Detailed information for compound 1411307

Basic information

Technical information
  • TDR Targets ID: 1411307
  • Name: 1-(2-prop-2-enylsulfanylbenzimidazol-1-yl)-3- (3,4,5-trimethoxyphenyl)prop-2-en-1-one
  • MW: 410.486 | Formula: C22H22N2O4S
  • H donors: 0 H acceptors: 2 LogP: 4.81 Rotable bonds: 9
    Rule of 5 violations (Lipinski): 1
  • SMILES: C=CCSc1nc2c(n1C(=O)/C=C/c1cc(OC)c(c(c1)OC)OC)cccc2
  • InChi: 1S/C22H22N2O4S/c1-5-12-29-22-23-16-8-6-7-9-17(16)24(22)20(25)11-10-15-13-18(26-2)21(28-4)19(14-15)27-3/h5-11,13-14H,1,12H2,2-4H3/b11-10+
  • InChiKey: JMBYFKBGOMJGFM-ZHACJKMWSA-N  


Substructure search Similarity search

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Synonyms

  • (E)-1-(2-prop-2-enylsulfanylbenzimidazol-1-yl)-3-(3,4,5-trimethoxyphenyl)prop-2-en-1-one
  • 1-(2-allylsulfanylbenzimidazol-1-yl)-3-(3,4,5-trimethoxyphenyl)prop-2-en-1-one
  • (E)-1-(2-allylsulfanylbenzimidazol-1-yl)-3-(3,4,5-trimethoxyphenyl)prop-2-en-1-one
  • 1-[2-(allylthio)-1-benzimidazolyl]-3-(3,4,5-trimethoxyphenyl)prop-2-en-1-one
  • (E)-1-[2-(allylthio)-1-benzimidazolyl]-3-(3,4,5-trimethoxyphenyl)prop-2-en-1-one
  • (E)-1-[2-(allylthio)benzimidazol-1-yl]-3-(3,4,5-trimethoxyphenyl)prop-2-en-1-one
  • 1-[2-(allylthio)benzimidazol-1-yl]-3-(3,4,5-trimethoxyphenyl)prop-2-en-1-one
  • SMR000198113
  • ZINC04264145
  • 2-(allylthio)-1-[3-(3,4,5-trimethoxyphenyl)acryloyl]-1H-benzimidazole
  • MLS000577033

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens ATPase family, AAA domain containing 5 Starlite/ChEMBL No references
Mus musculus heat shock factor 1 Starlite/ChEMBL No references
Homo sapiens RAB9A, member RAS oncogene family Starlite/ChEMBL No references
Homo sapiens apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G Starlite/ChEMBL No references
Homo sapiens isocitrate dehydrogenase 1 (NADP+), soluble Starlite/ChEMBL No references
Homo sapiens polymerase (DNA directed) iota Starlite/ChEMBL No references
Homo sapiens cytochrome P450, family 2, subfamily C, polypeptide 9 Starlite/ChEMBL No references
Homo sapiens cytochrome P450, family 2, subfamily C, polypeptide 19 Starlite/ChEMBL No references
Homo sapiens X-box binding protein 1 Starlite/ChEMBL No references
Homo sapiens vitamin D (1,25- dihydroxyvitamin D3) receptor Starlite/ChEMBL No references
Homo sapiens heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) Starlite/ChEMBL No references
Mus musculus RAR-related orphan receptor gamma Starlite/ChEMBL No references
Homo sapiens cytochrome P450, family 3, subfamily A, polypeptide 4 Starlite/ChEMBL No references
Homo sapiens lamin A/C Starlite/ChEMBL No references
Homo sapiens neuropeptide S receptor 1 Starlite/ChEMBL No references
Homo sapiens geminin, DNA replication inhibitor Starlite/ChEMBL No references
Homo sapiens SMAD family member 2 Starlite/ChEMBL No references
Mus musculus DNA-damage inducible transcript 3 Starlite/ChEMBL No references
Homo sapiens ataxin 2 Starlite/ChEMBL No references
Homo sapiens glycoprotein hormones, alpha polypeptide Starlite/ChEMBL No references
Homo sapiens nuclear factor, erythroid 2-like 2 Starlite/ChEMBL No references
Homo sapiens cytochrome P450, family 1, subfamily A, polypeptide 2 Starlite/ChEMBL No references
Homo sapiens apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3D Starlite/ChEMBL No references
Homo sapiens MDM2 proto-oncogene, E3 ubiquitin protein ligase Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Neospora caninum Heat shock protein 70 (Precursor), related Get druggable targets OG5_126588 All targets in OG5_126588
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_129203 All targets in OG5_129203
Trichomonas vaginalis heat shock protein, putative Get druggable targets OG5_126588 All targets in OG5_126588
Trypanosoma congolense isocitrate dehydrogenase, putative Get druggable targets OG5_127057 All targets in OG5_127057
Toxoplasma gondii chaperonin protein BiP Get druggable targets OG5_126588 All targets in OG5_126588
Entamoeba histolytica heat shock protein 70, putative Get druggable targets OG5_126588 All targets in OG5_126588
Candida albicans cytosolic NADP-specific isocitrate dehydrogenase. Get druggable targets OG5_127057 All targets in OG5_127057
Leishmania infantum glucose-regulated protein 78, putative Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus granulosus heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Candida albicans HSP70 Get druggable targets OG5_126588 All targets in OG5_126588
Leishmania major heat-shock protein hsp70, putative Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus granulosus heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Loa Loa (eye worm) intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Trichomonas vaginalis heat shock protein 70kD, putative Get druggable targets OG5_126588 All targets in OG5_126588
Plasmodium falciparum heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus multilocularis neuropeptide s receptor Get druggable targets OG5_136011 All targets in OG5_136011
Echinococcus multilocularis heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Entamoeba histolytica 70 kDa heat shock protein, putative Get druggable targets OG5_126588 All targets in OG5_126588
Candida albicans closely related to C.maltosa N-alkane-inducible cytochrome P-450, alkane hydroxylating monooxygenase CYP52A3-b aka P450Alk1A (BA Get druggable targets OG5_126554 All targets in OG5_126554
Echinococcus granulosus heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus multilocularis X box binding protein 1 Get druggable targets OG5_134980 All targets in OG5_134980
Schistosoma mansoni heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus multilocularis heat shock 70 kDa protein 1A:1B Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus granulosus heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Schistosoma japonicum hypothetical protein Get druggable targets OG5_126588 All targets in OG5_126588
Trichomonas vaginalis heat shock protein, putative Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus granulosus Heat shock 70 kDa protein Get druggable targets OG5_126588 All targets in OG5_126588
Trypanosoma congolense luminal binding protein 1 (BiP), putative Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus multilocularis heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Schistosoma japonicum Intermediate filament protein ifa-1, putative Get druggable targets OG5_128723 All targets in OG5_128723
Trypanosoma congolense isocitrate dehydrogenase, putative Get druggable targets OG5_127057 All targets in OG5_127057
Loa Loa (eye worm) intermediate filament tail domain-containing protein Get druggable targets OG5_128723 All targets in OG5_128723
Babesia bovis dnaK protein Get druggable targets OG5_126588 All targets in OG5_126588
Trichomonas vaginalis microsomal stress 70 protein ATPase core precursor, putative Get druggable targets OG5_126588 All targets in OG5_126588
Cryptosporidium parvum heat shock 70 (HSP70) protein Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus granulosus heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Neospora caninum Heat shock protein 70, related Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus multilocularis heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Candida albicans cytochrome P450 556 Get druggable targets OG5_126554 All targets in OG5_126554
Echinococcus multilocularis heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Schistosoma japonicum IPR011700,Basic leucine zipper;IPR004827,Basic-leucine zipper (bZIP) transcription factor;IPR008917,Eukaryotic transcription fac Get druggable targets OG5_134980 All targets in OG5_134980
Echinococcus multilocularis heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus granulosus heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Brugia malayi Cytochrome P450 family protein Get druggable targets OG5_126554 All targets in OG5_126554
Trichomonas vaginalis heat shock protein, putative Get druggable targets OG5_126588 All targets in OG5_126588
Schistosoma mansoni lamin Get druggable targets OG5_128723 All targets in OG5_128723
Babesia bovis isocitrate dehydrogenase, NADP-dependent family protein Get druggable targets OG5_127057 All targets in OG5_127057
Loa Loa (eye worm) cytochrome P450 family protein Get druggable targets OG5_126554 All targets in OG5_126554
Entamoeba histolytica heat shock protein70, hsp70A2, putative Get druggable targets OG5_126588 All targets in OG5_126588
Leishmania donovani luminal binding protein 1 (BiP), putative Get druggable targets OG5_126588 All targets in OG5_126588
Entamoeba histolytica heat shock protein 70, putative Get druggable targets OG5_126588 All targets in OG5_126588
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 Get druggable targets OG5_126554 All targets in OG5_126554
Schistosoma japonicum expressed protein Get druggable targets OG5_128723 All targets in OG5_128723
Trypanosoma congolense heat shock 70 kDa protein, putative Get druggable targets OG5_126588 All targets in OG5_126588
Cryptosporidium hominis heat shock protein Get druggable targets OG5_126588 All targets in OG5_126588
Trichomonas vaginalis heat shock protein 70 (HSP70)-4, putative Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus granulosus heat shock protein 70b Get druggable targets OG5_126588 All targets in OG5_126588
Entamoeba histolytica heat shock protein 70 family Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus granulosus heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Leishmania infantum heat shock protein 70-related protein Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus multilocularis heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus multilocularis neuropeptide receptor A26 Get druggable targets OG5_136011 All targets in OG5_136011
Brugia malayi Isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Leishmania braziliensis heat-shock protein hsp70, putative Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus granulosus heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Trypanosoma brucei isocitrate dehydrogenase, putative Get druggable targets OG5_127057 All targets in OG5_127057
Loa Loa (eye worm) heat shock 70kDa protein 5 Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus granulosus heat shock protein 71 kDa protein Get druggable targets OG5_126588 All targets in OG5_126588
Trichomonas vaginalis heat shock protein, putative Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus multilocularis heat shock protein 71 kDa protein Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus granulosus neuropeptide receptor A26 Get druggable targets OG5_136011 All targets in OG5_136011
Trichomonas vaginalis heat shock protein, putative Get druggable targets OG5_126588 All targets in OG5_126588
Candida albicans C terminus of cytosolic NADP-specific isocitrate dehydrogenase. Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus granulosus heat shock protein Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus multilocularis heat shock 70 kda protein 1a Get druggable targets OG5_126588 All targets in OG5_126588
Schistosoma mansoni heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus multilocularis heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Schistosoma japonicum ko:K07611 lamin, putative Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus granulosus Heat shock 70 kDa protein 4 Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus granulosus lamin dm0 Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus granulosus Heat shock 70 kDa protein 4 Get druggable targets OG5_126588 All targets in OG5_126588
Leishmania infantum heat-shock protein hsp70, putative Get druggable targets OG5_126588 All targets in OG5_126588
Trypanosoma cruzi glucose-regulated protein 78, putative Get druggable targets OG5_126588 All targets in OG5_126588
Onchocerca volvulus Heat shock factor protein 2 homolog Get druggable targets OG5_129203 All targets in OG5_129203
Echinococcus granulosus heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Leishmania mexicana heat-shock protein hsp70, putative Get druggable targets OG5_126588 All targets in OG5_126588
Candida albicans Cytoplasmic chaperone Get druggable targets OG5_126588 All targets in OG5_126588
Trypanosoma cruzi heat shock protein 70 (hsp70), putative Get druggable targets OG5_126588 All targets in OG5_126588
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus granulosus heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Schistosoma japonicum expressed protein Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus multilocularis heat shock protein 70 related Get druggable targets OG5_126588 All targets in OG5_126588
Onchocerca volvulus Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus multilocularis heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Candida albicans Mitochondrial NADP-specific isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus multilocularis Heat shock 70 kDa protein Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus multilocularis Heat shock 70 kDa protein Get druggable targets OG5_126588 All targets in OG5_126588
Leishmania braziliensis isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Schistosoma japonicum ko:K09490 heat shock 70kDa protein 5, putative Get druggable targets OG5_126588 All targets in OG5_126588
