Detailed information for compound 1143547

Basic information

Technical information
  • TDR Targets ID: 1143547
  • Name: N-(naphthalen-2-ylmethyl)-2-[2-[2-(naphthalen -2-ylmethylamino)ethoxy]ethoxy]ethanamine
  • MW: 428.566 | Formula: C28H32N2O2
  • H donors: 2 H acceptors: 0 LogP: 4.56 Rotable bonds: 13
    Rule of 5 violations (Lipinski): 1
  • SMILES: C(OCCOCCNCc1ccc2c(c1)cccc2)CNCc1ccc2c(c1)cccc2
  • InChi: 1S/C28H32N2O2/c1-3-7-27-19-23(9-11-25(27)5-1)21-29-13-15-31-17-18-32-16-14-30-22-24-10-12-26-6-2-4-8-28(26)20-24/h1-12,19-20,29-30H,13-18,21-22H2
  • InChiKey: LPJXSOCNXHPFOI-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N-(2-naphthylmethyl)-2-[2-[2-(2-naphthylmethylamino)ethoxy]ethoxy]ethanamine
  • 2-naphthylmethyl-[2-[2-[2-(2-naphthylmethylamino)ethoxy]ethoxy]ethyl]amine
  • NCI60_034253

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus importin subunit beta 1 0.003 0.0013 0.0013
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0192 0.0955 0.1952
Entamoeba histolytica cysteine protease, putative 0.0451 0.2458 0.5215
Schistosoma mansoni cathepsin S (C01 family) 0.0192 0.0955 0.0955
Loa Loa (eye worm) hypothetical protein 0.0087 0.0344 0.0344
Loa Loa (eye worm) papain family cysteine protease containing protein 0.083 0.4663 0.4663
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0077 0.0282 0.0282
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0451 0.2458 0.2458
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.083 0.4663 1
Mycobacterium ulcerans hypothetical protein 0.0167 0.0807 1
Entamoeba histolytica cysteine proteinase, putative 0.0451 0.2458 0.5215
Schistosoma mansoni jumonji domain containing protein 0.0227 0.1158 0.1158
Giardia lamblia Cathepsin L-like protease 0.0192 0.0955 0.2365
Onchocerca volvulus 0.0082 0.0311 0.0645
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0286 0.1499 0.5075
Echinococcus granulosus peregrin 0.0102 0.0427 0.0427
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0171 0.0832 0.1784
Entamoeba histolytica hypothetical protein 0.0192 0.0955 0.1952
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.083 0.4663 1
Loa Loa (eye worm) hypothetical protein 0.0192 0.0955 0.0955
Echinococcus granulosus cathepsin L 0.0192 0.0955 0.0955
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0673 0.3752 0.3752
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0084 0.0323 0.0323
Toxoplasma gondii NADPH-glutathione reductase 0.0043 0.0089 0.019
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0043 0.0089 0.019
Mycobacterium ulcerans esterase/lipase LipP 0.0082 0.0311 0.3089
Echinococcus multilocularis cathepsin L 0.0451 0.2458 0.2458
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0077 0.0282 0.0606
Plasmodium falciparum serine repeat antigen 7 0.0192 0.0955 0.2048
Loa Loa (eye worm) beta-lactamase 0.0082 0.0311 0.0311
Leishmania major cathepsin L-like protease 0.083 0.4663 1
Brugia malayi hypothetical protein 0.0038 0.0056 0.0056
Schistosoma mansoni hypothetical protein 0.0084 0.0323 0.0323
Toxoplasma gondii HEAT repeat-containing protein 0.003 0.0013 0.0029
Trichomonas vaginalis chromobox protein, putative 0.0068 0.0233 0.0483
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0211 0.1062 0.1062
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0192 0.0955 0.2033
Plasmodium falciparum ataxin-2 like protein, putative 0.005 0.0127 0.0273
Loa Loa (eye worm) hypothetical protein 0.015 0.0707 0.0707
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.083 0.4663 1
Brugia malayi follicle stimulating hormone receptor 0.05 0.2745 0.2745
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0054 0.0152 0.0152
Giardia lamblia Cathepsin L precursor 0.0192 0.0955 0.2365
Loa Loa (eye worm) cathepsin B 0.0673 0.3752 0.3752
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0192 0.0955 0.2033
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0057 0.017 0.0293
Echinococcus granulosus cathepsin b 0.1747 1 1
Echinococcus granulosus survival motor neuron protein 1 0.0231 0.1181 0.1181
Loa Loa (eye worm) hypothetical protein 0.0571 0.316 0.316
Giardia lamblia Cathepsin L precursor 0.0192 0.0955 0.2365
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0192 0.0955 0.2048
Brugia malayi Papain family cysteine protease containing protein 0.0451 0.2458 0.2458
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0057 0.017 0.0293
Treponema pallidum exodeoxyribonuclease (exoA) 0.0077 0.0282 1
Trypanosoma cruzi cytochrome P450, putative 0.0129 0.0588 0.0588
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0013 0.0029
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.1747 1 1
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0057 0.017 0.1134
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0051 0.0133 0.0267
Loa Loa (eye worm) hypothetical protein 0.0038 0.0059 0.0059
Giardia lamblia Hypothetical protein 0.0192 0.0955 0.2365
Loa Loa (eye worm) MH2 domain-containing protein 0.0368 0.1979 0.1979
Entamoeba histolytica cysteine protease, putative 0.0451 0.2458 0.5215
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0068 0.0128
Trypanosoma cruzi cysteine peptidase, putative 0.0258 0.1339 0.1339
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0451 0.2458 0.2458
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0192 0.0955 0.2365
Giardia lamblia Cysteine protease 0.0192 0.0955 0.2365
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0057 0.017 0.0293
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0057 0.017 0.0293
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.083 0.4663 1
Loa Loa (eye worm) hypothetical protein 0.0082 0.0311 0.0311
Brugia malayi Pre-SET motif family protein 0.0211 0.1062 0.1062
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0171 0.0832 0.1784
Entamoeba histolytica cysteine protease, putative 0.0192 0.0955 0.1952
Brugia malayi Cathepsin L-like precursor 0.083 0.4663 0.4663
Giardia lamblia Histone acetyltransferase GCN5 0.0157 0.0749 0.1803
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0068 0.0128
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0398 0.0836
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0043 0.0089 0.0089
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0076 0.0144
Loa Loa (eye worm) hypothetical protein 0.0192 0.0955 0.0955
Brugia malayi Cytochrome P450 family protein 0.0134 0.0614 0.0614
Trypanosoma brucei polo-like protein kinase 0.0097 0.0398 0.0853
