Detailed information for compound 1155812

Basic information

Technical information
  • TDR Targets ID: 1155812
  • Name: N-(2-aminoethyl)-2-(5-bromo-1H-indol-3-yl)-8- chloroquinoline-4-carboxamide
  • MW: 443.724 | Formula: C20H16BrClN4O
  • H donors: 3 H acceptors: 2 LogP: 3.63 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: NCCNC(=O)c1cc(nc2c1cccc2Cl)c1c[nH]c2c1cc(Br)cc2
  • InChi: 1S/C20H16BrClN4O/c21-11-4-5-17-13(8-11)15(10-25-17)18-9-14(20(27)24-7-6-23)12-2-1-3-16(22)19(12)26-18/h1-5,8-10,25H,6-7,23H2,(H,24,27)
  • InChiKey: DTTBCRPTECQRRR-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N-(2-aminoethyl)-2-(5-bromo-1H-indol-3-yl)-8-chloro-quinoline-4-carboxamide
  • N-(2-aminoethyl)-2-(5-bromo-1H-indol-3-yl)-8-chloro-4-quinolinecarboxamide
  • N-(2-aminoethyl)-2-(5-bromo-1H-indol-3-yl)-8-chloro-cinchoninamide

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni smad1 5 8 and 0.0018 0.0077 0.0095
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0443 0.142
Loa Loa (eye worm) angiotensin-converting enzyme family protein 0.06 0.67 0.8224
Trypanosoma cruzi serine peptidase, clan SC, family S9A-like protein, putative 0.0208 0.2232 0.381
Brugia malayi RNA, U transporter 1 0.0081 0.0789 0.0938
Mycobacterium tuberculosis Probable esterase LipL 0.0077 0.0746 0.0751
Onchocerca volvulus Deterin homolog 0.0161 0.1698 0.2829
Echinococcus granulosus 5'partial|ATP binding cassette sub family B 0.002 0.0101 0.012
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0021 0.0103 0.0103
Trypanosoma cruzi cysteine peptidase, putative 0.0032 0.0237 0.0361
Echinococcus granulosus neurogenic locus notch protein 0.0034 0.0255 0.0304
Loa Loa (eye worm) hypothetical protein 0.0303 0.3319 0.4057
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.019 0.2033 0.3465
Echinococcus granulosus protein C ets 2 0.0021 0.0111 0.0132
Entamoeba histolytica hypothetical protein 0.0018 0.0074 0.0312
Brugia malayi Cathepsin L-like cysteine proteinase 0.0066 0.0615 0.0725
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0021 0.0103 0.0245
Brugia malayi Thioredoxin family protein 0.0069 0.0658 0.0778
Trypanosoma brucei prolyl endopeptidase 0.0522 0.5813 1
Echinococcus multilocularis cysteine protease 0.0098 0.0984 0.0984
Echinococcus granulosus acylamino acid releasing enzyme 0.0055 0.0492 0.0586
Echinococcus multilocularis calpain 0.0022 0.0121 0.0121
Schistosoma mansoni gabp alpha 0.0147 0.1541 0.1893
Loa Loa (eye worm) prolyl oligopeptidase 0.0055 0.0492 0.0571
Brugia malayi Muscle positioning protein 4 0.0034 0.0255 0.0281
Entamoeba histolytica cysteine protease, putative 0.0018 0.0074 0.0312
Echinococcus granulosus Dipeptidyl peptidase 9 0.0055 0.0492 0.0586
Echinococcus granulosus protein jagged 1 0.0034 0.0255 0.0304
Echinococcus granulosus dipeptidyl aminopeptidaseprotein 0.0055 0.0492 0.0586
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0034 0.0255 0.0281
Trypanosoma cruzi hypothetical protein, conserved 0.0055 0.0492 0.0801
Echinococcus granulosus cathepsin l1 0.0066 0.0615 0.0734
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0019 0.0085 0.0059
Schistosoma mansoni ets 0.0021 0.0111 0.0136
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0131 0.034
Plasmodium vivax SET domain protein, putative 0.0034 0.0261 0.2047
Loa Loa (eye worm) hypothetical protein 0.0303 0.3319 0.4057
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0098 0.0984 0.3289
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0125 0.1293 0.1325
Echinococcus multilocularis Transglutaminase 0.0069 0.0658 0.0658
Schistosoma mansoni cathepsin F (C01 family) 0.0098 0.0984 0.1209
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0019 0.0085 0.0097
Brugia malayi EGF-like domain containing protein 0.0034 0.0255 0.0281
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0018 0.0077 0.0077
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.004 0.032 0.2697
Loa Loa (eye worm) hypothetical protein 0.0021 0.0103 0.0092
Entamoeba histolytica prolyl oligopeptidase family protein 0.0055 0.0492 0.4758
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0055 0.0492 0.1588
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0019 0.0085 0.0097
Echinococcus multilocularis slit 2 protein 0.0034 0.0255 0.0255
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0098 0.0984 0.3289
Brugia malayi cathepsin Z-like cysteine proteinase 0.0018 0.0074 0.0058
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0054 0.0481 0.0559
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0098 0.0984 0.3289
Echinococcus granulosus beta LACTamase domain containing family member 0.0077 0.0746 0.0889
Echinococcus multilocularis hypothetical protein 0.0022 0.0121 0.0121
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0051 0.0443 0.0717
Schistosoma mansoni hypothetical protein 0.0021 0.0111 0.0136
Entamoeba histolytica cysteine protease, putative 0.0051 0.0443 0.424
Schistosoma mansoni hypothetical protein 0.0069 0.0658 0.0809
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0021 0.0103 0.0103
Brugia malayi Ets-domain containing protein 0.0147 0.1541 0.1865
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0022 0.0121 0.0159
Plasmodium falciparum cysteine proteinase falcipain 3 0.0098 0.0984 1
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0161 0.1698 0.2059
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0443 0.142
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.019 0.2033 0.3465
Giardia lamblia NADH oxidase lateral transfer candidate 0.0019 0.0085 0.0164
Echinococcus multilocularis cathepsin L 0.0018 0.0074 0.0074
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0019 0.0085 0.0116
Loa Loa (eye worm) hypothetical protein 0.0028 0.0192 0.0201
Entamoeba histolytica cysteine protease, putative 0.0018 0.0074 0.0312
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0019 0.0085 0.0097
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0022 0.0121 0.0159
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0021 0.0103 0.0245
Echinococcus granulosus neurogenic locus notch protein 4 0.0034 0.0255 0.0304
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0022 0.0121 0.0159
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0021 0.0103 0.0245
Leishmania major hypothetical protein, conserved 0.0077 0.0746 0.1239
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0074 0.0091
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0021 0.0103 0.0129
Echinococcus multilocularis flap endonuclease 1 0.0026 0.0164 0.0164
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0077 0.0746 0.0884
Loa Loa (eye worm) blistered cuticle protein 3 0.0303 0.3319 0.4057
Trypanosoma cruzi trypanothione reductase, putative 0.0055 0.0493 0.0803
Loa Loa (eye worm) hypothetical protein 0.0077 0.0746 0.0884
Brugia malayi hypothetical protein 0.0017 0.0058 0.0037
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0051 0.0443 0.0545
Leishmania major cytochrome p450-like protein 0.0023 0.0127 0.017
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0077 0.0746 0.0751
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0021 0.0103 0.0103
Trypanosoma brucei hypothetical protein, conserved 0.0077 0.0746 0.1239
Mycobacterium tuberculosis Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. 0.0075 0.0718 0.0722
Trichomonas vaginalis Clan SC, family S9, acylaminoacyl-peptidase-like serine peptidase 0.0055 0.0492 0.1588
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0098 0.0984 0.0984
Echinococcus granulosus ETS domain containing protein Elk 1 0.0021 0.0111 0.0132
Plasmodium vivax calpain, putative 0.0022 0.0121 0.0512
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0162 0.0961
Echinococcus multilocularis thioredoxin glutathione reductase 0.0055 0.0493 0.0493
Entamoeba histolytica cysteine protease, putative 0.0051 0.0443 0.424
Brugia malayi beta-lactamase family protein 0.0077 0.0746 0.0885
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0074 0.0145
Brugia malayi Cadherin domain containing protein 0.0034 0.0255 0.0281
Brugia malayi EGF-like domain containing protein 0.0034 0.0255 0.0281
Echinococcus multilocularis neural cadherin 0.0034 0.0255 0.0255
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0033 0.0239 0.0285
Echinococcus granulosus cathepsin L 0.0051 0.0443 0.0528
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0304 0.3323 0.4062