Plasmodium knowlesi isocitrate dehydrogenase [NADP], mitochondrial, putative Get druggable targets OG5_127057 All targets in OG5_127057
Trypanosoma brucei gambiense heat shock 70 kDa protein, putative Get druggable targets OG5_126588 All targets in OG5_126588
Trichomonas vaginalis heat shock protein, putative Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus multilocularis heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Plasmodium knowlesi heat shock protein, putative Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus granulosus intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus multilocularis Heat Shock protein family member (hsp 3) Get druggable targets OG5_126588 All targets in OG5_126588
Trypanosoma cruzi cytochrome P450, putative Get druggable targets OG5_126554 All targets in OG5_126554
Giardia lamblia Cytosolic HSP70 Get druggable targets OG5_126588 All targets in OG5_126588
Schistosoma mansoni hypothetical protein Get druggable targets OG5_134980 All targets in OG5_134980
Schistosoma mansoni heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Theileria parva isocitrate dehydrogenase (NADP+), putative Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Loa Loa (eye worm) MH2 domain-containing protein Get druggable targets OG5_131716 All targets in OG5_131716
Plasmodium yoelii heat shock protein Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus multilocularis heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Plasmodium vivax heat shock protein 70, putative Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus granulosus heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Brugia malayi Cytochrome P450 family protein Get druggable targets OG5_126554 All targets in OG5_126554
Toxoplasma gondii heat shock protein HSP70 Get druggable targets OG5_126588 All targets in OG5_126588
Loa Loa (eye worm) cytochrome P450 family protein Get druggable targets OG5_126582 All targets in OG5_126582
Candida albicans Cytoplasmic chaperone Get druggable targets OG5_126588 All targets in OG5_126588
Candida albicans similar to C.maltosa N-alkane inducible cytochrome P-450, ALK8 CYP52A11 Get druggable targets OG5_126554 All targets in OG5_126554
Leishmania major heat shock protein 70-related protein Get druggable targets OG5_126588 All targets in OG5_126588
Entamoeba histolytica heat shock protein 70 family Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus multilocularis heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Trypanosoma brucei gambiense glucose-regulated protein 78, putative,luminal binding protein 1 (BiP), putative Get druggable targets OG5_126588 All targets in OG5_126588
Leishmania mexicana cytochrome p450-like protein Get druggable targets OG5_126554 All targets in OG5_126554
Giardia lamblia Bip Get druggable targets OG5_126588 All targets in OG5_126588
Candida albicans similar to S. cerevisiae KAR2 (YJL034W) HSP70/ BiP family ATPase and chaperone involved in translocation of nascent polypeptides Get druggable targets OG5_126588 All targets in OG5_126588
Loa Loa (eye worm) transcription factor SMAD2 Get druggable targets OG5_131716 All targets in OG5_131716
Echinococcus multilocularis Heat shock 70 kDa protein Get druggable targets OG5_126588 All targets in OG5_126588
Neospora caninum hypothetical protein Get druggable targets OG5_127057 All targets in OG5_127057
Candida albicans heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Candida albicans similar to S. cerevisiae Heat Shock Factor HSF1 (YGL073W) RNA Pol II transcriptional activator Get druggable targets OG5_129203 All targets in OG5_129203
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Leishmania mexicana heat shock protein 70-related protein Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus multilocularis Heat shock 70 kDa protein Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus granulosus heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Trichomonas vaginalis heat shock protein, putative Get druggable targets OG5_126588 All targets in OG5_126588
Trypanosoma cruzi cytochrome P450, putative Get druggable targets OG5_126554 All targets in OG5_126554
Echinococcus granulosus heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus multilocularis Heat shock 70 kDa protein 4 Get druggable targets OG5_126588 All targets in OG5_126588
Leishmania donovani heat-shock protein hsp70, putative Get druggable targets OG5_126588 All targets in OG5_126588
Leishmania major cytochrome p450-like protein Get druggable targets OG5_126554 All targets in OG5_126554
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial Get druggable targets OG5_127057 All targets in OG5_127057
Brugia malayi heat shock 70 kDa protein Get druggable targets OG5_126588 All targets in OG5_126588
Leishmania infantum isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Plasmodium falciparum heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus granulosus heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus multilocularis Heat shock 70 kDa protein 4 Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus multilocularis heat shock protein kDa heat shock kDa protein Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus multilocularis lamin dm0 Get druggable targets OG5_128723 All targets in OG5_128723
Plasmodium vivax heat shock 70 kDa protein, putative Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus granulosus lamin Get druggable targets OG5_128723 All targets in OG5_128723
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) Get druggable targets OG5_127057 All targets in OG5_127057
Entamoeba histolytica heat shock transcription factor, putative Get druggable targets OG5_129203 All targets in OG5_129203
Cryptosporidium parvum heat shock protein, Hsp70 Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus multilocularis cytoplasmic intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus multilocularis heat shock protein kDa heat shock kDa protein Get druggable targets OG5_126588 All targets in OG5_126588
Trypanosoma congolense heat shock 70 kDa protein, putative Get druggable targets OG5_126588 All targets in OG5_126588
Leishmania infantum heat-shock protein hsp70, putative Get druggable targets OG5_126588 All targets in OG5_126588
Toxoplasma gondii isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Plasmodium yoelii isocitrate dehydrogenase, NADP-dependent Get druggable targets OG5_127057 All targets in OG5_127057
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus multilocularis heat shock protein 71 kDa protein Get druggable targets OG5_126588 All targets in OG5_126588
Schistosoma mansoni NADP-specific isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus multilocularis Heat shock protein 70 (HSP70) Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus multilocularis heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus granulosus 3'partial|5'partial|heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus granulosus heat shock protein kDa Get druggable targets OG5_126588 All targets in OG5_126588
Loa Loa (eye worm) CYP4Cod1 Get druggable targets OG5_126554 All targets in OG5_126554
Trypanosoma cruzi isocitrate dehydrogenase, putative Get druggable targets OG5_127057 All targets in OG5_127057
Candida albicans heat shock protein Get druggable targets OG5_126588 All targets in OG5_126588
Schistosoma japonicum similar to Heat shock 70 kDa protein homolog, putative Get druggable targets OG5_126588 All targets in OG5_126588
Candida albicans Mitochondrial NADP-specific isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Plasmodium yoelii heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus granulosus Heat Shock protein family member hsp 3 Get druggable targets OG5_126588 All targets in OG5_126588
Brugia malayi Intermediate filament tail domain containing protein Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus granulosus Heat shock 70 kDa protein 4 Get druggable targets OG5_126588 All targets in OG5_126588
Leishmania major heat-shock protein hsp70, putative Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus granulosus heat shock kda protein Get druggable targets OG5_126588 All targets in OG5_126588
Trypanosoma brucei heat shock protein 70 (hsp70), putative Get druggable targets OG5_126588 All targets in OG5_126588
Leishmania infantum heat-shock protein hsp70, putative Get druggable targets OG5_126588 All targets in OG5_126588
Trypanosoma congolense luminal binding protein 1 (BiP), putative Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus multilocularis heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Neospora caninum Isocitrate dehydrogenase-like protein, related Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus multilocularis heat shock protein 70b Get druggable targets OG5_126588 All targets in OG5_126588
Leishmania braziliensis heat shock protein 70-related protein Get druggable targets OG5_126588 All targets in OG5_126588
Schistosoma japonicum IPR011700,Basic leucine zipper;IPR004827,Basic-leucine zipper (bZIP) transcription factor;IPR008917,Eukaryotic transcription fac Get druggable targets OG5_134980 All targets in OG5_134980
Schistosoma japonicum Lamin-C, putative Get druggable targets OG5_128723 All targets in OG5_128723
Trichomonas vaginalis heat shock protein 70 (HSP70)-4, putative Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus granulosus heat shock protein 71 kDa protein Get druggable targets OG5_126588 All targets in OG5_126588
Trichomonas vaginalis heat shock protein 70 (HSP70)-4, putative Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus granulosus heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus granulosus NADP dependent isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Schistosoma mansoni intermediate filament proteins Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus granulosus neuropeptide s receptor Get druggable targets OG5_136011 All targets in OG5_136011
Trypanosoma brucei luminal binding protein 1 (BiP), putative Get druggable targets OG5_126588 All targets in OG5_126588
Trypanosoma brucei luminal binding protein 1 (BiP), putative Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus granulosus heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Trypanosoma congolense cytochrome P450, putative Get druggable targets OG5_126554 All targets in OG5_126554
Echinococcus multilocularis Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus granulosus heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Trypanosoma brucei gambiense isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus granulosus Heat shock 70 kDa protein Get druggable targets OG5_126588 All targets in OG5_126588
Plasmodium berghei isocitrate dehydrogenase [NADP], mitochondrial, putative Get druggable targets OG5_127057 All targets in OG5_127057
Trichomonas vaginalis heat shock protein, putative Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus multilocularis Heat shock 70 kDa protein Get druggable targets OG5_126588 All targets in OG5_126588
Schistosoma japonicum IPR000276,Rhodopsin-like GPCR superfamily,domain-containing Get druggable targets OG5_136011 All targets in OG5_136011
Echinococcus granulosus Heat shock 70 kDa protein 4 Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core Get druggable targets OG5_139225 All targets in OG5_139225
Echinococcus multilocularis heat shock protein Get druggable targets OG5_126588 All targets in OG5_126588
Loa Loa (eye worm) cytochrome P450 family protein Get druggable targets OG5_126554 All targets in OG5_126554
Trypanosoma brucei gambiense isocitrate dehydrogenase, putative Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus granulosus X box binding protein 1 Get druggable targets OG5_134980 All targets in OG5_134980
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus granulosus heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus multilocularis heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Candida albicans similar to S. cerevisiae Heat Shock Factor HSF1 (YGL073W) RNA Pol II transcriptional activator Get druggable targets OG5_129203 All targets in OG5_129203
Entamoeba histolytica hypothetical protein Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus multilocularis heat shock kda protein Get druggable targets OG5_126588 All targets in OG5_126588
Candida albicans similar to C.maltosa N-alkane inducible cytochrome P-450, ALK8 CYP52A11 Get druggable targets OG5_126554 All targets in OG5_126554
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus granulosus heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus multilocularis isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Brugia malayi HSF-type DNA-binding domain containing protein Get druggable targets OG5_129203 All targets in OG5_129203
Echinococcus multilocularis Get druggable targets OG5_126588 All targets in OG5_126588
Leishmania mexicana heat-shock protein hsp70, putative Get druggable targets OG5_126588 All targets in OG5_126588
Plasmodium knowlesi heat shock protein 70, putative Get druggable targets OG5_126588 All targets in OG5_126588
Entamoeba histolytica heat shock protein70, hsp70A2, putative Get druggable targets OG5_126588 All targets in OG5_126588
