 splice variant baaae 0.0171 0.0765 0.0765
Echinococcus multilocularis voltage gated potassium channel 0.0016 0.0003 0.0005
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0019 0.0018 0.0154
Toxoplasma gondii oxidoreductase, 2OG-Fe(II) oxygenase family protein 0.0041 0.0125 0.0282
Onchocerca volvulus 0.006 0.0218 0.4437
Echinococcus granulosus potassium voltage gated channel subfamily A 0.0061 0.0226 0.0405
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0154 0.0684 0.1229
Loa Loa (eye worm) hypothetical protein 0.006 0.0218 0.0218
Schistosoma mansoni vesicular amine transporter 0.0016 0.0003 0.0005
Trypanosoma cruzi Sphingosine kinase 0.0045 0.0145 0.1241
Trypanosoma cruzi Diacylglycerol kinase catalytic domain containing protein, putative 0.0045 0.0145 0.1241
Leishmania major protein kinase A regulatory subunit, putative 0.0021 0.0026 0.0223
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.006 0.0218 0.0392
Schistosoma mansoni neuropeptide receptor 0.006 0.0218 0.0392
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0034 0.0094 0.0168
Echinococcus multilocularis neuropeptide Y receptor 0.006 0.0218 0.0392
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0154 0.0684 0.0684
Trichomonas vaginalis calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0154 0.0684 1
Treponema pallidum catabolite gene activator (Crp) 0.0021 0.0026 0.0169
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0742 0.3578 0.3578
Schistosoma mansoni tar DNA-binding protein 0.0117 0.0499 0.0897
Brugia malayi glutathione reductase 0.0055 0.0195 0.0195
Echinococcus multilocularis rhodopsin orphan GPCR 0.006 0.0218 0.0392
Onchocerca volvulus 0.0041 0.0125 0.2534
Schistosoma mansoni cpg binding protein 0.0032 0.0084 0.015
Loa Loa (eye worm) hypothetical protein 0.006 0.0218 0.0218
Echinococcus multilocularis neuropeptide receptor 0.006 0.0218 0.0392
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.0021
Plasmodium falciparum diacylglycerol kinase, putative 0.0045 0.0145 0.2115
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0028 0.0062 0.0111
Schistosoma mansoni camp-dependent protein kinase type II regulatory subunit 0.0021 0.0026 0.0047
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0154 0.0684 0.1229
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0154 0.0684 1
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0041 0.0129 0.0129
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0034 0.0094 0.0094
Schistosoma mansoni cyclic nucleotide-gated ion channel 0.0021 0.0026 0.0047
Loa Loa (eye worm) hypothetical protein 0.0139 0.0608 0.0608
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.002 0.0021 0.0021
Schistosoma mansoni similar to Protein C20orf152 homolog 0.0021 0.0026 0.0047
Trypanosoma cruzi cyclic nucleotide phosphodiesterase 0.0154 0.0684 0.5884
Brugia malayi RE15519p 0.006 0.0218 0.0218
Echinococcus granulosus sex peptide receptor 0.006 0.0218 0.0392
Schistosoma mansoni tar DNA-binding protein 0.0117 0.0499 0.0897
Leishmania major protein kinase, putative 0.0021 0.0026 0.0223
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0043 0.0137 0.1175
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0034 0.0094 0.0168
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.006 0.0218 0.0218
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.006 0.0218 0.0218
Plasmodium falciparum cAMP-dependent protein kinase regulatory subunit 0.0021 0.0026 0.0386
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0154 0.0684 1
Schistosoma mansoni diacylglycerol kinase zeta iota 0.0045 0.0145 0.026
Onchocerca volvulus 0.006 0.0218 0.4437
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0146 0.0643 0.9375
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0142 0.0624 0.112
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0019 0.0018 0.0154
Echinococcus multilocularis high affinity cgmp specific 3' 5' cyclic 0.0154 0.0684 0.1229
Loa Loa (eye worm) hypothetical protein 0.0015 0.0001 0.0001
Schistosoma mansoni voltage-gated potassium channel 0.0034 0.0094 0.0168
Onchocerca volvulus 0.006 0.0218 0.4437
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0154 0.0684 1
