Detailed information for compound 1052768

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 404.333 | Formula: C21H23Cl2N3O
  • H donors: 0 H acceptors: 1 LogP: 4.6 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: COCCN1CC[C@@H](C1)N(c1ccc(c(c1)Cl)C#N)Cc1ccccc1Cl
  • InChi: 1S/C21H23Cl2N3O/c1-27-11-10-25-9-8-19(15-25)26(14-17-4-2-3-5-20(17)22)18-7-6-16(13-24)21(23)12-18/h2-7,12,19H,8-11,14-15H2,1H3/t19-/m0/s1
  • InChiKey: HHPQPMZEABBAEF-IBGZPJMESA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens progesterone receptor Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) variant SH3 domain-containing protein 0.041 0.0181 0.0229
Brugia malayi Serine/threonine-protein kinase SULU 0.2911 0.2887 0.3722
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.063 0.0419 0.0617
Trichomonas vaginalis conserved hypothetical protein 0.0261 0.002 0.014
Brugia malayi Furin-like cysteine rich region family protein 0.107 0.0895 0.1151
Trypanosoma brucei casein kinase I, isoform 2 0.0648 0.0439 0.0647
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0335 0.0099 0.0099
Entamoeba histolytica protein kinase domain containing protein 0.0261 0.002 0.0145
Schistosoma mansoni serine/threonine protein kinase 0.0366 0.0133 0.0325
Loa Loa (eye worm) TK/FER protein kinase 0.0261 0.002 0.0021
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.1493 0.1352 0.1352
Brugia malayi Prion-like- 0.0298 0.006 0.0073
Trypanosoma cruzi casein kinase, putative 0.0648 0.0439 0.0647
Echinococcus granulosus kinase suppressor of Ras 1 0.0261 0.002 0.0024
Trichomonas vaginalis TKL family protein kinase 0.0261 0.002 0.014
Loa Loa (eye worm) hypothetical protein 0.0879 0.0689 0.0885
Entamoeba histolytica tyrosin kinase, putative 0.0261 0.002 0.0145
Echinococcus multilocularis dual specificity 0.13 0.1144 0.1144
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0261 0.002 0.0145
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0585 0.037 0.0545
Trichomonas vaginalis STE family protein kinase 0.0261 0.002 0.014
Loa Loa (eye worm) AGC/AKT protein kinase 0.0754 0.0553 0.071
Onchocerca volvulus 0.1221 0.1059 0.1344
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0352 0.0119 0.0149
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0284 0.0045 0.0391
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.1076 0.0902 0.0902
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0335 0.0099 0.0099
Brugia malayi protein C17H12.11 0.0637 0.0426 0.0546
Schistosoma mansoni tyrosine kinase 0.0859 0.0667 0.1662
Trichomonas vaginalis AGC family protein kinase 0.0754 0.0553 0.4666
Entamoeba histolytica hypothetical protein 0.0263 0.0022 0.0168
Trichomonas vaginalis TKL family protein kinase 0.0261 0.002 0.014
Loa Loa (eye worm) hypothetical protein 0.0964 0.0781 0.1003
Brugia malayi Tyrosine-protein kinase F09A5.2 in chromosome X, putative 0.0261 0.002 0.0021
Loa Loa (eye worm) TKL/RAF/KSR protein kinase 0.0261 0.002 0.0021
Schistosoma mansoni serine/threonine protein kinase 0.0313 0.0077 0.0184
Entamoeba histolytica protein kinase, putative 0.1221 0.1059 0.9255
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0651 0.0442 0.3846
Echinococcus granulosus phosphorylase kinase gamma subunit 0.0313 0.0077 0.0109
Plasmodium vivax calcium-dependent protein kinase, putative 0.0585 0.037 0.3478
Brugia malayi Immunoglobulin I-set domain containing protein 0.0703 0.0498 0.0638
Loa Loa (eye worm) hypothetical protein 0.0585 0.037 0.0474
Onchocerca volvulus Tyrosine kinase homolog 0.3149 0.3144 0.4041
Brugia malayi cell division control protein 2 homolog 0.0488 0.0266 0.0339
Schistosoma mansoni tyrosine kinase 0.0662 0.0454 0.1129
Brugia malayi Protein kinase domain containing protein 0.0576 0.0361 0.0462
Loa Loa (eye worm) hypothetical protein 0.0489 0.0266 0.0339
Loa Loa (eye worm) TK/FER protein kinase 0.0491 0.0269 0.0342
Echinococcus granulosus activated cdc42 kinase 1 0.1815 0.1701 0.252
Loa Loa (eye worm) hypothetical protein 0.0261 0.002 0.0021
Onchocerca volvulus 0.0879 0.0689 0.0865
Loa Loa (eye worm) hypothetical protein 0.0775 0.0576 0.0739
Echinococcus granulosus 3'partial|retinal guanylyl cyclase 2 0.0261 0.002 0.0024
Schistosoma mansoni tyrosine kinase 0.2308 0.2234 0.5587
Entamoeba histolytica casein kinase, putative 0.0648 0.0439 0.3818
Brugia malayi Guanylyl cyclase protein 23 0.0261 0.002 0.0021
Echinococcus granulosus tyrosine protein kinase csk 0.0261 0.002 0.0024
Echinococcus multilocularis cyclin dependent kinase 9 0.0413 0.0184 0.0184
Toxoplasma gondii AGC kinase 0.0707 0.0503 0.4731
Brugia malayi P38 map kinase family protein 2 0.6472 0.6738 0.8694
Giardia lamblia Kinase, CMGC CDK 0.0488 0.0266 0.2226
Loa Loa (eye worm) hypothetical protein 0.0298 0.006 0.0073
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.1221 0.1059 1
Loa Loa (eye worm) TK/FER protein kinase 0.0491 0.0269 0.0342
Echinococcus granulosus epidermal growth factor receptor 0.107 0.0895 0.1325
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0804 0.0608 0.0608
Entamoeba histolytica hypothetical protein 0.0261 0.002 0.0145
Schistosoma mansoni serine/threonine protein kinase 0.111 0.0938 0.2341
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0804 0.0608 0.0897
Trichomonas vaginalis TKL family protein kinase 0.0261 0.002 0.014
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0335 0.0099 0.0124
Echinococcus multilocularis cyclin dependent kinase 1 0.0488 0.0266 0.0266
Schistosoma mansoni protein kinase 0.0371 0.0139 0.0339
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.3061 0.3049 0.3931
Echinococcus multilocularis mitogen activated protein kinase 11 0.6472 0.6738 0.6738
Leishmania major casein kinase, putative 0.0648 0.0439 0.0647
Echinococcus granulosus slit 2 protein 0.0287 0.0048 0.0067
Brugia malayi hypothetical protein 0.0353 0.012 0.015
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.1502 0.1362 0.1362
Echinococcus multilocularis NCK adaptor protein 0.0427 0.0199 0.0199
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0293 0.0055 0.0076
Echinococcus granulosus tyrosine protein kinase Blk 0.0949 0.0764 0.1129
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.1453 0.1309 0.1309
Schistosoma mansoni protein kinase 0.1335 0.1181 0.295
Schistosoma mansoni growth factor receptor-bound protein 0.0427 0.0199 0.0491
Schistosoma mansoni serine/threonine protein kinase 0.1118 0.0947 0.2362
Loa Loa (eye worm) hypothetical protein 0.0703 0.0498 0.0638
Echinococcus multilocularis dual specificity protein kinase clk2 0.1118 0.0947 0.0947
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0298 0.006 0.0073
Echinococcus multilocularis tyrosine protein kinase pr2 0.0261 0.002 0.002
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.1221 0.1059 0.2643
Schistosoma mansoni protein kinase 0.1709 0.1586 0.3964
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.2338 0.2267 0.2907
Brugia malayi Protein kinase domain containing protein 0.0261 0.002 0.0021
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.1643 0.1515 0.1951
Trypanosoma brucei protein kinase, putative 0.0436 0.0209 0.0305
Schistosoma mansoni protein kinase 0.2551 0.2497 0.6244
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.2076 0.1984 0.2556
Brugia malayi protein-tyrosine kinase 0.0949 0.0764 0.0982
Schistosoma mansoni serine/threonine protein kinase 0.0347 0.0113 0.0274
Entamoeba histolytica protein kinase domain containing protein 0.0261 0.002 0.0145
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.0278 0.0038 0.0052
Giardia lamblia Kinase, CAMK CAMKL 0.0416 0.0188 0.1568
Loa Loa (eye worm) hypothetical protein 0.0298 0.006 0.0073
Echinococcus granulosus tyrosine protein kinase Srms 0.0923 0.0736 0.1087
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0783 0.0585 0.0585
Echinococcus multilocularis tyrosine protein kinase Blk 0.0949 0.0764 0.0764
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0585 0.037 0.3478
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0394 0.0164 0.0164
Schistosoma mansoni tyrosine kinase 0.2202 0.212 0.53
Brugia malayi Fes/CIP4 homology domain containing protein 0.0854 0.0661 0.0849
Echinococcus multilocularis rho associated protein kinase 0.0786 0.0588 0.0588
Trichomonas vaginalis conserved hypothetical protein 0.0261 0.002 0.014
Trichomonas vaginalis CAMK family protein kinase 0.0326 0.009 0.0734
Schistosoma mansoni serine/threonine protein kinase 0.0576 0.0361 0.0896
Trichomonas vaginalis CAMK family protein kinase 0.0375 0.0143 0.1185
Entamoeba histolytica protein kinase, putative 0.0261 0.002 0.0145
Loa Loa (eye worm) hypothetical protein 0.0721 0.0517 0.0663
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0306 0.0068 0.0068
Trichomonas vaginalis CAMK family protein kinase 0.0375 0.0143 0.1185
Loa Loa (eye worm) CMGC/CLK protein kinase 0.1118 0.0947 0.1218
Entamoeba histolytica protein kinase 2, putative 0.0306 0.0068 0.0568
Schistosoma mansoni serine/threonine protein kinase 0.0261 0.002 0.0041
Entamoeba histolytica tyrosine kinase, putative 0.0261 0.002 0.0145
Loa Loa (eye worm) TK protein kinase 0.0261 0.002 0.0021
Loa Loa (eye worm) TK/KIN16 protein kinase 0.3711 0.3752 0.4839
Brugia malayi Protein kinase domain containing protein 0.0434 0.0207 0.0262
Brugia malayi SH2 domain containing protein 0.0491 0.0269 0.0342
Echinococcus multilocularis casein kinase I alpha 0.0648 0.0439 0.0439
Schistosoma mansoni protein kinase 0.0261 0.002 0.0041
Trichomonas vaginalis TKL family protein kinase 0.0261 0.002 0.014
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.13 0.1144 0.1693
Trichomonas vaginalis CMGC family protein kinase 0.0488 0.0266 0.2226
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0261 0.002 0.0145
Trichomonas vaginalis TKL family protein kinase 0.0261 0.002 0.014
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0962 0.0778 0.1001
Echinococcus multilocularis titin 0.0412 0.0183 0.0183
Echinococcus multilocularis dual specificity mitogen activated protein 0.1335 0.1181 0.1181
Echinococcus granulosus tyrosine protein kinase HCK 0.0719 0.0515 0.076
Trichomonas vaginalis TKL family protein kinase 0.0261 0.002 0.014
Schistosoma mansoni protein kinase 0.1007 0.0827 0.2063
Trichomonas vaginalis TKL family protein kinase 0.0261 0.002 0.014
Entamoeba histolytica cell division protein kinase 2, putative 0.0488 0.0266 0.23
Brugia malayi Immunoglobulin I-set domain containing protein 0.0335 0.0099 0.0124
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0436 0.0209 0.0305
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0335 0.0099 0.0099
Brugia malayi Protein kinase domain containing protein 0.7408 0.775 1
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0261 0.002 0.0024
Giardia lamblia Kinase, CMGC CLK 0.1118 0.0947 0.8006
Schistosoma mansoni serine/threonine protein kinase 0.0326 0.009 0.0217
Echinococcus multilocularis phosphorylase kinase gamma subunit 0.0313 0.0077 0.0077
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0518 0.0298 0.0437
Trichomonas vaginalis AGC family protein kinase 0.0804 0.0608 0.5129
Entamoeba histolytica protein kinase, putative 0.0261 0.002 0.0145
Loa Loa (eye worm) TK/EPH protein kinase 0.0347 0.0113 0.0142
Trichomonas vaginalis TKL family protein kinase 0.0261 0.002 0.014
Loa Loa (eye worm) hypothetical protein 0.0763 0.0563 0.0723
Loa Loa (eye worm) hypothetical protein 0.0804 0.0608 0.078
Loa Loa (eye worm) camk/dcamkl protein kinase 0.0299 0.0061 0.0075
Trichomonas vaginalis TKL family protein kinase 0.0261 0.002 0.014
Brugia malayi hypothetical protein 0.0703 0.0498 0.0638
Trichomonas vaginalis TKL family protein kinase 0.0261 0.002 0.014
Trichomonas vaginalis CAMK family protein kinase 0.0367 0.0135 0.1117
Brugia malayi Tyrosine-protein kinase abl-1 0.1413 0.1266 0.163
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.1007 0.0827 0.1063
