Detailed information for compound 116316

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 396.93 | Formula: C16H29ClN2O5S
  • H donors: 5 H acceptors: 4 LogP: 0.67 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: CSC1OC(C(C(Cl)C)NC(=O)[C@@H]2CCCCCN2)C(C(C1O)O)O
  • InChi: 1S/C16H29ClN2O5S/c1-8(17)10(19-15(23)9-6-4-3-5-7-18-9)14-12(21)11(20)13(22)16(24-14)25-2/h8-14,16,18,20-22H,3-7H2,1-2H3,(H,19,23)/t8?,9-,10?,11?,12?,13?,14?,16?/m0/s1
  • InChiKey: ASHMFMVNXDZCCZ-ZILJDAMMSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis cyclins, putative 0.0042 0.0014 0.0092
Loa Loa (eye worm) hypothetical protein 0.0195 0.0124 0.0308
Plasmodium vivax M1-family alanyl aminopeptidase, putative 0.0049 0.0019 0.0112
Entamoeba histolytica hypothetical protein 0.0201 0.0128 0.5533
Schistosoma mansoni neuropeptide receptor 0.0195 0.0124 0.0124
Schistosoma mansoni nuclear hormone receptor 0.0078 0.004 0.004
Schistosoma mansoni ankyrin 23/unc44 0.0029 0.0004 0.0004
Onchocerca volvulus 0.0071 0.0035 0.075
Schistosoma mansoni DNA repair protein RAD51 0.0024 0.0001 0.0001
Echinococcus multilocularis protein patched 0.0529 0.0363 0.0599
Schistosoma mansoni patched 1 0.0529 0.0363 0.0363
Trichomonas vaginalis conserved hypothetical protein 0.0079 0.0041 0.0272
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0638 0.0441 0.0441
Schistosoma mansoni hypothetical protein 0.0056 0.0024 0.0024
Echinococcus multilocularis Niemann Pick C1 protein 0.0529 0.0363 0.0599
Schistosoma mansoni protein kinase 0.0029 0.0005 0.0005
Schistosoma mansoni membrane associated guanylate kinase inverted related 0.0032 0.0007 0.0007
Schistosoma mansoni retinoic acid receptor RXR 0.0166 0.0103 0.0103
Onchocerca volvulus Netrin receptor homolog 0.0029 0.0004 0.006
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0113 0.0065 0.0162
Loa Loa (eye worm) hypothetical protein 0.0078 0.004 0.01
Loa Loa (eye worm) hypothetical protein 0.0195 0.0124 0.0308
Mycobacterium ulcerans aminopeptidase N PepN 0.0049 0.0019 0.0045
Loa Loa (eye worm) melatonin receptor type 1A 0.0195 0.0124 0.0308
Echinococcus multilocularis dro:myosuppressin receptor 0.0195 0.0124 0.0203
Trypanosoma cruzi ribonucleoside-diphosphate reductase large chain, putative 0.0643 0.0445 0.2608
Trichomonas vaginalis proprotein convertase subtilisin/kexin type, putative 0.0048 0.0019 0.0125
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0045 0.0016 0.0107
Brugia malayi hypothetical protein 0.0195 0.0124 0.0308
Schistosoma mansoni biogenic amine (5HT) receptor 0.0195 0.0124 0.0124
Trypanosoma cruzi metacaspase, putative 0.0079 0.0041 0.0237
Schistosoma mansoni hypothetical protein 0.0971 0.068 0.068
Brugia malayi Stress-activated protein kinase jnk-1 0.0231 0.015 0.0373
Leishmania major 3-hydroxy-3-methylglutaryl-CoA reductase 0.1286 0.0906 0.5307
Echinococcus granulosus aminopeptidase N 0.0474 0.0323 0.0533
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.849 0.6071 1
Brugia malayi Integrin beta pat-3 precursor 0.561 0.4006 1
Echinococcus granulosus alpha 1A adrenergic receptor 0.0195 0.0124 0.0203
Echinococcus multilocularis g protein coupled receptor 0.0195 0.0124 0.0203
Brugia malayi Copper type II ascorbate-dependent monooxygenase, C-terminal domain containing protein 0.0244 0.0159 0.0397
Schistosoma mansoni high voltage-activated calcium channel beta subunit 2 0.0027 0.0003 0.0003
Schistosoma mansoni hypothetical protein 0.0109 0.0062 0.0062
Loa Loa (eye worm) hypothetical protein 0.0534 0.0367 0.0916
Onchocerca volvulus Bile acid receptor homolog 0.0166 0.0103 0.2298
Schistosoma mansoni serine/threonine protein kinase 0.0154 0.0095 0.0095
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0079 0.0041 0.0272
Giardia lamblia High cysteine protein 0.0133 0.008 0.1913
Trypanosoma brucei ribonucleoside-diphosphate reductase small chain 0.0135 0.0081 0.0473
Loa Loa (eye worm) hypothetical protein 0.0195 0.0124 0.0308
Echinococcus multilocularis MAGUK p55 subfamily 0.0032 0.0007 0.0012
Onchocerca volvulus Cell death protein 3 homolog 0.0342 0.0229 0.5168
Schistosoma mansoni ribonucleoside-diphosphate reductase small chain 0.0135 0.0081 0.0081
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0014 0.0092
Brugia malayi DNA repair protein RAD51 homolog 1 0.0024 0.0001 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.0079 0.0041 0.0272
Loa Loa (eye worm) hypothetical protein 0.0597 0.0412 0.1027
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0154 0.0095 0.0236
Echinococcus multilocularis leukotriene A 4 hydrolase 0.0049 0.0019 0.0031
Echinococcus multilocularis neuropeptide FF receptor 2 0.0195 0.0124 0.0203
Leishmania major protein kinase, putative 0.0026 0.0002 0.0015
Trypanosoma cruzi DNA repair protein RAD51, putative 0.0024 0.0001 0.0007
Brugia malayi sulfakinin receptor protein 0.0195 0.0124 0.0308
Giardia lamblia Histone acetyltransferase GCN5 0.0041 0.0013 0.0317
Brugia malayi follicle stimulating hormone receptor 0.0195 0.0124 0.0308
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.009 0.0049 0.008
Loa Loa (eye worm) hypothetical protein 0.0088 0.0047 0.0117
Schistosoma mansoni maguk P55 subfamily member 26 0.0027 0.0003 0.0003
Schistosoma mansoni serine/threonine protein kinase 0.0123 0.0072 0.0072
Schistosoma mansoni hypothetical protein 0.0195 0.0124 0.0124
Loa Loa (eye worm) hypothetical protein 0.0195 0.0124 0.0308
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0638 0.0441 0.0441
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0139 0.0084 0.0138
Brugia malayi G protein-coupled receptor 0.0195 0.0124 0.0308
Echinococcus multilocularis MAGUK p55 subfamily 0.0032 0.0007 0.0012
Loa Loa (eye worm) hypothetical protein 0.0027 0.0003 0.0008
Loa Loa (eye worm) hypothetical protein 0.0088 0.0047 0.0117
Entamoeba histolytica cyclin, putative 0.0042 0.0014 0.0593
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0195 0.0124 0.0203
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0195 0.0124 0.0203
Loa Loa (eye worm) hypothetical protein 0.058 0.04 0.0998
Trichomonas vaginalis 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative 0.0603 0.0416 0.28
Loa Loa (eye worm) hypothetical protein 0.0195 0.0124 0.0308
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0078 0.004 0.01
Brugia malayi EGF-like domain containing protein 0.0133 0.008 0.0199
Echinococcus multilocularis kelch ECH associated protein 1 0.073 0.0507 0.0835
Schistosoma mansoni hypothetical protein 0.0029 0.0004 0.0004
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0201 0.0128 0.0211
Echinococcus granulosus kelch ECH associated protein 1 0.073 0.0507 0.0835
Schistosoma mansoni hypothetical protein 0.0056 0.0024 0.0024
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0041 0.0014 0.0034
Brugia malayi Furin-like cysteine rich region family protein 0.006 0.0027 0.0067
Loa Loa (eye worm) G-protein coupled receptor 0.0195 0.0124 0.0308
Schistosoma mansoni hypothetical protein 0.0732 0.0509 0.0509
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.0703 0.0488 0.0803
Loa Loa (eye worm) hypothetical protein 0.0334 0.0224 0.0558
Loa Loa (eye worm) hypothetical protein 0.0107 0.0061 0.0151
Loa Loa (eye worm) hypothetical protein 0.0041 0.0014 0.0034
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0152 0.0093 0.0625
Brugia malayi hypothetical protein 0.0195 0.0124 0.0308
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0107 0.0061 0.0151
Loa Loa (eye worm) hypothetical protein 0.0195 0.0124 0.0308
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0166 0.0103 0.0103
Brugia malayi Nuclear hormone receptor-like 1 0.0088 0.0047 0.0117
Echinococcus granulosus Nuclear hormone receptor HR96 0.0078 0.004 0.0066
Onchocerca volvulus 0.0195 0.0124 0.2771
Brugia malayi nuclear hormone receptor 0.0166 0.0103 0.0256
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0019 0.0125
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0166 0.0103 0.2298
Loa Loa (eye worm) hypothetical protein 0.0027 0.0003 0.0008
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0166 0.0103 0.0256
Loa Loa (eye worm) hypothetical protein 0.0195 0.0124 0.0308
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0166 0.0103 0.0169
Loa Loa (eye worm) aspartyl protease 6 0.0638 0.0441 0.1101
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0195 0.0124 0.0124
Schistosoma mansoni proteasome subunit beta 1 (T01 family) 0.0054 0.0023 0.0023
Schistosoma mansoni MAGUK homolog 0.0032 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0195 0.0124 0.0308
Loa Loa (eye worm) hypothetical protein 0.1573 0.1112 0.2775
Schistosoma mansoni integrin alpha 0.2485 0.1766 0.1766
Plasmodium falciparum plasmepsin II 0.1154 0.0811 0.4753
Loa Loa (eye worm) hypothetical protein 0.0195 0.0124 0.0308
Brugia malayi Cell death protein 3 precursor 0.0342 0.0229 0.0571
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.0056 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.0133 0.008 0.0199
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0166 0.0103 0.0256
Plasmodium falciparum plasmepsin V 0.0638 0.0441 0.2584
Plasmodium vivax metacaspase 1, putative 0.0079 0.0041 0.0237
Schistosoma mansoni hypothetical protein 0.0124 0.0073 0.0073
Trypanosoma cruzi metallo-peptidase, Clan MA(E) Family M1 0.0049 0.0019 0.0112
Echinococcus multilocularis guanylate kinase 0.0027 0.0003 0.0005
Trichomonas vaginalis teneurin and N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase, putative 0.0133 0.008 0.0535
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0166 0.0103 0.0256
Loa Loa (eye worm) hypothetical protein 0.0078 0.004 0.01
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0195 0.0124 0.0203
Echinococcus multilocularis integrin alpha 3 0.1905 0.135 0.2223
Echinococcus granulosus death domain containing protein 0.0029 0.0004 0.0007
Entamoeba histolytica proteasome subunit beta type 1, putative 0.0054 0.0023 0.0991
Echinococcus multilocularis allatostatin A receptor 0.0333 0.0223 0.0367
Schistosoma mansoni mannosidase endo-alpha 0.0027 0.0003 0.0003
Brugia malayi Immunoglobulin I-set domain containing protein 0.0029 0.0004 0.0011
Leishmania major proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative 0.0054 0.0023 0.0134
Loa Loa (eye worm) nuclear receptor NHR-67 0.0078 0.004 0.01