Entamoeba histolytica P-glycoprotein-2 0.0021 0.0103 0.0621
Echinococcus granulosus calpain 5 0.0022 0.0121 0.0144
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0107 0.0135
Brugia malayi fibroinase precursor 0.0018 0.0074 0.0058
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.0261 0.032
Echinococcus granulosus cathepsin b 0.0018 0.0074 0.0089
Echinococcus granulosus neural cadherin 0.0034 0.0255 0.0304
Schistosoma mansoni hypothetical protein 0.0054 0.0481 0.0591
Echinococcus granulosus calpain A 0.0061 0.0568 0.0677
Echinococcus granulosus GPCR family 2 0.0054 0.0481 0.0574
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0018 0.0074 0.0091
Brugia malayi CXXC zinc finger family protein 0.0031 0.0224 0.0242
Brugia malayi latrophilin 2 splice variant baaae 0.0116 0.1192 0.1436
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.0107 0.0135
Mycobacterium tuberculosis Conserved protein 0.0069 0.0658 0.066
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0066 0.0615 0.2014
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0019 0.0085 0.0097
Loa Loa (eye worm) hypothetical protein 0.0034 0.0255 0.0279
Loa Loa (eye worm) hypothetical protein 0.0034 0.0261 0.0286
Plasmodium vivax ataxin-2 like protein, putative 0.0026 0.0162 0.0961
Toxoplasma gondii proteasome subunit beta type, putative 0.0075 0.0718 0.1191
Trypanosoma cruzi prolyl endopeptidase 0.0522 0.5813 1
Brugia malayi EGF-like domain containing protein 0.0034 0.0255 0.0281
Onchocerca volvulus 0.0034 0.0255 0.0315
Brugia malayi cathepsin Z-like cysteine proteinase 0.0018 0.0074 0.0058
Onchocerca volvulus Neurogenic locus notch homolog 0.0034 0.0255 0.0315
Schistosoma mansoni cellular tumor antigen P53 0.011 0.1115 0.137
Loa Loa (eye worm) calpain 5 0.0016 0.0045 0.002
Brugia malayi Cathepsin L-like precursor 0.0098 0.0984 0.1179
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0192 0.0282
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0021 0.0103 0.0245
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0098 0.0984 0.3289
Echinococcus granulosus protein jagged 1 0.0034 0.0255 0.0304
Mycobacterium tuberculosis Long conserved protein 0.0069 0.0658 0.066
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0021 0.0103 0.0245
Mycobacterium tuberculosis Conserved protein 0.0077 0.0746 0.0751
Echinococcus granulosus neurogenic locus protein delta 0.0034 0.0255 0.0304
Schistosoma mansoni smad 0.0018 0.0077 0.0095
Brugia malayi Cadherin domain containing protein 0.0034 0.0255 0.0281
Plasmodium vivax vivapain-1 0.0051 0.0443 0.4054
Schistosoma mansoni calpain (C02 family) 0.0022 0.0121 0.0149
Entamoeba histolytica cysteine proteinase, putative 0.0098 0.0984 1
Brugia malayi Cathepsin L-like precursor 0.0098 0.0984 0.1179
Leishmania major GTP-binding protein, putative 0.0021 0.0107 0.0135
Schistosoma mansoni calpain C (C02 family) 0.0022 0.0121 0.0149
Schistosoma mansoni notch 0.0034 0.0255 0.0313
Loa Loa (eye worm) hypothetical protein 0.002 0.0101 0.0089
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.0061 0.0568 0.0677
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0019 0.0085 0.0116
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0131 0.034
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0022 0.0121 0.0159
Brugia malayi Delta serrate ligand family protein 0.0034 0.0255 0.0281
Echinococcus multilocularis acylamino acid releasing enzyme 0.0055 0.0492 0.0492
Loa Loa (eye worm) hypothetical protein 0.0034 0.0255 0.0279
Mycobacterium leprae proteasome (beta subunit) PrcB 0.0075 0.0718 0.0722
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.004 0.032 0.2697
Loa Loa (eye worm) calpain family protein 1 0.0043 0.0361 0.041
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0019 0.0085 0.0097
Loa Loa (eye worm) CYP4Cod1 0.0023 0.0127 0.0121
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0021 0.0103 0.0123
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0068 0.0637 0.0782
Echinococcus granulosus protein jagged 2 0.0034 0.0255 0.0304
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0095 0.0949 0.1136
Echinococcus granulosus histone lysine methyltransferase setb 0.0034 0.0261 0.0311
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0061 0.0568 0.0698
Mycobacterium ulcerans beta-lactamase 0.0077 0.0746 0.0751
Brugia malayi MH1 domain containing protein 0.0018 0.0077 0.0061
Schistosoma mansoni dipeptidyl-peptidase 9 (S09 family) 0.0055 0.0492 0.0604
Echinococcus granulosus delta-like protein 1 0.0034 0.0255 0.0304
Schistosoma mansoni importin beta-1 0.0028 0.0192 0.0236
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0021 0.0111 0.0101
Entamoeba histolytica cysteine protease, putative 0.0051 0.0443 0.424
Loa Loa (eye worm) hypothetical protein 0.0034 0.0255 0.0279
Trypanosoma brucei prolyl oligopeptidase, putative 0.0208 0.2232 0.381
Loa Loa (eye worm) hypothetical protein 0.0055 0.0492 0.0571
Echinococcus granulosus cytochrome P450 2K1 0.0014 0.0029 0.0034
Entamoeba histolytica P-glycoprotein 5, putative 0.0021 0.0103 0.0621
Toxoplasma gondii exonuclease III APE 0.004 0.032 0.0503
Plasmodium vivax unspecified product 0.0051 0.0443 0.4054
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0019 0.0085 0.0097
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0054 0.0481 0.0574
Entamoeba histolytica cysteine protease, putative 0.0051 0.0443 0.424
Entamoeba histolytica proteasome subunit beta type 5 precursor, putative 0.0075 0.0718 0.7162
Loa Loa (eye worm) hypothetical protein 0.0066 0.0615 0.0723
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0077 0.0746 0.0916
Mycobacterium tuberculosis Probable peptidase 0.0208 0.2232 0.231
Mycobacterium ulcerans putative transglutaminase-like protein 0.0069 0.0658 0.066
Loa Loa (eye worm) hypothetical protein 0.0034 0.0255 0.0279
Trichomonas vaginalis ap endonuclease, putative 0.004 0.032 0.0993
Loa Loa (eye worm) hypothetical protein 0.0303 0.3319 0.4057
Onchocerca volvulus 0.0037 0.0285 0.0368
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0098 0.0984 0.3289
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0021 0.0103 0.0245
Echinococcus multilocularis calpain family protein 1, d 0.0043 0.0361 0.0361
Trichomonas vaginalis ABC transporter, putative 0.0021 0.0103 0.0245
Schistosoma mansoni hypothetical protein 0.0116 0.1192 0.1465
Brugia malayi Calcitonin receptor-like protein seb-1 0.017 0.1805 0.2191
Entamoeba histolytica Flap nuclease, putative 0.0026 0.0164 0.1266
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.004 0.032 0.0503
Trypanosoma brucei calpain-like protein, putative 0.0022 0.0121 0.0159
Trypanosoma cruzi cysteine peptidase, putative 0.019 0.2033 0.3465
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0131 0.0176
Loa Loa (eye worm) hypothetical protein 0.0077 0.0746 0.0884
Entamoeba histolytica cysteine proteinase, putative 0.0051 0.0443 0.424
Echinococcus granulosus Smad4 0.0018 0.0077 0.0092
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.004 0.032 0.0503
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0022 0.0121 0.0159
Echinococcus multilocularis fibropellin Ia 0.0034 0.0255 0.0255
Onchocerca volvulus 0.0034 0.0255 0.0315
Brugia malayi MH2 domain containing protein 0.0018 0.0077 0.0061
Toxoplasma gondii histone lysine methyltransferase SET1 0.006 0.0556 0.0912
Echinococcus multilocularis multidrug resistance protein 1 0.0021 0.0103 0.0103
Plasmodium vivax vivapain-2 0.0098 0.0984 1
Echinococcus granulosus multidrug resistance protein 1 0.0021 0.0103 0.0123
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0019 0.0085 0.0097
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0061 0.0568 0.0698
Entamoeba histolytica cysteine protease, putative 0.0051 0.0443 0.424
Trypanosoma cruzi cruzipain precursor, putative 0.0032 0.0237 0.0361
Echinococcus granulosus multidrug resistance protein 1 0.0021 0.0103 0.0123
Trichomonas vaginalis flap endonuclease-1, putative 0.0026 0.0164 0.0454
Schistosoma mansoni cpg binding protein 0.0033 0.0244 0.03
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0098 0.0984 1
Trichomonas vaginalis D-aminoacylase, putative 0.0077 0.0746 0.2465
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0098 0.0984 0.3289
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0139 0.1452 0.1492
Brugia malayi Cathepsin L-like precursor 0.0032 0.0237 0.0259
Schistosoma mansoni notch 0.0034 0.0255 0.0313
Brugia malayi Papain family cysteine protease containing protein 0.0051 0.0443 0.0513