Entamoeba histolytica heat shock protein70, hsp70A2, putative Get druggable targets OG5_126588 All targets in OG5_126588
Candida albicans HSP70 Get druggable targets OG5_126588 All targets in OG5_126588
Entamoeba histolytica heat shock protein 70, putative Get druggable targets OG5_126588 All targets in OG5_126588
Leishmania donovani heat-shock protein hsp70, putative Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus multilocularis heat shock protein 70 related Get druggable targets OG5_126588 All targets in OG5_126588
Leishmania major glucose-regulated protein 78, putative Get druggable targets OG5_126588 All targets in OG5_126588
Trypanosoma cruzi heat shock protein 70 (hsp70), putative Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus granulosus heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus granulosus heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Leishmania mexicana glucose-regulated protein 78, putative Get druggable targets OG5_126588 All targets in OG5_126588
Trypanosoma brucei heat shock 70 kDa protein, putative Get druggable targets OG5_126588 All targets in OG5_126588
Leishmania braziliensis cytochrome p450-like protein Get druggable targets OG5_126554 All targets in OG5_126554
Brugia malayi Cytochrome P450 family protein Get druggable targets OG5_126582 All targets in OG5_126582
Echinococcus multilocularis heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Trichomonas vaginalis heat shock protein 70kD, putative Get druggable targets OG5_126588 All targets in OG5_126588
Trypanosoma brucei gambiense glucose-regulated protein 78, putative,luminal binding protein 1 (BiP), putative Get druggable targets OG5_126588 All targets in OG5_126588
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126554 All targets in OG5_126554
Echinococcus multilocularis heat shock 70 kDa protein 1 Get druggable targets OG5_126588 All targets in OG5_126588
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) Get druggable targets OG5_127057 All targets in OG5_127057
Plasmodium berghei heat shock protein 70, putative Get druggable targets OG5_126588 All targets in OG5_126588
Trypanosoma brucei heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Entamoeba histolytica heat shock protein 70, putative Get druggable targets OG5_126588 All targets in OG5_126588
Onchocerca volvulus Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus multilocularis heat shock protein 70 related Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus multilocularis Heat shock 70 kDa protein Get druggable targets OG5_126588 All targets in OG5_126588
Trypanosoma brucei gambiense cytochrome P450, putative Get druggable targets OG5_126554 All targets in OG5_126554
Schistosoma japonicum ko:K00031 isocitrate dehydrogenase [EC1.1.1.42], putative Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus granulosus heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Brugia malayi intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Trypanosoma congolense heat shock 70 kDa protein, putative Get druggable targets OG5_126588 All targets in OG5_126588
Trypanosoma congolense heat shock 70 kDa protein, putative Get druggable targets OG5_126588 All targets in OG5_126588
Leishmania donovani heat shock protein 70-related protein Get druggable targets OG5_126588 All targets in OG5_126588
Plasmodium yoelii isocitrate dehydrogenase, NADP-dependent, putative Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus granulosus heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Leishmania donovani isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Theileria parva heat shock protein 70, putative Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus granulosus heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Entamoeba histolytica heat shock transcription factor, putative Get druggable targets OG5_129203 All targets in OG5_129203
Echinococcus multilocularis Heat shock 70 kDa protein 4 Get druggable targets OG5_126588 All targets in OG5_126588
Entamoeba histolytica heat shock transcription factor, putative Get druggable targets OG5_129203 All targets in OG5_129203
Trichomonas vaginalis heat shock protein, putative Get druggable targets OG5_126588 All targets in OG5_126588
Babesia bovis heat shock protein 70 precursor, putative Get druggable targets OG5_126588 All targets in OG5_126588
Trypanosoma brucei cytochrome P450, putative Get druggable targets OG5_126554 All targets in OG5_126554
Echinococcus multilocularis Get druggable targets OG5_126588 All targets in OG5_126588
Leishmania infantum heat-shock protein hsp70, putative Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus granulosus heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Plasmodium berghei heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Schistosoma japonicum similar to Heat shock 70 kDa protein cognate 4, putative Get druggable targets OG5_126588 All targets in OG5_126588
Candida albicans cytochrome P450 56 Get druggable targets OG5_126554 All targets in OG5_126554
Echinococcus granulosus heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Cryptosporidium hominis heat shock protein 70 precursor Get druggable targets OG5_126588 All targets in OG5_126588
Leishmania braziliensis glucose-regulated protein 78, putative Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus granulosus heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus multilocularis musashi Get druggable targets OG5_128723 All targets in OG5_128723
Brugia malayi heat shock 70 kDa protein C precursor Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus multilocularis heat shock protein 70 related Get druggable targets OG5_126588 All targets in OG5_126588
Leishmania donovani cytochrome p450-like protein Get druggable targets OG5_126554 All targets in OG5_126554
Candida albicans N terminus of cytosolic NADP-specific isocitrate dehydrogenase. Get druggable targets OG5_127057 All targets in OG5_127057
Loa Loa (eye worm) isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Leishmania mexicana isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Plasmodium falciparum heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Candida albicans heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Theileria parva heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Toxoplasma gondii isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus granulosus cytoplasmic intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Onchocerca volvulus Get druggable targets OG5_126588 All targets in OG5_126588
Brugia malayi MH2 domain containing protein Get druggable targets OG5_131716 All targets in OG5_131716
Entamoeba histolytica heat shock protein70, hsp70A2, putative Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus multilocularis heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus multilocularis lamin Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma mansoni lamin Get druggable targets OG5_128723 All targets in OG5_128723
Leishmania infantum cytochrome p450-like protein Get druggable targets OG5_126554 All targets in OG5_126554
Brugia malayi isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Brugia malayi MH2 domain containing protein SMAD family member 2 467 aa 405 aa 31.6 %
Toxoplasma gondii intraflagellar transport protein 172, putative glycoprotein hormones, alpha polypeptide 116 aa 94 aa 26.6 %
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 cytochrome P450, family 2, subfamily C, polypeptide 9 490 aa 441 aa 21.8 %
Brugia malayi Cytochrome P450 family protein cytochrome P450, family 1, subfamily A, polypeptide 2 516 aa 470 aa 26.2 %
Leishmania major cytochrome p450-like protein cytochrome P450, family 2, subfamily C, polypeptide 19 490 aa 411 aa 23.1 %
Plasmodium falciparum heat shock protein 70 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 654 aa 613 aa 51.9 %
Brugia malayi cytochrome P450 cytochrome P450, family 3, subfamily A, polypeptide 4 502 aa 492 aa 24.2 %
Plasmodium falciparum ras-related protein Rab-5B RAB9A, member RAS oncogene family 201 aa 165 aa 30.9 %
Brugia malayi Hypothetical 65.5 kDa Trp-Asp repeats containing protein F02E8.5 inchromosome X geminin, DNA replication inhibitor 209 aa 176 aa 27.8 %
Brugia malayi steroid hormone receptor vitamin D (1,25- dihydroxyvitamin D3) receptor 427 aa 416 aa 24.5 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Protein kinase c protein 2 0.0107 0.0638 0.0636
Trichomonas vaginalis mitogen-activated protein kinase kinase kinase 3, MAPKKK3, MEKK3, putative 0.0047 0.011 0.0097
Entamoeba histolytica PH domain containing protein kinase, putative 0.0074 0.0346 0.034
Onchocerca volvulus Serine\/threonine kinase homolog 0.1171 1 1
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0068 0.0291 0.0279
Echinococcus granulosus twitchin 0.0127 0.0809 0.0807
Echinococcus granulosus cyclin dependent kinase 0.0119 0.0744 0.0742
Echinococcus multilocularis serine:threonine protein kinase N2 0.0147 0.0988 0.0986
Echinococcus granulosus serine/threonine protein kinase 0.0168 0.1173 0.1171
Plasmodium vivax protein kinase, putative 0.0042 0.0062 0.045
Onchocerca volvulus 0.013 0.0842 0.0842
Schistosoma mansoni protein kinase 0.0234 0.175 0.1748
Trichomonas vaginalis CAMK family protein kinase 0.1171 1 1
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0036 0.0013 0.0006
Loa Loa (eye worm) TK protein kinase 0.0135 0.0885 0.0883
Entamoeba histolytica protein kinase domain containing protein 0.0036 0.0013 0.0006
Brugia malayi Immunoglobulin I-set domain containing protein 0.0044 0.0084 0.0082
Schistosoma mansoni tyrosine kinase 0.0036 0.0013 0.0011
Echinococcus granulosus ephrin type A receptor 4 A 0.0108 0.0646 0.0644
Schistosoma mansoni protein kinase 0.0065 0.027 0.0267
Brugia malayi Protein kinase domain containing protein 0.0036 0.0013 0.0011
Entamoeba histolytica PH domain containing protein kinase, putative 0.0168 0.1173 0.1167
Echinococcus multilocularis casein kinase ii subunit alpha 0.0098 0.0559 0.0557
Schistosoma mansoni roundabout 0.0039 0.0042 0.004
Entamoeba histolytica protein kinase domain containing protein 0.0036 0.0013 0.0006
Loa Loa (eye worm) TK/EPH protein kinase 0.0128 0.082 0.0818
Loa Loa (eye worm) hypothetical protein 0.0136 0.0896 0.0894
Giardia lamblia Kinase, STE STE20 0.0082 0.042 0.0408
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0183 0.1303 0.1301
Trichomonas vaginalis CAMK family protein kinase 0.1171 1 1
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0036 0.0013 0.0006
Schistosoma mansoni protein kinase C mu 0.0038 0.0034 0.0032
Echinococcus granulosus growth factor receptor bound protein 2 0.006 0.0224 0.0222
Brugia malayi protein-tyrosine kinase 0.0135 0.0885 0.0883
Loa Loa (eye worm) TK protein kinase 0.0036 0.0013 0.0011
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0085 0.0444 0.0442
Echinococcus granulosus tyrosine protein kinase Lyn 0.0185 0.132 0.1318
Echinococcus granulosus kinase suppressor of Ras 1 0.0036 0.0013 0.0011
Entamoeba histolytica cysteine surface protein, putative 0.0036 0.0013 0.0006
Echinococcus multilocularis FL cytokine receptor 0.0036 0.0013 0.0011
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0036 0.0013 0.0006
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0183 0.1303 0.1301
Plasmodium falciparum glycogen synthase kinase 3 0.013 0.0842 0.7499
Trichomonas vaginalis CMGC family protein kinase 0.0098 0.0559 0.0547
Echinococcus granulosus atrial natriuretic peptide receptor 1 0.0036 0.0013 0.0011
Loa Loa (eye worm) TK protein kinase 0.0036 0.0013 0.0011
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.013 0.0842 0.084
Echinococcus multilocularis cyclin dependent kinase 5 0.0119 0.0744 0.0742
Echinococcus multilocularis casein kinase I delta 0.0065 0.027 0.0267
Trichomonas vaginalis AGC family protein kinase 0.0147 0.0988 0.0976
Onchocerca volvulus 0.0069 0.0305 0.0305
Schistosoma mansoni serine/threonine protein kinase 0.0147 0.099 0.0988
Brugia malayi Protein kinase domain containing protein 0.0197 0.1433 0.1431
Entamoeba histolytica protein kinase domain containing protein 0.0036 0.0013 0.0006
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0119 0.0744 0.3328
Loa Loa (eye worm) TK protein kinase 0.0036 0.0013 0.0011
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0118 0.0106
Loa Loa (eye worm) hypothetical protein 0.0365 0.2906 0.2905
Schistosoma mansoni serine/threonine protein kinase 0.0036 0.0013 0.0011
Entamoeba histolytica serine/threonine kinase, putative 0.0036 0.0013 0.0006
Entamoeba histolytica protein kinase, putative 0.0147 0.0988 0.0982
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0283 0.2183 0.2182
Echinococcus granulosus contactin 0.0042 0.0066 0.0064
Brugia malayi Immunoglobulin I-set domain containing protein 0.0042 0.0066 0.0064
Entamoeba histolytica hypothetical protein 0.0036 0.0015 0.0009
Loa Loa (eye worm) variant SH3 domain-containing protein 0.006 0.0224 0.0222
Brugia malayi Protein kinase domain containing protein 0.0292 0.2265 0.2264
Brugia malayi Immunoglobulin I-set domain containing protein 0.0039 0.0042 0.004
Schistosoma mansoni tyrosine kinase 0.0036 0.0013 0.0011
Echinococcus granulosus rho-associated protein kinase 1 0.0351 0.2785 0.2784
Loa Loa (eye worm) TKL/MLK/TAK1 protein kinase 0.0036 0.0013 0.0011
Echinococcus granulosus tyrosine protein kinase Src42A 0.0099 0.0568 0.0566