Schistosoma mansoni ribonucleoside-diphosphate reductase alpha subunit 0.2403 0.1707 0.1707
Echinococcus multilocularis 0.0202 0.0129 0.0212
Schistosoma mansoni neuropeptide receptor 0.0195 0.0124 0.0124
Echinococcus multilocularis nuclear receptor nhr 48 0.0078 0.004 0.0066
Trichomonas vaginalis cyclin B, putative 0.0042 0.0014 0.0092
Brugia malayi Guanylate kinase family protein 0.0108 0.0061 0.0153
Giardia lamblia Tenascin-37 0.0133 0.008 0.1913
Echinococcus granulosus ecdysone induced protein 78C 0.0166 0.0103 0.0169
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0019 0.0125
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0027 0.0004 0.0024
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0029 0.0004 0.0011
Plasmodium falciparum M1-family alanyl aminopeptidase 0.0049 0.0019 0.0112
Echinococcus granulosus aryl hydrocarbon receptor 0.0025 0.0002 0.0003
Schistosoma mansoni netrin receptor unc5 0.0029 0.0004 0.0004
Schistosoma mansoni nuclear hormone receptor 0.0166 0.0103 0.0103
Loa Loa (eye worm) RGC/RGC protein kinase 0.0029 0.0005 0.0013
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0166 0.0103 0.0256
Brugia malayi neuroendocrine convertase 1 precursor 0.0157 0.0097 0.0241
Loa Loa (eye worm) proprotein convertase 2 0.0059 0.0026 0.0066
Echinococcus multilocularis neuropeptide receptor 0.0195 0.0124 0.0203
Brugia malayi RE15519p 0.0195 0.0124 0.0308
Brugia malayi hypothetical protein 0.0195 0.0124 0.0308
Onchocerca volvulus 0.0124 0.0073 0.1614
Echinococcus granulosus 7tm_1 domain containing protein 0.0195 0.0124 0.0203
Toxoplasma gondii guanylate kinase family protein 0.0027 0.0003 0.0018
Echinococcus granulosus fibrillin 2 0.0133 0.008 0.0131
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0195 0.0124 0.2771
Schistosoma mansoni neuropeptide receptor 0.0195 0.0124 0.0124
Echinococcus multilocularis nmda type glutamate receptor 0.0026 0.0003 0.0004
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0166 0.0103 0.0256
Trypanosoma cruzi metacaspase, putative 0.0079 0.0041 0.0237
Schistosoma mansoni cell polarity protein 0.0037 0.001 0.001
Loa Loa (eye worm) pigment dispersing factor receptor c 0.142 0.1002 0.2501
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0014 0.0092
Echinococcus granulosus g protein coupled receptor 0.0195 0.0124 0.0203
Echinococcus granulosus MAGUK p55 subfamily 0.0032 0.0007 0.0012
Loa Loa (eye worm) hypothetical protein 0.1371 0.0967 0.2413
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0166 0.0103 0.0256
Schistosoma mansoni hypothetical protein 0.0124 0.0073 0.0073
Loa Loa (eye worm) hypothetical protein 0.0195 0.0124 0.0308
Echinococcus granulosus membrane associated guanylate kinase ww and pdz 0.0032 0.0007 0.0012
Brugia malayi hypothetical protein 0.0078 0.004 0.01
Brugia malayi hypothetical protein 0.0195 0.0124 0.0308
Echinococcus granulosus tissue type plasminogen activator 0.0092 0.005 0.0082
Brugia malayi Eukaryotic aspartyl protease family protein 0.0638 0.0441 0.1101
Schistosoma mansoni apoptosis regulator bax 0.0056 0.0024 0.0024
Echinococcus multilocularis integrin alpha ps 0.0534 0.0367 0.0604
Brugia malayi hypothetical protein 0.0638 0.0441 0.1101
Trypanosoma cruzi hypothetical protein, conserved 0.0092 0.005 0.0291
Brugia malayi Dopamine receptor protein 2 0.0195 0.0124 0.0308
Echinococcus granulosus rhodopsin orphan GPCR 0.0195 0.0124 0.0203
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.1154 0.0811 0.1336
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0019 0.0125
Echinococcus multilocularis Kelch repeat type 1 0.0732 0.0509 0.0838
Echinococcus granulosus tachykinin peptides receptor 99D 0.077 0.0536 0.0882
Trichomonas vaginalis bromodomain-containing protein, putative 0.0045 0.0016 0.0107
Trichomonas vaginalis cyclin B, putative 0.0042 0.0014 0.0092
Onchocerca volvulus 0.0195 0.0124 0.2771
Echinococcus multilocularis integrin alpha ps 0.1114 0.0783 0.1289
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0049 0.0019 0.0031
Schistosoma mansoni hypothetical protein 0.0195 0.0124 0.0124
Brugia malayi Peptidase family M1 containing protein 0.0474 0.0323 0.0807
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0166 0.0103 0.0169
Trypanosoma brucei ribonucleoside-diphosphate reductase small chain 0.0046 0.0017 0.0098
Echinococcus granulosus neuropeptide receptor A26 0.0195 0.0124 0.0203
Schistosoma mansoni alpha-1 adrenergic receptor 0.0195 0.0124 0.0124
Echinococcus granulosus sex peptide receptor 0.0195 0.0124 0.0203
Echinococcus multilocularis proprotein convertase subtilisin:kexin type 5 0.0152 0.0093 0.0153
Chlamydia trachomatis ribonucleoside-diphosphate reductase subunit beta 0.0135 0.0081 0.0463
Onchocerca volvulus 0.0195 0.0124 0.2771
Loa Loa (eye worm) hypothetical protein 0.0195 0.0124 0.0308
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0195 0.0124 0.0124
Trypanosoma brucei metacaspase MCA3 0.0079 0.0041 0.0237
Loa Loa (eye worm) hypothetical protein 0.0078 0.004 0.01
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0195 0.0124 0.0124
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0019 0.0125
Mycobacterium leprae conserved hypothetical protein 0.0306 0.0203 0.1358
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0054 0.0023 0.0038
Loa Loa (eye worm) hypothetical protein 0.0195 0.0124 0.0308
Echinococcus multilocularis high voltage activated calcium channel beta 0.0027 0.0003 0.0005
Loa Loa (eye worm) hypothetical protein 0.0107 0.0061 0.0151
Trypanosoma cruzi cyclin, putative 0.0042 0.0014 0.008
Brugia malayi hypothetical protein 0.0088 0.0047 0.0117
Loa Loa (eye worm) endoprotease bli-4 0.025 0.0163 0.0407
Echinococcus multilocularis caspase 8 0.0079 0.0041 0.0067
Loa Loa (eye worm) neuropeptide F receptor 0.0195 0.0124 0.0308
Schistosoma mansoni hypothetical protein 0.0534 0.0367 0.0367
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0041 0.0014 0.0014
Trypanosoma brucei ribonucleoside-diphosphate reductase small chain 0.0135 0.0081 0.0473
Mycobacterium tuberculosis Conserved hypothetical protein 0.0345 0.0231 0.064
Loa Loa (eye worm) hypothetical protein 0.0049 0.0019 0.0048
Toxoplasma gondii eukaryotic aspartyl protease superfamily protein 0.0638 0.0441 0.2584
Loa Loa (eye worm) hypothetical protein 0.0195 0.0124 0.0308
Echinococcus multilocularis kelch ECH associated protein 1 0.073 0.0507 0.0835
Onchocerca volvulus 0.0049 0.0019 0.0394
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0124 0.0073 0.012
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0195 0.0124 0.0124
Echinococcus granulosus caspase 8 0.0079 0.0041 0.0067
Brugia malayi aspartic protease BmAsp-1, identical 0.0638 0.0441 0.1101
Plasmodium vivax guanylate kinase, putative 0.0027 0.0003 0.0018
Trichomonas vaginalis replication factor A 1, rfa1, putative 0.0039 0.0012 0.008
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0195 0.0124 0.0203
Echinococcus multilocularis receptor type guanylyl cyclase 0.0029 0.0005 0.0008
Onchocerca volvulus 0.0166 0.0103 0.2298
Onchocerca volvulus 0.0638 0.0441 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0195 0.0124 0.0124
Trichomonas vaginalis guanylate kinase, putative 0.0027 0.0003 0.0021
Schistosoma mansoni subfamily S8B non-peptidase homologue (S08 family) 0.0059 0.0026 0.0026
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0166 0.0103 0.0169
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.0056 0.0024 0.004
Trypanosoma cruzi ribonucleoside-diphosphate reductase large chain, putative 0.2403 0.1707 1
Echinococcus multilocularis axis inhibition protein axin 0.0041 0.0014 0.0022
Echinococcus granulosus dro:myosuppressin receptor 0.0195 0.0124 0.0203
Echinococcus multilocularis fibrillin 1 0.0133 0.008 0.0131
Schistosoma mansoni leukotriene A4 hydrolase (M01 family) 0.0049 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.0195 0.0124 0.0308
Entamoeba histolytica acetyltransferase, GNAT family 0.0041 0.0013 0.0571
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0029 0.0004 0.0007
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0231 0.015 0.0373
Trichomonas vaginalis cyclins, putative 0.0042 0.0014 0.0092
Echinococcus granulosus tm gpcr rhodopsin 0.0195 0.0124 0.0203
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.0139 0.0084 0.0564
Trichomonas vaginalis ribonucleoside-diphosphate reductase alpha chain, putative 0.2097 0.1487 1
Mycobacterium ulcerans hypothetical protein 0.0345 0.0231 0.064
Trypanosoma cruzi aminopeptidase, putative 0.0139 0.0084 0.0491
Echinococcus multilocularis protein dispatched 1 0.0529 0.0363 0.0599
Schistosoma mansoni hypothetical protein 0.0107 0.0061 0.0061
Echinococcus multilocularis regulator of G protein signaling 0.0041 0.0014 0.0022
Loa Loa (eye worm) hypothetical protein 0.0042 0.0014 0.0034
Schistosoma mansoni peptidylglycine monooxygenase 0.0244 0.0159 0.0159
Schistosoma mansoni serine/threonine protein kinase 0.0231 0.015 0.015
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0195 0.0124 0.0124
Giardia lamblia Neurogenic locus Notch protein precursor 0.0133 0.008 0.1913
Brugia malayi ecdysteroid receptor 0.0166 0.0103 0.0256
Loa Loa (eye worm) hypothetical protein 0.0078 0.004 0.01
Schistosoma mansoni axis inhibition protein axin 0.0041 0.0014 0.0014
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0195 0.0124 0.0308
Brugia malayi bHLH-PAS transcription factor 0.0071 0.0035 0.0087
Echinococcus multilocularis thyroid hormone receptor alpha 0.029 0.0192 0.0316
Echinococcus granulosus thymidine phosphorylase 0.5002 0.357 0.5881
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0029 0.0004 0.0004
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0638 0.0441 0.0441
Echinococcus multilocularis high voltage activated calcium channel beta 0.0027 0.0003 0.0005
Leishmania major ribonucleoside-diphosphate reductase small chain, putative 0.0135 0.0081 0.0473
Brugia malayi Regulator of G protein signaling domain containing protein 0.0041 0.0014 0.0034
Loa Loa (eye worm) leukotriene A4 hydrolase 0.0049 0.0019 0.0048
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0166 0.0103 0.0256
Schistosoma mansoni amine GPCR 0.0195 0.0124 0.0124
Schistosoma mansoni subfamily S8B unassigned peptidase (S08 family) 0.025 0.0163 0.0163
Plasmodium falciparum histone acetyltransferase GCN5 0.0041 0.0013 0.0077
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0059 0.0026 0.0177
