Detailed information for compound 1382161

Basic information

Technical information
  • TDR Targets ID: 1382161
  • Name: N-[2-[(2-methylphenyl)amino]-2-oxoethyl]-4-(t rifluoromethyl)benzamide
  • MW: 336.308 | Formula: C17H15F3N2O2
  • H donors: 2 H acceptors: 2 LogP: 3.35 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(Nc1ccccc1C)CNC(=O)c1ccc(cc1)C(F)(F)F
  • InChi: 1S/C17H15F3N2O2/c1-11-4-2-3-5-14(11)22-15(23)10-21-16(24)12-6-8-13(9-7-12)17(18,19)20/h2-9H,10H2,1H3,(H,21,24)(H,22,23)
  • InChiKey: FWFSENABSQWOCU-UHFFFAOYSA-N  

Network

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Synonyms

  • N-[2-[(2-methylphenyl)amino]-2-oxo-ethyl]-4-(trifluoromethyl)benzamide
  • N-[2-keto-2-[(2-methylphenyl)amino]ethyl]-4-(trifluoromethyl)benzamide
  • SMR000253888
  • ZINC03344493
  • T5318396
  • MLS000336334

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens ATPase family, AAA domain containing 5 Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core Get druggable targets OG5_139225 All targets in OG5_139225

By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Trypanosoma cruzi cdc2-related kinase 1 0.0527 0.0279 0.0312
Brugia malayi Protein kinase domain containing protein 0.0277 0.0027 0.0011
Schistosoma mansoni serine/threonine protein kinase 0.0431 0.0182 0.0394
Brugia malayi hypothetical protein 0.0687 0.0439 0.0473
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0438 0.0189 0.1662
Trichomonas vaginalis AGC family protein kinase 0.067 0.0422 0.3546
Schistosoma mansoni serine/threonine protein kinase 0.251 0.2269 0.5381
Trichomonas vaginalis conserved hypothetical protein 0.0277 0.0027 0.0226
Entamoeba histolytica protein kinase domain containing protein 0.1382 0.1137 1
Echinococcus multilocularis tyrosine kinase 0.0277 0.0027 0.0027
Brugia malayi Protein kinase domain containing protein 0.0372 0.0123 0.0119
Loa Loa (eye worm) TK/FER protein kinase 0.0277 0.0027 0.0011
Entamoeba histolytica PH domain containing protein kinase, putative 0.0866 0.0618 0.544
Plasmodium vivax tyrosine kinase-like protein, putative 0.0277 0.0027 0.0092
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.1633 0.1389 0.154
Trichomonas vaginalis TKL family protein kinase 0.0277 0.0027 0.0226
Echinococcus multilocularis mitogen activated protein kinase 14 0.914 0.8926 0.8926
Entamoeba histolytica protein kinase , putative 0.0693 0.0445 0.3916
Brugia malayi protein kinase C II. 0.0795 0.0548 0.0595
Loa Loa (eye worm) hypothetical protein 0.0644 0.0396 0.0425
Loa Loa (eye worm) hypothetical protein 0.1076 0.0829 0.0911
Loa Loa (eye worm) hypothetical protein 0.0379 0.013 0.0126
Loa Loa (eye worm) hypothetical protein 0.0379 0.013 0.0126
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.033 0.008 0.0597
Brugia malayi Protein kinase domain containing protein 0.5609 0.5381 0.6021
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.1183 0.0937 0.105
Giardia lamblia Kinase, NEK 0.0277 0.0027 0.0226
Brugia malayi RhoGAP domain containing protein 0.0419 0.017 0.0172
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.1382 0.1137 0.1274
Loa Loa (eye worm) hypothetical protein 0.0439 0.0189 0.0193
Loa Loa (eye worm) TK/CSK protein kinase 0.0277 0.0027 0.0011
Trichomonas vaginalis TKL family protein kinase 0.0277 0.0027 0.0226
Schistosoma mansoni nck2/grb4 0.0439 0.0189 0.0412
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.062 0.0372 0.0398
Brugia malayi Protein kinase domain containing protein 0.195 0.1707 0.1896
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.1203 0.0957 0.8908
Loa Loa (eye worm) hypothetical protein 0.1673 0.1429 0.1585
Brugia malayi ephrin receptor 1 precursor 0.031 0.006 0.0049
Echinococcus multilocularis tyrosine kinase 0.0522 0.0273 0.0273
Schistosoma mansoni neuroglian 0.0342 0.0092 0.0179
Echinococcus granulosus casein kinase I alpha 0.0701 0.0453 0.0489
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0277 0.0027 0.0237
Entamoeba histolytica protein kinase, putative 0.0612 0.0364 0.3199
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0821 0.0574 0.0625
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.2592 0.2352 0.262
Schistosoma mansoni protein kinase 0.0277 0.0027 0.0023
Trichomonas vaginalis TKL family protein kinase 0.0277 0.0027 0.0226
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.0381 0.0132 0.0148
Brugia malayi integrin-linked kinase 0.0277 0.0027 0.0011
Entamoeba histolytica tyrosine kinase, putative 0.0277 0.0027 0.0237
Echinococcus granulosus tyrosine protein kinase ABL1 0.2612 0.2372 0.2643
Brugia malayi Protein kinase domain containing protein 0.1203 0.0957 0.1055
Schistosoma mansoni serine/threonine protein kinase 0.1804 0.1561 0.3688
Echinococcus multilocularis mitogen activated protein kinase 11 0.914 0.8926 0.8926
Loa Loa (eye worm) hypothetical protein 0.0277 0.0027 0.0011
Schistosoma mansoni kinase 0.0423 0.0174 0.0374
Onchocerca volvulus 0.049 0.0241 0.0279
Echinococcus multilocularis expressed conserved protein 0.0305 0.0056 0.0056
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.1192 0.0946 0.1043
Echinococcus granulosus kinase suppressor of Ras 1 0.0277 0.0027 0.0011
Echinococcus granulosus activated cdc42 kinase 1 0.195 0.1707 0.1896
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0381 0.0132 0.0129
Entamoeba histolytica protein kinase, putative 0.0277 0.0027 0.0237
Echinococcus granulosus growth factor receptor bound protein 2 0.0457 0.0208 0.0214
Brugia malayi Protein kinase domain containing protein 0.0277 0.0027 0.0011
Brugia malayi casein kinase 1, delta 0.0701 0.0453 0.0489
Loa Loa (eye worm) hypothetical protein 0.0772 0.0525 0.057
Brugia malayi STE20-like kinase MST 0.0441 0.0192 0.0196
Schistosoma mansoni serine/threonine protein kinase 0.0373 0.0124 0.0254
Schistosoma mansoni protein kinase 0.0402 0.0153 0.0324
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0693 0.0445 0.0445
Brugia malayi Protein kinase domain containing protein 0.0379 0.0129 0.0126
Entamoeba histolytica hypothetical protein 0.0279 0.003 0.026
Entamoeba histolytica serine/threonine kinase, putative 0.0277 0.0027 0.0237
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0426 0.0177 0.0177
Trichomonas vaginalis TKL family protein kinase 0.0277 0.0027 0.0226
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.616 0.5934 0.6642
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0772 0.0525 0.0588
Trypanosoma brucei mitogen-activated protein kinase kinase 5 0.1435 0.119 0.1333
Schistosoma mansoni serine/threonine protein kinase 0.0693 0.0445 0.1023
Schistosoma mansoni tyrosine kinase 0.1608 0.1364 0.3217
Schistosoma mansoni tyrosine kinase 0.0277 0.0027 0.0023
Echinococcus granulosus tyrosine kinase 0.1012 0.0766 0.084
Loa Loa (eye worm) hypothetical protein 0.0712 0.0464 0.0501
Trichomonas vaginalis CK1 family protein kinase 0.0701 0.0453 0.3806
Entamoeba histolytica tyrosin kinase, putative 0.0277 0.0027 0.0237
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0527 0.0279 0.0294
Schistosoma mansoni serine/threonine protein kinase 0.0527 0.0279 0.0625
Entamoeba histolytica protein kinase, putative 0.0277 0.0027 0.0237
Entamoeba histolytica protein kinase, putative 0.0277 0.0027 0.0237
Entamoeba histolytica cell division protein kinase 2, putative 0.0571 0.0323 0.284
Echinococcus granulosus tyrosine kinase 0.0277 0.0027 0.0011
Trichomonas vaginalis CAMK family protein kinase 0.0381 0.0132 0.1109
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0277 0.0027 0.0023
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0701 0.0453 0.0507
Schistosoma mansoni cell adhesion molecule 0.0342 0.0092 0.0179
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.0277 0.0027 0.0011
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.0381 0.0132 0.0148
Echinococcus granulosus atrial natriuretic peptide receptor 1 0.0277 0.0027 0.0011
Schistosoma mansoni tyrosine kinase 0.0976 0.073 0.1702
Trichomonas vaginalis TKL family protein kinase 0.0277 0.0027 0.0226
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0419 0.017 0.0172
Entamoeba histolytica protein kinase domain containing protein 0.1317 0.1072 0.9429
Trypanosoma cruzi mitogen-activated protein kinase kinase 5 0.1435 0.119 0.1333
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0431 0.0182 0.0185
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0277 0.0027 0.0011
Echinococcus multilocularis epidermal growth factor receptor 0.0976 0.073 0.073
Brugia malayi Egg laying defective protein 4 0.0305 0.0056 0.0043
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0612 0.0364 0.3285
Trichomonas vaginalis TKL family protein kinase 0.0277 0.0027 0.0226
Giardia lamblia Kinase, CK1 Casein kinase 0.0701 0.0453 0.3806
Loa Loa (eye worm) TK protein kinase 0.0277 0.0027 0.0011
Schistosoma mansoni tyrosine kinase 0.0277 0.0027 0.0023
Schistosoma mansoni serine/threonine protein kinase 0.1382 0.1137 0.2675
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0277 0.0027 0.0023
Loa Loa (eye worm) SRC-1 0.1205 0.096 0.1058
Schistosoma mansoni hypothetical protein 0.0772 0.0525 0.1213
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0351 0.0101 0.0101
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0277 0.0027 0.0092
Schistosoma mansoni vesicular amine transporter 0.0712 0.0464 0.1067
Schistosoma mansoni serine/threonine kinase 0.062 0.0372 0.0847
Brugia malayi Protein kinase domain containing protein 0.0653 0.0405 0.0436
Echinococcus multilocularis neuroglian 0.0342 0.0092 0.0092
Trichomonas vaginalis AGC family protein kinase 0.0277 0.0027 0.0226
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0277 0.0027 0.0011
Brugia malayi proto-oncogene tyrosine-protein kinase FER 0.0277 0.0027 0.0011
Giardia lamblia Kinase, CMGC CK2 0.0267 0.0017 0.0145
Schistosoma mansoni tyrosine kinase 0.0715 0.0467 0.1075
Onchocerca volvulus 0.0923 0.0676 0.0844
Echinococcus multilocularis insulin receptor 0.1542 0.1297 0.1297
Schistosoma mansoni serine/threonine protein kinase 0.0612 0.0364 0.0828
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.1082 0.0835 0.0918
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0816 0.0568 0.0568
Trichomonas vaginalis conserved hypothetical protein 0.0277 0.0027 0.0226
Echinococcus multilocularis activated cdc42 kinase 1 0.195 0.1707 0.1707
Entamoeba histolytica ankyrin repeat protein 0.0277 0.0027 0.0237
Entamoeba histolytica protein kinase domain containing protein 0.0277 0.0027 0.0237
Brugia malayi Protein kinase domain containing protein 0.0464 0.0215 0.0222
Entamoeba histolytica protein kinase domain containing protein 0.0277 0.0027 0.0237
Echinococcus granulosus activated cdc42 kinase 1 0.195 0.1707 0.1896
Trichomonas vaginalis serine-threonine protein kinase, putative 0.0277 0.0027 0.0226
Giardia lamblia Kinase, AGC PKA 0.033 0.008 0.0674
Leishmania major protein kinase, putative 0.0469 0.022 0.0247
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0307 0.0057 0.0095
Entamoeba histolytica cysteine surface protein, putative 0.0277 0.0027 0.0237
Loa Loa (eye worm) CAMK protein kinase 0.0431 0.0182 0.0185
Brugia malayi Immunoglobulin I-set domain containing protein 0.0307 0.0057 0.0045
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.294 0.2701 0.2701
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.062 0.0372 0.0398
Echinococcus granulosus casein kinase i 0.0701 0.0453 0.0489
Plasmodium falciparum cGMP-dependent protein kinase 0.0305 0.0056 0.0364
Schistosoma mansoni serine/threonine protein kinase 0.0553 0.0304 0.0685
Entamoeba histolytica protein kinase domain containing protein 0.0277 0.0027 0.0237
Trichomonas vaginalis TKL family protein kinase 0.0277 0.0027 0.0226
Giardia lamblia Kinase, CMGC GSK 0.1317 0.1072 0.901
Trichomonas vaginalis CMGC family protein kinase 0.031 0.006 0.0508
Echinococcus granulosus raf serine:threonine protein kinase 0.045 0.0201 0.0207
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0815 0.0567 0.0617
Trichomonas vaginalis protein kinase atn1, putative 0.0277 0.0027 0.0226
Schistosoma mansoni serine/threonine protein kinase 0.0381 0.0132 0.0274
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.2458 0.2217 0.247
Echinococcus granulosus casein kinase I delta 0.0701 0.0453 0.0489
Giardia lamblia Aurora kinase 0.0693 0.0445 0.3742
Loa Loa (eye worm) hypothetical protein 0.0612 0.0364 0.0389