Loa Loa (eye worm) D-ets-2 protein 0.0021 0.0111 0.0101
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0021 0.0103 0.0123
Mycobacterium leprae probable proteasome (alpha subunit) PrcA 0.0852 0.957 1
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0054 0.0481 0.0481
Echinococcus multilocularis ETS transcription factor Elf 2 0.0021 0.0111 0.0111
Brugia malayi multidrug resistance protein 3 0.0021 0.0103 0.0094
Entamoeba histolytica P-glyco protein 6, putative 0.0021 0.0103 0.0621
Entamoeba histolytica Ran family GTPase 0.0021 0.0107 0.0656
Loa Loa (eye worm) hypothetical protein 0.0303 0.3319 0.4057
Trypanosoma brucei oligopeptidase b 0.0208 0.2232 0.381
Brugia malayi Fli-1 protein 0.0446 0.4945 0.6062
Loa Loa (eye worm) hypothetical protein 0.0034 0.0255 0.0279
Brugia malayi Proteasome A-type and B-type family protein 0.0075 0.0718 0.0851
Leishmania major dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B 0.0055 0.0492 0.0801
Trypanosoma cruzi cruzipain precursor, putative 0.019 0.2033 0.3465
Toxoplasma gondii cathepsin CPC2 0.0018 0.0074 0.0079
Schistosoma mansoni multidrug resistance protein 0.0021 0.0103 0.0127
Echinococcus multilocularis 0.0014 0.0029 0.0029
Leishmania major hypothetical protein, conserved 0.0026 0.0162 0.023
Schistosoma mansoni multidrug resistance protein 0.0021 0.0103 0.0127
Schistosoma mansoni ap endonuclease 0.004 0.032 0.0393
Entamoeba histolytica cysteine protease, putative 0.0018 0.0074 0.0312
Brugia malayi Cytochrome P450 family protein 0.0023 0.0127 0.0123
Echinococcus granulosus calpain A 0.0022 0.0121 0.0144
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.019 0.2033 0.3465
Brugia malayi beta-lactamase 0.0077 0.0746 0.0885
Mycobacterium tuberculosis Probable lipase LipD 0.0077 0.0746 0.0751
Schistosoma mansoni notch 0.0034 0.0255 0.0313
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0125 0.1293 0.1325
Schistosoma mansoni ap endonuclease 0.004 0.032 0.0393
Onchocerca volvulus 0.0021 0.0103 0.0051
Echinococcus multilocularis snurportin 1 0.0304 0.3323 0.3323
Onchocerca volvulus Slit protein homolog 0.0034 0.0255 0.0315
Mycobacterium tuberculosis Conserved protein 0.0077 0.0746 0.0751
Loa Loa (eye worm) hypothetical protein 0.0066 0.0615 0.0723
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.0018 0.0074 0.0091
Onchocerca volvulus Cathepsin L homolog 0.0098 0.0984 0.1586
Echinococcus multilocularis neurogenic locus notch protein 4 0.0034 0.0255 0.0255
Trichomonas vaginalis abcb9, putative 0.0021 0.0103 0.0245
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0021 0.0103 0.0245
Loa Loa (eye worm) MH1 domain-containing protein 0.0018 0.0077 0.006
Plasmodium vivax vivapain-3 0.0051 0.0443 0.4054
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0098 0.0984 0.3289
Onchocerca volvulus 0.0077 0.0746 0.117
Brugia malayi Ets-domain containing protein 0.0021 0.0111 0.0103
Schistosoma mansoni smad1 5 8 and 0.0018 0.0077 0.0095
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0098 0.0984 0.3289
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0021 0.0103 0.0245
Giardia lamblia High cysteine protein 0.0034 0.0255 0.2809
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0522 0.5813 0.7141
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0018 0.0074 0.0091
Entamoeba histolytica cysteine protease, putative 0.0051 0.0443 0.424
Schistosoma mansoni cathepsin C 0.0018 0.0074 0.0091
Loa Loa (eye worm) hypothetical protein 0.0077 0.0746 0.0884
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0019 0.0085 0.0116
Echinococcus granulosus multidrug resistance protein 1 0.0014 0.0032 0.0039
Leishmania major cathepsin L-like protease 0.0098 0.0984 0.1652
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0074 0.0091
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0098 0.0984 0.3289
Giardia lamblia Alanyl dipeptidyl peptidase 0.0055 0.0492 0.649
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.019 0.2033 0.3465
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0021 0.0103 0.0245
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.019 0.2033 0.3465
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0074 0.0091
Mycobacterium ulcerans lipase LipD 0.0077 0.0746 0.0751
Brugia malayi cathepsin B-like cysteine proteinase 0.0018 0.0074 0.0058
Entamoeba histolytica prolyl oligopeptidase family protein 0.0055 0.0492 0.4758
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0098 0.0984 0.0984
Loa Loa (eye worm) hypothetical protein 0.0052 0.0462 0.0534
Loa Loa (eye worm) hypothetical protein 0.0034 0.0255 0.0279
Trichomonas vaginalis esterase, putative 0.0077 0.0746 0.2465
Entamoeba histolytica prolyl oligopeptidase family protein 0.0055 0.0492 0.4758
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0077 0.0746 0.0916
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0098 0.0984 0.1178
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.004 0.032 0.0503
Schistosoma mansoni peroxidasin 0.0303 0.3319 0.4078
Entamoeba histolytica P-glycoprotein-1 0.0021 0.0103 0.0621
Echinococcus multilocularis fat cadherin tumor suppressor 0.0034 0.0255 0.0255
Loa Loa (eye worm) hypothetical protein 0.0018 0.0074 0.0056
Plasmodium falciparum peptidase, putative 0.0055 0.0492 0.4589
Brugia malayi calpain 7 0.0022 0.0121 0.0115
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0095 0.0949 0.1166
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0018 0.0074 0.0312
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0019 0.0085 0.0059
Entamoeba histolytica hypothetical protein 0.0023 0.0131 0.0914
Entamoeba histolytica cysteine protease, putative 0.0051 0.0443 0.424
Schistosoma mansoni subfamily S9B unassigned peptidase (S09 family) 0.0055 0.0492 0.0604
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0022 0.0121 0.0159
Schistosoma mansoni peroxidasin 0.0303 0.3319 0.4078
Onchocerca volvulus 0.0031 0.0224 0.0261
Mycobacterium tuberculosis Probable reductase 0.0125 0.1293 0.1325
Echinococcus multilocularis geminin 0.0373 0.4118 0.4118
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.0107 0.0135
Loa Loa (eye worm) hypothetical protein 0.0034 0.0255 0.0279
Brugia malayi prolyl oligopeptidase family protein 0.0055 0.0492 0.0573
Loa Loa (eye worm) hypothetical protein 0.0032 0.0237 0.0257
Mycobacterium ulcerans hypothetical protein 0.0069 0.0658 0.066
Echinococcus granulosus fibropellin Ia 0.0034 0.0255 0.0304
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0051 0.0443 0.0545
Loa Loa (eye worm) hypothetical protein 0.0034 0.0255 0.0279
Echinococcus multilocularis gamma secretase subunit aph 1 0.0727 0.814 0.814
Trichomonas vaginalis penicillin-binding protein, putative 0.0077 0.0746 0.2465
Brugia malayi calpain family protein 1 0.0059 0.0538 0.0629
Toxoplasma gondii hypothetical protein 0.0055 0.0492 0.0801
Trypanosoma brucei Aph-1 protein, putative 0.0283 0.3091 0.5295
Mycobacterium leprae Conserved hypothetical protein 0.0069 0.0658 0.066
Brugia malayi notch-like transmembrane receptor 0.0034 0.0255 0.0281
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0192 0.0282
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0019 0.0085 0.0097
Schistosoma mansoni hypothetical protein 0.0034 0.0255 0.0313
Mycobacterium ulcerans proteasome PrcB 0.0075 0.0718 0.0722
Leishmania major cathepsin L-like protease 0.019 0.2033 0.3465
Loa Loa (eye worm) DNA-binding protein D-ETS-3 0.0021 0.0111 0.0101
Mycobacterium tuberculosis Conserved hypothetical protein 0.0069 0.0658 0.066
Plasmodium falciparum importin beta, putative 0.0028 0.0192 0.1294
Mycobacterium tuberculosis Probable oxidoreductase 0.0139 0.1452 0.1492
Brugia malayi glutathione reductase 0.0055 0.0493 0.0574
Loa Loa (eye worm) hypothetical protein 0.0303 0.3319 0.4057
Loa Loa (eye worm) hypothetical protein 0.0021 0.0111 0.0101
Trypanosoma brucei PAB1-binding protein , putative 0.0026 0.0162 0.023
Onchocerca volvulus 0.0161 0.1698 0.2829
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0021 0.0103 0.0245
Loa Loa (eye worm) gamma-secretase subunit aph-1 0.0727 0.814 1
Onchocerca volvulus Cathepsin F homolog 0.0098 0.0984 0.1586
Brugia malayi hypothetical protein 0.0026 0.0162 0.0166
Schistosoma mansoni Smad4 0.0018 0.0077 0.0095
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.0107 0.0355
Echinococcus granulosus protein jagged 2 0.0034 0.0255 0.0304