Loa Loa (eye worm) hypothetical protein 0.0638 0.0441 0.1101
Giardia lamblia Tenascin-X 0.0133 0.008 0.1913
Echinococcus granulosus tm gpcr rhodopsin 0.0195 0.0124 0.0203
Trichomonas vaginalis cyclin B, putative 0.0042 0.0014 0.0092
Giardia lamblia Furin precursor putative serine protease 0.0048 0.0019 0.0447
Brugia malayi putative neuropeptide receptor NPR1 0.0195 0.0124 0.0308
Loa Loa (eye worm) hypothetical protein 0.0166 0.0103 0.0256
Onchocerca volvulus 0.0043 0.0015 0.03
Schistosoma mansoni nuclear receptor 0.0078 0.004 0.004
Loa Loa (eye worm) PXA domain-containing protein 0.0041 0.0014 0.0034
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0195 0.0124 0.0203
Loa Loa (eye worm) hypothetical protein 0.0195 0.0124 0.0308
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0025 0.0002 0.001
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0029 0.0005 0.0075
Entamoeba histolytica aminopeptidase, putative 0.0139 0.0084 0.3626
Brugia malayi hypothetical protein 0.0195 0.0124 0.0308
Loa Loa (eye worm) hypoxia-induced factor 1 0.0296 0.0196 0.049
Mycobacterium ulcerans anthranilate phosphoribosyltransferase 0.1412 0.0996 0.2784
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0059 0.0026 0.0177
Loa Loa (eye worm) hypothetical protein 0.0195 0.0124 0.0308
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0449 0.0306 0.0504
Schistosoma mansoni memapsin-2 (A01 family) 0.9892 0.7076 0.7076
Schistosoma mansoni caspase-7 (C14 family) 0.0149 0.0091 0.0091
Echinococcus multilocularis g-protein coupled receptor 0.0195 0.0124 0.0203
Schistosoma mansoni coup transcription factor 0.0166 0.0103 0.0103
Mycobacterium tuberculosis Ribonucleoside-diphosphate reductase (beta chain) NrdB (ribonucleotide reductase small chain) 0.0135 0.0081 0.0218
Echinococcus granulosus G protein coupled receptor 139 0.0195 0.0124 0.0203
Schistosoma mansoni regulator of G protein signaling 0.0041 0.0014 0.0014
Brugia malayi Peptidase family M1 containing protein 0.0049 0.0019 0.0048
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0026 0.0002 0.0015
Brugia malayi G protein-coupled receptor F59B2.13 0.0195 0.0124 0.0308
Echinococcus multilocularis rhodopsin orphan GPCR 0.0195 0.0124 0.0203
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0195 0.0124 0.0203
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0151 0.0092 0.0092
Trypanosoma cruzi DNA repair protein RAD51, putative 0.0024 0.0001 0.0007
Entamoeba histolytica hypothetical protein 0.0041 0.0014 0.0589
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0195 0.0124 0.0203
Brugia malayi nuclear receptor RXR 0.0078 0.004 0.01
Schistosoma mansoni MAGUK homolog 0.0033 0.0008 0.0008
Loa Loa (eye worm) latrophilin receptor protein 2 0.0449 0.0306 0.0764
Onchocerca volvulus 0.0195 0.0124 0.2771
Mycobacterium ulcerans hypothetical protein 0.0345 0.0231 0.064
Brugia malayi PXA domain containing protein 0.0041 0.0014 0.0034
Schistosoma mansoni peptidyl-glycine monooxygenase 0.046 0.0313 0.0313
Schistosoma mansoni biogenic amine receptor 0.0195 0.0124 0.0124
Mycobacterium ulcerans ribonucleotide-diphosphate reductase subunit alpha 0.2097 0.1487 0.4161
Echinococcus multilocularis rhodopsin orphan GPCR 0.0195 0.0124 0.0203
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0079 0.0041 0.0101
Loa Loa (eye worm) hypothetical protein 0.0449 0.0306 0.0764
Loa Loa (eye worm) apoptosis regulator protein 0.0056 0.0024 0.006
Loa Loa (eye worm) hypothetical protein 0.025 0.0163 0.0407
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0078 0.004 0.0066
Schistosoma mansoni hypothetical protein 0.0449 0.0306 0.0306
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0195 0.0124 0.0203
Schistosoma mansoni replication factor A 1 rfa1 0.0039 0.0012 0.0012
Brugia malayi hypoxia-induced factor 1 0.0296 0.0196 0.049
Onchocerca volvulus 0.0195 0.0124 0.2771
Schistosoma mansoni z-protein (S1r protein) 0.0041 0.0014 0.0014
Brugia malayi hypothetical protein 0.0049 0.0019 0.0048
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0078 0.004 0.0066
Brugia malayi Nuclear hormone receptor E75 0.0078 0.004 0.01
Leishmania major metacaspase, putative 0.0079 0.0041 0.0237
Trichomonas vaginalis cyclin B, putative 0.0042 0.0014 0.0092
Loa Loa (eye worm) hypothetical protein 0.0025 0.0002 0.0004
Mycobacterium leprae RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE (BETA CHAIN) NRDF (RIBONUCLEOTIDE REDUCTASE SMALL SUBUNIT) (R2F PROTEIN) 0.0046 0.0017 0.0101
Brugia malayi nuclear receptor NHR-88 0.0078 0.004 0.01
Trypanosoma brucei aminopeptidase, putative 0.0049 0.0019 0.0112
Brugia malayi Copper type II ascorbate-dependent monooxygenase, N-terminal domain containing protein 0.0124 0.0073 0.0182
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0079 0.0041 0.0272
Echinococcus granulosus hydroxymethylglutaryl coenzyme A reductase 0.1286 0.0906 0.1492
Brugia malayi Nuclear hormone receptor-like 1 0.0166 0.0103 0.0256
Echinococcus multilocularis ribonucleoside diphosphate reductase large 0.2403 0.1707 0.2812
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0166 0.0103 0.0256
Trypanosoma cruzi metallo-peptidase, Clan MA(E) Family M1 0.009 0.0049 0.0286
Brugia malayi GnHR receptor homolog 0.0639 0.0442 0.1104
Brugia malayi nuclear receptor RXR 0.0088 0.0047 0.0117
Loa Loa (eye worm) hypothetical protein 0.0195 0.0124 0.0308
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0195 0.0124 0.0308
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0059 0.0026 0.0177
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0166 0.0103 0.0256
Onchocerca volvulus 0.0042 0.0014 0.0272
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0049 0.0019 0.0031
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0025 0.0002 0.0003
Loa Loa (eye worm) neuropeptide F receptor 0.0195 0.0124 0.0308
Schistosoma mansoni adenoreceptor 0.0195 0.0124 0.0124
Trypanosoma cruzi meiotic recombination protein DMC1, putative 0.0024 0.0001 0.0007
Echinococcus multilocularis atrial natriuretic peptide receptor 0.0026 0.0003 0.0004
Loa Loa (eye worm) hypothetical protein 0.0079 0.0041 0.0101
Schistosoma mansoni integrin alpha-ps 0.058 0.04 0.04
Echinococcus multilocularis disks large 3 0.0098 0.0054 0.0089
Plasmodium vivax ribonucleoside-diphosphate reductase small chain, putative 0.0135 0.0081 0.0473
Schistosoma mansoni myosin xvIII 0.0195 0.0124 0.0124
Plasmodium falciparum ribonucleoside-diphosphate reductase small chain, putative 0.0135 0.0081 0.0473
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0195 0.0124 0.0124
Trichomonas vaginalis conserved hypothetical protein 0.0079 0.0041 0.0272
Mycobacterium tuberculosis Ribonucleoside-diphosphate reductase (alpha chain) NrdE (ribonucleotide reductase small subunit) (R1F protein) 0.2097 0.1487 0.4161
Schistosoma mansoni family A2 unassigned peptidase (A02 family) 0.254 0.1805 0.1805
Schistosoma mansoni regulator of G protein signaling 0.0041 0.0014 0.0014
Schistosoma mansoni transcription factor LCR-F1 0.0201 0.0128 0.0128
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0041 0.0014 0.0092
Mycobacterium leprae Probable anthranilate phosphoribosyltransferase TrpD 0.1412 0.0996 0.6694
Schistosoma mansoni biogenic amine receptor 0.0195 0.0124 0.0124
Echinococcus granulosus rhodopsin orphan GPCR 0.0195 0.0124 0.0203
Schistosoma mansoni hypothetical protein 0.0056 0.0024 0.0024
Brugia malayi neuropeptide F receptor 0.0195 0.0124 0.0308
Loa Loa (eye worm) hypothetical protein 0.009 0.0049 0.0122
Loa Loa (eye worm) aspartic protease BmAsp-1 0.0638 0.0441 0.1101
Echinococcus granulosus apoptotic protease activating factor 1 0.0124 0.0073 0.012
Echinococcus granulosus rhodopsin orphan GPCR 0.0195 0.0124 0.0203
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0166 0.0103 0.0169
Mycobacterium leprae Probable guanylate kinase Gmk (GMP kinase). 0.0027 0.0003 0.0009
Leishmania major guanylate kinase, putative 0.0027 0.0003 0.0018
Echinococcus granulosus baculoviral IAP repeat containing protein 0.0107 0.0061 0.01
Loa Loa (eye worm) hypothetical protein 0.0041 0.0014 0.0034
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0166 0.0103 0.0256
Loa Loa (eye worm) hypothetical protein 0.0195 0.0124 0.0308
Echinococcus granulosus guanylate kinase 0.0027 0.0003 0.0005
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0054 0.0023 0.0038
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0139 0.0084 0.0138
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0638 0.0441 0.0441
Echinococcus granulosus Regulator of G protein signaling 20 0.0041 0.0014 0.0022
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0638 0.0441 0.0441
Echinococcus granulosus neuropeptides capa receptor 0.0195 0.0124 0.0203
Echinococcus granulosus biogenic amine 5HT receptor 0.0195 0.0124 0.0203
Brugia malayi tailless protein 0.0078 0.004 0.01
Loa Loa (eye worm) acetyltransferase 0.0151 0.0092 0.0231
Toxoplasma gondii ribonucleoside-diphosphate reductase large chain 0.2403 0.1707 1
Loa Loa (eye worm) hypothetical protein 0.0041 0.0014 0.0034
Brugia malayi G-protein coupled receptor 0.0195 0.0124 0.0308
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0195 0.0124 0.0308
Echinococcus granulosus sterol regulatory element binding protein 0.0529 0.0363 0.0599
Echinococcus granulosus rhodopsin orphan GPCR 0.0195 0.0124 0.0203
Toxoplasma gondii aspartyl protease ASP3 0.0638 0.0441 0.2584
Trypanosoma cruzi puromycin-sensitive aminopeptidase-like protein, putative 0.0049 0.0019 0.0112
Echinococcus multilocularis expressed protein 0.0404 0.0274 0.0451
Brugia malayi Regulator of G protein signaling domain containing protein 0.0041 0.0014 0.0034
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0166 0.0103 0.0103
Loa Loa (eye worm) hypothetical protein 0.0056 0.0024 0.006
Schistosoma mansoni zinc finger protein 0.0078 0.004 0.004
Trichomonas vaginalis calcium/calmodulin-dependent serine protein kinase membrane-associated guanylate kinase, putative 0.0027 0.0003 0.0021
Echinococcus multilocularis peripheral plasma membrane protein CASK 0.0033 0.0008 0.0013
Trichomonas vaginalis discs large, putative 0.0027 0.0003 0.0021
Loa Loa (eye worm) hypothetical protein 0.0195 0.0124 0.0308
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0195 0.0124 0.0124
Echinococcus granulosus tumor necrosis factor receptor superfamily 0.0044 0.0015 0.0025
