Detailed information for compound 1044800

Basic information

Technical information
  • TDR Targets ID: 1044800
  • Name: 4-nitro-7-piperazin-1-yl-2,1,3-benzoxadiazole
  • MW: 249.226 | Formula: C10H11N5O3
  • H donors: 1 H acceptors: 4 LogP: 0.47 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: [O-][N+](=O)c1ccc(c2c1non2)N1CCNCC1
  • InChi: 1S/C10H11N5O3/c16-15(17)8-2-1-7(9-10(8)13-18-12-9)14-5-3-11-4-6-14/h1-2,11H,3-6H2
  • InChiKey: MVLWYDGJBGPXOL-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 4-nitro-7-(1-piperazinyl)-2,1,3-benzoxadiazole
  • 4-nitro-7-piperazin-1-yl-benzofurazan
  • 4-Nitro-7-piperazinobenzofurazan
  • 92614_FLUKA

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0171 0.0161 0.0161
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0294 0.054 0.0776
Echinococcus multilocularis cyclin dependent kinase 9 0.0178 0.0182 0.0182
Schistosoma mansoni protein kinase 0.0183 0.0198 0.0426
Schistosoma mansoni serine/threonine protein kinase 0.0513 0.1219 0.2615
Schistosoma mansoni serine/threonine protein kinase 0.0189 0.0215 0.0461
Schistosoma mansoni serine/threonine protein kinase 0.042 0.0931 0.1998
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0258 0.0429 0.0617
Loa Loa (eye worm) hypothetical protein 0.0418 0.0924 0.1328
Brugia malayi Temporarily assigned gene name protein 59 0.0124 0.0015 0.0022
Echinococcus multilocularis phosphorylase kinase gamma subunit 0.0199 0.0246 0.0246
Brugia malayi Tyrosine-protein kinase abl-1 0.0547 0.1323 0.1902
Entamoeba histolytica protein kinase , putative 0.0293 0.0537 0.4408
Echinococcus granulosus cyclin dependent kinase 1 0.024 0.0375 0.0519
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.024 0.0375 0.0539
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0252 0.0412 0.0412
Entamoeba histolytica protein kinase, putative 0.0171 0.0159 0.1304
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.031 0.059 0.1265
Loa Loa (eye worm) hypothetical protein 0.0265 0.0452 0.065
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0273 0.0476 0.0476
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0309 0.0586 0.0586
Echinococcus multilocularis expressed conserved protein 0.017 0.0158 0.0158
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0293 0.0537 0.0744
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0488 0.1142 1
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0543 0.1311 0.1311
Trypanosoma cruzi polo-like protein kinase, putative 0.021 0.028 0.0823
Brugia malayi Kinase associated domain 1 family protein 0.013 0.0034 0.0048
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0221 0.0316 0.2766
Echinococcus granulosus titin 0.0157 0.0118 0.0163
Brugia malayi serine/threonine-protein kinase PAK 7 0.082 0.217 0.3118
Onchocerca volvulus Serine\/threonine kinase homolog 0.0199 0.0246 0.0188
Trypanosoma cruzi casein kinase, putative 0.0258 0.0429 0.1268
Echinococcus granulosus mitogen activated protein kinase 11 0.1203 0.3354 0.4644
Brugia malayi Variant SH3 domain containing protein 0.0136 0.0052 0.0075
Echinococcus multilocularis casein kinase I alpha 0.0258 0.0429 0.0429
Schistosoma mansoni tyrosine kinase 0.0596 0.1477 0.3168
Loa Loa (eye worm) hypothetical protein 0.0415 0.0917 0.1318
Giardia lamblia Kinase, AGC PKA 0.0309 0.0586 0.5115
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.0742 0.1929 0.1929
Entamoeba histolytica protein kinase domain containing protein 0.0449 0.1022 0.838
Echinococcus multilocularis serine threonine protein kinase 0.0333 0.0662 0.0662
Brugia malayi Hr1 repeat family protein 0.0939 0.254 0.3649
Schistosoma mansoni protein kinase 0.0293 0.0537 0.1153
Brugia malayi hypothetical protein 0.0182 0.0195 0.028
Brugia malayi Protein kinase domain 0.0171 0.0161 0.0231
Schistosoma mansoni vav2 0.0213 0.029 0.0622
Entamoeba histolytica cell division protein kinase 2, putative 0.0256 0.0424 0.3475
Schistosoma mansoni tyrosine kinase 0.103 0.2821 0.605
Plasmodium falciparum calcium-dependent protein kinase 5 0.0273 0.0476 0.4148
Plasmodium falciparum calcium-dependent protein kinase 2 0.0273 0.0476 0.4148
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0172 0.0162 0.0233
Plasmodium falciparum calcium-dependent protein kinase 4 0.0273 0.0476 0.4148
Echinococcus granulosus tyrosine protein kinase Lyn 0.0615 0.1536 0.2126
Brugia malayi Protein kinase domain containing protein 0.0121 0.0005 0.0007
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.1203 0.3354 0.482
Brugia malayi Protein kinase domain containing protein 0.0246 0.0392 0.0564
Plasmodium vivax protein kinase, putative 0.0125 0.0019 0.0123
Brugia malayi serine/threonine-protein kinase 6 0.0293 0.0537 0.0772
Trichomonas vaginalis CAMK family protein kinase 0.021 0.028 0.2456
Plasmodium vivax unspecified product 0.0137 0.0056 0.0446
Entamoeba histolytica protein kinase, putative 0.0513 0.1219 1
Loa Loa (eye worm) hypothetical protein 0.0182 0.0195 0.028
Entamoeba histolytica PH domain containing protein kinase, putative 0.0329 0.0649 0.5324
Giardia lamblia Kinase, NEK 0.0172 0.0163 0.139
Schistosoma mansoni tyrosine kinase 0.0628 0.1575 0.3377
Giardia lamblia Kinase, AGC AKT 0.0404 0.088 0.7703
Entamoeba histolytica protein kinase, putative 0.0449 0.1022 0.838
Onchocerca volvulus 0.0319 0.062 0.0734
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0273 0.0476 0.0476
Trichomonas vaginalis CAMK family protein kinase 0.0282 0.0503 0.4406
Schistosoma mansoni tyrosine kinase 0.1625 0.4662 1
Schistosoma mansoni serine/threonine protein kinase 0.0172 0.0162 0.0348
Toxoplasma gondii histone kinase SNF1, putative 0.0172 0.0162 0.1386
Brugia malayi cell division control protein 2 homolog 0.024 0.0375 0.0539
Schistosoma mansoni serine/threonine protein kinase 0.0199 0.0246 0.0528
Trichomonas vaginalis CAMK family protein kinase 0.0273 0.0476 0.4172
Echinococcus multilocularis calcium dependent protein kinase 0.02 0.0252 0.0252
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0273 0.0476 0.4148
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0543 0.1311 0.1311
Loa Loa (eye worm) CAMK/PIM protein kinase 0.1022 0.2796 0.4017
Echinococcus granulosus serine:threonine protein kinase N2 0.0646 0.163 0.2257
Schistosoma mansoni serine/threonine protein kinase 0.0144 0.0078 0.0166
Echinococcus granulosus tyrosine kinase 0.0457 0.1047 0.1449
Schistosoma mansoni protein kinase 0.0226 0.0332 0.0711
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0293 0.0537 0.4686
Brugia malayi Egg laying defective protein 4 0.017 0.0158 0.0227
Brugia malayi Protein kinase domain containing protein 0.1022 0.2796 0.4017
Echinococcus granulosus protein kinase c epsilon type 0.0373 0.0785 0.1087
Echinococcus multilocularis casein kinase I delta 0.0258 0.0429 0.0429
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0191 0.0224 0.0224
Echinococcus multilocularis protein kinase c iota type 0.0451 0.1028 0.1028
Echinococcus multilocularis cyclin dependent kinase 9 0.0162 0.0133 0.0133
Schistosoma mansoni serine/threonine protein kinase 0.1387 0.3925 0.8419
Loa Loa (eye worm) sex muscle abnormal protein 5 0.02 0.025 0.036
Echinococcus granulosus tyrosine protein kinase Fyn 0.0543 0.1311 0.1815
Leishmania major casein kinase, putative 0.0258 0.0429 0.1268
Brugia malayi Sex muscle abnormal protein 5 0.02 0.025 0.036
Loa Loa (eye worm) TK/ABL protein kinase 0.0842 0.2238 0.3216
Loa Loa (eye worm) TK/FER protein kinase 0.0225 0.0329 0.0472
Echinococcus granulosus serine threonine protein kinase nrc 0.0191 0.0224 0.031
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0455 0.1039 0.1492
Trichomonas vaginalis STE family protein kinase 0.0122 0.0009 0.0083
Trichomonas vaginalis CMGC family protein kinase 0.0175 0.0171 0.15
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0842 0.2238 0.2238
Schistosoma mansoni serine/threonine protein kinase 0.0203 0.0258 0.0554
Schistosoma mansoni serine/threonine protein kinase 0.0172 0.0162 0.0348
Echinococcus granulosus Vam6:Vps39 protein 0.031 0.059 0.0817
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0294 0.054 0.054
Entamoeba histolytica serine/threonine protein kinase, putative 0.021 0.028 0.2299
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0183 0.0198 0.1704
Brugia malayi Protein kinase domain containing protein 0.104 0.285 0.4096
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0457 0.1047 0.1449
Echinococcus multilocularis insulin receptor 0.0712 0.1836 0.1836
Echinococcus multilocularis protein tyrosine kinase 0.1625 0.4662 0.4662
Schistosoma mansoni serine/threonine protein kinase 0.0625 0.1565 0.3357
Echinococcus multilocularis serine:threonine protein kinase receptor R3 0.0286 0.0516 0.0516
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0301 0.0562 0.0779
Trichomonas vaginalis AGC family protein kinase 0.0433 0.0972 0.8511
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.0172 0.0162 0.047
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0273 0.0476 0.4148