Echinococcus granulosus gamma secretase subunit aph 1 0.0727 0.814 0.9704
Schistosoma mansoni septate junction protein 0.0034 0.0255 0.0313
Trypanosoma cruzi dipeptidyl-peptidase 8-like serine peptidase 0.0055 0.0492 0.0801
Echinococcus multilocularis protein C ets 2 0.0021 0.0111 0.0111
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0034 0.0261 0.0401
Onchocerca volvulus 0.011 0.1115 0.1814
Loa Loa (eye worm) hypothetical protein 0.0018 0.0074 0.0056
Mycobacterium ulcerans hypothetical protein 0.0069 0.0658 0.066
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0075 0.0718 0.0849
Brugia malayi Papain family cysteine protease containing protein 0.0018 0.0074 0.0058
Schistosoma mansoni cpg binding protein 0.0033 0.0244 0.03
Brugia malayi cathepsin L-like precursor 0.0066 0.0615 0.0725
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0095 0.0949 0.0949
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0098 0.0984 0.3289
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0098 0.0984 1
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0022 0.0121 0.0159
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0098 0.0984 0.3289
Trichomonas vaginalis peptide N-glycanase, putative 0.0069 0.0658 0.2163
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0098 0.0984 0.3289
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0074 0.0145
Leishmania major cathepsin L-like protease 0.0098 0.0984 0.1652
Brugia malayi Flap endonuclease-1 0.0026 0.0164 0.0168
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0098 0.0984 0.1178
Onchocerca volvulus 0.0077 0.0746 0.117
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0034 0.0261 0.0261
Loa Loa (eye worm) hypothetical protein 0.0018 0.0074 0.0056
Mycobacterium ulcerans protease II (oligopeptidase B), PtrB 0.0208 0.2232 0.231
Plasmodium vivax vivapain-2 0.0098 0.0984 1
Plasmodium falciparum cysteine proteinase falcipain 1 0.0051 0.0443 0.4054
Brugia malayi prolyl oligopeptidase family protein 0.0522 0.5813 0.7131
Echinococcus granulosus snurportin 1 0.0304 0.3323 0.3962
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.019 0.2033 0.3465
Trypanosoma cruzi cysteine peptidase, putative 0.0051 0.0443 0.0717
Schistosoma mansoni hypothetical protein 0.0034 0.0255 0.0313
Toxoplasma gondii cathepsin B 0.0018 0.0074 0.0079
Echinococcus granulosus ETS transcription factor Elf 5 0.0021 0.0111 0.0132
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0074 0.0091
Schistosoma mansoni hypothetical protein 0.0034 0.0255 0.0313
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0074 0.0145
Mycobacterium tuberculosis Conserved protein 0.0077 0.0746 0.0751
Plasmodium falciparum thioredoxin reductase 0.0055 0.0493 0.4602
Loa Loa (eye worm) calpain 0.0022 0.0121 0.0114
Brugia malayi prolyl oligopeptidase family protein 0.0055 0.0492 0.0573
Giardia lamblia Flap structure-specific endonuclease 0.0026 0.0164 0.1393
Onchocerca volvulus 0.0098 0.0984 0.1586
Echinococcus granulosus baculoviral IAP repeat containing protein 0.0161 0.1698 0.2024
Schistosoma mansoni hypothetical protein 0.0014 0.0029 0.0035
Trypanosoma brucei calpain-like protein, putative 0.0022 0.0121 0.0159
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0074 0.0145
Schistosoma mansoni inhibitor of apoptosis protein 0.0161 0.1698 0.2086
Brugia malayi Calcium binding EGF domain containing protein 0.0034 0.0255 0.0281
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0021 0.0103 0.0245
Onchocerca volvulus 0.0098 0.0984 0.1586
Loa Loa (eye worm) hypothetical protein 0.0034 0.0255 0.0279
Toxoplasma gondii ABC1 family protein 0.0077 0.0746 0.1239
Loa Loa (eye worm) calpain family protein 1 0.0059 0.0538 0.0628
Echinococcus multilocularis cathepsin b 0.0018 0.0074 0.0074
Loa Loa (eye worm) hypothetical protein 0.0077 0.0746 0.0884
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0074 0.0145
Echinococcus multilocularis calpain A 0.0061 0.0568 0.0568
Echinococcus granulosus proteasome prosome macropain 0.0075 0.0718 0.0856
Schistosoma mansoni cell polarity protein 0.0034 0.0255 0.0313
Brugia malayi Animal haem peroxidase family protein 0.0303 0.3319 0.4058
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0051 0.0443 0.0545
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0018 0.0074 0.0056
Toxoplasma gondii dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein 0.0055 0.0492 0.0801
Schistosoma mansoni multidrug resistance protein 0.0021 0.0103 0.0127
Echinococcus multilocularis baculoviral IAP repeat containing protein 0.0161 0.1698 0.1698
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0021 0.0103 0.0245
Loa Loa (eye worm) hypothetical protein 0.0034 0.0255 0.0279
Loa Loa (eye worm) hypothetical protein 0.0303 0.3319 0.4057
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.019 0.2033 0.3465
Mycobacterium tuberculosis Probable transmembrane multidrug efflux pump 0.0021 0.0103 0.0078
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0032 0.0237 0.0259
Brugia malayi Animal haem peroxidase family protein 0.0303 0.3319 0.4058
Loa Loa (eye worm) cytochrome P450 family protein 0.0023 0.0127 0.0121
Mycobacterium tuberculosis Probable protease II PtrBb [second part] (oligopeptidase B) 0.0208 0.2232 0.231
Brugia malayi hypothetical protein 0.0303 0.3319 0.4058
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0019 0.0085 0.0085
Brugia malayi Papain family cysteine protease containing protein 0.0098 0.0984 0.1179
Plasmodium vivax hypothetical protein, conserved 0.0077 0.0746 0.7377
Echinococcus multilocularis peroxidasin 0.0303 0.3319 0.3319
Trichomonas vaginalis ran, putative 0.0021 0.0107 0.0256
Echinococcus granulosus calpain 7 C02 family 0.0022 0.0121 0.0144
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0074 0.0145
Schistosoma mansoni hypothetical protein 0.0034 0.0255 0.0313
Trypanosoma brucei calpain-like protein, putative 0.0022 0.0121 0.0159
Schistosoma mansoni hypothetical protein 0.0021 0.0111 0.0136
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0026 0.0164 0.0234
Schistosoma mansoni inhibitor of apoptosis (iap) domain family member 0.0161 0.1698 0.2086
Schistosoma mansoni notch 0.0034 0.0255 0.0313
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0139 0.1452 0.1492
Echinococcus granulosus notch 0.0034 0.0255 0.0304
Leishmania major prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative 0.0522 0.5813 1
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0026 0.0164 0.0234
Schistosoma mansoni flap endonuclease-1 0.0023 0.0136 0.0167
Entamoeba histolytica P-glycoprotein-2 0.0021 0.0103 0.0621
Chlamydia trachomatis ABC transporter ATP binding protein/permease 0.0021 0.0103 1
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0018 0.0074 0.0091
Loa Loa (eye worm) MH2 domain-containing protein 0.0018 0.0077 0.006
Loa Loa (eye worm) cysteine protease 0.0098 0.0984 0.1178
Loa Loa (eye worm) fli-1 protein 0.0446 0.4945 0.6061
Schistosoma mansoni smad1 5 8 and 0.0018 0.0077 0.0095
Echinococcus granulosus ewsr:fli fusion protein type 0.0021 0.0111 0.0132
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.004 0.032 0.032
Schistosoma mansoni cathepsin F (C01 family) 0.0066 0.0615 0.0756
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0095 0.0949 0.1166
Toxoplasma gondii HEAT repeat-containing protein 0.0028 0.0192 0.0282
Loa Loa (eye worm) hypothetical protein 0.0034 0.0255 0.0279
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0018 0.0077 0.0095
Entamoeba histolytica cysteine proteinase, putative 0.0098 0.0984 1
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0054 0.0481 0.0481
Schistosoma mansoni calpain-7 (C02 family) 0.0026 0.0159 0.0195
Trypanosoma cruzi cytochrome P450, putative 0.0023 0.0127 0.017
Trypanosoma cruzi trypanothione reductase, putative 0.0019 0.0085 0.0097
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0074 0.0091
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0018 0.0074 0.0056
Loa Loa (eye worm) hypothetical protein 0.0098 0.0984 0.1178
Schistosoma mansoni hypothetical protein 0.0034 0.0255 0.0313
Mycobacterium tuberculosis Proteasome alpha subunit PrcA; assembles with beta subunit PrcB. 0.0852 0.957 1
Echinococcus multilocularis notch 0.0034 0.0255 0.0255
Onchocerca volvulus 0.0066 0.0615 0.0943
Mycobacterium ulcerans proteasome PrcA 0.0852 0.957 1
Trichomonas vaginalis D-aminoacylase, putative 0.0077 0.0746 0.2465
Onchocerca volvulus 0.0034 0.0255 0.0315
