Detailed information for compound 1278421

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 467.599 | Formula: C24H41N3O6
  • H donors: 3 H acceptors: 5 LogP: 3.04 Rotable bonds: 13
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCC([C@@H](C(=O)O)NC(=O)[C@@H]1CC[C@H](CC1)CNC(=O)[C@@H]1CCCN1C(=O)OC(C)(C)C)C
  • InChi: 1S/C24H41N3O6/c1-6-15(2)19(22(30)31)26-20(28)17-11-9-16(10-12-17)14-25-21(29)18-8-7-13-27(18)23(32)33-24(3,4)5/h15-19H,6-14H2,1-5H3,(H,25,29)(H,26,28)(H,30,31)/t15?,16-,17-,18-,19-/m0/s1
  • InChiKey: FPGCWHRLVNLPSA-WNBKYALVSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Escherichia coli penicillin-binding protein Starlite/ChEMBL No references
Homo sapiens GNAS complex locus Starlite/ChEMBL No references
Homo sapiens polymerase (DNA directed), beta Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative Get druggable targets OG5_130965 All targets in OG5_130965
Mycobacterium ulcerans hypothetical protein Get druggable targets OG5_130965 All targets in OG5_130965
Echinococcus granulosus guanine nucleotide binding protein Gs subunit Get druggable targets OG5_131088 All targets in OG5_131088
Leishmania mexicana mitochondrial DNA polymerase beta Get druggable targets OG5_130965 All targets in OG5_130965
Mycobacterium tuberculosis Possible penicillin-binding protein Get druggable targets OG5_149948 All targets in OG5_149948
Schistosoma japonicum ko:K04632 guanine nucleotide binding protein (G protein), alpha stimulating, putative Get druggable targets OG5_131088 All targets in OG5_131088
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Leishmania braziliensis mitochondrial DNA polymerase beta Get druggable targets OG5_130965 All targets in OG5_130965
Leishmania major mitochondrial DNA polymerase beta Get druggable targets OG5_130965 All targets in OG5_130965
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative Get druggable targets OG5_130965 All targets in OG5_130965
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative Get druggable targets OG5_131088 All targets in OG5_131088
Leishmania infantum mitochondrial DNA polymerase beta Get druggable targets OG5_130965 All targets in OG5_130965
Echinococcus granulosus guanine nucleotide binding protein Gs subunit Get druggable targets OG5_131088 All targets in OG5_131088
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain Get druggable targets OG5_131088 All targets in OG5_131088
Trypanosoma brucei mitochondrial DNA polymerase beta Get druggable targets OG5_130965 All targets in OG5_130965
Trypanosoma congolense mitochondrial DNA polymerase beta, putative Get druggable targets OG5_130965 All targets in OG5_130965
Trypanosoma brucei gambiense mitochondrial DNA polymerase beta Get druggable targets OG5_130965 All targets in OG5_130965
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit Get druggable targets OG5_131088 All targets in OG5_131088
Leishmania donovani mitochondrial DNA polymerase beta Get druggable targets OG5_130965 All targets in OG5_130965
Mycobacterium tuberculosis Conserved hypothetical protein Get druggable targets OG5_130965 All targets in OG5_130965
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit Get druggable targets OG5_131088 All targets in OG5_131088
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative polymerase (DNA directed), beta 335 aa 303 aa 32.3 %
Schistosoma mansoni GTP-binding protein alpha subunit gna GNAS complex locus 394 aa 450 aa 28.7 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0187 0.0357 0.0445
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0187 0.0357 0.1735
Schistosoma mansoni pcd6 interacting protein-related 0.0095 0.0164 0.0209
Echinococcus granulosus thioredoxin glutathione reductase 0.0099 0.0172 0.0168
Schistosoma mansoni hypothetical protein 0.004 0.0048 0.0061
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0036 0.0039 0.01
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0811 0.1667 0.4275
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.0038 0.0049
Echinococcus multilocularis phosphatidylinositol 4 kinase alpha 0.0187 0.0357 0.0353
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0021 0.0008 0.0093
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0095 0.0164 0.0199
Brugia malayi Importin beta-1 subunit 0.0062 0.0095 0.0111
Mycobacterium tuberculosis Conserved protein 0.0043 0.0055 0.0699
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0095 0.0164 0.0199
Plasmodium vivax phosphatidylinositol 3-kinase, putative 0.0187 0.0357 1
Loa Loa (eye worm) hypothetical protein 0.0037 0.0042 0.0043
Onchocerca volvulus 0.0095 0.0164 0.2992
Loa Loa (eye worm) PHD-finger family protein 0.0023 0.0013 0.0006
Trichomonas vaginalis glucosylceramidase, putative 0.0293 0.0578 0.2365
Echinococcus granulosus TRP transient receptor potential channel 0.0036 0.0039 0.0035
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0241 0.0471 0.059
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0036 0.0039 0.0161
Trypanosoma cruzi inositol 1,4,5-trisphosphate receptor, putative 0.0036 0.0039 0.01
Loa Loa (eye worm) hypothetical protein 0.0041 0.0051 0.0055
Echinococcus multilocularis potassium voltage gated channel protein 0.0036 0.0039 0.0035
Echinococcus multilocularis FTZ F1 alpha 0.0021 0.0008 0.0004
Entamoeba histolytica hypothetical protein 0.0035 0.0038 0.0138
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0034 0.0036 0.0148
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0624 0.1274 0.3267
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0973 0.2007 0.5315
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0036 0.0039 0.005
Brugia malayi hypothetical protein 0.0095 0.0164 0.0199
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0035 0.0038 0.0426
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0325 0.0646 1
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0036 0.0039 0.0035
Echinococcus granulosus FTZ F1 alpha 0.0021 0.0008 0.0004
Entamoeba histolytica phosphatidylinositol-4,5-bisphosphate 3-kinase, putative 0.0187 0.0357 0.1735
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0039 0.0045 0.0191
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0095 0.0164 0.0199
Trichomonas vaginalis PIKK family atypical protein kinase 0.0611 0.1248 0.5154
Schistosoma mansoni hypothetical protein 0.0667 0.1365 0.1738
Leishmania major hypothetical protein, unknown function 0.0187 0.0357 0.0946
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0173 0.0326 0.0837
Echinococcus granulosus potassium voltage gated channel protein 0.0036 0.0039 0.0035
Leishmania major protein-tyrosine phosphatase 1-like protein 0.0095 0.0164 0.0434
Onchocerca volvulus 0.0035 0.0038 0.0648
Trichomonas vaginalis PIKK family atypical protein kinase 0.0973 0.2007 0.8317
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0225 0.0437 0.6557
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0054 0.0078 0.01
Schistosoma mansoni hypothetical protein 0.0035 0.0038 0.0049
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0072 0.0116 0.0112
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0036 0.0039 0.0039
Schistosoma mansoni hypothetical protein 0.0023 0.0013 0.0016
Schistosoma mansoni fkbp-rapamycin associated protein 0.0549 0.1116 0.1421
Schistosoma mansoni voltage-gated potassium channel 0.0036 0.0039 0.005
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0095 0.0164 0.0199
Trypanosoma cruzi tyrosine specific protein phosphatase, putative 0.0095 0.0164 0.042
Schistosoma mansoni cpg binding protein 0.0039 0.0045 0.0058
Loa Loa (eye worm) hypothetical protein 0.0549 0.1116 0.1412
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0187 0.0357 0.0915
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0187 0.0357 0.1443
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0187 0.0357 0.0455
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0039 0.0045 0.2345
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0011 0.0045
Schistosoma mansoni protein tyrosine phosphatase 0.0095 0.0164 0.0209
Trypanosoma brucei trypanothione reductase 0.0099 0.0171 0.071
Plasmodium falciparum importin beta, putative 0.0062 0.0095 0.2441
Trichomonas vaginalis PIKK family atypical protein kinase 0.0973 0.2007 0.8317
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0055 0.008 0.0091
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0095 0.0164 0.016
Toxoplasma gondii FATC domain-containing protein 0.0811 0.1667 0.8299
Leishmania major 4-coumarate:coa ligase-like protein 0.005 0.0069 0.0182
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0035 0.0038 0.0426
Brugia malayi AMP-binding enzyme family protein 0.005 0.0069 0.0077
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.3757 0.7852 0.7852
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0095 0.0164 0.0199
Echinococcus multilocularis serine protein kinase ATM 0.0811 0.1667 0.1664
Echinococcus granulosus two pore calcium channel protein 1 0.0036 0.0039 0.0035
Echinococcus granulosus transient receptor potential cation channel 0.0036 0.0039 0.0035
Trichomonas vaginalis PIKK family atypical protein kinase 0.0973 0.2007 0.8317
Trichomonas vaginalis glucosylceramidase, putative 0.0202 0.0389 0.1575
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0035 0.0038 0.0137
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0187 0.0357 0.0353
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0973 0.2007 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0054 0.0078 0.01
Schistosoma mansoni hypothetical protein 0.004 0.0048 0.0061
Trichomonas vaginalis inositol monophosphatase, putative 0.0039 0.0045 0.0144
Echinococcus multilocularis receptor type tyrosine protein phosphatase zeta 0.0095 0.0164 0.016
Schistosoma mansoni 60S ribosomal protein L21 0.0036 0.0039 0.005
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0811 0.1667 0.6916
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0036 0.0039 0.005
Schistosoma mansoni transient receptor potential channel 4 0.0036 0.0039 0.005
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0036 0.0039 0.0039
Echinococcus granulosus phosphatidylinositol 3 kinase catalytic subunit 0.0187 0.0357 0.0353
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0035 0.0038 0.0426