Loa Loa (eye worm) TYRA-2 protein 0.006 0.0218 0.0218
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0154 0.0684 1
Plasmodium falciparum diacylglycerol kinase, putative 0.0045 0.0145 0.2115
Loa Loa (eye worm) hypothetical protein 0.1892 0.9241 0.9241
Onchocerca volvulus 0.006 0.0218 0.4437
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.002 0.0021 0.0038
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.002 0.0021 0.0038
Loa Loa (eye worm) beta-lactamase 0.0072 0.0278 0.0278
Loa Loa (eye worm) solute carrier family 6 member 4 0.0115 0.0492 0.0492
Loa Loa (eye worm) voltage-gated potassium channel 0.0016 0.0003 0.0003
Echinococcus granulosus rhodopsin orphan GPCR 0.006 0.0218 0.0392
Schistosoma mansoni sodium/chloride dependent transporter 0.0115 0.0492 0.0883
Loa Loa (eye worm) hypothetical protein 0.0072 0.0278 0.0278
Loa Loa (eye worm) jmjC domain-containing protein 0.0031 0.0079 0.0079
Mycobacterium ulcerans esterase/lipase LipP 0.0072 0.0278 0.0468
Loa Loa (eye worm) hypothetical protein 0.006 0.0218 0.0218
Echinococcus multilocularis lysine specific demethylase 5A 0.0029 0.007 0.0126
Echinococcus multilocularis hyperpolarization activated cyclic 0.0034 0.0094 0.0168
Trypanosoma brucei hypothetical protein, conserved 0.0072 0.0278 0.2386
Loa Loa (eye worm) hypothetical protein 0.006 0.0218 0.0218
Plasmodium falciparum phosphodiesterase gamma, putative 0.0154 0.0684 1
Echinococcus granulosus voltage gated potassium channel 0.0016 0.0003 0.0005
Onchocerca volvulus Alhambra homolog 0.0024 0.0045 0.0911
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0154 0.0684 1
Schistosoma mansoni hypothetical protein 0.0028 0.0062 0.0111
Onchocerca volvulus 0.006 0.0218 0.4437
Mycobacterium tuberculosis Conserved protein 0.0072 0.0278 0.0468
Loa Loa (eye worm) hypothetical protein 0.006 0.0218 0.0218
Entamoeba histolytica diacylglycerol kinase, putative 0.0045 0.0145 0.0151
Loa Loa (eye worm) hypothetical protein 0.0034 0.0094 0.0094
Schistosoma mansoni inositol monophosphatase 0.0029 0.0066 0.0118
Echinococcus granulosus potassium voltage gated channel protein 0.0016 0.0003 0.0005
Echinococcus granulosus neuropeptides capa receptor 0.006 0.0218 0.0392
Echinococcus multilocularis transfer RNA-Gly 0.0016 0.0003 0.0005
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0034 0.0094 0.0168
Brugia malayi Cyclic-nucleotide gated cation channel 0.0034 0.0094 0.0094
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0019 0.0018 0.0269
Echinococcus multilocularis thioredoxin glutathione reductase 0.0055 0.0195 0.035
Echinococcus multilocularis sodium and chloride dependent glycine 0.002 0.0021 0.0038
Leishmania major hypothetical protein, conserved 0.0072 0.0278 0.2386
Schistosoma mansoni neuropathy target esterase/swiss cheese-related protein 0.0021 0.0026 0.0047
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0145 0.1897
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0021 0.0026 0.0047
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0154 0.0684 1
Echinococcus granulosus high affinity cgmp specific 3' 5' cyclic 0.0154 0.0684 0.1229
Brugia malayi hypothetical protein 0.006 0.0218 0.0218
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0154 0.0684 0.5884
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0019 0.0018 0.0154
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0239 0.1101 0.1977
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0019 0.0018 0.0154
Echinococcus multilocularis cAMP dependent protein kinase type II regulatory 0.0021 0.0026 0.0047
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0072 0.0278 0.0468
Trypanosoma cruzi hypothetical protein, conserved 0.0154 0.0684 0.5884
Schistosoma mansoni hypothetical protein 0.0024 0.0045 0.008
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0044 0.0143 0.1228
Treponema pallidum catabolite gene activator 0.0021 0.0026 0.0169
Echinococcus multilocularis GPCR, family 2 0.0079 0.0314 0.0564
Trypanosoma cruzi hypothetical protein, conserved 0.0072 0.0278 0.2386
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.006 0.0218 0.0218
Plasmodium vivax diacylglycerol kinase, putative 0.0045 0.0145 0.2115