Loa Loa (eye worm) hypothetical protein 0.0195 0.0124 0.0308
Onchocerca volvulus 0.0078 0.004 0.087
Schistosoma mansoni integrin alpha-ps 0.1114 0.0783 0.0783
Trichomonas vaginalis cyclin A, putative 0.0042 0.0014 0.0092
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0092 0.005 0.0291
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0054 0.0023 0.0134
Brugia malayi Latrophilin receptor protein 2 0.0449 0.0306 0.0764
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0079 0.0041 0.0272
Echinococcus multilocularis MAGUK p55 subfamily 0.0032 0.0007 0.0012
Trypanosoma cruzi cyclin 6, putative 0.0042 0.0014 0.008
Toxoplasma gondii aminopeptidase N, putative 0.0049 0.0019 0.0112
Echinococcus multilocularis apoptotic protease activating factor 1 0.0124 0.0073 0.012
Loa Loa (eye worm) hypothetical protein 0.0195 0.0124 0.0308
Loa Loa (eye worm) hypothetical protein 0.0088 0.0047 0.0117
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0078 0.004 0.01
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0088 0.0047 0.0047
Echinococcus granulosus ribonucleoside diphosphate reductase subunit 0.0135 0.0081 0.0133
Giardia lamblia Guanylate kinase 0.0027 0.0003 0.0075
Loa Loa (eye worm) hypothetical protein 0.0529 0.0363 0.0907
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0195 0.0124 0.0203
Schistosoma mansoni regulator of G protein signaling 0.0047 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0049 0.0019 0.0048
Echinococcus granulosus [G-protein-coupledreceptor] kinase 0.0113 0.0065 0.0107
Echinococcus granulosus regulator of G protein signaling 3 0.0041 0.0014 0.0022
Onchocerca volvulus 0.0195 0.0124 0.2771
Echinococcus granulosus g protein coupled receptor 0.0195 0.0124 0.0203
Trichomonas vaginalis conserved hypothetical protein 0.0079 0.0041 0.0272
Schistosoma mansoni cell polarity protein 0.0098 0.0054 0.0054
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0166 0.0103 0.0103
Loa Loa (eye worm) ribonucleotide reductase M2 B 0.0135 0.0081 0.0202
Brugia malayi ORL1-like opioid receptor 0.0195 0.0124 0.0308
Echinococcus multilocularis cyclin B 0.0042 0.0014 0.0023
Loa Loa (eye worm) hypothetical protein 0.0195 0.0124 0.0308
Loa Loa (eye worm) hypothetical protein 0.0195 0.0124 0.0308
Treponema pallidum ribonucleotide-diphosphate reductase subunit alpha 0.2403 0.1707 1
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0139 0.0084 0.0138
Loa Loa (eye worm) RGC/RGC protein kinase 0.0029 0.0005 0.0013
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0088 0.0047 0.0077
Mycobacterium ulcerans thymidine phosphorylase 0.5002 0.357 1
Echinococcus multilocularis ribonucleoside diphosphate reductase subunit 0.0135 0.0081 0.0133
Echinococcus multilocularis guanylate kinase 0.0027 0.0003 0.0005
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0139 0.0084 0.0138
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0529 0.0363 0.0907
Trypanosoma brucei proteasome beta 6 subunit 0.0054 0.0023 0.0134
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0078 0.004 0.004
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0045 0.0016 0.0093
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0088 0.0047 0.0047
Loa Loa (eye worm) steroid hormone receptor 0.0166 0.0103 0.0256
Plasmodium vivax aspartyl protease, putative 0.0638 0.0441 0.2584
Echinococcus multilocularis fmrfamide receptor 0.0195 0.0124 0.0203
Loa Loa (eye worm) hypothetical protein 0.0597 0.0412 0.1027
Echinococcus granulosus hypothetical protein 0.0195 0.0124 0.0203
Loa Loa (eye worm) hypothetical protein 0.0166 0.0103 0.0256
Echinococcus multilocularis somatostatin receptor 0.0195 0.0124 0.0203
Brugia malayi ribonucleotide reductase 2 0.0135 0.0081 0.0202
Trichomonas vaginalis cyclins, putative 0.0042 0.0014 0.0092
Echinococcus multilocularis aminopeptidase N 0.0474 0.0323 0.0533
Plasmodium falciparum plasmepsin IX 0.0638 0.0441 0.2584
Entamoeba histolytica hypothetical protein, conserved 0.0345 0.0231 1
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0041 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0041 0.0014 0.0034
Echinococcus multilocularis neuropeptide receptor A26 0.0195 0.0124 0.0203
Echinococcus multilocularis Peptidase M1, membrane alanine aminopeptidase, N terminal 0.0139 0.0084 0.0138
Loa Loa (eye worm) hypothetical protein 0.0024 0.0001 0.0003
Echinococcus granulosus peptidyl glycine alpha amidating monooxygenase 0.046 0.0313 0.0516
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0166 0.0103 0.0256
Schistosoma mansoni neuropeptide F-like receptor 0.0195 0.0124 0.0124
Loa Loa (eye worm) guanylate kinase 0.0032 0.0007 0.0018
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0151 0.0092 0.0152
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0166 0.0103 0.0256
Echinococcus granulosus g protein coupled receptor 0.0195 0.0124 0.0203
Loa Loa (eye worm) hypothetical protein 0.0195 0.0124 0.0308
Echinococcus granulosus beta-adrenergic receptor kinase 0.0123 0.0072 0.0119
Trypanosoma brucei ribonucleoside-diphosphate reductase large chain 0.2403 0.1707 1
Brugia malayi guanylate kinase 0.0027 0.0003 0.0008
Schistosoma mansoni integrin beta subunit 0.3284 0.2338 0.2338
Trichomonas vaginalis hypothetical protein 0.0048 0.0019 0.0125
Brugia malayi CHE-14 protein 0.0529 0.0363 0.0907
Loa Loa (eye worm) ribonucleoside-diphosphate reductase large subunit 0.2403 0.1707 0.4261
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.0049 0.0019 0.0128
Echinococcus granulosus thyroid hormone receptor alpha 0.0078 0.004 0.0066
Schistosoma mansoni inhibitor of apoptosis (iap) domain family member 0.0107 0.0061 0.0061
Onchocerca volvulus 0.0139 0.0084 0.1869
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0166 0.0103 0.0169
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0027 0.0004 0.0024
Echinococcus multilocularis rhodopsin orphan GPCR 0.0195 0.0124 0.0203
Echinococcus multilocularis serotonin receptor 0.0195 0.0124 0.0203
Echinococcus multilocularis 55 kDa erythrocyte membrane protein 0.0032 0.0007 0.0012
Trypanosoma cruzi metallo-peptidase, clan MA(E), family M1, putative 0.0049 0.0019 0.0112
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0166 0.0103 0.0103
Onchocerca volvulus 0.0195 0.0124 0.2771
Schistosoma mansoni serine/threonine protein kinase 0.0123 0.0072 0.0072
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0195 0.0124 0.0203
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0195 0.0124 0.0203
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0166 0.0103 0.0256
Echinococcus granulosus kelch ECH associated protein 1 like 0.073 0.0507 0.0835
Brugia malayi Copper type II ascorbate-dependent monooxygenase, C-terminal domain containing protein 0.012 0.007 0.0175
Schistosoma mansoni opsin-like receptor 0.0195 0.0124 0.0124
Echinococcus multilocularis caspase 3 0.0071 0.0035 0.0057
Brugia malayi nuclear hormone receptor family member odr-7 0.0078 0.004 0.01
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0166 0.0103 0.0169
Loa Loa (eye worm) voltage-dependent calcium channel beta 2a subunit 0.0027 0.0003 0.0008
Trypanosoma cruzi metallo-peptidase, clan MA(E), family M1, putative 0.0139 0.0084 0.0491
Echinococcus granulosus kelch ECH associated protein 1 like 0.073 0.0507 0.0835
Echinococcus multilocularis G-protein coupled receptor, putative 0.0195 0.0124 0.0203
Onchocerca volvulus 0.0092 0.005 0.1088
Trypanosoma brucei ribonucleoside-diphosphate reductase small chain 0.0135 0.0081 0.0473
Loa Loa (eye worm) hypothetical protein 0.0195 0.0124 0.0308
Loa Loa (eye worm) hypothetical protein 0.0078 0.004 0.01
Loa Loa (eye worm) hypothetical protein 0.0166 0.0103 0.0256
Echinococcus granulosus allatostatin A receptor 0.0333 0.0223 0.0367
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.1154 0.0811 0.1336
Trypanosoma cruzi metacaspase 5, putative 0.0079 0.0041 0.0237
Leishmania major ribonucleoside-diphosphate reductase large chain, putative 0.2403 0.1707 1
Brugia malayi Tachykinin-like peptides receptor 99D 0.0195 0.0124 0.0308
Schistosoma mansoni histamine h1 receptor 0.0195 0.0124 0.0124
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0078 0.004 0.087
Toxoplasma gondii cathepsin CPC2 0.017 0.0106 0.0618
Giardia lamblia Tenascin precursor 0.0133 0.008 0.1913
Entamoeba histolytica DNA repair protein RAD51, putative 0.0024 0.0001 0.005
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0014 0.0092
Entamoeba histolytica hypothetical protein 0.0041 0.0014 0.0589
Echinococcus multilocularis 0.0032 0.0007 0.0012
Echinococcus granulosus guanylate kinase 0.0027 0.0003 0.0005
Schistosoma mansoni hypothetical protein 0.0195 0.0124 0.0124
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0603 0.0416 0.0685
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0195 0.0124 0.0124
Schistosoma mansoni hypothetical protein 0.0092 0.005 0.005
Loa Loa (eye worm) hypothetical protein 0.0971 0.068 0.1697
Echinococcus multilocularis adam 0.0133 0.008 0.0131
Mycobacterium ulcerans ribonucleotide-diphosphate reductase subunit beta 0.0046 0.0017 0.0038
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0079 0.0041 0.0237
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.017 0.0106 0.0618
Schistosoma mansoni dopamine-beta-monooxygenase 0.0244 0.0159 0.0159
Loa Loa (eye worm) hypothetical protein 0.0133 0.008 0.0199
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0078 0.004 0.0066
Echinococcus granulosus c-Jun N-terminal kinases 0.0231 0.015 0.0246
Echinococcus granulosus g-protein coupled receptor 0.0195 0.0124 0.0203
Loa Loa (eye worm) rad51 0.0024 0.0001 0.0003
Echinococcus granulosus GPCR family 2 0.0449 0.0306 0.0504
Onchocerca volvulus Neuropeptide F receptor homolog 0.0195 0.0124 0.2771
Loa Loa (eye worm) hypothetical protein 0.0078 0.004 0.01
Leishmania major puromycin-sensitive aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 0.0049 0.0019 0.0112
Brugia malayi nuclear receptor NHR-67 0.0078 0.004 0.01
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0025 0.0002 0.0003
Trichomonas vaginalis meiosis-specific recA homolog Dmc1 0.0024 0.0001 0.0008
Loa Loa (eye worm) hypothetical protein 0.0088 0.0047 0.0117
Trypanosoma cruzi Aminopeptidase M1, putative 0.0139 0.0084 0.0491
Echinococcus granulosus axis inhibition protein axin 0.0041 0.0014 0.0022