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0036 0.0039 0.0035
Schistosoma mansoni calcium channel voltage-dependent p/q type alpha 1a-related 0.0036 0.0039 0.005
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0095 0.0164 0.0199
Loa Loa (eye worm) hypothetical protein 0.0095 0.0164 0.0199
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0095 0.0164 0.0199
Loa Loa (eye worm) hypothetical protein 0.0095 0.0164 0.0199
Mycobacterium ulcerans lipase LipD 0.0043 0.0055 0.0247
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0973 0.2007 0.5145
Echinococcus multilocularis expressed conserved protein 0.0091 0.0155 0.0151
Loa Loa (eye worm) hypothetical protein 0.0036 0.0039 0.0039
Loa Loa (eye worm) hypothetical protein 0.0036 0.0039 0.0039
Onchocerca volvulus Glucosylceramidase homolog 0.0192 0.0367 0.677
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0011 0.0045
Giardia lamblia Phosphoinositide-3-kinase, class 3 0.0187 0.0357 0.1735
Entamoeba histolytica hypothetical protein 0.0187 0.0357 0.1735
Echinococcus multilocularis ryanodine receptor 44f 0.0036 0.0039 0.0035
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0043 0.0055 0.006
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0095 0.0164 0.0199
Plasmodium falciparum phosphatidylinositol 4-kinase 0.0187 0.0357 1
Brugia malayi beta-lactamase 0.0043 0.0055 0.006
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0053 0.0076 0.1881
Brugia malayi Ryanodine Receptor TM 4-6 family protein 0.0036 0.0039 0.0039
Schistosoma mansoni voltage-gated potassium channel 0.0036 0.0039 0.005
Onchocerca volvulus 0.0095 0.0164 0.2992
Brugia malayi olfactory channel protein osm-9 0.0036 0.0039 0.0039
Mycobacterium tuberculosis Probable lipase LipD 0.0043 0.0055 0.0699
Loa Loa (eye worm) phosphatidylinositol 3 0.0187 0.0357 0.0445
Schistosoma mansoni voltage-gated potassium channel 0.0036 0.0039 0.005
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.1875 0.3901 1
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0095 0.0164 0.0199
Trypanosoma brucei protein tyrosine phosphatase 1 0.0095 0.0164 0.068
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0095 0.0164 0.016
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0036 0.0039 0.005
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0034 0.0036 0.0035
Loa Loa (eye worm) hypothetical protein 0.0095 0.0164 0.0199
Giardia lamblia Histone acetyltransferase GCN5 0.0038 0.0045 0.017
Loa Loa (eye worm) hypothetical protein 0.0036 0.0039 0.0039
Loa Loa (eye worm) hypothetical protein 0.0469 0.0948 0.1199
Schistosoma mansoni voltage-gated potassium channel 0.0036 0.0039 0.005
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0095 0.0164 0.016
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0665 0.1361 0.5626
Leishmania major phosphatidylinositol kinase related protein, putative 0.045 0.0908 0.2406
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.1875 0.3901 0.3898
Echinococcus multilocularis transient receptor potential cation channel 0.0036 0.0039 0.0035
Loa Loa (eye worm) hypothetical protein 0.005 0.007 0.0078
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0034 0.0036 0.0095
Schistosoma mansoni protein-tyrosine phosphatase n9 0.0095 0.0164 0.0209
Loa Loa (eye worm) hypothetical protein 0.0049 0.0067 0.0075
Trypanosoma brucei phosphatidylinositol 4-kinase alpha, putative 0.0187 0.0357 0.1481
Trichomonas vaginalis conserved hypothetical protein 0.0362 0.0723 0.2968
Schistosoma mansoni protein tyrosine phosphatase 0.0095 0.0164 0.0209
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0187 0.0357 0.1735
Trichomonas vaginalis glucosylceramidase, putative 0.0293 0.0578 0.2365
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0027 0.0021 0.0027
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0021 0.0008 0.001
Entamoeba histolytica phosphatidylinositol 3-kinase 3, putative 0.0187 0.0357 0.1735
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0036 0.0039 0.0039
Echinococcus multilocularis receptor type tyrosine protein phosphatase protein tyrosine phosphatase receptor type 0.0095 0.0164 0.016
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0095 0.0164 0.0199
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0095 0.0164 0.016
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0008 0.0004
Echinococcus multilocularis hyperpolarization activated cyclic 0.0036 0.0039 0.0035
Loa Loa (eye worm) hypothetical protein 0.0036 0.0039 0.0039
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0095 0.0164 0.016
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0973 0.2007 0.8324
Trichomonas vaginalis PIKK family atypical protein kinase 0.0549 0.1116 0.4606
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0055 0.008 0.0076
Loa Loa (eye worm) protein-tyrosine phosphatase 0.3757 0.7852 1
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0036 0.0039 0.0035
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0034 0.0036 0.0032
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0036 0.0092
Loa Loa (eye worm) hypothetical protein 0.0187 0.0357 0.0445
Echinococcus multilocularis transient receptor potential cation channel 0.0036 0.0039 0.0035
Trichomonas vaginalis PIKK family atypical protein kinase 0.0973 0.2007 0.8317
Echinococcus granulosus muscleblind protein 0.0469 0.0948 0.0945
Echinococcus granulosus ryanodine receptor 44f 0.0036 0.0039 0.0035
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0034 0.0036 0.0726
Echinococcus multilocularis dna polymerase kappa 0.0022 0.0011 0.0007
Schistosoma mansoni nuclear hormone receptor 0.0021 0.0008 0.001
Echinococcus granulosus potassium voltage gated channel protein 0.0036 0.0039 0.0035
Trichomonas vaginalis glucosylceramidase, putative 0.0192 0.0367 0.1485
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0973 0.2007 0.8324
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0051 0.0072 0.0184
Brugia malayi AMP-binding enzyme family protein 0.005 0.0069 0.0077
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0035 0.0038 0.0048
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0549 0.1116 0.1412
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0036 0.0039 0.0035
Brugia malayi RNA, U transporter 1 0.0178 0.0337 0.0419
Toxoplasma gondii histone lysine methyltransferase SET1 0.0073 0.0118 0.0535
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0095 0.0164 0.0199
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0036 0.0039 0.0035
Giardia lamblia Phosphatidylinositol 4-kinase 0.0187 0.0357 0.1735
Loa Loa (eye worm) hypothetical protein 0.0036 0.0039 0.0039
Echinococcus multilocularis transient receptor potential gamma protein 0.0036 0.0039 0.0035
Mycobacterium tuberculosis Conserved hypothetical protein 0.0187 0.0357 0.5446
Toxoplasma gondii transporter, cation channel family protein 0.0036 0.0039 0.0142
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0034 0.0036 0.0046
Onchocerca volvulus 0.0187 0.0357 0.6583
Echinococcus multilocularis DNA dependent protein kinase catalytic subunit 0.478 1 1
Leishmania major phosphatidylinositol 3-kinase, putative 0.0187 0.0357 0.0946
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.004 0.0049 0.0044
Schistosoma mansoni importin beta-1 0.0062 0.0095 0.0121
Loa Loa (eye worm) hypothetical protein 0.0095 0.0164 0.0199
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.0038 0.0034
Mycobacterium tuberculosis Conserved protein 0.0043 0.0055 0.0699
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.1165 0.2411 1
Onchocerca volvulus 0.0095 0.0164 0.2992
Mycobacterium ulcerans beta-lactamase 0.0043 0.0055 0.0247
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0036 0.0039 0.005
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0021 0.0008 0.0004
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0187 0.0357 0.0455
Loa Loa (eye worm) CXXC zinc finger family protein 0.0035 0.0037 0.0036
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit gamma, putative 0.0187 0.0357 0.1443
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0095 0.0164 0.016
Schistosoma mansoni voltage-gated potassium channel 0.0036 0.0039 0.005
Onchocerca volvulus Protein ultraspiracle homolog 0.0021 0.0008 0.0093
Trypanosoma cruzi DNA polymerase eta, putative 0.0022 0.0011 0.0028
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0095 0.0164 0.016
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0189 0.0361 0.045
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0187 0.0357 0.0353
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0053 0.0076 0.0326
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0034 0.0036 0.0139
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0036 0.0092
Schistosoma mansoni voltage-gated potassium channel 0.0036 0.0039 0.005
Plasmodium vivax acyl-CoA synthetase, putative 0.0037 0.0042 0.0911
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0022 0.0011 0.0014
Loa Loa (eye worm) hypothetical protein 0.0037 0.0042 0.0043
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0022 0.0011 0.0007
Echinococcus multilocularis shaker cognate 0.0036 0.0039 0.0035
Loa Loa (eye worm) hypothetical protein 0.0095 0.0164 0.0199
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0189 0.0361 0.046
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0045 0.012
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0225 0.0437 0.6697
Brugia malayi hypothetical protein 0.0095 0.0164 0.0199
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0053 0.0076 1
Loa Loa (eye worm) hypothetical protein 0.0062 0.0095 0.0111
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0095 0.0164 0.0199
Loa Loa (eye worm) ion channel NompC 0.0036 0.0039 0.0039
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0053 0.0076 0.1021
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0095 0.0164 0.0209
Loa Loa (eye worm) hypothetical protein 0.0022 0.0011 0.0003
Onchocerca volvulus 0.0095 0.0164 0.2992
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0022 0.0011 0.0007
Mycobacterium tuberculosis Conserved protein 0.0043 0.0055 0.0699
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0036 0.0039 0.0118
Brugia malayi hypothetical protein 0.0095 0.0164 0.0199