Brugia malayi Dopamine receptor 0.006 0.0218 0.0218
Echinococcus granulosus peregrin 0.0024 0.0045 0.008
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.006 0.0218 0.0392
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0072 0.0278 0.0468
Echinococcus multilocularis sodium and chloride dependent glycine 0.002 0.0021 0.0038
Schistosoma mansoni rhodopsin-like orphan GPCR 0.006 0.0218 0.0392
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0044 0.0143 0.0225
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0154 0.0684 0.1229
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0026 0.0051 0.0058
Brugia malayi Dopamine receptor protein 2 0.006 0.0218 0.0218
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.006 0.0218 0.0392
Plasmodium falciparum ataxin-2 like protein, putative 0.0015 0.0001 0.0008
Onchocerca volvulus 0.006 0.0218 0.4437
Onchocerca volvulus 0.006 0.0218 0.4437
Loa Loa (eye worm) hypothetical protein 0.006 0.0218 0.0218
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0154 0.0684 0.5884
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0035 0.0099 0.0847
Echinococcus granulosus voltage gated potassium channel 0.0049 0.0164 0.0295
Schistosoma mansoni camp-specific cyclic nucleotide phosphodiesterase 0.0154 0.0684 0.1229
Loa Loa (eye worm) hypothetical protein 0.0171 0.0765 0.0765
Echinococcus multilocularis serotonin receptor 0.006 0.0218 0.0392
Loa Loa (eye worm) calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase 0.0154 0.0684 0.0684
Mycobacterium ulcerans aldehyde dehydrogenase 0.0037 0.0106 0.0158
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0458 0.218 0.3894
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0154 0.0684 1
Plasmodium vivax amine transporter, putative 0.002 0.0021 0.031
Loa Loa (eye worm) hypothetical protein 0.006 0.0218 0.0218
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0068 0.0261 0.0469
Leishmania major cyclic nucleotide-binding protein-like protein 0.0021 0.0026 0.0223
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0154 0.0684 0.5884
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0033 0.0088 0.0158
Loa Loa (eye worm) hypothetical protein 0.006 0.0218 0.0218
Plasmodium falciparum glutathione reductase 0.0055 0.0195 0.2845
Trypanosoma brucei 2OG-Fe(II) oxygenase superfamily, putative 0.0041 0.0125 0.1068
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0034 0.0094 0.1129
Onchocerca volvulus Ceramide kinase 1 homolog 0.0045 0.0145 0.2944
Leishmania major cAMP-specific phosphodiesterase, putative 0.0154 0.0684 0.5884
Echinococcus granulosus sodium and chloride dependent glycine 0.002 0.0021 0.0038
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.0154 0.0684 0.1229
Loa Loa (eye worm) hypothetical protein 0.006 0.0218 0.0218
Plasmodium vivax phosphodiesterase gamma, putative 0.0154 0.0684 1
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0029 0.0066 0.0559
Trypanosoma brucei cAMP phosphodiesterase A, putative 0.0154 0.0684 0.5884
Mycobacterium tuberculosis Conserved protein 0.0072 0.0278 0.0468
Echinococcus multilocularis sphingosine kinase 1 0.1146 0.5568 1
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0037 0.0106 0.0191
Echinococcus granulosus dro:myosuppressin receptor 0.006 0.0218 0.0392
Schistosoma mansoni sodium/chloride dependent transporter 0.002 0.0021 0.0038
Brugia malayi Sodium:neurotransmitter symporter family protein 0.002 0.0021 0.0021
Mycobacterium tuberculosis Probable oxidoreductase 0.0139 0.0609 0.1064
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0251 0.1163 1
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0026 0.0051 0.0419
Onchocerca volvulus 0.0115 0.0492 1
Onchocerca volvulus 0.006 0.0218 0.4437
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0154 0.0684 0.1229
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0154 0.0684 0.1229
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0154 0.0684 1
Echinococcus multilocularis potassium voltage gated channel protein 0.0061 0.0226 0.0405
Brugia malayi diacylglycerol kinase 0.0045 0.0145 0.0145
Brugia malayi Probable 3',5'-cyclic phosphodiesterase T04D3.3, putative 0.0154 0.0684 0.0684