Schistosoma mansoni serine/threonine protein kinase 0.1786 0.1669 0.4171
Echinococcus granulosus cyclin dependent kinase 7 0.066 0.0452 0.0666
Echinococcus multilocularis G protein coupled receptor kinase 6 0.1496 0.1356 0.1356
Schistosoma mansoni protein kinase 0.2551 0.2497 0.6244
Echinococcus multilocularis serine:threonine protein kinase N2 0.0576 0.0361 0.0361
Entamoeba histolytica serine/threonine protein kinase, putative 0.0375 0.0143 0.1224
Loa Loa (eye worm) hypothetical protein 0.0788 0.059 0.0757
Brugia malayi Protein kinase domain containing protein 0.0366 0.0133 0.0167
Echinococcus granulosus tyrosine protein kinase Fes:Fps 0.0261 0.002 0.0024
Entamoeba histolytica hypothetical protein 0.0261 0.002 0.0145
Trichomonas vaginalis TKL family protein kinase 0.0261 0.002 0.014
Brugia malayi protein unc-22 0.0412 0.0183 0.0232
Trichomonas vaginalis AGC family protein kinase 0.0651 0.0442 0.3723
Schistosoma mansoni hypothetical protein 0.0353 0.012 0.0291
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0261 0.002 0.0145
Trichomonas vaginalis conserved hypothetical protein 0.0261 0.002 0.014
Loa Loa (eye worm) STE/STE7/MEK1 protein kinase 0.1335 0.1181 0.1521
Brugia malayi Protein kinase domain containing protein 0.0261 0.002 0.0021
Echinococcus granulosus calcium dependent protein kinase 0.041 0.0182 0.0265
Entamoeba histolytica protein kinase domain containing protein 0.0651 0.0442 0.3846
Brugia malayi Dual specificity mitogen-activated protein kinase kinase mek-2 0.1335 0.1181 0.1521
Trichomonas vaginalis TKL family protein kinase 0.0261 0.002 0.014
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.13 0.1144 0.1472
Leishmania major protein kinase, putative 0.0585 0.037 0.0545
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.0287 0.0048 0.0057
Echinococcus granulosus serine:threonine protein kinase 0.0346 0.0112 0.0161
Echinococcus granulosus glycogen synthase kinase 3 beta 0.1221 0.1059 0.1567
Echinococcus multilocularis kinase suppressor of Ras 1 0.0261 0.002 0.002
Trichomonas vaginalis AGC family protein kinase 0.0754 0.0553 0.4666
Entamoeba histolytica protein kinase, putative 0.0707 0.0503 0.4378
Plasmodium vivax casein kinase 1, putative 0.0648 0.0439 0.4126
Loa Loa (eye worm) TK protein kinase 0.0949 0.0764 0.0982
Echinococcus multilocularis tyrosine protein kinase Fyn 0.1129 0.0959 0.0959
Echinococcus granulosus Immunoglobulin 0.0666 0.0458 0.0675
Echinococcus granulosus hemicentin 1 0.0298 0.006 0.0084
Loa Loa (eye worm) hypothetical protein 0.0951 0.0766 0.0985
Trichomonas vaginalis TKL family protein kinase 0.0261 0.002 0.014
Brugia malayi Protein kinase domain containing protein 0.0811 0.0615 0.0789
Echinococcus multilocularis tyrosine protein kinase Srms 0.0949 0.0764 0.0764
Onchocerca volvulus 0.0474 0.025 0.0298
Entamoeba histolytica hypothetical protein 0.0264 0.0023 0.0175
Echinococcus multilocularis hemicentin 1 0.0298 0.006 0.006
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0261 0.002 0.0041
Schistosoma mansoni serine/threonine protein kinase 0.0651 0.0442 0.1098
Trichomonas vaginalis AGC family protein kinase 0.0754 0.0553 0.4666
Echinococcus granulosus neuroglian 0.0335 0.0099 0.0143
Echinococcus multilocularis neurotracting:lsamp:neurotrimin:obcam 0.0298 0.006 0.006
Loa Loa (eye worm) hypothetical protein 0.0346 0.0112 0.014
Trichomonas vaginalis TKL family protein kinase 0.0261 0.002 0.014
Brugia malayi Immunoglobulin I-set domain containing protein 0.0412 0.0183 0.0232
Entamoeba histolytica protein kinase, putative 0.0261 0.002 0.0145
Echinococcus granulosus serine:threonine kinase SAD 1 0.0375 0.0143 0.0207
Trichomonas vaginalis CMGC family protein kinase 0.0488 0.0266 0.2226
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0306 0.0068 0.0614
Plasmodium falciparum calcium-dependent protein kinase 4 0.0585 0.037 0.3478
Entamoeba histolytica protein kinase, putative 0.0261 0.002 0.0145
Loa Loa (eye worm) TK/FER protein kinase 0.0491 0.0269 0.0342
Trypanosoma brucei protein kinase, putative 0.1221 0.1059 0.1567
Echinococcus granulosus tyrosine kinase 0.0261 0.002 0.0024
Trichomonas vaginalis CAMK family protein kinase 0.0375 0.0143 0.1185
Echinococcus granulosus ephrin type A receptor 4 A 0.0329 0.0093 0.0133
Trichomonas vaginalis TKL family protein kinase 0.0261 0.002 0.014
Schistosoma mansoni neuroglian 0.0335 0.0099 0.0241
Onchocerca volvulus 0.0648 0.0439 0.0542
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0648 0.0439 0.0562
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0278 0.0038 0.0038
Schistosoma mansoni serine/threonine protein kinase 0.066 0.0452 0.1124
Loa Loa (eye worm) hypothetical protein 0.0314 0.0077 0.0095
Giardia lamblia Kinase, CAMK CAMKL 0.0416 0.0188 0.1568
Entamoeba histolytica protein kinase domain containing protein 0.031 0.0073 0.0608
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0261 0.002 0.0021
Echinococcus granulosus N chimaerin 0.0393 0.0163 0.0237
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0651 0.0442 0.0442
Plasmodium falciparum calcium-dependent protein kinase 3 0.0585 0.037 0.3478
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.1076 0.0902 0.1334
Echinococcus multilocularis protein kinase shaggy 0.1221 0.1059 0.1059
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0335 0.0099 0.0143
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0436 0.0209 0.0305
Schistosoma mansoni serine/threonine protein kinase 0.0783 0.0585 0.1456
Echinococcus granulosus serine/threonine protein kinase 0.0352 0.0118 0.0171
Trichomonas vaginalis TKL family protein kinase 0.0261 0.002 0.014
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0585 0.037 0.3478
Loa Loa (eye worm) TK/ALK protein kinase 0.5237 0.5402 0.6969
Brugia malayi hypothetical protein 0.0491 0.0269 0.0342
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0585 0.037 0.0474
Echinococcus multilocularis natriuretic peptide receptor 1 0.0261 0.002 0.002
Entamoeba histolytica cell division protein kinase 2, putative 0.053 0.0311 0.2696
Plasmodium vivax protein kinase Crk2 0.0488 0.0266 0.2485
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.1129 0.0959 0.0959
Trichomonas vaginalis TKL family protein kinase 0.0261 0.002 0.014
Trichomonas vaginalis CMGC family protein kinase 0.0287 0.0048 0.0378
Echinococcus granulosus retinal guanylyl cyclase 2 0.0261 0.002 0.0024
Trichomonas vaginalis STE family protein kinase 0.0394 0.0164 0.136
Entamoeba histolytica protein kinase, putative 0.0754 0.0553 0.482
Schistosoma mansoni serine/threonine protein kinase 0.1643 0.1515 0.3785
Schistosoma mansoni serine/threonine protein kinase 0.0576 0.0361 0.0896
Loa Loa (eye worm) CMGC/CDK/CDK7 protein kinase 0.066 0.0452 0.0579
Schistosoma mansoni vesicular amine transporter 0.0666 0.0458 0.1139
Schistosoma mansoni cell adhesion molecule 0.0335 0.0099 0.0241
Echinococcus multilocularis aurora kinase A 0.0651 0.0442 0.0442
Echinococcus multilocularis atrial natriuretic peptide receptor 1 0.0261 0.002 0.002
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0393 0.0163 0.0237
Loa Loa (eye worm) hypothetical protein 0.0788 0.059 0.0757
Loa Loa (eye worm) TKL/STKR/TYPE2 protein kinase 0.0811 0.0615 0.0789
Schistosoma mansoni protein kinase 0.0436 0.0209 0.0514
Brugia malayi Immunoglobulin I-set domain containing protein 0.0335 0.0099 0.0124
Trypanosoma cruzi casein kinase, putative 0.0648 0.0439 0.0647
Echinococcus granulosus casein kinase I alpha 0.0648 0.0439 0.0647
Loa Loa (eye worm) hypothetical protein 0.0551 0.0334 0.0427
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0804 0.0608 0.0897
Echinococcus multilocularis serine:threonine protein kinase 38 0.0576 0.0361 0.0361
Echinococcus granulosus cyclin dependent kinase 9 0.0454 0.0229 0.0335
Brugia malayi casein kinase 1, delta 0.0648 0.0439 0.0562
Echinococcus granulosus casein kinase I alpha 0.0648 0.0439 0.0647
Trichomonas vaginalis TKL family protein kinase 0.0261 0.002 0.014
Schistosoma mansoni serine/threonine protein kinase 0.0518 0.0298 0.0737
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0509 0.0288 0.0368
Echinococcus granulosus titin 0.0412 0.0183 0.0267
Echinococcus granulosus protein kinase shaggy 0.1221 0.1059 0.1567
Brugia malayi EGF-like domain containing protein 0.0287 0.0048 0.0058
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.2551 0.2497 0.2497
Echinococcus granulosus casein kinase I alpha 0.0648 0.0439 0.0647
Plasmodium falciparum calcium-dependent protein kinase 1 0.0585 0.037 0.3478
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0804 0.0608 0.5725
Echinococcus multilocularis tyrosine protein kinase csk 0.0261 0.002 0.002
Brugia malayi probable protein kinase 0.1709 0.1586 0.2043
Onchocerca volvulus 0.039 0.0159 0.018
Trypanosoma cruzi casein kinase, putative 0.0648 0.0439 0.0647
Echinococcus granulosus tyrosine protein kinase Src64B 0.1129 0.0959 0.1418
Echinococcus multilocularis N chimaerin 0.0393 0.0163 0.0163
Plasmodium falciparum glycogen synthase kinase 3 0.1221 0.1059 1
Brugia malayi Protein kinase domain containing protein 0.048 0.0257 0.0327
Echinococcus multilocularis insulin receptor 0.1456 0.1313 0.1313
Onchocerca volvulus 0.7408 0.775 1
Echinococcus granulosus MAM 0.0353 0.012 0.0173
Brugia malayi Homeodomain interacting protein kinase protein 1 0.0354 0.0121 0.0152
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0393 0.0163 0.0163
Trichomonas vaginalis CAMK family protein kinase 0.0375 0.0143 0.1185
Loa Loa (eye worm) hypothetical protein 0.0353 0.012 0.015
Echinococcus granulosus c src tyrosine kinase 0.0671 0.0463 0.0683
Brugia malayi Variant SH3 domain containing protein 0.041 0.0181 0.0229
Entamoeba histolytica ankyrin repeat protein 0.0261 0.002 0.0145
Entamoeba histolytica PH domain containing protein kinase, putative 0.0851 0.0658 0.574
Loa Loa (eye worm) TK/FER protein kinase 0.0261 0.002 0.0021
Schistosoma mansoni serine/threonine protein kinase 0.0282 0.0043 0.0099
Entamoeba histolytica tyrosine kinase, putative 0.0261 0.002 0.0145
Entamoeba histolytica protein kinase domain containing protein 0.0261 0.002 0.0145
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0375 0.0143 0.0143
Giardia lamblia Kinase, NEK 0.0284 0.0045 0.035
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.1502 0.1362 0.2017
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.0721 0.0517 0.0763
Loa Loa (eye worm) hypothetical protein 0.0335 0.0099 0.0124
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0375 0.0143 0.018
Echinococcus multilocularis leucine rich repeat serine:threonine protein 0.048 0.0257 0.0257
Onchocerca volvulus 0.0284 0.0045 0.0032
Leishmania major protein kinase, putative 0.0651 0.0442 0.0651
Trypanosoma cruzi cdc2-related kinase 1 0.0488 0.0266 0.0389
Leishmania major hypothetical protein, conserved 0.0261 0.002 0.0024
Echinococcus multilocularis tyrosine protein kinase Fyn 0.1129 0.0959 0.0959
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.13 0.1144 0.1693
Onchocerca volvulus 0.0491 0.0269 0.0322
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.111 0.0938 0.0938
Brugia malayi Protein kinase domain containing protein 0.0261 0.002 0.0021
Loa Loa (eye worm) hypothetical protein 0.0879 0.0689 0.0885
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0287 0.0048 0.0066
Trichomonas vaginalis TKL family protein kinase 0.0261 0.002 0.014
Brugia malayi hypothetical protein 0.2911 0.2887 0.3722
Echinococcus multilocularis macrophage colony stimulating factor 1 receptor 0.0261 0.002 0.002
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0707 0.0503 0.0645
Brugia malayi hypothetical protein 0.0637 0.0426 0.0546
Echinococcus granulosus mitogen activated protein kinase 14 0.6472 0.6738 1
Entamoeba histolytica protein kinase domain containing protein 0.0261 0.002 0.0145
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0666 0.0458 0.0458