Giardia lamblia Cathepsin B precursor 0.0192 0.0955 0.2365
Echinococcus multilocularis chromobox protein 1 0.0068 0.0233 0.0233
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0057 0.017 0.0293
Loa Loa (eye worm) glutathione reductase 0.0125 0.0565 0.0565
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0077 0.0282 0.0606
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0034 0.0031 0.0031
Leishmania major cathepsin L-like protease 0.083 0.4663 1
Trypanosoma cruzi cysteine proteinase, putative 0.0451 0.2458 0.2458
Echinococcus granulosus cytochrome P450 2K1 0.0057 0.017 0.017
Brugia malayi cathepsin F-like cysteine proteinase 0.0192 0.0955 0.0955
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0057 0.017 0.0293
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0051 0.0133 0.0267
Schistosoma mansoni cathepsin F (C01 family) 0.083 0.4663 0.4663
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0139 0.0647 0.0647
Schistosoma mansoni cpg binding protein 0.0186 0.0918 0.0918
Brugia malayi cathepsin L-like cysteine proteinase 0.0192 0.0955 0.0955
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1747 1 1
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0057 0.017 0.0293
Echinococcus multilocularis beta LACTamase domain containing family member 0.0082 0.0311 0.0311
Brugia malayi Cathepsin L-like precursor 0.083 0.4663 0.4663
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0192 0.0955 0.2365
Giardia lamblia Cathepsin L precursor 0.0192 0.0955 0.2365
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0192 0.0955 0.0955
Plasmodium falciparum serine repeat antigen 3 0.0192 0.0955 0.2048
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0077 0.0282 0.0606
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0192 0.0955 0.0955
Plasmodium vivax unspecified product 0.0258 0.1339 0.2872
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0077 0.0282 0.0282
Loa Loa (eye worm) hypothetical protein 0.003 0.0011 0.0011
Echinococcus granulosus chromobox protein 1 0.0068 0.0233 0.0233
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0139 0.0647 0.0647
Brugia malayi acetyltransferase, GNAT family protein 0.0582 0.3223 0.3223
Brugia malayi Latrophilin receptor protein 2 0.0084 0.0323 0.0323
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.083 0.4663 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.083 0.4663 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.083 0.4663 1
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0043 0.0089 0.019
Brugia malayi cytochrome P450 0.0057 0.017 0.017
Brugia malayi PHD-finger family protein 0.0039 0.006 0.006
Plasmodium falciparum cysteine proteinase falcipain 2a 0.083 0.4663 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.083 0.4663 1
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0043 0.0089 0.019
Onchocerca volvulus 0.0192 0.0955 0.203
Loa Loa (eye worm) hypothetical protein 0.083 0.4663 0.4663
Toxoplasma gondii histone lysine methyltransferase SET1 0.0349 0.1865 0.3999
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0063 0.0201 0.0405
Plasmodium falciparum serine repeat antigen 4 0.0192 0.0955 0.2048
Schistosoma mansoni survival motor neuron protein 0.0047 0.011 0.011
Schistosoma mansoni cathepsin s 0.0258 0.1339 0.1339
Trypanosoma cruzi cruzipain precursor, putative 0.0258 0.1339 0.1339
Entamoeba histolytica cysteine proteinase 2 0.0451 0.2458 0.5215
Onchocerca volvulus Cathepsin L homolog 0.083 0.4663 1
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0057 0.017 0.1134
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0082 0.0311 0.0799
Trypanosoma cruzi polo-like protein kinase, putative 0.0097 0.0398 0.0398
Loa Loa (eye worm) ctsf protein 0.083 0.4663 0.4663
Leishmania major cysteine peptidase A (CPA) 0.083 0.4663 1
Echinococcus granulosus dnaJ subfamily B 0.1249 0.7103 0.7103
Echinococcus granulosus GPCR family 2 0.0084 0.0323 0.0323
Plasmodium falciparum glutathione reductase 0.0043 0.0089 0.019
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0571 0.316 0.316
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0582 0.3223 0.3223
Loa Loa (eye worm) thioredoxin reductase 0.0125 0.0565 0.0565
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0045 0.0095 0.0095
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0258 0.1339 0.1339
Plasmodium falciparum thioredoxin reductase 0.0043 0.0089 0.019
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0171 0.0832 0.1784
Plasmodium falciparum serine repeat antigen 9 0.0192 0.0955 0.2048
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0043 0.0089 0.019
Echinococcus multilocularis jumonji domain containing protein 0.0121 0.0543 0.0543
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0045 0.0095 0.0095
Plasmodium vivax unspecified product 0.0451 0.2458 0.5272
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0077 0.0282 0.0492
Trypanosoma cruzi major cysteine proteinase, putative 0.0192 0.0955 0.0955
Toxoplasma gondii hypothetical protein 0.0051 0.0133 0.0286
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0057 0.017 0.1134
Giardia lamblia Cathepsin L precursor 0.0192 0.0955 0.2365
Echinococcus multilocularis cathepsin b 0.1747 1 1
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0192 0.0955 0.2048
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0082 0.0311 0.0799
Echinococcus granulosus cathepsin b 0.1747 1 1
Loa Loa (eye worm) hypothetical protein 0.0258 0.1339 0.1339
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0057 0.017 0.1134
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0192 0.0955 0.0955
Onchocerca volvulus 0.0571 0.316 0.6769
Loa Loa (eye worm) hypothetical protein 0.0039 0.006 0.006
Giardia lamblia Cathepsin B precursor 0.0192 0.0955 0.2365
Entamoeba histolytica cysteine protease, putative 0.0451 0.2458 0.5215
Entamoeba histolytica cysteine protease, putative 0.0192 0.0955 0.1952
Mycobacterium tuberculosis Conserved protein 0.0082 0.0311 0.0799
Loa Loa (eye worm) cytochrome P450 family protein 0.0134 0.0614 0.0614
Trypanosoma brucei PAB1-binding protein , putative 0.005 0.0127 0.0273
Loa Loa (eye worm) hypothetical protein 0.0082 0.0311 0.0311
Loa Loa (eye worm) hypothetical protein 0.0571 0.316 0.316
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0047 0.011 0.011
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0043 0.0089 0.0089
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0057 0.017 0.1134
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0043 0.0089 0.0089