Onchocerca volvulus 0.0072 0.0278 0.5651
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0088 0.1047
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0029 0.0066 1
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0154 0.0684 0.1229
Plasmodium falciparum thioredoxin reductase 0.0055 0.0195 0.2845
Loa Loa (eye worm) hypothetical protein 0.0021 0.0026 0.0026
Loa Loa (eye worm) hypothetical protein 0.006 0.0218 0.0218
Echinococcus multilocularis cAMP dependent protein kinase type I beta 0.0021 0.0026 0.0047
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0154 0.0684 1
Mycobacterium tuberculosis Probable hydrolase 0.0072 0.0278 0.0468
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0154 0.0684 0.1553
Schistosoma mansoni opsin-like receptor 0.006 0.0218 0.0392
Schistosoma mansoni rhodopsin-like orphan GPCR 0.006 0.0218 0.0392
Echinococcus granulosus allatostatin A receptor 0.006 0.0218 0.0392
Schistosoma mansoni hypothetical protein 0.0021 0.0026 0.0047
Toxoplasma gondii tetratricopeptide repeat-containing protein 0.0041 0.0125 0.0282
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.006 0.0218 0.0392
Trypanosoma cruzi diacylglycerol kinase, putative 0.0045 0.0145 0.1241
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0079 0.0314 0.0314
Mycobacterium ulcerans beta-lactamase 0.0072 0.0278 0.0468
Trypanosoma cruzi hypothetical protein, conserved 0.0045 0.0145 0.1241
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.006 0.0218 0.4437
Trichomonas vaginalis conserved hypothetical protein 0.0154 0.0684 1
Mycobacterium ulcerans aldehyde dehydrogenase 0.0037 0.0106 0.0158
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0037 0.0109 0.0109
Loa Loa (eye worm) hypothetical protein 0.006 0.0218 0.0218
Echinococcus multilocularis rhodopsin orphan GPCR 0.006 0.0218 0.0392
Trichomonas vaginalis diacylglycerol kinase, zeta, iota, putative 0.0045 0.0145 0.1897
Brugia malayi beta-lactamase family protein 0.0072 0.0278 0.0278
Loa Loa (eye worm) hypothetical protein 0.006 0.0218 0.0218
Loa Loa (eye worm) CXXC zinc finger family protein 0.0032 0.0084 0.0084
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0154 0.0684 0.1229
Plasmodium vivax thioredoxin reductase, putative 0.0055 0.0195 0.2845
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0154 0.0684 0.1553
Leishmania major hypothetical protein, conserved 0.0154 0.0684 0.5884
Loa Loa (eye worm) hypothetical protein 0.006 0.0218 0.0218
Trichomonas vaginalis penicillin-binding protein, putative 0.0072 0.0278 0.3896
Toxoplasma gondii ABC1 family protein 0.0072 0.0278 0.063
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0154 0.0684 1
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0896 0.4338 0.779
Schistosoma mansoni biogenic amine (5HT) receptor 0.006 0.0218 0.0392
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0154 0.0684 1
Loa Loa (eye worm) hypothetical protein 0.006 0.0218 0.0218
Schistosoma mansoni voltage-gated potassium channel 0.0061 0.0226 0.0405
Trichomonas vaginalis diacylglycerol kinase, zeta, iota, putative 0.0045 0.0145 0.1897
Plasmodium vivax cyclic nucleotide phosphodiesterase, putative 0.0154 0.0684 1
Echinococcus granulosus hyperpolarization activated cyclic 0.0034 0.0094 0.0168
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.002 0.0021 0.3448
Loa Loa (eye worm) G-protein coupled receptor 0.006 0.0218 0.0218
Schistosoma mansoni protein tyrosine phosphatase non-receptor type nt1 0.0239 0.1101 0.1977
Leishmania major cAMP phosphodiesterase A, putative;with=GeneDB:LinJ18_V3.1100 0.0154 0.0684 0.5884
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0139 0.0609 1
Loa Loa (eye worm) cyclic AMP specific phosphodiesterase PDE4D5A 0.0742 0.3578 0.3578
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.0021 0.0026 0.0059
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.002 0.0021 0.0038
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0016 0.0003 0.0005
Echinococcus granulosus neuropeptide Y receptor 0.006 0.0218 0.0392
Echinococcus granulosus cAMP dependent protein kinase type II regulatory 0.0021 0.0026 0.0047