Entamoeba histolytica hypothetical protein 0.0261 0.002 0.0145
Schistosoma mansoni protein kinase 0.2513 0.2456 0.6142
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.2338 0.2267 0.3361
Brugia malayi Immunoglobulin I-set domain containing protein 0.1702 0.1579 0.2034
Trichomonas vaginalis CMGC family protein kinase 0.1221 0.1059 0.8958
Trichomonas vaginalis TKL family protein kinase 0.0261 0.002 0.014
Brugia malayi Protein kinase domain containing protein 0.0261 0.002 0.0021
Echinococcus granulosus cyclin dependent kinase 19 0.1813 0.1699 0.2517
Leishmania major protein kinase, putative 0.1118 0.0947 0.1401
Entamoeba histolytica hypothetical protein 0.0261 0.002 0.0145
Loa Loa (eye worm) STE/STE20/SLK protein kinase 0.0344 0.011 0.0137
Echinococcus granulosus beta-adrenergic receptor kinase 0.0321 0.0085 0.0122
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.1221 0.1059 0.1567
Entamoeba histolytica protein kinase, putative 0.0261 0.002 0.0145
Loa Loa (eye worm) CAMK/PIM protein kinase 0.2338 0.2267 0.2922
Echinococcus multilocularis casein kinase I delta 0.0648 0.0439 0.0439
Trichomonas vaginalis TKL family protein kinase 0.0261 0.002 0.014
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.1118 0.0947 0.1401
Trichomonas vaginalis TKL family protein kinase 0.0261 0.002 0.014
Trichomonas vaginalis TKL family protein kinase 0.0261 0.002 0.014
Trichomonas vaginalis TKL family protein kinase 0.0261 0.002 0.014
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0335 0.0099 0.0099
Brugia malayi Protein kinase domain containing protein 0.0488 0.0266 0.0339
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0804 0.0608 0.078
Schistosoma mansoni protein kinase 0.0261 0.002 0.0041
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.2096 0.2005 0.2972
Echinococcus multilocularis epidermal growth factor receptor 0.107 0.0895 0.0895
Loa Loa (eye worm) thyroid receptor interactor 0.0854 0.0661 0.0849
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0261 0.002 0.0145
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.0261 0.002 0.0021
Echinococcus multilocularis casein kinase I alpha 0.0648 0.0439 0.0439
Giardia lamblia Kinase, STE STE20 0.1335 0.1181 1
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0436 0.0209 0.1945
Entamoeba histolytica tyrosine kinase, putative 0.0261 0.002 0.0145
Entamoeba histolytica protein kinase, putative 0.0394 0.0164 0.1405
Loa Loa (eye worm) TKL/MLK/TAK1 protein kinase 0.0261 0.002 0.0021
Loa Loa (eye worm) TK/FER protein kinase 0.0491 0.0269 0.0342
Entamoeba histolytica serine/threonine kinase, putative 0.0261 0.002 0.0145
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0394 0.0164 0.0238
Trichomonas vaginalis AGC family protein kinase 0.0623 0.0411 0.3463
Schistosoma mansoni protein tyrosine kinase 0.0261 0.002 0.0041
Giardia lamblia Kinase, NEK 0.0261 0.002 0.014
Brugia malayi hypothetical protein 0.0261 0.002 0.0021
Echinococcus granulosus cyclin dependent kinase 5 0.0488 0.0266 0.0389
Schistosoma mansoni serine/threonine protein kinase 0.1813 0.1699 0.4245
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0804 0.0608 0.0608
Echinococcus granulosus NDR protein kinase 0.0576 0.0361 0.0531
Brugia malayi Protein kinase domain containing protein 0.0576 0.0361 0.0462
Entamoeba histolytica protein kinase, putative 0.0287 0.0048 0.039
Trypanosoma cruzi aurora B kinase, putative 0.0651 0.0442 0.0651
Trypanosoma brucei aurora B kinase 0.0651 0.0442 0.0651
Loa Loa (eye worm) AGC/PKG protein kinase 0.0282 0.0043 0.0051
Echinococcus granulosus fibroblast growth factor receptor 4 0.1502 0.1362 0.2017
Plasmodium falciparum NIMA related kinase 1 0.0284 0.0045 0.0391
Entamoeba histolytica tyrosin kinase, putative 0.031 0.0073 0.0608
Loa Loa (eye worm) TK/ACK protein kinase 0.0261 0.002 0.0021
Entamoeba histolytica protein kinase domain containing protein 0.0261 0.002 0.0145
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0488 0.0266 0.0339
Echinococcus multilocularis protein kinase c iota type 0.0828 0.0633 0.0633
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.1129 0.0959 0.1418
Echinococcus multilocularis c src tyrosine kinase 0.0671 0.0463 0.0463
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.1118 0.0947 0.1401
Brugia malayi Doublecortin family protein 0.0299 0.0061 0.0075
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.0375 0.0143 0.0207
Entamoeba histolytica receptor protein kinase, putative 0.0261 0.002 0.0145
Echinococcus multilocularis activated cdc42 kinase 1 0.1815 0.1701 0.1701
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0585 0.037 0.037
Echinococcus granulosus cyclin dependent kinase 0.0488 0.0266 0.0389
Trichomonas vaginalis CMGC family protein kinase 0.0287 0.0048 0.0378
Entamoeba histolytica protein kinase domain containing protein 0.1221 0.1059 0.9255
Loa Loa (eye worm) TK/KIN6 protein kinase 0.0261 0.002 0.0021
Trichomonas vaginalis STE family protein kinase 0.1335 0.1181 1
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0261 0.002 0.0021
Entamoeba histolytica protein kinase with ankyrin repeats, putative 0.0261 0.002 0.0145
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0282 0.0043 0.0374
Echinococcus multilocularis serine:threonine protein kinase receptor R3 0.0921 0.0734 0.0734
Trichomonas vaginalis protein tyrosine kinase, putative 0.0261 0.002 0.014
Brugia malayi Serine/threonine-protein kinase Pim-3 0.2338 0.2267 0.2922
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0585 0.037 0.037
Loa Loa (eye worm) TK/FER protein kinase 0.0261 0.002 0.0021
Brugia malayi Cam kinase protein 1 0.0585 0.037 0.0474
Schistosoma mansoni serine/threonine protein kinase 0.1076 0.0902 0.225
Brugia malayi Protein kinase domain containing protein 0.3981 0.4044 0.5216
Loa Loa (eye worm) hypothetical protein 0.0637 0.0426 0.0546
Loa Loa (eye worm) hypothetical protein 0.1003 0.0823 0.1058
Trichomonas vaginalis AGC family protein kinase 0.0261 0.002 0.014
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0393 0.0163 0.04
Brugia malayi Immunoglobulin I-set domain containing protein 0.0298 0.006 0.0073
Brugia malayi Protein kinase domain containing protein 0.0261 0.002 0.0021
Brugia malayi ephrin receptor 1 precursor 0.0293 0.0054 0.0066
Echinococcus granulosus tyrosine kinase 0.0491 0.0269 0.0394
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.1221 0.1059 0.1059
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0488 0.0266 0.0389
Loa Loa (eye worm) hypothetical protein 0.0277 0.0037 0.0043
Schistosoma mansoni septate junction protein 0.0298 0.006 0.0142
Echinococcus granulosus cGMP dependent protein kinase 1 0.0282 0.0043 0.0059
Entamoeba histolytica tyrosine- protein kinase 2, putative 0.0261 0.002 0.0145
Trichomonas vaginalis CAMK family protein kinase 0.0326 0.009 0.0734
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0261 0.002 0.0024
Echinococcus granulosus titin 0.0412 0.0183 0.0267
Entamoeba histolytica tyrosine kinase, putative 0.0261 0.002 0.0145
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.0721 0.0517 0.0517
Brugia malayi C1-like domain containing protein 0.1126 0.0955 0.1229
Loa Loa (eye worm) hypothetical protein 0.0879 0.0689 0.0885
Schistosoma mansoni tyrosine kinase 0.1129 0.0959 0.2392
Entamoeba histolytica tyrosine kinase, putative 0.0261 0.002 0.0145
Trichomonas vaginalis TKL family protein kinase 0.0261 0.002 0.014
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0261 0.002 0.0041
Echinococcus granulosus tyrosine protein kinase otk 0.0298 0.006 0.0084
Schistosoma mansoni serine/threonine protein kinase 0.0648 0.0439 0.109
Trichomonas vaginalis CMGC family protein kinase 0.0287 0.0048 0.0378
Loa Loa (eye worm) AGC/PKA protein kinase 0.0804 0.0608 0.078
Schistosoma mansoni tyrosine kinase 0.0261 0.002 0.0041
Plasmodium falciparum tyrosine kinase-like protein 0.0261 0.002 0.0156
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0923 0.0736 0.1088
Leishmania major protein kinase, putative 0.1118 0.0947 0.1401
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.0412 0.0183 0.0232
Schistosoma mansoni septate junction protein 0.0298 0.006 0.0142
Plasmodium vivax protein kinase, putative 0.0277 0.0037 0.032
Trichomonas vaginalis CMGC family protein kinase 0.0287 0.0048 0.0378
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.2471 0.2411 0.2411
Brugia malayi Protein kinase domain containing protein 0.0491 0.0269 0.0342
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0261 0.002 0.002
Echinococcus multilocularis serine:threonine protein kinase N2 0.1786 0.1669 0.1669
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.1126 0.0955 0.1229
Trypanosoma cruzi protein kinase, putative 0.0261 0.002 0.0024
Schistosoma mansoni ephrin receptor 0.0297 0.0059 0.014
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0812 0.0616 0.091
Loa Loa (eye worm) hypothetical protein 0.0298 0.006 0.0073
Brugia malayi Stress-activated protein kinase jnk-1 0.3061 0.3049 0.3931
Schistosoma mansoni tyrosine kinase 0.1129 0.0959 0.2392
Trichomonas vaginalis CAMK family protein kinase 0.0346 0.0112 0.0919
Brugia malayi Protein kinase domain containing protein 0.0261 0.002 0.0021
Entamoeba histolytica protein kinase, putative 0.0651 0.0442 0.3846
Onchocerca volvulus Slit protein homolog 0.0287 0.0048 0.0037
Echinococcus granulosus roundabout 2 0.1001 0.082 0.1213
Entamoeba histolytica protein kinase domain containing protein 0.0261 0.002 0.0145
Loa Loa (eye worm) TKL/LRRK protein kinase 0.048 0.0257 0.0327
Loa Loa (eye worm) protein kinase domain-containing protein 0.0261 0.002 0.0021
Trypanosoma brucei Pseudokinase, putative 0.0261 0.002 0.0024
Brugia malayi Immunoglobulin I-set domain containing protein 0.0298 0.006 0.0073
Loa Loa (eye worm) hypothetical protein 0.0287 0.0048 0.0058
Onchocerca volvulus 0.0611 0.0399 0.049
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.1076 0.0902 0.116
Loa Loa (eye worm) hypothetical protein 0.1554 0.1419 0.1827
Brugia malayi RhoGAP domain containing protein 0.0393 0.0163 0.0206
Schistosoma mansoni tyrosine kinase 0.0261 0.002 0.0041
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0763 0.0563 0.0831
Schistosoma mansoni serine/threonine protein kinase 0.1118 0.0947 0.2362
Echinococcus multilocularis hemicentin 1 0.0298 0.006 0.006
Schistosoma mansoni ste20-related kinase 0.0357 0.0124 0.0301
Trichomonas vaginalis TKL family protein kinase 0.0261 0.002 0.014
Echinococcus multilocularis tyrosine protein kinase ABL1 0.2432 0.2369 0.2369
Brugia malayi Protein kinase domain containing protein 0.1813 0.1699 0.2188
Trichomonas vaginalis TKL family protein kinase 0.0261 0.002 0.014
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0804 0.0608 0.5725
Trichomonas vaginalis TKL family protein kinase 0.0261 0.002 0.014
Echinococcus granulosus tyrosine protein kinase csk 0.0261 0.002 0.0024
Loa Loa (eye worm) hypothetical protein 0.1125 0.0955 0.1228
Echinococcus multilocularis ephrin type A receptor 4 A 0.0329 0.0093 0.0093
Loa Loa (eye worm) hypothetical protein 0.0703 0.0498 0.0638
Entamoeba histolytica tyrosine kinase, putative 0.0261 0.002 0.0145
Onchocerca volvulus Serine\/threonine kinase homolog 0.0313 0.0077 0.0073
Loa Loa (eye worm) TK/FER protein kinase 0.0491 0.0269 0.0342
Echinococcus granulosus cGMP dependent protein kinase 0.0282 0.0043 0.0059
Trypanosoma brucei Flagellum attachment zone protein 20 0.0261 0.002 0.0024
Trichomonas vaginalis TKL family protein kinase 0.0261 0.002 0.014
Trichomonas vaginalis CK1 family protein kinase 0.0648 0.0439 0.3696
Loa Loa (eye worm) hypothetical protein 0.0703 0.0498 0.0638
Loa Loa (eye worm) TK/DDR protein kinase 0.0261 0.002 0.0021
Brugia malayi Protein kinase domain containing protein 0.13 0.1144 0.1472
Loa Loa (eye worm) TK protein kinase 0.0261 0.002 0.0021
Brugia malayi Temporarily assigned gene name protein 59 0.0721 0.0517 0.0663