Echinococcus multilocularis leucine rich repeat serine:threonine protein 0.0189 0.0217 0.0217
Echinococcus multilocularis expressed protein 0.0121 0.0005 0.0005
Loa Loa (eye worm) CMGC/CDK/CDK8 protein kinase 0.0593 0.1466 0.2106
Echinococcus granulosus c src tyrosine kinase 0.0311 0.0593 0.0821
Echinococcus multilocularis serine:threonine protein kinase 0.0193 0.0229 0.0229
Brugia malayi Serine/threonine-protein kinase SULU 0.1387 0.3925 0.564
Brugia malayi Protein kinase domain containing protein 0.2078 0.6064 0.8714
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0258 0.0429 0.0617
Trypanosoma brucei casein kinase I, isoform 2 0.0258 0.0429 0.1268
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0212 0.0287 0.0842
Echinococcus multilocularis dual specificity 0.0175 0.0171 0.0171
Giardia lamblia Kinase, PLK 0.021 0.028 0.2424
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0309 0.0586 0.0812
Loa Loa (eye worm) AGC/NDR protein kinase 0.0294 0.054 0.0776
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.1387 0.3925 0.3925
Echinococcus granulosus activated cdc42 kinase 1 0.0604 0.1502 0.208
Plasmodium falciparum protein serine/threonine kinase-1 0.0488 0.1142 1
Echinococcus granulosus protein kinase 0.043 0.0961 0.1331
Brugia malayi Protein kinase domain containing protein 0.0225 0.0329 0.0472
Brugia malayi P38 map kinase family protein 2 0.1203 0.3354 0.482
Trichomonas vaginalis CAMK family protein kinase 0.0172 0.0162 0.1423
Echinococcus multilocularis tyrosine kinase 0.0225 0.0329 0.0329
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.047 0.1086 0.156
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0187 0.021 0.1725
Schistosoma mansoni tyrosine kinase 0.0712 0.1836 0.3937
Giardia lamblia Kinase, STE STE20 0.0171 0.0161 0.1371
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.024 0.0375 0.0539
Echinococcus multilocularis cGMP dependent protein kinase 1 0.017 0.0158 0.0158
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0191 0.0224 0.1927
Loa Loa (eye worm) hypothetical protein 0.0397 0.0861 0.1237
Entamoeba histolytica protein kinase domain containing protein 0.0513 0.1219 1
Schistosoma mansoni tyrosine kinase 0.0301 0.0562 0.1206
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.1022 0.2796 0.2796
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0488 0.1142 0.3393
Brugia malayi Protein kinase domain containing protein 0.0391 0.0843 0.1211
Brugia malayi Protein kinase domain containing protein 0.0234 0.0355 0.0511
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0382 0.0815 0.0815
Loa Loa (eye worm) casein kinase 0.0173 0.0168 0.0241
Schistosoma mansoni tyrosine kinase 0.0712 0.1836 0.3937
Loa Loa (eye worm) TK/FER protein kinase 0.0225 0.0329 0.0472
Loa Loa (eye worm) hypothetical protein 0.0135 0.0049 0.007
Schistosoma mansoni serine/threonine protein kinase 0.0175 0.0171 0.0367
Echinococcus multilocularis cyclin dependent kinase 19 0.0593 0.1466 0.1466
Trichomonas vaginalis CAMK family protein kinase 0.0172 0.0162 0.1423
Loa Loa (eye worm) hypothetical protein 0.0487 0.1139 0.1637
Schistosoma mansoni serine/threonine protein kinase 0.021 0.028 0.0601
Loa Loa (eye worm) hypothetical protein 0.0172 0.0162 0.0233
Loa Loa (eye worm) hypothetical protein 0.031 0.059 0.0848
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0596 0.1477 0.1477
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0171 0.0161 0.0161
Brugia malayi Protein kinase domain containing protein 0.0472 0.1093 0.1571
Entamoeba histolytica protein kinase, putative 0.0171 0.0159 0.1304
Brugia malayi Protein kinase domain containing protein 0.0226 0.0332 0.0477
Trichomonas vaginalis CAMK family protein kinase 0.0172 0.0162 0.1423
Entamoeba histolytica protein kinase domain containing protein 0.0162 0.0133 0.109
Schistosoma mansoni vam6/vps39 related 0.031 0.059 0.1265
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0121 0.0007 0.0006
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.1224 0.3422 0.4917
Echinococcus granulosus serine/threonine protein kinase 0.0212 0.0287 0.0397
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0309 0.0586 0.0586
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0135 0.0049 0.007
Schistosoma mansoni serine/threonine protein kinase 0.1022 0.2796 0.5996
Giardia lamblia Kinase, NEK 0.0172 0.0163 0.139
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.017 0.0158 0.1349
Schistosoma mansoni serine/threonine protein kinase 0.0411 0.0903 0.1938
Brugia malayi Protein kinase domain containing protein 0.0488 0.1142 0.164
Echinococcus multilocularis activated cdc42 kinase 1 0.0604 0.1502 0.1502
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0456 0.1042 0.1498
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0127 0.0023 0.0049
Entamoeba histolytica PH domain containing protein kinase, putative 0.0212 0.0287 0.2352
Entamoeba histolytica serine/threonine protein kinase STE20, putative 0.0122 0.0009 0.0078
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0323 0.0632 0.0875
Entamoeba histolytica serine/threonine-protein kinase 3, putative 0.0122 0.0009 0.0078
Onchocerca volvulus 0.0281 0.0501 0.056
Schistosoma mansoni tyrosine kinase 0.0311 0.0593 0.1273
Onchocerca volvulus 0.0354 0.0726 0.0889
Giardia lamblia Kinase, CMGC MAPK 0.0121 0.0007 0.0017
Echinococcus multilocularis cyclin dependent kinase 1 0.024 0.0375 0.0375
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0193 0.0227 0.0227
Schistosoma mansoni protein kinase 0.0324 0.0635 0.1362
Echinococcus granulosus N chimaerin 0.0193 0.0227 0.0314
Onchocerca volvulus 0.2367 0.6959 1
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0234 0.0355 0.0511
Brugia malayi Variant SH3 domain containing protein 0.0193 0.0227 0.0326
Entamoeba histolytica protein kinase, putative 0.0273 0.0476 0.3906
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0382 0.0815 0.1128
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.031 0.059 0.1747
Schistosoma mansoni ephrin receptor 0.0172 0.0165 0.0353
Schistosoma mansoni protein kinase 0.0171 0.0161 0.0345
Entamoeba histolytica protein kinase, putative 0.0121 0.0005 0.004
Trichomonas vaginalis CMGC family protein kinase 0.024 0.0375 0.3286
Entamoeba histolytica protein kinase, putative 0.0171 0.0161 0.1318
Loa Loa (eye worm) CMGC/CDK/CDK7 protein kinase 0.0227 0.0335 0.0481
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0121 0.0007 0.0006
Onchocerca volvulus 0.0185 0.0205 0.0127
Loa Loa (eye worm) hypothetical protein 0.0409 0.0898 0.129
Loa Loa (eye worm) TK/FER protein kinase 0.0225 0.0329 0.0472
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0293 0.0537 0.4408
Brugia malayi map kinase activated protein kinase protein 2 0.042 0.0931 0.1338
Trypanosoma cruzi casein kinase, putative 0.0258 0.0429 0.1268
Loa Loa (eye worm) hypothetical protein 0.0409 0.0898 0.129
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.0175 0.0171 0.0246
Brugia malayi RhoGAP domain containing protein 0.0193 0.0227 0.0326
Echinococcus granulosus casein kinase I alpha 0.0258 0.0429 0.0595
Schistosoma mansoni cell adhesion molecule 0.0307 0.0582 0.1248
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.0288 0.0522 0.0751
Loa Loa (eye worm) AGC/PKA protein kinase 0.0309 0.0586 0.0842
Trichomonas vaginalis CMGC family protein kinase 0.0137 0.0056 0.0486
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0157 0.0118 0.0169
Echinococcus granulosus activated cdc42 kinase 1 0.0604 0.1502 0.208
Echinococcus granulosus serine:threonine protein kinase 0.0193 0.0229 0.0317
Echinococcus granulosus cyclin dependent kinase 9 0.0178 0.0182 0.0251
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0353 0.0724 0.0724
Schistosoma mansoni nephrin 0.0127 0.0023 0.0049
Onchocerca volvulus 0.0418 0.0924 0.1179
Trichomonas vaginalis AGC family protein kinase 0.0293 0.0537 0.4708
Leishmania major protein kinase, putative 0.0488 0.1142 0.3393
Echinococcus granulosus serine:threonine protein kinase 0.0193 0.0229 0.0317
Schistosoma mansoni serine/threonine protein kinase 0.0227 0.0335 0.0718
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0543 0.1311 0.1311
Brugia malayi cyclin-dependent kinase 9 0.0162 0.0133 0.0191
Echinococcus granulosus mitogen activated protein kinase 0.0121 0.0007 0.0009
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.104 0.285 0.3946
Loa Loa (eye worm) TKL/STKR/TYPE2 protein kinase 0.0255 0.0419 0.0602
Loa Loa (eye worm) hypothetical protein 0.0127 0.0023 0.0033
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0121 0.0007 0.0006
Schistosoma mansoni protein kinase 0.1258 0.3525 0.7561
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0127 0.0023 0.0033
Brugia malayi Protein kinase domain containing protein 0.0294 0.054 0.0776
Echinococcus granulosus protein kinase C gamma type 0.0333 0.0662 0.0917
Entamoeba histolytica protein kinase, putative 0.0433 0.0972 0.7968
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0543 0.1311 0.1311
Echinococcus multilocularis neuroglian 0.0324 0.0634 0.0634