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0051 0.0133 0.0267
Trypanosoma cruzi cruzipain precursor, putative 0.083 0.4663 0.4663
Schistosoma mansoni cytochrome P450 0.0057 0.017 0.017
Plasmodium falciparum cysteine proteinase falcipain 1 0.0451 0.2458 0.5272
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0258 0.1339 0.1339
Giardia lamblia Cathepsin B precursor 0.0192 0.0955 0.2365
Onchocerca volvulus 0.0082 0.0311 0.0645
Entamoeba histolytica cysteine protease, putative 0.083 0.4663 1
Trichomonas vaginalis ap endonuclease, putative 0.0077 0.0282 0.0588
Entamoeba histolytica cysteine protease, putative 0.0451 0.2458 0.5215
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0192 0.0955 0.2033
Entamoeba histolytica cysteine proteinase 1, putative 0.0451 0.2458 0.5215
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0451 0.2458 0.5272
Plasmodium falciparum serine repeat antigen 1 0.0192 0.0955 0.2048
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0318 0.1685 0.5742
Loa Loa (eye worm) jmjC domain-containing protein 0.0116 0.0509 0.0509
Brugia malayi Papain family cysteine protease containing protein 0.0451 0.2458 0.2458
Toxoplasma gondii ABC1 family protein 0.0082 0.0311 0.0666
Mycobacterium tuberculosis Conserved hypothetical protein 0.0167 0.0807 0.2585
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0129 0.0588 0.6954
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0034 0.0031 0.0031
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0082 0.0311 0.0311
Brugia malayi Papain family cysteine protease containing protein 0.0192 0.0955 0.0955
Plasmodium falciparum phd finger protein, putative 0.0087 0.0344 0.0738
Loa Loa (eye worm) PHD-finger family protein 0.0087 0.0344 0.0344
Trichomonas vaginalis helicase, putative 0.004 0.0068 0.0128
Toxoplasma gondii PHD-finger domain-containing protein 0.0087 0.0344 0.0738
Brugia malayi Cathepsin L-like precursor 0.0571 0.316 0.316
Brugia malayi cathepsin F-like cysteine proteinase 0.0258 0.1339 0.1339
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0043 0.0089 0.0089
Echinococcus granulosus cathepsin l1 0.0571 0.316 0.316
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0059 0.0108
Trypanosoma brucei cysteine peptidase C (CPC) 0.0673 0.3752 0.8046
Mycobacterium ulcerans aldehyde dehydrogenase 0.0063 0.0201 0.1566
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0038 0.0056 0.0056
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.083 0.4663 1
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0057 0.017 0.0293
Plasmodium falciparum serine repeat antigen 6 0.0192 0.0955 0.2048
Loa Loa (eye worm) hypothetical protein 0.0571 0.316 0.316
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0192 0.0955 0.0955
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1732 0.9915 0.9915
Onchocerca volvulus 0.083 0.4663 1
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0097 0.0398 0.0853
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0264 0.1375 0.1375
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0192 0.0955 0.2033
Trypanosoma cruzi cysteine peptidase, putative 0.083 0.4663 0.4663
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0192 0.0955 0.2048
Trichomonas vaginalis penicillin-binding protein, putative 0.0082 0.0311 0.0649
Plasmodium falciparum histone acetyltransferase GCN5 0.0157 0.0749 0.1606
Echinococcus granulosus histone acetyltransferase KAT2B 0.0566 0.3128 0.3128
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0068 0.0128
Loa Loa (eye worm) hypothetical protein 0.014 0.0652 0.0652
Plasmodium vivax vivapain-2 0.083 0.4663 1
Schistosoma mansoni aldehyde dehydrogenase 0.0063 0.0201 0.0201
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0043 0.0089 0.0089
Loa Loa (eye worm) jmjC domain-containing protein 0.018 0.0885 0.0885
Giardia lamblia Cathepsin L precursor 0.0192 0.0955 0.2365
Schistosoma mansoni hypothetical protein 0.0181 0.0888 0.0888
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0057 0.017 0.0293
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0077 0.0282 0.0282
Plasmodium falciparum glutathione reductase 0.0125 0.0565 0.1212
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0398 0.0836
Leishmania major cathepsin L-like protease 0.083 0.4663 1
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0057 0.017 0.0293
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0057 0.017 0.1134
Leishmania major hypothetical protein, conserved 0.0082 0.0311 0.0666
Mycobacterium tuberculosis Probable lipase LipE 0.0082 0.0311 0.0799
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0059 0.0108
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0043 0.0089 0.019
Plasmodium vivax thioredoxin reductase, putative 0.0125 0.0565 0.1212
Giardia lamblia Cathepsin B precursor 0.0192 0.0955 0.2365
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0057 0.017 0.0293
Mycobacterium leprae Probable lipase LipE 0.0082 0.0311 0.0927
Echinococcus granulosus chromobox protein 1 0.0068 0.0233 0.0233
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0192 0.0955 0.2033
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0192 0.0955 0.2048
Entamoeba histolytica cysteine protease, putative 0.0451 0.2458 0.5215
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0057 0.017 0.017
Schistosoma mansoni jumonji/arid domain-containing protein 0.0116 0.0509 0.0509
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0068 0.0128
Echinococcus multilocularis chromobox protein 1 0.0068 0.0233 0.0233
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0043 0.0089 0.0089
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0051 0.0133 0.0267
Onchocerca volvulus 0.083 0.4663 1
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0084 0.0323 0.0323
Brugia malayi Cytochrome P450 family protein 0.0129 0.0588 0.0588
Brugia malayi fibroinase precursor 0.0192 0.0955 0.0955
Toxoplasma gondii LsmAD domain-containing protein 0.005 0.0127 0.0273
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0192 0.0955 0.0955
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.083 0.4663 1
Entamoeba histolytica cysteine protease, putative 0.0192 0.0955 0.1952
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0192 0.0955 0.2033
Plasmodium falciparum serine repeat antigen 2 0.0192 0.0955 0.2048
Loa Loa (eye worm) hypothetical protein 0.0034 0.0031 0.0031
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0192 0.0955 0.0955