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0066 0.0615 0.2014
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0019 0.0085 0.0104
Echinococcus multilocularis ewsr:fli fusion protein type 0.0021 0.0111 0.0111
Echinococcus multilocularis GA binding protein alpha chain 0.0147 0.1541 0.1541
Mycobacterium tuberculosis Probable lipase LipE 0.0077 0.0746 0.0751
Loa Loa (eye worm) flap endonuclease-1 0.0026 0.0164 0.0167
Brugia malayi prolyl oligopeptidase family protein 0.0055 0.0492 0.0573
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.004 0.032 0.0305
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0095 0.0949 0.1134
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0019 0.0085 0.0059
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0125 0.1293 0.1325
Trichomonas vaginalis conserved hypothetical protein 0.0055 0.0492 0.1588
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0055 0.0493 0.0487
Mycobacterium tuberculosis Probable protease II PtrBa [first part] (oligopeptidase B) 0.0468 0.5189 0.5409
Echinococcus multilocularis calpain 5 0.0022 0.0121 0.0121
Echinococcus granulosus neurogenic locus notch protein 0.0034 0.0255 0.0304
Loa Loa (eye worm) animal heme peroxidase 0.0303 0.3319 0.4057
Echinococcus multilocularis dipeptidyl aminopeptidaseprotein 0.0055 0.0492 0.0492
Toxoplasma gondii thioredoxin reductase 0.0055 0.0493 0.0803
Echinococcus multilocularis proteasome (prosome, macropain) 0.0075 0.0718 0.0718
Loa Loa (eye worm) glutathione reductase 0.0055 0.0493 0.0572
Loa Loa (eye worm) cytochrome P450 family protein 0.0023 0.0127 0.0121
Mycobacterium tuberculosis Probable dehydrogenase 0.0125 0.1293 0.1325
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0059 0.0538 0.0661
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0077 0.0746 0.0751
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0019 0.0085 0.0097
Trypanosoma cruzi cysteine protease, putative 0.0051 0.0443 0.0717
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0074 0.0091
Trichomonas vaginalis ABC transporter, putative 0.0021 0.0103 0.0245
Loa Loa (eye worm) hypothetical protein 0.0055 0.0492 0.0571
Loa Loa (eye worm) hypothetical protein 0.0034 0.0255 0.0279
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0162 0.023
Brugia malayi MH1 domain containing protein 0.0018 0.0077 0.0061
Trypanosoma brucei calpain-like protein, putative 0.0022 0.0121 0.0159
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0125 0.1293 0.1325
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0019 0.0085 0.0097
Brugia malayi Pre-SET motif family protein 0.0236 0.2556 0.3117
Loa Loa (eye worm) ets-domain-containing protein 0.0021 0.0111 0.0101
Onchocerca volvulus 0.0034 0.0255 0.0315
Giardia lamblia Alanyl dipeptidyl peptidase 0.0055 0.0492 0.649
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0074 0.0091
Loa Loa (eye worm) fibroinase 0.0098 0.0984 0.1178
Echinococcus granulosus multidrug resistance protein 1 0.0014 0.0032 0.0039
Trypanosoma cruzi hypothetical protein, conserved 0.0077 0.0746 0.1239
Echinococcus multilocularis multidrug resistance protein 1 0.0021 0.0103 0.0103
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0021 0.0103 0.0245
Loa Loa (eye worm) pigment dispersing factor receptor c 0.017 0.1805 0.219
Echinococcus multilocularis ETS transcription factor Elf 1 0.0021 0.0111 0.0111
Toxoplasma gondii LsmAD domain-containing protein 0.0026 0.0162 0.023
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0074 0.0145
Toxoplasma gondii cathepsin CPC1 0.0018 0.0074 0.0079
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.004 0.032 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0098 0.0984 0.3289
Echinococcus multilocularis GPCR, family 2 0.0054 0.0481 0.0481
Echinococcus granulosus smad 0.0018 0.0077 0.0092
Schistosoma mansoni hypothetical protein 0.0054 0.0481 0.0591
Trichomonas vaginalis ap endonuclease, putative 0.004 0.032 0.0993
Echinococcus multilocularis protein jagged 1 0.0034 0.0255 0.0255
Plasmodium vivax hypothetical protein, conserved 0.0055 0.0492 0.4589
Loa Loa (eye worm) ATP-binding cassette sub-family B member 2 0.0021 0.0103 0.0092
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0098 0.0984 0.3289
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.0061 0.0568 0.0568
Loa Loa (eye worm) hypothetical protein 0.0522 0.5813 0.7131
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0021 0.0103 0.0103
Loa Loa (eye worm) multidrug resistance protein 3 0.0021 0.0103 0.0092
Leishmania major cathepsin L-like protease 0.019 0.2033 0.3465
Trypanosoma cruzi Aph-1 protein, putative 0.0283 0.3091 0.5295
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0107 0.0096
Echinococcus multilocularis Smad4 0.0018 0.0077 0.0077
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0018 0.0074 0.0145
Trypanosoma cruzi serine peptidase, Clan SC, Family S9B 0.0055 0.0492 0.0801
Onchocerca volvulus 0.0303 0.3319 0.5655
Plasmodium falciparum flap endonuclease 1 0.0026 0.0164 0.0985
Brugia malayi Thioredoxin reductase 0.0055 0.0493 0.0574
Brugia malayi Cathepsin L-like precursor 0.0098 0.0984 0.1179
Plasmodium vivax glutathione reductase, putative 0.0055 0.0493 0.4602
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0075 0.0718 0.1191
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0021 0.0103 0.0245
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.019 0.2033 0.3465
Echinococcus granulosus Transglutaminase 0.0069 0.0658 0.0785
Loa Loa (eye worm) hypothetical protein 0.0303 0.3319 0.4057
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0147 0.1541 0.1864
Echinococcus granulosus flap endonuclease 1 0.0026 0.0164 0.0195
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0021 0.0103 0.0245
Schistosoma mansoni proteasome catalytic subunit 3 (T01 family) 0.0075 0.0718 0.0882
Echinococcus multilocularis protein jagged 2 0.0034 0.0255 0.0255
Trypanosoma cruzi hypothetical protein, conserved 0.0077 0.0746 0.1239
Echinococcus granulosus cysteine protease 0.0051 0.0443 0.0528
Toxoplasma gondii cathepsin CPL 0.0098 0.0984 0.1652
Loa Loa (eye worm) hypothetical protein 0.0034 0.0255 0.0279
Echinococcus granulosus TGF beta signal transducer SmadC 0.0018 0.0077 0.0092
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0098 0.0984 0.3289
Loa Loa (eye worm) hypothetical protein 0.0032 0.0237 0.0257
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0074 0.0091
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0018 0.0074 0.0079
Brugia malayi exodeoxyribonuclease III family protein 0.004 0.032 0.036
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.0107 0.0127
Mycobacterium ulcerans transglutaminase family protein 0.0069 0.0658 0.066
Loa Loa (eye worm) Notch2 0.0034 0.0255 0.0279
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0077 0.0746 0.0885
Schistosoma mansoni notch 0.0034 0.0255 0.0313
Echinococcus multilocularis ETS transcription factor Elf 5 0.0021 0.0111 0.0111
Toxoplasma gondii NADPH-glutathione reductase 0.0019 0.0085 0.0097
Leishmania major trypanothione reductase 0.0055 0.0493 0.0803
Brugia malayi cathepsin L precursor 0.0018 0.0074 0.0058
Plasmodium vivax importin-beta 2, putative 0.0028 0.0192 0.1294
Echinococcus granulosus tumor protein p63 0.0749 0.8388 1
Leishmania major p-glycoprotein 0.0021 0.0103 0.0129
Trypanosoma brucei serine peptidase, Clan SC, Family S9B 0.0055 0.0492 0.0801
Loa Loa (eye worm) hypothetical protein 0.0021 0.0103 0.0092
Schistosoma mansoni laminin gamma-3 chain 0.0034 0.0255 0.0313
Brugia malayi Cathepsin L-like precursor 0.0066 0.0615 0.0725
Trypanosoma cruzi major cysteine proteinase, putative 0.0018 0.0074 0.0079
Schistosoma mansoni cathepsin s 0.0032 0.0237 0.0292
Brugia malayi prolyl oligopeptidase family protein 0.0055 0.0492 0.0573
Trypanosoma cruzi cysteine peptidase, putative 0.019 0.2033 0.3465
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0022 0.0121 0.0159
Echinococcus multilocularis neurogenic locus notch protein 0.0034 0.0255 0.0255
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0021 0.0103 0.0103
Trypanosoma cruzi kinesin, putative 0.0016 0.0045 0.0028
Schistosoma mansoni ran 0.0021 0.0107 0.0131
Loa Loa (eye worm) CXXC zinc finger family protein 0.0031 0.0224 0.0241
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.017 0.1805 0.2191
Onchocerca volvulus 0.0098 0.0984 0.1586
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0098 0.0984 0.3289