Schistosoma mansoni protein kinase 0.2592 0.2352 0.5578
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0469 0.022 0.0247
Trichomonas vaginalis CAMK family protein kinase 0.0351 0.0101 0.0851
Schistosoma mansoni serine/threonine protein kinase 0.0381 0.0132 0.0274
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0351 0.0101 0.0094
Entamoeba histolytica protein kinase, putative 0.0693 0.0445 0.3916
Schistosoma mansoni serine/threonine protein kinase 0.0679 0.0431 0.0989
Schistosoma mansoni protein kinase 0.0277 0.0027 0.0023
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.1561 0.1316 0.1316
Onchocerca volvulus 0.2864 0.2625 0.3375
Echinococcus granulosus slit 2 protein 0.0291 0.0042 0.0028
Entamoeba histolytica serine/threonine kinase, putative 0.0277 0.0027 0.0237
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0428 0.0178 0.15
Schistosoma mansoni serine/threonine protein kinase 0.0839 0.0592 0.1373
Onchocerca volvulus 0.0683 0.0435 0.053
Entamoeba histolytica protein kinase domain containing protein 0.0277 0.0027 0.0237
Brugia malayi Protein kinase domain containing protein 0.0277 0.0027 0.0011
Trichomonas vaginalis TKL family protein kinase 0.0277 0.0027 0.0226
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0379 0.0129 0.0126
Schistosoma mansoni rap gtpase-activating protein 0.0772 0.0525 0.1213
Entamoeba histolytica protein kinase, putative 0.0277 0.0027 0.0237
Trichomonas vaginalis STE family protein kinase 0.0426 0.0177 0.1488
Echinococcus multilocularis cyclin dependent kinase 5 0.0527 0.0279 0.0279
Trichomonas vaginalis CAMK family protein kinase 0.0284 0.0034 0.0285
Loa Loa (eye worm) TK/FER protein kinase 0.0522 0.0273 0.0288
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.914 0.8926 1
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0426 0.0177 0.0179
Trypanosoma brucei rac serine-threonine kinase, putative 0.0807 0.056 0.0627
Entamoeba histolytica hypothetical protein 0.0277 0.0027 0.0237
Entamoeba histolytica protein kinase, putative 0.0277 0.0027 0.0237
Loa Loa (eye worm) serine/threonine protein kinase 0.0277 0.0027 0.0011
Loa Loa (eye worm) TK/FER protein kinase 0.0522 0.0273 0.0288
Onchocerca volvulus 0.0508 0.026 0.0302
Echinococcus multilocularis protein kinase c iota type 0.0886 0.0638 0.0638
Loa Loa (eye worm) protein kinase domain-containing protein 0.0392 0.0143 0.0141
Loa Loa (eye worm) hypothetical protein 0.0295 0.0046 0.0032
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0979 0.0732 0.0732
Trichomonas vaginalis CK1 family protein kinase 0.0701 0.0453 0.3806
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0381 0.0132 0.0132
Echinococcus granulosus protein kinase c iota type 0.0886 0.0638 0.0697
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.062 0.0372 0.0398
Trichomonas vaginalis CMGC family protein kinase 0.0527 0.0279 0.2343
Trichomonas vaginalis CAMK family protein kinase 0.0284 0.0034 0.0285
Trichomonas vaginalis TK family protein kinase 0.0277 0.0027 0.0226
Trichomonas vaginalis CAMK family protein kinase 0.0351 0.0101 0.0851
Schistosoma mansoni ephrin receptor 0.0348 0.0098 0.0193
Loa Loa (eye worm) RGC/RGC protein kinase 0.0277 0.0027 0.0011
Entamoeba histolytica hypothetical protein 0.0277 0.0027 0.0237
Echinococcus multilocularis casein kinase ii subunit alpha 0.0267 0.0017 0.0017
Trichomonas vaginalis AGC family protein kinase 0.0307 0.0057 0.0482
Echinococcus granulosus tyrosine protein kinase Srms 0.0974 0.0727 0.0797
Schistosoma mansoni src-type protein tyrosine kinase-related 0.0277 0.0027 0.0023
Onchocerca volvulus 0.0701 0.0453 0.0553
Echinococcus granulosus tyrosine protein kinase Src42A 0.1205 0.096 0.1058
Loa Loa (eye worm) TK/FER protein kinase 0.0522 0.0273 0.0288
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0426 0.0177 0.0179
Echinococcus multilocularis titin 0.0431 0.0182 0.0182
Echinococcus granulosus c src tyrosine kinase 0.0715 0.0467 0.0505
Brugia malayi serine/threonine kinase 12 0.0693 0.0445 0.048
Echinococcus granulosus Immunoglobulin 0.0712 0.0464 0.0501
Plasmodium falciparum calcium-dependent protein kinase 4 0.0612 0.0364 0.3285
Trichomonas vaginalis CAMK family protein kinase 0.0381 0.0132 0.1109
Schistosoma mansoni protein kinase 0.0426 0.0177 0.0382
Brugia malayi Protein kinase domain containing protein 0.1542 0.1297 0.1437
Echinococcus multilocularis dual specificity 0.031 0.006 0.006
Entamoeba histolytica tyrosine kinase, putative 0.0277 0.0027 0.0237
Entamoeba histolytica tyrosin kinase, putative 0.0329 0.0079 0.0698
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0816 0.0568 0.0619
Entamoeba histolytica tyrosine kinase, putative 0.0277 0.0027 0.0237
Trichomonas vaginalis TKL family protein kinase 0.0277 0.0027 0.0226
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0295 0.0045 0.0045
Loa Loa (eye worm) hypothetical protein 0.0307 0.0057 0.0045
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0612 0.0364 0.0389
Echinococcus multilocularis tyrosine protein kinase ABL1 0.2612 0.2372 0.2372
Loa Loa (eye worm) hypothetical protein 0.0307 0.0057 0.0045
Trichomonas vaginalis TKL family protein kinase 0.0277 0.0027 0.0226
Echinococcus granulosus protein tyrosine kinase 0.4435 0.4203 0.4698
Entamoeba histolytica tyrosine kinase, putative 0.0277 0.0027 0.0237
Schistosoma mansoni tyrosine kinase 0.0277 0.0027 0.0023
Entamoeba histolytica hypothetical protein 0.1382 0.1137 1
Onchocerca volvulus 0.1019 0.0772 0.0968
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0816 0.0568 0.0568
Trichomonas vaginalis TKL family protein kinase 0.0277 0.0027 0.0226
Schistosoma mansoni serine/threonine protein kinase 0.0706 0.0458 0.1054
Entamoeba histolytica protein kinase, putative 0.0807 0.056 0.4922
Schistosoma mansoni serine/threonine protein kinase 0.0337 0.0087 0.0167
Entamoeba histolytica protein kinase, putative 0.1382 0.1137 1
Brugia malayi Protein kinase domain containing protein 0.0277 0.0027 0.0011
Trichomonas vaginalis AGC family protein kinase 0.029 0.0041 0.034
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0277 0.0027 0.0237
Echinococcus granulosus retinal guanylyl cyclase 2 0.0277 0.0027 0.0011
Echinococcus multilocularis kinase suppressor of Ras 1 0.0277 0.0027 0.0027
Entamoeba histolytica tyrosine kinase, putative 0.0277 0.0027 0.0237
Brugia malayi Protein kinase domain containing protein 0.037 0.012 0.0116
Schistosoma mansoni tyrosine kinase 0.0277 0.0027 0.0023
Leishmania major protein kinase, putative 0.1203 0.0957 0.1072
Echinococcus multilocularis cyclin dependent kinase 9 0.0486 0.0238 0.0238
Entamoeba histolytica protein kinase domain containing protein 0.0277 0.0027 0.0237
Echinococcus multilocularis NCK adaptor protein 0.0457 0.0208 0.0208
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0469 0.022 0.1924
Entamoeba histolytica tyrosine kinase, putative 0.0277 0.0027 0.0237
Trypanosoma cruzi rac serine-threonine kinase, putative 0.038 0.013 0.0146
Schistosoma mansoni protein kinase 0.0277 0.0027 0.0023
Brugia malayi P38 map kinase family protein 2 0.914 0.8926 1
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0612 0.0364 0.3285
Schistosoma mansoni serine/threonine protein kinase 0.062 0.0372 0.0847
Trichomonas vaginalis TKL family protein kinase 0.0277 0.0027 0.0226
Loa Loa (eye worm) hypothetical protein 0.0747 0.0499 0.0541
Trichomonas vaginalis TKL family protein kinase 0.0277 0.0027 0.0226
Echinococcus granulosus activin receptor type 0.458 0.4348 0.4861
Trypanosoma cruzi casein kinase, putative 0.0701 0.0453 0.0507
Onchocerca volvulus 0.0522 0.0273 0.032
Echinococcus granulosus serine:threonine protein kinase TAO1 0.294 0.2701 0.3013
Echinococcus granulosus TGF beta receptor type 1 0.0997 0.0751 0.0823
Brugia malayi SRC-1 0.1205 0.096 0.1058
Schistosoma mansoni tyrosine kinase 0.1542 0.1297 0.3059
Schistosoma mansoni tyrosine kinase 0.1205 0.096 0.2252
Loa Loa (eye worm) CAMK/PIM protein kinase 0.251 0.2269 0.2528
Schistosoma mansoni serine/threonine-protein kinase 0.038 0.013 0.027
Echinococcus granulosus Protein kinase C brain isozyme 0.0839 0.0592 0.0645
Loa Loa (eye worm) TK protein kinase 0.0277 0.0027 0.0011
Loa Loa (eye worm) TK/FER protein kinase 0.0522 0.0273 0.0288
Loa Loa (eye worm) hypothetical protein 0.0845 0.0597 0.0651
Trichomonas vaginalis CMGC family protein kinase 0.0267 0.0017 0.0145
Brugia malayi Immunoglobulin I-set domain containing protein 0.0495 0.0247 0.0257
Brugia malayi Immunoglobulin I-set domain containing protein 0.1812 0.1569 0.1741
Echinococcus granulosus ephrin type A receptor 4 A 0.0348 0.0098 0.0091
Schistosoma mansoni protein kinase 0.1836 0.1593 0.3765
Schistosoma mansoni serine/threonine protein kinase 0.0396 0.0147 0.0311
Echinococcus multilocularis roundabout 2 0.0342 0.0092 0.0092
Trichomonas vaginalis CMGC family protein kinase 0.0527 0.0279 0.2343
Loa Loa (eye worm) TK/FER protein kinase 0.0859 0.0611 0.0667
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0426 0.0177 0.0177
Entamoeba histolytica tyrosine kinase, putative 0.0277 0.0027 0.0237
Loa Loa (eye worm) hypothetical protein 0.0712 0.0464 0.0501
Brugia malayi Protein kinase domain containing protein 0.0277 0.0027 0.0011
Echinococcus granulosus tyrosine protein kinase 0.0277 0.0027 0.0011
Giardia lamblia Kinase, CMGC GSK 0.1317 0.1072 0.901
Schistosoma mansoni cell adhesion molecule 0.0342 0.0092 0.0179
Echinococcus granulosus [G-protein-coupledreceptor] kinase 0.1489 0.1245 0.1378
Plasmodium falciparum protein serine/threonine kinase-1 0.1203 0.0957 0.8908
Echinococcus multilocularis beta adrenergic receptor kinase 0.0337 0.0087 0.0087
Trypanosoma brucei polo-like protein kinase 0.0351 0.0101 0.0113
Loa Loa (eye worm) TK/FER protein kinase 0.0522 0.0273 0.0288
Onchocerca volvulus Serine\/threonine kinase homolog 0.0351 0.0101 0.0097
Echinococcus granulosus c-Jun N-terminal kinases 0.3291 0.3053 0.3408
Plasmodium vivax protein kinase, putative 0.0293 0.0044 0.0251
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.0772 0.0525 0.057
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0307 0.0057 0.038
Trichomonas vaginalis CAMK family protein kinase 0.0381 0.0132 0.1109
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0277 0.0027 0.0023
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.1205 0.096 0.096
Loa Loa (eye worm) hypothetical protein 0.0372 0.0123 0.0119
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0277 0.0027 0.0237
Leishmania major mitogen-activated protein kinase kinase 5, putative;with=GeneDB:LmxM36.0860 0.1435 0.119 0.1333
Onchocerca volvulus 0.0772 0.0525 0.0647
Schistosoma mansoni serine/threonine protein kinase 0.0351 0.0101 0.0201
Brugia malayi protein kinase C3,putative 0.0458 0.0209 0.0215
Toxoplasma gondii protein kinase domain-containing protein 0.0277 0.0027 0.0092
Loa Loa (eye worm) TK/INSR protein kinase 0.1542 0.1297 0.1437
Trichomonas vaginalis CMGC family protein kinase 0.1203 0.0957 0.8042
Echinococcus granulosus tyrosine protein kinase Fyn 0.1205 0.096 0.1058
Trichomonas vaginalis STE family protein kinase 0.0277 0.0027 0.0226
Schistosoma mansoni protein kinase 0.0469 0.022 0.0485
Giardia lamblia Kinase, NEK 0.0307 0.0057 0.0482
Trichomonas vaginalis AGC family protein kinase 0.0807 0.056 0.4703
Entamoeba histolytica protein kinase, putative 0.0277 0.0027 0.0237
Loa Loa (eye worm) AGC/PKG protein kinase 0.0305 0.0056 0.0043
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0816 0.0568 0.0619
Echinococcus multilocularis protein kinase c epsilon type 0.0795 0.0548 0.0548
Entamoeba histolytica protein kinase, putative 0.0693 0.0445 0.3916
Echinococcus granulosus cGMP dependent protein kinase 0.0305 0.0056 0.0043
Schistosoma mansoni vav2 0.0469 0.022 0.0485
Schistosoma mansoni tyrosine kinase 0.0277 0.0027 0.0023
Trichomonas vaginalis TKL family protein kinase 0.0277 0.0027 0.0226
Brugia malayi Immunoglobulin I-set domain containing protein 0.0307 0.0057 0.0045
Entamoeba histolytica hypothetical protein, conserved 0.0277 0.0027 0.0237
Entamoeba histolytica protein kinase domain containing protein 0.0277 0.0027 0.0237
Echinococcus granulosus defective proboscis extension response 0.0712 0.0464 0.0501
Loa Loa (eye worm) thyroid receptor interactor 0.0918 0.0671 0.0734
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0342 0.0092 0.0084
Echinococcus granulosus serine:threonine protein kinase 0.0372 0.0123 0.0119