Loa Loa (eye worm) hypothetical protein 0.0154 0.0684 0.0684
Giardia lamblia CAMP-specific 3,5-cyclic phosphodiesterase 4B 0.0896 0.4338 1
Loa Loa (eye worm) hypothetical protein 0.0115 0.0492 0.0492
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.0021 0.0026 0.0059
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0044 0.0143 0.0225
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0021 0.0026 0.0059
Loa Loa (eye worm) RNA binding protein 0.0117 0.0499 0.0499
Schistosoma mansoni tar DNA-binding protein 0.0117 0.0499 0.0897
Echinococcus multilocularis rhodopsin orphan GPCR 0.006 0.0218 0.0392
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0154 0.0684 1
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0154 0.0684 0.1553
Schistosoma mansoni hypothetical protein 0.006 0.0218 0.0392
Loa Loa (eye worm) pigment dispersing factor receptor c 0.025 0.1154 0.1154
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0033 0.0088 0.0158
Loa Loa (eye worm) hypothetical protein 0.006 0.0218 0.0218
Trypanosoma brucei hypothetical protein, conserved 0.0154 0.0684 0.5884
Echinococcus granulosus Diacylglycerol kinase theta 0.0045 0.0145 0.026
Plasmodium vivax CAMP-dependent protein kinase regulatory subunit, putative 0.0021 0.0026 0.0386
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0154 0.0684 1
Mycobacterium tuberculosis Conserved protein 0.0021 0.0026 0.0014
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0021 0.0026 0.0047
Echinococcus multilocularis geminin 0.0097 0.0402 0.0722
Loa Loa (eye worm) hypothetical protein 0.006 0.0218 0.0218
Onchocerca volvulus 0.002 0.0021 0.0431
Chlamydia trachomatis cAMP-dependent protein kinase regulatory subunit 0.0021 0.0026 1
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0034 0.0094 0.0094
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0115 0.0492 0.0492
Leishmania major protein kinase, putative 0.0021 0.0026 0.0223
Schistosoma mansoni inositol monophosphatase 0.0029 0.0066 0.0118
Loa Loa (eye worm) hypothetical protein 0.0033 0.0088 0.0088
Schistosoma mansoni myosin xvIII 0.006 0.0218 0.0392
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0072 0.0278 0.0499
Leishmania major hypothetical protein, conserved 0.0021 0.0026 0.0223
Echinococcus multilocularis orexin receptor type 2 0.006 0.0218 0.0392
Brugia malayi G-protein coupled receptor 0.006 0.0218 0.0218
Echinococcus granulosus inositol monophosphatase 1 0.0029 0.0066 0.0118
Brugia malayi Sodium:neurotransmitter symporter family protein 0.002 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0183 0.0825 0.0825
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0044 0.0143 0.0257
Echinococcus granulosus uncharacterized sodium dependent transporter 0.002 0.0021 0.0038
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0154 0.0684 1
Schistosoma mansoni voltage-gated potassium channel 0.0174 0.0781 0.1402
Loa Loa (eye worm) PHD-finger family protein 0.0024 0.0045 0.0045
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0019 0.0018 0.0154
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0016 0.0003 0.0003
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.002 0.0021 0.0047
Loa Loa (eye worm) hypothetical protein 0.006 0.0218 0.0218
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0019 0.0018 0.0269
Echinococcus multilocularis fmrfamide receptor 0.006 0.0218 0.0392
Trypanosoma cruzi diacylglycerol kinase, putative 0.0045 0.0145 0.1241
Brugia malayi gonadotropin-releasing hormone receptor 2 0.006 0.0218 0.0218
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0154 0.0684 0.1553
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0021 0.0026 0.0047
Loa Loa (eye worm) G-protein coupled receptor 0.006 0.0218 0.0218
Schistosoma mansoni neuropeptide receptor 0.006 0.0218 0.0392
Loa Loa (eye worm) hypothetical protein 0.0021 0.0026 0.0026
Schistosoma mansoni jumonji domain containing protein 0.0063 0.0237 0.0425
Schistosoma mansoni rhodopsin-like orphan GPCR 0.006 0.0218 0.0392
Loa Loa (eye worm) hypothetical protein 0.006 0.0218 0.0218
Echinococcus granulosus cAMP dependent protein kinase regulatory 0.0021 0.0026 0.0047