Echinococcus granulosus serine:threonine kinase SAD 1 0.0172 0.0162 0.0225
Loa Loa (eye worm) STE/STE7/MEK1 protein kinase 0.0367 0.0768 0.1103
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0543 0.1311 0.1311
Trichomonas vaginalis STE family protein kinase 0.0172 0.0163 0.1426
Echinococcus multilocularis aurora kinase A 0.0293 0.0537 0.0537
Brugia malayi hypothetical protein 0.0225 0.0329 0.0472
Loa Loa (eye worm) TK/FER protein kinase 0.0225 0.0329 0.0472
Loa Loa (eye worm) hypothetical protein 0.0309 0.0586 0.0842
Schistosoma mansoni serine/threonine protein kinase 0.0507 0.12 0.2574
Schistosoma mansoni protein kinase 0.0258 0.0429 0.0921
Entamoeba histolytica protein kinase domain containing protein 0.0449 0.1022 0.838
Echinococcus multilocularis 0.0415 0.0917 0.0917
Brugia malayi Protein kinase domain containing protein 0.2367 0.6959 1
Brugia malayi Cam kinase protein 1 0.0273 0.0476 0.0684
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0122 0.0009 0.0014
Trypanosoma brucei cdc2-related kinase 1 0.024 0.0375 0.1105
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.0175 0.0171 0.0246
Echinococcus multilocularis dual specificity mitogen activated protein 0.0367 0.0768 0.0768
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0293 0.0537 0.0537
Echinococcus multilocularis dual specificity 0.0175 0.0171 0.0171
Schistosoma mansoni kinase 0.0162 0.0133 0.0285
Echinococcus granulosus cyclin dependent kinase 19 0.0593 0.1466 0.2029
Echinococcus granulosus tyrosine kinase 0.0225 0.0329 0.0455
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.0175 0.0171 0.1464
Trichomonas vaginalis AGC family protein kinase 0.0135 0.0049 0.0426
Onchocerca volvulus 0.0225 0.0329 0.0308
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.1387 0.3925 0.564
Brugia malayi Protein kinase domain containing protein 0.0255 0.0419 0.0602
Trichomonas vaginalis CMGC family protein kinase 0.024 0.0375 0.3286
Schistosoma mansoni growth factor receptor-bound protein 0.02 0.025 0.0537
Echinococcus multilocularis epidermal growth factor receptor 0.0628 0.1575 0.1575
Schistosoma mansoni protein kinase 0.0183 0.0198 0.0426
Echinococcus granulosus mitogen activated protein kinase 14 0.1203 0.3354 0.4644
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0488 0.1142 0.3393
Leishmania major protein kinase, putative 0.0273 0.0476 0.1407
Trichomonas vaginalis CMGC family protein kinase 0.0121 0.0007 0.0059
Entamoeba histolytica protein kinase domain containing protein 0.0137 0.0056 0.0455
Echinococcus multilocularis tyrosine protein kinase Srms 0.0457 0.1047 0.1047
Schistosoma mansoni serine/threonine protein kinase 0.0258 0.0429 0.0921
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0596 0.1477 0.1477
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.018 0.0189 0.0189
Entamoeba histolytica protein kinase, putative 0.0293 0.0537 0.4408
Trypanosoma brucei cdc2-related kinase 3 0.024 0.0375 0.1105
Echinococcus granulosus cGMP dependent protein kinase 1 0.017 0.0158 0.0219
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0273 0.0476 0.4148
Schistosoma mansoni serine/threonine protein kinase 0.0294 0.054 0.1159
Schistosoma mansoni cell adhesion molecule 0.0127 0.0023 0.0049
Entamoeba histolytica tyrosin kinase, putative 0.0132 0.004 0.0324
Loa Loa (eye worm) hypothetical protein 0.0225 0.0329 0.0472
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0323 0.0632 0.0632
Echinococcus multilocularis casein kinase I alpha 0.0258 0.0429 0.0429
Loa Loa (eye worm) AGC/AKT protein kinase 0.0433 0.0972 0.1396
Trichomonas vaginalis CAMK family protein kinase 0.0225 0.0329 0.2882
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0456 0.1042 0.1443
Trichomonas vaginalis STE family protein kinase 0.0171 0.0161 0.1408
Loa Loa (eye worm) hypothetical protein 0.0406 0.0889 0.1278
Leishmania major mitogen-activated protein kinase kinase 5, putative;with=GeneDB:LmxM36.0860 0.0367 0.0768 0.2278
Echinococcus granulosus cGMP dependent protein kinase 0.017 0.0158 0.0219
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.0193 0.0229 0.0329
Brugia malayi Fibronectin type III domain containing protein 0.0265 0.0452 0.065
Loa Loa (eye worm) hypothetical protein 0.0252 0.0412 0.0592
Loa Loa (eye worm) hypothetical protein 0.02 0.025 0.036
Schistosoma mansoni serine/threonine protein kinase 0.017 0.0158 0.0339
Trypanosoma cruzi mitogen-activated protein kinase kinase 5 0.0367 0.0768 0.2278
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0488 0.1142 0.3393
Entamoeba histolytica hypothetical protein 0.0513 0.1219 1
Echinococcus granulosus growth factor receptor bound protein 2 0.0207 0.0271 0.0375
Schistosoma mansoni tyrosine kinase 0.0494 0.1161 0.249
Echinococcus granulosus cyclin dependent kinase 0.024 0.0375 0.0519
Echinococcus multilocularis c src tyrosine kinase 0.0311 0.0593 0.0593
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0985 0.268 0.3851
Loa Loa (eye worm) SRC-1 0.0543 0.1311 0.1884
Entamoeba histolytica protein kinase domain containing protein 0.0236 0.0361 0.2959
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0413 0.0909 0.1306
Entamoeba histolytica protein kinase domain containing protein 0.0175 0.0171 0.1405
Loa Loa (eye worm) hypothetical protein 0.0604 0.1502 0.2159
Schistosoma mansoni serine/threonine protein kinase 0.024 0.0375 0.0805
Loa Loa (eye worm) hypothetical protein 0.1797 0.5194 0.7464
Plasmodium falciparum glycogen synthase kinase 3 0.0449 0.1022 0.8947
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0183 0.0198 0.0578
Schistosoma mansoni tyrosine kinase 0.0543 0.1311 0.2812
Trypanosoma brucei mitogen-activated protein kinase kinase 5 0.0367 0.0768 0.2278
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0199 0.0247 0.0355
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0543 0.1311 0.1311
Loa Loa (eye worm) CMGC/DYRK/HIPK protein kinase 0.0236 0.0361 0.0519
Echinococcus granulosus roundabout 2 0.0379 0.0804 0.1113
Plasmodium vivax protein kinase Crk2 0.024 0.0375 0.3257
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.031 0.059 0.1265
Loa Loa (eye worm) TK/ALK protein kinase 0.2077 0.6062 0.8711
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0127 0.0023 0.0023
Schistosoma mansoni serine/threonine protein kinase 0.024 0.0375 0.0805
Schistosoma mansoni hypothetical protein 0.013 0.0034 0.0072
Entamoeba histolytica protein kinase domain containing protein 0.0183 0.0198 0.1628
Plasmodium vivax glycogen synthase kinase 3, putative 0.0449 0.1022 0.8947
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0323 0.0632 0.0632
Loa Loa (eye worm) hypothetical protein 0.044 0.0995 0.1429
Schistosoma mansoni protein kinase 0.104 0.285 0.6113
Schistosoma mansoni tyrosine kinase 0.0311 0.0593 0.1273
Echinococcus multilocularis serine:threonine protein kinase N2 0.0294 0.054 0.054
Schistosoma mansoni serine/threonine-protein kinase 0.0212 0.0287 0.0615
Trichomonas vaginalis CAMK family protein kinase 0.0152 0.01 0.0877
Trichomonas vaginalis CAMK family protein kinase 0.0172 0.0162 0.1423
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.021 0.028 0.0403
Giardia lamblia Kinase, CMGC GSK 0.0449 0.1022 0.8947
Onchocerca volvulus 0.031 0.059 0.069
Trypanosoma brucei SNF1-related protein kinases, putative 0.0172 0.0162 0.047
Echinococcus granulosus tyrosine protein kinase Srms 0.0618 0.1543 0.2136
Brugia malayi protein unc-22 0.0157 0.0118 0.0169
Schistosoma mansoni atypical protein kinase C 0.0457 0.1047 0.2245
Echinococcus multilocularis protein KINase family member (kin 25) 0.0301 0.0562 0.0562
Schistosoma mansoni protein kinase 0.0137 0.0056 0.0119
Echinococcus granulosus MAP kinase activated protein kinase 2 0.042 0.0931 0.129
Brugia malayi Protein kinase domain containing protein 0.0618 0.1544 0.2219
Echinococcus multilocularis serine:threonine protein kinase 0.0193 0.0229 0.0229
Schistosoma mansoni serine/threonine protein kinase 0.05 0.1178 0.2527
Echinococcus granulosus [G-protein-coupledreceptor] kinase 0.0416 0.092 0.1274
Brugia malayi hypothetical protein 0.0169 0.0156 0.0224
Onchocerca volvulus Tyrosine kinase homolog 0.1274 0.3577 0.5056
Plasmodium falciparum serine/threonine protein kinase KIN 0.0172 0.0162 0.1386
Echinococcus multilocularis tyrosine protein kinase shark 0.0431 0.0965 0.0965
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0191 0.0224 0.031
Entamoeba histolytica protein kinase, putative 0.0121 0.0005 0.004
Trichomonas vaginalis CK1 family protein kinase 0.0258 0.0429 0.3762
Schistosoma mansoni serine/threonine protein kinase 0.0354 0.0726 0.1557
Onchocerca volvulus 0.0158 0.012 0.0003
Brugia malayi Fes/CIP4 homology domain containing protein 0.0447 0.1015 0.1458
Onchocerca volvulus 0.0225 0.0329 0.0308
Echinococcus granulosus serine:threonine protein kinase PLK1 0.021 0.028 0.0388
Echinococcus multilocularis serine:threonine protein kinase 3 0.0288 0.0522 0.0522
Brugia malayi Protein kinase domain containing protein 0.0294 0.054 0.0776