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0011 0.0027
Echinococcus granulosus short transient receptor potential channel 6 0.0036 0.0039 0.0035
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0036 0.0039 0.005
Entamoeba histolytica acyl-CoA synthetase, putative 0.005 0.0069 0.0291
Trypanosoma cruzi trypanothione reductase, putative 0.0099 0.0171 0.0439
Schistosoma mansoni thyroid hormone receptor 0.0021 0.0008 0.001
Loa Loa (eye worm) hypothetical protein 0.0192 0.0368 0.0459
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0034 0.0036 0.0726
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0187 0.0357 0.0445
Echinococcus granulosus transient receptor potential cation channel 0.0036 0.0039 0.0035
Echinococcus multilocularis potassium voltage gated channel subfamily C 0.0036 0.0039 0.0035
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0187 0.0357 1
Brugia malayi Protein-tyrosine phosphatase 0.0095 0.0164 0.0199
Entamoeba histolytica Pten 3-phosphoinositide phosphatase, putative 0.0095 0.0164 0.0768
Loa Loa (eye worm) glutaminase 2 0.0879 0.181 0.2297
Echinococcus multilocularis transient receptor potential cation channel 0.0036 0.0039 0.0035
Brugia malayi Voltage-gated calcium channel, alpha subunit 0.0036 0.0039 0.0039
Leishmania major hypothetical protein, conserved 0.0036 0.0039 0.0103
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0021 0.0008 0.0004
Trichomonas vaginalis mercuric reductase, putative 0.0034 0.0036 0.0105
Echinococcus granulosus phosphatidylinositol 45 bisphosphate 3 kinase 0.0187 0.0357 0.0353
Plasmodium vivax hypothetical protein, conserved 0.0187 0.0357 1
Loa Loa (eye worm) phosphatidylinositol kinase 0.0187 0.0357 0.0445
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0187 0.0357 0.1443
Loa Loa (eye worm) hypothetical protein 0.0095 0.0164 0.0199
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0043 0.0055 0.0699
Echinococcus multilocularis Niemann Pick C1 protein 0.0097 0.0167 0.0163
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0095 0.0164 0.016
Trichomonas vaginalis PIKK family atypical protein kinase 0.0973 0.2007 0.8317
Echinococcus multilocularis importin subunit beta 1 0.0062 0.0095 0.0091
Loa Loa (eye worm) hypothetical protein 0.0036 0.0039 0.0039
Echinococcus multilocularis thioredoxin glutathione reductase 0.0099 0.0172 0.0168
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0008 0.0004
Entamoeba histolytica hypothetical protein 0.0035 0.0038 0.0138
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0665 0.1361 0.5626
Toxoplasma gondii peptidylprolyl isomerase 0.0032 0.0031 0.0103
Loa Loa (eye worm) phosphatidylinositol 3 0.0187 0.0357 0.0445
Trypanosoma cruzi phosphatidylinositol kinase, putative 0.0187 0.0357 0.0915
Onchocerca volvulus 4.1 G protein, putative homolog 0.0095 0.0164 0.2992
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0095 0.0164 0.0199
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0043 0.0055 0.0699
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0095 0.0164 0.0199
Schistosoma mansoni transient receptor potential channel 0.0036 0.0039 0.005
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0095 0.0164 0.016
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0036 0.0039 0.0118
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0034 0.0036 0.0726
Trichomonas vaginalis PIKK family atypical protein kinase 0.0973 0.2007 0.8317
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0034 0.0036 0.0095
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0095 0.0164 0.016
Echinococcus granulosus beta LACTamase domain containing family member 0.0043 0.0055 0.0051
Trichomonas vaginalis D-aminoacylase, putative 0.0043 0.0055 0.0186
Trypanosoma brucei hypothetical protein, conserved 0.0053 0.0076 0.0314
Schistosoma mansoni voltage-gated potassium channel 0.0036 0.0039 0.005
Schistosoma mansoni methyl-cpg binding protein mbd 0.0019 0.0004 0.0005
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0095 0.0164 0.016
Trichomonas vaginalis bromodomain-containing protein, putative 0.0045 0.0057 0.0195
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0036 0.0039 0.0039
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0095 0.0164 0.0199
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0039 0.0045 0.0173
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0036 0.0039 0.0035
Onchocerca volvulus 0.0043 0.0055 0.0969
Onchocerca volvulus 0.0095 0.0164 0.2992
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0187 0.0357 0.1481
Schistosoma mansoni hypothetical protein 0.0525 0.1067 0.1359
Entamoeba histolytica hypothetical protein 0.0035 0.0038 0.0138
Loa Loa (eye worm) hypothetical protein 0.0624 0.1274 0.1614
Loa Loa (eye worm) hypothetical protein 0.0036 0.0039 0.0039
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0187 0.0357 0.0915
Trichomonas vaginalis PIKK family atypical protein kinase 0.0973 0.2007 0.8317
Brugia malayi ion channel NompC 0.0036 0.0039 0.0039
Schistosoma mansoni protein-tyrosine phosphatase non-receptor type nt5 0.0095 0.0164 0.0209
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0036 0.0039 0.0035
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0551 0.1122 0.1118
Echinococcus multilocularis beta LACTamase domain containing family member 0.0043 0.0055 0.0051
Echinococcus multilocularis two pore calcium channel protein 2 0.0036 0.0039 0.0035
Echinococcus multilocularis Zinc finger, PHD finger 0.0187 0.0357 0.0353
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0036 0.0039 0.0035
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0022 0.0011 0.0044
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0036 0.0039 0.005
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0187 0.0357 0.1443
Plasmodium falciparum acyl-CoA synthetase 0.0037 0.0042 0.0911
Loa Loa (eye worm) hypothetical protein 0.0036 0.0039 0.0039
Echinococcus granulosus serine protein kinase ATM 0.0811 0.1667 0.1664
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0187 0.0357 0.1735
Loa Loa (eye worm) hypothetical protein 0.0043 0.0054 0.0059
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0011 0.0045
Schistosoma mansoni voltage-gated potassium channel 0.0036 0.0039 0.005
Schistosoma mansoni hypothetical protein 0.0187 0.0357 0.0455
Echinococcus multilocularis conserved hypothetical protein 0.0036 0.0039 0.0035
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0095 0.0164 0.016
Echinococcus granulosus sterol regulatory element binding protein 0.0041 0.0051 0.0047
Echinococcus granulosus zinc finger protein 0.0027 0.0022 0.0017
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0021 0.0008 0.0004
Schistosoma mansoni hypothetical protein 0.004 0.0048 0.0061
Schistosoma mansoni receptor protein tyrosine phosphatase r (pcptp1) 0.0095 0.0164 0.0209
Echinococcus granulosus shaker cognate 0.0036 0.0039 0.0035
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0665 0.1361 0.5626
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0011 0.0027
Mycobacterium tuberculosis Probable oxidoreductase 0.025 0.0489 0.7527
Onchocerca volvulus 0.0095 0.0164 0.2992
Onchocerca volvulus 0.0021 0.0008 0.0093
Plasmodium falciparum glutathione reductase 0.0099 0.0171 0.4634
Leishmania major hypothetical protein, unknown function 0.0036 0.0039 0.0103
Entamoeba histolytica hypothetical protein 0.0035 0.0038 0.0138
Echinococcus granulosus histone acetyltransferase KAT2B 0.0138 0.0254 0.025
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1715 0.3565 0.3562
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0225 0.0437 0.6697
Brugia malayi Bromodomain containing protein 0.0089 0.0152 0.0183
Echinococcus multilocularis potassium voltage gated channel protein 0.0036 0.0039 0.0035
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0095 0.0164 0.0199
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0095 0.0164 0.016
Echinococcus multilocularis expressed protein 0.0033 0.0033 0.0029
Trichomonas vaginalis glucosylceramidase, putative 0.0202 0.0389 0.1575
Echinococcus multilocularis protein patched 0.0041 0.0051 0.0047
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0025 0.0017 0.0011
Loa Loa (eye worm) hypothetical protein 0.0095 0.0164 0.0199
Echinococcus granulosus hypothetical protein 0.0036 0.0039 0.0035
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0008 0.0004
Leishmania major trypanothione reductase 0.0099 0.0171 0.0453
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.1875 0.3901 0.4962
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0021 0.0008 0.0004
Brugia malayi Protein-tyrosine phosphatase 1 0.0095 0.0164 0.0199
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.0549 0.1116 0.1112
Mycobacterium tuberculosis Probable dehydrogenase 0.0225 0.0437 0.6697
Loa Loa (eye worm) hypothetical protein 0.0036 0.0039 0.0039
Loa Loa (eye worm) phosphatidylinositol 3 0.0187 0.0357 0.0445
Echinococcus granulosus receptor type tyrosine protein phosphatase zeta 0.0095 0.0164 0.016
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0095 0.0164 0.0199
Trichomonas vaginalis penicillin-binding protein, putative 0.0043 0.0055 0.0186
Trichomonas vaginalis PIKK family atypical protein kinase 0.1165 0.2411 1
Loa Loa (eye worm) protein-tyrosine phosphatase 1 0.0095 0.0164 0.0199
Echinococcus granulosus potassium voltage gated channel protein 0.0036 0.0039 0.0035
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0051 0.0072 0.0184
Schistosoma mansoni two-pore calcium channel 0.0036 0.0039 0.005
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0033 0.0093
Echinococcus granulosus voltage dependent calcium channel 0.0036 0.0039 0.0035
Schistosoma mansoni rgs-gaip interacting protein gipc 0.0095 0.0164 0.0209
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0187 0.0357 0.0915
Loa Loa (eye worm) hypothetical protein 0.0095 0.0164 0.0199
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0611 0.1248 0.5175
Loa Loa (eye worm) protein-tyrosine-phosphatase 0.0095 0.0164 0.0199
Brugia malayi PHD-finger family protein 0.0033 0.0034 0.0033
Trichomonas vaginalis PIKK family atypical protein kinase 0.0187 0.0357 0.1443
Echinococcus granulosus voltage gated hydrogen channel 1 0.0036 0.0039 0.0035