Echinococcus multilocularis telomerase reverse transcriptase subunit 0.0045 0.0088 0.0086
Trichomonas vaginalis CMGC family protein kinase 0.008 0.0397 0.0385
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0069 0.0305 0.0299
Trichomonas vaginalis AGC family protein kinase 0.0147 0.0988 0.0976
Brugia malayi Protein kinase domain containing protein 0.0036 0.0013 0.0011
Echinococcus multilocularis serine:threonine protein kinase 0.0114 0.0698 0.0696
Trichomonas vaginalis CMGC family protein kinase 0.0098 0.0559 0.0547
Echinococcus granulosus serine:threonine protein kinase 3 0.0274 0.211 0.2108
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0162 0.1121 0.1119
Onchocerca volvulus 0.0036 0.0013 0.0013
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0118 0.0106
Trypanosoma cruzi cdc2-related kinase 1 0.0119 0.0744 0.0733
Giardia lamblia Kinase, CAMK CAMKL 0.0048 0.0118 0.0106
Brugia malayi Protein kinase domain containing protein 0.0036 0.0013 0.0011
Schistosoma mansoni ephrin receptor 0.0039 0.0037 0.0034
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0065 0.027 0.0267
Loa Loa (eye worm) hypothetical protein 0.013 0.0842 0.084
Loa Loa (eye worm) TK/FER protein kinase 0.0069 0.0305 0.0303
Giardia lamblia Kinase, CMGC CDK 0.0119 0.0744 0.0733
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0036 0.0013 0.0011
Schistosoma mansoni protein kinase 0.0058 0.0205 0.0203
Entamoeba histolytica protein kinase domain containing protein 0.0036 0.0013 0.0006
Loa Loa (eye worm) serine/threonine protein kinase 0.0036 0.0013 0.0011
Plasmodium falciparum calcium-dependent protein kinase 3 0.0048 0.0119 0.0961
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.008 0.0397 0.0395
Loa Loa (eye worm) hypothetical protein 0.0037 0.0018 0.0016
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0068 0.0291 0.0289
Trichomonas vaginalis CMGC family protein kinase 0.0119 0.0744 0.0733
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0068 0.0291 0.0279
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.0429 0.3469 0.3467
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0036 0.0013 0.0011
Schistosoma mansoni serine/threonine protein kinase 0.0119 0.0744 0.0742
Echinococcus multilocularis titin 0.0044 0.0084 0.0082
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0118 0.0106
Loa Loa (eye worm) hypothetical protein 0.0124 0.0791 0.0789
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0069 0.0305 0.0303
Brugia malayi Casein kinase II, alpha chain 0.0098 0.0559 0.0557
Schistosoma mansoni vesicular amine transporter 0.0085 0.0444 0.0442
Echinococcus granulosus PAK box P21 Rho binding 0.0035 0.0006 0.0004
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0147 0.0988 0.0986
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0162 0.1121 0.1119
Schistosoma mansoni tyrosine kinase 0.0036 0.0013 0.0011
Schistosoma mansoni serine/threonine protein kinase 0.0283 0.2183 0.2182
Entamoeba histolytica tyrosine kinase, putative 0.0036 0.0013 0.0006
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.013 0.0842 0.3772
Schistosoma mansoni hypothetical protein 0.0038 0.0034 0.0032
Entamoeba histolytica hypothetical protein 0.0043 0.0078 0.0072
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.008 0.0397 0.0385
Onchocerca volvulus 0.0036 0.0013 0.0013
Echinococcus multilocularis cyclin dependent kinase 0.0119 0.0744 0.0742
Onchocerca volvulus 0.0546 0.4501 0.4501
Loa Loa (eye worm) hypothetical protein 0.0048 0.0118 0.0116
Schistosoma mansoni atypical protein kinase C 0.0285 0.2207 0.2205
Echinococcus multilocularis PAK box P21 Rho binding 0.0035 0.0006 0.0004
Brugia malayi cell division control protein 2 homolog 0.0119 0.0744 0.0742
Echinococcus granulosus casein kinase I alpha 0.0065 0.027 0.0267
Brugia malayi casein kinase 1, delta 0.0065 0.027 0.0267
Entamoeba histolytica receptor protein kinase, putative 0.0036 0.0013 0.0006
Entamoeba histolytica hypothetical protein 0.0036 0.0013 0.0006
Schistosoma mansoni protein kinase 0.0036 0.0013 0.0011
Loa Loa (eye worm) hypothetical protein 0.0039 0.0042 0.004
Loa Loa (eye worm) hypothetical protein 0.0092 0.0503 0.0501
Schistosoma mansoni serine/threonine protein kinase 0.0048 0.0118 0.0116
Giardia lamblia Kinase, AGC PKA 0.0068 0.0291 0.0279
Schistosoma mansoni tyrosine kinase 0.0036 0.0013 0.0011
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0153 0.1041 0.1039
Trypanosoma brucei rac serine-threonine kinase, putative 0.0292 0.2265 0.2256
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0149 0.1008 0.1003
Echinococcus granulosus roundabout 2 0.0042 0.0066 0.0064
Entamoeba histolytica protein kinase, putative 0.0036 0.0013 0.0006
Entamoeba histolytica protein kinase, putative 0.0064 0.026 0.0254
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0148 0.1002 0.1
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0048 0.0119 0.0961
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0036 0.0013 0.0011
Loa Loa (eye worm) transcription factor SMAD2 0.0144 0.0964 0.0962
Brugia malayi Immunoglobulin I-set domain containing protein 0.0039 0.0042 0.004
Schistosoma mansoni tyrosine kinase 0.0259 0.1974 0.1972
Entamoeba histolytica protein kinase, putative 0.0036 0.0013 0.0006
Loa Loa (eye worm) hypothetical protein 0.0039 0.0042 0.004
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0068 0.0291 0.0289
Trypanosoma cruzi cdc2-related kinase 3 0.0119 0.0744 0.0733
Loa Loa (eye worm) sex muscle abnormal protein 5 0.006 0.0224 0.0222
Loa Loa (eye worm) protein kinase domain-containing protein 0.0036 0.0013 0.0011
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0044 0.0084 0.0082
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0162 0.1121 0.1119
Echinococcus granulosus insulin receptor 0.0489 0.3994 0.3993
Loa Loa (eye worm) TK/FER protein kinase 0.0036 0.0013 0.0011
Echinococcus multilocularis protein kinase c iota type 0.0279 0.2146 0.2145
Onchocerca volvulus 0.0043 0.007 0.007
Echinococcus multilocularis protein kinase 0.0036 0.0013 0.0011
Schistosoma mansoni diacylglycerol kinase theta 0.0038 0.0034 0.0032
Loa Loa (eye worm) hypothetical protein 0.0234 0.1755 0.1753
Echinococcus granulosus tyrosine protein kinase Src64B 0.0162 0.1121 0.1119
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0065 0.027 0.0257
Loa Loa (eye worm) hypothetical protein 0.0036 0.0013 0.0011
Entamoeba histolytica tyrosin kinase, putative 0.0036 0.0013 0.0006
Brugia malayi Immunoglobulin I-set domain containing protein 0.0088 0.0468 0.0466
Trichomonas vaginalis CAMK family protein kinase 0.0563 0.4647 0.464
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0162 0.1121 0.1119
Schistosoma mansoni tyrosine kinase 0.0036 0.0013 0.0011
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0036 0.0013 0.0011
Entamoeba histolytica hypothetical protein 0.0043 0.0078 0.0072
Entamoeba histolytica hypothetical protein 0.0036 0.0013 0.0006
Loa Loa (eye worm) TK/FER protein kinase 0.0036 0.0013 0.0011
Loa Loa (eye worm) hypothetical protein 0.0038 0.0034 0.0032
Brugia malayi integrin-linked kinase 0.0036 0.0013 0.0011
Loa Loa (eye worm) hypothetical protein 0.0072 0.0329 0.0327
Leishmania major casein kinase II, putative 0.0098 0.0559 0.0547
Brugia malayi Protein kinase domain containing protein 0.0036 0.0013 0.0011
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0068 0.0291 0.0279
Loa Loa (eye worm) hypothetical protein 0.0036 0.0013 0.0011
Entamoeba histolytica protein kinase, putative 0.0036 0.0013 0.0006
Echinococcus multilocularis serine:threonine protein kinase Chk2 0.0065 0.027 0.0268
Trichomonas vaginalis CMGC family protein kinase 0.008 0.0397 0.0385
Schistosoma mansoni serine/threonine protein kinase 0.0048 0.0119 0.0117
Trichomonas vaginalis AGC family protein kinase 0.0147 0.0988 0.0976
Brugia malayi C-terminal src kinase protein 1 0.0036 0.0013 0.0011
Brugia malayi p70 ribosomal S6 kinase beta 0.0286 0.2211 0.2209
Trichomonas vaginalis STE family protein kinase 0.0081 0.0407 0.0394
Entamoeba histolytica hypothetical protein 0.0036 0.0013 0.0006
Plasmodium vivax protein kinase Crk2 0.0119 0.0744 0.6616
Echinococcus multilocularis casein kinase I delta 0.0065 0.027 0.0267
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0153 0.1041 0.1039
Entamoeba histolytica cell division protein kinase 2, putative 0.0119 0.0744 0.0739
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0048 0.0119 0.0117
Entamoeba histolytica protein kinase domain containing protein 0.0036 0.0013 0.0006
Loa Loa (eye worm) SRC-1 0.0162 0.1121 0.1119
Echinococcus granulosus tyrosine protein kinase 0.0036 0.0013 0.0011
Echinococcus granulosus tyrosine protein kinase Fyn 0.0162 0.1121 0.1119
Trichomonas vaginalis AGC family protein kinase 0.0149 0.1008 0.0997
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0149 0.1008 0.1003
Trichomonas vaginalis CMGC family protein kinase 0.0098 0.0559 0.0547
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0069 0.0305 0.0303
Echinococcus multilocularis protein kinase c epsilon type 0.0187 0.1339 0.1337
Echinococcus granulosus c src tyrosine kinase 0.0096 0.0541 0.0539
Brugia malayi Protein kinase domain containing protein 0.0202 0.1476 0.1474
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0085 0.0444 0.0442
Entamoeba histolytica hypothetical protein, conserved 0.0036 0.0013 0.0006
Onchocerca volvulus Heat shock factor protein 2 homolog 0.012 0.0749 0.0749
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.008 0.0397 0.0385
Echinococcus granulosus peroxidasin 0.004 0.0045 0.0042
Onchocerca volvulus Tyrosine kinase homolog 0.0601 0.4983 0.4983
Entamoeba histolytica protein kinase, putative 0.0058 0.0205 0.0199
Onchocerca volvulus 0.0036 0.0013 0.0013
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0162 0.1121 0.1119
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0149 0.1008 0.1006
Entamoeba histolytica protein kinase, putative 0.0102 0.0593 0.0587
Entamoeba histolytica protein kinase, putative 0.0077 0.0375 0.0369
Entamoeba histolytica serine/threonine kinase, putative 0.0036 0.0013 0.0006
Echinococcus granulosus retinal guanylyl cyclase 2 0.0036 0.0013 0.0011
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.008 0.0397 0.0385
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0036 0.0013 0.0006
Entamoeba histolytica serine/threonine kinase, putative 0.0036 0.0013 0.0006
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.008 0.0397 0.0385
Echinococcus granulosus Rac GTPase activating protein 1 0.0038 0.0034 0.0032
Brugia malayi Immunoglobulin I-set domain containing protein 0.0042 0.0066 0.0064
Schistosoma mansoni serine/threonine protein kinase 0.0047 0.011 0.0108
Echinococcus granulosus tyrosine protein kinase csk 0.0036 0.0013 0.0011
Brugia malayi Protein kinase domain containing protein 0.0069 0.0305 0.0303
Echinococcus granulosus glycogen synthase kinase 3 beta 0.013 0.0842 0.084
Echinococcus granulosus tyrosine kinase 0.0069 0.0305 0.0303
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.0247 0.1865 0.1863
Brugia malayi Guanylyl cyclase protein 23 0.0036 0.0013 0.0011
Echinococcus granulosus serine:threonine protein kinase Chk2 0.0065 0.027 0.0268
Schistosoma mansoni kinase 0.0757 0.6355 0.6354
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0106 0.0625 0.0623
Schistosoma mansoni protein kinase 0.0059 0.0212 0.021
Echinococcus granulosus 3'partial|retinal guanylyl cyclase 2 0.0036 0.0013 0.0011
Trichomonas vaginalis CMGC family protein kinase 0.013 0.0842 0.083
Echinococcus multilocularis NCK adaptor protein 0.006 0.0224 0.0222
Entamoeba histolytica tyrosine kinase, putative 0.0036 0.0013 0.0006
Loa Loa (eye worm) hypothetical protein 0.0161 0.1116 0.1114
Schistosoma mansoni protein kinase 0.0036 0.0013 0.0011
Echinococcus multilocularis tyrosine protein kinase 0.0036 0.0013 0.0011
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0302 0.2356 0.2355
Entamoeba histolytica tyrosine kinase, putative 0.0036 0.0013 0.0006
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0162 0.1118 1
Entamoeba histolytica protein kinase, putative 0.0292 0.2265 0.2261
Brugia malayi Cam kinase protein 1 0.0048 0.0119 0.0117
Schistosoma mansoni hypothetical protein 0.0205 0.1496 0.1494
Toxoplasma gondii histone kinase SNF1, putative 0.0048 0.0118 0.0481
Echinococcus granulosus protein kinase c epsilon type 0.0187 0.1339 0.1337
Brugia malayi Protein kinase domain containing protein 0.0077 0.0375 0.0373
Echinococcus multilocularis roundabout 2 0.0042 0.0066 0.0064
Schistosoma mansoni protein kinase 0.0036 0.0013 0.0011
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0149 0.1008 0.1006
Schistosoma mansoni hypothetical protein 0.0036 0.0013 0.0011
Schistosoma mansoni tyrosine kinase 0.0437 0.3543 0.3541
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0118 0.0106
Schistosoma mansoni nephrin 0.0107 0.0633 0.0631
Loa Loa (eye worm) hypothetical protein 0.004 0.0045 0.0042
Entamoeba histolytica heat shock transcription factor, putative 0.012 0.0749 0.0743
Schistosoma mansoni wiskott-aldrich syndrome protein 0.0035 0.0006 0.0004
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0128 0.082 0.0818
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0048 0.0119 0.0117
Trypanosoma cruzi polo-like protein kinase, putative 0.1171 1 1
Brugia malayi Protein kinase domain containing protein 0.0069 0.0305 0.0303