Onchocerca volvulus 0.0182 0.0196 0.0114
Loa Loa (eye worm) STE/STE20/SLK protein kinase 0.0226 0.0332 0.0477
Echinococcus multilocularis casein kinase ii subunit alpha 0.0137 0.0056 0.0056
Loa Loa (eye worm) CMGC/SRPK protein kinase 0.0121 0.0005 0.0007
Echinococcus multilocularis casein kinase I delta 0.0258 0.0429 0.0429
Schistosoma mansoni protein kinase 0.1258 0.3525 0.7561
Loa Loa (eye worm) hypothetical protein 0.0667 0.1696 0.2436
Echinococcus multilocularis mitogen activated protein kinase 11 0.1203 0.3354 0.3354
Echinococcus granulosus raf serine:threonine protein kinase 0.0189 0.0215 0.0298
Loa Loa (eye worm) TK protein kinase 0.0343 0.0692 0.0994
Giardia lamblia Kinase, CMGC CDK 0.024 0.0375 0.3257
Trypanosoma cruzi casein kinase, putative 0.0258 0.0429 0.1268
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.042 0.0931 0.1338
Trichomonas vaginalis AGC family protein kinase 0.0294 0.054 0.4733
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0171 0.0161 0.0222
Entamoeba histolytica protein kinase, putative 0.0413 0.0909 0.7452
Loa Loa (eye worm) hypothetical protein 0.0618 0.1544 0.2219
Trypanosoma cruzi polo-like protein kinase, putative 0.021 0.028 0.0823
Echinococcus multilocularis tyrosine protein kinase HCK 0.0343 0.0692 0.0692
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0193 0.0227 0.0326
Entamoeba histolytica protein kinase, putative 0.0274 0.048 0.3937
Schistosoma mansoni protein kinase 0.043 0.0961 0.2061
Schistosoma mansoni neuroglian 0.0127 0.0023 0.0049
Loa Loa (eye worm) hypothetical protein 0.0119 0 0.0001
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0294 0.054 0.054
Echinococcus granulosus homeodomain interacting protein kinase 3 0.0236 0.0361 0.05
Brugia malayi ribosomal protein S6 kinase alpha 3 0.0404 0.088 0.1265
Echinococcus granulosus TGF-beta receptor type-1 0.0286 0.0516 0.0715
Loa Loa (eye worm) protein kinase domain-containing protein 0.0246 0.0392 0.0564
Schistosoma mansoni vesicular amine transporter 0.0252 0.0412 0.0884
Schistosoma mansoni serine/threonine protein kinase 0.0323 0.0632 0.1355
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0255 0.0419 0.0602
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0309 0.0586 0.1736
Schistosoma mansoni protein kinase 0.015 0.0096 0.0206
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0416 0.092 0.1322
Echinococcus granulosus tyrosine protein kinase HCK 0.0343 0.0692 0.0958
Giardia lamblia Kinase, CMGC GSK 0.0449 0.1022 0.8947
Loa Loa (eye worm) TKL/LRRK protein kinase 0.0189 0.0217 0.0312
Loa Loa (eye worm) hypothetical protein 0.0253 0.0416 0.0597
Trichomonas vaginalis AGC family protein kinase 0.0433 0.0972 0.8511
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0373 0.0785 0.1128
Schistosoma mansoni serine/threonine protein kinase 0.0121 0.0007 0.0014
Trichomonas vaginalis CAMK family protein kinase 0.021 0.028 0.2456
Plasmodium vivax casein kinase 1, putative 0.0258 0.0429 0.3735
Trypanosoma brucei polo-like protein kinase 0.021 0.028 0.0823
Loa Loa (eye worm) CAMK/PHK protein kinase 0.0199 0.0246 0.0354
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0121 0.0007 0.0017
Entamoeba histolytica PH domain containing protein kinase, putative 0.0212 0.0287 0.2352
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0392 0.0845 0.1214
Brugia malayi Protein kinase domain containing protein 0.0225 0.0329 0.0472
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.024 0.0375 0.1105
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0183 0.0198 0.0578
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0488 0.1142 0.3393
Echinococcus granulosus maternal embryonic leucine zipper kinase 0.0152 0.01 0.0139
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0513 0.1219 0.3626
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0309 0.0586 0.0812
Echinococcus granulosus tyrosine protein kinase Src42A 0.0353 0.0724 0.1003
Trichomonas vaginalis STE family protein kinase 0.0171 0.0161 0.1408
Trichomonas vaginalis CK1 family protein kinase 0.0258 0.0429 0.3762
Entamoeba histolytica hypothetical protein 0.0366 0.0763 0.6257
Brugia malayi Dual specificity mitogen-activated protein kinase kinase mek-2 0.0367 0.0768 0.1103
Brugia malayi Homeodomain interacting protein kinase protein 1 0.0236 0.0361 0.0519
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0309 0.0586 0.0586
Giardia lamblia Kinase, CAMK CAMKL 0.0187 0.0211 0.1814
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.1203 0.3354 1
Echinococcus granulosus cyclin dependent kinase 5 0.024 0.0375 0.0519
Echinococcus granulosus casein kinase I gamma 0.0246 0.0392 0.0543
Echinococcus multilocularis mitogen activated protein kinase 3 0.0121 0.0007 0.0007
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.02 0.025 0.0537
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0193 0.0227 0.0487
Loa Loa (eye worm) TK/FER protein kinase 0.0225 0.0329 0.0472
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0449 0.1022 0.1022
Brugia malayi Variant SH3 domain containing protein 0.02 0.025 0.036
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0187 0.0211 0.1814
Echinococcus multilocularis dual specificity protein kinase clk2 0.0488 0.1142 0.1142
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0309 0.0586 0.5115
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0183 0.0198 0.0578
Loa Loa (eye worm) hypothetical protein 0.0119 0 0.0001
Echinococcus granulosus casein kinase I delta 0.0258 0.0429 0.0595
Brugia malayi serine/threonine-protein kinase plk-2 0.021 0.028 0.0403
Trichomonas vaginalis CAMK family protein kinase 0.0172 0.0162 0.1423
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0236 0.0362 0.052
Brugia malayi ephrin receptor 1 precursor 0.014 0.0064 0.0092
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0618 0.1544 0.2219
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0293 0.0537 0.4408
Brugia malayi p70 ribosomal S6 kinase beta 0.0413 0.0909 0.1306
Leishmania major protein kinase A catalytic subunit isoform 1 0.0309 0.0586 0.1736
Schistosoma mansoni hypothetical protein 0.013 0.0034 0.0072
Brugia malayi Protein kinase domain containing protein 0.0189 0.0217 0.0312
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.1109 0.3064 0.3064
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0127 0.0023 0.0023
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0424 0.0943 0.2802
Loa Loa (eye worm) thyroid receptor interactor 0.0447 0.1015 0.1458
Schistosoma mansoni tyrosine kinase 0.0383 0.0818 0.1755
Leishmania major protein kinase, putative 0.0293 0.0537 0.159
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0455 0.1039 0.1492
Trichomonas vaginalis CAMK family protein kinase 0.021 0.028 0.2456
Brugia malayi Tyrosine-protein kinase abl-1 0.0381 0.081 0.1164
Echinococcus multilocularis dual specificity 0.0513 0.1219 0.1219
Echinococcus multilocularis epidermal growth factor receptor 0.0494 0.1161 0.1161
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0273 0.0476 0.0684
Trichomonas vaginalis CAMK family protein kinase 0.0172 0.0162 0.1423
Brugia malayi Protein kinase domain containing protein 0.0193 0.0229 0.0329
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0311 0.0593 0.1273
Brugia malayi Immunoglobulin I-set domain containing protein 0.0265 0.0452 0.065
Echinococcus granulosus tyrosine protein kinase Fyn 0.0543 0.1311 0.1815
Schistosoma mansoni serine/threonine protein kinase 0.0203 0.0258 0.0554
Schistosoma mansoni rap gtpase-activating protein 0.031 0.059 0.1265
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.0947 0.2563 0.3683
Echinococcus multilocularis casein kinase I alpha 0.0258 0.0429 0.0429
Onchocerca volvulus 0.0225 0.0329 0.0308
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0121 0.0007 0.0006
Brugia malayi bone morphogenetic protein type 1 receptor 0.0324 0.0635 0.0912
Brugia malayi casein kinase I 0.0258 0.0429 0.0617
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0252 0.0412 0.0884
Loa Loa (eye worm) variant SH3 domain-containing protein 0.02 0.025 0.036
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.0172 0.0162 0.047
Giardia lamblia Kinase, CMGC CDK 0.024 0.0375 0.3257
Echinococcus granulosus tyrosine protein kinase shark 0.0431 0.0965 0.1336
Echinococcus granulosus protein tyrosine kinase 0.1625 0.4662 0.6455
Schistosoma mansoni serine/threonine protein kinase 0.017 0.0158 0.0339
Loa Loa (eye worm) TK protein kinase 0.0457 0.1047 0.1504
Echinococcus multilocularis roundabout 2 0.0379 0.0804 0.0804
Echinococcus multilocularis activin receptor type 0.1273 0.3574 0.3574
Loa Loa (eye worm) CAMK protein kinase 0.0157 0.0118 0.0169
Schistosoma mansoni serine/threonine protein kinase 0.0274 0.0479 0.1027
Trichomonas vaginalis CMGC family protein kinase 0.0121 0.0007 0.0059
Brugia malayi Temporarily assigned gene name protein 59 0.031 0.059 0.0848
Loa Loa (eye worm) AUR protein kinase 0.0293 0.0537 0.0772
Schistosoma mansoni serine/threonine protein kinase 0.0309 0.0586 0.1258