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0045 0.0097 0.0097
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0097 0.0398 0.0398
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0192 0.0955 0.0955
Echinococcus granulosus histone acetyltransferase KAT2B 0.0171 0.0832 0.0832
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0045 0.0097 0.0097
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0068 0.0128
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0317 0.168 0.3602
Echinococcus granulosus thioredoxin glutathione reductase 0.0127 0.0575 0.0575
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0043 0.0089 0.0089
Schistosoma mansoni hypothetical protein 0.0084 0.0323 0.0323
Brugia malayi beta-lactamase family protein 0.0082 0.0311 0.0311
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0057 0.017 0.1134
Brugia malayi cathepsin Z-like cysteine proteinase 0.0192 0.0955 0.0955
Schistosoma mansoni cpg binding protein 0.0176 0.086 0.086
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0057 0.017 0.1134
Leishmania major cytochrome p450-like protein 0.0129 0.0588 0.1261
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0057 0.017 0.1134
Entamoeba histolytica cysteine protease, putative 0.0192 0.0955 0.1952
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0192 0.0955 0.2033
Schistosoma mansoni aldehyde dehydrogenase 0.0063 0.0201 0.0201
Loa Loa (eye worm) hypothetical protein 0.0192 0.0955 0.0955
Leishmania major cytochrome p450-like protein 0.0057 0.017 0.0365
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0192 0.0955 0.2365
Loa Loa (eye worm) CXXC zinc finger family protein 0.0176 0.086 0.086
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.083 0.4663 1
Trichomonas vaginalis chromobox protein, putative 0.0068 0.0233 0.0483
Brugia malayi PHD-finger family protein 0.0087 0.0344 0.0344
Echinococcus multilocularis importin subunit beta 1 0.003 0.0013 0.0013
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0056 0.0159 0.0159
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0192 0.0955 0.2033
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0192 0.0955 0.2048
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0398 0.0836
Schistosoma mansoni hypothetical protein 0.0084 0.0323 0.0323
Echinococcus granulosus jumonji domain containing protein 0.0121 0.0543 0.0543
Mycobacterium ulcerans beta-lactamase 0.0082 0.0311 0.3089
Brugia malayi AF-10 protein 0.0029 0.0002 0.0002
Schistosoma mansoni ap endonuclease 0.0077 0.0282 0.0282
Echinococcus granulosus geminin 0.0868 0.4885 0.4885
Trichomonas vaginalis conserved hypothetical protein 0.0192 0.0955 0.2033
Schistosoma mansoni kinase 0.0049 0.0121 0.0121
Schistosoma mansoni hypothetical protein 0.0057 0.017 0.017
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0057 0.017 0.0365
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0318 0.1685 1
Loa Loa (eye worm) histone methyltransferase 0.0056 0.0159 0.0159
Echinococcus granulosus snurportin 1 0.0325 0.1729 0.1729
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0057 0.017 0.1134
Echinococcus granulosus cysteine protease 0.0451 0.2458 0.2458
Loa Loa (eye worm) hypothetical protein 0.0072 0.0254 0.0254
Echinococcus multilocularis GPCR, family 2 0.0084 0.0323 0.0323
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0077 0.0282 0.0282
Onchocerca volvulus Cathepsin L homolog 0.0192 0.0955 0.203
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0057 0.017 0.1134
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0192 0.0955 0.2048
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0002 0.0004
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0043 0.0089 0.019
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0043 0.0089 0.0089
Plasmodium vivax serine-repeat antigen (SERA) 0.0192 0.0955 0.2048
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0077 0.0282 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.0031 0.0031
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0043 0.0089 0.019
Loa Loa (eye worm) hypothetical protein 0.0231 0.1181 0.1181
Entamoeba histolytica cysteine protease, putative 0.0451 0.2458 0.5215
Trichomonas vaginalis glutathione reductase, putative 0.0043 0.0089 0.0172
Onchocerca volvulus 0.0047 0.011 0.0215
Leishmania major cytochrome p450-like protein 0.0057 0.017 0.0365
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0398 0.0836
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0192 0.0955 0.2048
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0057 0.017 0.0293
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0077 0.0282 0.0282
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0325 0.1729 0.1729
Loa Loa (eye worm) follicle stimulating hormone receptor 0.05 0.2745 0.2745
Entamoeba histolytica cysteine protease, putative 0.0192 0.0955 0.1952
Trichomonas vaginalis set domain proteins, putative 0.0239 0.1228 0.262
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0057 0.017 0.0293
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.0029 0.0002 0.0004
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0038 0.0056 0.0056
Toxoplasma gondii thioredoxin reductase 0.0125 0.0565 0.1212
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1747 1 1
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0398 0.0836
Loa Loa (eye worm) hypothetical protein 0.005 0.0127 0.0127
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0139 0.0647 0.0647
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.083 0.4663 1
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0192 0.0955 0.2033
Mycobacterium ulcerans aldehyde dehydrogenase 0.0063 0.0201 0.1566
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.083 0.4663 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.083 0.4663 1
Loa Loa (eye worm) fibroinase 0.083 0.4663 0.4663
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0029 0.0002 0.0004
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0084 0.0323 0.0323
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0374 0.2014 0.2014
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.0002 0.0002
Brugia malayi Papain family cysteine protease containing protein 0.083 0.4663 0.4663
Mycobacterium tuberculosis Conserved protein 0.0082 0.0311 0.0799
Trichomonas vaginalis ap endonuclease, putative 0.0077 0.0282 0.0588
Mycobacterium ulcerans lipase LipD 0.0082 0.0311 0.3089
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0192 0.0955 0.2048