Onchocerca volvulus 0.0036 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0039 0.0042 0.004
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.0429 0.3469 0.3467
Echinococcus granulosus retinal guanylyl cyclase 2 0.0036 0.0013 0.0011
Loa Loa (eye worm) hypothetical protein 0.0036 0.0013 0.0011
Echinococcus granulosus aurora kinase A 0.0149 0.1008 0.1006
Echinococcus granulosus neuropeptide s receptor 0.0558 0.4608 0.4607
Schistosoma mansoni tyrosine kinase 0.0096 0.0541 0.0539
Echinococcus multilocularis epidermal growth factor receptor 0.0437 0.3543 0.3541
Brugia malayi Immunoglobulin I-set domain containing protein 0.0036 0.0016 0.0014
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0202 0.1476 0.1474
Loa Loa (eye worm) hypothetical protein 0.0088 0.0468 0.0466
Toxoplasma gondii AGC kinase 0.0068 0.0291 0.1267
Brugia malayi Immunoglobulin I-set domain containing protein 0.0688 0.5747 0.5746
Schistosoma mansoni serine/threonine protein kinase 0.0231 0.1731 0.1729
Toxoplasma gondii CMGC kinase, CK2 family 0.0098 0.0559 0.2487
Onchocerca volvulus 0.0069 0.0305 0.0305
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0162 0.1121 0.1119
Brugia malayi SH2 domain containing protein 0.0069 0.0305 0.0303
Entamoeba histolytica protein kinase domain containing protein 0.0036 0.0013 0.0006
Echinococcus granulosus MAP kinase activated protein kinase 2 0.0429 0.3469 0.3467
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0059 0.0212 0.0199
Echinococcus multilocularis casein kinase I alpha 0.0065 0.027 0.0267
Brugia malayi Protein kinase domain containing protein 0.1045 0.8887 0.8887
Schistosoma mansoni serine/threonine protein kinase 0.0202 0.1476 0.1474
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0036 0.0013 0.0011
Trichomonas vaginalis AGC family protein kinase 0.0077 0.0375 0.0363
Brugia malayi SRC-1 0.0162 0.1121 0.1119
Echinococcus granulosus geminin 0.0205 0.1496 0.1494
Entamoeba histolytica protein kinase, putative 0.0036 0.0013 0.0006
Trichomonas vaginalis CK1 family protein kinase 0.0065 0.027 0.0257
Loa Loa (eye worm) hypothetical protein 0.0156 0.1069 0.1067
Entamoeba histolytica protein kinase, putative 0.0036 0.0013 0.0006
Loa Loa (eye worm) hypothetical protein 0.0039 0.0042 0.004
Schistosoma mansoni vav2 0.0078 0.0381 0.0379
Echinococcus granulosus tyrosine protein kinase Src42A 0.0162 0.1121 0.1119
Trichomonas vaginalis AGC family protein kinase 0.0292 0.2265 0.2256
Loa Loa (eye worm) AUR protein kinase 0.0149 0.1008 0.1006
Loa Loa (eye worm) AUR protein kinase 0.0149 0.1008 0.1006
Schistosoma mansoni tyrosine kinase 0.0036 0.0013 0.0011
Schistosoma mansoni unc-13 (munc13) 0.0042 0.0067 0.0065
Echinococcus multilocularis mitogen activated protein kinase 11 0.0165 0.1143 0.1141
Entamoeba histolytica tyrosine kinase, putative 0.0036 0.0013 0.0006
Echinococcus multilocularis tyrosine protein kinase Fes:Fps 0.0036 0.0013 0.0011
Schistosoma mansoni cell adhesion molecule 0.0042 0.0066 0.0064
Trichomonas vaginalis CAMK family protein kinase 0.0114 0.0698 0.0686
Loa Loa (eye worm) hypothetical protein 0.0068 0.0291 0.0289
Schistosoma mansoni tyrosine kinase 0.0671 0.5602 0.5601
Entamoeba histolytica protein kinase, putative 0.0082 0.042 0.0414
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0036 0.0013 0.0006
Trichomonas vaginalis CMGC family protein kinase 0.0098 0.0559 0.0547
Schistosoma mansoni serine/threonine protein kinase 0.0098 0.0559 0.0557
Echinococcus multilocularis tyrosine protein kinase csk 0.0036 0.0013 0.0011
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0098 0.0559 0.4944
Loa Loa (eye worm) RGC/RGC protein kinase 0.0036 0.0013 0.0011
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.0048 0.0118 0.0106
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0042 0.0066 0.0064
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0036 0.0013 0.0011
Schistosoma mansoni protein kinase 0.0149 0.1008 0.1006
Loa Loa (eye worm) hypothetical protein 0.0038 0.0034 0.0032
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0048 0.0119 0.0961
Schistosoma mansoni neuroglian 0.0042 0.0066 0.0064
Echinococcus granulosus serine:threonine kinase SAD 1 0.0048 0.0118 0.0116
Echinococcus granulosus tyrosine protein kinase ABL1 0.0302 0.2356 0.2355
Trichomonas vaginalis CMGC family protein kinase 0.0098 0.0559 0.0547
Loa Loa (eye worm) TK protein kinase 0.0036 0.0013 0.0011
Schistosoma mansoni protein kinase 0.0048 0.0119 0.0117
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0065 0.027 0.0267
Entamoeba histolytica protein kinase, putative 0.0036 0.0013 0.0006
Echinococcus granulosus mitogen activated protein kinase 0.008 0.0397 0.0395
Echinococcus granulosus neuropeptide receptor A26 0.0558 0.4608 0.4607
Echinococcus granulosus casein kinase I alpha 0.0065 0.027 0.0267
Loa Loa (eye worm) hypothetical protein 0.0069 0.0301 0.0299
Entamoeba histolytica heat shock transcription factor, putative 0.012 0.0749 0.0743
Echinococcus multilocularis Diacylglycerol kinase theta 0.0038 0.0034 0.0032
Entamoeba histolytica protein kinase, putative 0.0036 0.0013 0.0006
Loa Loa (eye worm) hypothetical protein 0.0036 0.0013 0.0011
Entamoeba histolytica tyrosin kinase, putative 0.004 0.0044 0.0038
Trichomonas vaginalis CAMK family protein kinase 0.1171 1 1
Brugia malayi SH2 domain containing protein 0.0069 0.0305 0.0303
Loa Loa (eye worm) TK/ACK protein kinase 0.0036 0.0013 0.0011
Schistosoma mansoni serine/threonine protein kinase 0.0211 0.1555 0.1553
Loa Loa (eye worm) hypothetical protein 0.0036 0.0013 0.0011
Brugia malayi P21-Rho-binding domain containing protein 0.0035 0.0006 0.0004
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0283 0.2183 0.2182
Loa Loa (eye worm) hypothetical protein 0.0097 0.0545 0.0543
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0048 0.0119 0.0484
Schistosoma mansoni tyrosine kinase 0.0219 0.1624 0.1622
Onchocerca volvulus 0.0065 0.027 0.027
Echinococcus granulosus roundabout 2 0.0042 0.0066 0.0064
Loa Loa (eye worm) TK protein kinase 0.0102 0.0593 0.0591
Loa Loa (eye worm) TK/RYK protein kinase 0.0036 0.0013 0.0011
Loa Loa (eye worm) hypothetical protein 0.0036 0.0013 0.0011
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0048 0.0119 0.0117
Brugia malayi Raf kinase 0.0036 0.0013 0.0011
Entamoeba histolytica protein kinase domain containing protein 0.0036 0.0013 0.0006
Giardia lamblia Kinase, CMGC CDK 0.0119 0.0744 0.0733
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0123 0.0778 0.0767
Entamoeba histolytica protein kinase, putative 0.013 0.0842 0.0836
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0119 0.0106
Giardia lamblia Kinase, PLK 0.1171 1 1
Loa Loa (eye worm) AGC/PKN protein kinase 0.0147 0.0988 0.0986
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0068 0.0291 0.0289
Loa Loa (eye worm) hypothetical protein 0.0085 0.0444 0.0442
Trypanosoma brucei protein kinase, putative 0.0059 0.0212 0.0199
Schistosoma mansoni hypothetical protein 0.0035 0.0006 0.0004
Plasmodium falciparum serine/threonine protein kinase KIN 0.0048 0.0118 0.0957
Leishmania major protein kinase, putative 0.0059 0.0212 0.0199
Schistosoma mansoni serine/threonine protein kinase 0.0077 0.0375 0.0373
Onchocerca volvulus 0.0069 0.0305 0.0305
Echinococcus granulosus roundabout 2 0.0127 0.0814 0.0812
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0068 0.0291 0.2518
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0162 0.1118 0.1117
Entamoeba histolytica protein kinase domain containing protein 0.0036 0.0013 0.0006
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0039 0.0042 0.004
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0036 0.0013 0.0006
Onchocerca volvulus 0.004 0.0047 0.0047
Entamoeba histolytica ankyrin repeat protein 0.0036 0.0013 0.0006
Echinococcus multilocularis dual specificity 0.0123 0.0778 0.0776
Entamoeba histolytica hypothetical protein 0.0038 0.0034 0.0028
Echinococcus multilocularis receptor type guanylyl cyclase 0.0036 0.0013 0.0011
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0202 0.1476 0.1476
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0048 0.0119 0.0117
Echinococcus granulosus protein kinase c iota type 0.0279 0.2146 0.2145
Brugia malayi Furin-like cysteine rich region family protein 0.0671 0.5602 0.5601
Schistosoma mansoni diacylglycerol kinase theta 0.0038 0.0034 0.0032
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0038 0.0034 0.0032
Schistosoma mansoni protein kinase C 0.004 0.0047 0.0045
Entamoeba histolytica hypothetical protein 0.0036 0.0013 0.0006
Loa Loa (eye worm) hypothetical protein 0.006 0.0221 0.0219
Schistosoma mansoni serine/threonine protein kinase 0.0065 0.027 0.0267
Schistosoma mansoni adapter molecule crk 0.006 0.0224 0.0222
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0183 0.1303 0.1301
Echinococcus multilocularis activated cdc42 kinase 1 0.0036 0.0013 0.0011
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0036 0.0013 0.0011
Schistosoma mansoni serine/threonine protein kinase 0.0044 0.0084 0.0082
Brugia malayi protein kinase C II. 0.0187 0.1339 0.1337
Echinococcus multilocularis Immunoglobulin 0.0085 0.0444 0.0442
Echinococcus multilocularis tyrosine kinase 0.0069 0.0305 0.0303
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0156 0.1072 0.107
Brugia malayi Variant SH3 domain containing protein 0.006 0.0224 0.0222
Loa Loa (eye worm) hypothetical protein 0.0125 0.0797 0.0795
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0081 0.0407 0.0394
Echinococcus granulosus dual specificity 0.0123 0.0778 0.0776
Plasmodium falciparum NIMA related kinase 1 0.0139 0.0916 0.8168
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0036 0.0013 0.0006
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0221 0.0208
Brugia malayi Protein kinase domain containing protein 0.0302 0.2353 0.2351
Brugia malayi RhoGAP domain containing protein 0.0038 0.0034 0.0032
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.013 0.0842 0.083
Plasmodium falciparum casein kinase 1 0.0065 0.027 0.2323
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0119 0.0744 0.0733
Echinococcus multilocularis atrial natriuretic peptide receptor 1 0.0036 0.0013 0.0011
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0036 0.0013 0.0013
Onchocerca volvulus 0.0036 0.0013 0.0013
Entamoeba histolytica protein kinase domain containing protein 0.0149 0.1008 0.1003
Schistosoma mansoni serine/threonine protein kinase 0.0156 0.1072 0.107
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0139 0.0916 0.4108
Entamoeba histolytica protein kinase domain containing protein 0.0036 0.0013 0.0006
Entamoeba histolytica PH domain containing protein kinase, putative 0.0168 0.1173 0.1167
Echinococcus multilocularis hemicentin 1 0.0039 0.0042 0.004
Schistosoma mansoni serine/threonine protein kinase 0.0429 0.3469 0.3467
Entamoeba histolytica protein kinase, putative 0.0292 0.2265 0.2261
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0048 0.0118 0.0116
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0048 0.0118 0.0116
Entamoeba histolytica diacylglycerol kinase, putative 0.0038 0.0034 0.0028
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0072 0.0327 0.0324
Entamoeba histolytica protein kinase domain containing protein 0.0123 0.0778 0.0773
Trypanosoma cruzi polo-like protein kinase, putative 0.1171 1 1
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0072 0.0327 0.0324
Loa Loa (eye worm) TK/ABL protein kinase 0.0302 0.2356 0.2355
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0119 0.0744 0.0742
Brugia malayi hypothetical protein 0.0365 0.2906 0.2905
Brugia malayi MAP kinase sur-1 0.008 0.0397 0.0395
Echinococcus granulosus tyrosine protein kinase Blk 0.0135 0.0885 0.0883
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0119 0.0744 0.0733
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0082 0.042 0.0418
Schistosoma mansoni tyrosine protein kinase 0.0036 0.0013 0.0011
Brugia malayi Hr1 repeat family protein 0.0147 0.0988 0.0986
Brugia malayi serine/threonine kinase 12 0.0149 0.1008 0.1006
Entamoeba histolytica casein kinase 1, putative 0.0065 0.027 0.0264
Trichomonas vaginalis CK1 family protein kinase 0.0065 0.027 0.0257
Schistosoma mansoni protein kinase 0.0234 0.175 0.1748
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0162 0.1121 0.1119
Loa Loa (eye worm) CMGC/GSK protein kinase 0.013 0.0842 0.084
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0123 0.0778 0.0776
Plasmodium falciparum calcium-dependent protein kinase 2 0.0048 0.0119 0.0961
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0036 0.0013 0.0006
Schistosoma mansoni tyrosine kinase 0.0036 0.0013 0.0011
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0259 0.1974 0.1972
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0082 0.042 0.0418
Brugia malayi diacylglycerol kinase 0.0038 0.0034 0.0032
Trichomonas vaginalis STE family protein kinase 0.0058 0.0205 0.0193
Schistosoma mansoni serine/threonine-protein kinase 0.0168 0.1173 0.1171
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0491 0.4018 0.4016
Echinococcus granulosus mitogen activated protein kinase 3 0.008 0.0397 0.0395
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0118 0.0106
Giardia lamblia Kinase, CMGC GSK 0.013 0.0842 0.083
Loa Loa (eye worm) Ras association domain family 1 isoform A 0.0038 0.0034 0.0032
