TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 512.669 | Formula: C24H40N2O8Si
H donors: 2 H acceptors: 4 LogP: 2.12 Rotable bonds: 9
Rule of 5 violations (Lipinski): 2
SMILES: O=C(CC1(C)OCC(C1)(C)O)OC[C@@H]1O[C@@H](C[C@@H]1O[Si](C(C)(C)C)(C)C)n1cc(C)c(=O)[nH]c1=O
InChi: 1S/C24H40N2O8Si/c1-15-11-26(21(29)25-20(15)28)18-9-16(34-35(7,8)22(2,3)4)17(33-18)12-31-19(27)10-24(6)13-23(5,30)14-32-24/h11,16-18,30H,9-10,12-14H2,1-8H3,(H,25,28,29)/t16-,17+,18+,23?,24?/m0/s1
InChiKey: AVKKTQOCAFFDJX-KJYPIDOJSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Schistosoma mansoni	voltage-gated potassium channel	0.0045	0.0046	0.0046
Echinococcus granulosus	lamin dm0	0.0028	0.0009	0.0011
Trichomonas vaginalis	protein transport protein sec7, putative	0.0068	0.0097	0.0426
Trichomonas vaginalis	TKL family protein kinase	0.0056	0.007	0.0251
Schistosoma mansoni	centaurin alpha	0.0068	0.0097	0.0097
Trichomonas vaginalis	centaurin beta, putative	0.0068	0.0097	0.0426
Trichomonas vaginalis	guanyl-nucleotide exchange factor, putative	0.0068	0.0097	0.0426
Plasmodium vivax	PH domain containing protein	0.0068	0.0097	0.6027
Echinococcus multilocularis	musashi	0.0028	0.0009	0.0011
Loa Loa (eye worm)	hypothetical protein	0.0745	0.1578	0.1578
Loa Loa (eye worm)	AGC/GRK/BARK protein kinase	0.3524	0.7653	0.7653
Echinococcus granulosus	collagen type iv alpha 3 binding protein	0.0068	0.0097	0.0116
Echinococcus granulosus	tyrosine protein kinase pr2	0.0056	0.007	0.0084
Brugia malayi	Adenylate and Guanylate cyclase catalytic domain containing protein	0.0056	0.007	0.007
Leishmania major	protein kinase, putative	0.0087	0.0138	1
Brugia malayi	Probable G protein-coupled receptor kinase F19C6.1, putative	0.3852	0.837	0.837
Schistosoma mansoni	regulator of G protein signaling	0.0745	0.1578	0.1578
Trichomonas vaginalis	conserved hypothetical protein	0.0745	0.1578	1
Brugia malayi	Corticotropin releasing factor receptor 2 precursor, putative	0.0049	0.0056	0.0056
Trichomonas vaginalis	TKL family protein kinase	0.0056	0.007	0.0251
Trypanosoma brucei	aurora B kinase	0.0078	0.0119	0.8157
Echinococcus granulosus	regulator of G protein signaling 7	0.0745	0.1578	0.1885
Trypanosoma brucei	protein kinase, putative	0.0087	0.0138	1
Trichomonas vaginalis	AGC family protein kinase	0.0078	0.0119	0.0565
Schistosoma mansoni	family S12 unassigned peptidase (S12 family)	0.004	0.0036	0.0036
Trypanosoma cruzi	Serine/threonine-protein kinase NEK17, putative	0.0087	0.0138	1
Brugia malayi	PH domain containing protein	0.0068	0.0097	0.0097
Schistosoma mansoni	protein kinase	0.0074	0.0111	0.0111
Trichomonas vaginalis	TKL family protein kinase	0.0056	0.007	0.0251
Brugia malayi	Protein kinase domain containing protein	0.0056	0.007	0.007
Schistosoma mansoni	hypothetical protein	0.0068	0.0097	0.0097
Echinococcus granulosus	pdz domain containing protein	0.0068	0.0097	0.0116
Echinococcus multilocularis	tyrosine protein kinase Fps85D	0.0056	0.007	0.0084
Echinococcus multilocularis	type II inositol 3,4 bisphosphate 4 phosphatase	0.0068	0.0097	0.0116
Trichomonas vaginalis	TKL family protein kinase	0.0056	0.007	0.0251
Trichomonas vaginalis	conserved hypothetical protein	0.0068	0.0097	0.0426
Schistosoma mansoni	tyrosine kinase	0.0056	0.007	0.007
Echinococcus multilocularis	roundabout 2	0.0116	0.0201	0.024
Trichomonas vaginalis	regulator of G protein signaling 5, rgs5, putative	0.0745	0.1578	1
Trichomonas vaginalis	AGC family protein kinase	0.0056	0.007	0.0251
Trichomonas vaginalis	conserved hypothetical protein	0.0068	0.0097	0.0426
Schistosoma mansoni	tar DNA-binding protein	0.0063	0.0085	0.0085
Mycobacterium tuberculosis	NADPH-dependent mycothiol reductase Mtr	0.0049	0.0055	0.0397
Echinococcus multilocularis	aurora kinase A	0.0078	0.0119	0.0142
Trichomonas vaginalis	TKL family protein kinase	0.0056	0.007	0.0251
Trichomonas vaginalis	conserved hypothetical protein	0.0068	0.0097	0.0426
Loa Loa (eye worm)	hypothetical protein	0.0371	0.0759	0.0759
Schistosoma mansoni	tyrosine kinase	0.0056	0.007	0.007
Brugia malayi	C-terminal src kinase protein 1	0.0056	0.007	0.007
Loa Loa (eye worm)	TKL/RAF/KSR protein kinase	0.0056	0.007	0.007
Brugia malayi	Syntrophin-1	0.0068	0.0097	0.0097
Echinococcus granulosus	mitogen-activated protein kinase kinase kinase 9	0.0056	0.007	0.0084
Entamoeba histolytica	hypothetical protein	0.0745	0.1578	1
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.01	0.0167	0.0167
Loa Loa (eye worm)	thioredoxin reductase	0.0049	0.0055	0.0055
Brugia malayi	Probable tyrosine-protein kinase kin-31	0.0056	0.007	0.007
Schistosoma mansoni	protein kinase	0.0056	0.007	0.007
Onchocerca volvulus		0.0056	0.007	0.033
Echinococcus multilocularis	G protein coupled receptor kinase 6	0.3852	0.837	1
Echinococcus multilocularis	DCC interacting protein 13 beta	0.0068	0.0097	0.0116
Entamoeba histolytica	protein kinase domain containing protein	0.0074	0.0111	0.0267
Schistosoma mansoni	serine/threonine-protein kinase	0.0087	0.0138	0.0138
Echinococcus multilocularis	beta 1 syntrophin	0.0068	0.0097	0.0116
Loa Loa (eye worm)	TK protein kinase	0.0056	0.007	0.007
Echinococcus multilocularis	Oxysterol binding protein 11	0.0068	0.0097	0.0116
Trichomonas vaginalis	TKL family protein kinase	0.0056	0.007	0.0251
Echinococcus multilocularis	tyrosine protein kinase shark	0.0056	0.007	0.0084
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0056	0.007	0.0084
Trichomonas vaginalis	TKL family protein kinase	0.0056	0.007	0.0251
Echinococcus granulosus	aurora kinase A	0.0078	0.0119	0.0142
Loa Loa (eye worm)	cytohesin 3	0.0068	0.0097	0.0097
Trichomonas vaginalis	STE family protein kinase	0.0056	0.007	0.0251
Entamoeba histolytica	hypothetical protein, conserved domain containing	0.0068	0.0097	0.0179
Loa Loa (eye worm)	rho-GTPase-activating	0.0068	0.0097	0.0097
Brugia malayi	PH domain containing protein	0.0068	0.0097	0.0097
Echinococcus multilocularis	tyrosine kinase	0.0056	0.007	0.0084
Schistosoma mansoni	protein kinase	0.0056	0.007	0.007
Echinococcus multilocularis	dual specificity testis specific protein kinase	0.0074	0.0111	0.0132
Schistosoma mansoni	zinc finger protein	0.0068	0.0097	0.0097
Loa Loa (eye worm)	hypothetical protein	0.004	0.0036	0.0036
Echinococcus multilocularis	epidermal growth factor receptor	0.0056	0.007	0.0084
Trichomonas vaginalis	TKL family protein kinase	0.0056	0.007	0.0251
Echinococcus granulosus	defective proboscis extension response	0.0111	0.019	0.0227
Loa Loa (eye worm)	sema domain-containing protein	0.0371	0.0759	0.0759
Entamoeba histolytica	hypothetical protein	0.0068	0.0097	0.0179
Trypanosoma brucei	Serine/threonine-protein kinase NEK21, putative	0.0087	0.0138	1
Loa Loa (eye worm)	hypothetical protein	0.0068	0.0097	0.0097
Echinococcus multilocularis	pleckstrin y domain containing family A	0.0068	0.0097	0.0116
Brugia malayi	Oxysterol binding protein	0.0068	0.0097	0.0097
Trichomonas vaginalis	conserved hypothetical protein	0.0068	0.0097	0.0426
Trichomonas vaginalis	conserved hypothetical protein	0.0056	0.007	0.0251
Mycobacterium leprae	PROBABLE NADH DEHYDROGENASE NDH	0.0112	0.0193	0.8513
Echinococcus granulosus	beta LACTamase domain containing family member	0.004	0.0036	0.0043
Brugia malayi	beta-lactamase family protein	0.004	0.0036	0.0036
Entamoeba histolytica	PH domain containing protein kinase, putative	0.0087	0.0138	0.0446
Leishmania major	hypothetical protein, conserved	0.0068	0.0097	0.7075
Trypanosoma cruzi	Protein kinase B	0.0087	0.0138	1
Entamoeba histolytica	protein kinase, putative	0.0087	0.0138	0.0446
Echinococcus granulosus	raf serine:threonine protein kinase	0.0056	0.007	0.0084
Schistosoma mansoni	hypothetical protein	0.0371	0.0759	0.0759
Loa Loa (eye worm)	RGS-3 protein	0.0745	0.1578	0.1578
Trichomonas vaginalis	conserved hypothetical protein	0.0068	0.0097	0.0426
Loa Loa (eye worm)	hypothetical protein	0.0162	0.0303	0.0303
Brugia malayi	hypothetical protein	0.0056	0.007	0.007
Echinococcus granulosus	receptor type guanylyl cyclase	0.0056	0.007	0.0084
Loa Loa (eye worm)	TKL/MLK/HH498 protein kinase	0.0056	0.007	0.007
Trichomonas vaginalis	conserved hypothetical protein	0.0068	0.0097	0.0426
Entamoeba histolytica	protein kinase, putative	0.0087	0.0138	0.0446
Schistosoma mansoni	hypothetical protein	0.0029	0.0011	0.0011
Echinococcus granulosus	neurotracting:lsamp:neurotrimin:obcam	0.0111	0.019	0.0227
Loa Loa (eye worm)	TK/FER protein kinase	0.0056	0.007	0.007
Loa Loa (eye worm)	hypothetical protein	0.0068	0.0097	0.0097
Loa Loa (eye worm)	oxysterol binding protein	0.0068	0.0097	0.0097
Onchocerca volvulus		0.0056	0.007	0.033
Trichomonas vaginalis	conserved hypothetical protein	0.0162	0.0303	0.1756
Loa Loa (eye worm)	TK protein kinase	0.0056	0.007	0.007
Entamoeba histolytica	PH domain containing protein	0.0068	0.0097	0.0179
Trichomonas vaginalis	TKL family protein kinase	0.0056	0.007	0.0251
Schistosoma mansoni	tyrosine-protein kinase fps85d	0.0056	0.007	0.007
Echinococcus granulosus	epidermal growth factor receptor	0.0056	0.007	0.0084
Schistosoma mansoni	regulator of G protein signaling	0.0745	0.1578	0.1578
Loa Loa (eye worm)	hypothetical protein	0.0503	0.1048	0.1048
Trypanosoma cruzi	NEK family Serine/threonine-protein kinase, putative	0.0068	0.0097	0.6027
Echinococcus multilocularis	semaphorin 5B	0.0371	0.0759	0.0906
Onchocerca volvulus		0.004	0.0036	0.0146
Schistosoma mansoni	protein kinase	0.0074	0.0111	0.0111
Brugia malayi	bone morphogenetic protein type 1 receptor	0.0056	0.007	0.007
Trichomonas vaginalis	conserved hypothetical protein	0.0068	0.0097	0.0426