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0543 0.1311 0.1311
Echinococcus granulosus expressed protein 0.0121 0.0005 0.0007
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0494 0.1161 0.1608
Loa Loa (eye worm) TK/FER protein kinase 0.0225 0.0329 0.0472
Trichomonas vaginalis CAMK family protein kinase 0.0172 0.0162 0.1423
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0182 0.0196 0.0271
Entamoeba histolytica protein kinase, putative 0.0175 0.0171 0.1405
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0172 0.0162 0.047
Schistosoma mansoni hypothetical protein 0.031 0.059 0.1265
Schistosoma mansoni serine/threonine protein kinase 0.0172 0.0162 0.0348
Echinococcus granulosus defective proboscis extension response 0.0252 0.0412 0.0571
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.082 0.217 0.3118
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0725 0.1876 0.1876
Brugia malayi protein C17H12.11 0.0182 0.0195 0.028
Trichomonas vaginalis CAMK family protein kinase 0.0172 0.0162 0.1423
Brugia malayi Serine/threonine-protein kinase Pim-3 0.1022 0.2796 0.4017
Schistosoma mansoni serine/threonine protein kinase 0.073 0.1891 0.4056
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.0472 0.1093 0.1571
Onchocerca volvulus 0.0397 0.0861 0.1087
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0171 0.0161 0.0222
Schistosoma mansoni serine/threonine protein kinase 0.0309 0.0586 0.1258
Trypanosoma cruzi cdc2-related kinase 1 0.024 0.0375 0.1105
Trypanosoma brucei STE20-like serine/threonine-protein kinase 1, putative 0.0122 0.0009 0.0014
Loa Loa (eye worm) hypothetical protein 0.0169 0.0156 0.0224
Trichomonas vaginalis STE family protein kinase 0.015 0.0096 0.0842
Brugia malayi Variant SH3 domain containing protein 0.02 0.025 0.036
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0121 0.0007 0.0006
Brugia malayi Immunoglobulin I-set domain containing protein 0.0127 0.0023 0.0033
Trichomonas vaginalis CMGC family protein kinase 0.0121 0.0007 0.0059
Echinococcus multilocularis 0.043 0.0961 0.0961
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0464 0.1069 0.1536
Loa Loa (eye worm) hypothetical protein 0.0703 0.1807 0.2597
Giardia lamblia Kinase, CMGC CK2 0.0137 0.0056 0.0446
Echinococcus multilocularis mitogen activated protein kinase 0.0121 0.0007 0.0007
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0488 0.1142 0.164
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.104 0.285 0.285
Brugia malayi cyclin-dependent kinase 7 homolog 0.0243 0.0384 0.0551
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0449 0.1022 0.1468
Brugia malayi Protein kinase domain containing protein 0.0225 0.0329 0.0472
Trichomonas vaginalis CMGC family protein kinase 0.0121 0.0007 0.0059
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0273 0.0476 0.0684
Brugia malayi Immunoglobulin I-set domain containing protein 0.0127 0.0023 0.0033
Echinococcus granulosus titin 0.0157 0.0118 0.0163
Loa Loa (eye worm) hypothetical protein 0.0406 0.0889 0.1278
Trypanosoma brucei Casein kinase II 0.0137 0.0056 0.0151
Entamoeba histolytica serine/threonine protein kinase, putative 0.0172 0.0162 0.1332
Schistosoma mansoni serine/threonine protein kinase 0.1224 0.3422 0.734
Echinococcus granulosus epidermal growth factor receptor 0.0494 0.1161 0.1608
Brugia malayi Muscleblind-like protein 0.0119 0 0.0001
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0127 0.0023 0.0031
Brugia malayi serine/threonine kinase 12 0.0293 0.0537 0.0772
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0457 0.1047 0.1047
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0191 0.0224 0.1927
Echinococcus granulosus neuroglian 0.0324 0.0634 0.0878
Echinococcus granulosus casein kinase ii subunit alpha 0.0137 0.0056 0.0077
Echinococcus granulosus dual specificity 0.0175 0.0171 0.0237
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0449 0.1022 0.3036
Echinococcus granulosus epidermal growth factor receptor 0.0628 0.1575 0.218
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0171 0.0161 0.0161
Entamoeba histolytica protein kinase, putative 0.015 0.0096 0.0788
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0121 0.0007 0.0006
Schistosoma mansoni ephrin receptor 0.0124 0.0014 0.003
Loa Loa (eye worm) G protein-coupled receptor kinase 1 0.0416 0.092 0.1322
Loa Loa (eye worm) hypothetical protein 0.0494 0.1159 0.1666
Echinococcus granulosus calcium activated potassium channel 0.0203 0.0258 0.0358
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.031 0.059 0.059
Trichomonas vaginalis CMGC family protein kinase 0.0488 0.1142 1
Echinococcus multilocularis PAK box P21 Rho binding 0.015 0.0096 0.0096
Echinococcus granulosus serine:threonine protein kinase 3 0.0288 0.0522 0.0723
Trichomonas vaginalis STE family protein kinase 0.0367 0.0768 0.6726
Loa Loa (eye worm) hypothetical protein 0.013 0.0034 0.0048
Echinococcus multilocularis roundabout 2 0.0127 0.0023 0.0023
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.042 0.0931 0.0931
Echinococcus granulosus tyrosine protein kinase Fyn 0.0543 0.1311 0.1815
Loa Loa (eye worm) hypothetical protein 0.0265 0.0452 0.065
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.1022 0.2796 0.387
Echinococcus granulosus casein kinase I delta 0.0258 0.0429 0.0595
Echinococcus granulosus activin receptor type 0.1273 0.3574 0.4948
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0273 0.0476 0.4148
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0449 0.1022 0.1468
Trypanosoma brucei protein kinase, putative 0.0449 0.1022 0.3036
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.024 0.0375 0.1105
Trichomonas vaginalis CMGC family protein kinase 0.0137 0.0056 0.0486
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0507 0.12 0.1662
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.024 0.0375 0.0539
Entamoeba histolytica p21-activated kinase 0.0191 0.0224 0.1834
Echinococcus multilocularis titin 0.0157 0.0118 0.0118
Loa Loa (eye worm) hypothetical protein 0.0366 0.0764 0.1098
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0258 0.0429 0.0617
Entamoeba histolytica casein kinase 1, putative 0.0258 0.0429 0.3522
Echinococcus granulosus NDR protein kinase 0.0294 0.054 0.0748
Leishmania major protein kinase, putative 0.0122 0.0009 0.0014
Trichomonas vaginalis AGC family protein kinase 0.0294 0.054 0.4733
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0625 0.1565 0.2167
Echinococcus granulosus contactin 0.0127 0.0023 0.0031
Loa Loa (eye worm) hypothetical protein 0.0169 0.0156 0.0224
Entamoeba histolytica protein kinase domain containing protein 0.0132 0.004 0.0324
Leishmania major protein kinase, putative 0.0488 0.1142 0.3393
Trichomonas vaginalis AGC family protein kinase 0.0309 0.0586 0.5136
Schistosoma mansoni protein kinase C mu 0.047 0.1086 0.2329
Schistosoma mansoni serine/threonine protein kinase 0.0157 0.0118 0.0253
Echinococcus multilocularis cyclin dependent kinase 7 0.0227 0.0335 0.0335
Onchocerca volvulus 0.0409 0.0898 0.114
Echinococcus granulosus casein kinase i 0.0258 0.0429 0.0595
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0236 0.0362 0.0362
Echinococcus granulosus dual specificity 0.0513 0.1219 0.1688
Brugia malayi Immunoglobulin I-set domain containing protein 0.0127 0.0023 0.0033
Loa Loa (eye worm) TK/EPH protein kinase 0.0189 0.0217 0.0312
Schistosoma mansoni protein kinase 0.0739 0.192 0.4118
Echinococcus granulosus protein kinase shaggy 0.0449 0.1022 0.1415
Echinococcus granulosus Protein kinase C brain isozyme 0.0411 0.0903 0.1251
Schistosoma mansoni serine/threonine protein kinase 0.0236 0.0361 0.0774
Brugia malayi protein kinase C II. 0.0373 0.0785 0.1128
Echinococcus granulosus serine:threonine protein kinase N2 0.0939 0.254 0.3516
Loa Loa (eye worm) hypothetical protein 0.0193 0.0229 0.0329
Brugia malayi Protein kinase domain containing protein 0.024 0.0375 0.0539
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0273 0.0476 0.1407
Schistosoma mansoni tyrosine kinase 0.0543 0.1311 0.2812
Onchocerca volvulus 0.0225 0.0329 0.0308
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0193 0.0227 0.0314
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0273 0.0476 0.0659
Schistosoma mansoni tyrosine kinase 0.0727 0.1883 0.404
Echinococcus granulosus muscleblind protein 0.0119 0 0.0001
Echinococcus multilocularis homeodomain interacting protein kinase 3 0.0236 0.0361 0.0361
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0309 0.0586 0.1736
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0273 0.0476 0.4148
Loa Loa (eye worm) hypothetical protein 0.0301 0.0562 0.0808
Loa Loa (eye worm) TK/FAK protein kinase 0.1643 0.4718 0.678
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0416 0.092 0.1322
Trichomonas vaginalis CMGC family protein kinase 0.0137 0.0056 0.0486
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.1203 0.3354 1
Loa Loa (eye worm) CAMK/PKD protein kinase 0.047 0.1086 0.156