Trypanosoma cruzi casein kinase, putative 0.0648 0.0439 0.0647
Brugia malayi Protein kinase domain containing protein 0.0261 0.002 0.0021
Trichomonas vaginalis TKL family protein kinase 0.0261 0.002 0.014
Entamoeba histolytica PH domain containing protein kinase, putative 0.0352 0.0118 0.101
Trichomonas vaginalis CAMK family protein kinase 0.0262 0.002 0.0146
Brugia malayi SRC-1 0.1129 0.0959 0.1233
Loa Loa (eye worm) serine/threonine protein kinase 0.0261 0.002 0.0021
Echinococcus multilocularis tyrosine protein kinase csk 0.0261 0.002 0.002
Brugia malayi Protein kinase domain containing protein 0.0464 0.0239 0.0305
Schistosoma mansoni cell adhesion molecule 0.0335 0.0099 0.0241
Echinococcus granulosus homeodomain interacting protein kinase 3 0.0354 0.0121 0.0174
Trichomonas vaginalis CAMK family protein kinase 0.0375 0.0143 0.1185
Echinococcus granulosus activated cdc42 kinase 1 0.1815 0.1701 0.252
Loa Loa (eye worm) hypothetical protein 0.0551 0.0334 0.0427
Loa Loa (eye worm) CMGC/CDK/CDK8 protein kinase 0.1813 0.1699 0.2188
Trichomonas vaginalis serine/threonine-protein kinase wnk, putative 0.0261 0.002 0.014
Entamoeba histolytica tyrosine kinase, putative 0.0261 0.002 0.0145
Trichomonas vaginalis CAMK family protein kinase 0.0375 0.0143 0.1185
Schistosoma mansoni nephrin 0.0335 0.0099 0.0241
Schistosoma mansoni hypothetical protein 0.0721 0.0517 0.1287
Loa Loa (eye worm) TK/RYK protein kinase 0.0261 0.002 0.0021
Echinococcus multilocularis calcium activated potassium channel 0.0347 0.0113 0.0113
Loa Loa (eye worm) RGC/RGC protein kinase 0.0261 0.002 0.0021
Trichomonas vaginalis CAMK family protein kinase 0.0375 0.0143 0.1185
Loa Loa (eye worm) CAMK/PHK protein kinase 0.0313 0.0077 0.0095
Entamoeba histolytica hypothetical protein 0.0261 0.002 0.0145
Toxoplasma gondii protein kinase 0.0261 0.002 0.0156
Entamoeba histolytica protein kinase, putative 0.0261 0.002 0.0145
Schistosoma mansoni serine/threonine kinase 0.0475 0.0252 0.0622
Schistosoma mansoni titin 0.0412 0.0183 0.045
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0518 0.0298 0.0437
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0721 0.0517 0.0763
Trichomonas vaginalis TKL family protein kinase 0.0261 0.002 0.014
Echinococcus multilocularis rac serine:threonine kinase 0.0352 0.0118 0.0118
Echinococcus multilocularis cyclin dependent kinase 19 0.1813 0.1699 0.1699
Schistosoma mansoni serine/threonine protein kinase 0.0321 0.0085 0.0205
Plasmodium falciparum protein serine/threonine kinase-1 0.1118 0.0947 0.8937
Echinococcus granulosus tyrosine protein kinase Src42A 0.0705 0.05 0.0737
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0585 0.037 0.0545
Brugia malayi Sex muscle abnormal protein 5 0.041 0.0181 0.0229
Loa Loa (eye worm) CMGC/CDK/CDK9 protein kinase 0.0413 0.0184 0.0233
Trichomonas vaginalis AGC family protein kinase 0.0754 0.0553 0.4666
Echinococcus granulosus tyrosine protein kinase shark 0.0717 0.0513 0.0757
Loa Loa (eye worm) hypothetical protein 0.0721 0.0517 0.0663
Entamoeba histolytica PH domain containing protein kinase, putative 0.0851 0.0658 0.574
Loa Loa (eye worm) TK protein kinase 0.0719 0.0515 0.0661
Entamoeba histolytica PH domain containing protein kinase, putative 0.0352 0.0118 0.101
Brugia malayi integrin-linked kinase 0.0261 0.002 0.0021
Schistosoma mansoni vav2 0.044 0.0213 0.0526
Brugia malayi hypothetical protein 0.0721 0.0517 0.0663
Brugia malayi Protein kinase domain containing protein 0.0261 0.002 0.0021
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0287 0.0048 0.0066
Trichomonas vaginalis conserved hypothetical protein 0.0261 0.002 0.014
Echinococcus multilocularis serine:threonine protein kinase N2 0.1209 0.1046 0.1046
Trichomonas vaginalis CAMK family protein kinase 0.0262 0.002 0.0146
Echinococcus multilocularis mitogen activated protein kinase 14 0.6472 0.6738 0.6738
Plasmodium vivax tyrosine kinase-like protein, putative 0.0261 0.002 0.0156
Echinococcus multilocularis transfer RNA-Thr 0.1815 0.1701 0.1701
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0394 0.0164 0.0238
Brugia malayi Protein kinase domain 0.0394 0.0164 0.0207
Entamoeba histolytica protein kinase, putative 0.0261 0.002 0.0145
Trichomonas vaginalis TKL family protein kinase 0.0261 0.002 0.014
Echinococcus multilocularis expressed conserved protein 0.0282 0.0043 0.0043
Echinococcus granulosus insulin receptor 0.1456 0.1313 0.1944
Schistosoma mansoni serine/threonine protein kinase 0.0375 0.0143 0.035
Loa Loa (eye worm) hypothetical protein 0.0298 0.006 0.0073
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0261 0.002 0.0156
Loa Loa (eye worm) TK/FER protein kinase 0.0261 0.002 0.0021
Loa Loa (eye worm) hypothetical protein 0.0298 0.006 0.0073
Echinococcus multilocularis tyrosine protein kinase Fyn 0.1129 0.0959 0.0959
Entamoeba histolytica hypothetical protein 0.0264 0.0023 0.0175
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.0615 0.0403 0.0515
Loa Loa (eye worm) TK protein kinase 0.0261 0.002 0.0021
Echinococcus granulosus serine threonine protein kinase nrc 0.0306 0.0068 0.0096
Entamoeba histolytica serine/threonine kinase, putative 0.0261 0.002 0.0145
Echinococcus multilocularis homeodomain interacting protein kinase 3 0.0354 0.0121 0.0121
Giardia lamblia Kinase, CK1 Casein kinase 0.0648 0.0439 0.3696
Trichomonas vaginalis AGC family protein kinase 0.0284 0.0045 0.035
Echinococcus multilocularis fibroblast growth factor receptor 4 0.1502 0.1362 0.1362
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0721 0.0517 0.0763
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.1129 0.0959 0.0959
Brugia malayi Protein kinase domain containing protein 0.2076 0.1984 0.2556
Brugia malayi cyclin-dependent kinase 7 homolog 0.0702 0.0497 0.0637
Brugia malayi Fibronectin type III domain containing protein 0.0703 0.0498 0.0638
Schistosoma mansoni protein kinase 0.2551 0.2497 0.6244
Trichomonas vaginalis STE family protein kinase 0.1335 0.1181 1
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0804 0.0608 0.5725
Echinococcus multilocularis tyrosine kinase 0.0261 0.002 0.002
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.1129 0.0959 0.0959
Schistosoma mansoni titin 0.0298 0.006 0.0142
Giardia lamblia Kinase, AGC PKA 0.0804 0.0608 0.5129
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.063 0.0419 0.0419
Echinococcus multilocularis tyrosine protein kinase HCK 0.0719 0.0515 0.0515
Echinococcus granulosus serine:threonine protein kinase mig 15 0.1534 0.1397 0.207
Echinococcus granulosus protein kinase C gamma type 0.062 0.0408 0.0601
Onchocerca volvulus 0.0998 0.0817 0.1031
Loa Loa (eye worm) hypothetical protein 0.0298 0.006 0.0073
Echinococcus granulosus serine:threonine protein kinase N2 0.1786 0.1669 0.2473
Brugia malayi Protein kinase domain containing protein 0.0261 0.002 0.0021
Echinococcus multilocularis heat shock protein 70 0.0261 0.002 0.002
Onchocerca volvulus 0.0412 0.0183 0.0211
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.2096 0.2005 0.2005
Echinococcus multilocularis serine:threonine protein kinase 0.0346 0.0112 0.0112
Schistosoma mansoni serine/threonine protein kinase 0.3061 0.3049 0.7627
Trichomonas vaginalis CAMK family protein kinase 0.0375 0.0143 0.1185
Entamoeba histolytica hypothetical protein, conserved 0.0261 0.002 0.0145
Schistosoma mansoni serine/threonine protein kinase 0.0375 0.0143 0.035
Loa Loa (eye worm) hypothetical protein 0.0261 0.002 0.0021
Onchocerca volvulus 0.0355 0.0121 0.0131
Trypanosoma cruzi cdc2-related kinase 3 0.0488 0.0266 0.0389
Echinococcus multilocularis tyrosine protein kinase shark 0.0717 0.0513 0.0513
Toxoplasma gondii aurora kinase 0.0651 0.0442 0.4156
Echinococcus granulosus NCK adaptor protein 0.041 0.0181 0.0264
Loa Loa (eye worm) TK/FER protein kinase 0.0491 0.0269 0.0342
Echinococcus multilocularis tyrosine protein kinase Fes:Fps 0.0261 0.002 0.002
Echinococcus granulosus tyrosine protein kinase Btk29A 0.2471 0.2411 0.3574
Trypanosoma cruzi cdc2-related kinase 1 0.0488 0.0266 0.0389
Loa Loa (eye worm) CMGC/DYRK/HIPK protein kinase 0.0354 0.0121 0.0152
Echinococcus multilocularis roundabout 2 0.1001 0.082 0.082
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0651 0.0442 0.3846
Echinococcus multilocularis peroxidasin 0.0301 0.0063 0.0063
Entamoeba histolytica tyrosine kinase, putative 0.0261 0.002 0.0145
Trypanosoma cruzi casein kinase, putative 0.0648 0.0439 0.0647
Onchocerca volvulus 0.0491 0.0269 0.0322
Loa Loa (eye worm) RGC/RGC protein kinase 0.0261 0.002 0.0021
Brugia malayi putative serine/threonine kinase SADA gamma 0.0375 0.0143 0.018
Brugia malayi Protein kinase domain containing protein 0.0352 0.0119 0.0149
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0261 0.002 0.0145
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.0287 0.0048 0.0066
Entamoeba histolytica protein kinase domain containing protein 0.0354 0.0121 0.103
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0306 0.0068 0.0096
Entamoeba histolytica tyrosine kinase, putative 0.0261 0.002 0.0145
Brugia malayi intracellular kinase 0.1221 0.1059 0.1362
Echinococcus multilocularis casein kinase ii subunit alpha 0.0246 0.0003 0.0003
Plasmodium falciparum serine/threonine protein kinase, putative 0.0651 0.0442 0.4156
Trichomonas vaginalis STE family protein kinase 0.0284 0.0045 0.035
Brugia malayi Immunoglobulin I-set domain containing protein 0.3711 0.3752 0.4839
Echinococcus granulosus cyclin dependent kinase 9 0.0413 0.0184 0.0268
Entamoeba histolytica serine/threonine protein kinase, putative 0.0326 0.009 0.0758
Loa Loa (eye worm) TK/EGFR protein kinase 0.107 0.0895 0.1151
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0284 0.0045 0.0391
Trichomonas vaginalis TKL family protein kinase 0.0261 0.002 0.014
Brugia malayi p70 ribosomal S6 kinase beta 0.0707 0.0503 0.0645
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.0988 0.0806 0.1037
Echinococcus multilocularis STE20 serine:threonine protein kinase 0.0663 0.0455 0.0455
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0375 0.0143 0.0207
Loa Loa (eye worm) hypothetical protein 0.0598 0.0385 0.0492
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.1221 0.1059 0.1567
Schistosoma mansoni serine/threonine protein kinase 0.0375 0.0143 0.035
Loa Loa (eye worm) AUR protein kinase 0.0651 0.0442 0.0566
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0585 0.037 0.037
Schistosoma mansoni serine/threonine protein kinase 0.2911 0.2887 0.7221
Echinococcus granulosus hypothetical protein 0.0943 0.0758 0.112
Echinococcus multilocularis protein kinase 0.0261 0.002 0.002
Trichomonas vaginalis TKL family protein kinase 0.0261 0.002 0.014
Trichomonas vaginalis TKL family protein kinase 0.0261 0.002 0.014
Trichomonas vaginalis TKL family protein kinase 0.0261 0.002 0.014
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0651 0.0442 0.0651
Echinococcus granulosus casein kinase I delta 0.0648 0.0439 0.0647
Echinococcus multilocularis 0.0988 0.0806 0.0806
Trichomonas vaginalis STE family protein kinase 0.1335 0.1181 1
Entamoeba histolytica tyrosine kinase, putative 0.0261 0.002 0.0145
Echinococcus multilocularis slit 2 protein 0.0287 0.0048 0.0048
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0352 0.0118 0.0171
Leishmania major protein kinase A catalytic subunit isoform 1 0.0804 0.0608 0.0897
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0261 0.002 0.002
Schistosoma mansoni tyrosine protein kinase 0.0261 0.002 0.0041
Leishmania major protein kinase A catalytic subunit isoform 2 0.0804 0.0608 0.0897
Schistosoma mansoni serine/threonine protein kinase 0.0261 0.002 0.0041
Echinococcus multilocularis mitogen activated protein kinase 11 0.6472 0.6738 0.6738
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0375 0.0143 0.0207
Brugia malayi Protein kinase domain containing protein 0.1118 0.0947 0.1218