Onchocerca volvulus 0.083 0.4663 1
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0192 0.0955 0.2048
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0114 0.0227
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0673 0.3752 0.3752
Entamoeba histolytica cysteine proteinase, putative 0.0451 0.2458 0.5215
Entamoeba histolytica serine/threonine protein kinase, putative 0.0097 0.0398 0.0742
Mycobacterium ulcerans hypothetical protein 0.0082 0.0311 0.3089
Giardia lamblia Cysteine protease 0.0192 0.0955 0.2365
Onchocerca volvulus 0.0045 0.0096 0.0184
Schistosoma mansoni cathepsin F (C01 family) 0.083 0.4663 0.4663
Brugia malayi F/Y-rich N-terminus family protein 0.0083 0.0321 0.0321
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0043 0.0089 0.0089
Entamoeba histolytica cysteine protease, putative 0.0451 0.2458 0.5215
Loa Loa (eye worm) hypothetical protein 0.003 0.0013 0.0013
Giardia lamblia Cathepsin L precursor 0.0192 0.0955 0.2365
Echinococcus multilocularis 0.0057 0.017 0.017
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0057 0.017 0.1134
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0068 0.0128
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0032 0.0022 0.0022
Brugia malayi Cathepsin L-like precursor 0.083 0.4663 0.4663
Echinococcus granulosus beta LACTamase domain containing family member 0.0082 0.0311 0.0311
Brugia malayi Calcitonin receptor-like protein seb-1 0.0264 0.1375 0.1375
Echinococcus multilocularis cathepsin L cysteine protease 0.083 0.4663 0.4663
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0051 0.0133 0.0267
Echinococcus multilocularis dnaJ subfamily B 0.1249 0.7103 0.7103
Onchocerca volvulus 0.083 0.4663 1
Loa Loa (eye worm) hypothetical protein 0.0192 0.0955 0.0955
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0045 0.0095 0.0095
Toxoplasma gondii cathepsin CPC2 0.0192 0.0955 0.2048
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0013 0.0029
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0056 0.0159 0.0159
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0192 0.0955 0.2033
Brugia malayi Cathepsin L-like precursor 0.0258 0.1339 0.1339
Brugia malayi Cathepsin L-like precursor 0.083 0.4663 0.4663
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.083 0.4663 1
Brugia malayi hypothetical protein 0.0032 0.0024 0.0024
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0057 0.017 0.1134
Mycobacterium tuberculosis Probable lipase LipD 0.0082 0.0311 0.0799
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0068 0.0128
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0571 0.316 0.677
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0139 0.0647 0.0647
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0043 0.0089 0.5
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0043 0.0089 0.0089
Brugia malayi serine/threonine-protein kinase plk-2 0.0097 0.0398 0.0398
Entamoeba histolytica cysteine protease, putative 0.0451 0.2458 0.5215
Trypanosoma cruzi hypothetical protein, conserved 0.0082 0.0311 0.0311
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0286 0.15 0.15
Brugia malayi Cathepsin L-like cysteine proteinase 0.0571 0.316 0.316
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.083 0.4663 1
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.015 0.0709 0.1519
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0082 0.0311 0.0799
Brugia malayi Importin beta-1 subunit 0.003 0.0013 0.0013
Echinococcus multilocularis geminin 0.0868 0.4885 0.4885
Brugia malayi Cytochrome P450 family protein 0.0129 0.0588 0.0588
Mycobacterium tuberculosis Probable esterase LipL 0.0082 0.0311 0.0799
Echinococcus multilocularis peregrin 0.0102 0.0427 0.0427
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1747 1 1
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0192 0.0955 0.0955
Leishmania major cathepsin L-like protease 0.083 0.4663 1
Onchocerca volvulus 0.083 0.4663 1
Brugia malayi jmjC domain containing protein 0.0286 0.15 0.15
Trichomonas vaginalis D-aminoacylase, putative 0.0082 0.0311 0.0649
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.083 0.4663 1
Brugia malayi Bromodomain containing protein 0.0102 0.0427 0.0427
Entamoeba histolytica cysteine proteinase, putative 0.0451 0.2458 0.5215
Entamoeba histolytica cysteine proteinase, putative 0.083 0.4663 1
Trypanosoma cruzi cysteine peptidase, putative 0.083 0.4663 0.4663
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0192 0.0955 0.2048
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.083 0.4663 1
Brugia malayi Cathepsin L-like precursor 0.083 0.4663 0.4663
Loa Loa (eye worm) hypothetical protein 0.0082 0.0311 0.0311
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0057 0.017 0.0293
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0192 0.0955 0.0955
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0038 0.0058 0.0058
Echinococcus multilocularis survival motor neuron protein 1 0.0231 0.1181 0.1181
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0082 0.0311 0.0311
Schistosoma mansoni transcription factor LCR-F1 0.0038 0.0056 0.0056
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0057 0.017 0.0365
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0451 0.2458 0.5263
Loa Loa (eye worm) hypothetical protein 0.0082 0.0311 0.0311
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0057 0.017 0.0293
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0451 0.2458 0.2458
Schistosoma mansoni hypothetical protein 0.0029 0.0002 0.0002
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.083 0.4663 1
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0192 0.0955 0.0955
Plasmodium falciparum cysteine proteinase falcipain 3 0.083 0.4663 1
Brugia malayi cathepsin L-like precursor 0.0571 0.316 0.316
Plasmodium falciparum serine repeat antigen 8 0.0192 0.0955 0.2048
Schistosoma mansoni cathepsin C 0.0192 0.0955 0.0955
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0171 0.0832 0.1769
Mycobacterium leprae conserved hypothetical protein 0.0082 0.0311 0.0927
Onchocerca volvulus 0.0082 0.0311 0.0645
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0077 0.0282 0.0697
Echinococcus multilocularis cathepsin b 0.1747 1 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.083 0.4663 1
Loa Loa (eye worm) heterochromatin protein 1 0.0068 0.0233 0.0233
Leishmania major trypanothione reductase 0.0125 0.0565 0.1212
Brugia malayi MH2 domain containing protein 0.0368 0.1979 0.1979