Brugia malayi Protein kinase domain containing protein 0.251 0.2269 0.2528
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.1382 0.1137 0.1274
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.251 0.2269 0.2269
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0772 0.0525 0.0588
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0277 0.0027 0.0237
Entamoeba histolytica receptor protein kinase, putative 0.0277 0.0027 0.0237
Plasmodium vivax protein kinase Crk2 0.0527 0.0279 0.248
Schistosoma mansoni tyrosine kinase 0.1542 0.1297 0.3059
Brugia malayi Fes/CIP4 homology domain containing protein 0.0918 0.0671 0.0734
Trichomonas vaginalis CAMK family protein kinase 0.0381 0.0132 0.1109
Brugia malayi SH2 domain containing protein 0.0522 0.0273 0.0288
Brugia malayi ribosomal protein S6 kinase alpha 3 0.1133 0.0887 0.0976
Echinococcus granulosus mitogen activated protein kinase 11 0.914 0.8926 1
Echinococcus granulosus dual specificity mitogen activated protein 0.1435 0.119 0.1316
Trypanosoma brucei SNF1-related protein kinases, putative 0.0381 0.0132 0.0148
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0342 0.0092 0.0084
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0816 0.0568 0.0637
Loa Loa (eye worm) TKL/STKR/TYPE2 protein kinase 0.0879 0.0632 0.069
Entamoeba histolytica hypothetical protein 0.0277 0.0027 0.0237
Echinococcus granulosus contactin 0.0342 0.0092 0.0084
Entamoeba histolytica protein kinase, putative 0.0438 0.0189 0.1662
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.0593 0.0345 0.0345
Trichomonas vaginalis STE family protein kinase 0.0426 0.0177 0.1488
Brugia malayi Protein kinase domain containing protein 0.062 0.0372 0.0398
Brugia malayi Tyrosine-protein kinase abl-1 0.1291 0.1045 0.1154
Loa Loa (eye worm) CMGC/CDK/CDK9 protein kinase 0.0443 0.0194 0.0198
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.1205 0.096 0.1058
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0816 0.0568 0.0637
Trichomonas vaginalis CMGC family protein kinase 0.1317 0.1072 0.901
Echinococcus granulosus cyclin dependent kinase 1 0.0527 0.0279 0.0294
Entamoeba histolytica protein kinase, putative 0.0277 0.0027 0.0237
Brugia malayi Homeodomain interacting protein kinase protein 1 0.0381 0.0131 0.0128
Echinococcus multilocularis heat shock protein 70 0.0277 0.0027 0.0027
Schistosoma mansoni titin 0.0307 0.0057 0.0095
Schistosoma mansoni serine/threonine protein kinase 0.0527 0.0279 0.0625
Echinococcus multilocularis hemicentin 1 0.0307 0.0057 0.0057
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.1027 0.078 0.078
Trichomonas vaginalis AGC family protein kinase 0.0807 0.056 0.4703
Echinococcus multilocularis epidermal growth factor receptor 0.113 0.0884 0.0884
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0317 0.0067 0.0067
Schistosoma mansoni protein kinase 0.037 0.012 0.0247
Entamoeba histolytica tyrosine kinase, putative 0.0277 0.0027 0.0237
Schistosoma mansoni protein kinase 0.0469 0.022 0.0485
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0795 0.0548 0.0595
Brugia malayi casein kinase I 0.0701 0.0453 0.0489
Loa Loa (eye worm) TK/ABL protein kinase 0.2612 0.2372 0.2643
Loa Loa (eye worm) TK protein kinase 0.0767 0.0519 0.0564
Schistosoma mansoni kinase 0.0443 0.0194 0.0421
Onchocerca volvulus 0.1069 0.0822 0.1033
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0816 0.0568 0.0637
Entamoeba histolytica protein kinase, putative 0.1382 0.1137 1
Echinococcus granulosus titin 0.0431 0.0182 0.0185
Trichomonas vaginalis TKL family protein kinase 0.0277 0.0027 0.0226
Echinococcus granulosus mitogen activated protein kinase 14 0.914 0.8926 1
Echinococcus granulosus Vam6:Vps39 protein 0.0772 0.0525 0.057
Brugia malayi Protein kinase domain containing protein 0.0522 0.0273 0.0288
Brugia malayi Protein kinase domain containing protein 0.0821 0.0574 0.0625
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0527 0.0279 0.248
Trichomonas vaginalis STE family protein kinase 0.0426 0.0177 0.1488
Entamoeba histolytica hypothetical protein 0.0277 0.0027 0.0237
Echinococcus granulosus serine:threonine protein kinase N2 0.1301 0.1056 0.1166
Echinococcus multilocularis activin receptor type 0.458 0.4348 0.4348
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0342 0.0092 0.0092
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0965 0.0718 0.0718
Schistosoma mansoni serine/threonine-protein kinase 0.038 0.013 0.027
Entamoeba histolytica PH domain containing protein kinase, putative 0.038 0.013 0.1146
Schistosoma mansoni tyrosine kinase 0.0277 0.0027 0.0023
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.033 0.008 0.0597
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.1577 0.1333 0.1333
Echinococcus granulosus tyrosine protein kinase csk 0.0277 0.0027 0.0011
Echinococcus multilocularis Immunoglobulin 0.0712 0.0464 0.0464
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.1203 0.0957 0.1072
Echinococcus granulosus insulin growth factor 1 receptor beta 0.1577 0.1333 0.1476
Schistosoma mansoni tyrosine kinase 0.0976 0.073 0.1702
Trichomonas vaginalis CMGC family protein kinase 0.031 0.006 0.0508
Entamoeba histolytica tyrosine kinase, putative 0.0277 0.0027 0.0237
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.1027 0.078 0.0856
Entamoeba histolytica p21-activated kinase 0.0476 0.0227 0.1998
Schistosoma mansoni growth factor receptor-bound protein 0.0457 0.0208 0.0456
Trichomonas vaginalis CMGC family protein kinase 0.0267 0.0017 0.0145
Brugia malayi serine/threonine-protein kinase 6 0.0693 0.0445 0.048
Entamoeba histolytica protein kinase domain containing protein 0.0277 0.0027 0.0237
Brugia malayi Protein kinase domain containing protein 0.0277 0.0027 0.0011
Echinococcus multilocularis 0.101 0.0764 0.0764
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0277 0.0027 0.0011
Echinococcus granulosus maternal embryonic leucine zipper kinase 0.0284 0.0034 0.0019
Giardia lamblia Kinase, CAMK CAMKL 0.0425 0.0176 0.1479
Trypanosoma cruzi rac serine-threonine kinase, putative 0.033 0.008 0.009
Schistosoma mansoni serine/threonine protein kinase 0.0816 0.0568 0.1317
Plasmodium vivax calcium-dependent protein kinase, putative 0.0612 0.0364 0.3285
Loa Loa (eye worm) CMGC/GSK protein kinase 0.1317 0.1072 0.1184
Schistosoma mansoni serine/threonine kinase 0.0508 0.0259 0.0578
Loa Loa (eye worm) hypothetical protein 0.0715 0.0467 0.0505
Entamoeba histolytica protein kinase domain containing protein 0.0277 0.0027 0.0237
Schistosoma mansoni protein kinase 0.1082 0.0835 0.1954
Entamoeba histolytica protein kinase, putative 0.0613 0.0365 0.3212
Trichomonas vaginalis AGC family protein kinase 0.0693 0.0445 0.3742
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.914 0.8926 1
Schistosoma mansoni tyrosine kinase 0.0921 0.0674 0.1568
Trypanosoma brucei cdc2-related kinase 3 0.0527 0.0279 0.0312
Echinococcus granulosus cGMP dependent protein kinase 1 0.0305 0.0056 0.0043
Loa Loa (eye worm) hypothetical protein 0.0277 0.0027 0.0011
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0816 0.0568 0.0619
Schistosoma mansoni serine/threonine protein kinase 0.0373 0.0124 0.0254
Brugia malayi Protein kinase domain containing protein 0.0277 0.0027 0.0011
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0277 0.0027 0.0023
Loa Loa (eye worm) hypothetical protein 0.0352 0.0103 0.0096
Echinococcus granulosus dual specificity 0.1382 0.1137 0.1257
Onchocerca volvulus 0.0522 0.0273 0.032
Leishmania major protein kinase, putative 0.0693 0.0445 0.0499
Loa Loa (eye worm) TKL/LRRK protein kinase 0.0521 0.0273 0.0287
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0277 0.0027 0.0027
Echinococcus multilocularis G protein coupled receptor kinase 6 0.1489 0.1245 0.1245
Brugia malayi Immunoglobulin I-set domain containing protein 0.0307 0.0057 0.0045
Trichomonas vaginalis CAMK family protein kinase 0.0381 0.0132 0.1109
Loa Loa (eye worm) hypothetical protein 0.4952 0.4721 0.528
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0481 0.0232 0.0232
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0612 0.0364 0.0389
Loa Loa (eye worm) hypothetical protein 0.0277 0.0027 0.0011
Trichomonas vaginalis CAMK family protein kinase 0.0381 0.0132 0.1109
Schistosoma mansoni hypothetical protein 0.0277 0.0027 0.0023
Trypanosoma brucei aurora B kinase 0.0693 0.0445 0.0499
Brugia malayi Protein kinase domain containing protein 0.0277 0.0027 0.0011
Echinococcus multilocularis macrophage colony stimulating factor 1 receptor 0.0277 0.0027 0.0027
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0816 0.0568 0.5225
Schistosoma mansoni serine/threonine protein kinase 0.0337 0.0087 0.0167
Echinococcus multilocularis homeodomain interacting protein kinase 3 0.0381 0.0131 0.0131
Echinococcus multilocularis maternal embryonic leucine zipper kinase 0.0284 0.0034 0.0034
Trichomonas vaginalis AGC family protein kinase 0.0693 0.0445 0.3742
Entamoeba histolytica tyrosin kinase, putative 0.0277 0.0027 0.0237
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.062 0.0372 0.0372
Schistosoma mansoni serine/threonine protein kinase 0.1203 0.0957 0.2245
Trichomonas vaginalis CMGC family protein kinase 0.031 0.006 0.0508
Entamoeba histolytica serine/threonine protein kinase, putative 0.0381 0.0132 0.116
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.1489 0.1245 0.1378
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0701 0.0453 0.0489
Schistosoma mansoni adapter molecule crk 0.0439 0.0189 0.0412
Trichomonas vaginalis CMGC family protein kinase 0.0527 0.0279 0.2343
Loa Loa (eye worm) gastrulation defective protein 1 0.1612 0.1367 0.1516
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0381 0.0132 0.0148
Echinococcus granulosus tyrosine protein kinase Src64B 0.1205 0.096 0.1058
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.294 0.2701 0.3013
Trichomonas vaginalis conserved hypothetical protein 0.0277 0.0027 0.0226
Echinococcus multilocularis protein kinase 0.0277 0.0027 0.0027
Echinococcus multilocularis tyrosine protein kinase Fyn 0.1012 0.0766 0.0766
Entamoeba histolytica hypothetical protein 0.0277 0.0027 0.0237
Trichomonas vaginalis TKL family protein kinase 0.0277 0.0027 0.0226
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0612 0.0364 0.0389
Trichomonas vaginalis TKL family protein kinase 0.0277 0.0027 0.0226
Echinococcus multilocularis dual specificity protein kinase clk2 0.1203 0.0957 0.0957
Schistosoma mansoni tyrosine kinase 0.0513 0.0265 0.0591
Schistosoma mansoni serine/threonine RGC 0.0277 0.0027 0.0023
Trichomonas vaginalis TKL family protein kinase 0.0277 0.0027 0.0226
Brugia malayi Immunoglobulin I-set domain containing protein 0.0342 0.0092 0.0084
Echinococcus multilocularis cyclin dependent kinase 7 0.0706 0.0458 0.0458
Trypanosoma cruzi protein kinase, putative 0.0277 0.0027 0.003
Loa Loa (eye worm) AUR protein kinase 0.0693 0.0445 0.048
Echinococcus granulosus roundabout 2 0.0342 0.0092 0.0084
Plasmodium falciparum protein kinase 5 0.0527 0.0279 0.248
Brugia malayi Protein kinase domain containing protein 0.0498 0.0249 0.0261
Giardia lamblia Kinase, NEK 0.0307 0.0057 0.0482
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0307 0.0057 0.038
Trichomonas vaginalis AGC family protein kinase 0.0807 0.056 0.4703
Brugia malayi Protein kinase domain containing protein 0.0277 0.0027 0.0011
Trichomonas vaginalis TKL family protein kinase 0.0277 0.0027 0.0226
Echinococcus granulosus cyclin dependent kinase 0.0527 0.0279 0.0294
Entamoeba histolytica tyrosine- protein kinase 2, putative 0.0277 0.0027 0.0237
Echinococcus multilocularis c Jun NH2 terminal kinase 0.3291 0.3053 0.3053
Echinococcus multilocularis twitchin 0.0396 0.0147 0.0147
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0553 0.0304 0.0322
Trichomonas vaginalis TKL family protein kinase 0.0277 0.0027 0.0226
Echinococcus granulosus NCK adaptor protein 0.0439 0.0189 0.0193
Entamoeba histolytica casein kinase, putative 0.0267 0.0017 0.0151
Trichomonas vaginalis TKL family protein kinase 0.0279 0.003 0.0249
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0816 0.0568 0.0619
Loa Loa (eye worm) hypothetical protein 0.0747 0.0499 0.0541
Brugia malayi Immunoglobulin I-set domain containing protein 0.0342 0.0092 0.0084
Toxoplasma gondii AGC kinase 0.0816 0.0568 0.5225
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0612 0.0364 0.3285