Entamoeba histolytica protein kinase 2, putative 0.0162 0.1118 0.1113
Trichomonas vaginalis AGC family protein kinase 0.0139 0.0916 0.0904
Trichomonas vaginalis AGC family protein kinase 0.0292 0.2265 0.2256
Brugia malayi STE20-like kinase MST 0.0274 0.211 0.2108
Entamoeba histolytica protein kinase, putative 0.0149 0.1008 0.1003
Echinococcus multilocularis casein kinase I alpha 0.0065 0.027 0.0267
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.0114 0.0698 0.0696
Echinococcus multilocularis roundabout 2 0.0127 0.0814 0.0812
Onchocerca volvulus 0.0044 0.0084 0.0084
Echinococcus granulosus activated cdc42 kinase 1 0.0036 0.0013 0.0011
Echinococcus multilocularis tyrosine protein kinase shark 0.0069 0.0305 0.0303
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0036 0.0013 0.0006
Brugia malayi Protein kinase domain 0.0082 0.042 0.0418
Loa Loa (eye worm) hypothetical protein 0.012 0.0749 0.0747
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0042 0.0066 0.0064
Trichomonas vaginalis CMGC family protein kinase 0.008 0.0397 0.0385
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0123 0.0778 0.0767
Trichomonas vaginalis AGC family protein kinase 0.0077 0.0375 0.0363
Echinococcus multilocularis myosin iiia 0.0081 0.0407 0.0405
Entamoeba histolytica protein kinase, putative 0.0036 0.0013 0.0006
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0124 0.0788 0.0777
Trypanosoma cruzi Protein kinase B 0.0168 0.1173 0.1162
Echinococcus granulosus casein kinase I alpha 0.0065 0.027 0.0267
Echinococcus granulosus casein kinase ii subunit alpha 0.0098 0.0559 0.0557
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0162 0.1118 1
Echinococcus multilocularis C2 calcium dependent membrane targeting 0.004 0.0047 0.0045
Brugia malayi Variant SH3 domain containing protein 0.006 0.0224 0.0222
Entamoeba histolytica tyrosine kinase, putative 0.0036 0.0013 0.0006
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0036 0.0013 0.0011
Brugia malayi Cytochrome P450 family protein 0.0063 0.0252 0.025
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0118 0.0106
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0036 0.0013 0.0011
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.0036 0.0013 0.0011
Onchocerca volvulus Tyrosine kinase receptor Cad96Ca homolog 0.0036 0.0013 0.0013
Brugia malayi phosphoinositide-dependent protein kinase I 0.0077 0.0375 0.0373
Brugia malayi Protein kinase domain containing protein 0.0036 0.0013 0.0011
Echinococcus multilocularis mitogen activated protein kinase 11 0.0165 0.1143 0.1141
Brugia malayi Tyrosine-protein kinase abl-1 0.0144 0.0963 0.0961
Echinococcus multilocularis calcium activated potassium channel 0.0091 0.05 0.0498
Schistosoma mansoni tyrosine kinase 0.0036 0.0013 0.0011
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0048 0.0119 0.0484
Entamoeba histolytica hypothetical protein 0.0036 0.0015 0.0009
Onchocerca volvulus 0.0036 0.0013 0.0013
Entamoeba histolytica protein kinase domain containing protein 0.013 0.0842 0.0836
Echinococcus multilocularis hypothetical protein 0.0069 0.0301 0.0299
Plasmodium vivax unspecified product 0.0098 0.0559 0.4944
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0147 0.0988 0.0986
Onchocerca volvulus 0.0156 0.1069 0.1069
Entamoeba histolytica protein kinase domain containing protein 0.0036 0.0013 0.0006
Echinococcus multilocularis serine:threonine protein kinase N2 0.0147 0.0988 0.0986
Entamoeba histolytica protein kinase , putative 0.0149 0.1008 0.1003
Brugia malayi Protein kinase domain containing protein 0.0036 0.0013 0.0011
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0036 0.0013 0.0006
Echinococcus multilocularis tyrosine protein kinase csk 0.0036 0.0013 0.0011
Entamoeba histolytica protein kinase domain containing protein 0.0036 0.0013 0.0006
Echinococcus granulosus NCK adaptor protein 0.006 0.0224 0.0222
Schistosoma mansoni titin 0.0039 0.0042 0.004
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0059 0.0212 0.0199
Echinococcus multilocularis cyclin dependent kinase 1 0.0119 0.0744 0.0742
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0346 0.2743 0.2742
Brugia malayi protein kinase C3,putative 0.0154 0.1054 0.1052
Echinococcus multilocularis unc 13 (munc13) 0.004 0.0047 0.0045
Brugia malayi Protein kinase domain containing protein 0.0123 0.0778 0.0776
Brugia malayi p21/Cdc42/Rac1-activated kinase 0.0047 0.011 0.0108
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0036 0.0013 0.0011
Echinococcus multilocularis mitogen activated protein kinase 14 0.0165 0.1143 0.1141
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0162 0.1121 0.1119
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.0036 0.0013 0.0011
Entamoeba histolytica tyrosine kinase, putative 0.0036 0.0013 0.0006
Echinococcus multilocularis tyrosine protein kinase Srms 0.0135 0.0885 0.0883
Brugia malayi hypothetical protein 0.0069 0.0305 0.0303
Echinococcus multilocularis tyrosine protein kinase csk 0.0036 0.0013 0.0011
Plasmodium falciparum calcium-dependent protein kinase 1 0.0048 0.0119 0.0961
Loa Loa (eye worm) TK/FER protein kinase 0.0036 0.0013 0.0011
Loa Loa (eye worm) CAMK protein kinase 0.0044 0.0084 0.0082
Echinococcus granulosus protein tyrosine kinase 0.0036 0.0013 0.0011
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0118 0.0106
Loa Loa (eye worm) RasGEF domain-containing protein 0.0038 0.0034 0.0032
Entamoeba histolytica protein kinase domain containing protein 0.0036 0.0013 0.0006
Echinococcus granulosus Protein kinase C brain isozyme 0.0231 0.1731 0.1729
Schistosoma mansoni tyrosine kinase 0.0401 0.3226 0.3225
Loa Loa (eye worm) AGC/NDR protein kinase 0.0147 0.0988 0.0986
Brugia malayi Prion-like- 0.0039 0.0042 0.004
Brugia malayi hypothetical protein 0.0036 0.0013 0.0011
Brugia malayi hypothetical protein 0.0036 0.0013 0.0011
Schistosoma mansoni serine/threonine protein kinase 0.1171 1 1
Schistosoma mansoni unc-13 (munc13) 0.004 0.0047 0.0045
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.008 0.0397 0.175
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0246 0.186 0.1859
Loa Loa (eye worm) TK/KIN6 protein kinase 0.0036 0.0013 0.0011
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0119 0.0744 0.0742
Echinococcus multilocularis death associated protein kinase 1 0.094 0.7961 0.7961
Entamoeba histolytica protein kinase domain containing protein 0.0036 0.0013 0.0006
Loa Loa (eye worm) hypothetical protein 0.004 0.0047 0.0045
Echinococcus multilocularis roundabout 2 0.0042 0.0066 0.0064
Trichomonas vaginalis CAMK family protein kinase 0.0091 0.05 0.0488
Trichomonas vaginalis CMGC family protein kinase 0.0098 0.0559 0.0547
Schistosoma mansoni serine/threonine protein kinase 0.0091 0.05 0.0498
Entamoeba histolytica tyrosine kinase, putative 0.0036 0.0013 0.0006
Brugia malayi Immunoglobulin I-set domain containing protein 0.0042 0.0066 0.0064
Giardia lamblia Aurora kinase 0.0149 0.1008 0.0997
Entamoeba histolytica tyrosine kinase, putative 0.0036 0.0013 0.0006
Schistosoma mansoni tyrosine kinase 0.0036 0.0013 0.0011
Loa Loa (eye worm) hypothetical protein 0.0195 0.1407 0.1406
Toxoplasma gondii aurora kinase 0.0149 0.1008 0.4529
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0202 0.1476 0.1474
Brugia malayi Protein kinase domain containing protein 0.0119 0.0744 0.0742
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0162 0.1121 0.1119
Loa Loa (eye worm) RGC/RGC protein kinase 0.0036 0.0013 0.0011
Echinococcus granulosus neural Wiskott Aldrich syndrome protein 0.0035 0.0006 0.0004
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0119 0.0744 0.0742
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0147 0.0988 0.0986
Trypanosoma cruzi aurora B kinase, putative 0.0149 0.1008 0.0997
Schistosoma mansoni rac gtpase activating protein 0.0038 0.0034 0.0032
Entamoeba histolytica tyrosine kinase, putative 0.0036 0.0013 0.0006
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0068 0.0291 0.0289
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0048 0.0118 0.0106
Loa Loa (eye worm) hypothetical protein 0.0088 0.0468 0.0466
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.1171 1 1
Leishmania major casein kinase, putative 0.0065 0.027 0.0257
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0036 0.0013 0.0011
Toxoplasma gondii diacylglycerol kinase, putative 0.0038 0.0034 0.0099
Loa Loa (eye worm) hypothetical protein 0.0106 0.0625 0.0623
Trypanosoma brucei polo-like protein kinase 0.1171 1 1
Echinococcus granulosus nervana 2 0.0139 0.0919 0.0917
Giardia lamblia Kinase, AGC PKA 0.0162 0.1118 0.1107
Entamoeba histolytica serine/threonine protein kinase STE20, putative 0.0081 0.0407 0.0401
Echinococcus granulosus casein kinase I delta 0.0065 0.027 0.0267
Brugia malayi Protein kinase domain containing protein 0.0036 0.0013 0.0011
Loa Loa (eye worm) hypothetical protein 0.0039 0.0042 0.004
Entamoeba histolytica protein kinase, putative 0.005 0.0131 0.0125
Echinococcus granulosus nervana 2 0.0139 0.0919 0.0917
Entamoeba histolytica protein kinase, putative 0.0036 0.0015 0.0009
Loa Loa (eye worm) AUR protein kinase 0.0149 0.1008 0.1006
Loa Loa (eye worm) hypothetical protein 0.0042 0.0066 0.0064
Trichomonas vaginalis STE family protein kinase 0.0082 0.042 0.0408
Echinococcus granulosus neuroglian 0.0104 0.061 0.0608
Schistosoma mansoni titin 0.0044 0.0084 0.0082
Giardia lamblia Kinase, NEK 0.0139 0.0916 0.0904
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0045 0.0092 0.009
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0036 0.0013 0.0011
Brugia malayi RhoGEF domain containing protein 0.0038 0.0034 0.0032
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0259 0.1974 0.1972
Echinococcus multilocularis tyrosine protein kinase pr2 0.0036 0.0013 0.0011
Schistosoma mansoni tyrosine kinase 0.0075 0.0359 0.0357
Schistosoma mansoni tyrosine kinase 0.0071 0.0323 0.0321
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0165 0.1143 0.1132
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0979 0.831 0.8309
Entamoeba histolytica tyrosine kinase, putative 0.0036 0.0013 0.0006
Echinococcus granulosus RNA directed DNA polymerase 0.0045 0.0088 0.0086
Entamoeba histolytica protein kinase, putative 0.0036 0.0013 0.0006
Entamoeba histolytica serine/threonine kinase, putative 0.0036 0.0013 0.0006
Trichomonas vaginalis AGC family protein kinase 0.0292 0.2265 0.2256
Echinococcus granulosus serine:threonine protein kinase 0.0114 0.0698 0.0696
Giardia lamblia Kinase, CMGC GSK 0.013 0.0842 0.083
Loa Loa (eye worm) hypothetical protein 0.0156 0.1069 0.1067
Echinococcus granulosus tyrosine protein kinase Fyn 0.0162 0.1121 0.1119
Trypanosoma brucei SNF1-related protein kinases, putative 0.0048 0.0118 0.0106
Echinococcus granulosus unc 13 munc13 0.004 0.0047 0.0045
Brugia malayi Protein kinase domain containing protein 0.0036 0.0013 0.0011
Schistosoma mansoni serine/threonine protein kinase 0.0041 0.0061 0.0058
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0042 0.0066 0.0064
Schistosoma mansoni serine/threonine protein kinase 0.0241 0.182 0.1818
Echinococcus multilocularis serine threonine protein kinase 0.0193 0.1392 0.1391
Brugia malayi Sex muscle abnormal protein 5 0.006 0.0224 0.0222
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0048 0.0119 0.0117
Echinococcus granulosus Immunoglobulin 0.0085 0.0444 0.0442
Entamoeba histolytica protein kinase domain containing protein 0.0036 0.0013 0.0006
Schistosoma mansoni nck2/grb4 0.006 0.0224 0.0222
Loa Loa (eye worm) TK/FER protein kinase 0.0069 0.0305 0.0303
Loa Loa (eye worm) TK/DDR protein kinase 0.0036 0.0013 0.0011
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0048 0.0119 0.0117
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0036 0.0013 0.0011
Schistosoma mansoni serine/threonine protein kinase 0.0074 0.0351 0.0349
Brugia malayi Protein kinase domain containing protein 0.0036 0.0013 0.0011
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.1129 0.9623 0.9623
Schistosoma mansoni hypothetical protein 0.0069 0.0301 0.0299
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0077 0.0375 0.0373
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0156 0.1072 0.107
Schistosoma mansoni cell adhesion molecule 0.0039 0.0042 0.004
Entamoeba histolytica protein kinase, putative 0.0036 0.0013 0.0006
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.0211 0.1555 0.1553
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0077 0.0375 0.0373
Trichomonas vaginalis AGC family protein kinase 0.0292 0.2265 0.2256
Loa Loa (eye worm) hypothetical protein 0.0036 0.0013 0.0011
Entamoeba histolytica protein kinase, putative 0.0036 0.0013 0.0006
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0055 0.0178 0.0176
Entamoeba histolytica hypothetical protein 0.0123 0.0778 0.0773
Trichomonas vaginalis AGC family protein kinase 0.0153 0.1042 0.1031
Schistosoma mansoni cell adhesion molecule 0.0108 0.0649 0.0647
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0118 0.0106
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0139 0.0919 0.0917
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0139 0.0916 0.8168
Entamoeba histolytica tyrosine kinase, putative 0.0036 0.0013 0.0006
Echinococcus multilocularis protein kinase c eta type 0.0038 0.0034 0.0032