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0029 0.0002 0.0004
Onchocerca volvulus 0.0239 0.1228 0.2617
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0286 0.1499 0.5075
Schistosoma mansoni hypothetical protein 0.0868 0.4885 0.4885
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0192 0.0955 0.2365
Plasmodium falciparum ataxin-2 like protein, putative 0.005 0.0127 0.0273
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0038 0.0058 0.0058
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0521 0.2868 1
Schistosoma mansoni chromobox protein 0.0068 0.0233 0.0233
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0051 0.0133 0.0267
Toxoplasma gondii exonuclease III APE 0.0077 0.0282 0.0606
Plasmodium vivax vivapain-1 0.0451 0.2458 0.5272
Plasmodium vivax hypothetical protein, conserved 0.0039 0.0064 0.0138
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.083 0.4663 1
Echinococcus multilocularis cysteine protease 0.083 0.4663 0.4663
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0192 0.0955 0.2048
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.083 0.4663 1
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0264 0.1375 0.1375
Brugia malayi Heterochromatin protein 1 0.0068 0.0233 0.0233
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0063 0.0201 0.0431
Brugia malayi hypothetical protein 0.005 0.0127 0.0127
Onchocerca volvulus Serine\/threonine kinase homolog 0.0097 0.0398 0.0832
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0398 0.0836
Leishmania major cathepsin L-like protease 0.083 0.4663 1
Brugia malayi RNA, U transporter 1 0.0087 0.034 0.034
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.083 0.4663 1
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0192 0.0955 0.2048
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0063 0.0201 0.0201
Loa Loa (eye worm) hypothetical protein 0.0192 0.0955 0.0955
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0114 0.0227
Trichomonas vaginalis D-aminoacylase, putative 0.0082 0.0311 0.0649
Toxoplasma gondii cathepsin CPC1 0.0192 0.0955 0.2048
Leishmania major cathepsin L-like protease 0.083 0.4663 1
Entamoeba histolytica cysteine protease, putative 0.0451 0.2458 0.5215
Giardia lamblia PHD finger protein 15 0.0087 0.0344 0.0697
Loa Loa (eye worm) hypothetical protein 0.0258 0.1339 0.1339
Plasmodium vivax importin-beta 2, putative 0.003 0.0013 0.0029
Loa Loa (eye worm) hypothetical protein 0.0181 0.0888 0.0888
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0673 0.3752 0.8046
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0063 0.0201 0.0201
Giardia lamblia Cathepsin L-like protease 0.0192 0.0955 0.2365
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0125 0.0565 0.1714
Brugia malayi hypothetical protein 0.0231 0.1181 0.1181
Onchocerca volvulus Cathepsin L homolog 0.083 0.4663 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.083 0.4663 1
Trypanosoma cruzi major cysteine proteinase, putative 0.0192 0.0955 0.0955
Schistosoma mansoni cpg binding protein 0.0186 0.0918 0.0918
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0039 0.0064 0.0138
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0043 0.0089 0.0089
Trichomonas vaginalis mercuric reductase, putative 0.0043 0.0089 0.0172
Echinococcus multilocularis cathepsin l cysteine peptidase 0.083 0.4663 0.4663
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0192 0.0955 0.0955
Mycobacterium tuberculosis Probable reductase 0.0286 0.1499 0.5075
Echinococcus granulosus histone lysine methyltransferase setb 0.0034 0.0031 0.0031
Onchocerca volvulus 0.083 0.4663 1
Leishmania major mitochondrial DNA polymerase beta 0.0317 0.168 0.3602
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.083 0.4663 1
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0057 0.017 0.1134
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0077 0.0282 0.0529
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.083 0.4663 1
Toxoplasma gondii cytochrome p450 superfamily protein 0.0057 0.017 0.0365
Onchocerca volvulus Alhambra homolog 0.0087 0.0344 0.0717
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0043 0.0089 0.019
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0451 0.2458 0.5263
Trypanosoma brucei hypothetical protein, conserved 0.0082 0.0311 0.0666
Trichomonas vaginalis conserved hypothetical protein 0.0192 0.0955 0.2033
Echinococcus multilocularis cpg binding protein 0.0186 0.0918 0.0918
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0087 0.0344 0.0344
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.083 0.4663 1
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0043 0.0089 0.019
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0057 0.017 0.1134
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.083 0.4663 1
Loa Loa (eye worm) hypothetical protein 0.0082 0.0311 0.0311
Schistosoma mansoni cathepsin B (C01 family) 0.0192 0.0955 0.0955
Trichomonas vaginalis penicillin-binding protein, putative 0.0082 0.0311 0.0649
Mycobacterium tuberculosis Probable hydrolase 0.0082 0.0311 0.0799
Entamoeba histolytica cysteine protease, putative 0.0451 0.2458 0.5215
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0068 0.0128
Trypanosoma cruzi cysteine peptidase, putative 0.083 0.4663 0.4663
Toxoplasma gondii cathepsin B 0.0673 0.3752 0.8046
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0139 0.0647 0.0647
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0317 0.168 0.168
Trypanosoma cruzi cysteine peptidase, putative 0.0451 0.2458 0.2458
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0045 0.0096 0.0096
Schistosoma mansoni hypothetical protein 0.0087 0.0344 0.0344
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0057 0.017 0.0293
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0139 0.0647 0.0647
Loa Loa (eye worm) cytochrome P450 0.0057 0.017 0.017
Echinococcus multilocularis cysteine protease 0.083 0.4663 0.4663
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0057 0.017 0.1134
Echinococcus granulosus cathepsin l cysteine peptidase 0.083 0.4663 0.4663
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0057 0.017 0.1134
Trypanosoma cruzi hypothetical protein, conserved 0.0082 0.0311 0.0311
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0097 0.0398 0.0398
Echinococcus granulosus cathepsin L cysteine protease 0.0451 0.2458 0.2458
Brugia malayi hypothetical protein 0.014 0.0652 0.0652
Loa Loa (eye worm) latrophilin receptor protein 2 0.0084 0.0323 0.0323