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0712 0.0464 0.1067
Brugia malayi Guanylyl cyclase protein 23 0.0277 0.0027 0.0011
Brugia malayi Protein kinase domain containing protein 0.0522 0.0273 0.0288
Brugia malayi Protein kinase domain containing protein 0.0277 0.0027 0.0011
Leishmania major protein kinase A catalytic subunit isoform 1 0.0816 0.0568 0.0637
Leishmania major protein kinase, putative 0.0612 0.0364 0.0407
Trypanosoma brucei Flagellum attachment zone protein 20 0.0277 0.0027 0.003
Onchocerca volvulus 0.0385 0.0136 0.0142
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.1561 0.1316 0.1458
Schistosoma mansoni tyrosine kinase 0.0277 0.0027 0.0023
Schistosoma mansoni serine/threonine protein kinase 0.031 0.006 0.0103
Brugia malayi Protein kinase domain containing protein 0.0522 0.0273 0.0288
Trichomonas vaginalis CAMK family protein kinase 0.0372 0.0123 0.1032
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.0464 0.0215 0.0222
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0701 0.0453 0.0489
Schistosoma mansoni serine/threonine protein kinase 0.1027 0.078 0.1822
Echinococcus multilocularis TGF beta receptor type 1 0.0997 0.0751 0.0751
Echinococcus granulosus N chimaerin 0.0419 0.017 0.0172
Echinococcus multilocularis tyrosine protein kinase otk 0.0307 0.0057 0.0057
Echinococcus granulosus tyrosine protein kinase Btk29A 0.265 0.241 0.2686
Brugia malayi p70 ribosomal S6 kinase beta 0.0757 0.0509 0.0552
Schistosoma mansoni roundabout 0.0307 0.0057 0.0095
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0921 0.0674 0.0737
Schistosoma mansoni tyrosine kinase 0.0277 0.0027 0.0023
Echinococcus granulosus cyclin dependent kinase 9 0.0486 0.0238 0.0247
Brugia malayi Protein kinase domain 0.0426 0.0177 0.0179
Trichomonas vaginalis TKL family protein kinase 0.0277 0.0027 0.0226
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0277 0.0027 0.0011
Echinococcus multilocularis roundabout 2 0.1053 0.0807 0.0807
Brugia malayi hypothetical protein 0.0747 0.0499 0.0541
Trichomonas vaginalis STE family protein kinase 0.0402 0.0153 0.1285
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.1205 0.096 0.096
Brugia malayi Variant SH3 domain containing protein 0.0439 0.0189 0.0193
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0277 0.0027 0.0092
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0277 0.0027 0.0023
Loa Loa (eye worm) CMGC/GSK protein kinase 0.1317 0.1072 0.1184
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0839 0.0592 0.0592
Entamoeba histolytica hypothetical protein 0.0277 0.0027 0.0237
Onchocerca volvulus 0.0431 0.0182 0.0202
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0351 0.0101 0.0113
Trichomonas vaginalis AGC family protein kinase 0.0664 0.0416 0.3494
Loa Loa (eye worm) CAMK/PKD protein kinase 0.1211 0.0965 0.1064
Loa Loa (eye worm) hypothetical protein 0.0845 0.0597 0.0651
Schistosoma mansoni protein kinase 0.0701 0.0453 0.1041
Echinococcus multilocularis tyrosine protein kinase 0.0277 0.0027 0.0027
Echinococcus multilocularis tyrosine protein kinase csk 0.0277 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.119 0.0944 0.104
Entamoeba histolytica protein kinase domain containing protein 0.0267 0.0017 0.0151
Echinococcus multilocularis raf serine:threonine protein kinase 0.045 0.0201 0.0201
Giardia lamblia Kinase, CMGC CDK 0.0527 0.0279 0.2343
Echinococcus multilocularis growth factor receptor bound protein 2 0.0439 0.0189 0.0189
Echinococcus multilocularis rac serine:threonine kinase 0.038 0.013 0.013
Echinococcus granulosus roundabout 2 0.0342 0.0092 0.0084
Echinococcus multilocularis mitogen activated protein kinase 11 0.914 0.8926 0.8926
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0277 0.0027 0.0011
Loa Loa (eye worm) hypothetical protein 0.101 0.0764 0.0838
Schistosoma mansoni serine/threonine protein kinase 0.1203 0.0957 0.2245
Entamoeba histolytica protein kinase domain containing protein 0.0329 0.0079 0.0698
Brugia malayi Protein kinase domain containing protein 0.0821 0.0574 0.0625
Loa Loa (eye worm) TK/FAK protein kinase 0.4485 0.4252 0.4754
Entamoeba histolytica protein kinase, putative 0.0277 0.0027 0.0237
Echinococcus multilocularis natriuretic peptide receptor 1 0.0277 0.0027 0.0027
Echinococcus granulosus tyrosine protein kinase Lyn 0.1398 0.1153 0.1275
Loa Loa (eye worm) hypothetical protein 0.0277 0.0027 0.0011
Loa Loa (eye worm) hypothetical protein 0.0638 0.039 0.0418
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0772 0.0525 0.0588
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0772 0.0525 0.1213
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.0441 0.0192 0.0196
Plasmodium falciparum protein kinase, putative 0.0469 0.022 0.1924
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0612 0.0364 0.0389
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0277 0.0027 0.0226
Brugia malayi serine/threonine-protein kinase PAK 7 0.2458 0.2217 0.247
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.062 0.0372 0.0372
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0612 0.0364 0.0364
Loa Loa (eye worm) hypothetical protein 0.0815 0.0567 0.0617
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.0295 0.0045 0.0031
Loa Loa (eye worm) hypothetical protein 0.0816 0.0568 0.0619
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0419 0.017 0.017
Schistosoma mansoni tyrosine kinase 0.0277 0.0027 0.0023
Entamoeba histolytica cell division protein kinase 2, putative 0.0527 0.0279 0.2452
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0277 0.0027 0.0027
Entamoeba histolytica protein kinase, putative 0.062 0.0372 0.327
Trichomonas vaginalis TKL family protein kinase 0.0277 0.0027 0.0226
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0976 0.073 0.08
Trichomonas vaginalis TKL family protein kinase 0.0277 0.0027 0.0226
Brugia malayi Protein kinase domain containing protein 0.0277 0.0027 0.0011
Schistosoma mansoni serine/threonine protein kinase 0.0706 0.0458 0.1054
Entamoeba histolytica protein kinase, putative 0.028 0.003 0.0266
Brugia malayi Immunoglobulin I-set domain containing protein 0.0307 0.0057 0.0045
Echinococcus granulosus serine:threonine kinase SAD 1 0.0381 0.0132 0.0129
Onchocerca volvulus 0.0522 0.0273 0.032
Echinococcus granulosus tyrosine protein kinase pr2 0.0277 0.0027 0.0011
Loa Loa (eye worm) RGC/RGC protein kinase 0.0277 0.0027 0.0011
Echinococcus multilocularis protein tyrosine kinase 0.4435 0.4203 0.4203
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.2701 0.2461 0.2743
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.1717 0.1474 0.1635
Brugia malayi Raf kinase 0.0277 0.0027 0.0011
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0612 0.0364 0.0389
Schistosoma mansoni protein tyrosine kinase 0.0277 0.0027 0.0023
Trichomonas vaginalis TKL family protein kinase 0.0277 0.0027 0.0226
Schistosoma mansoni protein kinase 0.0997 0.0751 0.1752
Loa Loa (eye worm) TK/FER protein kinase 0.0277 0.0027 0.0011
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0693 0.0445 0.3916
Entamoeba histolytica protein kinase with ankyrin repeats, putative 0.0277 0.0027 0.0237
Echinococcus multilocularis protein KINase family member (kin 25) 0.0921 0.0674 0.0674
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0351 0.0101 0.0094
Trypanosoma cruzi casein kinase, putative 0.0701 0.0453 0.0507
Trichomonas vaginalis CAMK family protein kinase 0.0464 0.0215 0.1808
Schistosoma mansoni serine/threonine protein kinase 0.1561 0.1316 0.3104
Trichomonas vaginalis TKL family protein kinase 0.0277 0.0027 0.0226
Trichomonas vaginalis STE family protein kinase 0.0426 0.0177 0.1488
Loa Loa (eye worm) AGC/PKA protein kinase 0.0816 0.0568 0.0619
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0277 0.0027 0.0237
Brugia malayi map kinase activated protein kinase protein 2 0.0593 0.0345 0.0368
Loa Loa (eye worm) RGC/RGC protein kinase 0.0277 0.0027 0.0011
Trichomonas vaginalis AGC family protein kinase 0.0807 0.056 0.4703
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0553 0.0304 0.0322
Schistosoma mansoni protein kinase 0.0277 0.0027 0.0023
Trichomonas vaginalis AGC family protein kinase 0.0816 0.0568 0.4777
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0965 0.0718 0.0787
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.031 0.006 0.0068
Schistosoma mansoni tyrosine kinase 0.0759 0.0511 0.118
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0612 0.0364 0.0364
Echinococcus multilocularis N chimaerin 0.0419 0.017 0.017
Trichomonas vaginalis br serine/threonine-protein kinase, putative 0.0277 0.0027 0.0226
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0277 0.0027 0.0237
Loa Loa (eye worm) hypothetical protein 0.1069 0.0822 0.0903
Loa Loa (eye worm) TK/FER protein kinase 0.0277 0.0027 0.0011
Trichomonas vaginalis STE family protein kinase 0.0307 0.0057 0.0482
Brugia malayi hypothetical protein 0.0522 0.0273 0.0288
Plasmodium vivax casein kinase 1, putative 0.0701 0.0453 0.413
Plasmodium falciparum tyrosine kinase-like protein 0.0277 0.0027 0.0092
Echinococcus granulosus retinal guanylyl cyclase 2 0.0277 0.0027 0.0011
Entamoeba histolytica protein kinase domain containing protein 0.0277 0.0027 0.0237
Schistosoma mansoni protein kinase 0.0693 0.0445 0.1023
Echinococcus multilocularis receptor type guanylyl cyclase 0.0277 0.0027 0.0027
Brugia malayi hypothetical protein 0.0277 0.0027 0.0011
Entamoeba histolytica PH domain containing protein kinase, putative 0.0866 0.0618 0.544
Schistosoma mansoni cell adhesion molecule 0.0849 0.0602 0.1397
Toxoplasma gondii protein kinase 0.0277 0.0027 0.0092
Entamoeba histolytica tyrosine kinase, putative 0.0277 0.0027 0.0237
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0527 0.0279 0.0312
Onchocerca volvulus 0.0522 0.0273 0.032
Entamoeba histolytica protein kinase domain containing protein 0.0277 0.0027 0.0237
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0277 0.0027 0.0237
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.1205 0.096 0.1058
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0381 0.0132 0.0148
Entamoeba histolytica tyrosine kinase, putative 0.0277 0.0027 0.0237
Plasmodium vivax glycogen synthase kinase 3, putative 0.1317 0.1072 1
Echinococcus multilocularis FL cytokine receptor 0.0277 0.0027 0.0027
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0317 0.0067 0.0056
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0817 0.0569 0.062
Trichomonas vaginalis TKL family protein kinase 0.0277 0.0027 0.0226
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0612 0.0364 0.0364
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.1012 0.0766 0.084
Brugia malayi hypothetical protein 0.0277 0.0027 0.0011
Echinococcus multilocularis serine:threonine protein kinase 38 0.062 0.0372 0.0372
Trichomonas vaginalis CAMK family protein kinase 0.0277 0.0027 0.0226
Echinococcus granulosus integrin linked protein kinase 0.0277 0.0027 0.0011
Onchocerca volvulus Slit protein homolog 0.0291 0.0042 0.0019
Schistosoma mansoni serine/threonine protein kinase 0.045 0.0201 0.044
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0469 0.022 0.0228
Loa Loa (eye worm) hypothetical protein 0.0291 0.0042 0.0028
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0469 0.022 0.022
Echinococcus granulosus titin 0.0431 0.0182 0.0185
Trichomonas vaginalis TKL family protein kinase 0.0277 0.0027 0.0226
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.1064 0.0817 0.0898
Loa Loa (eye worm) hypothetical protein 0.0687 0.0439 0.0473
Brugia malayi Protein kinase domain containing protein 0.4485 0.4252 0.4754
Giardia lamblia Kinase, AGC AKT 0.1133 0.0887 0.7455
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0527 0.0279 0.0294
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.1317 0.1072 0.1072
Trypanosoma brucei cdc2-related kinase 1 0.0527 0.0279 0.0312
Loa Loa (eye worm) hypothetical protein 0.031 0.0061 0.0049
Brugia malayi Protein kinase domain containing protein 0.0277 0.0027 0.0011
Loa Loa (eye worm) camk/dcamkl protein kinase 0.0323 0.0074 0.0063
Entamoeba histolytica hypothetical protein 0.0422 0.0172 0.1517
Echinococcus granulosus epidermal growth factor receptor 0.0976 0.073 0.08
Entamoeba histolytica tyrosine kinase, putative 0.0277 0.0027 0.0237
Echinococcus multilocularis hemicentin 1 0.0307 0.0057 0.0057