Onchocerca volvulus Peroxidasin homolog 0.0303 0.3319 0.5655
Mycobacterium leprae conserved hypothetical protein 0.0077 0.0746 0.0751
Entamoeba histolytica cysteine proteinase, putative 0.0066 0.0615 0.6072
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0055 0.0492 0.0604
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.004 0.032 0.0503
Trypanosoma brucei trypanothione reductase 0.0055 0.0493 0.0803
Loa Loa (eye worm) hypothetical protein 0.0043 0.0361 0.041
Echinococcus granulosus cpg binding protein 0.0033 0.0244 0.0291
Entamoeba histolytica cysteine protease, putative 0.0051 0.0443 0.424
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0074 0.0145
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0018 0.0074 0.0145
Schistosoma mansoni hypothetical protein 0.0054 0.0481 0.0591
Trypanosoma cruzi oligopeptidase b 0.0208 0.2232 0.381
Trypanosoma brucei antigen, putative 0.0022 0.0121 0.0159
Schistosoma mansoni hypothetical protein 0.0373 0.4118 0.5059
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0021 0.0103 0.0245
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0019 0.0085 0.0097
Onchocerca volvulus Peroxidase homolog 0.0303 0.3319 0.5655
Plasmodium falciparum multidrug resistance protein 1 0.0021 0.0103 0.0319
Plasmodium falciparum proteasome subunit beta type-5 0.0075 0.0718 0.7071
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0018 0.0074 0.0091
Plasmodium falciparum glutathione reductase 0.0019 0.0085 0.0116
Loa Loa (eye worm) animal heme peroxidase 0.0303 0.3319 0.4057
Trichomonas vaginalis abcb9, putative 0.0021 0.0103 0.0245
Entamoeba histolytica cysteine proteinase 1, putative 0.0051 0.0443 0.424
Plasmodium vivax unspecified product 0.0032 0.0237 0.1791
Loa Loa (eye worm) prolyl oligopeptidase 0.0055 0.0492 0.0571
Schistosoma mansoni polyomavirus enhancer activator 3 pea3 0.0021 0.0111 0.0136
Trypanosoma cruzi cysteine proteinase, putative 0.0051 0.0443 0.0717
Loa Loa (eye worm) ctsf protein 0.0098 0.0984 0.1178
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0022 0.0121 0.0159
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0018 0.0074 0.0058
Schistosoma mansoni ets-related 0.0446 0.4945 0.6075
Echinococcus granulosus inhibitor of apoptosis protein 0.0161 0.1698 0.2024
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0018 0.0074 0.0079
Schistosoma mansoni hypothetical protein 0.0373 0.4118 0.5059
Trypanosoma brucei Dipeptidyl-peptidase 8-like, putative 0.0055 0.0492 0.0801
Loa Loa (eye worm) Smad1 0.0018 0.0077 0.006
Trypanosoma cruzi hypothetical protein, conserved 0.0055 0.0492 0.0801
Brugia malayi Cytochrome P450 family protein 0.0014 0.0029 0.0002
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0019 0.0085 0.0059
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0095 0.0949 0.0949
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0026 0.0164 0.0234
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0018 0.0074 0.0145
Echinococcus multilocularis cathepsin L cysteine protease 0.0098 0.0984 0.0984
Plasmodium falciparum thioredoxin reductase 0.0019 0.0085 0.0116
Brugia malayi transcription factor E74 isoform 0.0021 0.0111 0.0103
Schistosoma mansoni hypothetical protein 0.0161 0.1698 0.2086
Echinococcus granulosus ETS transcription factor Elf 2 0.0021 0.0111 0.0132
Loa Loa (eye worm) hypothetical protein 0.011 0.1115 0.134
Echinococcus granulosus cathepsin L 0.0018 0.0074 0.0089
Schistosoma mansoni ets-related 0.0021 0.0111 0.0136
Brugia malayi Papain family cysteine protease containing protein 0.0018 0.0074 0.0058
Schistosoma mansoni smdr2 0.0021 0.0103 0.0127
Loa Loa (eye worm) hypothetical protein 0.0018 0.0074 0.0056
Echinococcus granulosus thioredoxin glutathione reductase 0.0055 0.0493 0.0588
Schistosoma mansoni cathepsin S (C01 family) 0.0018 0.0074 0.0091
Echinococcus granulosus calpain 0.0022 0.0121 0.0144
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0098 0.0984 0.3289
Entamoeba histolytica cysteine proteinase, putative 0.0051 0.0443 0.424
Loa Loa (eye worm) hypothetical protein 0.0303 0.3319 0.4057
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0162 0.0961
Trypanosoma cruzi oligopeptidase b 0.0208 0.2232 0.381
Mycobacterium leprae Conserved hypothetical protein 0.0069 0.0658 0.066
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0021 0.0103 0.0245
Echinococcus multilocularis importin subunit beta 1 0.0028 0.0192 0.0192
Mycobacterium tuberculosis Conserved hypothetical protein 0.0069 0.0658 0.066
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.004 0.032 0.0359
Loa Loa (eye worm) cathepsin B 0.0018 0.0074 0.0056
Loa Loa (eye worm) hypothetical protein 0.0032 0.0237 0.0257
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0051 0.0443 0.0717
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0021 0.0103 0.0245
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0236 0.2556 0.3116
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0018 0.0074 0.0145
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0021 0.0103 0.0245
Mycobacterium leprae Probable lipase LipE 0.0077 0.0746 0.0751
Trypanosoma cruzi major cysteine proteinase, putative 0.011 0.1123 0.1892
Schistosoma mansoni hypothetical protein 0.0054 0.0481 0.0591
Entamoeba histolytica P-glycoprotein-5 0.0021 0.0103 0.0621
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0034 0.0255 0.0313
Echinococcus granulosus cathepsin l1 0.0098 0.0984 0.1173
Onchocerca volvulus 0.0077 0.0746 0.117
Loa Loa (eye worm) hypothetical protein 0.0034 0.0255 0.0279
Brugia malayi Peroxidasin 0.0303 0.3319 0.4058
Giardia lamblia Proteasome subunit beta type 5 precursor 0.0075 0.0718 1
Brugia malayi Papain family cysteine protease containing protein 0.0051 0.0443 0.0513
Echinococcus granulosus ETS transcription factor Elf 2 0.0021 0.0111 0.0132
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0019 0.0085 0.0071
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0021 0.0103 0.0123
Toxoplasma gondii prolyl endopeptidase 0.0522 0.5813 1
Loa Loa (eye worm) hypothetical protein 0.0161 0.1698 0.2058
Leishmania major cathepsin L-like protease 0.0098 0.0984 0.1652
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0018 0.0074 0.0056
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0492 0.5473 0.5706
Trypanosoma cruzi cysteine peptidase, putative 0.0098 0.0984 0.1652
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0051 0.0443 0.0717
Leishmania major importin beta-1 subunit, putative 0.0023 0.0131 0.0176
Brugia malayi cytochrome P450 0.0014 0.0029 0.0002
Brugia malayi Latrophilin receptor protein 2 0.0054 0.0481 0.0559
Echinococcus granulosus GA binding protein alpha chain 0.0147 0.1541 0.1837
Mycobacterium tuberculosis Probable hydrolase 0.0077 0.0746 0.0751
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.0022 0.0121 0.0159
Giardia lamblia Hypothetical protein 0.0069 0.0658 0.9076
Trypanosoma cruzi cytochrome P450, putative 0.0023 0.0127 0.017
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0021 0.0103 0.0245
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.0107 0.0355
Loa Loa (eye worm) hypothetical protein 0.0034 0.0255 0.0279
Echinococcus multilocularis tumor protein p63 0.0749 0.8388 0.8388
Brugia malayi Calcium binding EGF domain containing protein 0.0034 0.0255 0.0281
Onchocerca volvulus 0.0303 0.3319 0.5655
Loa Loa (eye worm) hypothetical protein 0.0026 0.0162 0.0164
Loa Loa (eye worm) hypothetical protein 0.0077 0.0746 0.0884
Leishmania major cathepsin L-like protease 0.019 0.2033 0.3465
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0098 0.0984 0.3289
Echinococcus multilocularis prolyl endopeptidase 0.0522 0.5813 0.5813
Entamoeba histolytica cysteine protease, putative 0.0051 0.0443 0.424
Mycobacterium tuberculosis Hypothetical protein 0.0069 0.0658 0.066
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0018 0.0074 0.0145
Trichomonas vaginalis glutathione reductase, putative 0.0019 0.0085 0.0181
Echinococcus granulosus ETS transcription factor Elf 1 0.0021 0.0111 0.0132
Brugia malayi Pre-SET motif family protein 0.0034 0.0261 0.0287
Echinococcus multilocularis ATP binding cassette sub family B 0.002 0.0101 0.0101
Loa Loa (eye worm) hypothetical protein 0.0116 0.1192 0.1434
Schistosoma mansoni slit 0.0034 0.0255 0.0313
Loa Loa (eye worm) hypothetical protein 0.0021 0.0111 0.0101
Onchocerca volvulus Prolyl endopeptidase homolog 0.0522 0.5813 1