Loa Loa (eye worm) hypothetical protein 0.0192 0.0955 0.0955
Toxoplasma gondii aldehyde dehydrogenase 0.0063 0.0201 0.0431
Trypanosoma brucei trypanothione reductase 0.0125 0.0565 0.1212
Toxoplasma gondii preprocathepsin c precursor, putative 0.0192 0.0955 0.2048
Entamoeba histolytica cysteine protease, putative 0.0451 0.2458 0.5215
Entamoeba histolytica cysteine proteinase, putative 0.0571 0.316 0.6737
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.0031 0.0031
Toxoplasma gondii PHD-finger domain-containing protein 0.0087 0.0344 0.0738
Plasmodium falciparum thioredoxin reductase 0.0125 0.0565 0.1212
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0057 0.017 0.017
Echinococcus multilocularis snurportin 1 0.0325 0.1729 0.1729
Trypanosoma cruzi cysteine proteinase, putative 0.0451 0.2458 0.2458
Onchocerca volvulus Huntingtin homolog 0.014 0.0652 0.1379
Brugia malayi beta-lactamase family protein 0.0082 0.0311 0.0311
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0077 0.0282 0.0606
Echinococcus granulosus lysine specific demethylase 5A 0.0116 0.0509 0.0509
Brugia malayi Cathepsin L-like precursor 0.083 0.4663 0.4663
Echinococcus multilocularis cathepsin l cysteine peptidase 0.083 0.4663 0.4663
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0286 0.1499 0.5075
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0192 0.0955 0.2033
Giardia lamblia Cathepsin B precursor 0.0673 0.3752 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.0031 0.0031
Echinococcus multilocularis cathepsin L 0.0192 0.0955 0.0955
Schistosoma mansoni hypothetical protein 0.0084 0.0323 0.0323
Loa Loa (eye worm) transcription factor SMAD2 0.0368 0.1979 0.1979
Plasmodium vivax ataxin-2 like protein, putative 0.005 0.0127 0.0273
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0033 0.0025 0.0036
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0451 0.2458 0.5272
Plasmodium vivax SET domain protein, putative 0.0034 0.0031 0.0067
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0073 0.0263 0.0263
Loa Loa (eye worm) hypothetical protein 0.014 0.0652 0.0652
Trichomonas vaginalis esterase, putative 0.0082 0.0311 0.0649
Schistosoma mansoni jumonji/arid domain-containing protein 0.0116 0.0509 0.0509
Trypanosoma cruzi trypanothione reductase, putative 0.0125 0.0565 0.0565
Giardia lamblia Cathepsin B precursor 0.0673 0.3752 1
Echinococcus granulosus cathepsin l1 0.083 0.4663 0.4663
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0034 0.0031 0.0067
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0032 0.0022 0.0022
Schistosoma mansoni hypothetical protein 0.1249 0.7103 0.7103
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0192 0.0955 0.2033
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.083 0.4663 1
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0057 0.017 0.1134
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0076 0.0144
Loa Loa (eye worm) cysteine protease 0.083 0.4663 0.4663
Trichomonas vaginalis bromodomain-containing protein, putative 0.0171 0.0832 0.1769
Loa Loa (eye worm) cytochrome P450 family protein 0.0129 0.0588 0.0588
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0398 0.0836
Echinococcus granulosus cpg binding protein 0.0186 0.0918 0.0918
Plasmodium vivax unspecified product 0.0192 0.0955 0.2048
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0045 0.0097 0.0097
Entamoeba histolytica cysteine protease, putative 0.0451 0.2458 0.5215
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0139 0.0647 0.0647
Giardia lamblia Cysteine protease 0.0192 0.0955 0.2365
Loa Loa (eye worm) CYP4Cod1 0.0129 0.0588 0.0588
Onchocerca volvulus 0.0176 0.086 0.1825
Entamoeba histolytica cysteine proteinase, putative 0.0451 0.2458 0.5215
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0068 0.0128
Schistosoma mansoni hypothetical protein 0.0047 0.011 0.011
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.015 0.0709 0.0709
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0057 0.017 0.1134
Mycobacterium tuberculosis Probable dehydrogenase 0.0286 0.1499 0.5075
Echinococcus multilocularis thioredoxin glutathione reductase 0.0127 0.0575 0.0575
Schistosoma mansoni ap endonuclease 0.0077 0.0282 0.0282
Brugia malayi chromobox protein homolog 3 0.0038 0.0059 0.0059
Onchocerca volvulus 0.083 0.4663 1
Brugia malayi Pre-SET motif family protein 0.0034 0.0031 0.0031
Plasmodium vivax hypothetical protein, conserved 0.0082 0.0311 0.0666
Entamoeba histolytica cysteine protease, putative 0.0192 0.0955 0.1952
Brugia malayi cathepsin Z-like cysteine proteinase 0.0192 0.0955 0.0955
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0082 0.0311 0.0311
Onchocerca volvulus Huntingtin homolog 0.014 0.0652 0.1379
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0057 0.017 0.0293
Plasmodium vivax serine-repeat antigen (SERA) 0.0192 0.0955 0.2048
Loa Loa (eye worm) hypothetical protein 0.0082 0.0311 0.0311
Plasmodium falciparum importin beta, putative 0.003 0.0013 0.0029
Brugia malayi latrophilin 2 splice variant baaae 0.0181 0.0888 0.0888
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0025 0.0036
Loa Loa (eye worm) hypothetical protein 0.1747 1 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0051 0.0133 0.0267
Plasmodium falciparum cysteine proteinase falcipain 2b 0.083 0.4663 1
Loa Loa (eye worm) cytochrome P450 family protein 0.0129 0.0588 0.0588
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.083 0.4663 1
Brugia malayi Cathepsin L-like precursor 0.0571 0.316 0.316
Trypanosoma cruzi PAB1-binding protein , putative 0.005 0.0127 0.0127
Giardia lamblia Cysteine protease 0.0192 0.0955 0.2365
Onchocerca volvulus Cathepsin F homolog 0.083 0.4663 1
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.015 0.0709 0.1519
Giardia lamblia Cathepsin B precursor 0.0192 0.0955 0.2365
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0317 0.168 0.168
Toxoplasma gondii cathepsin CPL 0.083 0.4663 1
Brugia malayi glutathione reductase 0.0125 0.0565 0.0565
Plasmodium vivax glutathione reductase, putative 0.0125 0.0565 0.1212
Echinococcus granulosus mixed lineage leukemia protein mll 0.0045 0.0097 0.0097
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0318 0.1685 0.5742
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0084 0.0323 0.0323
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0192 0.0955 0.0955
Brugia malayi exodeoxyribonuclease III family protein 0.0077 0.0282 0.0282