Schistosoma mansoni serine/threonine protein kinase 0.1453 0.1309 0.327
Trichomonas vaginalis TKL family protein kinase 0.0261 0.002 0.014
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0298 0.006 0.0142
Echinococcus multilocularis cyclin dependent kinase 7 0.066 0.0452 0.0452
Schistosoma mansoni tyrosine kinase 0.3937 0.3997 1
Echinococcus multilocularis 0.0943 0.0758 0.0758
Brugia malayi Protein kinase domain containing protein 0.0261 0.002 0.0021
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0576 0.0361 0.0531
Echinococcus granulosus peroxidasin 0.0301 0.0063 0.0089
Schistosoma mansoni cell adhesion molecule 0.08 0.0603 0.1501
Brugia malayi Variant SH3 domain containing protein 0.0393 0.0163 0.0206
Echinococcus multilocularis maternal embryonic leucine zipper kinase 0.0262 0.002 0.002
Brugia malayi Receptor family ligand binding region containing protein 0.0261 0.002 0.0021
Entamoeba histolytica protein kinase, putative 0.0417 0.0189 0.1629
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0436 0.0209 0.0305
Schistosoma mansoni protein kinase 0.0988 0.0806 0.2011
Entamoeba histolytica hypothetical protein 0.0261 0.002 0.0145
Entamoeba histolytica tyrosin kinase, putative 0.0261 0.002 0.0145
Plasmodium falciparum casein kinase 1 0.0648 0.0439 0.4126
Echinococcus granulosus [G-protein-coupledreceptor] kinase 0.1496 0.1356 0.2008
Loa Loa (eye worm) hypothetical protein 0.0301 0.0063 0.0078
Schistosoma mansoni tyrosine kinase 0.0261 0.002 0.0041
Schistosoma mansoni serine/threonine protein kinase 0.0352 0.0119 0.0289
Echinococcus multilocularis lachesin 0.0298 0.006 0.006
Echinococcus granulosus TGF beta receptor type 1 0.0921 0.0734 0.1084
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.1496 0.1356 0.1746
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.1118 0.0947 0.1401
Echinococcus granulosus STE20 serine:threonine protein kinase 0.0663 0.0455 0.0671
Echinococcus granulosus integrin linked protein kinase 0.0261 0.002 0.0024
Echinococcus granulosus serine:threonine protein kinase N2 0.1209 0.1046 0.1548
Entamoeba histolytica protein kinase domain containing protein 0.0261 0.002 0.0145
Trichomonas vaginalis STE family protein kinase 0.0394 0.0164 0.136
Trypanosoma cruzi Protein kinase B 0.0352 0.0118 0.0171
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0895 0.0706 0.0706
Brugia malayi Protein kinase domain containing protein 0.0313 0.0077 0.0095
Echinococcus multilocularis activin receptor type 0.4247 0.4331 0.4331
Trichomonas vaginalis TKL family protein kinase 0.0261 0.002 0.014
Loa Loa (eye worm) hypothetical protein 0.041 0.0181 0.0229
Entamoeba histolytica protein kinase, putative 0.13 0.1144 1
Schistosoma mansoni serine/threonine protein kinase 0.0804 0.0608 0.1513
Echinococcus granulosus cyclin dependent kinase 1 0.0488 0.0266 0.0389
Loa Loa (eye worm) TK/FER protein kinase 0.0491 0.0269 0.0342
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0804 0.0608 0.0897
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0721 0.0517 0.1287
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.6472 0.6738 1
Schistosoma mansoni tyrosine kinase 0.107 0.0895 0.2234
Trichomonas vaginalis AGC family protein kinase 0.0754 0.0553 0.4666
Loa Loa (eye worm) hypothetical protein 0.0964 0.0781 0.1003
Brugia malayi Egg laying defective protein 4 0.0282 0.0043 0.0051
Loa Loa (eye worm) TK/FER protein kinase 0.0491 0.0269 0.0342
Trichomonas vaginalis CMGC family protein kinase 0.0287 0.0048 0.0378
Echinococcus multilocularis protein kinase 0.0261 0.002 0.002
Trichomonas vaginalis CAMK family protein kinase 0.0375 0.0143 0.1185
Entamoeba histolytica protein kinase domain containing protein 0.0413 0.0184 0.1584
Brugia malayi bone morphogenetic protein type 1 receptor 0.1007 0.0827 0.1063
Onchocerca volvulus 0.0721 0.0517 0.0643
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.2513 0.2456 0.3166
Brugia malayi protein kinase C II. 0.0741 0.0539 0.0692
Schistosoma mansoni protein kinase 0.0651 0.0442 0.1098
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0436 0.0209 0.0209
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0335 0.0099 0.0241
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0261 0.002 0.0145
Schistosoma mansoni cell adhesion molecule 0.0298 0.006 0.0142
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0585 0.037 0.0545
Trichomonas vaginalis STE family protein kinase 0.0394 0.0164 0.136
Schistosoma mansoni serine/threonine protein kinase 0.0518 0.0298 0.0737
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0326 0.009 0.0112
Schistosoma mansoni adapter molecule crk 0.041 0.0181 0.0445
Entamoeba histolytica tyrosine kinase, putative 0.0261 0.002 0.0145
Schistosoma mansoni serine/threonine protein kinase 0.0804 0.0608 0.1513
Brugia malayi SH2 domain containing protein 0.0812 0.0616 0.0791
Schistosoma mansoni serine/threonine protein kinase 0.0321 0.0085 0.0205
Entamoeba histolytica cysteine surface protein, putative 0.0261 0.002 0.0145
Onchocerca volvulus 0.0491 0.0269 0.0322
Schistosoma mansoni serine/threonine protein kinase 0.0804 0.0608 0.1513
Trichomonas vaginalis CMGC family protein kinase 0.1221 0.1059 0.8958
Echinococcus granulosus tyrosine protein kinase Fyn 0.1129 0.0959 0.1418
Brugia malayi STE20-like kinase MST 0.0412 0.0183 0.0232
Brugia malayi Tyrosine-protein kinase abl-1 0.1199 0.1035 0.1331
Schistosoma mansoni serine/threonine protein kinase 0.0488 0.0266 0.0657
Schistosoma mansoni serine/threonine protein kinase 0.0354 0.0121 0.0294
Loa Loa (eye worm) hypothetical protein 0.0859 0.0667 0.0857
Schistosoma mansoni tyrosine kinase 0.1456 0.1313 0.3279
Loa Loa (eye worm) TK/FER protein kinase 0.0491 0.0269 0.0342
Entamoeba histolytica protein kinase domain containing protein 0.0261 0.002 0.0145
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0261 0.002 0.0145
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.2338 0.2267 0.2267
Echinococcus multilocularis protein kinase c epsilon type 0.0741 0.0539 0.0539
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.13 0.1144 0.1693
Trichomonas vaginalis CAMK family protein kinase 0.0375 0.0143 0.1185
Echinococcus granulosus dual specificity mitogen activated protein 0.1335 0.1181 0.1749
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.1076 0.0902 0.116
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.6472 0.6738 1
Brugia malayi Protein kinase domain containing protein 0.0491 0.0269 0.0342
Onchocerca volvulus Serine\/threonine kinase homolog 0.0326 0.009 0.0091
Echinococcus multilocularis casein kinase i 0.0648 0.0439 0.0439
Schistosoma mansoni serine/threonine protein kinase 0.066 0.0452 0.1124
Brugia malayi Raf kinase 0.0261 0.002 0.0021
Trichomonas vaginalis AGC family protein kinase 0.0754 0.0553 0.4666
Brugia malayi Protein kinase domain containing protein 0.0261 0.002 0.0021
Entamoeba histolytica protein kinase domain containing protein 0.0287 0.0048 0.039
Echinococcus multilocularis dual specificity 0.0287 0.0048 0.0048
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0462 0.0237 0.0237
Trichomonas vaginalis CMGC family protein kinase 0.1118 0.0947 0.8006
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0474 0.025 0.0366
Trichomonas vaginalis TKL family protein kinase 0.0261 0.002 0.014
Loa Loa (eye worm) AGC/NDR protein kinase 0.0576 0.0361 0.0462
Trichomonas vaginalis conserved hypothetical protein 0.0261 0.002 0.014
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0949 0.0764 0.0764
Trichomonas vaginalis TKL family protein kinase 0.0261 0.002 0.014
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0261 0.002 0.002
Giardia lamblia Kinase, PLK 0.0326 0.009 0.0734
Trichomonas vaginalis TKL family protein kinase 0.0261 0.002 0.014
Schistosoma mansoni tyrosine kinase 0.0261 0.002 0.0041
Loa Loa (eye worm) hypothetical protein 0.1534 0.1397 0.1799
Plasmodium falciparum protein kinase 5 0.0488 0.0266 0.2485
Echinococcus multilocularis serine:threonine protein kinase 3 0.0412 0.0183 0.0183
Loa Loa (eye worm) TK protein kinase 0.0261 0.002 0.0021
Loa Loa (eye worm) SRC-1 0.1129 0.0959 0.1233
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.2911 0.2887 0.3722
Trichomonas vaginalis CAMK family protein kinase 0.0375 0.0143 0.1185
Onchocerca volvulus Basement membrane proteoglycan homolog 0.0298 0.006 0.0052
Plasmodium vivax serine/threonine kinase-1, putative 0.1118 0.0947 0.8937
Plasmodium falciparum calcium-dependent protein kinase 2 0.0585 0.037 0.3478
Entamoeba histolytica receptor protein kinase, putative 0.0261 0.002 0.0145
Echinococcus multilocularis casein kinase I delta 0.0648 0.0439 0.0439
Plasmodium falciparum protein kinase, putative 0.0261 0.002 0.0156
Loa Loa (eye worm) AUR protein kinase 0.0651 0.0442 0.0566
Entamoeba histolytica protein kinase, putative 0.0371 0.0139 0.1187
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.1453 0.1309 0.1939
Echinococcus granulosus retinal guanylyl cyclase 2 0.0261 0.002 0.0024
Echinococcus granulosus casein kinase I gamma 0.0366 0.0133 0.0192
Loa Loa (eye worm) hypothetical protein 0.0261 0.002 0.0021
Loa Loa (eye worm) hypothetical protein 0.0353 0.012 0.015
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0306 0.0068 0.0096
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0804 0.0608 0.0608
Echinococcus multilocularis integrin linked protein kinase 0.0261 0.002 0.002
Brugia malayi casein kinase I 0.0648 0.0439 0.0562
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0261 0.002 0.0021
Loa Loa (eye worm) protein kinase domain-containing protein 0.0366 0.0133 0.0167
Echinococcus granulosus dual specificity 0.0287 0.0048 0.0066
Echinococcus multilocularis tyrosine protein kinase Abl 0.1413 0.1266 0.1266
Echinococcus granulosus leucine rich repeat serine:threonine protein 0.0479 0.0256 0.0375
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0261 0.002 0.002
Schistosoma mansoni tyrosine kinase 0.0559 0.0342 0.0849
Leishmania major protein kinase, putative 0.0436 0.0209 0.0305
Loa Loa (eye worm) hypothetical protein 0.4623 0.4738 0.6112
Brugia malayi Protein kinase domain containing protein 0.0261 0.002 0.0021
Echinococcus granulosus serine:threonine protein kinase 0.0346 0.0112 0.0161
Loa Loa (eye worm) AGC/PKA protein kinase 0.0804 0.0608 0.078
Echinococcus multilocularis tyrosine protein kinase csk 0.0261 0.002 0.002
Toxoplasma gondii casein kinase I 0.0648 0.0439 0.4126
Echinococcus multilocularis cyclin dependent kinase 1 0.0488 0.0266 0.0266
Echinococcus granulosus dual specificity 0.13 0.1144 0.1693
Echinococcus granulosus contactin 0.0335 0.0099 0.0143
Schistosoma mansoni protein kinase 0.0261 0.002 0.0041
Trichomonas vaginalis CAMK family protein kinase 0.0585 0.037 0.3115
Brugia malayi ribosomal protein S6 kinase alpha 3 0.1051 0.0874 0.1124
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0462 0.0237 0.0347
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0666 0.0458 0.1139
Entamoeba histolytica protein kinase domain containing protein 0.0261 0.002 0.0145
Loa Loa (eye worm) CMGC/GSK protein kinase 0.1221 0.1059 0.1362
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0282 0.0043 0.0043
Brugia malayi Protein kinase domain containing protein 0.0491 0.0269 0.0342
Echinococcus multilocularis neuroglian 0.0867 0.0675 0.0675
Loa Loa (eye worm) IKK protein kinase 0.7408 0.775 1
Echinococcus multilocularis casein kinase I alpha 0.0648 0.0439 0.0439
Echinococcus granulosus serine:threonine protein kinase 3 0.0412 0.0183 0.0267
Schistosoma mansoni rap gtpase-activating protein 0.0721 0.0517 0.1287
Echinococcus granulosus protein kinase c epsilon type 0.0741 0.0539 0.0796
Plasmodium falciparum calcium-dependent protein kinase 5 0.0585 0.037 0.3478
Loa Loa (eye worm) hypothetical protein 0.0261 0.002 0.0021
Echinococcus granulosus tyrosine protein kinase Lyn 0.1303 0.1147 0.1699
Trypanosoma brucei protein kinase, putative 0.027 0.003 0.0039