Entamoeba histolytica	hypothetical protein	0.0087	0.0138	0.0446
Trichomonas vaginalis	AGC family protein kinase	0.0087	0.0138	0.0686
Trichomonas vaginalis	hypothetical protein	0.0068	0.0097	0.0426
Trichomonas vaginalis	conserved hypothetical protein	0.0162	0.0303	0.1756
Trichomonas vaginalis	ribosomal protein S6 kinase, 90kD, polypeptide, putative	0.0087	0.0138	0.0686
Trichomonas vaginalis	Clan MA, family M8, leishmanolysin-like metallopeptidase	0.0162	0.0303	0.1756
Echinococcus granulosus	activated cdc42 kinase 1	0.0056	0.007	0.0084
Echinococcus granulosus	tyrosine protein kinase csk	0.0056	0.007	0.0084
Schistosoma mansoni	phosphoinositol 4-phosphate adaptor protein	0.0068	0.0097	0.0097
Loa Loa (eye worm)	TK/FER protein kinase	0.0056	0.007	0.007
Echinococcus granulosus	transcription factor collier	0.0162	0.0303	0.0362
Echinococcus granulosus	A kinase anchor protein 10 mitochondrial	0.0745	0.1578	0.1885
Trypanosoma brucei	Pseudokinase, putative	0.0056	0.007	0.3363
Schistosoma mansoni	cell adhesion molecule	0.0116	0.0201	0.0201
Trypanosoma cruzi	NIMA-related kinase, putative	0.0087	0.0138	1
Trichomonas vaginalis	TKL family protein kinase	0.0056	0.007	0.0251
Brugia malayi	regulator of G-protein signaling egl-10	0.0745	0.1578	0.1578
Plasmodium vivax	glutathione reductase, putative	0.0049	0.0055	0.1868
Trypanosoma cruzi	protein kinase, putative	0.0056	0.007	0.3363
Mycobacterium tuberculosis	Probable membrane NADH dehydrogenase NdhA	0.0112	0.0193	0.3284
Echinococcus multilocularis	Pleckstrin y	0.0068	0.0097	0.0116
Schistosoma mansoni	serine/threonine protein kinase	0.0078	0.0119	0.0119
Echinococcus granulosus	arf GAP with SH3 domain ANK repeat and PH	0.0068	0.0097	0.0116
Onchocerca volvulus		0.0056	0.007	0.033
Trichomonas vaginalis	TKL family protein kinase	0.0056	0.007	0.0251
Schistosoma mansoni	tyrosine kinase	0.0056	0.007	0.007
Schistosoma mansoni	tyrosine kinase	0.0056	0.007	0.007
Echinococcus granulosus	DCC interacting protein 13 beta	0.0068	0.0097	0.0116
Loa Loa (eye worm)	hypothetical protein	0.0371	0.0759	0.0759
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	0.01	0.0167	0.02
Loa Loa (eye worm)	TK/ACK protein kinase	0.0056	0.007	0.007
Brugia malayi	Protein kinase domain containing protein	0.0056	0.007	0.007
Echinococcus granulosus	beta 1 syntrophin	0.0068	0.0097	0.0116
Toxoplasma gondii	calcium dependent protein kinase CDPK8	0.0074	0.0111	0.8039
Echinococcus granulosus	tyrosine protein kinase transmembrane receptor	0.0056	0.007	0.0084
Brugia malayi	Furin-like cysteine rich region family protein	0.0056	0.007	0.007
Schistosoma mansoni	serine/threonine RGC	0.0056	0.007	0.007
Trichomonas vaginalis	br serine/threonine-protein kinase, putative	0.0056	0.007	0.0251
Trichomonas vaginalis	conserved hypothetical protein	0.0056	0.007	0.0251
Brugia malayi	SH2 domain containing protein	0.0056	0.007	0.007
Plasmodium falciparum	tyrosine kinase-like protein	0.0056	0.007	0.5114
Loa Loa (eye worm)	AUR protein kinase	0.0078	0.0119	0.0119
Plasmodium falciparum	conserved Plasmodium protein, unknown function	0.0068	0.0097	0.7075
Echinococcus granulosus	Pleckstrin domain containing protein family B	0.0068	0.0097	0.0116
Brugia malayi	Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog	0.0041	0.0038	0.0038
Onchocerca volvulus	Abnormal cell migration protein 10 homolog	0.0068	0.0097	0.0476
Trypanosoma cruzi	hypothetical protein	0.0068	0.0097	0.6027
Echinococcus granulosus	neuroglian	0.0111	0.019	0.0227
Trichomonas vaginalis	AGC family protein kinase	0.0087	0.0138	0.0686
Schistosoma mansoni	tyrosine kinase	0.0056	0.007	0.007
Echinococcus granulosus	oxysterol binding protein 1	0.0068	0.0097	0.0116
Trypanosoma brucei	AGC/RSK family serine/threonine kinase, putative	0.0056	0.007	0.3363
Echinococcus granulosus	Rho GTPase activating protein 24	0.0068	0.0097	0.0116
Trichomonas vaginalis	conserved hypothetical protein	0.0068	0.0097	0.0426
Plasmodium falciparum	calcium-dependent protein kinase 7	0.0087	0.0138	1
Echinococcus granulosus	GRB2 associated binding protein 3	0.0068	0.0097	0.0116
Echinococcus multilocularis	activin receptor type	0.0074	0.0111	0.0132
Entamoeba histolytica	protein kinase, putative	0.0087	0.0138	0.0446
Echinococcus granulosus	tyrosine protein kinase Fyn	0.0056	0.007	0.0084
Trichomonas vaginalis	AGC family protein kinase	0.0087	0.0138	0.0686
Echinococcus multilocularis	tyrosine protein kinase transmembrane receptor	0.0056	0.007	0.0084
Echinococcus multilocularis	macrophage colony stimulating factor 1 receptor	0.0056	0.007	0.0084
Brugia malayi	Dynamin	0.0068	0.0097	0.0097
Echinococcus multilocularis	protein kinase	0.0056	0.007	0.0084
Schistosoma mansoni	serine/threonine protein kinase	0.0056	0.007	0.007
Trichomonas vaginalis	TKL family protein kinase	0.0056	0.007	0.0251
Trichomonas vaginalis	TKL family protein kinase	0.0056	0.007	0.0251
Trichomonas vaginalis	TKL family protein kinase	0.0056	0.007	0.0251
Echinococcus granulosus	activin receptor type	0.0074	0.0111	0.0132
Trichomonas vaginalis	conserved hypothetical protein	0.0068	0.0097	0.0426
Entamoeba histolytica	protein kinase, putative	0.0087	0.0138	0.0446
Echinococcus multilocularis	tyrosine protein kinase Btk29A	0.0056	0.007	0.0084
Echinococcus multilocularis	geminin	0.0534	0.1115	0.1332
Entamoeba histolytica	protein kinase domain containing protein	0.0078	0.0119	0.0322
Schistosoma mansoni	rhogef and pleckstrin domain protein	0.0068	0.0097	0.0097
Loa Loa (eye worm)	hypothetical protein	0.0371	0.0759	0.0759
Schistosoma mansoni	tar DNA-binding protein	0.0063	0.0085	0.0085
Brugia malayi	Probable exocyst complex component Sec5	0.0162	0.0303	0.0303
Plasmodium vivax	calcium-dependent protein kinase 7, putative	0.0087	0.0138	1
Onchocerca volvulus		0.0056	0.007	0.033
Trichomonas vaginalis	TKL family protein kinase	0.0056	0.007	0.0251
Onchocerca volvulus		0.0056	0.007	0.033
Trichomonas vaginalis	ankyrin repeat-containing protein, putative	0.0068	0.0097	0.0426
Echinococcus granulosus	3'partial\|retinal guanylyl cyclase 2	0.0056	0.007	0.0084
Entamoeba histolytica	hypothetical protein	0.0162	0.0303	0.1544
Schistosoma mansoni	regulator of G protein signaling 17 19 20 (rgs17 19 20)	0.0745	0.1578	0.1578
Echinococcus multilocularis	regulator of G protein signaling	0.0745	0.1578	0.1885
Trichomonas vaginalis	TKL family protein kinase	0.0056	0.007	0.0251
Entamoeba histolytica	hypothetical protein, conserved domain containing	0.0068	0.0097	0.0179
Brugia malayi	hypothetical protein	0.0158	0.0292	0.0292
Echinococcus multilocularis	tyrosine protein kinase Blk	0.0056	0.007	0.0084
Brugia malayi	TBC domain containing protein	0.0068	0.0097	0.0097
Loa Loa (eye worm)	PXA domain-containing protein	0.0745	0.1578	0.1578
Loa Loa (eye worm)	TK/FER protein kinase	0.0056	0.007	0.007
Brugia malayi	Protein kinase domain containing protein	0.0056	0.007	0.007
Loa Loa (eye worm)	TK protein kinase	0.0056	0.007	0.007
Entamoeba histolytica	hypothetical protein	0.0068	0.0097	0.0179
Plasmodium vivax	tyrosine kinase-like protein, putative	0.0056	0.007	0.3363
Echinococcus multilocularis	tyrosine protein kinase csk	0.0056	0.007	0.0084
Schistosoma mansoni	dynamin	0.0068	0.0097	0.0097
Trichomonas vaginalis	TKL family protein kinase	0.0056	0.007	0.0251
Trichomonas vaginalis	AGC family protein kinase	0.0087	0.0138	0.0686
Trichomonas vaginalis	conserved hypothetical protein	0.0745	0.1578	1
Leishmania major	protein kinase, putative	0.0074	0.0111	0.8039
Loa Loa (eye worm)	hypothetical protein	0.0162	0.0303	0.0303
Echinococcus multilocularis	oxysterol binding protein 9	0.0068	0.0097	0.0116
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0056	0.007	0.0084
Trichomonas vaginalis	conserved hypothetical protein	0.0162	0.0303	0.1756
Onchocerca volvulus		0.0034	0.0022	0.0069
Brugia malayi	RNA binding protein	0.0063	0.0085	0.0085
Entamoeba histolytica	hypothetical protein	0.0068	0.0097	0.0179
Loa Loa (eye worm)	G protein signaling regulator EGL-10	0.0745	0.1578	0.1578
Entamoeba histolytica	hypothetical protein, conserved domain containing	0.0068	0.0097	0.0179
Loa Loa (eye worm)	hypothetical protein	0.0056	0.007	0.007
Brugia malayi	hypothetical protein	0.0745	0.1578	0.1578
Echinococcus granulosus	tyrosine protein kinase Fps85D	0.0056	0.007	0.0084
Schistosoma mansoni	protein kinase	0.0056	0.007	0.007
Trichomonas vaginalis	TKL family protein kinase	0.0056	0.007	0.0251
Entamoeba histolytica	PH domain containing protein kinase, putative	0.0087	0.0138	0.0446
Loa Loa (eye worm)	syntrophin-1	0.0068	0.0097	0.0097
Trichomonas vaginalis	TKL family protein kinase	0.0056	0.007	0.0251
Brugia malayi	hypothetical protein	0.0116	0.0201	0.0201
Trichomonas vaginalis	AGC family protein kinase	0.0087	0.0138	0.0686
Trichomonas vaginalis	D-aminoacylase, putative	0.004	0.0036	0.003
Echinococcus multilocularis	raf serine:threonine protein kinase	0.0056	0.007	0.0084
Schistosoma mansoni	tyrosine protein kinase	0.0056	0.007	0.007
Trypanosoma cruzi	PH domain containing protein, putative	0.0068	0.0097	0.6027
Brugia malayi	Probable tyrosine-protein kinase kin-31	0.0056	0.007	0.007
Schistosoma mansoni	goodpasture antigen-binding protein	0.0068	0.0097	0.0097
Loa Loa (eye worm)	hypothetical protein	0.0111	0.019	0.019
Echinococcus granulosus	tyrosine protein kinase Btk29A	0.0056	0.007	0.0084
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0116	0.0201	0.0201
Plasmodium falciparum	conserved Plasmodium protein, unknown function	0.0068	0.0097	0.7075
Trichomonas vaginalis	TKL family protein kinase	0.0056	0.007	0.0251