Leishmania major hypothetical protein, conserved 0.0277 0.0027 0.003
Trichomonas vaginalis STE family protein kinase 0.1435 0.119 1
Schistosoma mansoni serine/threonine protein kinase 0.062 0.0372 0.0847
Loa Loa (eye worm) TK protein kinase 0.0277 0.0027 0.0011
Plasmodium falciparum calcium-dependent protein kinase 3 0.0612 0.0364 0.3285
Brugia malayi Serine/threonine-protein kinase Pim-3 0.251 0.2269 0.2528
Trichomonas vaginalis TKL family protein kinase 0.0277 0.0027 0.0226
Echinococcus granulosus serine threonine protein kinase nrc 0.033 0.008 0.0071
Leishmania major protein kinase, putative 0.1203 0.0957 0.1072
Echinococcus granulosus tyrosine protein kinase Fyn 0.1205 0.096 0.1058
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0715 0.0467 0.1075
Loa Loa (eye worm) TK/FER protein kinase 0.0522 0.0273 0.0288
Brugia malayi Protein kinase domain containing protein 0.0879 0.0632 0.069
Entamoeba histolytica serine/threonine kinase, putative 0.0277 0.0027 0.0237
Loa Loa (eye worm) hypothetical protein 0.0277 0.0027 0.0011
Loa Loa (eye worm) hypothetical protein 0.0277 0.0027 0.0011
Echinococcus granulosus lachesin 0.0307 0.0057 0.0045
Entamoeba histolytica protein kinase domain containing protein 0.1317 0.1072 0.9429
Plasmodium falciparum calcium-dependent protein kinase 1 0.0612 0.0364 0.3285
Echinococcus granulosus tyrosine kinase 0.0522 0.0273 0.0288
Brugia malayi Hr1 repeat family protein 0.1921 0.1678 0.1864
Entamoeba histolytica protein kinase, putative 0.0277 0.0027 0.0237
Onchocerca volvulus 0.0414 0.0165 0.0179
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0612 0.0364 0.3285
Brugia malayi Cam kinase protein 1 0.0612 0.0364 0.0389
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0816 0.0568 0.5225
Echinococcus granulosus phosphorylase kinase gamma subunit 0.0338 0.0088 0.008
Loa Loa (eye worm) hypothetical protein 0.0307 0.0057 0.0045
Echinococcus granulosus fibroblast growth factor receptor 4 0.1608 0.1364 0.1511
Leishmania major casein kinase, putative 0.0701 0.0453 0.0507
Trypanosoma cruzi casein kinase, putative 0.0701 0.0453 0.0507
Schistosoma mansoni serine/threonine protein kinase 0.0305 0.0056 0.0092
Schistosoma mansoni cell adhesion molecule 0.0307 0.0057 0.0095
Entamoeba histolytica serine/threonine kinase, putative 0.0277 0.0027 0.0237
Echinococcus granulosus rho-associated protein kinase 1 0.0683 0.0435 0.0469
Toxoplasma gondii STE kinase 0.0277 0.0027 0.0092
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0426 0.0177 0.0179
Echinococcus granulosus serine:threonine protein kinase N2 0.1921 0.1678 0.1864
Plasmodium falciparum protein kinase, putative 0.0277 0.0027 0.0092
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0522 0.0273 0.2405
Entamoeba histolytica protein kinase, putative 0.0277 0.0027 0.0237
Echinococcus multilocularis neuroglian 0.0916 0.0669 0.0669
Brugia malayi bone morphogenetic protein type 1 receptor 0.1082 0.0835 0.0918
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.2249 0.2007 0.2233
Schistosoma mansoni serine/threonine protein kinase 0.0277 0.0027 0.0023
Loa Loa (eye worm) hypothetical protein 0.0821 0.0574 0.0625
Brugia malayi Protein kinase domain containing protein 0.0522 0.0273 0.0288
Brugia malayi cell division control protein 2 homolog 0.0527 0.0279 0.0294
Entamoeba histolytica serine/threonine kinase, putative 0.0277 0.0027 0.0237
Giardia lamblia Kinase, STE STE20 0.0426 0.0177 0.1488
Loa Loa (eye worm) TK/RYK protein kinase 0.0277 0.0027 0.0011
Entamoeba histolytica protein kinase, putative 0.0277 0.0027 0.0237
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0469 0.022 0.0247
Giardia lamblia Kinase, STE STE20 0.1435 0.119 1
Loa Loa (eye worm) TK/ACK protein kinase 0.0277 0.0027 0.0011
Trichomonas vaginalis AGC family protein kinase 0.0693 0.0445 0.3742
Entamoeba histolytica tyrosine kinase, putative 0.0277 0.0027 0.0237
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.1317 0.1072 0.1201
Loa Loa (eye worm) hypothetical protein 0.0342 0.0092 0.0084
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.0372 0.0123 0.0119
Entamoeba histolytica tyrosin kinase, putative 0.0277 0.0027 0.0237
Trichomonas vaginalis CAMK family protein kinase 0.0351 0.0101 0.0851
Trichomonas vaginalis TKL family protein kinase 0.0277 0.0027 0.0226
Trichomonas vaginalis TKL family protein kinase 0.0277 0.0027 0.0226
Trichomonas vaginalis TKL family protein kinase 0.0277 0.0027 0.0226
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.1203 0.0957 0.1072
Trichomonas vaginalis TKL family protein kinase 0.0277 0.0027 0.0226
Loa Loa (eye worm) AUR protein kinase 0.0693 0.0445 0.048
Loa Loa (eye worm) CAMK/PIM protein kinase 0.251 0.2269 0.2528
Entamoeba histolytica protein kinase domain containing protein 0.0277 0.0027 0.0237
Echinococcus multilocularis mitogen activated protein kinase 14 0.914 0.8926 0.8926
Echinococcus multilocularis Immunoglobulin 0.0712 0.0464 0.0464
Brugia malayi protein C17H12.11 0.0687 0.0439 0.0473
Brugia malayi cyclin-dependent kinase 7 homolog 0.075 0.0502 0.0545
Echinococcus multilocularis tyrosine protein kinase csk 0.0277 0.0027 0.0027
Brugia malayi hypothetical protein 0.294 0.2701 0.3013
Trichomonas vaginalis TKL family protein kinase 0.0277 0.0027 0.0226
Plasmodium falciparum NIMA related kinase 1 0.0307 0.0057 0.038
Loa Loa (eye worm) hypothetical protein 0.0923 0.0676 0.074
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.1203 0.0957 0.1072
Leishmania major protein kinase, putative 0.0277 0.0027 0.003
Loa Loa (eye worm) AGC/PKN protein kinase 0.1921 0.1678 0.1864
Trichomonas vaginalis TKL family protein kinase 0.0277 0.0027 0.0226
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.251 0.2269 0.2528
Trichomonas vaginalis CMGC family protein kinase 0.1317 0.1072 0.901
Brugia malayi Protein kinase domain containing protein 0.1717 0.1474 0.1635
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.265 0.241 0.241
Entamoeba histolytica tyrosine kinase, putative 0.0277 0.0027 0.0237
Schistosoma mansoni serine/threonine protein kinase 0.0381 0.0131 0.0273
Trichomonas vaginalis CAMK family protein kinase 0.0381 0.0132 0.1109
Loa Loa (eye worm) TK/EPH protein kinase 0.0367 0.0118 0.0113
Echinococcus multilocularis tyrosine protein kinase pr2 0.0277 0.0027 0.0027
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0508 0.026 0.0291
Loa Loa (eye worm) TK protein kinase 0.0277 0.0027 0.0011
Onchocerca volvulus 0.0288 0.0038 0.0015
Brugia malayi C1-like domain containing protein 0.1211 0.0965 0.1064
Schistosoma mansoni serine/threonine protein kinase 0.0379 0.0129 0.0268
Onchocerca volvulus 0.0379 0.013 0.0134
Loa Loa (eye worm) TK/KIN6 protein kinase 0.0277 0.0027 0.0011
Loa Loa (eye worm) hypothetical protein 0.0772 0.0525 0.057
Schistosoma mansoni serine/threonine protein kinase 0.0381 0.0132 0.0274
Brugia malayi Protein kinase domain containing protein 0.0363 0.0114 0.0108
Echinococcus granulosus receptor type guanylyl cyclase 0.0277 0.0027 0.0011
Echinococcus multilocularis serine:threonine protein kinase N2 0.1921 0.1678 0.1678
Trichomonas vaginalis conserved hypothetical protein 0.0277 0.0027 0.0226
Loa Loa (eye worm) hypothetical protein 0.195 0.1707 0.1896
Echinococcus granulosus MAP kinase activated protein kinase 2 0.0593 0.0345 0.0368
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0693 0.0445 0.3916
Trichomonas vaginalis TKL family protein kinase 0.0277 0.0027 0.0226
Entamoeba histolytica hypothetical protein 0.028 0.003 0.0266
Trichomonas vaginalis TKL family protein kinase 0.0277 0.0027 0.0226
Brugia malayi Protein kinase domain containing protein 0.0277 0.0027 0.0011
Schistosoma mansoni tyrosine kinase 0.07 0.0452 0.1039
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0772 0.0525 0.1213
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0277 0.0027 0.0011
Brugia malayi Protein kinase domain containing protein 0.1382 0.1137 0.1257
Trichomonas vaginalis TKL family protein kinase 0.0277 0.0027 0.0226
Loa Loa (eye worm) hypothetical protein 0.0747 0.0499 0.0541
Loa Loa (eye worm) hypothetical protein 0.0747 0.0499 0.0541
Trichomonas vaginalis CAMK family protein kinase 0.0351 0.0101 0.0851
Schistosoma mansoni serine/threonine protein kinase 0.0305 0.0056 0.0092
Trypanosoma cruzi cdc2-related kinase 3 0.0527 0.0279 0.0312
Entamoeba histolytica protein kinase domain containing protein 0.0277 0.0027 0.0237
Schistosoma mansoni serine/threonine protein kinase 0.0338 0.0088 0.017
Trichomonas vaginalis TKL family protein kinase 0.0277 0.0027 0.0226
Schistosoma mansoni serine/threonine protein kinase 0.1921 0.1678 0.3968
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.2592 0.2352 0.2352
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.1203 0.0957 0.1072
Echinococcus granulosus retinal guanylyl cyclase 2 0.0277 0.0027 0.0011
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0859 0.0611 0.0611
Trichomonas vaginalis TKL family protein kinase 0.0277 0.0027 0.0226
Echinococcus multilocularis serine threonine protein kinase 0.0665 0.0417 0.0417
Entamoeba histolytica hypothetical protein 0.028 0.003 0.0266
Echinococcus granulosus hemicentin 1 0.0307 0.0057 0.0045
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.033 0.008 0.008
Loa Loa (eye worm) TK/FER protein kinase 0.0277 0.0027 0.0011
Brugia malayi Protein kinase domain containing protein 0.0521 0.0273 0.0287
Entamoeba histolytica protein kinase domain containing protein 0.0277 0.0027 0.0237
Echinococcus multilocularis 0.1064 0.0817 0.0817
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0307 0.0057 0.0045
Echinococcus granulosus casein kinase I alpha 0.0701 0.0453 0.0489
Plasmodium falciparum tyrosine kinase-like protein 0.0277 0.0027 0.0092
Echinococcus granulosus dual specificity 0.031 0.006 0.0049
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.1211 0.0965 0.1064
Echinococcus granulosus calcium activated potassium channel 0.0373 0.0124 0.0119
Brugia malayi Stress-activated protein kinase jnk-1 0.3291 0.3053 0.3408
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0879 0.0632 0.069
Trichomonas vaginalis TKL family protein kinase 0.0277 0.0027 0.0226
Trichomonas vaginalis CAMK family protein kinase 0.0381 0.0132 0.1109
Trichomonas vaginalis CMGC family protein kinase 0.031 0.006 0.0508
Schistosoma mansoni tyrosine kinase 0.0277 0.0027 0.0023
Giardia lamblia Kinase, CAMK CAMKL 0.0425 0.0176 0.1479
Giardia lamblia Kinase, CMGC CLK 0.1203 0.0957 0.8042
Brugia malayi Protein kinase domain containing protein 0.0807 0.056 0.0609
Schistosoma mansoni serine/threonine protein kinase 0.1633 0.1389 0.3278
Schistosoma mansoni tyrosine kinase 0.113 0.0884 0.2071
Echinococcus granulosus tyrosine protein kinase otk 0.0307 0.0057 0.0045
Brugia malayi Variant SH3 domain containing protein 0.0297 0.0047 0.0034
Brugia malayi Sex muscle abnormal protein 5 0.0439 0.0189 0.0193
Brugia malayi Peroxidasin 0.031 0.0061 0.0049
Echinococcus multilocularis 0.0256 0.0006 0.0006
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.1203 0.0957 0.1072
Echinococcus multilocularis serine:threonine protein kinase receptor R3 0.0997 0.0751 0.0751
Entamoeba histolytica hypothetical protein 0.028 0.003 0.0266
Brugia malayi Protein kinase domain containing protein 0.0277 0.0027 0.0011
Plasmodium falciparum protein kinase, putative 0.0277 0.0027 0.0092
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.031 0.006 0.0049
Echinococcus multilocularis tyrosine protein kinase Fyn 0.1205 0.096 0.096
Echinococcus granulosus cyclin dependent kinase 19 0.1804 0.1561 0.1732
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0277 0.0027 0.0027
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0553 0.0304 0.0304
Schistosoma mansoni protein kinase 0.2592 0.2352 0.5578
Echinococcus granulosus 3'partial|retinal guanylyl cyclase 2 0.0277 0.0027 0.0011
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0277 0.0027 0.0027
Schistosoma mansoni septate junction protein 0.0307 0.0057 0.0095
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0816 0.0568 0.0637
Brugia malayi serine/threonine protein kinase 6 0.0693 0.0445 0.048
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.031 0.006 0.0049
Schistosoma mansoni protein kinase 0.0277 0.0027 0.0023
Trichomonas vaginalis TKL family protein kinase 0.0277 0.0027 0.0226
Entamoeba histolytica protein kinase domain containing protein 0.0277 0.0027 0.0237