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0585 0.037 0.0545
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0775 0.0576 0.0739
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.0557 0.034 0.0435
Brugia malayi serine/threonine-protein kinase PAK 7 0.2293 0.2217 0.2858
Trichomonas vaginalis TK family protein kinase 0.0261 0.002 0.014
Trichomonas vaginalis AGC family protein kinase 0.0576 0.0361 0.3035
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0436 0.0209 0.0305
Loa Loa (eye worm) hypothetical protein 0.0943 0.0758 0.0974
Plasmodium vivax tyrosine kinase-like protein, putative 0.0261 0.002 0.0156
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.6472 0.6738 0.8694
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0326 0.009 0.009
Schistosoma mansoni serine/threonine-protein kinase 0.0352 0.0118 0.0288
Onchocerca volvulus 0.0491 0.0269 0.0322
Schistosoma mansoni growth factor receptor-bound protein 0.041 0.0181 0.0445
Echinococcus multilocularis receptor type guanylyl cyclase 0.0261 0.002 0.002
Entamoeba histolytica tyrosine kinase, putative 0.0261 0.002 0.0145
Loa Loa (eye worm) TK/FAK protein kinase 0.3981 0.4044 0.5216
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0804 0.0608 0.0897
Brugia malayi Immunoglobulin I-set domain containing protein 0.0298 0.006 0.0073
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.1118 0.0947 0.8937
Entamoeba histolytica protein kinase , putative 0.0651 0.0442 0.3846
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0804 0.0608 0.0897
Schistosoma mansoni serine/threonine protein kinase 0.0413 0.0184 0.0452
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.111 0.0938 0.1388
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0804 0.0608 0.0897
Loa Loa (eye worm) CMGC/GSK protein kinase 0.1221 0.1059 0.1362
Schistosoma mansoni protein kinase 0.0261 0.002 0.0041
Schistosoma mansoni tyrosine kinase 0.0261 0.002 0.0041
Echinococcus granulosus tyrosine protein kinase Fyn 0.1129 0.0959 0.1418
Loa Loa (eye worm) hypothetical protein 0.0602 0.0389 0.0498
Echinococcus granulosus roundabout 2 0.0335 0.0099 0.0143
Entamoeba histolytica hypothetical protein 0.0403 0.0173 0.1488
Entamoeba histolytica protein kinase domain containing protein 0.0261 0.002 0.0145
Trichomonas vaginalis TKL family protein kinase 0.0261 0.002 0.014
Schistosoma mansoni kinase 0.0395 0.0164 0.0404
Schistosoma mansoni tyrosine kinase 0.0261 0.002 0.0041
Entamoeba histolytica p21-activated kinase 0.044 0.0214 0.1847
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0412 0.0183 0.0232
Schistosoma mansoni protein kinase C mu 0.1126 0.0955 0.2384
Toxoplasma gondii histone kinase SNF1, putative 0.0375 0.0143 0.1323
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0705 0.05 0.05
Brugia malayi Protein kinase domain containing protein 0.0261 0.002 0.0021
Loa Loa (eye worm) hypothetical protein 0.0998 0.0817 0.105
Echinococcus granulosus raf serine:threonine protein kinase 0.0424 0.0197 0.0287
Brugia malayi Protein kinase domain containing protein 0.0344 0.011 0.0137
Schistosoma mansoni serine/threonine protein kinase 0.0488 0.0266 0.0657
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0298 0.006 0.0073
Echinococcus granulosus natriuretic peptide receptor 1 0.0261 0.002 0.0024
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.1496 0.1356 0.1746
Trichomonas vaginalis CAMK family protein kinase 0.0375 0.0143 0.1185
Brugia malayi Protein kinase domain containing protein 0.0261 0.002 0.0021
Loa Loa (eye worm) TK protein kinase 0.0582 0.0367 0.047
Brugia malayi Protein kinase domain containing protein 0.0863 0.0671 0.0862
Schistosoma mansoni tyrosine kinase 0.0717 0.0513 0.1277
Trichomonas vaginalis CMGC family protein kinase 0.0287 0.0048 0.0378
Brugia malayi Protein kinase domain containing protein 0.2513 0.2456 0.3166
Echinococcus granulosus epidermal growth factor receptor 0.0923 0.0736 0.1088
Plasmodium falciparum cGMP-dependent protein kinase 0.0282 0.0043 0.0374
Brugia malayi Protein kinase c protein 2 0.0381 0.015 0.0189
Echinococcus granulosus protein kinase 0.0988 0.0806 0.1193
Loa Loa (eye worm) AUR protein kinase 0.0651 0.0442 0.0566
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0326 0.009 0.0128
Schistosoma mansoni serine/threonine protein kinase 0.0786 0.0588 0.1463
Schistosoma mansoni tyrosine kinase 0.0671 0.0463 0.1152
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0804 0.0608 0.0897
Brugia malayi Immunoglobulin I-set domain containing protein 0.0488 0.0266 0.0339
Toxoplasma gondii protein kinase domain-containing protein 0.0261 0.002 0.0156
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0261 0.002 0.0156
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0666 0.0458 0.1139
Schistosoma mansoni serine/threonine kinase 0.0576 0.0361 0.0896
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0804 0.0608 0.0608
Brugia malayi Protein kinase domain containing protein 0.0491 0.0269 0.0342
Schistosoma mansoni serine/threonine protein kinase 0.0375 0.0144 0.0351
Echinococcus multilocularis c Jun NH2 terminal kinase 0.3061 0.3049 0.3049
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0261 0.002 0.0145
Onchocerca volvulus 0.0491 0.0269 0.0322
Trichomonas vaginalis TKL family protein kinase 0.0261 0.002 0.014
Trypanosoma cruzi protein kinase, putative 0.0261 0.002 0.0024
Brugia malayi Variant SH3 domain containing protein 0.041 0.0181 0.0229
Loa Loa (eye worm) TK/FER protein kinase 0.0261 0.002 0.0021
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0949 0.0764 0.1129
Echinococcus granulosus MAP kinase activated protein kinase 2 0.0557 0.034 0.05
Toxoplasma gondii AGC kinase 0.0804 0.0608 0.5725
Trichomonas vaginalis TKL family protein kinase 0.0261 0.002 0.014
Echinococcus multilocularis calcium dependent protein kinase 0.041 0.0182 0.0182
Echinococcus granulosus growth factor receptor bound protein 2 0.0427 0.0199 0.0291
Entamoeba histolytica leucine-rich repeat domain-containing protein 0.0264 0.0023 0.0175
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0432 0.0205 0.026
Trichomonas vaginalis TKL family protein kinase 0.0263 0.0022 0.0163
Brugia malayi cyclin-dependent kinase 9 0.0413 0.0184 0.0233
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0261 0.002 0.0145
Loa Loa (eye worm) hypothetical protein 0.0261 0.002 0.0021
Entamoeba histolytica protein kinase, putative 0.0585 0.037 0.3218
Brugia malayi C-terminal src kinase protein 1 0.0261 0.002 0.0021
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0491 0.0269 0.2326
Entamoeba histolytica protein kinase, putative 0.0261 0.002 0.0145
Schistosoma mansoni tyrosine kinase 0.0487 0.0264 0.0654
Schistosoma mansoni tyrosine kinase 0.0261 0.002 0.0041
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0804 0.0608 0.0897
Brugia malayi Immunoglobulin I-set domain containing protein 0.0298 0.006 0.0073
Plasmodium vivax glycogen synthase kinase 3, putative 0.1221 0.1059 1
Trichomonas vaginalis CAMK family protein kinase 0.0375 0.0143 0.1185
Entamoeba histolytica protein kinase, putative 0.0261 0.002 0.0145
Echinococcus multilocularis tyrosine protein kinase Src42A 0.1129 0.0959 0.0959
Entamoeba histolytica protein kinase domain containing protein 0.0261 0.002 0.0145
Giardia lamblia Protein 21.1 0.0261 0.002 0.014
Echinococcus granulosus aurora kinase A 0.0651 0.0442 0.0651
Echinococcus granulosus receptor type guanylyl cyclase 0.0261 0.002 0.0024
Brugia malayi Protein kinase domain containing protein 0.0261 0.002 0.0021
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0488 0.0266 0.2485
Echinococcus multilocularis dual specificity 0.0287 0.0048 0.0048
Loa Loa (eye worm) TK/FER protein kinase 0.0261 0.002 0.0021
Loa Loa (eye worm) TK/FER protein kinase 0.0812 0.0616 0.0791
Toxoplasma gondii STE kinase 0.0261 0.002 0.0156
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0261 0.002 0.002
Echinococcus granulosus casein kinase i 0.0648 0.0439 0.0647
Entamoeba histolytica protein kinase domain containing protein 0.0261 0.002 0.0145
Brugia malayi Protein kinase domain containing protein 0.0491 0.0269 0.0342
Brugia malayi Protein kinase domain containing protein 0.0754 0.0553 0.071
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.0557 0.034 0.034
Loa Loa (eye worm) TK protein kinase 0.0261 0.002 0.0021
Entamoeba histolytica protein kinase, putative 0.0261 0.002 0.0145
Echinococcus granulosus twitchin 0.1042 0.0864 0.1278
Trichomonas vaginalis TKL family protein kinase 0.0261 0.002 0.014
Giardia lamblia Kinase 0.0261 0.002 0.014
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.0375 0.0143 0.0207
Entamoeba histolytica protein kinase, putative 0.0719 0.0515 0.4487
Schistosoma mansoni serine/threonine protein kinase 0.0557 0.034 0.0844
Schistosoma mansoni roundabout 0.0298 0.006 0.0142
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0895 0.0706 0.1043
Onchocerca volvulus 0.0786 0.0588 0.0735
Echinococcus granulosus tyrosine protein kinase pr2 0.0261 0.002 0.0024
Loa Loa (eye worm) G protein-coupled receptor kinase 1 0.1496 0.1356 0.1746
Trichomonas vaginalis TKL family protein kinase 0.0261 0.002 0.014
Schistosoma mansoni serine/threonine protein kinase 0.0424 0.0197 0.0484
Trypanosoma brucei polo-like protein kinase 0.0326 0.009 0.0128
Brugia malayi serine/threonine protein kinase 6 0.0651 0.0442 0.0566
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0859 0.0667 0.0985
Giardia lamblia Kinase, STE STE20 0.0394 0.0164 0.136
Echinococcus granulosus Protein kinase C brain isozyme 0.0783 0.0585 0.0863
Trichomonas vaginalis CK1 family protein kinase 0.0648 0.0439 0.3696
Loa Loa (eye worm) RGC/RGC protein kinase 0.0261 0.002 0.0021
Schistosoma mansoni tyrosine kinase 0.0923 0.0736 0.1836
Trichomonas vaginalis TKL family protein kinase 0.0261 0.002 0.014
Entamoeba histolytica protein kinase domain containing protein 0.0261 0.002 0.0145
Schistosoma mansoni tyrosine kinase 0.0662 0.0454 0.1129
Brugia malayi Tyrosine-protein kinase PR2 0.0261 0.002 0.0021
Schistosoma mansoni protein kinase 0.0261 0.002 0.0041
Brugia malayi Protein kinase domain containing protein 0.0261 0.002 0.0021
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0576 0.0361 0.0462
Echinococcus multilocularis protein tyrosine kinase 0.3937 0.3997 0.3997
Loa Loa (eye worm) TK protein kinase 0.1702 0.1579 0.2034
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.2551 0.2497 0.3702
Loa Loa (eye worm) RGC/RGC protein kinase 0.0261 0.002 0.0021
Echinococcus granulosus atrial natriuretic peptide receptor 1 0.0261 0.002 0.0024
Echinococcus multilocularis cyclin dependent kinase 0.0488 0.0266 0.0266
Echinococcus multilocularis twitchin 0.0375 0.0144 0.0144
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.0287 0.0048 0.0422
Trypanosoma brucei AGC/RSK family serine/threonine kinase, putative 0.0261 0.002 0.0024
Echinococcus granulosus protein kinase 0.0261 0.002 0.0024
Trypanosoma brucei SNF1-related protein kinases, putative 0.0375 0.0143 0.0207
Schistosoma mansoni serine/threonine protein kinase 0.0783 0.0585 0.1456
Loa Loa (eye worm) hypothetical protein 0.0261 0.002 0.0021
Echinococcus granulosus TGF-beta receptor type-1 0.0921 0.0734 0.1084
Loa Loa (eye worm) TK/CSK protein kinase 0.0261 0.002 0.0021
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0585 0.037 0.3478
Onchocerca volvulus 0.0491 0.0269 0.0322
Echinococcus multilocularis tyrosine protein kinase 0.0261 0.002 0.002
Echinococcus multilocularis Immunoglobulin 0.0666 0.0458 0.0458
Echinococcus granulosus tyrosine kinase 0.0949 0.0764 0.1129
Schistosoma mansoni serine/threonine RGC 0.0261 0.002 0.0041
Schistosoma mansoni tyrosine kinase 0.1502 0.1362 0.3402
Echinococcus granulosus casein kinase I delta 0.0648 0.0439 0.0647
Leishmania major protein kinase, putative 0.0261 0.002 0.0024