Trichomonas vaginalis	conserved hypothetical protein	0.0162	0.0303	0.1756
Schistosoma mansoni	tar DNA-binding protein	0.0063	0.0085	0.0085
Loa Loa (eye worm)	RhoGEF domain-containing protein	0.0068	0.0097	0.0097
Echinococcus multilocularis	tyrosine protein kinase Abl	0.0056	0.007	0.0084
Schistosoma mansoni	protein kinase	0.0056	0.007	0.007
Mycobacterium tuberculosis	NAD(P)H quinone reductase LpdA	0.0125	0.022	0.3857
Brugia malayi	Protein kinase domain containing protein	0.0056	0.007	0.007
Echinococcus multilocularis	mitogen activated protein kinase kinase kinase	0.0056	0.007	0.0084
Onchocerca volvulus	outspread protein homolog	0.0068	0.0097	0.0476
Echinococcus multilocularis	retinal guanylyl cyclase 2	0.0056	0.007	0.0084
Loa Loa (eye worm)	TAR-binding protein	0.0063	0.0085	0.0085
Echinococcus multilocularis	tyrosine kinase	0.0056	0.007	0.0084
Brugia malayi	Oxysterol-binding protein	0.0068	0.0097	0.0097
Toxoplasma gondii	calcium dependent protein kinase CDPK7	0.0087	0.0138	1
Brugia malayi	Cadps2 protein	0.0068	0.0097	0.0097
Trichomonas vaginalis	TKL family protein kinase	0.0056	0.007	0.0251
Brugia malayi	PH domain containing protein	0.0068	0.0097	0.0097
Echinococcus granulosus	beta-adrenergic receptor kinase	0.3524	0.7653	0.9143
Brugia malayi	Protein kinase domain containing protein	0.0056	0.007	0.007
Loa Loa (eye worm)	TK protein kinase	0.0056	0.007	0.007
Echinococcus multilocularis	FERM and pleckstrin domain containing protein	0.0068	0.0097	0.0116
Brugia malayi	Protein kinase domain containing protein	0.0056	0.007	0.007
Echinococcus multilocularis	tyrosine protein kinase Src42A	0.0056	0.007	0.0084
Brugia malayi	Protein kinase domain containing protein	0.0056	0.007	0.007
Loa Loa (eye worm)	hypothetical protein	0.0745	0.1578	0.1578
Schistosoma mansoni	oxysterol-binding protein 1	0.0068	0.0097	0.0097
Brugia malayi	Protein kinase domain containing protein	0.0056	0.007	0.007
Loa Loa (eye worm)	TKL/MLK/ILK protein kinase	0.0056	0.007	0.007
Brugia malayi	Protein kinase domain containing protein	0.0056	0.007	0.007
Echinococcus granulosus	pleckstrin y domain containing family A	0.0068	0.0097	0.0116
Loa Loa (eye worm)	TK/ROR protein kinase	0.0056	0.007	0.007
Onchocerca volvulus		0.0068	0.0097	0.0476
Brugia malayi	Sema domain containing protein	0.0371	0.0759	0.0759
Brugia malayi	hypothetical protein	0.0371	0.0759	0.0759
Loa Loa (eye worm)	RGC/RGC protein kinase	0.0056	0.007	0.007
Schistosoma mansoni	tyrosine kinase	0.0056	0.007	0.007
Echinococcus granulosus	tyrosine kinase	0.0056	0.007	0.0084
Loa Loa (eye worm)	hypothetical protein	0.0028	0.0009	0.0009
Trichomonas vaginalis	AGC family protein kinase	0.0087	0.0138	0.0686
Toxoplasma gondii	Oxysterol-binding protein	0.0068	0.0097	0.7075
Schistosoma mansoni	rho gtpase activating protein	0.0068	0.0097	0.0097
Loa Loa (eye worm)	TK protein kinase	0.0056	0.007	0.007
Loa Loa (eye worm)	variant SH3 domain-containing protein	0.0068	0.0097	0.0097
Echinococcus multilocularis	arf GAP with coiled coil, ANK repeat and PH	0.0068	0.0097	0.0116
Toxoplasma gondii	aurora kinase	0.0078	0.0119	0.8643
Onchocerca volvulus		0.0056	0.007	0.033
Loa Loa (eye worm)	RGC/RGC protein kinase	0.0056	0.007	0.007
Echinococcus granulosus	tyrosine protein kinase Src64B	0.0056	0.007	0.0084
Echinococcus granulosus	tyrosine protein kinase HCK	0.0056	0.007	0.0084
Brugia malayi	Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative	0.004	0.0036	0.0036
Onchocerca volvulus	Putative zinc finger protein	0.0068	0.0097	0.0476
Echinococcus multilocularis	tyrosine protein kinase csk	0.0056	0.007	0.0084
Echinococcus multilocularis	cytohesin 1	0.0068	0.0097	0.0116
Echinococcus multilocularis	actin binding protein anillin	0.0068	0.0097	0.0116
Brugia malayi	Raf kinase	0.0056	0.007	0.007
Echinococcus granulosus	tyrosine protein kinase Lyn	0.0074	0.0111	0.0132
Echinococcus granulosus	tyrosine protein kinase Fyn	0.0056	0.007	0.0084
Onchocerca volvulus		0.0056	0.007	0.033
Loa Loa (eye worm)	TK protein kinase	0.0056	0.007	0.007
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0056	0.007	0.0084
Schistosoma mansoni	hypothetical protein	0.0162	0.0303	0.0303
Echinococcus multilocularis	retinal guanylyl cyclase 2	0.0056	0.007	0.0084
Trichomonas vaginalis	TKL family protein kinase	0.0056	0.007	0.0251
Echinococcus granulosus	retinal guanylyl cyclase 2	0.0056	0.007	0.0084
Loa Loa (eye worm)	hypothetical protein	0.0068	0.0097	0.0097
Entamoeba histolytica	Rho guanine nucleotide exchange factor, putative	0.0068	0.0097	0.0179
Trichomonas vaginalis	AGC family protein kinase	0.0087	0.0138	0.0686
Trichomonas vaginalis	TKL family protein kinase	0.0056	0.007	0.0251
Echinococcus multilocularis	tyrosine protein kinase csk	0.0056	0.007	0.0084
Trichomonas vaginalis	conserved hypothetical protein	0.0068	0.0097	0.0426
Echinococcus multilocularis	myotubularin protein 13	0.0068	0.0097	0.0116
Echinococcus granulosus	serine/threonine protein kinase	0.0087	0.0138	0.0165
Echinococcus multilocularis	G protein coupled receptor kinase 1	0.2779	0.6023	0.7196
Onchocerca volvulus		0.004	0.0036	0.0146
Trichomonas vaginalis	TKL family protein kinase	0.0056	0.007	0.0251
Loa Loa (eye worm)	glutathione reductase	0.0049	0.0055	0.0055
Onchocerca volvulus	Atrial natriuretic peptide receptor 3 homolog	0.0056	0.007	0.033
Echinococcus granulosus	oxysterol binding protein 3	0.0068	0.0097	0.0116
Onchocerca volvulus		0.0056	0.007	0.033
Brugia malayi	Tyrosine-protein kinase PR2	0.0056	0.007	0.007
Trichomonas vaginalis	conserved hypothetical protein	0.0068	0.0097	0.0426
Brugia malayi	Protein kinase domain containing protein	0.0056	0.007	0.007
Loa Loa (eye worm)	AGC/GRK/GRK protein kinase	0.4597	1	1
Trichomonas vaginalis	AGC family protein kinase	0.0087	0.0138	0.0686
Loa Loa (eye worm)	TK/FER protein kinase	0.0056	0.007	0.007
Brugia malayi	Thioredoxin reductase	0.0049	0.0055	0.0055
Leishmania major	hypothetical protein, conserved	0.0068	0.0097	0.7075
Trichomonas vaginalis	conserved hypothetical protein	0.0162	0.0303	0.1756
Trypanosoma cruzi	serine/threonine protein kinase, putative	0.0087	0.0138	1
Schistosoma mansoni	z-protein (S1r protein)	0.0745	0.1578	0.1578
Loa Loa (eye worm)	hypothetical protein	0.0111	0.019	0.019
Trichomonas vaginalis	conserved hypothetical protein	0.0068	0.0097	0.0426
Plasmodium vivax	thioredoxin reductase, putative	0.0049	0.0055	0.1868
Mycobacterium tuberculosis	Putative ferredoxin reductase	0.0112	0.0193	0.3284
Echinococcus multilocularis	regulator of G protein signaling 7	0.0745	0.1578	0.1885
Brugia malayi	Protein kinase domain containing protein	0.0056	0.007	0.007
Echinococcus multilocularis	tyrosine protein kinase lyn tyrosine protein kinase blk	0.0056	0.007	0.0084
Loa Loa (eye worm)	plexin A	0.1036	0.2214	0.2214
Loa Loa (eye worm)	TK/KIN6 protein kinase	0.0056	0.007	0.007
Trichomonas vaginalis	TKL family protein kinase	0.0056	0.007	0.0251
Loa Loa (eye worm)	hypothetical protein	0.0745	0.1578	0.1578
Trypanosoma cruzi	Serine/threonine-protein kinase NEK21, putative	0.0087	0.0138	1
Trichomonas vaginalis	TKL family protein kinase	0.0056	0.007	0.0251
Trichomonas vaginalis	AGC family protein kinase	0.0087	0.0138	0.0686
Echinococcus multilocularis	axis inhibition protein axin	0.0745	0.1578	0.1885
Schistosoma mansoni	regulator of G protein signaling	0.0745	0.1578	0.1578
Loa Loa (eye worm)	hypothetical protein	0.0213	0.0414	0.0414
Loa Loa (eye worm)	protein kinase domain-containing protein	0.0056	0.007	0.007
Brugia malayi	PH domain containing protein	0.0068	0.0097	0.0097
Loa Loa (eye worm)	TK protein kinase	0.0056	0.007	0.007
Loa Loa (eye worm)	TK/FER protein kinase	0.0056	0.007	0.007
Entamoeba histolytica	p21-activated kinase	0.0087	0.0138	0.0446
Loa Loa (eye worm)	hypothetical protein	0.0029	0.0011	0.0011
Loa Loa (eye worm)	hypothetical protein	0.0068	0.0097	0.0097
Brugia malayi	Tyrosine-protein kinase F09A5.2 in chromosome X, putative	0.0056	0.007	0.007
Brugia malayi	PXA domain containing protein	0.0745	0.1578	0.1578
Trichomonas vaginalis	conserved hypothetical protein	0.0056	0.007	0.0251
Trichomonas vaginalis	AGC family protein kinase	0.0087	0.0138	0.0686
Echinococcus multilocularis	Pleckstrin y	0.0068	0.0097	0.0116
Trichomonas vaginalis	TKL family protein kinase	0.0056	0.007	0.0251
Onchocerca volvulus	Tyrosine kinase homolog	0.0056	0.007	0.033
Trichomonas vaginalis	conserved hypothetical protein	0.0068	0.0097	0.0426
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	0.01	0.0167	0.02
Trichomonas vaginalis	AGC family protein kinase	0.0087	0.0138	0.0686
Entamoeba histolytica	hypothetical protein	0.0087	0.0138	0.0446
Onchocerca volvulus		0.0068	0.0097	0.0476
Echinococcus granulosus	thioredoxin glutathione reductase	0.0049	0.0055	0.0066
Entamoeba histolytica	hypothetical protein, conserved domain containing	0.0068	0.0097	0.0179
Schistosoma mansoni	tyrosine kinase	0.0056	0.007	0.007
Trichomonas vaginalis	Clan MA, family M8, leishmanolysin-like metallopeptidase	0.0162	0.0303	0.1756
Echinococcus multilocularis	heat shock protein 70	0.0056	0.007	0.0084
Trypanosoma brucei	protein kinase, putative	0.0074	0.0111	0.7336
Schistosoma mansoni	serine/threonine-protein kinase	0.0087	0.0138	0.0138
Loa Loa (eye worm)	hypothetical protein	0.004	0.0036	0.0036
Onchocerca volvulus		0.0056	0.007	0.033
Plasmodium falciparum	protein kinase, putative	0.0056	0.007	0.5114
Trichomonas vaginalis	ankyrin 2,3/unc44, putative	0.0068	0.0097	0.0426
Trichomonas vaginalis	D-aminoacylase, putative	0.004	0.0036	0.003