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0054 0.0078 0.0074
Mycobacterium ulcerans acyl-CoA synthetase 0.005 0.0069 0.0321
Loa Loa (eye worm) hypothetical protein 0.0095 0.0164 0.0199
Trichomonas vaginalis PIKK family atypical protein kinase 0.0973 0.2007 0.8317
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0011 0.0045
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0036 0.0039 0.0035
Brugia malayi hypothetical protein 0.0036 0.0039 0.0039
Entamoeba histolytica hypothetical protein 0.0811 0.1667 0.8299
Loa Loa (eye worm) hypothetical protein 0.0036 0.0039 0.0039
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0021 0.0008 0.001
Loa Loa (eye worm) hypothetical protein 0.0036 0.0039 0.0039
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0187 0.0357 0.1443
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0665 0.1361 0.5626
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0011 0.0045
Trichomonas vaginalis PIKK family atypical protein kinase 0.0973 0.2007 0.8317
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0036 0.0039 0.0035
Schistosoma mansoni receptor protein tyrosine phosphatase 0.0095 0.0164 0.0209
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0187 0.0357 0.1443
Trypanosoma brucei hypothetical protein, conserved 0.0043 0.0055 0.0229
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0325 0.0646 0.3533
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0187 0.0357 0.1481
Brugia malayi Niemann-Pick C1 protein precursor 0.0097 0.0167 0.0202
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0095 0.0164 0.0768
Echinococcus multilocularis inositol monophosphatase 1 0.0039 0.0045 0.0041
Echinococcus multilocularis receptor type tyrosine protein phosphatase H 0.0095 0.0164 0.016
Giardia lamblia DINP protein human, muc B family 0.0022 0.0011 0.0001
Plasmodium vivax glutathione reductase, putative 0.0099 0.0171 0.4634
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0225 0.0437 0.6697
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0022 0.0011 0.0003
Echinococcus multilocularis receptor type tyrosine protein phosphatase zeta 0.0095 0.0164 0.016
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0973 0.2007 1
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0187 0.0357 0.0353
Echinococcus granulosus dna polymerase eta 0.0022 0.0011 0.0007
Trichomonas vaginalis PIKK family atypical protein kinase 0.0973 0.2007 0.8317
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0036 0.0039 0.0664
Loa Loa (eye worm) hypothetical protein 0.005 0.0069 0.0077
Brugia malayi hypothetical protein 0.0095 0.0164 0.0199
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0036 0.0039 0.0035
Schistosoma mansoni protein tyrosine phosphatase non-receptor type nt1 0.3757 0.7852 1
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0095 0.0164 0.0209
Echinococcus multilocularis potassium large conductance calcium activated 0.0036 0.0039 0.0035
Loa Loa (eye worm) hypothetical protein 0.0095 0.0164 0.0199
Trichomonas vaginalis PIKK family atypical protein kinase 0.0973 0.2007 0.8317
Echinococcus granulosus short transient receptor potential channel 6 0.0036 0.0039 0.0035
Leishmania major DNA polymerase eta, putative 0.0022 0.0011 0.0029
Trypanosoma brucei DNA polymerase IV, putative 0.0022 0.0011 0.0045
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0187 0.0357 0.0353
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0293 0.0578 0.0727
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0036 0.0039 0.0035
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0053 0.0076 0.0326
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0036 0.0039 0.005
Trichomonas vaginalis conserved hypothetical protein 0.0424 0.0855 0.3517
Echinococcus multilocularis L aminoadipate semialdehyde 0.0189 0.0361 0.0357
Trichomonas vaginalis PIKK family atypical protein kinase 0.0811 0.1667 0.6902
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0036 0.0039 0.005
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.0741 0.152 0.7562
Mycobacterium leprae conserved hypothetical protein 0.0053 0.0076 0.0641
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0187 0.0357 0.1481
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0036 0.0039 0.0035
Schistosoma mansoni inositol monophosphatase 0.0039 0.0045 0.0058
Echinococcus multilocularis ecdysone induced protein 78C 0.0021 0.0008 0.0004
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0187 0.0357 0.1735
Loa Loa (eye worm) hypothetical protein 0.0424 0.0855 0.1079
Loa Loa (eye worm) hypothetical protein 0.0189 0.0361 0.045
Loa Loa (eye worm) hypothetical protein 0.0053 0.0076 0.0086
Schistosoma mansoni zinc finger protein 0.0027 0.0022 0.0027
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0365 0.073 0.1871
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0973 0.2007 0.8324
Echinococcus multilocularis cpg binding protein 0.0039 0.0045 0.0041
Brugia malayi voltage-dependent calcium channel 0.0036 0.0039 0.0039
Loa Loa (eye worm) pigment dispersing factor receptor c 0.005 0.007 0.0078
Trichomonas vaginalis PIKK family atypical protein kinase 0.0973 0.2007 0.8317
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0187 0.0357 0.0915
Brugia malayi Muscleblind-like protein 0.0469 0.0948 0.1199
Trypanosoma cruzi hypothetical protein, conserved 0.0043 0.0055 0.0142
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0095 0.0164 0.0199
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0973 0.2007 0.5315
Trichomonas vaginalis D-aminoacylase, putative 0.0043 0.0055 0.0186
Onchocerca volvulus 0.0095 0.0164 0.2992
Leishmania major mitochondrial DNA polymerase beta 0.0365 0.073 0.1933
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0034 0.0036 0.0139
Trichomonas vaginalis PIKK family atypical protein kinase 0.0973 0.2007 0.8317
Giardia lamblia Phosphoinositide-3-kinase, catalytic, alpha polypeptide 0.0187 0.0357 0.1735
Trypanosoma brucei phosphatidylinositol 3-kinase catalytic subunit, putative 0.0187 0.0357 0.1481
Toxoplasma gondii target of rapamycin (TOR), putative 0.0973 0.2007 1
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0036 0.0039 0.0039
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0055 0.008 0.0076
Echinococcus multilocularis voltage gated potassium channel 0.0036 0.0039 0.0035
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0095 0.0164 0.0209
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0095 0.0164 0.016
Onchocerca volvulus 0.0095 0.0164 0.2992
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0365 0.073 0.3027
Trichomonas vaginalis set domain proteins, putative 0.0275 0.0541 0.2208
Loa Loa (eye worm) hypothetical protein 0.0095 0.0164 0.0199
Mycobacterium ulcerans hypothetical protein 0.005 0.0069 0.0321
Entamoeba histolytica hypothetical protein 0.0187 0.0357 0.1735
Entamoeba histolytica hypothetical protein 0.0187 0.0357 0.1735
Plasmodium falciparum phosphatidylinositol 3-kinase 0.0187 0.0357 1
Echinococcus multilocularis dna polymerase eta 0.0022 0.0011 0.0007
Schistosoma mansoni ran 0.0022 0.0011 0.0014
Trypanosoma cruzi phosphatidylinositol 3-kinase vps34-like 0.0187 0.0357 0.0915
Plasmodium vivax hypothetical protein 0.0187 0.0357 1
Echinococcus granulosus hyperpolarization activated cyclic 0.0036 0.0039 0.0035
Echinococcus granulosus Receptor type tyrosine protein phosphatase O 0.0095 0.0164 0.016
Echinococcus granulosus receptor type tyrosine protein phosphatase zeta 0.0095 0.0164 0.016
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0021 0.0008 0.001
Plasmodium falciparum histone acetyltransferase GCN5 0.0038 0.0045 0.0979
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0665 0.1361 0.6765
Toxoplasma gondii NADPH-glutathione reductase 0.0034 0.0036 0.0126
Trypanosoma brucei importin beta-1 subunit, putative 0.0062 0.0095 0.0395
Schistosoma mansoni transient receptor potential channel 0.0036 0.0039 0.005
Loa Loa (eye worm) hypothetical protein 0.0054 0.0078 0.0089
Trichomonas vaginalis phosphatidylinositol 4-kinase, putative 0.0187 0.0357 0.1443
Schistosoma mansoni methyl-cpg binding protein mbd 0.0019 0.0004 0.0005
Loa Loa (eye worm) inositol-1 0.0039 0.0045 0.0047
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0032 0.0031 0.013
Trichomonas vaginalis D-aminoacylase, putative 0.0043 0.0055 0.0186
Leishmania major 4-coumarate:coa ligase-like protein 0.005 0.0069 0.0182
Loa Loa (eye worm) hypothetical protein 0.0095 0.0164 0.0199
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0034 0.0036 0.0392
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0034 0.0036 0.0139
Loa Loa (eye worm) calcium channel 0.0036 0.0039 0.0039
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0187 0.0357 0.0915
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0011 0.0045
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0973 0.2007 0.2556
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0811 0.1667 0.2123
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0187 0.0357 0.0445
Trypanosoma brucei DNA polymerase eta, putative 0.0022 0.0011 0.0045
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0021 0.0008 0.0004
Brugia malayi cation channel family protein 0.0036 0.0039 0.0039
Trypanosoma cruzi tyrosine specific protein phosphatase, putative 0.0095 0.0164 0.042
Loa Loa (eye worm) protein tyrosine phosphatase 0.0095 0.0164 0.0199
Brugia malayi Transient-receptor-potential like protein 0.0036 0.0039 0.0039
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0011 0.0045
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0973 0.2007 0.5315
Schistosoma mansoni hypothetical protein 0.004 0.0048 0.0061
Entamoeba histolytica protein kinase rad3, putative 0.0549 0.1116 0.5538
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0033 0.0033 0.0031
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.005 0.0069 0.0525
Trypanosoma brucei unspecified product 0.0022 0.0011 0.0045
Echinococcus granulosus Niemann Pick C1 protein 0.0097 0.0167 0.0163
Mycobacterium ulcerans acyl-CoA synthetase 0.005 0.0069 0.0321
Loa Loa (eye worm) hypothetical protein 0.0036 0.0039 0.0039
Echinococcus granulosus potassium large conductance calcium activated 0.0036 0.0039 0.0035
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0022 0.0011 0.0003