Schistosoma mansoni serine/threonine-protein kinase 0.0352 0.0118 0.0288
Schistosoma mansoni serine/threonine protein kinase 0.0645 0.0435 0.1081
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0375 0.0143 0.0207
Trypanosoma brucei mitogen-activated protein kinase kinase 5 0.1335 0.1181 0.1749
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0741 0.0539 0.0692
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0394 0.0164 0.0164
Trichomonas vaginalis TKL family protein kinase 0.0261 0.002 0.014
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.5735 0.5941 0.8816
Trichomonas vaginalis TKL family protein kinase 0.0261 0.002 0.014
Echinococcus granulosus tyrosine protein kinase 0.0261 0.002 0.0024
Schistosoma mansoni serine/threonine protein kinase 0.111 0.0938 0.2341
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0278 0.0038 0.0045
Echinococcus multilocularis cyclin dependent kinase 9 0.0454 0.0229 0.0229
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0393 0.0163 0.04
Schistosoma mansoni serine/threonine protein kinase 0.0412 0.0183 0.045
Brugia malayi Protein kinase domain containing protein 0.0346 0.0112 0.014
Echinococcus granulosus Vam6:Vps39 protein 0.0721 0.0517 0.0763
Entamoeba histolytica protein kinase, putative 0.0417 0.0189 0.1629
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0651 0.0442 0.4156
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0261 0.002 0.0021
Entamoeba histolytica tyrosine kinase, putative 0.0261 0.002 0.0145
Schistosoma mansoni hypothetical protein 0.0353 0.012 0.0291
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.1966 0.1864 0.2402
Trichomonas vaginalis TKL family protein kinase 0.0261 0.002 0.014
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.2513 0.2456 0.3642
Brugia malayi Protein kinase domain containing protein 0.0261 0.002 0.0021
Trichomonas vaginalis CAMK family protein kinase 0.0375 0.0143 0.1185
Trichomonas vaginalis TKL family protein kinase 0.0261 0.002 0.014
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.0261 0.002 0.0021
Loa Loa (eye worm) AGC/PKN protein kinase 0.1786 0.1669 0.215
Echinococcus multilocularis mitogen activated protein kinase 14 0.6472 0.6738 0.6738
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.1118 0.0947 0.1401
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0488 0.0266 0.0339
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.1643 0.1515 0.1951
Echinococcus granulosus lachesin 0.0298 0.006 0.0084
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.1118 0.0947 0.1401
Echinococcus granulosus tyrosine protein kinase csk 0.0261 0.002 0.0024
Loa Loa (eye worm) TK/ABL protein kinase 0.2432 0.2369 0.3053
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0576 0.0361 0.0361
Toxoplasma gondii AGC kinase 0.0804 0.0608 0.5725
Entamoeba histolytica tyrosine kinase, putative 0.0261 0.002 0.0145
Entamoeba histolytica protein kinase, putative 0.0651 0.0442 0.3846
Trichomonas vaginalis CAMK family protein kinase 0.0326 0.009 0.0734
Loa Loa (eye worm) TK/Met protein kinase 0.0261 0.002 0.0021
Schistosoma mansoni nck2/grb4 0.041 0.0181 0.0445
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.13 0.1144 0.1693
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0393 0.0163 0.0206
Trichomonas vaginalis TKL family protein kinase 0.0261 0.002 0.014
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.1098 0.0925 0.1368
Brugia malayi Protein kinase domain containing protein 0.5239 0.5404 0.6972
Brugia malayi Peroxidasin 0.0301 0.0063 0.0078
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.1966 0.1864 0.2402
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0585 0.037 0.3478
Trichomonas vaginalis TKL family protein kinase 0.0261 0.002 0.014
Loa Loa (eye worm) CAMK protein kinase 0.0412 0.0183 0.0232
Trichomonas vaginalis br serine/threonine-protein kinase, putative 0.0261 0.002 0.014
Loa Loa (eye worm) gastrulation defective protein 1 0.1638 0.151 0.1944
Schistosoma mansoni tyrosine kinase 0.0261 0.002 0.0041
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0812 0.0616 0.0616
Loa Loa (eye worm) TK protein kinase 0.0261 0.002 0.0021
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.0346 0.0112 0.014
Schistosoma mansoni serine/threonine protein kinase 0.0347 0.0113 0.0274
Schistosoma mansoni serine/threonine protein kinase 0.0347 0.0113 0.0274
Loa Loa (eye worm) hypothetical protein 0.1043 0.0865 0.1113
Entamoeba histolytica protein kinase, putative 0.0586 0.0372 0.3231
Trichomonas vaginalis AGC family protein kinase 0.0754 0.0553 0.4666
Entamoeba histolytica casein kinase 1, putative 0.0648 0.0439 0.3818
Echinococcus granulosus mitogen activated protein kinase 11 0.6472 0.6738 1
Loa Loa (eye worm) sex muscle abnormal protein 5 0.041 0.0181 0.0229
Brugia malayi Protein kinase domain containing protein 0.0261 0.002 0.0021
Loa Loa (eye worm) hypothetical protein 0.0491 0.0269 0.0342
Entamoeba histolytica protein kinase domain containing protein 0.13 0.1144 1
Trichomonas vaginalis TKL family protein kinase 0.0261 0.002 0.014
Schistosoma mansoni serine/threonine protein kinase 0.2338 0.2267 0.5668
Brugia malayi Protein kinase domain containing protein 0.0615 0.0403 0.0515
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.041 0.0181 0.0445
Schistosoma mansoni serine/threonine protein kinase 0.0637 0.0427 0.1061
Trichomonas vaginalis CAMK family protein kinase 0.0375 0.0143 0.1185
Echinococcus multilocularis roundabout 2 0.0335 0.0099 0.0099
Echinococcus granulosus tyrosine protein kinase ABL1 0.2432 0.2369 0.3512
Schistosoma mansoni protein kinase 0.0436 0.0209 0.0514
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0576 0.0361 0.0361
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0648 0.0439 0.0562
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.2293 0.2217 0.2858
Giardia lamblia Aurora kinase 0.0651 0.0442 0.3723
Entamoeba histolytica protein kinase, putative 0.0264 0.0023 0.0175
Onchocerca volvulus 0.2687 0.2644 0.3395
Echinococcus granulosus insulin growth factor 1 receptor beta 0.1493 0.1352 0.2003
Schistosoma mansoni tyrosine kinase 0.0261 0.002 0.0041
Trichomonas vaginalis AGC family protein kinase 0.0618 0.0406 0.3419
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0648 0.0439 0.0562
Echinococcus multilocularis neuroglian 0.0335 0.0099 0.0099
Entamoeba histolytica serine/threonine kinase, putative 0.0261 0.002 0.0145
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0518 0.0298 0.0298
Schistosoma mansoni serine/threonine protein kinase 0.0282 0.0043 0.0099
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0651 0.0442 0.3846
Loa Loa (eye worm) hypothetical protein 0.0375 0.0143 0.018
Trichomonas vaginalis CAMK family protein kinase 0.0261 0.002 0.014
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0775 0.0576 0.0739
Schistosoma mansoni kinase 0.0413 0.0184 0.0452
Giardia lamblia Kinase, CMGC GSK 0.1221 0.1059 0.8958
Echinococcus multilocularis tyrosine protein kinase otk 0.0298 0.006 0.006
Trichomonas vaginalis conserved hypothetical protein 0.0261 0.002 0.014
Brugia malayi Immunoglobulin I-set domain containing protein 0.0298 0.006 0.0073
Schistosoma mansoni protein kinase 0.0436 0.0209 0.0514
Giardia lamblia Kinase, CMGC DYRK 0.0287 0.0048 0.0378
Brugia malayi Protein kinase domain containing protein 0.1815 0.1701 0.2191
Trichomonas vaginalis protein kinase atn1, putative 0.0261 0.002 0.014
Entamoeba histolytica protein kinase, putative 0.0261 0.002 0.0145
Brugia malayi protein kinase C3,putative 0.0426 0.0198 0.0251
Entamoeba histolytica protein kinase domain containing protein 0.0261 0.002 0.0145
Entamoeba histolytica hypothetical protein 0.0261 0.002 0.0145
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0585 0.037 0.3478
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.2911 0.2887 0.2887
Schistosoma mansoni serine/threonine protein kinase 0.0287 0.0048 0.0112
Entamoeba histolytica protein kinase, putative 0.0405 0.0175 0.1506
Entamoeba histolytica protein kinase, putative 0.0261 0.002 0.0145
Brugia malayi Protein kinase domain containing protein 0.0261 0.002 0.0021
Loa Loa (eye worm) hypothetical protein 0.1815 0.1701 0.2191
Trichomonas vaginalis serine-threonine protein kinase, putative 0.0261 0.002 0.014
Brugia malayi Protein kinase domain containing protein 0.0775 0.0576 0.0739
Giardia lamblia Kinase, AGC AKT 0.1051 0.0874 0.7393
Trichomonas vaginalis AGC family protein kinase 0.0576 0.0361 0.3035
Echinococcus granulosus neuroglian 0.0867 0.0675 0.0998
Loa Loa (eye worm) hypothetical protein 0.1456 0.1312 0.1689
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0671 0.0463 0.1152
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0585 0.037 0.0474
Loa Loa (eye worm) hypothetical protein 0.0598 0.0385 0.0492
Echinococcus granulosus defective proboscis extension response 0.0666 0.0458 0.0675
Schistosoma mansoni protein kinase 0.0261 0.002 0.0041
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0326 0.009 0.0128
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0721 0.0517 0.1287
Brugia malayi Protein kinase domain containing protein 0.0261 0.002 0.0021
Trichomonas vaginalis TKL family protein kinase 0.0261 0.002 0.014
Echinococcus multilocularis beta adrenergic receptor kinase 0.0321 0.0085 0.0085
Loa Loa (eye worm) hypothetical protein 0.0261 0.002 0.0021
Trichomonas vaginalis AGC family protein kinase 0.0651 0.0442 0.3723
Trichomonas vaginalis TKL family protein kinase 0.0261 0.002 0.014
Echinococcus multilocularis tyrosine protein kinase Src64B 0.1129 0.0959 0.0959
Schistosoma mansoni protein kinase 0.0261 0.002 0.0041
Schistosoma mansoni serine/threonine protein kinase 0.13 0.1144 0.2856
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0261 0.002 0.0041
Trichomonas vaginalis CAMK family protein kinase 0.0375 0.0143 0.1185
Loa Loa (eye worm) hypothetical protein 0.0261 0.002 0.0021
Trichomonas vaginalis CAMK family protein kinase 0.0326 0.009 0.0734
Brugia malayi serine/threonine kinase 12 0.0651 0.0442 0.0566
Schistosoma mansoni hypothetical protein 0.0261 0.002 0.0041
Echinococcus multilocularis PAK box P21 Rho binding 0.0371 0.0139 0.0139
Entamoeba histolytica protein kinase, putative 0.0576 0.0361 0.3136
Echinococcus granulosus cGMP dependent protein kinase 1 0.0282 0.0043 0.0059
Echinococcus multilocularis TGF beta receptor type 1 0.0921 0.0734 0.0734
Echinococcus multilocularis growth factor receptor bound protein 2 0.041 0.0181 0.0181
Trypanosoma cruzi mitogen-activated protein kinase kinase 5 0.1335 0.1181 0.1749
Echinococcus granulosus retinal guanylyl cyclase 2 0.0261 0.002 0.0024
Entamoeba histolytica protein kinase domain containing protein 0.1221 0.1059 0.9255
Plasmodium falciparum serine/threonine protein kinase KIN 0.0375 0.0143 0.1323
Schistosoma mansoni protein kinase 0.0921 0.0734 0.1829
Entamoeba histolytica protein kinase domain containing protein 0.0261 0.002 0.0145
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0261 0.002 0.014
Giardia lamblia Kinase, NEK 0.0261 0.002 0.014
Trichomonas vaginalis AGC family protein kinase 0.0651 0.0442 0.3723
Entamoeba histolytica protein kinase domain containing protein 0.0261 0.002 0.0145
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0518 0.0298 0.0298
Entamoeba histolytica protein kinase, putative 0.0261 0.002 0.0145
Entamoeba histolytica protein kinase, putative 0.0261 0.002 0.0145
Echinococcus multilocularis tyrosine kinase 0.0491 0.0269 0.0269
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0488 0.0266 0.0389
Echinococcus granulosus maternal embryonic leucine zipper kinase 0.0262 0.002 0.0025
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0261 0.002 0.0021
Entamoeba histolytica protein kinase, putative 0.13 0.1144 1
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0306 0.0068 0.0614
Entamoeba histolytica serine/threonine kinase, putative 0.0261 0.002 0.0145