Entamoeba histolytica	protein kinase domain containing protein	0.0218	0.0426	0.2357
Brugia malayi	Protein kinase domain containing protein	0.0056	0.007	0.007
Brugia malayi	GTPase-activator protein for Ras-like GTPase containing protein	0.0068	0.0097	0.0097
Trichomonas vaginalis	centaurin gamma, putative	0.0068	0.0097	0.0426
Trichomonas vaginalis	TKL family protein kinase	0.0056	0.007	0.0251
Schistosoma mansoni	tyrosine kinase	0.0056	0.007	0.007
Echinococcus granulosus	cytohesin 1	0.0068	0.0097	0.0116
Schistosoma mansoni	goodpasture antigen-binding protein	0.0068	0.0097	0.0097
Echinococcus granulosus	integrin linked protein kinase	0.0056	0.007	0.0084
Schistosoma mansoni	serine/threonine protein kinase	0.4597	1	1
Trichomonas vaginalis	D-aminoacylase, putative	0.004	0.0036	0.003
Trichomonas vaginalis	TKL family protein kinase	0.0056	0.007	0.0251
Echinococcus granulosus	calcium dependent secretion activator 1	0.0068	0.0097	0.0116
Echinococcus multilocularis	c src tyrosine kinase	0.0056	0.007	0.0084
Plasmodium vivax	hypothetical protein, conserved	0.0068	0.0097	0.6027
Trichomonas vaginalis	TKL family protein kinase	0.0056	0.007	0.0251
Trypanosoma cruzi	STE/STE11 serine/threonine-protein kinase, putative	0.0074	0.0111	0.7336
Loa Loa (eye worm)	hypothetical protein	0.0745	0.1578	0.1578
Trichomonas vaginalis	TKL family protein kinase	0.0056	0.007	0.0251
Trichomonas vaginalis	conserved hypothetical protein	0.0745	0.1578	1
Loa Loa (eye worm)	hypothetical protein	0.0162	0.0303	0.0303
Loa Loa (eye worm)	TKL/STKR/TYPE1 protein kinase	0.0056	0.007	0.007
Mycobacterium ulcerans	beta-lactamase	0.004	0.0036	0.5
Echinococcus multilocularis	Rho GTPase activating protein 24	0.0068	0.0097	0.0116
Mycobacterium tuberculosis	Probable NADH dehydrogenase Ndh	0.0112	0.0193	0.3284
Trichomonas vaginalis	TKL family protein kinase	0.0056	0.007	0.0251
Loa Loa (eye worm)	pigment dispersing factor receptor c	0.0049	0.0056	0.0056
Brugia malayi	Protein kinase domain containing protein	0.0056	0.007	0.007
Loa Loa (eye worm)	TK/FER protein kinase	0.0056	0.007	0.007
Echinococcus granulosus	G protein coupled receptor kinase 1	0.2779	0.6023	0.7196
Trypanosoma brucei	trypanothione reductase	0.0049	0.0055	0.1868
Echinococcus multilocularis	Arf GAP and Pleckstrin domain containing protein	0.0068	0.0097	0.0116
Echinococcus multilocularis	axis inhibition protein axin	0.0745	0.1578	0.1885
Entamoeba histolytica	pleckstrin homology (PH) domain containing protein	0.0068	0.0097	0.0179
Schistosoma mansoni	tyrosine kinase	0.0056	0.007	0.007
Echinococcus multilocularis	tyrosine protein kinase	0.0056	0.007	0.0084
Echinococcus granulosus	proto oncogene tyrosine protein kinase LCK	0.0056	0.007	0.0084
Entamoeba histolytica	PH domain containing protein kinase, putative	0.0087	0.0138	0.0446
Schistosoma mansoni	hypothetical protein	0.0068	0.0097	0.0097
Toxoplasma gondii	protein kinase domain-containing protein	0.0056	0.007	0.5114
Trichomonas vaginalis	conserved hypothetical protein	0.0056	0.007	0.0251
Trypanosoma brucei	Flagellum attachment zone protein 20	0.0056	0.007	0.3363
Echinococcus granulosus	mitogen activated protein kinase kinase kinase	0.0056	0.007	0.0084
Plasmodium falciparum	tyrosine kinase-like protein	0.0056	0.007	0.5114
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0167	0.0312	0.0312
Schistosoma mansoni	protein kinase	0.0074	0.0111	0.0111
Echinococcus granulosus	activated cdc42 kinase 1	0.0056	0.007	0.0084
Schistosoma mansoni	proto-oncogene tyrosine-protein kinase src	0.0056	0.007	0.007
Trichomonas vaginalis	TKL family protein kinase	0.0056	0.007	0.0251
Plasmodium falciparum	thioredoxin reductase	0.0049	0.0055	0.4013
Brugia malayi	Protein kinase domain containing protein	0.0056	0.007	0.007
Entamoeba histolytica	PH domain containing protein kinase, putative	0.0087	0.0138	0.0446
Echinococcus granulosus	MAM	0.0029	0.0011	0.0013
Echinococcus multilocularis	natriuretic peptide receptor 1	0.0056	0.007	0.0084
Schistosoma mansoni	nephrin	0.0116	0.0201	0.0201
Onchocerca volvulus	Protein melted homolog	0.0068	0.0097	0.0476
Loa Loa (eye worm)	hypothetical protein	0.0111	0.019	0.019
Loa Loa (eye worm)	beta-lactamase	0.004	0.0036	0.0036
Giardia lamblia	Aurora kinase	0.0078	0.0119	1
Echinococcus multilocularis	protein tyrosine kinase	0.0056	0.007	0.0084
Trichomonas vaginalis	TKL family protein kinase	0.0056	0.007	0.0251
Loa Loa (eye worm)	hypothetical protein	0.0158	0.0292	0.0292
Schistosoma mansoni	hypothetical protein	0.0503	0.1048	0.1048
Schistosoma mansoni	defective proboscis extension response (dpr)-related	0.0111	0.019	0.019
Echinococcus granulosus	axis inhibition protein axin	0.0745	0.1578	0.1885
Echinococcus granulosus	geminin	0.0534	0.1115	0.1332
Echinococcus granulosus	natriuretic peptide receptor 1	0.0056	0.007	0.0084
Schistosoma mansoni	hypothetical protein	0.0162	0.0303	0.0303
Echinococcus granulosus	dual specificity testis-specific protein kinase	0.0074	0.0111	0.0132
Trichomonas vaginalis	AGC family protein kinase	0.0078	0.0119	0.0565
Schistosoma mansoni	hypothetical protein	0.0534	0.1115	0.1115
Echinococcus multilocularis	beta adrenergic receptor kinase	0.3524	0.7653	0.9143
Trichomonas vaginalis	TKL family protein kinase	0.0056	0.007	0.0251
Brugia malayi	beta-lactamase family protein	0.004	0.0036	0.0036
Echinococcus multilocularis	insulin receptor	0.0056	0.007	0.0084
Echinococcus granulosus	Pleckstrin y	0.0068	0.0097	0.0116
Brugia malayi	Sema domain containing protein	0.0371	0.0759	0.0759
Echinococcus granulosus	tyrosine protein kinase transmembrane receptor	0.0056	0.007	0.0084
Echinococcus multilocularis	transcription factor collier	0.0162	0.0303	0.0362
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	0.01	0.0167	0.02
Trichomonas vaginalis	ankyrin repeat-containing protein, putative	0.0068	0.0097	0.0426
Brugia malayi	RNA recognition motif domain containing protein	0.0063	0.0085	0.0085
Brugia malayi	hypothetical protein	0.0056	0.007	0.007
Echinococcus granulosus	axis inhibition protein axin	0.0745	0.1578	0.1885
Trichomonas vaginalis	TKL family protein kinase	0.0056	0.007	0.0251
Schistosoma mansoni	tar DNA-binding protein	0.0063	0.0085	0.0085
Echinococcus multilocularis	tyrosine protein kinase transmembrane receptor	0.0056	0.007	0.0084
Schistosoma mansoni	syntrophin	0.0068	0.0097	0.0097
Trichomonas vaginalis	TKL family protein kinase	0.0056	0.007	0.0251
Loa Loa (eye worm)	hypothetical protein	0.0056	0.007	0.007
Schistosoma mansoni	tyrosine kinase	0.0056	0.007	0.007
Echinococcus multilocularis	regulator of G protein signaling 3	0.0745	0.1578	0.1885
Trichomonas vaginalis	TKL family protein kinase	0.0056	0.007	0.0251
Brugia malayi	Regulator of G protein signaling domain containing protein	0.0745	0.1578	0.1578
Echinococcus granulosus	plexin a4	0.1036	0.2214	0.2645
Leishmania major	rac serine-threonine kinase, putative,protein kinase, putative	0.0087	0.0138	1
Echinococcus granulosus	tyrosine protein kinase Fyn	0.0056	0.007	0.0084
Loa Loa (eye worm)	TK/EPH protein kinase	0.0056	0.007	0.007
Plasmodium vivax	protein kinase, putative	0.0056	0.007	0.3363
Echinococcus multilocularis	atrial natriuretic peptide receptor 1	0.0056	0.007	0.0084
Entamoeba histolytica	Rho guanine nucleotide exchange factor, putative	0.0068	0.0097	0.0179
Loa Loa (eye worm)	hypothetical protein	0.0068	0.0097	0.0097
Trypanosoma cruzi	hypothetical protein	0.0068	0.0097	0.6027
Brugia malayi	PH domain containing protein	0.0068	0.0097	0.0097
Echinococcus granulosus	insulin growth factor 1 receptor beta	0.0061	0.0081	0.0097
Schistosoma mansoni	protein kinase	0.0056	0.007	0.007
Loa Loa (eye worm)	hypothetical protein	0.0745	0.1578	0.1578
Echinococcus multilocularis	tyrosine protein kinase pr2	0.0056	0.007	0.0084
Onchocerca volvulus		0.0874	0.1859	1
Brugia malayi	serine/threonine protein kinase 6	0.0078	0.0119	0.0119
Loa Loa (eye worm)	hypothetical protein	0.0371	0.0759	0.0759
Trichomonas vaginalis	conserved hypothetical protein	0.0745	0.1578	1
Brugia malayi	Tyrosine-protein kinase abl-1	0.0056	0.007	0.007
Trichomonas vaginalis	conserved hypothetical protein	0.0745	0.1578	1
Brugia malayi	PH domain containing protein	0.0068	0.0097	0.0097
Brugia malayi	IPT/TIG domain containing protein	0.0162	0.0303	0.0303
Trichomonas vaginalis	TKL family protein kinase	0.0056	0.007	0.0251
Echinococcus granulosus	arf GAP with coiled coil ANK repeat and PH	0.0068	0.0097	0.0116
Schistosoma mansoni	tyrosine kinase	0.0056	0.007	0.007
Schistosoma mansoni	regulator of G protein signaling	0.0745	0.1578	0.1578
Loa Loa (eye worm)	hypothetical protein	0.0068	0.0097	0.0097
Echinococcus granulosus	kinase suppressor of Ras 1	0.0056	0.007	0.0084
Entamoeba histolytica	Rho guanine nucleotide exchange factor, putative	0.0068	0.0097	0.0179
Echinococcus granulosus	[G-protein-coupledreceptor] kinase	0.3852	0.837	1
Echinococcus multilocularis	beta LACTamase domain containing family member	0.004	0.0036	0.0043
Trichomonas vaginalis	TKL family protein kinase	0.0056	0.007	0.0251
Schistosoma mansoni	tar DNA-binding protein	0.0063	0.0085	0.0085
Loa Loa (eye worm)	AGC/GRK/GRK protein kinase	0.3852	0.837	0.837
Schistosoma mansoni	protein kinase	0.0056	0.007	0.007
Entamoeba histolytica	Rho guanine nucleotide exchange factor, putative	0.0068	0.0097	0.0179
Trypanosoma brucei	PH domain containing protein, putative	0.0068	0.0097	0.6027
Loa Loa (eye worm)	TK protein kinase	0.0056	0.007	0.007
Echinococcus granulosus	semaphorin 5B	0.0371	0.0759	0.0906
Trypanosoma brucei	serine/threonine-protein kinase NrkA	0.0087	0.0138	1