Toxoplasma gondii acylaminoacyl-peptidase, putative 0.0055 0.0492 0.0801
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0161 0.1698 0.2059
Loa Loa (eye worm) animal heme peroxidase 0.0303 0.3319 0.4057
Schistosoma mansoni cathepsin B (C01 family) 0.0018 0.0074 0.0091
Onchocerca volvulus Cathepsin L homolog 0.0098 0.0984 0.1586
Schistosoma mansoni hypothetical protein 0.0304 0.3323 0.4083
Brugia malayi cathepsin L-like cysteine proteinase 0.0018 0.0074 0.0058
Loa Loa (eye worm) hypothetical protein 0.0077 0.0746 0.0884
Schistosoma mansoni gamma-secretase subunit aph-1 0.0727 0.814 1
Loa Loa (eye worm) cytochrome P450 family protein 0.0052 0.0457 0.0528
Onchocerca volvulus 0.0034 0.0255 0.0315
Plasmodium falciparum glutathione reductase 0.0055 0.0493 0.4602
Trichomonas vaginalis set domain proteins, putative 0.0269 0.2926 1
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0077 0.0746 0.0751
Mycobacterium leprae PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) 0.0208 0.2232 0.231
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0098 0.0984 0.3289
Loa Loa (eye worm) hypothetical protein 0.0303 0.3319 0.4057
Brugia malayi Cytochrome P450 family protein 0.0052 0.0457 0.053
Loa Loa (eye worm) hypothetical protein 0.0303 0.3319 0.4057
Entamoeba histolytica exodeoxyribonuclease III, putative 0.004 0.032 0.2925
Leishmania major cathepsin L-like protease 0.0098 0.0984 0.1652
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.019 0.2033 0.3465
Schistosoma mansoni notch 0.0034 0.0255 0.0313
Echinococcus granulosus peroxidasin 0.0303 0.3319 0.3957
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0107 0.0098
Trichomonas vaginalis taga, putative 0.0021 0.0103 0.0245
Brugia malayi Angiotensin-converting enzyme family protein 0.06 0.67 0.8224
Leishmania major oligopeptidase b 0.0208 0.2232 0.381
Echinococcus granulosus importin subunit beta 1 0.0028 0.0192 0.0229
Loa Loa (eye worm) MH2 domain-containing protein 0.0269 0.2933 0.358
Echinococcus multilocularis cathepsin L cysteine protease 0.0098 0.0984 0.0984
Loa Loa (eye worm) hypothetical protein 0.0303 0.3319 0.4057
Brugia malayi Cathepsin L-like precursor 0.0098 0.0984 0.1179
Onchocerca volvulus 0.0069 0.0658 0.1018
Schistosoma mansoni cpg binding protein 0.0031 0.0224 0.0275
Plasmodium vivax proteasome subunit beta type-5, putative 0.0075 0.0718 0.7071
Trichomonas vaginalis ABC transporter, putative 0.0021 0.0103 0.0245
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0023 0.0127 0.0103
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0095 0.0949 0.1166
Entamoeba histolytica cysteine protease, putative 0.0051 0.0443 0.424
Schistosoma mansoni Mername-AA248 (C02 family) 0.0022 0.0121 0.0149
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0131 0.034
Echinococcus multilocularis Dipeptidyl peptidase 9 0.0055 0.0492 0.0492
Echinococcus multilocularis inhibitor of apoptosis protein 0.0161 0.1698 0.1698
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0022 0.0121 0.0159
Loa Loa (eye worm) hypothetical protein 0.0034 0.0255 0.0279
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0019 0.0085 0.0097
Schistosoma mansoni hypothetical protein 0.0034 0.0255 0.0313
Echinococcus multilocularis ets variant gene 4 0.0021 0.0111 0.0111
Brugia malayi Animal haem peroxidase family protein 0.0303 0.3319 0.4058
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0021 0.0103 0.0123
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0107 0.0135
Brugia malayi Ets-domain containing protein 0.0147 0.1541 0.1865
Plasmodium vivax flap endonuclease 1, putative 0.0026 0.0164 0.0985
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0075 0.0718 0.1191
Brugia malayi cathepsin F-like cysteine proteinase 0.0018 0.0074 0.0058
Echinococcus granulosus prolyl endopeptidase 0.0522 0.5813 0.693
Entamoeba histolytica cysteine protease, putative 0.0018 0.0074 0.0312
Leishmania major cysteine peptidase A (CPA) 0.0098 0.0984 0.1652
Onchocerca volvulus 0.0098 0.0984 0.1586
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0098 0.0984 0.3289
Loa Loa (eye worm) latrophilin receptor protein 2 0.0054 0.0481 0.0558
Trichomonas vaginalis abcb9, putative 0.0021 0.0103 0.0245
Onchocerca volvulus 0.0269 0.2926 0.497
Loa Loa (eye worm) animal heme peroxidase 0.0303 0.3319 0.4057
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0021 0.0103 0.0245
Echinococcus multilocularis calpain 7 (C02 family) 0.0022 0.0121 0.0121
Schistosoma mansoni cathepsin F (C01 family) 0.0098 0.0984 0.1209
Trypanosoma brucei kinesin, putative 0.0016 0.0045 0.0028
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.0261 0.032
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0034 0.0261 0.0261
Brugia malayi Importin beta-1 subunit 0.0028 0.0192 0.0203
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0026 0.0164 0.0234
Brugia malayi Calcium binding EGF domain containing protein 0.0034 0.0255 0.0281
Loa Loa (eye worm) hypothetical protein 0.0034 0.0255 0.0279
Leishmania major cathepsin L-like protease 0.0098 0.0984 0.1652
Echinococcus multilocularis cathepsin b 0.0018 0.0074 0.0074
Leishmania major oligopeptidase B-like protein,serine peptidase, clan SC, family S9A-like protein 0.0208 0.2232 0.381
Loa Loa (eye worm) hypothetical protein 0.0066 0.0615 0.0723
Loa Loa (eye worm) hypothetical protein 0.0034 0.0255 0.0279
Giardia lamblia Transglutaminase/protease, putative 0.0069 0.0658 0.9076
Onchocerca volvulus 0.0303 0.3319 0.5655
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0018 0.0074 0.0145
Loa Loa (eye worm) hypothetical protein 0.0018 0.0074 0.0056
Trypanosoma cruzi cysteine proteinase, putative 0.0051 0.0443 0.0717
Loa Loa (eye worm) hypothetical protein 0.0018 0.0074 0.0056
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.019 0.2033 0.3465
Echinococcus multilocularis multidrug resistance protein 1 0.0014 0.0032 0.0032
Entamoeba histolytica cysteine proteinase 2 0.0051 0.0443 0.424
Entamoeba histolytica cysteine protease, putative 0.0051 0.0443 0.424
Brugia malayi Cathepsin L-like precursor 0.0098 0.0984 0.1179
Echinococcus multilocularis ETS transcription factor Elf 2 0.0021 0.0111 0.0111
Echinococcus multilocularis beta LACTamase domain containing family member 0.0077 0.0746 0.0746
Echinococcus granulosus slit 2 protein 0.0034 0.0255 0.0304
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0522 0.5813 0.7141
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0034 0.0261 0.032
Entamoeba histolytica cysteine protease, putative 0.0018 0.0074 0.0312
Brugia malayi Animal haem peroxidase family protein 0.0303 0.3319 0.4058
Entamoeba histolytica P-glycoprotein-2, putative 0.0021 0.0103 0.0621
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0125 0.1293 0.1325
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0032 0.0237 0.0257
Echinococcus multilocularis protein jagged 1 0.0034 0.0255 0.0255
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0098 0.0984 0.3289
Brugia malayi GCC2 and GCC3 family protein 0.0034 0.0255 0.0281
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0018 0.0074 0.0145
Loa Loa (eye worm) hypothetical protein 0.0034 0.0255 0.0279
Echinococcus multilocularis ETS domain containing protein Elk 1 0.0021 0.0111 0.0111
Leishmania major proteasome beta 5 subunit, putative 0.0075 0.0718 0.1191
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0158 0.1664 0.2828
Trypanosoma brucei serine peptidase, clan SC, family S9A-like protein 0.0208 0.2232 0.381
Mycobacterium ulcerans hypothetical protein 0.0077 0.0746 0.0751
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0019 0.0085 0.0097
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0019 0.0085 0.0097
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0034 0.0255 0.0315
Loa Loa (eye worm) hypothetical protein 0.0303 0.3319 0.4057
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0019 0.0085 0.0097
Brugia malayi gamma-secretase subunit aph-1 0.0727 0.814 1
Onchocerca volvulus Putative cubilin 0.0034 0.0255 0.0315
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.004 0.032 0.0305
Loa Loa (eye worm) hypothetical protein 0.0034 0.0255 0.0279
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0055 0.0492 0.4758
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0095 0.0949 0.1131
Echinococcus multilocularis cathepsin L 0.0051 0.0443 0.0443
Loa Loa (eye worm) hypothetical protein 0.0034 0.0255 0.0279
Brugia malayi calpain family protein 1 0.0059 0.0538 0.0629