Onchocerca volvulus 0.1092 0.3012 0.423
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0513 0.1219 0.1752
Echinococcus granulosus serine:threonine protein kinase mig 15 0.0667 0.1696 0.2347
Loa Loa (eye worm) CAMK/PIM protein kinase 0.1022 0.2796 0.4017
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0725 0.1876 0.2597
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0517 0.1232 0.1232
Trichomonas vaginalis AGC family protein kinase 0.0172 0.0163 0.1426
Loa Loa (eye worm) AGC/PKG protein kinase 0.017 0.0158 0.0227
Brugia malayi protein-tyrosine kinase 0.0457 0.1047 0.1504
Schistosoma mansoni protein kinase 0.0171 0.0161 0.0345
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.1022 0.2796 0.3914
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0273 0.0476 0.0684
Plasmodium falciparum NIMA related kinase 1 0.0172 0.0163 0.139
Schistosoma mansoni tyrosine kinase 0.0383 0.0818 0.1755
Loa Loa (eye worm) hypothetical protein 0.044 0.0995 0.1429
Echinococcus granulosus tyrosine protein kinase Src42A 0.0543 0.1311 0.1815
Schistosoma mansoni cell adhesion molecule 0.0127 0.0023 0.0049
Schistosoma mansoni tyrosine kinase 0.0383 0.0818 0.1755
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0596 0.1477 0.2045
Echinococcus granulosus tyrosine protein kinase Blk 0.0457 0.1047 0.1449
Brugia malayi hypothetical protein 0.1387 0.3925 0.564
Echinococcus granulosus leucine rich repeat serine:threonine protein 0.0189 0.0217 0.03
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0294 0.054 0.0748
Schistosoma mansoni protein kinase 0.1258 0.3525 0.7561
Trichomonas vaginalis CAMK family protein kinase 0.0152 0.01 0.0877
Loa Loa (eye worm) hypothetical protein 0.0444 0.1005 0.1445
Schistosoma mansoni serine/threonine kinase 0.0297 0.0552 0.1183
Echinococcus multilocularis raf serine:threonine protein kinase 0.0189 0.0215 0.0215
Entamoeba histolytica protein kinase domain containing protein 0.0293 0.0537 0.4408
Echinococcus granulosus casein kinase I alpha 0.0258 0.0429 0.0595
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.1203 0.3354 1
Schistosoma mansoni tyrosine kinase 0.0431 0.0965 0.2069
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0273 0.0476 0.0476
Entamoeba histolytica protein kinase, putative 0.0187 0.021 0.1725
Echinococcus granulosus STE20 serine:threonine protein kinase 0.0516 0.123 0.1703
Trypanosoma brucei aurora B kinase 0.0293 0.0537 0.159
Brugia malayi Protein kinase domain containing protein 0.0282 0.0503 0.0723
Trichomonas vaginalis CMGC family protein kinase 0.0137 0.0056 0.0486
Loa Loa (eye worm) hypothetical protein 0.0168 0.0151 0.0216
Giardia lamblia Kinase, CMGC DYRK 0.0175 0.0171 0.1464
Echinococcus multilocularis STE20 serine:threonine protein kinase 0.0516 0.123 0.123
Schistosoma mansoni tyrosine kinase 0.0188 0.0214 0.046
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0172 0.0162 0.047
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.1258 0.3525 0.4881
Trichomonas vaginalis CAMK family protein kinase 0.021 0.028 0.2456
Schistosoma mansoni serine/threonine protein kinase 0.0293 0.0537 0.1153
Echinococcus multilocularis neuroglian 0.0127 0.0023 0.0023
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0449 0.1022 0.1415
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0309 0.0586 0.1736
Echinococcus granulosus roundabout 2 0.0127 0.0023 0.0031
Trichomonas vaginalis STE family protein kinase 0.0171 0.0161 0.1408
Loa Loa (eye worm) AGC/PKN protein kinase 0.0939 0.254 0.3649
Schistosoma mansoni adapter molecule crk 0.02 0.025 0.0537
Trichomonas vaginalis CAMK family protein kinase 0.0172 0.0162 0.1423
Trypanosoma brucei protein kinase, putative 0.0183 0.0198 0.0578
Echinococcus granulosus c-Jun N-terminal kinases 0.1224 0.3422 0.4738
Loa Loa (eye worm) TK/INSR protein kinase 0.0712 0.1836 0.2638
Leishmania major protein kinase A catalytic subunit 0.0309 0.0586 0.1736
Echinococcus multilocularis cyclin dependent kinase 5 0.024 0.0375 0.0375
Echinococcus granulosus dual specificity 0.0175 0.0171 0.0237
Loa Loa (eye worm) hypothetical protein 0.0294 0.0542 0.0779
Giardia lamblia Kinase, CAMK CAMKL 0.0187 0.0211 0.1814
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.104 0.285 0.4096
Echinococcus multilocularis cyclin dependent kinase 1 0.024 0.0375 0.0375
Trichomonas vaginalis CMGC family protein kinase 0.0175 0.0171 0.15
Echinococcus multilocularis growth factor receptor bound protein 2 0.02 0.025 0.025
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.024 0.0375 0.3257
Toxoplasma gondii aurora kinase 0.0293 0.0537 0.4686
Brugia malayi Immunoglobulin I-set domain containing protein 0.0157 0.0118 0.0169
Trichomonas vaginalis AGC family protein kinase 0.0293 0.0537 0.4708
Entamoeba histolytica cell division protein kinase 2, putative 0.024 0.0375 0.3076
Echinococcus multilocularis protein kinase shaggy 0.0449 0.1022 0.1022
Echinococcus multilocularis maternal embryonic leucine zipper kinase 0.0152 0.01 0.01
Giardia lamblia Kinase, STE STE20 0.0367 0.0768 0.6712
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0273 0.0476 0.0659
Loa Loa (eye worm) TK/EGFR protein kinase 0.0628 0.1575 0.2263
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0309 0.0586 0.1736
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0273 0.0476 0.0659
Onchocerca volvulus 0.0449 0.1022 0.1321
Toxoplasma gondii CMGC kinase, CK2 family 0.0137 0.0056 0.0446
Schistosoma mansoni serine/threonine protein kinase 0.0162 0.0133 0.0285
Schistosoma mansoni serine/threonine protein kinase 0.0488 0.1142 0.2448
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0121 0.0007 0.0006
Loa Loa (eye worm) hypothetical protein 0.0273 0.0476 0.0684
Echinococcus multilocularis roundabout 2 0.0127 0.0023 0.0023
Trichomonas vaginalis CMGC family protein kinase 0.0175 0.0171 0.15
Loa Loa (eye worm) hypothetical protein 0.0281 0.05 0.0718
Echinococcus multilocularis mitogen activated protein kinase 14 0.1203 0.3354 0.3354
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0543 0.1311 0.1815
Schistosoma mansoni serine/threonine protein kinase 0.0373 0.0785 0.1684
Brugia malayi Protein kinase domain containing protein 0.0618 0.1544 0.2219
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.031 0.059 0.1747
Giardia lamblia Kinase, CMGC CLK 0.0488 0.1142 1
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0309 0.0586 0.5115
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0309 0.0586 0.0812
Echinococcus multilocularis serine:threonine protein kinase N2 0.0939 0.254 0.254
Echinococcus granulosus dual specificity protein kinase clk2 0.0488 0.1142 0.158
Schistosoma mansoni tyrosine kinase 0.0494 0.1161 0.249
Echinococcus granulosus mitogen activated protein kinase 3 0.0121 0.0007 0.0009
Brugia malayi hypothetical protein 0.031 0.059 0.0848
Trichomonas vaginalis CMGC family protein kinase 0.0137 0.0056 0.0486
Brugia malayi probable protein kinase 0.0739 0.192 0.2759
Trichomonas vaginalis CAMK family protein kinase 0.0193 0.0229 0.2007
Brugia malayi Immunoglobulin I-set domain containing protein 0.1497 0.4265 0.6129
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0122 0.0009 0.0014
Brugia malayi Doublecortin family protein 0.0186 0.0207 0.0297
Echinococcus multilocularis transfer RNA-Thr 0.0604 0.1502 0.1502
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0193 0.0227 0.0487
Brugia malayi Casein kinase II, alpha chain 0.0137 0.0056 0.008
Plasmodium falciparum casein kinase 2, alpha subunit 0.0137 0.0056 0.0446
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0225 0.0329 0.2696
Schistosoma mansoni serine/threonine protein kinase 0.0203 0.0258 0.0554
Echinococcus multilocularis Immunoglobulin 0.0252 0.0412 0.0412
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.031 0.059 0.1747
Plasmodium falciparum protein kinase, putative 0.0183 0.0198 0.1704
Echinococcus granulosus MAM 0.0169 0.0156 0.0216
Echinococcus granulosus cGMP dependent protein kinase 1 0.017 0.0158 0.0219
Brugia malayi C1-like domain containing protein 0.047 0.1086 0.156
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0309 0.0586 0.0842
Toxoplasma gondii casein kinase I 0.0258 0.0429 0.3735
Echinococcus granulosus calcium dependent protein kinase 0.02 0.0252 0.0348
Brugia malayi Protein kinase domain containing protein 0.0712 0.1836 0.2638
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0172 0.0163 0.139
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.021 0.028 0.028
Loa Loa (eye worm) hypothetical protein 0.0319 0.062 0.0891
Leishmania major protein kinase A catalytic subunit isoform 2 0.0309 0.0586 0.1736
Brugia malayi Immunoglobulin I-set domain containing protein 0.0172 0.0163 0.0235
Loa Loa (eye worm) TK/FER protein kinase 0.0225 0.0329 0.0472
Loa Loa (eye worm) hypothetical protein 0.031 0.059 0.0848
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0411 0.0903 0.0903
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0309 0.0586 0.1736
Brugia malayi Protein kinase domain containing protein 0.0433 0.0972 0.1396