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0342 0.0092 0.0179
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0305 0.0056 0.0364
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.031 0.006 0.0068
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0297 0.0047 0.0034
Schistosoma mansoni protein kinase C mu 0.1211 0.0965 0.2265
Schistosoma mansoni nephrin 0.0951 0.0704 0.164
Echinococcus multilocularis tyrosine protein kinase Fyn 0.1205 0.096 0.096
Entamoeba histolytica protein kinase, putative 0.0767 0.0519 0.4568
Entamoeba histolytica tyrosine kinase, putative 0.0277 0.0027 0.0237
Schistosoma mansoni tyrosine kinase 0.0277 0.0027 0.0023
Echinococcus multilocularis serine:threonine protein kinase 3 0.0441 0.0192 0.0192
Loa Loa (eye worm) CAMK/PKD protein kinase 0.1037 0.0791 0.0868
Echinococcus multilocularis rho associated protein kinase 0.0683 0.0435 0.0435
Giardia lamblia Kinase, CMGC DYRK 0.031 0.006 0.0508
Schistosoma mansoni serine/threonine protein kinase 0.0683 0.0435 0.0997
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.031 0.006 0.0068
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0816 0.0568 0.0637
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.1633 0.1389 0.154
Echinococcus multilocularis tyrosine protein kinase shark 0.0759 0.0511 0.0511
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0821 0.0574 0.0625
Schistosoma mansoni protein kinase 0.2701 0.2461 0.5838
Trichomonas vaginalis STE family protein kinase 0.1435 0.119 1
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.198 0.1737 0.1931
Loa Loa (eye worm) hypothetical protein 0.0747 0.0499 0.0541
Loa Loa (eye worm) inward rectifying k channel family protein 1 0.0747 0.0499 0.0541
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.1205 0.096 0.096
Brugia malayi Temporarily assigned gene name protein 59 0.0772 0.0525 0.057
Echinococcus multilocularis fibroblast growth factor receptor 4 0.1608 0.1364 0.1364
Echinococcus multilocularis tyrosine protein kinase Src64B 0.1205 0.096 0.096
Echinococcus multilocularis integrin linked protein kinase 0.0277 0.0027 0.0027
Entamoeba histolytica receptor protein kinase, putative 0.0277 0.0027 0.0237
Echinococcus granulosus beta-adrenergic receptor kinase 0.0337 0.0087 0.0078
Echinococcus granulosus protein kinase C gamma type 0.0665 0.0417 0.0449
Loa Loa (eye worm) TK/FER protein kinase 0.0277 0.0027 0.0011
Trypanosoma brucei protein kinase, putative 0.0293 0.0043 0.0048
Echinococcus multilocularis tyrosine protein kinase Fyn 0.1205 0.096 0.096
Loa Loa (eye worm) hypothetical protein 0.0307 0.0057 0.0045
Entamoeba histolytica protein kinase domain containing protein 0.0693 0.0445 0.3916
Trichomonas vaginalis CAMK family protein kinase 0.0381 0.0132 0.1109
Brugia malayi Protein kinase domain containing protein 0.0392 0.0143 0.0141
Echinococcus granulosus insulin receptor 0.1542 0.1297 0.1437
Echinococcus granulosus cGMP dependent protein kinase 1 0.0305 0.0056 0.0043
Trichomonas vaginalis conserved hypothetical protein 0.0277 0.0027 0.0226
Entamoeba histolytica protein kinase domain containing protein 0.0277 0.0027 0.0237
Schistosoma mansoni protein kinase 0.0426 0.0177 0.0382
Loa Loa (eye worm) TK protein kinase 0.0277 0.0027 0.0011
Echinococcus granulosus dual specificity 0.031 0.006 0.0049
Brugia malayi Protein kinase domain containing protein 0.0277 0.0027 0.0011
Entamoeba histolytica protein kinase, putative 0.031 0.006 0.0532
Echinococcus multilocularis serine:threonine protein kinase N2 0.1301 0.1056 0.1056
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.029 0.0041 0.0026
Trypanosoma brucei Casein kinase II 0.0267 0.0017 0.0019
Trichomonas vaginalis TKL family protein kinase 0.0277 0.0027 0.0226
Echinococcus multilocularis dual specificity 0.031 0.006 0.006
Schistosoma mansoni vam6/vps39 related 0.0772 0.0525 0.1213
Trypanosoma brucei AGC/RSK family serine/threonine kinase, putative 0.0277 0.0027 0.003
Entamoeba histolytica protein kinase, putative 0.0426 0.0177 0.1557
Schistosoma mansoni serine/threonine protein kinase 0.1928 0.1685 0.3985
Brugia malayi Protein kinase domain containing protein 0.0277 0.0027 0.0011
Brugia malayi Protein kinase domain containing protein 0.7943 0.7724 0.865
Toxoplasma gondii AGC kinase 0.0757 0.0509 0.4667
Loa Loa (eye worm) AGC/AKT protein kinase 0.0807 0.056 0.0609
Schistosoma mansoni serine/threonine protein kinase 0.0443 0.0194 0.0421
Schistosoma mansoni tyrosine kinase 0.0486 0.0237 0.0526
Leishmania major casein kinase II, putative 0.0267 0.0017 0.0019
Brugia malayi Protein kinase domain containing protein 0.0277 0.0027 0.0011
Schistosoma mansoni hypothetical protein 0.0379 0.013 0.0269
Echinococcus granulosus tyrosine protein kinase shark 0.0759 0.0511 0.0554
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.0772 0.0525 0.0525
Brugia malayi Protein kinase domain containing protein 0.0915 0.0668 0.073
Brugia malayi hypothetical protein 0.0772 0.0525 0.057
Loa Loa (eye worm) hypothetical protein 0.0582 0.0334 0.0355
Echinococcus granulosus serine:threonine protein kinase 3 0.0441 0.0192 0.0196
Echinococcus multilocularis leucine rich repeat serine:threonine protein 0.0521 0.0273 0.0273
Brugia malayi Tyrosine-protein kinase F09A5.2 in chromosome X, putative 0.0277 0.0027 0.0011
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0277 0.0027 0.0237
Entamoeba histolytica tyrosine kinase, putative 0.0277 0.0027 0.0237
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0342 0.0092 0.0092
Echinococcus multilocularis casein kinase I gamma 0.0392 0.0143 0.0143
Loa Loa (eye worm) TK/Met protein kinase 0.0277 0.0027 0.0011
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0439 0.0189 0.0193
Echinococcus multilocularis serine:threonine protein kinase N2 0.062 0.0372 0.0372
Brugia malayi Immunoglobulin I-set domain containing protein 0.0747 0.0499 0.0541
Echinococcus granulosus neuroglian 0.0342 0.0092 0.0084
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.1203 0.0957 0.1072
Echinococcus granulosus MAM 0.0379 0.013 0.0126
Brugia malayi probable protein kinase 0.1836 0.1593 0.1769
Trichomonas vaginalis TKL family protein kinase 0.0277 0.0027 0.0226
Plasmodium vivax serine/threonine kinase-1, putative 0.1203 0.0957 0.8908
Echinococcus multilocularis tyrosine protein kinase Abl 0.1514 0.1269 0.1269
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0419 0.017 0.0172
Onchocerca volvulus 0.7943 0.7724 1
Schistosoma mansoni tyrosine kinase 0.4435 0.4203 1
Trypanosoma brucei casein kinase I, isoform 2 0.0701 0.0453 0.0507
Schistosoma mansoni ephrin receptor 0.0311 0.0062 0.0107
Trichomonas vaginalis TKL family protein kinase 0.0277 0.0027 0.0226
Onchocerca volvulus 0.0845 0.0597 0.0741
Echinococcus granulosus serine/threonine protein kinase 0.038 0.013 0.0127
Giardia lamblia Kinase, NEK 0.0307 0.0057 0.0482
Entamoeba histolytica protein kinase, putative 0.0277 0.0027 0.0237
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.1027 0.078 0.0856
Trichomonas vaginalis STE family protein kinase 0.1435 0.119 1
Schistosoma mansoni serine/threonine protein kinase 0.0277 0.0027 0.0023
Schistosoma mansoni serine/threonine protein kinase 0.0839 0.0592 0.1373
Schistosoma mansoni protein kinase 0.0277 0.0027 0.0023
Echinococcus multilocularis tyrosine protein kinase csk 0.0277 0.0027 0.0027
Schistosoma mansoni serine/threonine protein kinase 0.0701 0.0453 0.1041
Trichomonas vaginalis TKL family protein kinase 0.0277 0.0027 0.0226
Trichomonas vaginalis TKL family protein kinase 0.0277 0.0027 0.0226
Trichomonas vaginalis TKL family protein kinase 0.0277 0.0027 0.0226
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0693 0.0445 0.048
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0712 0.0464 0.0464
Brugia malayi Protein kinase c protein 2 0.0412 0.0162 0.0163
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.1027 0.078 0.0856
Loa Loa (eye worm) TK/FER protein kinase 0.0277 0.0027 0.0011
Echinococcus granulosus hypothetical protein 0.101 0.0764 0.0838
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0612 0.0364 0.0407
Schistosoma mansoni serine/threonine protein kinase 0.294 0.2701 0.6413
Trichomonas vaginalis CK1 family protein kinase 0.0701 0.0453 0.3806
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.1317 0.1072 0.1201
Echinococcus multilocularis PAK box P21 Rho binding 0.0402 0.0153 0.0153
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.0653 0.0405 0.0436
Brugia malayi cyclin-dependent kinase 9 0.0443 0.0194 0.0198
Brugia malayi Immunoglobulin I-set domain containing protein 0.3955 0.372 0.4156
Echinococcus multilocularis neurotracting:lsamp:neurotrimin:obcam 0.0307 0.0057 0.0057
Entamoeba histolytica casein kinase 1, putative 0.0701 0.0453 0.3984
Loa Loa (eye worm) hypothetical protein 0.0307 0.0057 0.0045
Trichomonas vaginalis TKL family protein kinase 0.0277 0.0027 0.0226
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0757 0.0509 0.0552
Loa Loa (eye worm) hypothetical protein 0.1097 0.0851 0.0936
Brugia malayi Immunoglobulin I-set domain containing protein 0.0342 0.0092 0.0084
Trichomonas vaginalis CMGC family protein kinase 0.0267 0.0017 0.0145
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0277 0.0027 0.0237
Brugia malayi intracellular kinase 0.1317 0.1072 0.1184
Onchocerca volvulus Serine\/threonine kinase homolog 0.0338 0.0088 0.008
Trichomonas vaginalis CAMK family protein kinase 0.0381 0.0132 0.1109
Echinococcus multilocularis peroxidasin 0.031 0.0061 0.0061
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0277 0.0027 0.0011
Entamoeba histolytica PH domain containing protein kinase, putative 0.038 0.013 0.1146
Entamoeba histolytica protein kinase, putative 0.0402 0.0153 0.1345
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0277 0.0027 0.0027
Trichomonas vaginalis CAMK family protein kinase 0.0381 0.0132 0.1109
Echinococcus multilocularis cyclin dependent kinase 1 0.0527 0.0279 0.0279
Echinococcus multilocularis protein kinase 0.0277 0.0027 0.0027
Schistosoma mansoni protein kinase 0.2592 0.2352 0.5578
Trichomonas vaginalis CMGC family protein kinase 0.0267 0.0017 0.0145
Brugia malayi Protein kinase domain containing protein 0.0527 0.0279 0.0294
Brugia malayi protein unc-22 0.0431 0.0182 0.0185
Trichomonas vaginalis CMGC family protein kinase 0.0267 0.0017 0.0145
Trichomonas vaginalis TKL family protein kinase 0.0277 0.0027 0.0226
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0527 0.0279 0.0294
Echinococcus multilocularis casein kinase i 0.0701 0.0453 0.0453
Echinococcus granulosus casein kinase I delta 0.0701 0.0453 0.0489
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.033 0.008 0.0071
Entamoeba histolytica serine/threonine kinase, putative 0.0277 0.0027 0.0237
Echinococcus granulosus roundabout 2 0.1053 0.0807 0.0886
Schistosoma mansoni serine/threonine protein kinase 0.3291 0.3053 0.7253
Schistosoma mansoni ste20-related kinase 0.0383 0.0134 0.0279
Echinococcus granulosus serine:threonine protein kinase 0.0372 0.0123 0.0119
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.2249 0.2007 0.2007
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0439 0.0189 0.0412
Loa Loa (eye worm) TK/FER protein kinase 0.0277 0.0027 0.0011
Trypanosoma brucei Pseudokinase, putative 0.0277 0.0027 0.003
Brugia malayi Protein kinase domain containing protein 0.1804 0.1561 0.1732
Trypanosoma cruzi casein kinase, putative 0.0701 0.0453 0.0507
Entamoeba histolytica protein kinase, putative 0.0757 0.0509 0.4481
Echinococcus multilocularis cyclin dependent kinase 0.0527 0.0279 0.0279
Trichomonas vaginalis CAMK family protein kinase 0.0381 0.0132 0.1109
Loa Loa (eye worm) RGC/RGC protein kinase 0.0277 0.0027 0.0011
Entamoeba histolytica protein kinase, putative 0.0277 0.0027 0.0237
Trichomonas vaginalis CAMK family protein kinase 0.0395 0.0145 0.1221
Entamoeba histolytica protein kinase domain containing protein 0.0381 0.0131 0.1156
Onchocerca volvulus 0.0522 0.0273 0.032
Trypanosoma cruzi polo-like protein kinase, putative 0.0351 0.0101 0.0113
Giardia lamblia Protein 21.1 0.0277 0.0027 0.0226
Leishmania major protein kinase A catalytic subunit isoform 2 0.0816 0.0568 0.0637
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0527 0.0279 0.0312
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.1317 0.1072 1
Entamoeba histolytica protein kinase domain containing protein 0.031 0.006 0.0532