Brugia malayi Voltage-dependent L-type calcium channel beta-2 subunit 0.0027 0.0003 0.0008
Brugia malayi Uncoordinated protein 44 0.0029 0.0004 0.0011
Plasmodium vivax plasmepsin V, putative 0.0638 0.0441 0.2584
Echinococcus multilocularis neuroendocrine convertase 2 0.0157 0.0097 0.0159
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0079 0.0041 0.0041
Brugia malayi acetyltransferase, GNAT family protein 0.0151 0.0092 0.0231
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0002 0.0012
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0059 0.0026 0.0177
Loa Loa (eye worm) hypothetical protein 0.0195 0.0124 0.0308
Brugia malayi EGF-like domain containing protein 0.0133 0.008 0.0199
Brugia malayi Melatonin receptor type 1A 0.0195 0.0124 0.0308
Plasmodium falciparum ribonucleoside-diphosphate reductase large subunit, putative 0.2403 0.1707 1
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0449 0.0306 0.0504
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0195 0.0124 0.0308
Echinococcus multilocularis replication protein A 70 kDa DNA binding 0.0039 0.0012 0.002
Plasmodium vivax aspartyl protease, putative 0.0638 0.0441 0.2584
Leishmania major CYC2-like cyclin, putative,cyclin 6, putative 0.0042 0.0014 0.008
Echinococcus multilocularis regulator of G protein signaling 7 0.0041 0.0014 0.0022
Brugia malayi hypothetical protein 0.0195 0.0124 0.0308
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0079 0.0041 0.0237
Echinococcus multilocularis integrin beta 2 0.4144 0.2955 0.4867
Loa Loa (eye worm) peptidase family M1 containing protein 0.0383 0.0259 0.0646
Loa Loa (eye worm) replication factor A 73 kDa subunit 0.0039 0.0012 0.003
Trypanosoma brucei metacaspase 0.0079 0.0041 0.0237
Loa Loa (eye worm) RGS-3 protein 0.0041 0.0014 0.0034
Loa Loa (eye worm) hypothetical protein 0.0041 0.0014 0.0034
Schistosoma mansoni hypothetical protein 0.0195 0.0124 0.0124
Loa Loa (eye worm) hypothetical protein 0.0166 0.0103 0.0256
Echinococcus multilocularis Furin 1 0.0059 0.0026 0.0043
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0059 0.0026 0.0177
Echinococcus multilocularis g protein coupled receptor 0.0195 0.0124 0.0203
Echinococcus multilocularis integrin alpha ps 0.1114 0.0783 0.1289
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0166 0.0103 0.0169
Loa Loa (eye worm) proteasome subunit beta type 1 0.0054 0.0023 0.0057
Echinococcus granulosus MAGUK p55 subfamily 0.0032 0.0007 0.0012
Echinococcus multilocularis inhibitor of apoptosis protein 0.0107 0.0061 0.01
Echinococcus multilocularis rhodopsin orphan GPCR 0.0195 0.0124 0.0203
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0195 0.0124 0.0124
Brugia malayi EGF-like domain containing protein 0.0133 0.008 0.0199
Wolbachia endosymbiont of Brugia malayi ribonucleotide-diphosphate reductase subunit alpha 0.2097 0.1487 1
Brugia malayi hypothetical protein 0.0124 0.0073 0.0181
Echinococcus granulosus nmda type glutamate receptor 0.0026 0.0003 0.0004
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.1154 0.0811 0.0811
Echinococcus multilocularis disks large 1 0.0027 0.0003 0.0005
Plasmodium falciparum plasmepsin VIII, putative 0.0638 0.0441 0.2584
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0025 0.0002 0.001
Giardia lamblia Proteasome subunit beta type 1 0.0054 0.0023 0.0551
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0078 0.004 0.0066
Loa Loa (eye worm) hypothetical protein 0.0078 0.004 0.01
Schistosoma mansoni aryl hydrocarbon receptor 0.0096 0.0053 0.0053
Echinococcus multilocularis beta adrenergic receptor kinase 0.0123 0.0072 0.0119
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0041 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0078 0.004 0.01
Echinococcus granulosus high voltage activated calcium channel beta 0.0027 0.0003 0.0005
Leishmania major cyclin 0.0042 0.0014 0.008
Echinococcus granulosus histone acetyltransferase KAT2B 0.0045 0.0016 0.0026
Echinococcus granulosus somatostatin receptor 0.0195 0.0124 0.0203
Loa Loa (eye worm) hypothetical protein 0.0195 0.0124 0.0308
Brugia malayi Protein kinase domain containing protein 0.003 0.0005 0.0013
Loa Loa (eye worm) hypothetical protein 0.0195 0.0124 0.0308
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0529 0.0363 0.0363
Loa Loa (eye worm) hypothetical protein 0.188 0.1332 0.3324
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0166 0.0103 0.0256
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0603 0.0416 0.0685
Loa Loa (eye worm) hypothetical protein 0.0049 0.0019 0.0048
Schistosoma mansoni cytosol alanyl aminopeptidase (M01 family) 0.0139 0.0084 0.0084
Plasmodium vivax plasmepsin IV, putative 0.1154 0.0811 0.4753
Entamoeba histolytica guanylate kinase, putative 0.0027 0.0003 0.0136
Echinococcus multilocularis FTZ F1 alpha 0.0166 0.0103 0.0169
Trypanosoma brucei guanylate kinase, putative 0.0027 0.0003 0.0018
Brugia malayi ecdysone receptor 0.0078 0.004 0.01
Echinococcus multilocularis G protein coupled receptor kinase 1 0.0082 0.0042 0.007
Brugia malayi Receptor family ligand binding region containing protein 0.0029 0.0005 0.0013
Loa Loa (eye worm) hypothetical protein 0.046 0.0313 0.0782
Trichomonas vaginalis adenylate cyclase, putative 0.0027 0.0004 0.0024
Loa Loa (eye worm) guanylate kinase 0.0081 0.0042 0.0105
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0195 0.0124 0.0124
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0195 0.0124 0.0308
Schistosoma mansoni ATP-dependent RNA Helicase 0.0032 0.0007 0.0007
Schistosoma mansoni regulator of G protein signaling 0.0041 0.0014 0.0014
Plasmodium falciparum plasmepsin X 0.0638 0.0441 0.2584
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.0056 0.0024 0.006
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.1573 0.1112 0.2775
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0166 0.0103 0.0169
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0054 0.0023 0.0154
Echinococcus multilocularis neuropeptide Y receptor 0.0195 0.0124 0.0203
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0041 0.0014 0.0022
Onchocerca volvulus 0.0474 0.0323 0.7321
Echinococcus granulosus Nuclear hormone receptor HR96 0.0078 0.004 0.0066
Onchocerca volvulus 0.0195 0.0124 0.2771
Echinococcus granulosus inhibitor of apoptosis protein 0.0107 0.0061 0.01
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.0139 0.0084 0.0564
Schistosoma mansoni amine GPCR 0.0195 0.0124 0.0124
Brugia malayi PXA domain containing protein 0.0041 0.0014 0.0034
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0019 0.0125
Loa Loa (eye worm) hypothetical protein 0.0029 0.0004 0.0011
Trichomonas vaginalis 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative 0.0603 0.0416 0.28
Schistosoma mansoni neuropeptide f receptor 76f 0.0195 0.0124 0.0124
Trypanosoma brucei metacaspase 5, putative 0.0079 0.0041 0.0237
Trichomonas vaginalis hypothetical protein 0.0133 0.008 0.0535
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0019 0.0125
Brugia malayi Steroid receptor seven-up type 2 0.0166 0.0103 0.0256
Trypanosoma cruzi metacaspase, putative 0.0079 0.0041 0.0237
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0078 0.004 0.087
Schistosoma mansoni neuropeptide F-like receptor 0.0195 0.0124 0.0124
Brugia malayi G-protein coupled receptor 0.0195 0.0124 0.0308
Echinococcus granulosus Furin 1 0.0059 0.0026 0.0043
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0638 0.0441 0.0441
Echinococcus granulosus G protein coupled receptor kinase 1 0.0082 0.0042 0.007
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0449 0.0306 0.0764
Brugia malayi hypothetical protein 0.086 0.06 0.1499
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0026 0.0002 0.0015
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.0056 0.0024 0.004
Echinococcus granulosus furin 0.025 0.0163 0.0269
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0149 0.0091 0.015
Schistosoma mansoni biogenic amine (5HT) receptor 0.0195 0.0124 0.0124
Plasmodium falciparum ribonucleoside-diphosphate reductase small chain, putative 0.0046 0.0017 0.0098
Brugia malayi Serotonin receptor 0.0195 0.0124 0.0308
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0166 0.0103 0.0256
Echinococcus granulosus FTZ F1 alpha 0.0166 0.0103 0.0169
Brugia malayi proprotein convertase 2 0.0157 0.0097 0.0241
Echinococcus granulosus 55 kDa erythrocyte membrane protein 0.0032 0.0007 0.0012
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0195 0.0124 0.0203
Trypanosoma cruzi guanylate kinase, putative 0.0027 0.0003 0.0018
Trichomonas vaginalis sap-102, putative 0.0027 0.0003 0.0021
Plasmodium falciparum proteasome subunit beta type-1, putative 0.0054 0.0023 0.0134
Giardia lamblia High cysteine membrane protein Group 2 0.0093 0.0051 0.1214
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0041 0.0014 0.0022
Echinococcus granulosus regulator of G protein signaling 7 0.0041 0.0014 0.0022
Brugia malayi Nuclear hormone receptor-like 1 0.0088 0.0047 0.0117
Brugia malayi endoprotease bli-4 precursor 0.025 0.0163 0.0407
Echinococcus multilocularis hydroxymethylglutaryl coenzyme A reductase 0.1286 0.0906 0.1492
Loa Loa (eye worm) hypothetical protein 0.0195 0.0124 0.0308
Giardia lamblia Tenascin-like 0.0133 0.008 0.1913
Trichomonas vaginalis cyclins, putative 0.0028 0.0004 0.0029
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0019 0.0125
Plasmodium vivax M1-family alanyl aminopeptidase, putative 0.0049 0.0019 0.0112
Onchocerca volvulus 0.0133 0.008 0.1772
Echinococcus multilocularis G protein coupled receptor 139 0.0195 0.0124 0.0203
Echinococcus granulosus disks large 1 0.0027 0.0003 0.0005
Echinococcus granulosus nuclear receptor nhr 48 0.0078 0.004 0.0066
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0079 0.0041 0.0237
Onchocerca volvulus 0.0638 0.0441 1
Toxoplasma gondii ribonucleoside-diphosphate reductase small subunit 0.0135 0.0081 0.0473
Brugia malayi putative neuropeptide receptor 0.0195 0.0124 0.0308
Brugia malayi hypothetical protein 0.0195 0.0124 0.0308
Brugia malayi AKH receptor 0.0195 0.0124 0.0308
Onchocerca volvulus 0.0195 0.0124 0.2771
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0014 0.0092
Echinococcus granulosus Niemann Pick C1 protein 0.0529 0.0363 0.0599
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0078 0.004 0.0066
Brugia malayi larval opioid receptor 0.0195 0.0124 0.0308