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0055 0.008 0.0076
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.0038 0.0034
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0055 0.008 0.0102
Schistosoma mansoni steroid hormone receptor ad4bp 0.0021 0.0008 0.001
Schistosoma mansoni ran 0.0022 0.0011 0.0014
Loa Loa (eye worm) dual specificity protein phosphatase CDC14B 0.0095 0.0164 0.0199
Entamoeba histolytica hypothetical protein 0.0053 0.0076 0.0326
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0036 0.0039 0.005
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0187 0.0357 0.1443
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0095 0.0164 0.016
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0021 0.0008 0.0004
Mycobacterium ulcerans fatty-acid-CoA ligase 0.005 0.0069 0.0321
Toxoplasma gondii non-specific serine/threonine protein kinase 0.0611 0.1248 0.6197
Trichomonas vaginalis glutaminase, putative 0.0879 0.181 0.7497
Onchocerca volvulus 0.0095 0.0164 0.2992
Echinococcus granulosus serine:threonine protein kinase SMG1 0.0549 0.1116 0.1112
Loa Loa (eye worm) phosphatidylinositol 3 0.0187 0.0357 0.0445
Loa Loa (eye worm) phosphatidylinositol 4-kinase type 3 alpha isoform 1 0.0187 0.0357 0.0445
Echinococcus granulosus Receptor type tyrosine protein phosphatase O 0.0095 0.0164 0.016
Schistosoma mansoni hypothetical protein 0.0424 0.0855 0.1088
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0095 0.0164 0.016
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0365 0.073 0.1871
Leishmania major phosphatidylinositol 3-related kinase, putative 0.1165 0.2411 0.6385
Toxoplasma gondii hypothetical protein 0.0036 0.0039 0.0142
Onchocerca volvulus 0.0095 0.0164 0.2992
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0036 0.0092
Brugia malayi glutathione reductase 0.0099 0.0171 0.0208
Onchocerca volvulus 0.0043 0.0055 0.0969
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0549 0.1116 0.2861
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0021 0.0008 0.001
Mycobacterium ulcerans glutaminase 0.0879 0.181 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0973 0.2007 0.8317
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0034 0.0036 0.0095
Leishmania major phosphatidylinositol 4-kinase alpha, putative 0.0187 0.0357 0.0946
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0973 0.2007 0.8324
Loa Loa (eye worm) hypothetical protein 0.0036 0.0039 0.0039
Echinococcus multilocularis transfer RNA-Gly 0.0036 0.0039 0.0035
Loa Loa (eye worm) hypothetical protein 0.0095 0.0164 0.0199
Trichomonas vaginalis glucosylceramidase, putative 0.0192 0.0367 0.1485
Schistosoma mansoni terminal deoxycytidyl transferase 0.0022 0.0011 0.0014
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0036 0.0039 0.0039
Schistosoma mansoni cpg binding protein 0.0039 0.0045 0.0058
Loa Loa (eye worm) voltage-gated potassium channel 0.0036 0.0039 0.0039
Trypanosoma cruzi hypothetical protein, conserved 0.1628 0.3383 0.8672
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0187 0.0357 0.0455
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0187 0.0357 0.1735
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0053 0.0076 1
Loa Loa (eye worm) hypothetical protein 0.0469 0.0948 0.1199
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0022 0.0011 0.0007
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0187 0.0357 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0665 0.1361 0.5626
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0095 0.0164 0.0209
Trichomonas vaginalis PIKK family atypical protein kinase 0.0973 0.2007 0.8317
Schistosoma mansoni voltage-gated potassium channel 0.0036 0.0039 0.005
Onchocerca volvulus 0.0275 0.0541 1
Loa Loa (eye worm) hypothetical protein 0.0036 0.0039 0.0039
Echinococcus granulosus potassium voltage gated channel subfamily A 0.0036 0.0039 0.0035
Brugia malayi Pre-SET motif family protein 0.0035 0.0038 0.0038
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0095 0.0164 0.016
Echinococcus granulosus phosphatidylinositol 4 kinase beta 0.0187 0.0357 0.0353
Onchocerca volvulus 0.0095 0.0164 0.2992
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0043 0.0055 0.006
Schistosoma mansoni glutaminase 0.0879 0.181 0.2305
Schistosoma mansoni voltage-gated potassium channel 0.0036 0.0039 0.005
Plasmodium vivax phosphatidylinositol 3- and 4-kinase, putative 0.0187 0.0357 1
Loa Loa (eye worm) hypothetical protein 0.0034 0.0036 0.0036
Echinococcus multilocularis transient receptor potential cation channel 0.0036 0.0039 0.0035
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0036 0.0039 0.0035
Loa Loa (eye worm) hypothetical protein 0.0036 0.0039 0.0039
Loa Loa (eye worm) phosphatidylinositol 3 0.0187 0.0357 0.0445
Loa Loa (eye worm) hypothetical protein 0.0036 0.0039 0.0039
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0036 0.0039 0.005
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.0095 0.0164 0.0209
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0035 0.0038 0.0034
Trichomonas vaginalis PIKK family atypical protein kinase 0.0973 0.2007 0.8317
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0053 0.0076 0.0361
Echinococcus granulosus hyperpolarization activated cyclic 0.0036 0.0039 0.0035
Loa Loa (eye worm) glutathione reductase 0.0099 0.0171 0.0208
Echinococcus granulosus potassium voltage gated channel subfamily C 0.0036 0.0039 0.0035
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0021 0.0008 0.001
Trichomonas vaginalis PIKK family atypical protein kinase 0.0973 0.2007 0.8317
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0034 0.0036 0.0092
Echinococcus multilocularis muscleblind protein 1 0.0469 0.0948 0.0945
Brugia malayi Inositol-1 0.0039 0.0045 0.0047
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0095 0.0164 0.016
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0027 0.0021 0.0017
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0072 0.0116 0.0112
Brugia malayi beta-lactamase family protein 0.0043 0.0055 0.006
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0665 0.1361 0.5626
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0095 0.0164 0.0199
Trichomonas vaginalis rotamase, putative 0.0033 0.0033 0.0093
Trypanosoma brucei DNA polymerase IV, putative 0.0022 0.0011 0.0045
Onchocerca volvulus 0.0035 0.0037 0.0625
Echinococcus multilocularis transient receptor potential cation channel 0.0036 0.0039 0.0035
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0099 0.0171 0.2522
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0035 0.0038 0.0048
Onchocerca volvulus 0.0095 0.0164 0.2992
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0095 0.0164 0.016
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0037 0.0042 0.0174
Brugia malayi phosphatidylinositol 4-kinase, catalytic, alpha polypeptide 0.0187 0.0357 0.0445
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0095 0.0164 0.0199
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0095 0.0164 0.0199
Schistosoma mansoni receptor protein tyrosine phosphatase n (ia2) 0.0095 0.0164 0.0209
Echinococcus multilocularis transient receptor potential cation channel 0.0036 0.0039 0.0035
Echinococcus granulosus expressed conserved protein 0.0091 0.0155 0.0151
Echinococcus granulosus Niemann Pick C1 protein 0.0138 0.0254 0.025
Trypanosoma brucei DNA polymerase IV, putative 0.0022 0.0011 0.0045
Loa Loa (eye worm) hypothetical protein 0.0095 0.0164 0.0199
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0187 0.0357 0.1735
Onchocerca volvulus 0.0095 0.0164 0.2992
Leishmania major hypothetical protein, conserved 0.1815 0.3776 1
Echinococcus granulosus voltage gated potassium channel 0.0036 0.0039 0.0035
Schistosoma mansoni voltage-gated potassium channel 0.0036 0.0039 0.005
Schistosoma mansoni cpg binding protein 0.0035 0.0037 0.0047
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0036 0.0039 0.0035
Mycobacterium leprae Probable lipase LipE 0.0043 0.0055 0.0306
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0039 0.0045 0.0173
Leishmania major importin beta-1 subunit, putative 0.0051 0.007 0.0186
Echinococcus multilocularis phosphatidylinositol 4,5 bisphosphate 3 kinase 0.0187 0.0357 0.0353
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0095 0.0164 0.016
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0011 0.0045
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0187 0.0357 0.0445
Schistosoma mansoni voltage-gated cation channel 0.0036 0.0039 0.005
Trypanosoma cruzi hypothetical protein, conserved 0.0043 0.0055 0.0142
Onchocerca volvulus 0.0095 0.0164 0.2992
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0187 0.0357 0.0445
Brugia malayi Thioredoxin reductase 0.0099 0.0171 0.0208
Onchocerca volvulus 0.0036 0.0039 0.0664
Echinococcus multilocularis thyroid hormone receptor alpha 0.0021 0.0008 0.0004
Loa Loa (eye worm) hypothetical protein 0.0095 0.0164 0.0199
Schistosoma mansoni calcium-activated potassium channel 0.0036 0.0039 0.005
Brugia malayi acetyltransferase, GNAT family protein 0.0145 0.0268 0.0332
Echinococcus granulosus protein tyrosine phosphatase n9 0.0095 0.0164 0.016
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.025 0.0489 0.7527
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0095 0.0164 0.0199
Onchocerca volvulus Bile acid receptor homolog 0.0021 0.0008 0.0093
Echinococcus granulosus histone lysine methyltransferase setb 0.0054 0.0078 0.0074
Trichomonas vaginalis PIKK family atypical protein kinase 0.0973 0.2007 0.8317
Entamoeba histolytica hypothetical protein 0.0187 0.0357 0.1735
Loa Loa (eye worm) bromodomain containing protein 0.0023 0.0013 0.0006
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0051 0.0169
Echinococcus multilocularis calcium activated potassium channel 0.0036 0.0039 0.0035
Loa Loa (eye worm) hypothetical protein 0.0036 0.0039 0.0039
Trichomonas vaginalis PIKK family atypical protein kinase 0.0973 0.2007 0.8317
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0097 0.0167 0.0783
Echinococcus granulosus inositol monophosphatase 1 0.0039 0.0045 0.0041
Giardia lamblia Protein tyrosine phosphatase 0.0095 0.0164 0.0768
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0095 0.0164 0.016