Loa Loa (eye worm) MH2 domain-containing protein 0.0144 0.0964 0.0962
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0149 0.1008 0.9003
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0036 0.0013 0.0011
Brugia malayi Protein kinase domain containing protein 0.0036 0.0013 0.0011
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.1171 1 1
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0036 0.0013 0.0006
Loa Loa (eye worm) hypothetical protein 0.0036 0.0013 0.0011
Echinococcus multilocularis raf serine:threonine protein kinase 0.0074 0.0351 0.0349
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0202 0.1476 0.1474
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0085 0.0444 0.0442
Loa Loa (eye worm) TK/FER protein kinase 0.0069 0.0305 0.0303
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0168 0.1173 0.1162
Entamoeba histolytica protein kinase, putative 0.0056 0.0187 0.0181
Entamoeba histolytica PH domain containing protein kinase, putative 0.0074 0.0346 0.034
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0162 0.1118 0.1107
Schistosoma mansoni tyrosine kinase 0.0162 0.1121 0.1119
Brugia malayi Protein kinase domain containing protein 0.0069 0.0305 0.0303
Echinococcus granulosus mitogen activated protein kinase 14 0.0165 0.1143 0.1141
Echinococcus granulosus receptor type guanylyl cyclase 0.0036 0.0013 0.0011
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0036 0.0013 0.0011
Brugia malayi intracellular kinase 0.013 0.0842 0.084
Schistosoma mansoni serine/threonine protein kinase 0.0068 0.0291 0.0289
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0202 0.1476 0.1474
Trichomonas vaginalis CMGC family protein kinase 0.0098 0.0559 0.0547
Brugia malayi protein unc-22 0.0044 0.0084 0.0082
Trichomonas vaginalis CK1 family protein kinase 0.0065 0.027 0.0257
Entamoeba histolytica hypothetical protein 0.0043 0.0078 0.0072
Onchocerca volvulus 0.0052 0.0151 0.0151
Schistosoma mansoni serine/threonine protein kinase 0.0128 0.082 0.0818
Loa Loa (eye worm) AGC/AKT protein kinase 0.0292 0.2265 0.2264
Brugia malayi bone morphogenetic protein type 1 receptor 0.0036 0.0013 0.0011
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0068 0.0291 0.0289
Entamoeba histolytica hypothetical protein 0.0036 0.0013 0.0006
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.008 0.0397 0.0385
Onchocerca volvulus 0.0036 0.0013 0.0013
Trypanosoma cruzi casein kinase, putative 0.0065 0.027 0.0257
Schistosoma mansoni tyrosine kinase 0.0036 0.0013 0.0011
Brugia malayi hypothetical protein 0.0043 0.0078 0.0076
Echinococcus granulosus tyrosine protein kinase HCK 0.0102 0.0593 0.0591
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0069 0.03 0.0298
Entamoeba histolytica hypothetical protein 0.0036 0.0013 0.0006
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0036 0.0013 0.0011
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0048 0.0119 0.0117
Echinococcus multilocularis Glutaredoxin protein 5 0.0139 0.0919 0.0917
Schistosoma mansoni cell adhesion molecule 0.0042 0.0066 0.0064
Echinococcus multilocularis casein kinase I alpha 0.0065 0.027 0.0267
Brugia malayi Protein kinase domain containing protein 0.0114 0.0698 0.0696
Echinococcus multilocularis integrin linked protein kinase 0.0036 0.0013 0.0011
Echinococcus multilocularis 0.0195 0.1414 0.1412
Echinococcus granulosus natriuretic peptide receptor 1 0.0036 0.0013 0.0011
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0059 0.0212 0.0199
Echinococcus multilocularis mitogen activated protein kinase 14 0.0165 0.1143 0.1141
Schistosoma mansoni serine/threonine protein kinase 0.0036 0.0013 0.0011
Loa Loa (eye worm) AGC/PKA protein kinase 0.0068 0.0291 0.0289
Echinococcus granulosus serine:threonine protein kinase PLK1 0.1171 1 1
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0211 0.1555 0.1553
Entamoeba histolytica protein kinase domain containing protein 0.0059 0.0212 0.0206
Schistosoma mansoni ste20-related kinase 0.0216 0.1598 0.1597
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0114 0.0703 0.0701
Schistosoma mansoni serine/threonine protein kinase 0.0047 0.011 0.0108
Loa Loa (eye worm) hypothetical protein 0.0114 0.0698 0.0696
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0068 0.0291 0.0289
Schistosoma mansoni protein kinase 0.0036 0.0013 0.0011
Echinococcus multilocularis tyrosine kinase 0.0036 0.0013 0.0011
Schistosoma mansoni protein kinase 0.0035 0.0006 0.0004
Onchocerca volvulus 0.0069 0.0305 0.0305
Schistosoma mansoni hypothetical protein 0.0035 0.0006 0.0004
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0118 0.0106
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0047 0.011 0.0097
Brugia malayi Temporarily assigned gene name protein 59 0.0145 0.0972 0.097
Echinococcus multilocularis rho associated protein kinase 0.0351 0.2785 0.2784
Brugia malayi HSF-type DNA-binding domain containing protein 0.012 0.0749 0.0747
Schistosoma mansoni serine/threonine protein kinase 0.0065 0.027 0.0268
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0072 0.0327 0.0324
Leishmania major protein kinase A catalytic subunit isoform 1 0.0068 0.0291 0.0279
Leishmania major protein kinase A catalytic subunit 0.0068 0.0291 0.0279
Entamoeba histolytica leucine-rich repeat domain-containing protein 0.0036 0.0015 0.0009
Entamoeba histolytica hypothetical protein 0.0043 0.0078 0.0072
Giardia lamblia Kinase, STE STE20 0.0081 0.0407 0.0394
Echinococcus granulosus mitogen activated protein kinase 11 0.0165 0.1143 0.1141
Echinococcus granulosus defective proboscis extension response 0.0085 0.0444 0.0442
Echinococcus multilocularis N chimaerin 0.0072 0.0327 0.0324
Entamoeba histolytica protein kinase, putative 0.0064 0.026 0.0254
Schistosoma mansoni protein kinase 0.0036 0.0013 0.0011
Loa Loa (eye worm) hypothetical protein 0.0134 0.0873 0.0871
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0036 0.0013 0.0011
Echinococcus granulosus Diacylglycerol kinase theta 0.0038 0.0034 0.0032
Echinococcus granulosus epidermal growth factor receptor 0.0437 0.3543 0.3541
Entamoeba histolytica tyrosine- protein kinase 2, putative 0.0036 0.0013 0.0006
Echinococcus granulosus tyrosine protein kinase csk 0.0036 0.0013 0.0011
Plasmodium falciparum calcium-dependent protein kinase 4 0.0048 0.0119 0.0961
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0077 0.0375 0.0373
Echinococcus multilocularis peroxidasin 0.004 0.0045 0.0042
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0123 0.0778 0.0767
Loa Loa (eye worm) TK/FER protein kinase 0.0069 0.0305 0.0303
Schistosoma mansoni protein kinase 0.0048 0.0119 0.0117
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0072 0.0327 0.0324
Loa Loa (eye worm) TK/FER protein kinase 0.0036 0.0013 0.0011
Entamoeba histolytica protein kinase, putative 0.0036 0.0013 0.0006
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0048 0.0118 0.0106
Schistosoma mansoni src-type protein tyrosine kinase-related 0.0036 0.0013 0.0011
Entamoeba histolytica protein kinase, putative 0.0286 0.2211 0.2206
Echinococcus granulosus protein kinase C gamma type 0.0193 0.1392 0.1391
Loa Loa (eye worm) hypothetical protein 0.0038 0.0034 0.0032
Trichomonas vaginalis STE family protein kinase 0.0082 0.042 0.0408
Loa Loa (eye worm) P21-Rho-binding domain-containing protein 0.0035 0.0006 0.0004
Echinococcus granulosus epidermal growth factor receptor 0.0671 0.5602 0.5601
Giardia lamblia Kinase, CAMK CAMKL 0.0048 0.0118 0.0106
Loa Loa (eye worm) cytochrome P450 family protein 0.0063 0.0252 0.025
Brugia malayi Protein kinase domain containing protein 0.0489 0.3994 0.3993
Echinococcus multilocularis serine:threonine protein kinase 3 0.0274 0.211 0.2108
Loa Loa (eye worm) raf kinase 0.0038 0.0034 0.0032
Echinococcus multilocularis transfer RNA-Thr 0.0036 0.0013 0.0011
Trypanosoma brucei aurora B kinase 0.0149 0.1008 0.0997
Echinococcus multilocularis aurora kinase A 0.0149 0.1008 0.1006
Echinococcus multilocularis neuroglian 0.0104 0.061 0.0608
Loa Loa (eye worm) hypothetical protein 0.0038 0.0034 0.0032
Trichomonas vaginalis CAMK family protein kinase 0.0563 0.4647 0.464
Echinococcus granulosus tyrosine protein kinase Fyn 0.0162 0.1121 0.1119
Entamoeba histolytica hypothetical protein 0.0036 0.0015 0.0009
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0048 0.0119 0.0117
Loa Loa (eye worm) TK protein kinase 0.0036 0.0013 0.0011
Entamoeba histolytica protein kinase, putative 0.0036 0.0013 0.0006
Entamoeba histolytica diacylglycerol kinase, putative 0.0038 0.0034 0.0028
Loa Loa (eye worm) hypothetical protein 0.01 0.0579 0.0577
Brugia malayi Protein kinase domain containing protein 0.0036 0.0013 0.0011
Plasmodium falciparum protein kinase, putative 0.0059 0.0212 0.1802
Trichomonas vaginalis CAMK family protein kinase 0.1171 1 1
Entamoeba histolytica protein kinase with ankyrin repeats, putative 0.0036 0.0013 0.0006
Loa Loa (eye worm) RGC/RGC protein kinase 0.0036 0.0013 0.0011
Brugia malayi P38 map kinase family protein 2 0.0165 0.1143 0.1141
Schistosoma mansoni tyrosine kinase 0.0269 0.2064 0.2063
Trichomonas vaginalis STE family protein kinase 0.0082 0.042 0.0408
Entamoeba histolytica tyrosine kinase, putative 0.0036 0.0013 0.0006
Brugia malayi Protein kinase domain containing protein 0.0036 0.0013 0.0011
Onchocerca volvulus 0.0329 0.2586 0.2586
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0118 0.0106
Echinococcus multilocularis nervana 2 0.0139 0.0919 0.0917
Schistosoma mansoni hypothetical protein 0.0348 0.2756 0.2755
Brugia malayi Protein kinase domain containing protein 0.0069 0.0305 0.0303
Onchocerca volvulus 0.0351 0.2785 0.2785
Schistosoma mansoni serine/threonine protein kinase 0.0048 0.0118 0.0116
Schistosoma mansoni protein kinase 0.0082 0.042 0.0418
Echinococcus granulosus activated cdc42 kinase 1 0.0036 0.0013 0.0011
Echinococcus granulosus calcium:calmodulin dependent protein kinase I 0.0065 0.027 0.0268
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0048 0.0119 0.0106
Echinococcus multilocularis calcium:calmodulin dependent protein kinase I 0.0065 0.027 0.0268
Loa Loa (eye worm) hypothetical protein 0.0038 0.0034 0.0032
Schistosoma mansoni serine/threonine kinase 0.0091 0.05 0.0498
Schistosoma mansoni transcription factor LCR-F1 0.0043 0.0078 0.0076
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0135 0.0885 0.0883
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0688 0.5747 0.5746
Brugia malayi Protein kinase domain containing protein 0.0195 0.141 0.1409
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0165 0.1143 0.1132
Entamoeba histolytica protein kinase domain containing protein 0.0036 0.0013 0.0006
Loa Loa (eye worm) hypothetical protein 0.006 0.0224 0.0222
Schistosoma mansoni serine/threonine protein kinase 0.008 0.0397 0.0395
Echinococcus multilocularis c src tyrosine kinase 0.0096 0.0541 0.0539
Trypanosoma brucei casein kinase I, isoform 2 0.0065 0.027 0.0257
Schistosoma mansoni hypothetical protein 0.0035 0.0006 0.0004
Echinococcus multilocularis kinase suppressor of Ras 1 0.0036 0.0013 0.0011
Schistosoma mansoni serine/threonine protein kinase 0.0183 0.1303 0.1301
Echinococcus multilocularis growth factor receptor bound protein 2 0.006 0.0224 0.0222
Loa Loa (eye worm) TK/FER protein kinase 0.0036 0.0013 0.0011
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.006 0.0224 0.0222
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0068 0.0291 0.0279
Entamoeba histolytica protein kinase, putative 0.0149 0.1008 0.1003
Echinococcus granulosus N chimaerin 0.0072 0.0327 0.0324
Entamoeba histolytica protein kinase domain containing protein 0.0036 0.0013 0.0006
Giardia lamblia Kinase, NEK 0.0139 0.0916 0.0904
Onchocerca volvulus 0.0069 0.0305 0.0305
Schistosoma mansoni serine/threonine protein kinase 0.0123 0.0778 0.0776
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0286 0.2211 0.2209
Echinococcus granulosus cyclin dependent kinase 5 0.0119 0.0744 0.0742
Trypanosoma cruzi cdc2-related kinase 3 0.0119 0.0744 0.0733
Echinococcus multilocularis casein kinase i 0.0065 0.027 0.0267
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0099 0.0568 0.0566
Brugia malayi Peroxidasin 0.004 0.0045 0.0042
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0165 0.1143 0.1141
Brugia malayi Kinase associated domain 1 family protein 0.0069 0.0301 0.0299
Echinococcus granulosus hemicentin 1 0.0039 0.0042 0.004
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0118 0.0106
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0139 0.0919 0.0917
Echinococcus multilocularis rac serine:threonine kinase 0.0168 0.1173 0.1171
Onchocerca volvulus Basement membrane proteoglycan homolog 0.0039 0.0042 0.0042
Echinococcus granulosus calcium activated potassium channel 0.0091 0.05 0.0498
Onchocerca volvulus 0.0136 0.0896 0.0896
Schistosoma mansoni protein kinase 0.0048 0.0119 0.0117
Trypanosoma brucei protein kinase, putative 0.013 0.0842 0.083
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0068 0.0291 0.0279
Echinococcus multilocularis natriuretic peptide receptor 1 0.0036 0.0013 0.0011
Schistosoma mansoni hypothetical protein 0.0205 0.1496 0.1494
Trichomonas vaginalis AGC family protein kinase 0.0292 0.2265 0.2256
Echinococcus multilocularis macrophage colony stimulating factor 1 receptor 0.0036 0.0013 0.0011
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0241 0.182 0.1818