Loa Loa (eye worm) TK/FER protein kinase 0.0522 0.0273 0.0288
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.914 0.8926 1
Echinococcus granulosus tyrosine protein kinase Src42A 0.0754 0.0506 0.0549
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0277 0.0027 0.0237
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.1192 0.0946 0.0946
Toxoplasma gondii AGC kinase 0.0816 0.0568 0.5225
Echinococcus granulosus twitchin 0.1108 0.0862 0.0948
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0693 0.0445 0.3916
Echinococcus granulosus natriuretic peptide receptor 1 0.0277 0.0027 0.0011
Schistosoma mansoni tyrosine kinase 0.2475 0.2235 0.5298
Echinococcus granulosus cyclin dependent kinase 9 0.0443 0.0194 0.0198
Schistosoma mansoni protein kinase 0.0277 0.0027 0.0023
Brugia malayi Receptor family ligand binding region containing protein 0.0277 0.0027 0.0011
Giardia lamblia Kinase, CMGC CDK 0.0527 0.0279 0.2343
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0612 0.0364 0.0389
Echinococcus granulosus cyclin dependent kinase 7 0.0706 0.0458 0.0495
Echinococcus multilocularis cyclin dependent kinase 1 0.0527 0.0279 0.0279
Onchocerca volvulus Tyrosine kinase homolog 0.3344 0.3107 0.4002
Loa Loa (eye worm) TK protein kinase 0.0613 0.0365 0.039
Brugia malayi Fibronectin type III domain containing protein 0.0747 0.0499 0.0541
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0816 0.0568 0.0568
Loa Loa (eye worm) hypothetical protein 0.0923 0.0676 0.074
Trichomonas vaginalis TKL family protein kinase 0.0277 0.0027 0.0226
Echinococcus multilocularis transfer RNA-Thr 0.195 0.1707 0.1707
Trypanosoma cruzi cdc2-related kinase 3 0.0527 0.0279 0.0312
Loa Loa (eye worm) hypothetical protein 0.1019 0.0772 0.0847
Echinococcus granulosus NDR protein kinase 0.062 0.0372 0.0398
Echinococcus multilocularis roundabout 2 0.0342 0.0092 0.0092
Plasmodium falciparum casein kinase 1 0.0701 0.0453 0.413
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0342 0.0092 0.0092
Entamoeba histolytica protein kinase, putative 0.1317 0.1072 0.9429
Loa Loa (eye worm) TKL/MLK/TAK1 protein kinase 0.0277 0.0027 0.0011
Brugia malayi Tyrosine-protein kinase PR2 0.0277 0.0027 0.0011
Schistosoma mansoni hypothetical protein 0.0379 0.013 0.0269
Echinococcus granulosus epidermal growth factor receptor 0.113 0.0884 0.0973
Loa Loa (eye worm) hypothetical protein 0.0307 0.0057 0.0045
Onchocerca volvulus 0.1317 0.1072 0.1358
Echinococcus granulosus protein kinase c epsilon type 0.0795 0.0548 0.0595
Giardia lamblia Kinase 0.0277 0.0027 0.0226
Echinococcus multilocularis slit 2 protein 0.0291 0.0042 0.0042
Trichomonas vaginalis AGC family protein kinase 0.0807 0.056 0.4703
Loa Loa (eye worm) hypothetical protein 0.0921 0.0674 0.0737
Echinococcus multilocularis aurora kinase A 0.0693 0.0445 0.0445
Giardia lamblia Kinase, PLK 0.0351 0.0101 0.0851
Loa Loa (eye worm) hypothetical protein 0.0923 0.0676 0.074
Entamoeba histolytica protein kinase domain containing protein 0.0277 0.0027 0.0237
Schistosoma mansoni tyrosine protein kinase 0.0277 0.0027 0.0023
Brugia malayi Doublecortin family protein 0.0323 0.0074 0.0063
Schistosoma mansoni tyrosine kinase 0.07 0.0452 0.1039
Loa Loa (eye worm) hypothetical protein 0.1543 0.1299 0.1439
Loa Loa (eye worm) hypothetical protein 0.0277 0.0027 0.0011
Trichomonas vaginalis serine/threonine-protein kinase wnk, putative 0.0277 0.0027 0.0226
Loa Loa (eye worm) AGC/NDR protein kinase 0.062 0.0372 0.0398
Echinococcus multilocularis dual specificity 0.1382 0.1137 0.1137
Entamoeba histolytica protein kinase, putative 0.0277 0.0027 0.0237
Entamoeba histolytica protein kinase domain containing protein 0.0277 0.0027 0.0237
Schistosoma mansoni serine/threonine protein kinase 0.0685 0.0437 0.1003
Trichomonas vaginalis TKL family protein kinase 0.0277 0.0027 0.0226
Brugia malayi Serine/threonine-protein kinase SULU 0.294 0.2701 0.3013
Schistosoma mansoni titin 0.0431 0.0182 0.0394
Trichomonas vaginalis CAMK family protein kinase 0.0381 0.0132 0.1109
Entamoeba histolytica protein kinase, putative 0.0277 0.0027 0.0237
Echinococcus multilocularis casein kinase I alpha 0.0701 0.0453 0.0453
Entamoeba histolytica serine/threonine protein kinase, putative 0.0351 0.0101 0.0891
Loa Loa (eye worm) TK/EGFR protein kinase 0.113 0.0884 0.0973
Trichomonas vaginalis CAMK family protein kinase 0.0351 0.0101 0.0851
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0469 0.022 0.0247
Echinococcus multilocularis serine:threonine protein kinase 0.0372 0.0123 0.0123
Loa Loa (eye worm) TK/FER protein kinase 0.0522 0.0273 0.0288
Trichomonas vaginalis TKL family protein kinase 0.0277 0.0027 0.0226
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0816 0.0568 0.0637
Loa Loa (eye worm) hypothetical protein 0.0582 0.0334 0.0355
Brugia malayi Protein kinase domain containing protein 0.0338 0.0088 0.008
Echinococcus multilocularis tyrosine protein kinase Fes:Fps 0.0277 0.0027 0.0027
Loa Loa (eye worm) CMGC/CLK protein kinase 0.1203 0.0957 0.1055
Echinococcus granulosus protein kinase 0.0277 0.0027 0.0011
Echinococcus multilocularis ephrin type A receptor 4 A 0.0348 0.0098 0.0098
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.914 0.8926 1
Schistosoma mansoni growth factor receptor-bound protein 0.0439 0.0189 0.0412
Echinococcus multilocularis dual specificity mitogen activated protein 0.1435 0.119 0.119
Loa Loa (eye worm) hypothetical protein 0.1019 0.0772 0.0847
Trichomonas vaginalis conserved hypothetical protein 0.0277 0.0027 0.0226
Schistosoma mansoni protein kinase 0.1064 0.0817 0.1912
Trichomonas vaginalis TKL family protein kinase 0.0277 0.0027 0.0226
Echinococcus multilocularis tyrosine protein kinase HCK 0.0767 0.0519 0.0519
Trichomonas vaginalis AGC family protein kinase 0.0693 0.0445 0.3742
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0534 0.0285 0.0301
Schistosoma mansoni protein kinase 0.0469 0.022 0.0485
Echinococcus granulosus tyrosine protein kinase csk 0.0277 0.0027 0.0011
Loa Loa (eye worm) hypothetical protein 0.0522 0.0273 0.0288
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.1382 0.1137 0.1274
Schistosoma mansoni tyrosine kinase 0.0277 0.0027 0.0023
Trichomonas vaginalis TKL family protein kinase 0.0277 0.0027 0.0226
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0337 0.0087 0.0078
Schistosoma mansoni serine/threonine protein kinase 0.1192 0.0946 0.222
Brugia malayi putative serine/threonine kinase SADA gamma 0.0381 0.0132 0.0129
Loa Loa (eye worm) hypothetical protein 0.0335 0.0086 0.0077
Loa Loa (eye worm) TK/KIN16 protein kinase 0.3955 0.372 0.4156
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.0277 0.0027 0.0011
Entamoeba histolytica tyrosine kinase, putative 0.0277 0.0027 0.0237
Plasmodium vivax tyrosine kinase-like protein, putative 0.0277 0.0027 0.0092
Trichomonas vaginalis protein tyrosine kinase, putative 0.0277 0.0027 0.0226
Giardia lamblia Kinase, AGC PKA 0.0816 0.0568 0.4777
Echinococcus granulosus neuroglian 0.0916 0.0669 0.0731
Schistosoma mansoni tyrosine kinase 0.2367 0.2125 0.5037
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0425 0.0176 0.1505
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0816 0.0568 0.0568
Trichomonas vaginalis AGC family protein kinase 0.062 0.0372 0.3124
Echinococcus multilocularis tyrosine protein kinase Blk 0.1012 0.0766 0.0766
Echinococcus granulosus TGF-beta receptor type-1 0.0997 0.0751 0.0823
Echinococcus granulosus dual specificity 0.031 0.006 0.0049
Entamoeba histolytica protein kinase domain containing protein 0.0277 0.0027 0.0237
Plasmodium falciparum serine/threonine protein kinase KIN 0.0381 0.0132 0.1087
Echinococcus granulosus tyrosine protein kinase HCK 0.0767 0.0519 0.0564
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0612 0.0364 0.3285
Schistosoma mansoni nephrin 0.0342 0.0092 0.0179
Loa Loa (eye worm) TK/ROR protein kinase 0.0481 0.0232 0.0241
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.198 0.1737 0.1931
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.2701 0.2461 0.2743
Loa Loa (eye worm) hypothetical protein 0.1644 0.14 0.1552
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.251 0.2269 0.2913
Brugia malayi C-terminal src kinase protein 1 0.0277 0.0027 0.0011
Entamoeba histolytica protein kinase, putative 0.0452 0.0203 0.1786
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0277 0.0027 0.0237
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0305 0.0056 0.0056
Loa Loa (eye worm) hypothetical protein 0.0379 0.013 0.0126
Brugia malayi protein-tyrosine kinase 0.1012 0.0766 0.084
Echinococcus multilocularis tyrosine protein kinase csk 0.0277 0.0027 0.0027
Echinococcus granulosus peroxidasin 0.031 0.0061 0.0049
Schistosoma mansoni serine/threonine protein kinase 0.1192 0.0946 0.222
Echinococcus multilocularis cyclin dependent kinase 19 0.1804 0.1561 0.1561
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.1317 0.1072 0.252
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.1608 0.1364 0.1364
Trichomonas vaginalis CAMK family protein kinase 0.0381 0.0132 0.1109
Brugia malayi Prion-like- 0.0307 0.0057 0.0045
Echinococcus multilocularis casein kinase I delta 0.0701 0.0453 0.0453
Loa Loa (eye worm) IKK protein kinase 0.7943 0.7724 0.865
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.3291 0.3053 0.3408
Loa Loa (eye worm) hypothetical protein 0.0747 0.0499 0.0541
Echinococcus granulosus dual specificity protein kinase clk2 0.1203 0.0957 0.1055
Entamoeba histolytica protein kinase domain containing protein 0.0469 0.022 0.1936
Loa Loa (eye worm) G protein-coupled receptor kinase 1 0.1489 0.1245 0.1378
Schistosoma mansoni protein kinase 0.1435 0.119 0.2802
Echinococcus granulosus tyrosine protein kinase Blk 0.1012 0.0766 0.084
Echinococcus multilocularis dual specificity 0.031 0.006 0.006
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0465 0.0216 0.0223
Loa Loa (eye worm) CMGC/CDK/CDK7 protein kinase 0.0706 0.0458 0.0495
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0305 0.0056 0.0056
Plasmodium falciparum serine/threonine protein kinase, putative 0.0693 0.0445 0.4058
Loa Loa (eye worm) AUR protein kinase 0.0693 0.0445 0.048
Entamoeba histolytica protein kinase, putative 0.0452 0.0203 0.1786
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0342 0.0092 0.0092
Trypanosoma cruzi cdc2-related kinase 1 0.0527 0.0279 0.0312
Entamoeba histolytica protein kinase domain containing protein 0.0277 0.0027 0.0237
Loa Loa (eye worm) hypothetical protein 0.0644 0.0396 0.0425
Onchocerca volvulus 0.0363 0.0114 0.0113
Trichomonas vaginalis TKL family protein kinase 0.0277 0.0027 0.0226
Trichomonas vaginalis CMGC family protein kinase 0.0267 0.0017 0.0145
Trichomonas vaginalis CAMK family protein kinase 0.0351 0.0101 0.0851
Echinococcus granulosus tyrosine protein kinase Fes:Fps 0.0277 0.0027 0.0011
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0381 0.0132 0.0148
Trypanosoma brucei protein kinase, putative 0.1317 0.1072 0.1201
Schistosoma mansoni serine/threonine protein kinase 0.0392 0.0143 0.0301
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0277 0.0027 0.0237
Echinococcus multilocularis cyclin dependent kinase 9 0.0443 0.0194 0.0194
Trichomonas vaginalis TKL family protein kinase 0.0277 0.0027 0.0226
Echinococcus multilocularis calcium activated potassium channel 0.0373 0.0124 0.0124
Trypanosoma cruzi polo-like protein kinase, putative 0.0351 0.0101 0.0113
Trichomonas vaginalis CMGC family protein kinase 0.031 0.006 0.0508
Echinococcus multilocularis phosphorylase kinase gamma subunit 0.0338 0.0088 0.0088
Loa Loa (eye worm) TK/FER protein kinase 0.0522 0.0273 0.0288
Echinococcus multilocularis tyrosine protein kinase Srms 0.1012 0.0766 0.0766
Brugia malayi SH2 domain containing protein 0.0859 0.0611 0.0667
Trichomonas vaginalis TKL family protein kinase 0.0277 0.0027 0.0226
Loa Loa (eye worm) hypothetical protein 0.1019 0.0772 0.0847
Toxoplasma gondii casein kinase I 0.0701 0.0453 0.413
Trichomonas vaginalis AGC family protein kinase 0.0807 0.056 0.4703
Brugia malayi Protein kinase domain containing protein 0.0277 0.0027 0.0011
Brugia malayi EGF-like domain containing protein 0.0291 0.0042 0.0028
Trichomonas vaginalis CMGC family protein kinase 0.031 0.006 0.0508
Loa Loa (eye worm) hypothetical protein 0.0512 0.0263 0.0276
Echinococcus multilocularis atrial natriuretic peptide receptor 1 0.0277 0.0027 0.0027