Schistosoma mansoni nck2/grb4 0.02 0.025 0.0537
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0543 0.1311 0.1815
Trichomonas vaginalis CMGC family protein kinase 0.0449 0.1022 0.8951
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0309 0.0586 0.5115
Trichomonas vaginalis CAMK family protein kinase 0.0172 0.0162 0.1423
Trypanosoma cruzi Protein kinase B 0.0212 0.0287 0.0842
Echinococcus multilocularis ephrin type A receptor 4 A 0.0172 0.0165 0.0165
Schistosoma mansoni serine/threonine protein kinase 0.0234 0.0355 0.0762
Echinococcus multilocularis Immunoglobulin 0.0252 0.0412 0.0412
Trichomonas vaginalis STE family protein kinase 0.0367 0.0768 0.6726
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.2452 0.7223 1
Schistosoma mansoni serine/threonine protein kinase 0.0456 0.1042 0.2235
Trichomonas vaginalis STE family protein kinase 0.0171 0.0161 0.1408
Loa Loa (eye worm) hypothetical protein 0.0169 0.0156 0.0224
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0456 0.1042 0.1498
Echinococcus granulosus cyclin dependent kinase 9 0.0162 0.0133 0.0184
Loa Loa (eye worm) CMGC/CDK/CDK9 protein kinase 0.0162 0.0133 0.0191
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0183 0.0198 0.0275
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.1258 0.3525 0.3525
Plasmodium falciparum calcium-dependent protein kinase 3 0.0273 0.0476 0.4148
Schistosoma mansoni serine/threonine-protein kinase 0.0212 0.0287 0.0615
Plasmodium falciparum protein kinase 5 0.024 0.0375 0.3257
Schistosoma mansoni serine/threonine protein kinase 0.0227 0.0335 0.0718
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0543 0.1311 0.1311
Brugia malayi Furin-like cysteine rich region family protein 0.0628 0.1575 0.2263
Onchocerca volvulus 0.0225 0.0329 0.0308
Echinococcus multilocularis mitogen activated protein kinase 11 0.1203 0.3354 0.3354
Echinococcus granulosus tyrosine protein kinase ABL1 0.0842 0.2238 0.3099
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.0985 0.268 0.3851
Giardia lamblia Kinase, STE STE20 0.0122 0.0009 0.0041
Trichomonas vaginalis CAMK family protein kinase 0.021 0.028 0.2456
Trichomonas vaginalis AGC family protein kinase 0.0433 0.0972 0.8511
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0172 0.0163 0.139
Schistosoma mansoni serine/threonine protein kinase 0.0939 0.254 0.5447
Schistosoma mansoni serine/threonine protein kinase 0.0411 0.0903 0.1938
Loa Loa (eye worm) hypothetical protein 0.0347 0.0704 0.1012
Trypanosoma brucei protein kinase, putative 0.0137 0.0055 0.0151
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.043 0.0961 0.1381
Schistosoma mansoni nephrin 0.0337 0.0674 0.1447
Trichomonas vaginalis AGC family protein kinase 0.0433 0.0972 0.8511
Trypanosoma cruzi casein kinase, putative 0.0258 0.0429 0.1268
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0191 0.0224 0.0654
Trichomonas vaginalis CK1 family protein kinase 0.0258 0.0429 0.3762
Loa Loa (eye worm) hypothetical protein 0.031 0.059 0.0848
Leishmania major protein kinase, putative 0.0183 0.0198 0.0578
Plasmodium falciparum cGMP-dependent protein kinase 0.017 0.0158 0.1349
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0136 0.0052 0.0075
Trichomonas vaginalis CMGC family protein kinase 0.0175 0.0171 0.15
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0625 0.1565 0.1565
Echinococcus multilocularis c Jun NH2 terminal kinase 0.1224 0.3422 0.3422
Loa Loa (eye worm) TK/KIN16 protein kinase 0.1497 0.4265 0.6129
Plasmodium falciparum serine/threonine protein kinase, putative 0.0293 0.0537 0.4686
Brugia malayi SRC-1 0.0543 0.1311 0.1884
Brugia malayi Protein kinase domain containing protein 0.0593 0.1466 0.2106
Echinococcus multilocularis rac serine:threonine kinase 0.0212 0.0287 0.0287
Echinococcus multilocularis tyrosine protein kinase Blk 0.0457 0.1047 0.1047
Schistosoma mansoni serine/threonine protein kinase 0.0309 0.0586 0.1258
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.021 0.028 0.0823
Trichomonas vaginalis AGC family protein kinase 0.0433 0.0972 0.8511
Trichomonas vaginalis CMGC family protein kinase 0.0137 0.0056 0.0486
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0456 0.1042 0.1042
Leishmania major casein kinase II, putative 0.0137 0.0056 0.0151
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0513 0.1219 0.3626
Loa Loa (eye worm) TK protein kinase 0.0668 0.1699 0.2442
Trypanosoma cruzi casein kinase II, putative 0.0137 0.0056 0.0151
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0513 0.1219 0.3626
Trypanosoma cruzi cdc2-related kinase 1 0.024 0.0375 0.1105
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0309 0.0586 0.1736
Brugia malayi Protein kinase domain containing protein 0.1643 0.4718 0.678
Brugia malayi protein kinase C3,putative 0.023 0.0344 0.0494
Schistosoma mansoni serine/threonine protein kinase 0.0455 0.1039 0.2228
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0449 0.1022 0.2192
Loa Loa (eye worm) hypothetical protein 0.0366 0.0764 0.1098
Brugia malayi Protein kinase domain containing protein 0.0225 0.0329 0.0472
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.018 0.0189 0.0261
Schistosoma mansoni protein kinase 0.0367 0.0768 0.1647
Trichomonas vaginalis CAMK family protein kinase 0.0172 0.0162 0.1423
Schistosoma mansoni serine/threonine protein kinase 0.0294 0.054 0.1159
Entamoeba histolytica casein kinase, putative 0.0258 0.0429 0.3522
Trichomonas vaginalis CMGC family protein kinase 0.024 0.0375 0.3286
Plasmodium falciparum casein kinase 1 0.0258 0.0429 0.3735
Toxoplasma gondii AGC kinase 0.0309 0.0586 0.5115
Brugia malayi Stress-activated protein kinase jnk-1 0.1224 0.3422 0.4917
Schistosoma mansoni ste20-related kinase 0.0238 0.0368 0.079
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.0742 0.1929 0.2671
Entamoeba histolytica PH domain containing protein kinase, putative 0.0329 0.0649 0.5324
Echinococcus granulosus hypothetical protein 0.0415 0.0917 0.1269
Trypanosoma cruzi cdc2-related kinase 3 0.024 0.0375 0.1105
Brugia malayi Protein kinase domain containing protein 0.0947 0.2563 0.3683
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.0282 0.0503 0.0723
Onchocerca volvulus Serine\/threonine kinase homolog 0.021 0.028 0.0238
Trichomonas vaginalis AGC family protein kinase 0.0314 0.0603 0.5284
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0507 0.12 0.12
Brugia malayi intracellular kinase 0.0449 0.1022 0.1468
Echinococcus granulosus roundabout 2 0.0127 0.0023 0.0031
Brugia malayi putative serine/threonine kinase SADA gamma 0.0172 0.0162 0.0233
Plasmodium vivax calcium-dependent protein kinase, putative 0.0273 0.0476 0.4148
Toxoplasma gondii AGC kinase 0.0413 0.0909 0.7951
Loa Loa (eye worm) hypothetical protein 0.0319 0.062 0.0891
Schistosoma mansoni serine/threonine protein kinase 0.0121 0.0005 0.001
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0172 0.0162 0.0162
Trypanosoma brucei rac serine-threonine kinase, putative 0.0433 0.0972 0.2886
Trypanosoma cruzi aurora B kinase, putative 0.0293 0.0537 0.159
Schistosoma mansoni hypothetical protein 0.0169 0.0156 0.0334
Trypanosoma cruzi casein kinase, putative 0.0258 0.0429 0.1268
Entamoeba histolytica protein kinase, putative 0.0513 0.1219 1
Schistosoma mansoni hypothetical protein 0.0169 0.0156 0.0334
Schistosoma mansoni serine/threonine protein kinase 0.0273 0.0476 0.1022
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.1203 0.3354 1
Echinococcus granulosus phosphorylase kinase gamma subunit 0.0199 0.0246 0.0341
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0172 0.0163 0.0235
Giardia lamblia Aurora kinase 0.0293 0.0537 0.4686
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0175 0.0171 0.0497
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0449 0.1022 0.8947
Echinococcus multilocularis G protein coupled receptor kinase 6 0.0416 0.092 0.092
Brugia malayi Protein kinase domain containing protein 0.0604 0.1502 0.2159
Loa Loa (eye worm) AUR protein kinase 0.0293 0.0537 0.0772
Echinococcus multilocularis 0.0157 0.0116 0.0116
Brugia malayi SH2 domain containing protein 0.0517 0.1232 0.1771
Brugia malayi casein kinase 1, delta 0.0258 0.0429 0.0617
Brugia malayi Protein kinase c protein 2 0.019 0.0219 0.0314
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0183 0.0198 0.0198
Echinococcus multilocularis dual specificity 0.0175 0.0171 0.0171
Trichomonas vaginalis AGC family protein kinase 0.0309 0.0589 0.5159
Echinococcus granulosus NCK adaptor protein 0.02 0.025 0.0347
Loa Loa (eye worm) IKK protein kinase 0.2367 0.6959 1
Trichomonas vaginalis CMGC family protein kinase 0.0175 0.0171 0.15
Echinococcus granulosus dual specificity 0.0175 0.0171 0.0237
Echinococcus granulosus neuroglian 0.0127 0.0023 0.0031
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0182 0.0196 0.0196
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.031 0.059 0.0817
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0625 0.1565 0.2249