Brugia malayi Papain family cysteine protease containing protein 0.0192 0.0955 0.0955
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0057 0.017 0.0293
Mycobacterium tuberculosis Probable oxidoreductase 0.0318 0.1685 0.5742
Trichomonas vaginalis D-aminoacylase, putative 0.0082 0.0311 0.0649
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0082 0.0311 0.3089
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0582 0.3223 0.3223
Entamoeba histolytica cysteine proteinase, putative 0.083 0.4663 1
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0041 0.0076 0.014
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0286 0.1499 0.8775
Plasmodium vivax hypothetical protein, conserved 0.0087 0.0344 0.0738
Giardia lamblia Hypothetical protein 0.0192 0.0955 0.2365
Trypanosoma cruzi PAB1-binding protein , putative 0.005 0.0127 0.0127
Trypanosoma brucei cytochrome P450, putative 0.0129 0.0588 0.1261
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0139 0.0647 0.0647
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.083 0.4663 0.4663
Entamoeba histolytica cysteine protease, putative 0.0451 0.2458 0.5215
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0571 0.316 0.677
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0286 0.15 0.15
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0043 0.0089 0.0089
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0139 0.0647 0.0647
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.083 0.4663 1
Schistosoma mansoni hypothetical protein 0.0325 0.1729 0.1729
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0057 0.017 0.1134
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0673 0.3752 0.8043
Loa Loa (eye worm) hypothetical protein 0.0258 0.1339 0.1339
Schistosoma mansoni hypothetical protein 0.0038 0.0056 0.0056
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0057 0.017 0.017
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0043 0.0089 0.019
Echinococcus multilocularis PHD finger protein rhinoceros 0.0087 0.0344 0.0344
Loa Loa (eye worm) hypothetical protein 0.0084 0.0323 0.0323
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0057 0.017 0.0293
Brugia malayi CXXC zinc finger family protein 0.0176 0.086 0.086
Mycobacterium tuberculosis Conserved protein 0.0082 0.0311 0.0799
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0192 0.0955 0.2048
Entamoeba histolytica acetyltransferase, GNAT family 0.0157 0.0749 0.1505
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0192 0.0955 0.2033
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0038 0.0059 0.0103
Plasmodium vivax vivapain-2 0.083 0.4663 1
Leishmania major cathepsin L-like protease 0.083 0.4663 1
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0043 0.0089 0.019
Echinococcus granulosus cathepsin L cysteine proteinase 0.083 0.4663 0.4663
Brugia malayi jmjC domain containing protein 0.0116 0.0509 0.0509
Trypanosoma cruzi cytochrome P450, putative 0.0129 0.0588 0.0588
Brugia malayi Cytochrome P450 family protein 0.0057 0.017 0.017
Giardia lamblia Kinase, PLK 0.0097 0.0398 0.0843
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.083 0.4663 1
Giardia lamblia Encystation-specific protease 0.0192 0.0955 0.2365
Loa Loa (eye worm) hypothetical protein 0.0264 0.1375 0.1375
Loa Loa (eye worm) acetyltransferase 0.0582 0.3223 0.3223
Schistosoma mansoni hypothetical protein 0.0868 0.4885 0.4885
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0043 0.0089 0.019
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0097 0.0398 0.0398
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0286 0.1499 0.5075
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.083 0.4663 1
Mycobacterium ulcerans aldehyde dehydrogenase 0.0063 0.0201 0.1566
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.1747 1 1
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0077 0.0282 0.2697
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0192 0.0955 0.2033
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0043 0.0089 0.019
Trypanosoma cruzi trypanothione reductase, putative 0.0043 0.0089 0.0089
Schistosoma mansoni cathepsin F (C01 family) 0.0571 0.316 0.316
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0192 0.0955 0.0955
Brugia malayi Thioredoxin reductase 0.0125 0.0565 0.0565
Brugia malayi Papain family cysteine protease containing protein 0.0192 0.0955 0.0955
Trypanosoma cruzi polo-like protein kinase, putative 0.0097 0.0398 0.0398
Trypanosoma cruzi cysteine peptidase, putative 0.083 0.4663 0.4663
Trypanosoma cruzi cysteine protease, putative 0.0451 0.2458 0.2458
Giardia lamblia Cathepsin B precursor 0.0673 0.3752 1
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0192 0.0955 0.1952
Leishmania major hypothetical protein, conserved 0.005 0.0127 0.0273
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.083 0.4663 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.083 0.4663 1
Echinococcus granulosus PHD finger protein rhinoceros 0.0087 0.0344 0.0344
Plasmodium vivax vivapain-3 0.0451 0.2458 0.5272
Brugia malayi cathepsin L precursor 0.0192 0.0955 0.0955
Brugia malayi beta-lactamase 0.0082 0.0311 0.0311
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0051 0.0133 0.0267
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0192 0.0955 0.2033
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0045 0.0095 0.0204
Echinococcus multilocularis cathepsin L cysteine protease 0.083 0.4663 0.4663
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0192 0.0955 0.2033
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.083 0.4663 1
Schistosoma mansoni serine/threonine protein kinase 0.0097 0.0398 0.0398
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0057 0.017 0.0293
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0084 0.0323 0.0323
Schistosoma mansoni importin beta-1 0.003 0.0013 0.0013
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0192 0.0955 0.2033
Leishmania major cathepsin L-like protease 0.083 0.4663 1
Schistosoma mansoni chromobox protein 0.0068 0.0233 0.0233
Plasmodium falciparum serine repeat antigen 5 0.0192 0.0955 0.2048
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0451 0.2458 0.2458
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0082 0.0311 0.0311
Echinococcus multilocularis lysine specific demethylase 5A 0.0106 0.0451 0.0451
Echinococcus granulosus cathepsin L 0.0451 0.2458 0.2458

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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