Echinococcus granulosus glycogen synthase kinase 3 beta 0.1317 0.1072 0.1184
Schistosoma mansoni serine/threonine protein kinase 0.0373 0.0124 0.0254
Brugia malayi Protein kinase domain containing protein 0.062 0.0372 0.0398
Brugia malayi Immunoglobulin I-set domain containing protein 0.0307 0.0057 0.0045
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.1382 0.1137 0.1257
Trichomonas vaginalis TKL family protein kinase 0.0277 0.0027 0.0226
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.031 0.006 0.041
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0712 0.0464 0.1067
Echinococcus multilocularis tyrosine protein kinase Fgr 0.1205 0.096 0.096
Loa Loa (eye worm) TK protein kinase 0.1012 0.0766 0.084
Trypanosoma cruzi aurora B kinase, putative 0.0693 0.0445 0.0499
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0754 0.0506 0.0506
Schistosoma mansoni serine/threonine protein kinase 0.0795 0.0548 0.1267
Entamoeba histolytica protein kinase, putative 0.0277 0.0027 0.0237
Loa Loa (eye worm) hypothetical protein 0.0381 0.0132 0.0129
Entamoeba histolytica casein kinase, putative 0.0701 0.0453 0.3984
Entamoeba histolytica protein kinase domain containing protein 0.0443 0.0194 0.1703
Trichomonas vaginalis TKL family protein kinase 0.0277 0.0027 0.0226
Entamoeba histolytica hypothetical protein 0.0277 0.0027 0.0237
Brugia malayi Dual specificity mitogen-activated protein kinase kinase mek-2 0.1435 0.119 0.1316
Echinococcus granulosus casein kinase I alpha 0.0701 0.0453 0.0489
Brugia malayi Protein kinase domain containing protein 0.0277 0.0027 0.0011
Brugia malayi Immunoglobulin I-set domain containing protein 0.0431 0.0182 0.0185
Trypanosoma cruzi casein kinase II, putative 0.0267 0.0017 0.0019
Loa Loa (eye worm) STE/STE7/MEK1 protein kinase 0.1435 0.119 0.1316
Trichomonas vaginalis TKL family protein kinase 0.0277 0.0027 0.0226
Plasmodium falciparum calcium-dependent protein kinase 2 0.0612 0.0364 0.3285
Brugia malayi Protein kinase domain containing protein 0.2701 0.2461 0.2743
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.1561 0.1316 0.1458
Echinococcus granulosus STE20 serine:threonine protein kinase 0.0704 0.0456 0.0493
Loa Loa (eye worm) TK protein kinase 0.1812 0.1569 0.1741
Echinococcus granulosus protein kinase 0.1064 0.0817 0.0898
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.1489 0.1245 0.1378
Schistosoma mansoni tyrosine kinase 0.0277 0.0027 0.0023
Echinococcus granulosus casein kinase I gamma 0.0392 0.0143 0.0141
Trichomonas vaginalis CAMK family protein kinase 0.0381 0.0132 0.1109
Schistosoma mansoni serine/threonine protein kinase 0.0816 0.0568 0.1317
Entamoeba histolytica protein kinase domain containing protein 0.0277 0.0027 0.0237
Trichomonas vaginalis CAMK family protein kinase 0.0381 0.0132 0.1109
Giardia lamblia Kinase, NEK 0.0277 0.0027 0.0226
Trichomonas vaginalis TKL family protein kinase 0.0277 0.0027 0.0226
Toxoplasma gondii hypothetical protein 0.0747 0.0499 0.4571
Entamoeba histolytica protein kinase 2, putative 0.033 0.008 0.0705
Entamoeba histolytica protein kinase, putative 0.0807 0.056 0.4922
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0816 0.0568 0.0637
Trichomonas vaginalis TKL family protein kinase 0.0277 0.0027 0.0226
Echinococcus multilocularis MAM 0.0379 0.013 0.013
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0527 0.0279 0.0294
Echinococcus multilocularis lachesin 0.0307 0.0057 0.0057
Trypanosoma cruzi casein kinase, putative 0.0701 0.0453 0.0507
Echinococcus granulosus leucine rich repeat serine:threonine protein 0.0521 0.0272 0.0286
Schistosoma mansoni serine/threonine protein kinase 0.0381 0.0132 0.0274
Brugia malayi serine/threonine-protein kinase plk-2 0.0351 0.0101 0.0094
Trypanosoma cruzi protein kinase, putative 0.0277 0.0027 0.003
Echinococcus granulosus cyclin dependent kinase 5 0.0527 0.0279 0.0294
Loa Loa (eye worm) hypothetical protein 0.119 0.0944 0.104
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.1382 0.1137 0.1274
Entamoeba histolytica leucine-rich repeat domain-containing protein 0.028 0.003 0.0266
Echinococcus granulosus tyrosine protein kinase Fyn 0.1205 0.096 0.1058
Schistosoma mansoni tyrosine kinase 0.0715 0.0467 0.1075
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0439 0.0189 0.0193
Trypanosoma cruzi Protein kinase B 0.038 0.013 0.0146
Toxoplasma gondii histone kinase SNF1, putative 0.0381 0.0132 0.1087
Brugia malayi Variant SH3 domain containing protein 0.0419 0.017 0.0172
Trichomonas vaginalis CAMK family protein kinase 0.0381 0.0132 0.1109
Loa Loa (eye worm) CMGC/DYRK/HIPK protein kinase 0.0381 0.0131 0.0128
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.914 0.8926 1
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.1608 0.1364 0.1511
Loa Loa (eye worm) hypothetical protein 0.0772 0.0525 0.057
Echinococcus granulosus homeodomain interacting protein kinase 3 0.0381 0.0131 0.0128
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0307 0.0057 0.0045
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0277 0.0027 0.0237
Entamoeba histolytica protein kinase, putative 0.0277 0.0027 0.0237
Onchocerca volvulus Basement membrane proteoglycan homolog 0.0307 0.0057 0.0039
Loa Loa (eye worm) TK protein kinase 0.0277 0.0027 0.0011
Schistosoma mansoni atypical protein kinase C 0.0892 0.0645 0.15
Entamoeba histolytica ankyrin repeat protein 0.0277 0.0027 0.0237
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0419 0.017 0.0365
Schistosoma mansoni tyrosine kinase 0.1205 0.096 0.2252
Echinococcus multilocularis casein kinase I delta 0.0701 0.0453 0.0453
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0419 0.017 0.0365
Loa Loa (eye worm) CMGC/CDK/CDK8 protein kinase 0.1804 0.1561 0.1732
Loa Loa (eye worm) TKL/RAF/KSR protein kinase 0.0277 0.0027 0.0011
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0816 0.0568 0.5225
Toxoplasma gondii aurora kinase 0.0693 0.0445 0.4058
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0623 0.0375 0.0402
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.2701 0.2461 0.2461
Brugia malayi Tyrosine-protein kinase abl-1 0.1514 0.1269 0.1406
Onchocerca volvulus 0.0522 0.0273 0.032
Plasmodium falciparum glycogen synthase kinase 3 0.1317 0.1072 1
Trichomonas vaginalis TKL family protein kinase 0.0277 0.0027 0.0226
Echinococcus granulosus aurora kinase A 0.0693 0.0445 0.048
Schistosoma mansoni tyrosine kinase 0.07 0.0452 0.1039
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0495 0.0247 0.0257
Brugia malayi Immunoglobulin I-set domain containing protein 0.0307 0.0057 0.0045
Echinococcus granulosus protein kinase shaggy 0.1317 0.1072 0.1184
Schistosoma mansoni serine/threonine protein kinase 0.0553 0.0304 0.0685
Brugia malayi Variant SH3 domain containing protein 0.0439 0.0189 0.0193
Schistosoma mansoni tyrosine kinase 0.0583 0.0335 0.0759
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0693 0.0445 0.4058
Echinococcus multilocularis casein kinase I alpha 0.0701 0.0453 0.0453
Echinococcus multilocularis serine:threonine protein kinase 0.0372 0.0123 0.0123
Trypanosoma brucei protein kinase, putative 0.0469 0.022 0.0247
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0859 0.0611 0.0667
Trichomonas vaginalis CAMK family protein kinase 0.0612 0.0364 0.3057
Leishmania major protein kinase A catalytic subunit 0.0816 0.0568 0.0637
Schistosoma mansoni serine/threonine protein kinase 0.0593 0.0345 0.0782
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0612 0.0364 0.3285
Trichomonas vaginalis AGC family protein kinase 0.0807 0.056 0.4703
Echinococcus granulosus serine:threonine protein kinase mig 15 0.1644 0.14 0.1552
Trichomonas vaginalis CMGC family protein kinase 0.0267 0.0017 0.0145
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0426 0.0177 0.0177
Echinococcus granulosus tyrosine protein kinase csk 0.0277 0.0027 0.0011
Schistosoma mansoni serine/threonine protein kinase 0.0816 0.0568 0.1317
Loa Loa (eye worm) protein kinase domain-containing protein 0.0277 0.0027 0.0011
Echinococcus multilocularis calcium dependent protein kinase 0.042 0.0171 0.0171
Loa Loa (eye worm) STE/STE20/SLK protein kinase 0.037 0.012 0.0116
Echinococcus multilocularis casein kinase I alpha 0.0701 0.0453 0.0453
Echinococcus multilocularis c src tyrosine kinase 0.0715 0.0467 0.0467
Echinococcus multilocularis STE20 serine:threonine protein kinase 0.0704 0.0456 0.0456
Loa Loa (eye worm) TK/ALK protein kinase 0.5607 0.5379 0.6019
Trichomonas vaginalis AGC family protein kinase 0.062 0.0372 0.3124
Trichomonas vaginalis conserved hypothetical protein 0.0277 0.0027 0.0226
Schistosoma mansoni septate junction protein 0.0307 0.0057 0.0095
Trichomonas vaginalis TKL family protein kinase 0.0277 0.0027 0.0226
Brugia malayi Protein kinase domain containing protein 0.0522 0.0273 0.0288
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.0593 0.0345 0.0368
Echinococcus multilocularis tyrosine protein kinase Src42A 0.1205 0.096 0.096
Loa Loa (eye worm) hypothetical protein 0.0277 0.0027 0.0011
Plasmodium falciparum calcium-dependent protein kinase 5 0.0612 0.0364 0.3285
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0553 0.0304 0.0304
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0623 0.0375 0.0375
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0701 0.0453 0.0489
Trichomonas vaginalis TKL family protein kinase 0.0277 0.0027 0.0226
Echinococcus granulosus calcium dependent protein kinase 0.042 0.0171 0.0172
Loa Loa (eye worm) CAMK/PHK protein kinase 0.0338 0.0088 0.008
Brugia malayi hypothetical protein 0.0379 0.013 0.0126
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0481 0.0232 0.0241
Loa Loa (eye worm) TK/DDR protein kinase 0.0352 0.0103 0.0096
Loa Loa (eye worm) AGC/PKA protein kinase 0.0816 0.0568 0.0619
Echinococcus multilocularis protein kinase shaggy 0.1317 0.1072 0.1072
Brugia malayi Furin-like cysteine rich region family protein 0.113 0.0884 0.0973

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 5.6234 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of binding or entry into cells for Lassa Virus. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID463114, AID540249] ChEMBL. No reference
Potency (functional) 10.4179 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 16.3601 uM PUBCHEM_BIOASSAY: qHTS screen for small molecules that inhibit ELG1-dependent DNA repair in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493107, AID493125] ChEMBL. No reference
Potency (functional) = 31.6228 um PUBCHEM_BIOASSAY: qHTS Assay for Promiscuous and Specific Inhibitors of Cruzain (without detergent). (Class of assay: confirmatory) [Related pubchem assays: 2158 (Confirmation qHTS Assay for Inhibitors of Cruzain), 2249 (Probe Development Summary of Promiscuous Inhibitors (Artifacts) of Cruzain), 2161 (qHTS Assay for Inhibitors of Papain: Counterscreen for Cruzain Assay), 1478 (qHTS Assay for Promiscuous and Specific Inhibitors of Cruzain (with detergent))] ChEMBL. No reference
Potency (functional) 37.933 uM PUBCHEM_BIOASSAY: qHTS profiling assay for firefly luciferase inhibitor/activator using purified enzyme and Km concentrations of substrates (counterscreen for miR-21 project). (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2288, AID2289, AID2598, AID411] ChEMBL. No reference
Potency (functional) 84.9214 uM PubChem BioAssay. qHTS Assay to Find Inhibitors of Pin1. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 89.1251 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Iota. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588623] ChEMBL. No reference
Potency (functional) = 112.2018 um PUBCHEM_BIOASSAY: qHTS Inhibitors of AmpC Beta-Lactamase (assay with detergent). (Class of assay: confirmatory) [Related pubchem assays: 1002 (Confirmation Concentration-Response Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent)), 585 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay without detergent) - a screen old NIH MLSMR collection), 584 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay with detergent) - a screen of the old NIH MLSMR collection), 1003 (Confirmation Cuvette-Based Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent))] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23
Homo sapiens ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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