Mycobacterium tuberculosis Probable esterase LipL 0.0072 0.0278 0.0468
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0037 0.0106 0.0158
Schistosoma mansoni amine GPCR 0.006 0.0218 0.0392
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0119 0.0511 0.439
Brugia malayi larval opioid receptor 0.006 0.0218 0.0218
Loa Loa (eye worm) hypothetical protein 0.006 0.0218 0.0218
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0896 0.4338 0.779
Mycobacterium tuberculosis Probable conserved transmembrane transport protein 0.0021 0.0026 0.0014
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0033 0.0088 0.0158
Echinococcus granulosus neuropeptide receptor A26 0.006 0.0218 0.0392
Schistosoma mansoni hypothetical protein 0.0079 0.0314 0.0564
Trypanosoma cruzi diacylglycerol kinase-like protein, putative 0.0045 0.0145 0.1241
Schistosoma mansoni camp-dependent protein kinase type II-alpha regulatory subunit 0.0021 0.0026 0.0047
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0021 0.0026 0.0047
Echinococcus multilocularis neuropeptide FF receptor 2 0.006 0.0218 0.0392
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0044 0.0143 0.0257
Echinococcus granulosus shaker cognate 0.0016 0.0003 0.0005
Brugia malayi RNA recognition motif domain containing protein 0.0117 0.0499 0.0499
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0033 0.0088 0.0754
Trichomonas vaginalis D-aminoacylase, putative 0.0072 0.0278 0.3896
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.006 0.0218 0.0392
Mycobacterium ulcerans hypothetical protein 0.0021 0.0026 0.0014
Echinococcus granulosus biogenic amine 5HT receptor 0.006 0.0218 0.0392
Echinococcus multilocularis jumonji domain containing protein 0.0034 0.0092 0.0165
Loa Loa (eye worm) hypothetical protein 0.006 0.0218 0.0218
Leishmania major sphingosine kinase A, B, putative 0.0045 0.0145 0.1241
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0119 0.0511 0.439
Echinococcus granulosus potassium voltage gated channel protein 0.0061 0.0226 0.0405
Schistosoma mansoni rhodopsin-like orphan GPCR 0.006 0.0218 0.0392
Echinococcus multilocularis beta LACTamase domain containing family member 0.0072 0.0278 0.0499
Echinococcus multilocularis neuropeptide s receptor 0.006 0.0218 0.0392
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0154 0.0684 1
Echinococcus granulosus rhodopsin orphan GPCR 0.006 0.0218 0.0392
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0079 0.0314 0.0564
Plasmodium falciparum thioredoxin reductase 0.0019 0.0018 0.0269
Schistosoma mansoni voltage-gated potassium channel 0.0174 0.0781 0.1402
Loa Loa (eye worm) diacylglycerol kinase 2 0.0045 0.0145 0.0145
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0154 0.0684 0.5884
Trypanosoma cruzi cAMP response protein 1, putative 0.0021 0.0026 0.0223
Schistosoma mansoni serine/threonine protein kinase 0.0021 0.0026 0.0047
Schistosoma mansoni lipoxygenase 0.0043 0.0135 0.0243
Schistosoma mansoni biogenic amine (dopamine) receptor 0.006 0.0218 0.0392
Loa Loa (eye worm) hypothetical protein 0.006 0.0218 0.0218
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.006 0.0218 0.0218
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0019 0.0018 0.0154
Toxoplasma gondii diacylglycerol kinase accessory domain (presumed) domain-containing protein 0.0045 0.0145 0.0327
Giardia lamblia CAMP-dependent protein kinase regulatory chain 0.0021 0.0026 0.0019
Brugia malayi G-protein coupled receptor 0.006 0.0218 0.0218
Loa Loa (eye worm) hypothetical protein 0.006 0.0218 0.0218
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0034 0.0094 0.0168
Echinococcus granulosus neuropeptide receptor 0.006 0.0218 0.0392
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0049 0.0164 0.0295
Loa Loa (eye worm) hypothetical protein 0.0072 0.0278 0.0278
Loa Loa (eye worm) jmjC domain-containing protein 0.005 0.0172 0.0172
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.006 0.0218 0.0392
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0125 0.054 0.094
Schistosoma mansoni camp-dependent rap1 guanine-nucleotide exchange factor 0.0021 0.0026 0.0047
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0043 0.0135 0.0243