Loa Loa (eye worm) hypothetical protein 0.0409 0.0898 0.129
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0127 0.0023 0.0023
Brugia malayi Protein kinase domain containing protein 0.0225 0.0329 0.0472
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0127 0.0023 0.0023
Echinococcus multilocularis cyclin dependent kinase 0.024 0.0375 0.0375
Entamoeba histolytica protein kinase, putative 0.0294 0.054 0.4431
Trichomonas vaginalis CAMK family protein kinase 0.0172 0.0162 0.1423
Loa Loa (eye worm) TK/ROR protein kinase 0.0182 0.0196 0.0282
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0543 0.1311 0.1311
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0488 0.1142 0.3393
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0121 0.0007 0.001
Echinococcus granulosus protein kinase c iota type 0.0451 0.1028 0.1424
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.024 0.0375 0.0519
Echinococcus multilocularis TGF beta receptor type 1 0.0286 0.0516 0.0516
Loa Loa (eye worm) TK/FER protein kinase 0.0225 0.0329 0.0472
Loa Loa (eye worm) AUR protein kinase 0.0293 0.0537 0.0772
Brugia malayi Protein kinase domain containing protein 0.0513 0.1219 0.1752
Trichomonas vaginalis CMGC family protein kinase 0.0137 0.0056 0.0486
Loa Loa (eye worm) hypothetical protein 0.0252 0.0412 0.0592
Echinococcus multilocularis calcium activated potassium channel 0.0203 0.0258 0.0258
Schistosoma mansoni serine/threonine protein kinase 0.0246 0.0392 0.0842
Loa Loa (eye worm) hypothetical protein 0.019 0.0219 0.0315
Trichomonas vaginalis AGC family protein kinase 0.0293 0.0537 0.4708
Loa Loa (eye worm) hypothetical protein 0.019 0.0219 0.0315
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0488 0.1142 0.3393
Echinococcus granulosus tyrosine protein kinase Btk29A 0.1109 0.3064 0.4243
Schistosoma mansoni protein kinase 0.0286 0.0516 0.1108
Brugia malayi hypothetical protein 0.0265 0.0452 0.065
Echinococcus multilocularis protein kinase c epsilon type 0.0373 0.0785 0.0785
Brugia malayi Immunoglobulin I-set domain containing protein 0.0668 0.1699 0.2442
Brugia malayi SH2 domain containing protein 0.0225 0.0329 0.0472
Echinococcus granulosus fibroblast growth factor receptor 4 0.0596 0.1477 0.2045
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0517 0.1232 0.1706
Schistosoma mansoni serine/threonine protein kinase 0.0323 0.0632 0.1355
Echinococcus multilocularis serine:threonine protein kinase N2 0.0646 0.163 0.163
Giardia lamblia Kinase, CK1 Casein kinase 0.0258 0.0429 0.3735
Echinococcus multilocularis N chimaerin 0.0193 0.0227 0.0227
Echinococcus granulosus rho-associated protein kinase 1 0.0354 0.0726 0.1005
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0294 0.0542 0.075
Trichomonas vaginalis CAMK family protein kinase 0.0172 0.0162 0.1423
Loa Loa (eye worm) AGC/PKA protein kinase 0.0309 0.0586 0.0842
Entamoeba histolytica protein kinase, putative 0.0293 0.0537 0.4408
Giardia lamblia Kinase, AGC PKA 0.0191 0.0224 0.1927
Schistosoma mansoni tyrosine kinase 0.0224 0.0326 0.0698
Trichomonas vaginalis CAMK family protein kinase 0.0172 0.0162 0.1423
Trichomonas vaginalis AGC family protein kinase 0.0293 0.0537 0.4708
Echinococcus granulosus TGF beta receptor type 1 0.0286 0.0516 0.0715
Echinococcus granulosus twitchin 0.0397 0.0859 0.1189
Onchocerca volvulus 0.0258 0.0429 0.0456
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0252 0.0412 0.0884
Echinococcus granulosus dual specificity mitogen activated protein 0.0367 0.0768 0.1063
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0293 0.0537 0.4408
Brugia malayi Protein kinase domain containing protein 0.0265 0.0451 0.0648
Echinococcus multilocularis MAM 0.0169 0.0156 0.0156
Entamoeba histolytica protein kinase 2, putative 0.0191 0.0224 0.1836
Onchocerca volvulus 0.0225 0.0329 0.0308
Trichomonas vaginalis CAMK family protein kinase 0.0172 0.0162 0.1423
Entamoeba histolytica protein kinase, putative 0.0343 0.0692 0.5673
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0172 0.0162 0.047
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0449 0.1022 0.3036
Schistosoma mansoni serine/threonine protein kinase 0.0507 0.12 0.2574
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0258 0.0429 0.1268
Echinococcus granulosus serine:threonine protein kinase TAO1 0.1387 0.3925 0.5434
Plasmodium vivax serine/threonine kinase-1, putative 0.0488 0.1142 1
Echinococcus granulosus Immunoglobulin 0.0252 0.0412 0.0571
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0236 0.0362 0.0501
Echinococcus multilocularis hypothetical protein 0.013 0.0034 0.0034
Echinococcus multilocularis casein kinase I gamma 0.0246 0.0392 0.0392
Echinococcus granulosus casein kinase I alpha 0.0258 0.0429 0.0595
Trypanosoma cruzi cdc2-related kinase 3 0.024 0.0375 0.1105
Schistosoma mansoni kinase 0.0272 0.0474 0.1018
Trichomonas vaginalis CAMK family protein kinase 0.0172 0.0162 0.1423
Loa Loa (eye worm) TK/FER protein kinase 0.0517 0.1232 0.1771
Schistosoma mansoni protein kinase 0.0183 0.0198 0.0426
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0171 0.0161 0.0222
Echinococcus multilocularis myosin iiia 0.0122 0.0009 0.0009
Schistosoma mansoni serine/threonine kinase 0.0294 0.054 0.1159
Plasmodium falciparum calcium-dependent protein kinase 1 0.0273 0.0476 0.4148
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0273 0.0476 0.4148
Echinococcus multilocularis cGMP dependent protein kinase 1 0.017 0.0158 0.0158
Trichomonas vaginalis CAMK family protein kinase 0.021 0.028 0.2456
Loa Loa (eye worm) TK protein kinase 0.0403 0.0878 0.1261
Trichomonas vaginalis AGC family protein kinase 0.0433 0.0972 0.8511
Entamoeba histolytica protein kinase, putative 0.0433 0.0972 0.7968
Entamoeba histolytica casein kinase, putative 0.0137 0.0056 0.0455
Brugia malayi MAP kinase sur-1 0.0121 0.0007 0.001
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0323 0.0632 0.0875
Echinococcus multilocularis serine:threonine protein kinase 38 0.0294 0.054 0.054
Loa Loa (eye worm) TK/FER protein kinase 0.0225 0.0329 0.0472
Echinococcus multilocularis NCK adaptor protein 0.0207 0.0271 0.0271
Loa Loa (eye worm) camk/dcamkl protein kinase 0.0186 0.0207 0.0297
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0137 0.0056 0.0446
Trichomonas vaginalis CAMK family protein kinase 0.0172 0.0162 0.1423
Giardia lamblia Kinase, NEK 0.0172 0.0163 0.139
Echinococcus granulosus cyclin dependent kinase 7 0.0227 0.0335 0.0464
Onchocerca volvulus 0.0169 0.0156 0.0056
Echinococcus granulosus aurora kinase A 0.0293 0.0537 0.0744
Trichomonas vaginalis CMGC family protein kinase 0.0175 0.0171 0.15
Schistosoma mansoni growth factor receptor-bound protein 0.0207 0.0271 0.0581
Brugia malayi serine/threonine protein kinase 6 0.0293 0.0537 0.0772
Echinococcus multilocularis tyrosine protein kinase Abl 0.0547 0.1323 0.1323
Echinococcus granulosus tyrosine protein kinase Src64B 0.0543 0.1311 0.1815
Brugia malayi Protein kinase domain containing protein 0.0199 0.0246 0.0354
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0137 0.0056 0.008
Loa Loa (eye worm) hypothetical protein 0.0265 0.0452 0.065
Echinococcus granulosus ephrin type A receptor 4 A 0.0172 0.0165 0.0228
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0513 0.1219 0.3626
Loa Loa (eye worm) gastrulation defective protein 1 0.052 0.1241 0.1784
Trichomonas vaginalis AGC family protein kinase 0.0433 0.0972 0.8511
Schistosoma mansoni serine/threonine protein kinase 0.0488 0.1142 0.2448
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0309 0.0586 0.0586
Echinococcus multilocularis twitchin 0.0144 0.0078 0.0078
Schistosoma mansoni tyrosine kinase 0.0316 0.061 0.1308
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0309 0.0586 0.1736
Brugia malayi STE20-like kinase MST 0.0288 0.0522 0.0751
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0175 0.0171 0.0497
Schistosoma mansoni serine/threonine protein kinase 0.0172 0.0162 0.0348
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0324 0.0635 0.0912
Trichomonas vaginalis STE family protein kinase 0.0367 0.0768 0.6726
Schistosoma mansoni titin 0.0157 0.0118 0.0253
Toxoplasma gondii AGC kinase 0.0309 0.0586 0.5115
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0618 0.1544 0.2219
Echinococcus multilocularis mitogen activated protein kinase 14 0.1203 0.3354 0.3354
Echinococcus multilocularis casein kinase i 0.0258 0.0429 0.0429
Schistosoma mansoni serine/threonine protein kinase 0.0593 0.1466 0.3144
Trichomonas vaginalis CMGC family protein kinase 0.0449 0.1022 0.8951
Echinococcus granulosus insulin receptor 0.0712 0.1836 0.2541
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0294 0.054 0.0748
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0185 0.0205 0.0597
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.0175 0.0171 0.0497
Echinococcus multilocularis rho associated protein kinase 0.0354 0.0726 0.0726

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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