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0078 0.004 0.0066
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0019 0.0125
Trypanosoma cruzi aminopeptidase, putative 0.0049 0.0019 0.0112
Echinococcus multilocularis g protein coupled receptor 0.0195 0.0124 0.0203
Echinococcus multilocularis aryl hydrocarbon receptor 0.0025 0.0002 0.0003
Echinococcus granulosus disks large 3 0.0098 0.0054 0.0089
Trypanosoma brucei metacaspase MCA2 0.0079 0.0041 0.0237
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0027 0.0004 0.0024
Trichomonas vaginalis conserved hypothetical protein 0.0079 0.0041 0.0272
Leishmania major guanylate kinase-like protein 0.0027 0.0003 0.0018
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0014 0.0092
Echinococcus multilocularis G protein coupled receptor kinase 6 0.0113 0.0065 0.0107
Echinococcus multilocularis neuropeptide s receptor 0.0195 0.0124 0.0203
Plasmodium vivax ribonucleotide reductase small subunit, putative 0.0046 0.0017 0.0098
Loa Loa (eye worm) hypothetical protein 0.0029 0.0004 0.0011
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.0703 0.0488 0.0803
Schistosoma mansoni growth hormone secretagogue receptor 0.0195 0.0124 0.0124
Loa Loa (eye worm) hypothetical protein 0.0244 0.0159 0.0397
Echinococcus multilocularis GPCR, family 2 0.0449 0.0306 0.0504
Loa Loa (eye worm) hypothetical protein 0.0027 0.0003 0.0008
Loa Loa (eye worm) hypothetical protein 0.0195 0.0124 0.0308
Giardia lamblia G2/mitotic-specific cyclin B 0.0042 0.0014 0.033
Echinococcus multilocularis TNFR CD27 30 40 95 cysteine rich region 0.0044 0.0015 0.0025
Echinococcus granulosus high voltage activated calcium channel beta 0.0027 0.0003 0.0005
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0079 0.0041 0.0272
Plasmodium vivax aspartyl proteinase, putative 0.0638 0.0441 0.2584
Echinococcus multilocularis orexin receptor type 2 0.0195 0.0124 0.0203
Loa Loa (eye worm) hypothetical protein 0.0195 0.0124 0.0308
Plasmodium vivax ribonucleoside-diphosphate reductase large chain, putative 0.2403 0.1707 1
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0123 0.0072 0.018
Schistosoma mansoni caspase-7 (C14 family) 0.0342 0.0229 0.0229
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0166 0.0103 0.0103
Giardia lamblia 3-hydroxy-3-methylglutaryl-coenzyme A reductase 0.0603 0.0416 1
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0231 0.015 0.0246
Trichomonas vaginalis cyclins, putative 0.0042 0.0014 0.0092
Schistosoma mansoni maguk P55 subfamily member 26 0.0032 0.0007 0.0007
Leishmania major RAD51/dmc1 protein 0.0024 0.0001 0.0007
Loa Loa (eye worm) guanylate kinase 0.0027 0.0003 0.0008
Schistosoma mansoni nuclear receptor 0.0078 0.004 0.004
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0195 0.0124 0.0203
Plasmodium falciparum plasmepsin IV 0.1154 0.0811 0.4753
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0019 0.0125
Echinococcus granulosus replication protein A 70 kDa DNA binding 0.0039 0.0012 0.002
Schistosoma mansoni regulator of G protein signaling 0.0041 0.0014 0.0014
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.1154 0.0811 0.5455
Plasmodium falciparum plasmepsin VI 0.1154 0.0811 0.4753
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0166 0.0103 0.0169
Trichomonas vaginalis guanylate cyclase, putative 0.0027 0.0004 0.0024
Schistosoma mansoni amine GPCR 0.0195 0.0124 0.0124
Mycobacterium tuberculosis Probable ribonucleoside-diphosphate reductase (large subunit) NrdZ (ribonucleotide reductase) 0.0754 0.0524 0.1462
Brugia malayi hypothetical protein 0.0041 0.0014 0.0034
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0079 0.0041 0.0272
Leishmania major aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 0.0139 0.0084 0.0491
Echinococcus granulosus tm gpcr rhodopsin 0.849 0.6071 1
Loa Loa (eye worm) hypothetical protein 0.0195 0.0124 0.0308
Brugia malayi Peripheral plasma membrane protein CASK 0.0042 0.0014 0.0036
Brugia malayi hypothetical protein 0.0201 0.0128 0.032
Chlamydia trachomatis ribonucleoside-diphosphate reductase subunit alpha 0.2403 0.1707 1
Echinococcus granulosus cyclin B 0.0042 0.0014 0.0023
Brugia malayi Hydroxymethylglutaryl-coenzyme A reductase family protein 0.1286 0.0906 0.2261
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0025 0.0002 0.001
Echinococcus multilocularis serotonin receptor 0.0195 0.0124 0.0203
Loa Loa (eye worm) hypothetical protein 0.0321 0.0214 0.0534
Schistosoma mansoni thyroid hormone receptor 0.029 0.0192 0.0192
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0195 0.0124 0.0308
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0195 0.0124 0.0203
Brugia malayi hypothetical protein 0.0027 0.0003 0.0008
Entamoeba histolytica hypothetical protein 0.0201 0.0128 0.5533
Echinococcus granulosus TNFR CD27 30 40 95 cysteine rich region 0.0044 0.0015 0.0025
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0166 0.0103 0.0169
Echinococcus granulosus serotonin receptor 0.0195 0.0124 0.0203
Echinococcus multilocularis regulator of G protein signaling 3 0.0041 0.0014 0.0022
Echinococcus granulosus expressed protein 0.0404 0.0274 0.0451
Echinococcus granulosus epidermal growth factor receptor 0.006 0.0027 0.0044
Brugia malayi Guanylate kinase family protein 0.0027 0.0003 0.0008
Trypanosoma brucei metallo-peptidase, Clan MA(E) Family M1 0.0139 0.0084 0.0491
Loa Loa (eye worm) hypothetical protein 0.0133 0.008 0.0199
Onchocerca volvulus 0.0078 0.004 0.087
Plasmodium vivax aspartyl protease, putative 0.0638 0.0441 0.2584
Echinococcus multilocularis rhodopsin orphan GPCR 0.0195 0.0124 0.0203
Brugia malayi aspartic protease BmAsp-2, identical 0.0638 0.0441 0.1101
Schistosoma mansoni high voltage-activated calcium channel beta subunit 1 0.0027 0.0003 0.0003
Toxoplasma gondii meiotic recombination protein DMC1 family protein 0.0024 0.0001 0.0007
Brugia malayi hypothetical protein 0.0638 0.0441 0.1101
Echinococcus multilocularis peptidyl glycine alpha amidating monooxygenase 0.046 0.0313 0.0516
Echinococcus granulosus leukotriene A 4 hydrolase 0.0049 0.0019 0.0031
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0139 0.0084 0.0138
Loa Loa (eye worm) hypothetical protein 0.0195 0.0124 0.0308
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0166 0.0103 0.0256
Loa Loa (eye worm) hypothetical protein 0.0078 0.004 0.01
Trypanosoma brucei mitotic cyclin 6 0.0042 0.0014 0.008
Loa Loa (eye worm) hypothetical protein 0.0195 0.0124 0.0308
Brugia malayi nuclear hormone receptor family member nhr-6 0.0078 0.004 0.01
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0195 0.0124 0.0124
Loa Loa (eye worm) TATA binding protein associated factor 0.0049 0.0019 0.0048
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0195 0.0124 0.0203
Echinococcus granulosus Ankyrin 0.0029 0.0004 0.0007
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0019 0.0125
Echinococcus granulosus neuropeptide Y receptor 0.0195 0.0124 0.0203
Echinococcus granulosus neuropeptide s receptor 0.0195 0.0124 0.0203
Trypanosoma cruzi ribonucleoside-diphosphate reductase small chain, putative 0.0135 0.0081 0.0473
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0079 0.0041 0.0272
Echinococcus granulosus peripheral plasma membrane protein CASK 0.0033 0.0008 0.0013
Loa Loa (eye worm) hypothetical protein 0.0195 0.0124 0.0308
Plasmodium falciparum M1-family alanyl aminopeptidase, putative 0.0049 0.0019 0.0112
Brugia malayi Death domain containing protein 0.0029 0.0004 0.0011
Schistosoma mansoni cathepsin D (A01 family) 0.2472 0.1756 0.1756
Chlamydia trachomatis transcriptional repressor NrdR 0.0306 0.0203 0.1183
Wolbachia endosymbiont of Brugia malayi ribonucleotide-diphosphate reductase subunit beta 0.0135 0.0081 0.0523
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0054 0.0023 0.0134
Loa Loa (eye worm) lethal(1)discs large-1 tumor suppressor 0.0093 0.005 0.0125
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0166 0.0103 0.0256
Schistosoma mansoni family M1 non-peptidase homologue (M01 family) 0.009 0.0049 0.0049
Echinococcus multilocularis Ankyrin 0.0029 0.0004 0.0007
Onchocerca volvulus Putative replication factor A 73 kDa subunit 0.0035 0.0009 0.0165
Brugia malayi Copper type II ascorbate-dependent monooxygenase, C-terminal domain containing protein 0.046 0.0313 0.0782
Schistosoma mansoni hypothetical protein 0.0449 0.0306 0.0306
Echinococcus granulosus orexin receptor type 2 0.0195 0.0124 0.0203
Brugia malayi A-kinase anchor protein 10, precursor 0.0041 0.0014 0.0034
Loa Loa (eye worm) TK/EGFR protein kinase 0.006 0.0027 0.0067
Toxoplasma gondii aspartyl protease ASP1 0.1154 0.0811 0.4753
Echinococcus granulosus neuropeptide Y receptor 0.0195 0.0124 0.0203
Echinococcus granulosus neuroendocrine convertase 2 0.0157 0.0097 0.0159
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0201 0.0128 0.0211
Echinococcus multilocularis tachykinin peptides receptor 99D 0.077 0.0536 0.0882
Trichomonas vaginalis 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative 0.0603 0.0416 0.28
Loa Loa (eye worm) hypothetical protein 0.0166 0.0103 0.0256
Onchocerca volvulus 0.0195 0.0124 0.2771
Schistosoma mansoni serine-type protease inhibitor 0.2712 0.1928 0.1928
Brugia malayi Serotonin receptor 0.0195 0.0124 0.0308
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 0.0049 0.0019 0.0112
Echinococcus granulosus 7TM GPCR rhodopsin 0.0195 0.0124 0.0203
Trypanosoma brucei Metacaspase-4 0.0079 0.0041 0.0237
Schistosoma mansoni tumor necrosis factor receptor related 0.0044 0.0015 0.0015
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0638 0.0441 0.0441
Loa Loa (eye worm) hypothetical protein 0.0195 0.0124 0.0308
Schistosoma mansoni nuclear receptor nhr-48 0.0078 0.004 0.004
Loa Loa (eye worm) aminopeptidase N 0.0139 0.0084 0.0209
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0045 0.0016 0.0093
Brugia malayi Protein kinase domain containing protein 0.0093 0.005 0.0126
Loa Loa (eye worm) DR-78 0.0078 0.004 0.01
Echinococcus multilocularis caspase 0.0149 0.0091 0.015
Onchocerca volvulus 0.0195 0.0124 0.2771
Echinococcus granulosus regulator of G protein signaling 7 0.0041 0.0014 0.0022
Loa Loa (eye worm) hypothetical protein 0.0078 0.004 0.01
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0195 0.0124 0.0308
Brugia malayi orphan nuclear receptor NR2E1 0.0078 0.004 0.01