Schistosoma mansoni	proto-oncogene tyrosine-protein kinase src	0.0056	0.007	0.007
Trichomonas vaginalis	ankyrin repeat-containing protein, putative	0.0056	0.007	0.0251
Plasmodium falciparum	PH domain-containing protein, putative	0.0068	0.0097	0.7075
Trichomonas vaginalis	conserved hypothetical protein	0.0068	0.0097	0.0426
Onchocerca volvulus		0.0158	0.0292	0.153
Loa Loa (eye worm)	hypothetical protein	0.0068	0.0097	0.0097
Echinococcus granulosus	tyrosine protein kinase Blk	0.0056	0.007	0.0084
Schistosoma mansoni	lamin	0.0028	0.0009	0.0009
Brugia malayi	Receptor family ligand binding region containing protein	0.0056	0.007	0.007
Echinococcus granulosus	epidermal growth factor receptor	0.0056	0.007	0.0084
Trichomonas vaginalis	AGC family protein kinase	0.0087	0.0138	0.0686
Trichomonas vaginalis	AGC family protein kinase	0.0087	0.0138	0.0686
Schistosoma mansoni	regulator of G protein signaling	0.0745	0.1578	0.1578
Echinococcus multilocularis	fibroblast growth factor receptor 4	0.0056	0.007	0.0084
Echinococcus multilocularis	lamin dm0	0.0028	0.0009	0.0011
Loa Loa (eye worm)	TK/CSK protein kinase	0.0056	0.007	0.007
Brugia malayi	hypothetical protein	0.0371	0.0759	0.0759
Echinococcus granulosus	semaphorin 1A	0.0371	0.0759	0.0906
Trichomonas vaginalis	conserved hypothetical protein	0.0068	0.0097	0.0426
Echinococcus multilocularis	ras specific guanine nucleotide releasing factor	0.0068	0.0097	0.0116
Loa Loa (eye worm)	hypothetical protein	0.0068	0.0097	0.0097
Plasmodium falciparum	glutathione reductase	0.0049	0.0055	0.4013
Onchocerca volvulus		0.0068	0.0097	0.0476
Schistosoma mansoni	protein kinase	0.0056	0.007	0.007
Schistosoma mansoni	tyrosine kinase	0.0056	0.007	0.007
Onchocerca volvulus		0.0056	0.007	0.033
Trichomonas vaginalis	Clan MA, family M8, leishmanolysin-like metallopeptidase	0.0162	0.0303	0.1756
Schistosoma mansoni	tyrosine kinase	0.0056	0.007	0.007
Echinococcus granulosus	Pleckstrin y	0.0068	0.0097	0.0116
Loa Loa (eye worm)	hypothetical protein	0.0068	0.0097	0.0097
Loa Loa (eye worm)	hypothetical protein	0.0056	0.007	0.007
Trichomonas vaginalis	conserved hypothetical protein	0.0162	0.0303	0.1756
Brugia malayi	Protein kinase domain containing protein	0.0056	0.007	0.007
Echinococcus granulosus	ephrin type A receptor 4 A	0.0056	0.007	0.0084
Loa Loa (eye worm)	voltage and ligand gated potassium channel	0.0041	0.0038	0.0038
Loa Loa (eye worm)	TK/KIN16 protein kinase	0.0167	0.0312	0.0312
Loa Loa (eye worm)	intermediate filament tail domain-containing protein	0.0028	0.0009	0.0009
Schistosoma mansoni	tyrosine kinase	0.0056	0.007	0.007
Trichomonas vaginalis	conserved hypothetical protein	0.0745	0.1578	1
Echinococcus multilocularis	Ras associated and pleckstrin y	0.0068	0.0097	0.0116
Mycobacterium tuberculosis	Probable dehydrogenase	0.0112	0.0193	0.3284
Plasmodium vivax	serine/threonine protein kinase 6, putative	0.0078	0.0119	0.8157
Brugia malayi	hypothetical protein	0.0056	0.007	0.007
Trypanosoma cruzi	PH domain containing protein, putative	0.0068	0.0097	0.6027
Schistosoma mansoni	serine/threonine protein kinase	0.0056	0.007	0.007
Echinococcus multilocularis	tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase	0.0056	0.007	0.0084
Schistosoma mansoni	semaphorin 5-related	0.0371	0.0759	0.0759
Echinococcus granulosus	myotubularin protein 13	0.0068	0.0097	0.0116
Brugia malayi	GTP-binding regulatory protein Gs alpha-S chain, putative	0.01	0.0167	0.0167
Trypanosoma brucei	NEK family Serine/threonine-protein kinase, putative	0.0087	0.0138	1
Brugia malayi	Protein kinase domain containing protein	0.0056	0.007	0.007
Leishmania major	hypothetical protein, conserved	0.004	0.0036	0.2637
Schistosoma mansoni	tyrosine kinase	0.0056	0.007	0.007
Schistosoma mansoni	tyrosine kinase	0.0056	0.007	0.007
Loa Loa (eye worm)	hypothetical protein	0.0056	0.007	0.007
Loa Loa (eye worm)	hypothetical protein	0.004	0.0036	0.0036
Loa Loa (eye worm)	hypothetical protein	0.0745	0.1578	0.1578
Echinococcus granulosus	type II inositol 34 bisphosphate 4 phosphatase	0.0068	0.0097	0.0116
Schistosoma mansoni	plexin	0.0874	0.1859	0.1859
Brugia malayi	PH domain containing protein	0.0068	0.0097	0.0097
Leishmania major	hypothetical protein, conserved	0.0056	0.007	0.5114
Echinococcus multilocularis	protein KINase family member (kin 25)	0.0056	0.007	0.0084
Loa Loa (eye worm)	hypothetical protein	0.0056	0.007	0.007
Loa Loa (eye worm)	hypothetical protein	0.0111	0.019	0.019
Echinococcus multilocularis	Immunoglobulin	0.0111	0.019	0.0227
Toxoplasma gondii	protein kinase	0.0056	0.007	0.5114
Schistosoma mansoni	intermediate filament proteins	0.0028	0.0009	0.0009
Schistosoma mansoni	ephrin receptor	0.0056	0.007	0.007
Schistosoma mansoni	myotubularin-related protein	0.0068	0.0097	0.0097
Trichomonas vaginalis	TKL family protein kinase	0.0056	0.007	0.0251
Plasmodium vivax	tyrosine kinase-like protein, putative	0.0056	0.007	0.3363
Loa Loa (eye worm)	hypothetical protein	0.0036	0.0026	0.0026
Loa Loa (eye worm)	hypothetical protein	0.0874	0.1859	0.1859
Echinococcus multilocularis	Immunoglobulin	0.0111	0.019	0.0227
Entamoeba histolytica	Rho guanine nucleotide exchange factor, putative	0.0068	0.0097	0.0179
Schistosoma mansoni	tyrosine protein kinase fes (fps) (ptk group IV)	0.0056	0.007	0.007
Brugia malayi	Protein kinase domain containing protein	0.0056	0.007	0.007
Entamoeba histolytica	PH domain containing protein kinase, putative	0.0087	0.0138	0.0446
Schistosoma mansoni	zinc finger protein	0.0068	0.0097	0.0097
Echinococcus granulosus	tyrosine protein kinase Btk29A	0.0056	0.007	0.0084
Loa Loa (eye worm)	SRC-1	0.0056	0.007	0.007
Loa Loa (eye worm)	hypothetical protein	0.0056	0.007	0.007
Loa Loa (eye worm)	hypothetical protein	0.0034	0.0022	0.0022
Trichomonas vaginalis	protein transport protein sec7, putative	0.0068	0.0097	0.0426
Trichomonas vaginalis	conserved hypothetical protein	0.0068	0.0097	0.0426
Echinococcus multilocularis	tyrosine protein kinase Srms	0.0056	0.007	0.0084
Echinococcus granulosus	3'partial\|tyrosine protein kinase Fgr	0.0056	0.007	0.0084
Brugia malayi	latrophilin 2 splice variant baaae	0.0034	0.0022	0.0022
Trichomonas vaginalis	TK family protein kinase	0.0056	0.007	0.0251
Echinococcus multilocularis	arf GAP with SH3 domain, ANK repeat and PH	0.0068	0.0097	0.0116
Echinococcus multilocularis	ephrin type A receptor 4 A	0.0056	0.007	0.0084
Brugia malayi	beta-lactamase	0.004	0.0036	0.0036
Entamoeba histolytica	protein kinase, putative	0.0078	0.0119	0.0322
Trichomonas vaginalis	AGC family protein kinase	0.0087	0.0138	0.0686
Trichomonas vaginalis	TKL family protein kinase	0.0056	0.007	0.0251
Echinococcus multilocularis	Pleckstrin y	0.0068	0.0097	0.0116
Toxoplasma gondii	STE kinase	0.0056	0.007	0.5114
Trichomonas vaginalis	protein kinase atn1, putative	0.0056	0.007	0.0251
Schistosoma mansoni	hypothetical protein	0.0029	0.0011	0.0011
Trichomonas vaginalis	TKL family protein kinase	0.0056	0.007	0.0251
Brugia malayi	serine/threonine kinase 12	0.0078	0.0119	0.0119
Loa Loa (eye worm)	TK/FER protein kinase	0.0056	0.007	0.007
Loa Loa (eye worm)	TK/FER protein kinase	0.0056	0.007	0.007
Brugia malayi	Protein kinase domain containing protein	0.0056	0.007	0.007
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	0.01	0.0167	0.02
Trypanosoma cruzi	hypothetical protein	0.0068	0.0097	0.6027
Trichomonas vaginalis	penicillin-binding protein, putative	0.004	0.0036	0.003
Brugia malayi	Protein kinase domain containing protein	0.0056	0.007	0.007
Loa Loa (eye worm)	hypothetical protein	0.0068	0.0097	0.0097
Brugia malayi	Protein kinase domain containing protein	0.0056	0.007	0.007
Trypanosoma brucei	rac serine-threonine kinase, putative	0.0087	0.0138	1
Toxoplasma gondii	Tyrosine kinase-like (TKL) protein	0.0056	0.007	0.5114
Echinococcus granulosus	insulin receptor	0.0056	0.007	0.0084
Loa Loa (eye worm)	hypothetical protein	0.0371	0.0759	0.0759
Loa Loa (eye worm)	hypothetical protein	0.0068	0.0097	0.0097
Trichomonas vaginalis	penicillin-binding protein, putative	0.004	0.0036	0.003
Trypanosoma cruzi	NEK family Serine/threonine-protein kinase, putative	0.0087	0.0138	1
Trypanosoma cruzi	protein kinase, putative	0.0056	0.007	0.3363
Onchocerca volvulus		0.0068	0.0097	0.0476
Brugia malayi	SH2 domain containing protein	0.0056	0.007	0.007
Loa Loa (eye worm)	TK/FER protein kinase	0.0056	0.007	0.007
Echinococcus multilocularis	tyrosine protein kinase Fgr	0.0056	0.007	0.0084
Echinococcus multilocularis	GRB2 associated binding protein 3	0.0068	0.0097	0.0116
Trichomonas vaginalis	Clan MA, family M8, leishmanolysin-like metallopeptidase	0.0162	0.0303	0.1756
Schistosoma mansoni	oxysterol-binding protein 1	0.0068	0.0097	0.0097
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.01	0.0167	0.0167
Loa Loa (eye worm)	TK/FER protein kinase	0.0056	0.007	0.007
Trichomonas vaginalis	TKL family protein kinase	0.0056	0.007	0.0251
Schistosoma mansoni	tyrosine protein kinase fes (fps) (ptk group IV)	0.0056	0.007	0.007
Echinococcus multilocularis	protein kinase	0.0056	0.007	0.0084
Brugia malayi	Adenylate and Guanylate cyclase catalytic domain containing protein	0.0056	0.007	0.007
Entamoeba histolytica	Rho guanine nucleotide exchange factor, putative	0.0068	0.0097	0.0179
Mycobacterium tuberculosis	Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras	0.0125	0.022	0.3857
Entamoeba histolytica	hypothetical protein	0.0162	0.0303	0.1544
Trypanosoma cruzi	PH domain containing protein, putative	0.0068	0.0097	0.6027
Echinococcus granulosus	tyrosine protein kinase Fes:Fps	0.0056	0.007	0.0084