Schistosoma mansoni src-type protein tyrosine kinase-related 0.0261 0.002 0.0041
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0261 0.002 0.0145
Echinococcus granulosus protein tyrosine kinase 0.3937 0.3997 0.5929
Giardia lamblia Kinase, NEK 0.0284 0.0045 0.035
Trichomonas vaginalis TKL family protein kinase 0.0261 0.002 0.014
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.2513 0.2456 0.2456
Brugia malayi map kinase activated protein kinase protein 2 0.0557 0.034 0.0435
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0268 0.0027 0.0031
Giardia lamblia Kinase, NEK 0.0284 0.0045 0.035
Trichomonas vaginalis conserved hypothetical protein 0.0261 0.002 0.014
Trypanosoma brucei rac serine-threonine kinase, putative 0.0754 0.0553 0.0816
Schistosoma mansoni tyrosine kinase 0.0662 0.0454 0.1129
Trichomonas vaginalis TKL family protein kinase 0.0261 0.002 0.014
Onchocerca volvulus 0.0951 0.0766 0.0966
Brugia malayi Protein kinase domain containing protein 0.0775 0.0576 0.0739
Entamoeba histolytica hypothetical protein 0.13 0.1144 1
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0585 0.037 0.0474
Loa Loa (eye worm) hypothetical protein 0.0666 0.0458 0.0587
Schistosoma mansoni protein kinase 0.0648 0.0439 0.109
Loa Loa (eye worm) hypothetical protein 0.0669 0.0462 0.0592
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0405 0.0175 0.1506
Entamoeba histolytica tyrosin kinase, putative 0.0261 0.002 0.0145
Echinococcus granulosus rho-associated protein kinase 1 0.0786 0.0588 0.0868
Brugia malayi Immunoglobulin I-set domain containing protein 0.0298 0.006 0.0073
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0293 0.0055 0.0055
Entamoeba histolytica tyrosine kinase, putative 0.0261 0.002 0.0145
Schistosoma mansoni protein kinase 0.0394 0.0164 0.0401
Brugia malayi Protein kinase domain containing protein 0.1456 0.1313 0.169
Trichomonas vaginalis STE family protein kinase 0.0371 0.0139 0.1149
Schistosoma mansoni tyrosine kinase 0.0261 0.002 0.0041
Schistosoma mansoni nephrin 0.0904 0.0715 0.1782
Echinococcus multilocularis dual specificity 0.0287 0.0048 0.0048
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0394 0.0164 0.0238
Trichomonas vaginalis CMGC family protein kinase 0.0488 0.0266 0.2226
Echinococcus granulosus tyrosine protein kinase Fyn 0.1129 0.0959 0.1418
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0648 0.0439 0.0647
Trypanosoma cruzi polo-like protein kinase, putative 0.0326 0.009 0.0128
Trichomonas vaginalis TKL family protein kinase 0.0261 0.002 0.014
Schistosoma mansoni ephrin receptor 0.0329 0.0093 0.0225
Plasmodium falciparum protein kinase, putative 0.0261 0.002 0.0156
Trypanosoma brucei cdc2-related kinase 3 0.0488 0.0266 0.0389
Entamoeba histolytica serine/threonine kinase, putative 0.0261 0.002 0.0145
Loa Loa (eye worm) TK/FER protein kinase 0.0261 0.002 0.0021
Trichomonas vaginalis AGC family protein kinase 0.0268 0.0027 0.0202
Trichomonas vaginalis CAMK family protein kinase 0.0375 0.0143 0.1185
Echinococcus granulosus protein kinase c iota type 0.0828 0.0633 0.0934
Loa Loa (eye worm) TK/ROR protein kinase 0.0462 0.0237 0.0302
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0488 0.0266 0.0339
Schistosoma mansoni serine/threonine protein kinase 0.0585 0.037 0.0919
Schistosoma mansoni atypical protein kinase C 0.0834 0.064 0.1594
Loa Loa (eye worm) hypothetical protein 0.0353 0.012 0.015
Trichomonas vaginalis AGC family protein kinase 0.0651 0.0442 0.3723
Echinococcus multilocularis epidermal growth factor receptor 0.0923 0.0736 0.0736
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0764 0.0564 0.0724
Schistosoma mansoni protein kinase 0.0394 0.0164 0.0401
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.6472 0.6738 1
Giardia lamblia Kinase, CMGC CDK 0.0488 0.0266 0.2226
Trypanosoma cruzi cdc2-related kinase 3 0.0488 0.0266 0.0389
Plasmodium falciparum tyrosine kinase-like protein 0.0261 0.002 0.0156
Entamoeba histolytica protein kinase, putative 0.0261 0.002 0.0145
Trichomonas vaginalis STE family protein kinase 0.0394 0.0164 0.136
Echinococcus multilocularis tyrosine protein kinase csk 0.0261 0.002 0.002
Entamoeba histolytica protein kinase, putative 0.0261 0.002 0.0145
Entamoeba histolytica protein kinase domain containing protein 0.0261 0.002 0.0145
Echinococcus multilocularis serine threonine protein kinase 0.062 0.0408 0.0408
Leishmania major protein kinase A catalytic subunit 0.0804 0.0608 0.0897
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0402 0.0172 0.1433
Entamoeba histolytica protein kinase, putative 0.0261 0.002 0.0145
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0721 0.0517 0.0763
Echinococcus granulosus calcium activated potassium channel 0.0347 0.0113 0.0162
Brugia malayi proto-oncogene tyrosine-protein kinase FER 0.0261 0.002 0.0021
Trichomonas vaginalis TKL family protein kinase 0.0261 0.002 0.014
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0261 0.002 0.0145
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0261 0.002 0.0145
Entamoeba histolytica ankyrin repeat protein 0.0261 0.002 0.0145
Loa Loa (eye worm) hypothetical protein 0.0666 0.0458 0.0587
Echinococcus granulosus dual specificity 0.0287 0.0048 0.0066
Schistosoma mansoni tyrosine kinase 0.0261 0.002 0.0041
Trichomonas vaginalis TKL family protein kinase 0.0261 0.002 0.014
Trichomonas vaginalis CAMK family protein kinase 0.0434 0.0207 0.1726
Brugia malayi Protein kinase domain containing protein 0.2338 0.2267 0.2922
Echinococcus multilocularis serine:threonine protein kinase 0.0346 0.0112 0.0112
Trichomonas vaginalis CAMK family protein kinase 0.0326 0.009 0.0734
Echinococcus multilocularis protein KINase family member (kin 25) 0.0859 0.0667 0.0667
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.0287 0.0048 0.0057
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.0434 0.0207 0.0262
Echinococcus multilocularis tyrosine protein kinase Fgr 0.1129 0.0959 0.0959
Trichomonas vaginalis TKL family protein kinase 0.0261 0.002 0.014
Echinococcus granulosus dual specificity protein kinase clk2 0.1118 0.0947 0.1401
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0261 0.002 0.0041
Loa Loa (eye worm) TK/INSR protein kinase 0.1456 0.1313 0.169
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0282 0.0043 0.0043
Trichomonas vaginalis CK1 family protein kinase 0.0648 0.0439 0.3696
Schistosoma mansoni serine/threonine protein kinase 0.0741 0.0539 0.1342
Onchocerca volvulus 0.0788 0.059 0.0737
Brugia malayi Variant SH3 domain containing protein 0.0278 0.0038 0.0045
Entamoeba histolytica tyrosine kinase, putative 0.0261 0.002 0.0145
Entamoeba histolytica protein kinase, putative 0.0754 0.0553 0.482
Leishmania major mitogen-activated protein kinase kinase 5, putative;with=GeneDB:LmxM36.0860 0.1335 0.1181 0.1749
Entamoeba histolytica protein kinase domain containing protein 0.0261 0.002 0.0145
Schistosoma mansoni protein kinase 0.0344 0.011 0.0266
Loa Loa (eye worm) CAMK/PKD protein kinase 0.1126 0.0955 0.1229
Schistosoma mansoni tyrosine kinase 0.0261 0.002 0.0041
Echinococcus multilocularis casein kinase I gamma 0.0366 0.0133 0.0133
Echinococcus granulosus dual specificity 0.0287 0.0048 0.0066
Echinococcus multilocularis raf serine:threonine protein kinase 0.0424 0.0197 0.0197
Echinococcus multilocularis roundabout 2 0.0335 0.0099 0.0099
Loa Loa (eye worm) hypothetical protein 0.0721 0.0517 0.0663
Loa Loa (eye worm) hypothetical protein 0.1125 0.0955 0.1228
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.1453 0.1309 0.1685
Trichomonas vaginalis CAMK family protein kinase 0.0326 0.009 0.0734
Schistosoma mansoni vam6/vps39 related 0.0721 0.0517 0.1287
Entamoeba histolytica hypothetical protein 0.0264 0.0023 0.0175
Echinococcus granulosus c-Jun N-terminal kinases 0.3061 0.3049 0.4522
Trypanosoma cruzi polo-like protein kinase, putative 0.0326 0.009 0.0128
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0488 0.0266 0.0339
Echinococcus granulosus roundabout 2 0.0335 0.0099 0.0143
Giardia lamblia Kinase, AGC PKA 0.0306 0.0068 0.055
Trypanosoma brucei cdc2-related kinase 1 0.0488 0.0266 0.0389
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0321 0.0085 0.0106
Schistosoma mansoni serine/threonine protein kinase 0.0375 0.0143 0.035
Schistosoma mansoni serine/threonine protein kinase 0.1792 0.1676 0.419
Brugia malayi serine/threonine-protein kinase plk-2 0.0326 0.009 0.0112
Giardia lamblia Kinase, CMGC GSK 0.1221 0.1059 0.8958
Echinococcus multilocularis Immunoglobulin 0.0666 0.0458 0.0458
Brugia malayi hypothetical protein 0.0261 0.002 0.0021
Entamoeba histolytica serine/threonine kinase, putative 0.0261 0.002 0.0145
Trichomonas vaginalis TKL family protein kinase 0.0261 0.002 0.014
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0394 0.0164 0.0164
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0811 0.0615 0.0789
Loa Loa (eye worm) CAMK/PIM protein kinase 0.2338 0.2267 0.2922
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.1129 0.0959 0.1418
Brugia malayi Hr1 repeat family protein 0.1786 0.1669 0.215
Schistosoma mansoni tyrosine kinase 0.0457 0.0232 0.0573
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0488 0.0266 0.0389
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0804 0.0608 0.0897
Loa Loa (eye worm) hypothetical protein 0.0261 0.002 0.0021
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0804 0.0608 0.0897
Onchocerca volvulus 0.0353 0.012 0.0129
Trichomonas vaginalis TKL family protein kinase 0.0261 0.002 0.014
Schistosoma mansoni tyrosine kinase 0.0671 0.0463 0.1152
Trichomonas vaginalis TKL family protein kinase 0.0261 0.002 0.014
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0576 0.0361 0.0531
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.6472 0.6738 1
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0585 0.037 0.3478
Schistosoma mansoni tyrosine kinase 0.0261 0.002 0.0041
Entamoeba histolytica protein kinase domain containing protein 0.0436 0.0209 0.18
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0416 0.0188 0.175
Echinococcus multilocularis MAM 0.0353 0.012 0.012
Entamoeba histolytica tyrosine kinase, putative 0.0261 0.002 0.0145
Echinococcus granulosus tyrosine protein kinase Src42A 0.1129 0.0959 0.1418
Schistosoma mansoni tyrosine kinase 0.1456 0.1313 0.3279
Schistosoma mansoni tyrosine kinase 0.0923 0.0736 0.1836
Echinococcus granulosus serine:threonine protein kinase TAO1 0.2911 0.2887 0.4281
Echinococcus multilocularis cyclin dependent kinase 5 0.0488 0.0266 0.0266
Brugia malayi serine/threonine-protein kinase 6 0.0651 0.0442 0.0566
Echinococcus granulosus activin receptor type 0.4247 0.4331 0.6426
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0261 0.002 0.0041
Brugia malayi Immunoglobulin I-set domain containing protein 0.0335 0.0099 0.0124
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0261 0.002 0.0145
Echinococcus multilocularis FL cytokine receptor 0.0261 0.002 0.002
Entamoeba histolytica protein kinase domain containing protein 0.0261 0.002 0.0145
Entamoeba histolytica protein kinase domain containing protein 0.0261 0.002 0.0145
Plasmodium falciparum protein kinase, putative 0.0436 0.0209 0.1945
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.1118 0.0947 0.1401

Activities

Activity type Activity value Assay description Source Reference
EC50 (functional) = 50 nM Agonist activity at PR expressed in african green monkey CV-1 cells by luciferase reporter assay ChEMBL. 19595590
Emax (functional) = 40 % Agonist activity at PR expressed in african green monkey CV-1 cells by luciferase reporter assay relative to progesterone ChEMBL. 19595590
IC50 (binding) = 25 nM Binding affinity to PR by fluorescence polarization based competition binding assay ChEMBL. 19595590

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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