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0166 0.0103 0.0256
Trypanosoma cruzi ribonucleoside-diphosphate reductase small chain, putative 0.0135 0.0081 0.0473
Echinococcus multilocularis axis inhibition protein axin 0.0041 0.0014 0.0022
Schistosoma mansoni biogenic amine receptor 0.0195 0.0124 0.0124
Echinococcus granulosus axis inhibition protein axin 0.0041 0.0014 0.0022
Toxoplasma gondii aspartyl protease 0.0638 0.0441 0.2584
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0149 0.0091 0.015
Loa Loa (eye worm) hypothetical protein 0.0098 0.0054 0.0135
Onchocerca volvulus 0.0034 0.0009 0.0156
Loa Loa (eye worm) hypothetical protein 0.0166 0.0103 0.0256
Loa Loa (eye worm) hypothetical protein 0.0092 0.005 0.0124
Trichomonas vaginalis replication factor A 1, rfa1, putative 0.0037 0.0011 0.0071
Loa Loa (eye worm) hypothetical protein 0.0078 0.004 0.01
Brugia malayi hypothetical protein 0.0195 0.0124 0.0308
Brugia malayi Guanylate kinase family protein 0.0032 0.0007 0.0018
Trichomonas vaginalis replication factor A 1, rfa1, putative 0.0039 0.0012 0.008
Schistosoma mansoni hypothetical protein 0.0048 0.0019 0.0019
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0166 0.0103 0.0169
Loa Loa (eye worm) peripheral plasma membrane protein CASK 0.0032 0.0007 0.0018
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0195 0.0124 0.0124
Echinococcus granulosus Protein patched homolog 1 0.0529 0.0363 0.0599
Echinococcus multilocularis ecdysone induced protein 78C 0.0166 0.0103 0.0169
Echinococcus granulosus atrial natriuretic peptide receptor 0.0026 0.0003 0.0004
Schistosoma mansoni opsin-like receptor 0.0195 0.0124 0.0124
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0195 0.0124 0.0308
Echinococcus multilocularis rhodopsin orphan GPCR 0.0195 0.0124 0.0203
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0027 0.0004 0.0024
Trichomonas vaginalis conserved hypothetical protein 0.0079 0.0041 0.0272
Brugia malayi Dopamine receptor 0.0195 0.0124 0.0308
Loa Loa (eye worm) TYRA-2 protein 0.0195 0.0124 0.0308
Chlamydia trachomatis guanylate kinase 0.0027 0.0003 0.0008
Echinococcus granulosus neuropeptide FF receptor 2 0.0195 0.0124 0.0203
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0139 0.0084 0.0138
Loa Loa (eye worm) G-protein coupled receptor 0.0195 0.0124 0.0308
Loa Loa (eye worm) hypothetical protein 0.0166 0.0103 0.0256
Plasmodium vivax aspartyl proteinase, putative 0.1154 0.0811 0.4753
Plasmodium falciparum plasmepsin VII 0.0638 0.0441 0.2584
Toxoplasma gondii hypothetical protein 0.0133 0.008 0.0467
Giardia lamblia Neurogenic locus notch-like protein 0.0133 0.008 0.1913
Echinococcus granulosus caspase 3 0.0071 0.0035 0.0057
Loa Loa (eye worm) hypothetical protein 0.0041 0.0014 0.0034
Loa Loa (eye worm) hypothetical protein 0.0088 0.0047 0.0117
Brugia malayi Nuclear hormone receptor E75 0.0078 0.004 0.01
Echinococcus multilocularis dna repair protein rad51 1 0.0024 0.0001 0.0002
Echinococcus granulosus rhodopsin orphan GPCR 0.0195 0.0124 0.0203
Echinococcus multilocularis netrin receptor unc 5 0.0029 0.0004 0.0007
Loa Loa (eye worm) hypothetical protein 0.009 0.0049 0.0122
Echinococcus multilocularis fibrillin 2 0.0133 0.008 0.0131
Loa Loa (eye worm) hypothetical protein 0.0166 0.0103 0.0256
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0014 0.0092
Schistosoma mansoni Tata binding protein associated factor (M01 family) 0.0049 0.0019 0.0019
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0195 0.0124 0.0203
Echinococcus multilocularis epidermal growth factor receptor 0.006 0.0027 0.0044
Schistosoma mansoni tyrosine kinase 0.006 0.0027 0.0027
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0195 0.0124 0.0124
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0088 0.0047 0.0117
Mycobacterium leprae RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE (ALPHA CHAIN) NRDE (RIBONUCLEOTIDE REDUCTASE SMALL SUBUNIT) (R1F PROTEIN) 0.2097 0.1487 1
Brugia malayi nuclear receptor NHR-88 0.0166 0.0103 0.0256
Toxoplasma gondii kringle domain-containing protein 0.0092 0.005 0.0291
Leishmania major protein kinase, putative 0.0026 0.0002 0.0015
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0166 0.0103 0.0256
Echinococcus granulosus rhodopsin orphan GPCR 0.0195 0.0124 0.0203
Brugia malayi nuclear hormone receptor 0.0078 0.004 0.01
Brugia malayi celfurPC protein 0.0202 0.0129 0.0321
Trichomonas vaginalis conserved hypothetical protein 0.0529 0.0363 0.2444
Brugia malayi Kelch motif family protein 0.086 0.06 0.1499
Brugia malayi replication factor A 73 kDa subunit 0.0039 0.0012 0.003
Schistosoma mansoni single-minded 0.0096 0.0053 0.0053
Mycobacterium tuberculosis Probable anthranilate phosphoribosyltransferase TrpD 0.1412 0.0996 0.2784
Mycobacterium leprae conserved hypothetical protein 0.0345 0.0231 0.1545
Echinococcus multilocularis caspase 2 0.0342 0.0229 0.0377
Brugia malayi proteasome subunit beta type 1 0.0054 0.0023 0.0057
Echinococcus multilocularis neuropeptides capa receptor 0.0195 0.0124 0.0203
Echinococcus granulosus regulator of G protein signaling 3 0.0041 0.0014 0.0022
Echinococcus multilocularis fmrfamide receptor 0.0195 0.0124 0.0203
Trypanosoma cruzi guanylate kinase, putative 0.0027 0.0003 0.0018
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0026 0.0002 0.0015
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0139 0.0084 0.0138
Echinococcus granulosus adam 0.0133 0.008 0.0131
Brugia malayi regulator of G-protein signaling rgs-7 0.0041 0.0014 0.0034
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0029 0.0004 0.0007
Schistosoma mansoni maguk P55 subfamily member 35 0.0032 0.0007 0.0007
Trypanosoma cruzi metacaspase 5, putative 0.0079 0.0041 0.0237
Loa Loa (eye worm) hypothetical protein 0.0078 0.004 0.01
Brugia malayi hypothetical protein 0.0195 0.0124 0.0308
Schistosoma mansoni inhibitor of apoptosis protein 0.0107 0.0061 0.0061
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0195 0.0124 0.0124
Brugia malayi Integrin alpha cytoplasmic region family protein 0.188 0.1332 0.3324
Echinococcus granulosus integrin alpha ps 0.1114 0.0783 0.1289
Loa Loa (eye worm) hypothetical protein 0.0195 0.0124 0.0308
Trypanosoma cruzi 3-hydroxy-3-methylglutaryl-CoA reductase 0.1286 0.0906 0.5307
Schistosoma mansoni RAR-like nuclear receptor 0.0166 0.0103 0.0103
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0088 0.0047 0.0077
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0166 0.0103 0.0256
Loa Loa (eye worm) STAT protein 0.0312 0.0208 0.0518
Echinococcus granulosus rhodopsin orphan GPCR 0.0195 0.0124 0.0203
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0025 0.0002 0.0004
Echinococcus multilocularis regulator of G protein signaling 7 0.0041 0.0014 0.0022
Echinococcus multilocularis baculoviral IAP repeat containing protein 0.0107 0.0061 0.01
Schistosoma mansoni hypothetical protein 0.0449 0.0306 0.0306
Brugia malayi conserved hypotetical protein 0.0078 0.004 0.01
Echinococcus multilocularis sterol regulatory element binding protein 0.0529 0.0363 0.0599
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0195 0.0124 0.0124
Loa Loa (eye worm) hypothetical protein 0.0638 0.0441 0.1101
Trichomonas vaginalis guanylate cyclase, putative 0.0027 0.0004 0.0024
Echinococcus granulosus MAGUK p55 subfamily 0.0032 0.0007 0.0012
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0078 0.004 0.0066
Trypanosoma brucei Aminopeptidase M1, putative 0.0139 0.0084 0.0491
Trypanosoma cruzi metacaspase, putative 0.0079 0.0041 0.0237
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0027 0.0004 0.0024
Schistosoma mansoni guanylate kinase 0.0027 0.0003 0.0003
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0195 0.0124 0.0124
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0059 0.0026 0.0177
Echinococcus granulosus fibrillin 1 0.0133 0.008 0.0131
Loa Loa (eye worm) hypothetical protein 0.0195 0.0124 0.0308
Schistosoma mansoni hydroxymethylglutaryl-CoA reductase (NADPH) 0.1286 0.0906 0.0906
Brugia malayi Cyclin, N-terminal domain containing protein 0.0042 0.0014 0.0034
Mycobacterium ulcerans aminopeptidase N PepN 0.0139 0.0084 0.0226
Loa Loa (eye worm) hypothetical protein 0.0425 0.0288 0.072
Schistosoma mansoni thyroid hormone receptor 0.029 0.0192 0.0192
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0139 0.0084 0.0138
Loa Loa (eye worm) hypothetical protein 0.0195 0.0124 0.0308
Echinococcus granulosus integrin alpha ps 0.0534 0.0367 0.0604
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0079 0.0041 0.0272
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0107 0.0061 0.0151
Trypanosoma cruzi meiotic recombination protein DMC1, putative 0.0024 0.0001 0.0007
Schistosoma mansoni aminopeptidase A (M01 family) 0.0049 0.0019 0.0019
Schistosoma mansoni hypothetical protein 0.0449 0.0306 0.0306
Loa Loa (eye worm) hypothetical protein 0.0078 0.004 0.01
Echinococcus granulosus proprotein convertase subtilisin:kexin type 5 0.0152 0.0093 0.0153
Mycobacterium tuberculosis Conserved protein 0.0345 0.0231 0.064
Entamoeba histolytica hypothetical protein 0.0201 0.0128 0.5533
Giardia lamblia hypothetical protein 0.0133 0.008 0.1913
Trypanosoma brucei guanylate kinase, putative 0.0027 0.0003 0.0018
Schistosoma mansoni furin-1 (S08 family) 0.0109 0.0062 0.0062
Plasmodium falciparum plasmepsin III 0.0638 0.0441 0.2584
Onchocerca volvulus 0.0195 0.0124 0.2771
Entamoeba histolytica hypothetical protein 0.0041 0.0014 0.0589
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 0.0139 0.0084 0.0491
Schistosoma mansoni cathepsin D (A01 family) 0.2472 0.1756 0.1756
Echinococcus granulosus histone acetyltransferase KAT2B 0.0147 0.0089 0.0147
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0166 0.0103 0.0103
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0152 0.0093 0.0625
Brugia malayi hypothetical protein 0.0078 0.004 0.01
Trichomonas vaginalis neuroendocrine convertase 2 precursor, putative 0.0048 0.0019 0.0125
Onchocerca volvulus 0.0195 0.0124 0.2771
Mycobacterium tuberculosis Probable thymidine phosphorylase DeoA (tdrpase) (pyrimidine phosphorylase) 0.5002 0.357 1
Brugia malayi photoreceptor-specific nuclear receptor 0.0166 0.0103 0.0256
Brugia malayi Kringle domain containing protein 0.0092 0.005 0.0124
Brugia malayi Dopamine receptor protein 1 0.0195 0.0124 0.0308