Loa Loa (eye worm)	TK protein kinase	0.0056	0.007	0.007
Trichomonas vaginalis	TKL family protein kinase	0.0056	0.007	0.0251
Brugia malayi	intermediate filament protein	0.0028	0.0009	0.0009
Loa Loa (eye worm)	hypothetical protein	0.0371	0.0759	0.0759
Schistosoma mansoni	protein kinase	0.0056	0.007	0.007
Loa Loa (eye worm)	TK/FER protein kinase	0.0056	0.007	0.007
Schistosoma mansoni	dynamin	0.0068	0.0097	0.0097
Schistosoma mansoni	growth factor receptor-bound protein	0.0068	0.0097	0.0097
Brugia malayi	probable spectrin beta chain	0.0068	0.0097	0.0097
Schistosoma mansoni	hypothetical protein	0.0068	0.0097	0.0097
Brugia malayi	Guanylyl cyclase protein 23	0.0056	0.007	0.007
Echinococcus multilocularis	mitogen activated protein kinase kinase kinase	0.0056	0.007	0.0084
Entamoeba histolytica	protein kinase, putative	0.0087	0.0138	0.0446
Echinococcus multilocularis	transfer RNA-Thr	0.0056	0.007	0.0084
Echinococcus multilocularis	activated cdc42 kinase 1	0.0056	0.007	0.0084
Leishmania major	folate/biopterin transporter, putative	0.0087	0.0138	1
Loa Loa (eye worm)	RNA binding protein	0.0063	0.0085	0.0085
Trypanosoma cruzi	hypothetical protein	0.0068	0.0097	0.6027
Echinococcus multilocularis	insulin growth factor 1 receptor beta	0.0061	0.0081	0.0097
Brugia malayi	DNA-binding protein LAG-1	0.0162	0.0303	0.0303
Schistosoma mansoni	hypothetical protein	0.0068	0.0097	0.0097
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.01	0.0167	0.0167
Echinococcus granulosus	lamin	0.0028	0.0009	0.0011
Trichomonas vaginalis	conserved hypothetical protein	0.0068	0.0097	0.0426
Echinococcus granulosus	macrophage colony stimulating factor 1 receptor	0.0056	0.007	0.0084
Loa Loa (eye worm)	hypothetical protein	0.0116	0.0201	0.0201
Echinococcus granulosus	melanoma receptor tyrosine protein kinase	0.0056	0.007	0.0084
Loa Loa (eye worm)	hypothetical protein	0.0116	0.0201	0.0201
Loa Loa (eye worm)	hypothetical protein	0.0056	0.007	0.007
Brugia malayi	regulator of G-protein signaling rgs-7	0.0745	0.1578	0.1578
Entamoeba histolytica	hypothetical protein, conserved domain containing	0.0068	0.0097	0.0179
Trypanosoma cruzi	hypothetical protein	0.0068	0.0097	0.6027
Trichomonas vaginalis	AGC family protein kinase	0.0087	0.0138	0.0686
Schistosoma mansoni	development and differentiation-enhancing factor ddef	0.0068	0.0097	0.0097
Loa Loa (eye worm)	hypothetical protein	0.0116	0.0201	0.0201
Entamoeba histolytica	Rho guanine nucleotide exchange factor, putative	0.0068	0.0097	0.0179
Echinococcus multilocularis	tyrosine protein kinase csk	0.0056	0.007	0.0084
Echinococcus multilocularis	basement membrane specific heparan sulfate	0.0111	0.019	0.0227
Echinococcus granulosus	dynamin 1	0.0068	0.0097	0.0116
Echinococcus multilocularis	integrin linked protein kinase	0.0056	0.007	0.0084
Entamoeba histolytica	serine/threonine- protein kinase 6 , putative	0.0078	0.0119	0.0322
Onchocerca volvulus		0.0029	0.0011	0.001
Echinococcus granulosus	tar DNA binding protein	0.0063	0.0085	0.0101
Echinococcus granulosus	basic fibroblast growth factor receptor 1 A	0.0056	0.007	0.0084
Loa Loa (eye worm)	PH domain-containing protein	0.0068	0.0097	0.0097
Loa Loa (eye worm)	hypothetical protein	0.0028	0.0008	0.0008
Entamoeba histolytica	hypothetical protein	0.0745	0.1578	1
Loa Loa (eye worm)	TK/FER protein kinase	0.0056	0.007	0.007
Mycobacterium ulcerans	hypothetical protein	0.004	0.0036	0.5
Onchocerca volvulus	Putative neuronal RhoA GEF protein	0.0068	0.0097	0.0476
Trichomonas vaginalis	AGC family protein kinase	0.0078	0.0119	0.0565
Trichomonas vaginalis	ankyrin repeat and FYVE domain containing protein, putative	0.0068	0.0097	0.0426
Entamoeba histolytica	protein kinase, putative	0.0087	0.0138	0.0446
Entamoeba histolytica	protein kinase , putative	0.0078	0.0119	0.0322
Trichomonas vaginalis	TKL family protein kinase	0.0056	0.007	0.0251
Schistosoma mansoni	hypothetical protein	0.0056	0.007	0.007
Schistosoma mansoni	vav2	0.0068	0.0097	0.0097
Loa Loa (eye worm)	intermediate filament protein	0.0028	0.0009	0.0009
Schistosoma mansoni	axis inhibition protein axin	0.0745	0.1578	0.1578
Entamoeba histolytica	hypothetical protein	0.0162	0.0303	0.1544
Trichomonas vaginalis	AGC family protein kinase	0.0087	0.0138	0.0686
Brugia malayi	ephrin receptor 1 precursor	0.0056	0.007	0.007
Schistosoma mansoni	hypothetical protein	0.0068	0.0097	0.0097
Entamoeba histolytica	hypothetical protein	0.0745	0.1578	1
Schistosoma mansoni	tyrosine kinase	0.0056	0.007	0.007
Schistosoma mansoni	tyrosine kinase	0.0056	0.007	0.007
Brugia malayi	Protein kinase domain containing protein	0.0056	0.007	0.007
Trichomonas vaginalis	TKL family protein kinase	0.0056	0.007	0.0251
Trichomonas vaginalis	AGC family protein kinase	0.0087	0.0138	0.0686
Echinococcus multilocularis	proto oncogene tyrosine protein kinase LCK	0.0056	0.007	0.0084
Schistosoma mansoni	tyrosine kinase	0.0056	0.007	0.007
Toxoplasma gondii	Tyrosine kinase-like (TKL) protein	0.0056	0.007	0.5114
Trypanosoma cruzi	NIMA-related kinase, putative	0.0087	0.0138	1
Trichomonas vaginalis	AGC family protein kinase	0.0087	0.0138	0.0686
Loa Loa (eye worm)	TK/EGFR protein kinase	0.0056	0.007	0.007
Echinococcus multilocularis	epidermal growth factor receptor	0.0056	0.007	0.0084
Mycobacterium tuberculosis	Probable oxidoreductase	0.0125	0.022	0.3857
Echinococcus multilocularis	retinal guanylyl cyclase 2	0.0056	0.007	0.0084
Entamoeba histolytica	ARF GTPase activating protein, putative	0.0068	0.0097	0.0179
Echinococcus granulosus	regulator of G protein signaling 7	0.0745	0.1578	0.1885
Schistosoma mansoni	voltage-gated potassium channel	0.0045	0.0046	0.0046
Loa Loa (eye worm)	TK/FER protein kinase	0.0056	0.007	0.007
Echinococcus multilocularis	tyrosine protein kinase Fes:Fps	0.0056	0.007	0.0084
Echinococcus granulosus	tyrosine kinase	0.0056	0.007	0.0084
Trichomonas vaginalis	AGC family protein kinase	0.0087	0.0138	0.0686
Schistosoma mansoni	family S12 unassigned peptidase (S12 family)	0.004	0.0036	0.0036
Echinococcus multilocularis	Regulator of G protein signaling 20	0.0745	0.1578	0.1885
Loa Loa (eye worm)	TK/FER protein kinase	0.0056	0.007	0.007
Brugia malayi	Protein kinase domain containing protein	0.0056	0.007	0.007
Loa Loa (eye worm)	AUR protein kinase	0.0078	0.0119	0.0119
Echinococcus multilocularis	dynamin 1	0.0068	0.0097	0.0116
Brugia malayi	Protein kinase domain containing protein	0.0056	0.007	0.007
Schistosoma mansoni	tyrosine kinase	0.0056	0.007	0.007
Schistosoma mansoni	regulator of G protein signaling 3 rgs3	0.0745	0.1578	0.1578
Trichomonas vaginalis	TKL family protein kinase	0.0056	0.007	0.0251
Trichomonas vaginalis	protein tyrosine kinase, putative	0.0056	0.007	0.0251
Brugia malayi	Calcitonin receptor-like protein seb-1	0.0049	0.0056	0.0056
Loa Loa (eye worm)	hypothetical protein	0.0029	0.0011	0.0011
Plasmodium falciparum	protein kinase, putative	0.0074	0.0111	0.8039
Trypanosoma cruzi	PH domain containing protein, putative	0.0068	0.0097	0.6027
Trichomonas vaginalis	AGC family protein kinase	0.0087	0.0138	0.0686
Leishmania major	serine/threonine-protein kinase a, putative	0.0087	0.0138	1
Brugia malayi	Protein kinase domain containing protein	0.0056	0.007	0.007
Trichomonas vaginalis	TKL family protein kinase	0.0056	0.007	0.0251
Trichomonas vaginalis	CAMK family protein kinase	0.0056	0.007	0.0251
Leishmania major	protein kinase, putative	0.0087	0.0138	1
Brugia malayi	Protein kinase domain containing protein	0.0056	0.007	0.007
Brugia malayi	Protein kinase domain containing protein	0.0298	0.06	0.06
Echinococcus multilocularis	kinase suppressor of Ras 1	0.0056	0.007	0.0084
Brugia malayi	Plexin repeat family protein	0.0874	0.1859	0.1859
Echinococcus multilocularis	tyrosine protein kinase HCK	0.0056	0.007	0.0084
Leishmania major	protein kinase, putative	0.0056	0.007	0.5114
Loa Loa (eye worm)	hypothetical protein	0.0056	0.007	0.007
Trichomonas vaginalis	AGC family protein kinase	0.0087	0.0138	0.0686
Echinococcus multilocularis	potassium voltage gated channel subfamily H	0.0041	0.0038	0.0045
Echinococcus multilocularis	tyrosine protein kinase ABL1	0.0056	0.007	0.0084
Loa Loa (eye worm)	AGC/AKT protein kinase	0.0087	0.0138	0.0138
Trichomonas vaginalis	TKL family protein kinase	0.0056	0.007	0.0251
Echinococcus granulosus	protein kinase	0.0056	0.007	0.0084
Entamoeba histolytica	hypothetical protein, conserved	0.0068	0.0097	0.0179
Loa Loa (eye worm)	TK/INSR protein kinase	0.0056	0.007	0.007
Loa Loa (eye worm)	hypothetical protein	0.0068	0.0097	0.0097
Echinococcus granulosus	ras specific guanine nucleotide releasing factor	0.0068	0.0097	0.0116
Trichomonas vaginalis	TKL family protein kinase	0.0056	0.007	0.0251
Brugia malayi	hypothetical protein	0.0029	0.0011	0.0011
Schistosoma mansoni	tyrosine kinase	0.0056	0.007	0.007
Plasmodium falciparum	serine/threonine protein kinase, putative	0.0078	0.0119	0.8643
Entamoeba histolytica	Rho guanine nucleotide exchange factor, putative	0.0068	0.0097	0.0179
Trichomonas vaginalis	Clan MA, family M8, leishmanolysin-like metallopeptidase	0.0162	0.0303	0.1756
Trypanosoma cruzi	hypothetical protein	0.0068	0.0097	0.6027
Schistosoma mansoni	tyrosine kinase	0.0056	0.007	0.007
Toxoplasma gondii	ABC1 family protein	0.004	0.0036	0.2637
Schistosoma mansoni	guanyl-nucleotide exchange factor	0.0068	0.0097	0.0097
Trichomonas vaginalis	TKL family protein kinase	0.0056	0.007	0.0251
Loa Loa (eye worm)	GTP-ase activating protein for Arf containing protein	0.0068	0.0097	0.0097
Trichomonas vaginalis	conserved hypothetical protein	0.0056	0.007	0.0251