Brugia malayi DNA-binding protein D-ETS-3 0.0021 0.0111 0.0103
Trypanosoma cruzi kinesin, putative 0.0016 0.0045 0.0028
Brugia malayi Cathepsin L-like precursor 0.0066 0.0615 0.0725
Treponema pallidum exodeoxyribonuclease (exoA) 0.004 0.032 1
Echinococcus multilocularis smad 0.0018 0.0077 0.0077
Entamoeba histolytica cysteine protease, putative 0.0098 0.0984 1
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0022 0.0121 0.0159
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0018 0.0074 0.0145
Schistosoma mansoni hypothetical protein 0.0034 0.0255 0.0313
Loa Loa (eye worm) hypothetical protein 0.0303 0.3319 0.4057
Brugia malayi Cytochrome P450 family protein 0.0023 0.0127 0.0123
Loa Loa (eye worm) notch protein 0.0034 0.0255 0.0279
Brugia malayi Papain family cysteine protease containing protein 0.0018 0.0074 0.0058
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0074 0.0145
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0021 0.0103 0.0245
Echinococcus granulosus cathepsin b 0.0018 0.0074 0.0089
Entamoeba histolytica cysteine protease, putative 0.0051 0.0443 0.424
Loa Loa (eye worm) hypothetical protein 0.0303 0.3319 0.4057
Echinococcus granulosus cathepsin L cysteine proteinase 0.0098 0.0984 0.1173
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0055 0.0492 0.4758
Onchocerca volvulus Dual oxidase homolog 0.0303 0.3319 0.5655
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.019 0.2033 0.3465
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0022 0.0121 0.0159
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0098 0.0984 0.3289
Trypanosoma brucei cysteine peptidase C (CPC) 0.0018 0.0074 0.0079
Loa Loa (eye worm) hypothetical protein 0.0037 0.0285 0.0316
Brugia malayi EGF-like domain containing protein 0.0034 0.0255 0.0281
Loa Loa (eye worm) beta-lactamase 0.0077 0.0746 0.0884
Echinococcus granulosus cathepsin L cysteine protease 0.0051 0.0443 0.0528
Schistosoma mansoni cytochrome P450 0.0014 0.0029 0.0035
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0019 0.0085 0.0097
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0098 0.0984 0.3289
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0074 0.0145
Echinococcus granulosus geminin 0.0373 0.4118 0.4909
Trypanosoma brucei proteasome subunit beta type-5, putative 0.0075 0.0718 0.1191
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0018 0.0074 0.0312
Brugia malayi EGF-like domain containing protein 0.0034 0.0255 0.0281
Leishmania major kinesin, putative 0.0016 0.0045 0.0028
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0162 0.023
Brugia malayi beta-lactamase family protein 0.0077 0.0746 0.0885
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0095 0.0949 0.1131
Trypanosoma cruzi cysteine peptidase, putative 0.019 0.2033 0.3465
Loa Loa (eye worm) hypothetical protein 0.0059 0.0538 0.0628
Trypanosoma cruzi Aph-1 protein, putative 0.0283 0.3091 0.5295
Onchocerca volvulus 0.0098 0.0984 0.1586
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0054 0.0481 0.0574
Onchocerca volvulus 0.0034 0.0261 0.0325
Loa Loa (eye worm) hypothetical protein 0.017 0.1805 0.219
Schistosoma mansoni elf1 0.0021 0.0111 0.0136
Trichomonas vaginalis D-aminoacylase, putative 0.0077 0.0746 0.2465
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0018 0.0074 0.0079
Echinococcus multilocularis cysteine protease 0.0098 0.0984 0.0984
Entamoeba histolytica hypothetical protein, conserved 0.0055 0.0492 0.4758
Toxoplasma gondii ATP-binding cassette transporter ABC.B1 0.0021 0.0103 0.0129
Onchocerca volvulus 0.0098 0.0984 0.1586
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0077 0.0746 0.0751
Onchocerca volvulus Chorion peroxidase homolog 0.0303 0.3319 0.5655
Entamoeba histolytica cysteine protease, putative 0.0018 0.0074 0.0312
Trypanosoma brucei cytochrome P450, putative 0.0023 0.0127 0.017
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0074 0.0145
Brugia malayi calpain 5 0.0016 0.0045 0.0022
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0022 0.0121 0.0159
Brugia malayi MH2 domain containing protein 0.0018 0.0077 0.0061
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0022 0.0121 0.0159
Echinococcus multilocularis mothers against decapentaplegic 5 0.0018 0.0077 0.0077
Echinococcus multilocularis neurogenic locus protein delta 0.0034 0.0255 0.0255
Brugia malayi Animal haem peroxidase family protein 0.0303 0.3319 0.4058
Toxoplasma gondii EGF family domain-containing protein 0.0034 0.0255 0.0391
Onchocerca volvulus Peroxidase homolog 0.0303 0.3319 0.5655
Brugia malayi Cathepsin L-like precursor 0.0098 0.0984 0.1179
Echinococcus granulosus mothers against decapentaplegic 5 0.0018 0.0077 0.0092
Trypanosoma cruzi oligopeptidase B-like protein, putative 0.0208 0.2232 0.381
Leishmania major ATP-binding cassette protein subfamily B, member 2, putative 0.0021 0.0103 0.0129
Schistosoma mansoni acylaminoacyl-peptidase (S09 family) 0.0055 0.0492 0.0604
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0074 0.0091
Entamoeba histolytica cysteine proteinase, putative 0.0051 0.0443 0.424
Loa Loa (eye worm) hypothetical protein 0.0126 0.1298 0.1565
Brugia malayi Smad1 0.0018 0.0077 0.0061
Echinococcus granulosus cathepsin l cysteine peptidase 0.0098 0.0984 0.1173
Echinococcus multilocularis neurogenic locus notch protein 0.0034 0.0255 0.0255
Loa Loa (eye worm) transcription factor SMAD2 0.0269 0.2933 0.358
Loa Loa (eye worm) hypothetical protein 0.0054 0.0481 0.0558
Onchocerca volvulus Peroxidasin homolog 0.0303 0.3319 0.5655
Brugia malayi EGF-like domain containing protein 0.0034 0.0255 0.0281
Brugia malayi EGF-like domain containing protein 0.0034 0.0255 0.0281
Loa Loa (eye worm) thioredoxin reductase 0.0055 0.0493 0.0572
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0018 0.0074 0.0145
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0075 0.0718 0.2368
Loa Loa (eye worm) hypothetical protein 0.0018 0.0074 0.0056
Onchocerca volvulus 0.0098 0.0984 0.1586
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0019 0.0085 0.0116
Schistosoma mansoni ran 0.0021 0.0107 0.0131
Entamoeba histolytica cysteine proteinase, putative 0.0051 0.0443 0.424
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0021 0.0107 0.0502
Trichomonas vaginalis mercuric reductase, putative 0.0019 0.0085 0.0181
Schistosoma mansoni calpain-7 (C02 family) 0.0026 0.0159 0.0195
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0098 0.0984 0.3289
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0019 0.0085 0.0101
Trichomonas vaginalis ABC transporter, putative 0.0021 0.0103 0.0245
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.0261 0.032
Brugia malayi MH2 domain containing protein 0.0269 0.2933 0.3581
Loa Loa (eye worm) hypothetical protein 0.0034 0.0255 0.0279
Brugia malayi Blistered cuticle protein 3 0.0303 0.3319 0.4058
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0019 0.0085 0.0097
Brugia malayi cathepsin F-like cysteine proteinase 0.0032 0.0237 0.0259
Echinococcus multilocularis cpg binding protein 0.0033 0.0244 0.0244
Trypanosoma brucei Alpha/beta hydrolase domain-containing protein 0.0055 0.0492 0.0801
Brugia malayi ABC transporter family protein 0.0021 0.0103 0.0094
Plasmodium vivax multidrug resistance protein 1, putative 0.0021 0.0103 0.0319
Entamoeba histolytica cysteine protease, putative 0.0051 0.0443 0.424
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.004 0.032 0.3815
Toxoplasma gondii preprocathepsin c precursor, putative 0.0018 0.0074 0.0079
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.0107 0.0107
Loa Loa (eye worm) hypothetical protein 0.0161 0.1698 0.2058
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0139 0.1452 0.1492
Trichomonas vaginalis penicillin-binding protein, putative 0.0077 0.0746 0.2465
Echinococcus multilocularis neurogenic locus protein delta 0.0034 0.0255 0.0255
Onchocerca volvulus Dipeptidyl peptidase family member 1 homolog 0.0055 0.0492 0.0728
Mycobacterium ulcerans esterase/lipase LipP 0.0077 0.0746 0.0751
Echinococcus granulosus multidrug resistance protein 1 0.0021 0.0103 0.0123
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.004 0.032 0.0381
Plasmodium vivax thioredoxin reductase, putative 0.0055 0.0493 0.4602
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0098 0.0984 0.3289

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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