Onchocerca volvulus 0.0107 0.0061 0.1338
Brugia malayi ribonucleoside-diphosphate reductase large chain, putative 0.2403 0.1707 0.4261
Brugia malayi latrophilin 2 splice variant baaae 0.0971 0.068 0.1697
Echinococcus granulosus fmrfamide receptor 0.0195 0.0124 0.0203
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0079 0.0041 0.0272
Brugia malayi EGF-like domain containing protein 0.0133 0.008 0.0199
Trypanosoma brucei 3-hydroxy-3-methylglutaryl-CoA reductase, putative 0.1286 0.0906 0.5307
Mycobacterium ulcerans hydroxymethylglutaryl-coenzyme a (HMG-CoA) reductase 0.1286 0.0906 0.2531
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0002 0.0012
Echinococcus granulosus single minded 2 0.0071 0.0035 0.0057
Echinococcus granulosus neuropeptide receptor 0.0195 0.0124 0.0203
Echinococcus multilocularis neuropeptide receptor 0.0195 0.0124 0.0203
Loa Loa (eye worm) TK/ROR protein kinase 0.0093 0.005 0.0126
Loa Loa (eye worm) kelch domain-containing protein family protein 0.086 0.06 0.1499
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.017 0.0106 0.0618
Brugia malayi Calcitonin receptor-like protein seb-1 0.142 0.1002 0.2501
Echinococcus granulosus caspase 2 0.0342 0.0229 0.0377
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0333 0.0223 0.0223
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0195 0.0124 0.0308
Echinococcus multilocularis tumor necrosis factor receptor superfamily 0.0044 0.0015 0.0025
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0195 0.0124 0.0203
Echinococcus granulosus caspase 0.0149 0.0091 0.015
Toxoplasma gondii aminopeptidase N protein 0.0049 0.0019 0.0112
Onchocerca volvulus 0.0333 0.0223 0.5028
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0045 0.0016 0.0093
Loa Loa (eye worm) hypothetical protein 0.0342 0.0229 0.0571
Brugia malayi ZU5 domain containing protein 0.0027 0.0003 0.0008
Schistosoma mansoni neuropeptide receptor 0.0195 0.0124 0.0124
Echinococcus multilocularis transfer RNA-Lys 0.0071 0.0035 0.0057
Toxoplasma gondii proteasome subunit beta type 1, putative 0.0054 0.0023 0.0134
Leishmania major hypothetical protein, conserved 0.0092 0.005 0.0291
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0166 0.0103 0.0169
Echinococcus granulosus dna repair protein rad51 1 0.0024 0.0001 0.0002
Trichomonas vaginalis leucine-rich repeat protein, BspA family 0.0048 0.0019 0.0125
Trypanosoma brucei RNA helicase, putative 0.0109 0.0062 0.0363
Loa Loa (eye worm) nuclear hormone receptor 0.0078 0.004 0.01
Brugia malayi neuropeptide F receptor 0.0195 0.0124 0.0308
Echinococcus multilocularis rhodopsin orphan GPCR 0.0195 0.0124 0.0203
Echinococcus multilocularis thymidine phosphorylase 0.5002 0.357 0.5881
Loa Loa (eye worm) hypothetical protein 0.0195 0.0124 0.0308
Schistosoma mansoni serine-type protease inhibitor 0.2712 0.1928 0.1928
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0638 0.0441 0.0441
Trypanosoma brucei Aminopeptidase M1, putative 0.0139 0.0084 0.0491
Plasmodium falciparum metacaspase 1 0.0079 0.0041 0.0237
Echinococcus granulosus receptor type guanylyl cyclase 0.0029 0.0005 0.0008
Loa Loa (eye worm) G protein-coupled receptor kinase 1 0.0113 0.0065 0.0162
Schistosoma mansoni amine GPCR 0.0195 0.0124 0.0124
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0154 0.0095 0.0236
Schistosoma mansoni steroid hormone receptor ad4bp 0.0166 0.0103 0.0103
Loa Loa (eye worm) aspartic protease BmAsp-2 0.1154 0.0811 0.2025
Schistosoma mansoni caspase-3 (C14 family) 0.0149 0.0091 0.0091
Echinococcus granulosus peptide allatostatin:somatostatin 0.0195 0.0124 0.0203
Onchocerca volvulus Protein ultraspiracle homolog 0.0166 0.0103 0.2298
Loa Loa (eye worm) hypothetical protein 0.086 0.06 0.1499
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0026 0.0002 0.0015
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0078 0.004 0.004
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0026 0.0003 0.0004
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0195 0.0124 0.0203
Brugia malayi TATA binding protein associated factor 0.0049 0.0019 0.0048
Echinococcus multilocularis sex peptide receptor 0.0195 0.0124 0.0203
Loa Loa (eye worm) integrin beta-2 0.561 0.4006 1
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0002 0.0012
Schistosoma mansoni amine GPCR 0.0195 0.0124 0.0124
Plasmodium falciparum metacaspase-like protein 0.0079 0.0041 0.0237
Loa Loa (eye worm) hypothetical protein 0.1951 0.1383 0.3451
Echinococcus granulosus neuropeptides capa receptor 0.0195 0.0124 0.0203
Plasmodium vivax proteasome subunit beta type-1, putative 0.0054 0.0023 0.0134
Brugia malayi steroid hormone receptor 0.0166 0.0103 0.0256
Onchocerca volvulus Deterin homolog 0.0107 0.0061 0.1338
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0195 0.0124 0.0124
Trypanosoma cruzi puromycin-sensitive aminopeptidase-like protein, putative 0.0049 0.0019 0.0112
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0195 0.0124 0.0124
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0152 0.0093 0.0093
Brugia malayi hypothetical protein 0.0139 0.0084 0.0209
Echinococcus multilocularis Regulator of G protein signaling 20 0.0041 0.0014 0.0022
Loa Loa (eye worm) hypothetical protein 0.0195 0.0124 0.0308
Echinococcus granulosus biogenic amine 5HT receptor 0.0195 0.0124 0.0203
Brugia malayi Pepsin A precursor 0.0638 0.0441 0.1101
Loa Loa (eye worm) hypothetical protein 0.0032 0.0007 0.0018
Echinococcus multilocularis neuropeptide Y receptor 0.0195 0.0124 0.0203
Brugia malayi regulator of G-protein signaling egl-10 0.0041 0.0014 0.0034
Brugia malayi hypothetical protein 0.0041 0.0014 0.0034
Echinococcus granulosus netrin receptor unc 5 0.0029 0.0004 0.0007
Brugia malayi hypothetical protein 0.0088 0.0047 0.0117
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0195 0.0124 0.0124
Trypanosoma cruzi CYC2-like cyclin, putative 0.0042 0.0014 0.008
Mycobacterium ulcerans transcriptional regulator NrdR 0.0306 0.0203 0.0562
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0079 0.0041 0.0272
Echinococcus granulosus neuropeptide receptor 0.0195 0.0124 0.0203
Toxoplasma gondii aminopeptidase n, putative 0.0049 0.0019 0.0112
Schistosoma mansoni axis inhibition protein axin 0.0041 0.0014 0.0014
Loa Loa (eye worm) integrin alpha pat-2 0.3831 0.273 0.6815
Loa Loa (eye worm) hypothetical protein 0.0133 0.008 0.0199
Echinococcus granulosus ribonucleoside diphosphate reductase large 0.2403 0.1707 0.2812
Schistosoma mansoni nuclear hormone receptor 0.0078 0.004 0.004
Brugia malayi STAT protein, DNA binding domain containing protein 0.0312 0.0208 0.0518
Plasmodium falciparum cysteine repeat modular protein 1 0.0092 0.005 0.0291
Brugia malayi Integrin alpha pat-2 precursor 0.2485 0.1766 0.4407
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0124 0.0073 0.012
Mycobacterium ulcerans putative regulatory protein 0.0071 0.0035 0.0089
Brugia malayi hypothetical protein 0.0321 0.0214 0.0534
Loa Loa (eye worm) hypothetical protein 0.0195 0.0124 0.0308
Brugia malayi abnormal cell lineage protein 2 0.0027 0.0003 0.0008
Onchocerca volvulus 0.0195 0.0124 0.2771
Echinococcus multilocularis tissue type plasminogen activator 0.0092 0.005 0.0082
Echinococcus multilocularis neuropeptides capa receptor 0.0195 0.0124 0.0203
Plasmodium falciparum plasmepsin I 0.1154 0.0811 0.4753
Onchocerca volvulus 0.0195 0.0124 0.2771
Mycobacterium tuberculosis Probable transcriptional regulatory protein NrdR 0.0306 0.0203 0.0562
Brugia malayi hypothetical protein 0.0195 0.0124 0.0308
Giardia lamblia High cysteine protein 0.0133 0.008 0.1913
Trypanosoma cruzi cyclin, putative 0.0042 0.0014 0.008
Entamoeba histolytica hypothetical protein 0.0201 0.0128 0.5533
Plasmodium vivax hypothetical protein, conserved 0.0079 0.0041 0.0237
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0019 0.0125
Loa Loa (eye worm) hypothetical protein 0.0042 0.0014 0.0034
Echinococcus multilocularis protein jagged 2 0.0133 0.008 0.0131
Loa Loa (eye worm) hypothetical protein 0.0333 0.0223 0.0556
Onchocerca volvulus 0.0195 0.0124 0.2771
Schistosoma mansoni hypothetical protein 0.0201 0.0128 0.0128
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0195 0.0124 0.0308
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0195 0.0124 0.0124
Echinococcus multilocularis rhodopsin orphan GPCR 0.0195 0.0124 0.0203
Plasmodium falciparum guanylate kinase 0.0027 0.0003 0.0018
Loa Loa (eye worm) hypothetical protein 0.1286 0.0906 0.2261
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0139 0.0084 0.0138
Schistosoma mansoni cyclin B 0.0042 0.0014 0.0014
Schistosoma mansoni opsin-like receptor 0.0195 0.0124 0.0124
Loa Loa (eye worm) hypothetical protein 0.0124 0.0073 0.0181
Loa Loa (eye worm) hypothetical protein 0.1154 0.0811 0.2025
Echinococcus granulosus integrin beta 2 0.4144 0.2955 0.4867
Trypanosoma cruzi 3-hydroxy-3-methylglutaryl-CoA reductase, putative 0.1286 0.0906 0.5307
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0113 0.0065 0.0162
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0166 0.0103 0.0169
Echinococcus multilocularis regulator of G protein signaling 3 0.0041 0.0014 0.0022
Trypanosoma brucei ribonucleoside-diphosphate reductase small chain, putative 0.0135 0.0081 0.0473
Brugia malayi PAS domain containing protein 0.0096 0.0053 0.0131
Brugia malayi Cyclin, N-terminal domain containing protein 0.0042 0.0014 0.0034
Mycobacterium tuberculosis Ribonucleoside-diphosphate reductase (beta chain) NrdF1 (ribonucleotide reductase small subunit) (R2F protein) 0.0135 0.0081 0.0218
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.1154 0.0811 0.4753
Echinococcus granulosus integrin alpha 3 0.1905 0.135 0.2223
Brugia malayi Peptidase family M1 containing protein 0.0139 0.0084 0.0209
Leishmania major ribonucleoside-diphosphate reductase small chain, putative 0.0135 0.0081 0.0473

Activities

Activity type Activity value Assay description Source Reference
MIC (functional) = 1.56 ug ml-1 In vitro antibacterial activity for minimum inhibition concentration (MIC) required to inhibit growth of Staphylococcus aureus ChEMBL. 6363698

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

No external resources registered for this compound

Bibliographic References

1 literature reference was collected for this gene.

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