Entamoeba histolytica hypothetical protein, conserved 0.1146 0.5568 1
Echinococcus granulosus rhodopsin orphan GPCR 0.006 0.0218 0.0392
Echinococcus granulosus high affinity cAMP specific 3'5' cyclic 0.0154 0.0684 0.1229
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.002 0.0021 0.0038
Schistosoma mansoni hypothetical protein 0.006 0.0218 0.0392
Schistosoma mansoni amine GPCR 0.006 0.0218 0.0392
Schistosoma mansoni voltage-gated potassium channel 0.0049 0.0164 0.0295
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0024 0.0045 0.008
Trichomonas vaginalis sphingosine kinase, putative 0.0045 0.0145 0.1897
Mycobacterium ulcerans transmembrane transport protein 0.0021 0.0026 0.0014
Mycobacterium tuberculosis Diacylglycerol kinase 0.0045 0.0145 0.0228
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0026 0.012
Brugia malayi Serotonin receptor 0.006 0.0218 0.0218
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0034 0.0094 0.0168
Plasmodium vivax diacylglycerol kinase, putative 0.0045 0.0145 0.2115
Brugia malayi Inositol-1 0.0029 0.0066 0.0066
Schistosoma mansoni hypothetical protein 0.0079 0.0314 0.0564
Loa Loa (eye worm) hypothetical protein 0.006 0.0218 0.0218
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0154 0.0684 1
Echinococcus granulosus fmrfamide receptor 0.006 0.0218 0.0392
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.002 0.0021 0.0038
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0154 0.0684 1
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.0021
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0019 0.0018 0.0154
Echinococcus multilocularis potassium voltage gated channel protein 0.0016 0.0003 0.0005
Echinococcus multilocularis neuropeptide Y receptor 0.006 0.0218 0.0392
Loa Loa (eye worm) hypothetical protein 0.0154 0.0684 0.0684
Echinococcus multilocularis serotonin receptor 0.006 0.0218 0.0392
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0019 0.0018 0.0154
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0125 0.054 0.8821
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.0021
Echinococcus multilocularis PHD finger protein rhinoceros 0.0024 0.0045 0.008
Brugia malayi hypothetical protein 0.006 0.0218 0.0218
Loa Loa (eye worm) norepinephrine transporter 0.0115 0.0492 0.0492
Trichomonas vaginalis bmru protein, putative 0.0045 0.0145 0.1897
Schistosoma mansoni biogenic amine (dopamine) receptor 0.006 0.0218 0.0392
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.0154 0.0684 0.1229
Brugia malayi Eye-specific diacylglycerol kinase 0.0045 0.0145 0.0145
Echinococcus multilocularis neuropeptides capa receptor 0.006 0.0218 0.0392
Brugia malayi hypothetical protein 0.006 0.0218 0.0218
Echinococcus granulosus rhodopsin orphan GPCR 0.006 0.0218 0.0392
Plasmodium vivax hypothetical protein, conserved 0.0024 0.0045 0.0655
Brugia malayi Thioredoxin reductase 0.0055 0.0195 0.0195
Echinococcus multilocularis Diacylglycerol kinase zeta 0.0045 0.0145 0.026
Brugia malayi Calcitonin receptor-like protein seb-1 0.025 0.1154 0.1154
Echinococcus granulosus sodium and chloride dependent glycine 0.002 0.0021 0.0038
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0033 0.0088 0.0754
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0154 0.0684 1
Echinococcus multilocularis neuropeptide receptor 0.006 0.0218 0.0392
Brugia malayi cAMP-dependent protein kinase regulatory chain, putative 0.0021 0.0026 0.0026
Echinococcus multilocularis patatin phospholipase domain containing protein 0.0021 0.0026 0.0047
Echinococcus multilocularis peregrin 0.0024 0.0045 0.008
Schistosoma mansoni hypothetical protein 0.0079 0.0314 0.0564
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0019 0.0018 0.0033
Leishmania major trypanothione reductase 0.0055 0.0195 0.167
Loa Loa (eye worm) hypothetical protein 0.0329 0.1545 0.1545
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.006 0.0218 0.0392
Echinococcus multilocularis allatostatin A receptor 0.006 0.0218 0.0392
Brugia malayi follicle stimulating hormone receptor 0.006 0.0218 0.0218
Treponema pallidum sodium- and chloride- dependent transporter 0.0115 0.0492 1