Trichomonas vaginalis esterase, putative 0.0043 0.0055 0.0186
Echinococcus multilocularis short transient receptor potential channel 6 0.0036 0.0039 0.0035
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0032 0.0031 0.008
Echinococcus granulosus histone acetyltransferase KAT2B 0.0045 0.0057 0.0053
Loa Loa (eye worm) hypothetical protein 0.0095 0.0164 0.0199
Onchocerca volvulus 0.005 0.0069 0.1218
Mycobacterium leprae conserved hypothetical protein 0.0187 0.0357 0.5253
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0187 0.0357 0.0915
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0053 0.0076 0.1881
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0098 0.017 0.0217
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0036 0.0039 0.0039
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0095 0.0164 0.016
Loa Loa (eye worm) hypothetical protein 0.0095 0.0164 0.0199
Schistosoma mansoni hypothetical protein 0.0525 0.1067 0.1359
Echinococcus multilocularis hyperpolarization activated cyclic 0.0036 0.0039 0.0035
Echinococcus granulosus cpg binding protein 0.0039 0.0045 0.0041
Schistosoma mansoni coup transcription factor 0.0021 0.0008 0.001
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.1875 0.3901 1
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0095 0.0164 0.0768
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0036 0.0092
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0095 0.0164 0.016
Echinococcus multilocularis protein dispatched 1 0.0047 0.0063 0.0059
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0095 0.0164 0.0199
Echinococcus multilocularis potassium voltage gated channel protein 0.0036 0.0039 0.0035
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0021 0.0008 0.001
Schistosoma mansoni vesicular amine transporter 0.0036 0.0039 0.005
Loa Loa (eye worm) hypothetical protein 0.0043 0.0055 0.006
Echinococcus granulosus transient receptor potential cation channel 0.0036 0.0039 0.0035
Echinococcus granulosus Protein patched homolog 1 0.0041 0.0051 0.0047
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0043 0.0055 0.0699
Echinococcus multilocularis voltage dependent calcium channel 0.0036 0.0039 0.0035
Onchocerca volvulus 0.0095 0.0164 0.2992
Echinococcus multilocularis PIK kinase, FAT and Armadillo domain containing protein 0.0424 0.0855 0.0851
Toxoplasma gondii transporter, cation channel family protein 0.0036 0.0039 0.0142
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0187 0.0357 0.1735
Giardia lamblia NADH oxidase lateral transfer candidate 0.0034 0.0036 0.0126
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0034 0.0036 0.0032
Mycobacterium tuberculosis Probable reductase 0.0225 0.0437 0.6697
Loa Loa (eye worm) hypothetical protein 0.0095 0.0164 0.0199
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0032 0.0031 0.0103
Trypanosoma cruzi DNA polymerase kappa, putative 0.0022 0.0011 0.0028
Toxoplasma gondii hypothetical protein 0.0059 0.0088 0.0385
Trichomonas vaginalis glucosylceramidase, putative 0.0192 0.0367 0.1485
Trichomonas vaginalis DNA polymerase eta, putative 0.0022 0.0011 0.0001
Leishmania major phosphopantetheinyl transferase-like protein 0.0053 0.0076 0.0201
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0032 0.0031 0.0083
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0187 0.0357 0.0915
Brugia malayi latrophilin 2 splice variant baaae 0.0034 0.0036 0.0036
Echinococcus granulosus transient receptor potential cation channel 0.0036 0.0039 0.0035
Loa Loa (eye worm) hypothetical protein 0.0097 0.0167 0.0202
Brugia malayi Protein-tyrosine phosphatase 0.0095 0.0164 0.0199
Mycobacterium tuberculosis Probable esterase LipL 0.0043 0.0055 0.0699
Trichomonas vaginalis PIKK family atypical protein kinase 0.0549 0.1116 0.4606
Trichomonas vaginalis penicillin-binding protein, putative 0.0043 0.0055 0.0186
Schistosoma mansoni phosphatidylinositol 3-kinase class 0.0187 0.0357 0.0455
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.004 0.0049 0.0044
Giardia lamblia GTOR 0.0973 0.2007 1
Trypanosoma cruzi trypanothione reductase, putative 0.0034 0.0036 0.0092
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0055 0.008 0.0102
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0095 0.0164 0.0199
Loa Loa (eye worm) hypothetical protein 0.0095 0.0164 0.0199
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.005 0.0069 0.0321
Echinococcus granulosus potassium channel KvQLT family member kqt 1 0.0036 0.0039 0.0035
Trichomonas vaginalis glucosylceramidase, putative 0.0293 0.0578 0.2365
Schistosoma mansoni voltage-gated potassium channel 0.0036 0.0039 0.005
Echinococcus granulosus transient receptor potential gamma protein 0.0036 0.0039 0.0035
Entamoeba histolytica phosphatidylinositol 4-kinase, putative 0.0187 0.0357 0.1735
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0025 0.0017 0.0011
Loa Loa (eye worm) hypothetical protein 0.005 0.0069 0.0077
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0055 0.008 0.0102
Loa Loa (eye worm) ryanodine receptor 0.0036 0.0039 0.0039
Brugia malayi CXXC zinc finger family protein 0.0035 0.0037 0.0036
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0973 0.2007 0.2548
Trypanosoma brucei importin beta-1 subunit, putative 0.0062 0.0095 0.0395
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0062 0.0095 0.0244
Trypanosoma cruzi tyrosine specific protein phosphatase, putative 0.0095 0.0164 0.042
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0095 0.0164 0.0199
Loa Loa (eye worm) hypothetical protein 0.0611 0.1248 0.158
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0187 0.0357 0.0455
Loa Loa (eye worm) hypothetical protein 0.0043 0.0055 0.006
Echinococcus multilocularis sodium channel protein 0.0551 0.1122 0.1118
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0095 0.0164 0.0199
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0041 0.0051 0.0055
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.1875 0.3901 0.3898
Mycobacterium ulcerans esterase/lipase LipP 0.0043 0.0055 0.0247
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0021 0.0008 0.0004
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0036 0.0039 0.0142
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0036 0.0039 0.0035
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit 0.0036 0.0039 0.0039
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0187 0.0357 0.1735
Leishmania major GTP-binding protein, putative 0.0022 0.0011 0.0028
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0095 0.0164 0.0199
Echinococcus multilocularis voltage gated potassium channel 0.0036 0.0039 0.0035
Loa Loa (eye worm) hypothetical protein 0.0036 0.0039 0.0039
Onchocerca volvulus 0.0095 0.0164 0.2992
Loa Loa (eye worm) hypothetical protein 0.0095 0.0164 0.0199
Loa Loa (eye worm) hypothetical protein 0.0036 0.0039 0.0039
Plasmodium falciparum phosphatidylinositol 3- and 4-kinase, putative 0.0187 0.0357 1
Schistosoma mansoni non-receptor protein-tyrosine phosphatase 0.0095 0.0164 0.0209
Giardia lamblia Fructose-bisphosphate aldolase 0.0665 0.1361 0.6765
Brugia malayi CHE-14 protein 0.0041 0.0051 0.0055
Echinococcus granulosus voltage dependent calcium channel 0.0036 0.0039 0.0035
Loa Loa (eye worm) hypothetical protein 0.0095 0.0164 0.0199
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0095 0.0164 0.0209
Loa Loa (eye worm) fibronectin type III domain-containing protein 0.0095 0.0164 0.0199
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0973 0.2007 0.5145
Brugia malayi cation channel family protein 0.0036 0.0039 0.0039
Trichomonas vaginalis conserved hypothetical protein 0.0611 0.1248 0.5154
Loa Loa (eye worm) hypothetical protein 0.0051 0.0071 0.008
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0022 0.0011 0.0003
Plasmodium falciparum glutathione reductase 0.0034 0.0036 0.0726
Trichomonas vaginalis PIKK family atypical protein kinase 0.0973 0.2007 0.8317
Trichomonas vaginalis PIKK family atypical protein kinase 0.0741 0.152 0.6289
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0036 0.0039 0.005
Trichomonas vaginalis PIKK family atypical protein kinase 0.0973 0.2007 0.8317
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0173 0.0326 0.1354
Trichomonas vaginalis PIKK family atypical protein kinase 0.0973 0.2007 0.8317
Loa Loa (eye worm) hypothetical protein 0.0037 0.0042 0.0043
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0036 0.0039 0.0035
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0036 0.0039 0.0035
Echinococcus granulosus ecdysone induced protein 78C 0.0021 0.0008 0.0004
Loa Loa (eye worm) beta-lactamase 0.0043 0.0055 0.006
Echinococcus granulosus transient receptor potential cation channel 0.0036 0.0039 0.0035
Plasmodium vivax hypothetical protein, conserved 0.0043 0.0055 0.1289
Echinococcus multilocularis protein tyrosine phosphatase n9 0.0095 0.0164 0.016
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0036 0.0039 0.005
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0045 0.0057 0.0234
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0278 0.0547 0.8439
Trypanosoma cruzi importin beta-1 subunit, putative 0.0051 0.007 0.018
Schistosoma mansoni voltage-gated potassium channel 0.0036 0.0039 0.005
Brugia malayi ImpB/MucB/SamB family protein 0.0022 0.0011 0.0003
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.005 0.0069 0.0321
Mycobacterium ulcerans acyl-CoA synthetase 0.005 0.0069 0.0321
Echinococcus multilocularis receptor type tyrosine protein phosphatase protein tyrosine phosphatase receptor type 0.0095 0.0164 0.016
Echinococcus multilocularis two pore calcium channel protein 1 0.0036 0.0039 0.0035
Loa Loa (eye worm) voltage-dependent calcium channel 0.0036 0.0039 0.0039
Echinococcus multilocularis sterol regulatory element binding protein 0.0041 0.0051 0.0047
Leishmania major 4-coumarate:coa ligase-like protein 0.005 0.0069 0.0182
Loa Loa (eye worm) phosphatidylinositol 3 0.0973 0.2007 0.2548
Loa Loa (eye worm) hypothetical protein 0.0187 0.0357 0.0445
Schistosoma mansoni protein tyrosine phosphatase 0.0095 0.0164 0.0209
Schistosoma mansoni voltage-gated potassium channel KCNQ 0.0036 0.0039 0.005