Loa Loa (eye worm)	hypothetical protein	0.0056	0.007	0.007
Echinococcus multilocularis	FL cytokine receptor	0.0056	0.007	0.0084
Plasmodium vivax	oxysterol-binding protein/PH domain containing protein	0.0068	0.0097	0.6027
Brugia malayi	Variant SH3 domain containing protein	0.0068	0.0097	0.0097
Schistosoma mansoni	tyrosine kinase	0.0056	0.007	0.007
Trichomonas vaginalis	alpha chimerin, putative	0.0068	0.0097	0.0426
Trypanosoma cruzi	Serine/threonine-protein kinase NEK21, putative	0.0087	0.0138	1
Trichomonas vaginalis	development and differentiation-enhancing factor, ddef, putative	0.0068	0.0097	0.0426
Schistosoma mansoni	axis inhibition protein axin	0.0745	0.1578	0.1578
Echinococcus granulosus	Regulator of G protein signaling 20	0.0745	0.1578	0.1885
Plasmodium falciparum	phosphatidylinositol transfer protein, putative	0.0068	0.0097	0.7075
Trichomonas vaginalis	TKL family protein kinase	0.0056	0.007	0.0251
Entamoeba histolytica	tyrosin kinase, putative	0.0218	0.0426	0.2357
Mycobacterium ulcerans	esterase/lipase LipP	0.004	0.0036	0.5
Entamoeba histolytica	hypothetical protein	0.0162	0.0303	0.1544
Brugia malayi	Uncoordinated protein 104	0.0068	0.0097	0.0097
Trypanosoma cruzi	ADP-ribosylation factor family, putative	0.0068	0.0097	0.6027
Leishmania major	protein kinase, putative	0.0078	0.0119	0.8643
Echinococcus granulosus	tyrosine protein kinase Srms	0.0056	0.007	0.0084
Loa Loa (eye worm)	TKL/MLK/TAK1 protein kinase	0.0056	0.007	0.007
Toxoplasma gondii	phosphatidylinositol transfer protein	0.0068	0.0097	0.7075
Loa Loa (eye worm)	RGC/RGC protein kinase	0.0056	0.007	0.007
Loa Loa (eye worm)	RNA recognition domain-containing protein domain-containing protein	0.0063	0.0085	0.0085
Trichomonas vaginalis	serine/threonine-protein kinase wnk, putative	0.0056	0.007	0.0251
Echinococcus multilocularis	lamin	0.0028	0.0009	0.0011
Echinococcus multilocularis	tyrosine protein kinase Src64B	0.0056	0.007	0.0084
Plasmodium falciparum	protein kinase, putative	0.0056	0.007	0.5114
Trypanosoma brucei	serine/threonine-protein kinase NRKB, putative	0.0087	0.0138	1
Trypanosoma cruzi	Serine/threonine-protein kinase NEK17, putative	0.0087	0.0138	1
Trichomonas vaginalis	TKL family protein kinase	0.0056	0.007	0.0251
Loa Loa (eye worm)	hypothetical protein	0.0068	0.0097	0.0097
Schistosoma mansoni	tyrosine kinase	0.0056	0.007	0.007
Echinococcus multilocularis	oxysterol binding protein 1	0.0068	0.0097	0.0116
Loa Loa (eye worm)	TK/Met protein kinase	0.0056	0.007	0.007
Echinococcus granulosus	serine:threonine protein kinase 12 B	0.0078	0.0119	0.0142
Trypanosoma cruzi	hypothetical protein	0.0068	0.0097	0.6027
Brugia malayi	PH domain containing protein	0.0068	0.0097	0.0097
Onchocerca volvulus		0.0068	0.0097	0.0476
Loa Loa (eye worm)	sema domain-containing protein	0.0371	0.0759	0.0759
Brugia malayi	plexin A	0.1036	0.2214	0.2214
Echinococcus granulosus	tyrosine kinase\|tyrosine protein kinase Fyn	0.0056	0.007	0.0084
Echinococcus granulosus	regulator of G protein signaling 3	0.0745	0.1578	0.1885
Echinococcus multilocularis	plexin a4	0.1036	0.2214	0.2645
Loa Loa (eye worm)	TK/ALK protein kinase	0.0298	0.0599	0.0599
Trichomonas vaginalis	AGC family protein kinase	0.0087	0.0138	0.0686
Echinococcus granulosus	FERM and pleckstrin domain containing protein	0.0068	0.0097	0.0116
Schistosoma mansoni	tyrosine kinase	0.0056	0.007	0.007
Entamoeba histolytica	serine/threonine- protein kinase 6, putative	0.0078	0.0119	0.0322
Loa Loa (eye worm)	hypothetical protein	0.0111	0.019	0.019
Brugia malayi	hypothetical protein	0.0068	0.0097	0.0097
Trypanosoma cruzi	rac serine-threonine kinase, putative	0.0087	0.0138	1
Trichomonas vaginalis	TKL family protein kinase	0.0056	0.007	0.0251
Schistosoma mansoni	protein tyrosine kinase	0.0056	0.007	0.007
Schistosoma mansoni	tyrosine kinase	0.0056	0.007	0.007
Echinococcus multilocularis	regulator of G protein signaling 7	0.0745	0.1578	0.1885
Echinococcus granulosus	Oxysterol binding protein 11	0.0068	0.0097	0.0116
Brugia malayi	GTP-ase activating protein for Arf containing protein	0.0068	0.0097	0.0097
Echinococcus granulosus	regulator of G protein signaling 3	0.0745	0.1578	0.1885
Trichomonas vaginalis	AGC family protein kinase	0.0087	0.0138	0.0686
Schistosoma mansoni	regulator of G protein signaling 17 19 20 (rgs17 19 20)	0.0745	0.1578	0.1578
Onchocerca volvulus		0.0371	0.0759	0.4051
Toxoplasma gondii	hypothetical protein	0.0068	0.0097	0.7075
Entamoeba histolytica	serine/threonine protein kinase 6, putative	0.0078	0.0119	0.0322
Entamoeba histolytica	PH domain containing protein kinase, putative	0.0087	0.0138	0.0446
Trichomonas vaginalis	TKL family protein kinase	0.0056	0.007	0.0251
Schistosoma mansoni	lamin	0.0028	0.0009	0.0009
Schistosoma mansoni	protein kinase	0.0078	0.0119	0.0119
Echinococcus granulosus	exocyst complex component 2	0.0162	0.0303	0.0362
Schistosoma mansoni	tyrosine kinase	0.0056	0.007	0.007
Onchocerca volvulus		0.0068	0.0097	0.0476
Schistosoma mansoni	ephrin receptor	0.0061	0.0081	0.0081
Loa Loa (eye worm)	TK/FAK protein kinase	0.0056	0.007	0.007
Schistosoma mansoni	hypothetical protein	0.0371	0.0759	0.0759
Schistosoma mansoni	plexin	0.0503	0.1048	0.1048
Loa Loa (eye worm)	TK/FER protein kinase	0.0056	0.007	0.007
Schistosoma mansoni	serine/threonine protein kinase	0.3524	0.7653	0.7653
Schistosoma mansoni	hypothetical protein	0.0034	0.0022	0.0022
Entamoeba histolytica	Rho guanine nucleotide exchange factor, putative	0.0068	0.0097	0.0179
Echinococcus granulosus	intermediate filament protein	0.0028	0.0009	0.0011
Onchocerca volvulus		0.0056	0.007	0.033
Schistosoma mansoni	tyrosine kinase	0.0056	0.007	0.007
Mycobacterium leprae	DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE	0.0125	0.022	1
Loa Loa (eye worm)	AUR protein kinase	0.0078	0.0119	0.0119
Trichomonas vaginalis	TKL family protein kinase	0.0056	0.007	0.0251
Loa Loa (eye worm)	hypothetical protein	0.0068	0.0097	0.0097
Echinococcus granulosus	Immunoglobulin	0.0111	0.019	0.0227
Trichomonas vaginalis	centaurin/arf, putative	0.0068	0.0097	0.0426
Schistosoma mansoni	vesicular amine transporter	0.0113	0.0196	0.0196
Brugia malayi	SRC-1	0.0056	0.007	0.007
Trypanosoma cruzi	STE/STE11 serine/threonine-protein kinase, putative	0.0074	0.0111	0.7336
Echinococcus granulosus	fibroblast growth factor receptor 4	0.0056	0.007	0.0084
Schistosoma mansoni	serine/threonine protein kinase	0.3524	0.7653	0.7653
Loa Loa (eye worm)	hypothetical protein	0.0049	0.0056	0.0056
Trichomonas vaginalis	TKL family protein kinase	0.0056	0.007	0.0251
Trypanosoma cruzi	serine/threonine-protein kinase NRKB, putative	0.0087	0.0138	1
Echinococcus multilocularis	basic fibroblast growth factor receptor 1 A	0.0056	0.007	0.0084
Echinococcus granulosus	tyrosine protein kinase Src42A	0.0056	0.007	0.0084
Loa Loa (eye worm)	hypothetical protein	0.004	0.0036	0.0036
Echinococcus multilocularis	receptor type guanylyl cyclase	0.0056	0.007	0.0084
Trypanosoma cruzi	rac serine-threonine kinase, putative	0.0087	0.0138	1
Trichomonas vaginalis	TKL family protein kinase	0.0056	0.007	0.0251
Loa Loa (eye worm)	TK protein kinase	0.0056	0.007	0.007
Trichomonas vaginalis	TKL family protein kinase	0.0056	0.007	0.0251
Echinococcus multilocularis	exocyst complex component 2	0.0162	0.0303	0.0362
Trypanosoma cruzi	trypanothione reductase, putative	0.0049	0.0055	0.1868
Toxoplasma gondii	AtPH1 family protein	0.0068	0.0097	0.7075
Echinococcus granulosus	retinal guanylyl cyclase 2	0.0056	0.007	0.0084
Brugia malayi	PH domain containing protein	0.0068	0.0097	0.0097
Brugia malayi	PXA domain containing protein	0.0745	0.1578	0.1578
Trichomonas vaginalis	AGC family protein kinase	0.0087	0.0138	0.0686
Trichomonas vaginalis	TKL family protein kinase	0.0056	0.007	0.0251
Echinococcus multilocularis	rac serine:threonine kinase	0.0087	0.0138	0.0165
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0056	0.007	0.0084
Loa Loa (eye worm)	TK/RYK protein kinase	0.0056	0.007	0.007
Echinococcus multilocularis	pdz domain containing protein	0.0068	0.0097	0.0116
Loa Loa (eye worm)	TK/ABL protein kinase	0.0056	0.007	0.007
Echinococcus granulosus	expressed protein	0.0745	0.1578	0.1885
Trichomonas vaginalis	conserved hypothetical protein	0.0056	0.007	0.0251
Echinococcus multilocularis	expressed protein	0.0745	0.1578	0.1885
Echinococcus multilocularis	neuroglian	0.0111	0.019	0.0227
Onchocerca volvulus		0.0056	0.007	0.033
Onchocerca volvulus		0.0068	0.0097	0.0476
Brugia malayi	Plekhf2 protein	0.0068	0.0097	0.0097
Schistosoma mansoni	serine/threonine protein kinase	0.0056	0.007	0.007
Echinococcus multilocularis	calcium dependent secretion activator 1	0.0068	0.0097	0.0116
Mycobacterium tuberculosis	Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB	0.0112	0.0193	0.3284
Loa Loa (eye worm)	hypothetical protein	0.0068	0.0097	0.0097
Brugia malayi	Fibronectin type III domain containing protein	0.0116	0.0201	0.0201
Onchocerca volvulus	Tyrosine kinase receptor Cad96Ca homolog	0.0056	0.007	0.033
Loa Loa (eye worm)	hypothetical protein	0.0068	0.0097	0.0097
Trichomonas vaginalis	esterase, putative	0.004	0.0036	0.003
Loa Loa (eye worm)	beta-LACTamase domain containing family member	0.004	0.0036	0.0036
Loa Loa (eye worm)	hypothetical protein	0.004	0.0036	0.0036
Entamoeba histolytica	hypothetical protein	0.0068	0.0097	0.0179
Brugia malayi	TAR-binding protein	0.0063	0.0085	0.0085
Loa Loa (eye worm)	hypothetical protein	0.0068	0.0097	0.0097
Loa Loa (eye worm)	hypothetical protein	0.0162	0.0303	0.0303
Schistosoma mansoni	tyrosine kinase	0.0056	0.007	0.007