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0154 0.0684 1
Schistosoma mansoni diacylglycerol kinase theta 0.0045 0.0145 0.026
Echinococcus granulosus neuropeptide Y receptor 0.006 0.0218 0.0392
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0154 0.0684 0.1553
Schistosoma mansoni growth hormone secretagogue receptor 0.006 0.0218 0.0392
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.091 0.4405 1
Loa Loa (eye worm) eye-specific diacylglycerol kinase 0.0045 0.0145 0.0145
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0034 0.0094 0.0168
Echinococcus granulosus acylglycerol kinase mitochondrial 0.0045 0.0145 0.026
Schistosoma mansoni camp-dependent protein kinase type I-beta regulatory subunit 0.0021 0.0026 0.0047
Trypanosoma cruzi protein kinase A regulatory subunit 0.0021 0.0026 0.0223
Echinococcus granulosus cGMP dependent protein kinase 0.0021 0.0026 0.0047
Schistosoma mansoni tar DNA-binding protein 0.0117 0.0499 0.0897
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0035 0.0099 0.0847
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0016 0.0003 0.0005
Brugia malayi Serotonin/octopamine receptor family protein 7 0.006 0.0218 0.0218
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.006 0.0218 0.0218
Trypanosoma brucei cAMP binding protein, putative 0.0021 0.0026 0.0223
Echinococcus granulosus rhodopsin orphan GPCR 0.006 0.0218 0.0392
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0142 0.0624 0.112
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0029 0.0066 0.0707
Trichomonas vaginalis sphingosine kinase, putative 0.0045 0.0145 0.1897
Schistosoma mansoni biogenic amine receptor 0.006 0.0218 0.0392
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0154 0.0684 0.0684
Schistosoma mansoni biogenic amine receptor 0.006 0.0218 0.0392
Echinococcus granulosus somatostatin receptor 0.006 0.0218 0.0392
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.006 0.0218 0.0392
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0154 0.0684 0.1553
Echinococcus multilocularis microtubule associated protein 2 0.0419 0.1986 0.3566
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0034 0.0094 0.0168
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0159 0.071 0.1275
Echinococcus multilocularis shaker cognate 0.0016 0.0003 0.0005
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.002 0.0021 0.0038
Trypanosoma cruzi hypothetical protein, conserved 0.0154 0.0684 0.5884
Onchocerca volvulus 0.006 0.0218 0.4437
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0072 0.0278 0.0468
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0239 0.1101 0.1101
Echinococcus multilocularis prolyl 4 hydroxylase subunit alpha 1 0.0041 0.0125 0.0224
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0033 0.0088 0.0161
Echinococcus granulosus survival motor neuron protein 1 0.0183 0.0825 0.1482
Toxoplasma gondii diacylglycerol kinase catalytic domain-containing protein 0.0045 0.0145 0.0327
Trypanosoma cruzi diacylglycerol kinase-like protein, putative 0.0045 0.0145 0.1241
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0029 0.0066 0.0085
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0021 0.0026 0.012
Loa Loa (eye worm) hypothetical protein 0.0024 0.0045 0.0045
Onchocerca volvulus 0.006 0.0218 0.4437
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0033 0.0088 0.0158
Echinococcus multilocularis potassium voltage gated channel subfamily C 0.0016 0.0003 0.0005
Loa Loa (eye worm) hypothetical protein 0.006 0.0218 0.0218
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0049 0.0164 0.0295
Onchocerca volvulus 0.0032 0.0084 0.1698
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0154 0.0684 1
Toxoplasma gondii thioredoxin reductase 0.0055 0.0195 0.0441
Loa Loa (eye worm) cAMP-dependent protein kinase regulatory subunit 0.0021 0.0026 0.0026
Leishmania major hypothetical protein, conserved 0.0021 0.0026 0.0223
Plasmodium vivax glutathione reductase, putative 0.0055 0.0195 0.2845
Loa Loa (eye worm) hypothetical protein 0.006 0.0218 0.0218

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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