Echinococcus granulosus potassium voltage gated channel protein 0.0036 0.0039 0.0035
Leishmania major hypothetical protein, conserved 0.0043 0.0055 0.0146
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0095 0.0164 0.0199
Loa Loa (eye worm) hypothetical protein 0.0043 0.0055 0.006
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0022 0.0011 0.0029
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0036 0.0039 0.0035
Echinococcus multilocularis muscleblind protein 0.0469 0.0948 0.0945
Loa Loa (eye worm) hypothetical protein 0.0095 0.0164 0.0199
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit. C. elegans exp-2 ortholog 0.0036 0.0039 0.0039
Brugia malayi FAT domain containing protein 0.0424 0.0855 0.1079
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0043 0.0055 0.0247
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.3757 0.7852 0.7852
Schistosoma mansoni DNA polymerase eta 0.0022 0.0011 0.0014
Trichomonas vaginalis glucosylceramidase, putative 0.0293 0.0578 0.2365
Mycobacterium ulcerans hypothetical protein 0.0192 0.0367 0.1982
Echinococcus granulosus fetal alzheimer antigen falz 0.0027 0.0021 0.0017
Brugia malayi Voltage-gated calcium channel, P/Q-type, alpha subunit. C. elegans unc-2 ortholog 0.0036 0.0039 0.0039
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0039 0.0045 0.0144
Loa Loa (eye worm) hypothetical protein 0.0095 0.0164 0.0199
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0145 0.0268 0.0342
Loa Loa (eye worm) hypothetical protein 0.0036 0.0039 0.0039
Echinococcus granulosus potassium voltage gated channel protein 0.0036 0.0039 0.0035
Onchocerca volvulus 0.0043 0.0055 0.0969
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0032 0.0031 0.008
Loa Loa (eye worm) voltage-gated potassium channel 0.0036 0.0039 0.0039
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0095 0.0164 0.0199
Brugia malayi Bromodomain containing protein 0.0046 0.0061 0.0068
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0055 0.008 0.0091
Loa Loa (eye worm) hypothetical protein 0.0043 0.0055 0.006
Schistosoma mansoni thyroid hormone receptor 0.0021 0.0008 0.001
Echinococcus granulosus expressed protein 0.0033 0.0033 0.0029
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0665 0.1361 0.6765
Brugia malayi hypothetical protein 0.0095 0.0164 0.0199
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0034 0.0036 0.0148
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0034 0.0036 0.0148
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0187 0.0357 0.0455
Giardia lamblia Hypothetical protein 0.0187 0.0357 0.1735
Loa Loa (eye worm) hypothetical protein 0.0095 0.0164 0.0199
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0551 0.1122 0.2971
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0037 0.0042 0.1603
Trichomonas vaginalis PIKK family atypical protein kinase 0.0973 0.2007 0.8317
Schistosoma mansoni voltage-gated potassium channel 0.0036 0.0039 0.005
Trypanosoma cruzi target of rapamycin kinase 3 0.0973 0.2007 0.5145
Schistosoma mansoni bromodomain containing protein 0.0076 0.0124 0.0158
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0034 0.0036 0.0148
Trichomonas vaginalis glucosylceramidase, putative 0.0293 0.0578 0.2365
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0665 0.1361 0.5626
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0011 0.0045
Schistosoma mansoni voltage-gated potassium channel 0.0036 0.0039 0.005
Schistosoma mansoni RAR-like nuclear receptor 0.0021 0.0008 0.001
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.005 0.0069 0.0909
Schistosoma mansoni voltage-dependent calcium channel 0.0036 0.0039 0.005
Echinococcus multilocularis voltage gated hydrogen channel 1 0.0036 0.0039 0.0035
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0045 0.0057 0.1351
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0095 0.0164 0.0199
Toxoplasma gondii hypothetical protein 0.0036 0.0039 0.0142
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0051 0.0072 0.0297
Trichomonas vaginalis PIKK family atypical protein kinase 0.0973 0.2007 0.8317
Schistosoma mansoni retinoic acid receptor RXR 0.0021 0.0008 0.001
Trypanosoma cruzi DNA polymerase kappa, putative 0.0022 0.0011 0.0028
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0035 0.0038 0.0426
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0011 0.0045
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0037 0.0042 0.0493
Trichomonas vaginalis rotamase, putative 0.0032 0.0031 0.0086
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.005 0.007 0.0078
Toxoplasma gondii thioredoxin reductase 0.0099 0.0171 0.0804
Trichomonas vaginalis glucosylceramidase, putative 0.0192 0.0367 0.1485
Onchocerca volvulus 0.0095 0.0164 0.2992
Loa Loa (eye worm) voltage-gated calcium channel 0.0036 0.0039 0.0039
Echinococcus granulosus importin subunit beta 1 0.0062 0.0095 0.0091
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0043 0.0055 0.007
Toxoplasma gondii ABC1 family protein 0.0043 0.0055 0.0224
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0095 0.0164 0.0199
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0036 0.0039 0.0142
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0021 0.0008 0.0004
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0053 0.0076 0.0361
Treponema pallidum fructose-bisphosphate aldolase 0.0665 0.1361 1
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.045 0.0908 0.2329
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0036 0.0039 0.0035
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0187 0.0357 0.0445
Loa Loa (eye worm) hypothetical protein 0.005 0.0069 0.0077
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0053 0.0076 0.0302
Loa Loa (eye worm) phosphatidylinositol 3 0.1165 0.2411 0.3063
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0051 0.0072 0.0184
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0034 0.0036 0.0126
Echinococcus granulosus calcium activated potassium channel 0.0036 0.0039 0.0035
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0045 0.0057 0.0195
Loa Loa (eye worm) hypothetical protein 0.0037 0.0042 0.0043
Schistosoma mansoni voltage-gated potassium channel 0.0036 0.0039 0.005
Onchocerca volvulus 0.0095 0.0164 0.2992
Trichomonas vaginalis PIKK family atypical protein kinase 0.0549 0.1116 0.4606
Trichomonas vaginalis glucosylceramidase, putative 0.0293 0.0578 0.2365
Loa Loa (eye worm) hypothetical protein 0.0037 0.0042 0.0043
Echinococcus multilocularis potassium voltage gated channel subfamily A 0.0036 0.0039 0.0035
Schistosoma mansoni hypothetical protein 0.0034 0.0036 0.0046
Echinococcus multilocularis potassium voltage gated channel subfamily KQT 0.0036 0.0039 0.0035
Schistosoma mansoni voltage-gated ion channel 0.0036 0.0039 0.005
Echinococcus multilocularis short transient receptor potential channel 6 0.0036 0.0039 0.0035
Leishmania major phosphatidylinositol kinase, putative 0.0187 0.0357 0.0946
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0187 0.0357 0.1735
Echinococcus granulosus snurportin 1 0.0667 0.1365 0.1361
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0095 0.0164 0.0199
Leishmania major tyrosine specific protein phosphatase, putative 0.0095 0.0164 0.0434
Toxoplasma gondii transporter, cation channel family protein 0.0036 0.0039 0.0142
Loa Loa (eye worm) hypothetical protein 0.0036 0.0039 0.0039
Schistosoma mansoni inositol monophosphatase 0.0039 0.0045 0.0058
Echinococcus multilocularis hypothetical protein 0.0095 0.0164 0.016
Echinococcus granulosus transient receptor potential cation channel 0.0036 0.0039 0.0035
Loa Loa (eye worm) hypothetical protein 0.0043 0.0055 0.006
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0325 0.0646 1
Loa Loa (eye worm) thioredoxin reductase 0.0099 0.0171 0.0208
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0033 0.0033 0.0031
Echinococcus granulosus GTP binding nuclear protein Ran 0.0022 0.0011 0.0007
Trichomonas vaginalis glucosylceramidase, putative 0.0192 0.0367 0.1485
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.005 0.0069 0.0525
Echinococcus granulosus L aminoadipate semialdehyde 0.0189 0.0361 0.0357
Onchocerca volvulus 0.0189 0.0361 0.6665
Entamoeba histolytica hypothetical protein 0.0051 0.007 0.0299
Brugia malayi Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit 0.0036 0.0039 0.0039
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0225 0.0437 0.6697
Mycobacterium tuberculosis Probable lipase LipE 0.0043 0.0055 0.0699
Trichomonas vaginalis PIKK family atypical protein kinase 0.0362 0.0723 0.2968
Onchocerca volvulus 0.0095 0.0164 0.2992
Trichomonas vaginalis importin beta-1, putative 0.0051 0.007 0.0249
Brugia malayi Protein-tyrosine phosphatase containing protein 0.3757 0.7852 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0036 0.0092
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0034 0.0036 0.0095
Echinococcus granulosus phosphatidylinositol 4 kinase alpha 0.0187 0.0357 0.0353
Echinococcus multilocularis phosphatidylinositol 4 phosphate 3 kinase C2 0.0187 0.0357 0.0353
Trypanosoma cruzi DNA polymerase kappa, putative 0.0022 0.0011 0.0028
Echinococcus multilocularis 0.0187 0.0357 0.0353
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0036 0.0039 0.005
Onchocerca volvulus 0.0187 0.0357 0.6583
Loa Loa (eye worm) hypothetical protein 0.0095 0.0164 0.0199
Schistosoma mansoni phosphatidylinositol 4-kinase type-II 0.0187 0.0357 0.0455
Echinococcus granulosus Potassium voltage gated channel protein Shaw 0.0036 0.0039 0.0035
Schistosoma mansoni transient receptor potential channel 0.0036 0.0039 0.005
Onchocerca volvulus 0.0095 0.0164 0.2992
Echinococcus granulosus voltage gated potassium channel 0.0036 0.0039 0.0035
Brugia malayi Pre-SET motif family protein 0.0241 0.0471 0.059
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0187 0.0357 0.1443
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0008 0.0004
Onchocerca volvulus 0.0095 0.0164 0.2992
Trichomonas vaginalis PIKK family atypical protein kinase 0.0973 0.2007 0.8317
Trypanosoma cruzi DNA polymerase kappa, putative 0.0022 0.0011 0.0028
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0095 0.0164 0.016
Mycobacterium ulcerans hypothetical protein 0.0043 0.0055 0.0247