Echinococcus granulosus	tyrosine protein kinase ABL1	0.0056	0.007	0.0084
Loa Loa (eye worm)	GTP-ase activating protein for Arf containing protein	0.0068	0.0097	0.0097
Loa Loa (eye worm)	TK/DDR protein kinase	0.0056	0.007	0.007
Trichomonas vaginalis	TKL family protein kinase	0.0056	0.007	0.0251
Echinococcus granulosus	tyrosine protein kinase csk	0.0056	0.007	0.0084
Loa Loa (eye worm)	RGC/RGC protein kinase	0.0056	0.007	0.007
Loa Loa (eye worm)	G protein-coupled receptor kinase 1	0.3852	0.837	0.837
Loa Loa (eye worm)	hypothetical protein	0.0056	0.007	0.007
Trichomonas vaginalis	AGC family protein kinase	0.0087	0.0138	0.0686
Loa Loa (eye worm)	uncoordinated protein 104	0.0068	0.0097	0.0097
Trichomonas vaginalis	centaurin/arf, putative	0.0068	0.0097	0.0426
Brugia malayi	Variant SH3 domain containing protein	0.0068	0.0097	0.0097
Entamoeba histolytica	hypothetical protein	0.0068	0.0097	0.0179
Schistosoma mansoni	hypothetical protein	0.0534	0.1115	0.1115
Mycobacterium tuberculosis	Probable reductase	0.0112	0.0193	0.3284
Mycobacterium ulcerans	fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE	0.004	0.0036	0.5
Echinococcus granulosus	protein tyrosine kinase	0.0056	0.007	0.0084
Brugia malayi	Protein kinase domain containing protein	0.0056	0.007	0.007
Trichomonas vaginalis	AGC family protein kinase	0.0087	0.0138	0.0686
Echinococcus multilocularis	hypothetical protein	0.0371	0.0759	0.0906
Loa Loa (eye worm)	hypothetical protein	0.004	0.0036	0.0036
Echinococcus multilocularis	Pleckstrin domain containing protein, family B	0.0068	0.0097	0.0116
Schistosoma mansoni	tyrosine kinase	0.0056	0.007	0.007
Brugia malayi	glutathione reductase	0.0049	0.0055	0.0055
Brugia malayi	Protein kinase domain containing protein	0.0056	0.007	0.007
Trypanosoma brucei	STE/STE11 serine/threonine-protein kinase, putative	0.0074	0.0111	0.7336
Onchocerca volvulus		0.0056	0.007	0.033
Entamoeba histolytica	cell surface protease gp63, putative	0.0162	0.0303	0.1544
Toxoplasma gondii	thioredoxin reductase	0.0049	0.0055	0.4013
Entamoeba histolytica	protein kinase, putative	0.0087	0.0138	0.0446
Echinococcus granulosus	potassium voltage gated channel subfamily H	0.0041	0.0038	0.0045
Loa Loa (eye worm)	hypothetical protein	0.0111	0.019	0.019
Echinococcus granulosus	tyrosine kinase	0.0056	0.007	0.0084
Leishmania major	trypanothione reductase	0.0049	0.0055	0.4013
Trichomonas vaginalis	3-phosphoinositide dependent protein kinase-1, putative	0.0087	0.0138	0.0686
Loa Loa (eye worm)	TK/FER protein kinase	0.0056	0.007	0.007
Schistosoma mansoni	fibrocystin l	0.0162	0.0303	0.0303
Trichomonas vaginalis	AGC family protein kinase	0.0078	0.0119	0.0565
Schistosoma mansoni	tyrosine kinase	0.0056	0.007	0.007
Entamoeba histolytica	PH domain containing protein	0.0068	0.0097	0.0179
Echinococcus granulosus	retinal guanylyl cyclase 2	0.0056	0.007	0.0084
Echinococcus multilocularis	MAM	0.0029	0.0011	0.0013
Loa Loa (eye worm)	GTP-binding regulatory protein Gs alpha-S chain	0.01	0.0167	0.0167
Brugia malayi	Cytohesin 3	0.0068	0.0097	0.0097
Loa Loa (eye worm)	hypothetical protein	0.0056	0.007	0.007
Echinococcus multilocularis	A kinase anchor protein 10, mitochondrial	0.0745	0.1578	0.1885
Trichomonas vaginalis	serine-threonine protein kinase, putative	0.0056	0.007	0.0251
Brugia malayi	A-kinase anchor protein 10, precursor	0.0745	0.1578	0.1578
Trichomonas vaginalis	AGC family protein kinase	0.0087	0.0138	0.0686
Trypanosoma cruzi	phosphatidylinositol-4-phosphate 5-kinase, putative	0.0068	0.0097	0.6027
Brugia malayi	GTP-ase activating protein for Arf containing protein	0.0068	0.0097	0.0097
Trichomonas vaginalis	conserved hypothetical protein	0.0056	0.007	0.0251
Echinococcus multilocularis	regulator of G protein signaling 3	0.0745	0.1578	0.1885
Brugia malayi	Pleckstrin Homology Domain	0.0068	0.0097	0.0097
Echinococcus granulosus	roundabout 2	0.0116	0.0201	0.024
Leishmania major	protein kinase, putative,serine/threonine protein kinase, putative	0.0087	0.0138	1
Plasmodium vivax	conserved Plasmodium protein, unknown function	0.0068	0.0097	0.6027
Trichomonas vaginalis	TKL family protein kinase	0.0056	0.007	0.0251
Toxoplasma gondii	protein kinase domain-containing protein	0.0087	0.0138	1
Brugia malayi	protein-tyrosine kinase	0.0056	0.007	0.007
Trichomonas vaginalis	TKL family protein kinase	0.0056	0.007	0.0251
Plasmodium falciparum	acylated pleckstrin-homology domain-containing protein, putative	0.0068	0.0097	0.7075
Trichomonas vaginalis	centaurin alpha, putative	0.0068	0.0097	0.0426
Schistosoma mansoni	src-type protein tyrosine kinase-related	0.0056	0.007	0.007
Echinococcus granulosus	oxysterol binding protein 9	0.0068	0.0097	0.0116
Echinococcus granulosus	atrial natriuretic peptide receptor 1	0.0056	0.007	0.0084
Echinococcus granulosus	tyrosine protein kinase csk	0.0056	0.007	0.0084
Echinococcus granulosus	tyrosine protein kinase	0.0056	0.007	0.0084
Brugia malayi	MAX-1A	0.0068	0.0097	0.0097
Mycobacterium ulcerans	lipase LipD	0.004	0.0036	0.5
Trichomonas vaginalis	AGC family protein kinase	0.0087	0.0138	0.0686
Brugia malayi	Regulator of G protein signaling domain containing protein	0.0745	0.1578	0.1578
Echinococcus multilocularis	oxysterol binding protein 3	0.0068	0.0097	0.0116
Brugia malayi	integrin-linked kinase	0.0056	0.007	0.007
Brugia malayi	Protein kinase domain containing protein	0.0056	0.007	0.007
Echinococcus granulosus	twitchin	0.0129	0.023	0.0275
Loa Loa (eye worm)	Plekhf2 protein	0.0068	0.0097	0.0097
Brugia malayi	serine/threonine-protein kinase 6	0.0078	0.0119	0.0119
Brugia malayi	proto-oncogene tyrosine-protein kinase FER	0.0056	0.007	0.007
Trypanosoma cruzi	aurora B kinase, putative	0.0078	0.0119	0.8157
Loa Loa (eye worm)	serine/threonine protein kinase	0.0056	0.007	0.007
Schistosoma mansoni	serine/threonine protein kinase	0.0056	0.007	0.007
Loa Loa (eye worm)	hypothetical protein	0.0068	0.0097	0.0097
Loa Loa (eye worm)	hypothetical protein	0.0068	0.0097	0.0097
Echinococcus multilocularis	collagen type iv alpha 3 binding protein	0.0068	0.0097	0.0116
Trichomonas vaginalis	TKL family protein kinase	0.0056	0.007	0.0251
Echinococcus granulosus	tyrosine protein kinase shark	0.0056	0.007	0.0084
Echinococcus multilocularis	tar DNA binding protein	0.0063	0.0085	0.0101
Loa Loa (eye worm)	hypothetical protein	0.0056	0.007	0.007
Trichomonas vaginalis	TKL family protein kinase	0.0056	0.007	0.0251
Brugia malayi	Intermediate filament tail domain containing protein	0.0028	0.0009	0.0009
Echinococcus multilocularis	serine:threonine protein kinase 12 B	0.0078	0.0119	0.0142
Loa Loa (eye worm)	hypothetical protein	0.0056	0.007	0.007
Onchocerca volvulus		0.004	0.0036	0.0146
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0056	0.007	0.007
Brugia malayi	hypothetical protein	0.0745	0.1578	0.1578
Schistosoma mansoni	Neurotrimin precursor (hNT)	0.0111	0.019	0.019
Entamoeba histolytica	PH domain containing protein	0.0068	0.0097	0.0179
Mycobacterium tuberculosis	Possible penicillin-binding protein	0.0258	0.0513	1
Entamoeba histolytica	protein kinase, putative	0.0078	0.0119	0.0322
Loa Loa (eye worm)	hypothetical protein	0.0029	0.0011	0.0011
Toxoplasma gondii	hypothetical protein	0.0068	0.0097	0.7075
Brugia malayi	Dynamin	0.0068	0.0097	0.0097
Loa Loa (eye worm)	hypothetical protein	0.0068	0.0097	0.0097
Echinococcus granulosus	Arf GAP and Pleckstrin domain containing protein	0.0068	0.0097	0.0116
Brugia malayi	Protein kinase domain containing protein	0.0056	0.007	0.007
Echinococcus granulosus	c src tyrosine kinase	0.0056	0.007	0.0084
Plasmodium falciparum	oxysterol-binding protein, putative	0.0068	0.0097	0.7075
Loa Loa (eye worm)	TK/FER protein kinase	0.0056	0.007	0.007
Echinococcus granulosus	Pleckstrin y	0.0068	0.0097	0.0116
Schistosoma mansoni	tyrosine-protein kinase fps85d	0.0056	0.007	0.007
Echinococcus multilocularis	thioredoxin glutathione reductase	0.0049	0.0055	0.0066
Brugia malayi	Protein kinase domain containing protein	0.0087	0.0138	0.0138
Loa Loa (eye worm)	TKL/RAF/RAF protein kinase	0.0056	0.007	0.007
Onchocerca volvulus		0.0056	0.007	0.033
Trichomonas vaginalis	kinesin light chain, putative	0.0068	0.0097	0.0426
Trichomonas vaginalis	conserved hypothetical protein	0.0162	0.0303	0.1756
Onchocerca volvulus		0.0056	0.007	0.033

Activities

Activity type	Activity value	Assay description	Source	Reference
CC50 (functional)	= 200 uM	Cytotoxicity in C8166 cell lines	ChEMBL.	No reference
CC50 (functional)	= 200 uM	Concentration required to reduce cell viability of JM cells by 50%	ChEMBL.	No reference
CC50 (functional)	= 200 uM	Concentration required to reduce cell viability of MT2 cells by 50%	ChEMBL.	No reference
EC50 (functional)	= 10 uM	Anti-HIV activity against HIV-1 infected C8166 cell lines	ChEMBL.	No reference
EC50 (functional)	= 10 uM	Anti-HIV activity against HIV-1 infected JM cell lines	ChEMBL.	No reference
EC50 (functional)	= 10 uM	Anti-HIV activity against HIV-2 infected MT2 cell lines	ChEMBL.	No reference
EC50 (functional)	= 20 uM	Anti-HIV activity against HIV-1 infected C8166 cell lines	ChEMBL.	No reference
EC50 (functional)	= 20 uM	Anti-HIV activity against HIV-1 infected JM cell lines	ChEMBL.	No reference
EC50 (functional)	= 20 uM	Anti-HIV activity against HIV-2 infected MT2 cell lines	ChEMBL.	No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: 227890

Bibliographic References

No literature references available for this target.

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Detailed information for compound 130680