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0021 0.0008 0.0004
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0036 0.0039 0.005
Brugia malayi Calcitonin receptor-like protein seb-1 0.005 0.007 0.0078
Echinococcus granulosus sodium leak channel non selective protein 0.0036 0.0039 0.0035
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0187 0.0357 0.1443
Brugia malayi ImpB/MucB/SamB family protein 0.0022 0.0011 0.0003
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0036 0.0039 0.0039
Brugia malayi Cyclic-nucleotide gated cation channel 0.0036 0.0039 0.0039
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0036 0.0039 0.0035
Leishmania major DNA polymerase kappa, putative 0.0022 0.0011 0.0029
Trichomonas vaginalis pten, drome, putative 0.0095 0.0164 0.0639
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0036 0.0039 0.0035
Echinococcus multilocularis zinc finger protein 0.0027 0.0022 0.0017
Trichomonas vaginalis glutathione reductase, putative 0.0034 0.0036 0.0105
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.005 0.0069 0.0321
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0187 0.0357 0.1443
Brugia malayi hypothetical protein 0.0035 0.0038 0.0038
Schistosoma mansoni patched 1 0.0041 0.0051 0.0065
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0811 0.1667 0.2115
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0033 0.0034 0.003
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.025 0.0489 0.7422
Echinococcus multilocularis geminin 0.0525 0.1067 0.1063
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0095 0.0164 0.0199
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0036 0.0039 0.0664
Trichomonas vaginalis PIKK family atypical protein kinase 0.0187 0.0357 0.1443
Trichomonas vaginalis PIKK family atypical protein kinase 0.0973 0.2007 0.8317
Schistosoma mansoni rotamase 0.0033 0.0033 0.0042
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0667 0.1365 0.1729
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0045 0.0116
Echinococcus multilocularis sodium leak channel non selective protein 0.0036 0.0039 0.0035
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0187 0.0357 0.1443
Echinococcus granulosus two pore calcium channel protein 2 0.0036 0.0039 0.0035
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0022 0.0011 0.0001
Trichomonas vaginalis PIKK family atypical protein kinase 0.0187 0.0357 0.1443
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0075 0.0121 0.0154
Loa Loa (eye worm) hypothetical protein 0.0043 0.0055 0.006
Brugia malayi Dual specificity protein phosphatase CDC14B 0.0095 0.0164 0.0199
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0036 0.0039 0.0035
Plasmodium falciparum thioredoxin reductase 0.0034 0.0036 0.0726
Loa Loa (eye worm) hypothetical protein 0.0095 0.0164 0.0199
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0187 0.0357 0.1443
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0095 0.0164 0.0199
Echinococcus granulosus dna polymerase kappa 0.0022 0.0011 0.0007
Plasmodium vivax importin-beta 2, putative 0.0062 0.0095 0.2441
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0095 0.0164 0.016
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0045 0.0116
Echinococcus granulosus geminin 0.0525 0.1067 0.1063
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0036 0.0039 0.0035
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0051 0.007 0.0249
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0051 0.007 0.0249
Onchocerca volvulus 0.0095 0.0164 0.2992
Trichomonas vaginalis PIKK family atypical protein kinase 0.0973 0.2007 0.8317
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0036 0.0039 0.0039
Trichomonas vaginalis PIKK family atypical protein kinase 0.0973 0.2007 0.8317
Trichomonas vaginalis PIKK family atypical protein kinase 0.0549 0.1116 0.4606
Toxoplasma gondii HEAT repeat-containing protein 0.0062 0.0095 0.0424
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0045 0.0057 0.0234
Brugia malayi Voltage-gated potassium channel, KCNQ (Kv7-like) alpha-subunit. C. elegans kqt-1 ortholog 0.0036 0.0039 0.0039
Trichomonas vaginalis glucosylceramidase, putative 0.0192 0.0367 0.1485
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0293 0.0578 0.0727
Leishmania major phosphatidylinositol 3-kinase, putative 0.0973 0.2007 0.5315
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0095 0.0164 0.016
Loa Loa (eye worm) hypothetical protein 0.0036 0.0039 0.0039
Plasmodium falciparum thioredoxin reductase 0.0099 0.0171 0.4634
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0034 0.0036 0.0726
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0039 0.0045 0.0144
Entamoeba histolytica deoxycytidyl transferase, putative 0.0022 0.0011 0.0001
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0045 0.0187
Schistosoma mansoni hypothetical protein 0.0036 0.0039 0.005
Schistosoma mansoni voltage-gated potassium channel 0.0036 0.0039 0.005
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0973 0.2007 0.2004
Onchocerca volvulus 0.0095 0.0164 0.2992
Entamoeba histolytica acyl-CoA synthetase, putative 0.005 0.0069 0.0291
Schistosoma mansoni voltage-gated potassium channel 0.0036 0.0039 0.005
Brugia malayi glutaminase DH11.1 0.0879 0.181 0.2297
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0145 0.0268 0.0264
Loa Loa (eye worm) glutaminase 0.0879 0.181 0.2297
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0034 0.0036 0.0092
Trichomonas vaginalis glucosylceramidase, putative 0.0192 0.0367 0.1485
Echinococcus granulosus sodium channel protein 0.0551 0.1122 0.1118
Loa Loa (eye worm) hypothetical protein 0.0079 0.013 0.0156
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.1875 0.3901 0.4967
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit. C. elegans egl-36 ortholog 0.0036 0.0039 0.0039
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0036 0.0092
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0095 0.0164 0.0199
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0035 0.0037 0.0406
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0036 0.0039 0.0035
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0973 0.2007 0.2004
Leishmania major phosphatidylinositol 4-kinase, putative 0.0187 0.0357 0.0946
Brugia malayi AMP-binding enzyme family protein 0.005 0.0069 0.0077
Echinococcus granulosus phosphatidylinositol 4 phosphate 3 kinase C2 0.0187 0.0357 0.0353
Trichomonas vaginalis PIKK family atypical protein kinase 0.0549 0.1116 0.4606
Trichomonas vaginalis PIKK family atypical protein kinase 0.0549 0.1116 0.4606
Echinococcus multilocularis snurportin 1 0.0667 0.1365 0.1361
Echinococcus granulosus PIK kinase FAT and Armadillo domain containing protein 0.0424 0.0855 0.0851
Plasmodium vivax thioredoxin reductase, putative 0.0099 0.0171 0.4634
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0043 0.0055 0.007
Schistosoma mansoni ryanodine receptor related 0.0036 0.0039 0.005
Echinococcus multilocularis Niemann Pick C1 protein 0.0138 0.0254 0.025
Echinococcus multilocularis 0.0095 0.0164 0.016
Plasmodium vivax SET domain protein, putative 0.0035 0.0038 0.0792
Loa Loa (eye worm) acetyltransferase 0.0145 0.0268 0.0332
Mycobacterium tuberculosis Conserved hypothetical protein 0.0192 0.0367 0.5609
Schistosoma mansoni inositol 145-trisphosphate receptor 0.0036 0.0039 0.005
Loa Loa (eye worm) hypothetical protein 0.0192 0.0368 0.0459
Echinococcus multilocularis potassium voltage gated channel protein 0.0036 0.0039 0.0035
Entamoeba histolytica acyl-coA synthetase, putative 0.005 0.0069 0.0291
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0095 0.0164 0.0199
Entamoeba histolytica acetyltransferase, GNAT family 0.0038 0.0045 0.017
Echinococcus multilocularis voltage dependent calcium channel 0.0036 0.0039 0.0035
Schistosoma mansoni receptor protein tyrosine phosphatase n (ia2) 0.0095 0.0164 0.0209
Brugia malayi protein-tyrosine phosphatase Lar-like precursor, putative 0.0095 0.0164 0.0199
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0665 0.1361 0.5626
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0095 0.0164 0.016
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0173 0.0326 0.0865
Brugia malayi beta-lactamase family protein 0.0043 0.0055 0.006
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.005 0.0069 0.0909
Mycobacterium leprae conserved hypothetical protein 0.0043 0.0055 0.0306
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0187 0.0357 0.1735
Trypanosoma brucei inositol 1,4,5-trisphosphate receptor 0.0036 0.0039 0.0161
Brugia malayi Large-conductance calcium-activated potassium channel Slo-1 (KCNMA) alpha subunit. C. elegans slo-1 ortholog 0.0036 0.0039 0.0039
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.025 0.0489 0.7527
Mycobacterium tuberculosis Probable hydrolase 0.0043 0.0055 0.0699
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0095 0.0164 0.016
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0055 0.008 0.0076

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) = 0.2239 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of DNA Polymerase Beta. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 0.7079 um PUBCHEM_BIOASSAY: qHTS Inhibitors of AmpC Beta-Lactamase (assay with detergent). (Class of assay: confirmatory) [Related pubchem assays: 1002 (Confirmation Concentration-Response Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent)), 585 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay without detergent) - a screen old NIH MLSMR collection), 584 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay with detergent) - a screen of the old NIH MLSMR collection), 1003 (Confirmation Cuvette-Based Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent))] ChEMBL. No reference
Potency (functional) 2.8184 uM PubChem BioAssay. qHTS for Agonist of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 79.4328 uM PUBCHEM_BIOASSAY: HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488962] ChEMBL. No reference
Potency (functional) 150.0297 uM PubChem BioAssay. qHTS Assay for Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1). (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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