Brugia malayi ephrin receptor 1 precursor 0.007 0.0311 0.0309
Schistosoma mansoni serine/threonine protein kinase 0.0149 0.1008 0.1006
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0241 0.182 0.1818
Loa Loa (eye worm) hypothetical protein 0.0036 0.0013 0.0011
Brugia malayi Tyrosine-protein kinase F09A5.2 in chromosome X, putative 0.0036 0.0013 0.0011
Schistosoma mansoni tyrosine kinase 0.0489 0.3994 0.3993
Brugia malayi Protein kinase domain containing protein 0.0147 0.0988 0.0986
Echinococcus multilocularis neurotracting:lsamp:neurotrimin:obcam 0.0039 0.0042 0.004
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.013 0.0842 0.084
Echinococcus multilocularis tyrosine protein kinase Abl 0.0185 0.1325 0.1324
Schistosoma mansoni serine/threonine protein kinase 0.0231 0.1731 0.1729
Brugia malayi Protein kinase domain containing protein 0.0036 0.0013 0.0011
Loa Loa (eye worm) TK/ALK protein kinase 0.0302 0.2352 0.2351
Trypanosoma cruzi casein kinase, putative 0.0065 0.027 0.0257
Echinococcus multilocularis tyrosine protein kinase otk 0.0039 0.0042 0.004
Brugia malayi proto-oncogene tyrosine-protein kinase FER 0.0036 0.0013 0.0011
Loa Loa (eye worm) TK/FER protein kinase 0.0069 0.0305 0.0303
Schistosoma mansoni serine/threonine protein kinase 0.0147 0.0988 0.0986
Schistosoma mansoni serine/threonine RGC 0.0036 0.0013 0.0011
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0041 0.0055 0.0053
Loa Loa (eye worm) TK protein kinase 0.0036 0.0013 0.0011
Schistosoma mansoni protein kinase 0.0036 0.0013 0.0011
Giardia lamblia Kinase, AGC AKT 0.0117 0.0727 0.0715
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0118 0.0106
Echinococcus multilocularis activin receptor type 0.0059 0.0212 0.021
Echinococcus granulosus tyrosine protein kinase pr2 0.0036 0.0013 0.0011
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0055 0.0178 0.0176
Schistosoma mansoni serine/threonine kinase 0.0147 0.0988 0.0986
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0048 0.0119 0.0117
Onchocerca volvulus 0.0072 0.0329 0.0329
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0096 0.0541 0.0539
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0068 0.0291 0.0289
Leishmania major protein kinase, putative 0.0048 0.0119 0.0106
Entamoeba histolytica tyrosine kinase, putative 0.0036 0.0013 0.0006
Schistosoma mansoni tyrosine kinase 0.0401 0.3226 0.3225
Schistosoma mansoni tyrosine kinase 0.0036 0.0013 0.0011
Schistosoma mansoni serine/threonine protein kinase 0.0147 0.0988 0.0986
Entamoeba histolytica tyrosin kinase, putative 0.0036 0.0013 0.0006
Loa Loa (eye worm) hypothetical protein 0.0083 0.0427 0.0425
Echinococcus multilocularis RNA directed DNA polymerase 0.0045 0.0088 0.0086
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0183 0.1303 0.1301
Schistosoma mansoni protein kinase 0.0082 0.042 0.0418
Entamoeba histolytica tyrosine kinase, putative 0.0036 0.0013 0.0006
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0036 0.0013 0.0011
Brugia malayi putative serine/threonine kinase SADA gamma 0.0048 0.0118 0.0116
Loa Loa (eye worm) hypothetical protein 0.0048 0.0119 0.0117
Echinococcus multilocularis tyrosine protein kinase csk 0.0036 0.0013 0.0011
Loa Loa (eye worm) hypothetical protein 0.0069 0.0305 0.0303
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0081 0.0407 0.0394
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0241 0.182 0.1818
Brugia malayi map kinase activated protein kinase protein 2 0.0429 0.3469 0.3467
Schistosoma mansoni serine/threonine protein kinase 0.0351 0.2785 0.2784
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0059 0.0212 0.0906
Brugia malayi RhoGAP domain containing protein 0.0072 0.0327 0.0324
Brugia malayi Variant SH3 domain containing protein 0.0072 0.0327 0.0324
Loa Loa (eye worm) hypothetical protein 0.0085 0.0444 0.0442
Trypanosoma cruzi p21-activated kinase 3, putative 0.0047 0.011 0.0097
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0234 0.175 0.1748
Echinococcus granulosus casein kinase I delta 0.0065 0.027 0.0267
Echinococcus granulosus cyclin dependent kinase 1 0.0119 0.0744 0.0742
Schistosoma mansoni serine/threonine protein kinase 0.0128 0.082 0.0818
Loa Loa (eye worm) TK/FER protein kinase 0.0036 0.0013 0.0011
Entamoeba histolytica serine/threonine-protein kinase 3, putative 0.0081 0.0407 0.0401
Echinococcus granulosus integrin linked protein kinase 0.0036 0.0013 0.0011
Echinococcus granulosus serine:threonine protein kinase 0.0114 0.0698 0.0696
Brugia malayi Protein kinase domain containing protein 0.0147 0.0988 0.0986
Onchocerca volvulus 0.0036 0.0013 0.0013
Brugia malayi Protein kinase domain containing protein 0.0036 0.0013 0.0011
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0128 0.082 0.0818
Echinococcus granulosus myotubularin protein 13 0.0045 0.0089 0.0087
Trichomonas vaginalis STE family protein kinase 0.0082 0.042 0.0408
Schistosoma mansoni serine/threonine protein kinase 0.0068 0.0291 0.0289
Entamoeba histolytica receptor protein kinase, putative 0.0036 0.0013 0.0006
Entamoeba histolytica protein kinase, putative 0.0036 0.0013 0.0006
Echinococcus granulosus serine:threonine protein kinase N2 0.0147 0.0988 0.0986
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0036 0.0013 0.0011
Brugia malayi Pleckstrin Homology Domain 0.0045 0.0089 0.0087
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0148 0.1002 0.1
Entamoeba histolytica protein kinase, putative 0.0065 0.027 0.0264
Brugia malayi Immunoglobulin I-set domain containing protein 0.0039 0.0042 0.004
Trichomonas vaginalis AGC family protein kinase 0.0292 0.2265 0.2256
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0077 0.0375 0.0373
Entamoeba histolytica casein kinase, putative 0.0065 0.027 0.0264
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0068 0.0291 0.0279
Entamoeba histolytica protein kinase domain containing protein 0.004 0.0044 0.0038
Brugia malayi Ras association domain family 1 isoform A 0.0038 0.0034 0.0032
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0048 0.0119 0.0117
Loa Loa (eye worm) hypothetical protein 0.0085 0.0446 0.0444
Trichomonas vaginalis CAMK family protein kinase 0.1171 1 1
Echinococcus granulosus titin 0.0044 0.0084 0.0082
Trichomonas vaginalis AGC family protein kinase 0.0149 0.1008 0.0997
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.0036 0.0013 0.0011
Entamoeba histolytica casein kinase, putative 0.0098 0.0559 0.0554
Echinococcus multilocularis nervana 2 0.0139 0.0919 0.0917
Trypanosoma brucei cdc2-related kinase 3 0.0119 0.0744 0.0733
Brugia malayi Immunoglobulin I-set domain containing protein 0.0039 0.0042 0.004
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0082 0.042 0.0418
Entamoeba histolytica protein kinase domain containing protein 0.0036 0.0013 0.0006
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0123 0.0778 0.0767
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0161 0.1114 0.1112
Onchocerca volvulus 0.013 0.0842 0.0842
Schistosoma mansoni growth factor receptor-bound protein 0.006 0.0224 0.0222
Entamoeba histolytica cell division protein kinase 2, putative 0.0119 0.0744 0.0739
Brugia malayi diacylglycerol kinase 0.0038 0.0034 0.0032
Entamoeba histolytica p21-activated kinase 0.0088 0.0474 0.0468
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0039 0.0042 0.004
Echinococcus granulosus tyrosine kinase 0.0135 0.0885 0.0883
Brugia malayi Protein kinase domain containing protein 0.0036 0.0013 0.0011
Loa Loa (eye worm) hypothetical protein 0.0038 0.0034 0.0032
Schistosoma mansoni tyrosine kinase 0.0036 0.0013 0.0011
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0068 0.0291 0.0279
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0082 0.042 0.0418
Echinococcus granulosus c-Jun N-terminal kinases 0.0283 0.2183 0.2182
Echinococcus multilocularis protein kinase shaggy 0.013 0.0842 0.084
Schistosoma mansoni tyrosine kinase 0.0096 0.0541 0.0539
Schistosoma mansoni tyrosine kinase 0.0036 0.0013 0.0011
Brugia malayi Protein kinase domain containing protein 0.0211 0.1555 0.1553
Brugia malayi Protein kinase domain containing protein 0.0036 0.0013 0.0011
Entamoeba histolytica protein kinase, putative 0.0065 0.027 0.0264
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0437 0.3543 0.3541
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0036 0.0013 0.0006
Loa Loa (eye worm) hypothetical protein 0.0045 0.0088 0.0086
Echinococcus granulosus 3'partial|serine:threonine protein kinase PAK 2 0.0035 0.0006 0.0004
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.013 0.0842 0.083
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0118 0.0106
Trichomonas vaginalis AGC family protein kinase 0.0077 0.0375 0.0363
Echinococcus multilocularis insulin receptor 0.0489 0.3994 0.3993
Echinococcus granulosus protein kinase c eta type 0.0038 0.0034 0.0032
Brugia malayi ribosomal protein S6 kinase alpha 3 0.0117 0.0727 0.0725
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0065 0.027 0.0267
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.0091 0.05 0.0498
Echinococcus granulosus protein kinase shaggy 0.013 0.0842 0.084
Onchocerca volvulus 0.0365 0.2906 0.2906
Echinococcus granulosus C2 calcium dependent membrane targeting 0.004 0.0047 0.0045
Schistosoma mansoni nephrin 0.0042 0.0066 0.0064
Toxoplasma gondii casein kinase I 0.0065 0.027 0.1168
Schistosoma mansoni tyrosine kinase 0.0036 0.0013 0.0011
Trichomonas vaginalis AGC family protein kinase 0.0149 0.1008 0.0997
Schistosoma mansoni tyrosine kinase 0.0437 0.3543 0.3541
Giardia lamblia Kinase, CMGC MAPK 0.008 0.0397 0.0385
Entamoeba histolytica hypothetical protein 0.0036 0.0013 0.0006
Loa Loa (eye worm) TK/FAK protein kinase 0.0036 0.0013 0.0011
Giardia lamblia Kinase, CMGC CK2 0.0098 0.0559 0.0547
Schistosoma mansoni serine/threonine protein kinase 0.0183 0.1303 0.1301
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0119 0.0744 0.0742
Trichomonas vaginalis STE family protein kinase 0.0139 0.0916 0.0904
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0048 0.0118 0.0106
Entamoeba histolytica serine/threonine kinase, putative 0.0036 0.0013 0.0006
Echinococcus multilocularis tyrosine protein kinase HCK 0.0102 0.0593 0.0591
Loa Loa (eye worm) hypothetical protein 0.0039 0.0042 0.004
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0162 0.1121 0.1119
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0135 0.0885 0.0883
Onchocerca volvulus 0.0069 0.0305 0.0305
Brugia malayi hypothetical protein 0.0088 0.0468 0.0466
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0156 0.1072 0.107
Plasmodium vivax calcium-dependent protein kinase, putative 0.0048 0.0119 0.0961
Schistosoma mansoni tyrosine kinase 0.0036 0.0013 0.0011
Entamoeba histolytica tyrosine kinase, putative 0.0036 0.0013 0.0006
Schistosoma mansoni serine/threonine protein kinase 0.0119 0.0744 0.0742
Brugia malayi MH2 domain containing protein 0.0144 0.0964 0.0962
Echinococcus granulosus neuroglian 0.0042 0.0066 0.0064
Echinococcus granulosus serine threonine protein kinase nrc 0.0162 0.1118 0.1117
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.1045 0.8887 0.8887
Echinococcus multilocularis Rac GTPase activating protein 1 0.0038 0.0034 0.0032
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0491 0.4018 0.4016
Loa Loa (eye worm) hypothetical protein 0.0303 0.2361 0.2359
Entamoeba histolytica protein kinase, putative 0.0036 0.0013 0.0006
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0259 0.1974 0.1972
Echinococcus multilocularis tyrosine protein kinase Blk 0.0135 0.0885 0.0883
Trypanosoma cruzi casein kinase, putative 0.0065 0.027 0.0257
Brugia malayi Protein kinase domain containing protein 0.0036 0.0013 0.0011
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0082 0.042 0.0418
Plasmodium falciparum calcium-dependent protein kinase 5 0.0048 0.0119 0.0961
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.1171 1 1
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0202 0.1476 0.1474
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.0211 0.1555 0.1553
Trichomonas vaginalis CMGC family protein kinase 0.0119 0.0744 0.0733
Schistosoma mansoni serine/threonine protein kinase 0.0091 0.05 0.0498
Loa Loa (eye worm) TK/Met protein kinase 0.0036 0.0013 0.0011
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0147 0.0988 0.0986
Echinococcus multilocularis serine:threonine protein kinase 38 0.0147 0.0988 0.0986
Brugia malayi serine/threonine-protein kinase PAK 7 0.0247 0.1865 0.1863
Brugia malayi Immunoglobulin I-set domain containing protein 0.0278 0.2139 0.2138
Echinococcus multilocularis X box binding protein 1 0.0348 0.2756 0.2755
Echinococcus multilocularis Immunoglobulin 0.0085 0.0444 0.0442
Echinococcus granulosus tyrosine protein kinase shark 0.0069 0.0305 0.0303
Entamoeba histolytica tyrosine kinase, putative 0.0036 0.0013 0.0006
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0098 0.0559 0.0557
Echinococcus granulosus NDR protein kinase 0.0147 0.0988 0.0986
Entamoeba histolytica protein kinase, putative 0.0048 0.0119 0.0113
Schistosoma mansoni serine/threonine protein kinase 0.0048 0.0118 0.0116
Plasmodium falciparum protein kinase 5 0.0119 0.0744 0.6616
Schistosoma mansoni hypothetical protein 0.0043 0.0078 0.0076
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0147 0.0988 0.0986
Loa Loa (eye worm) TK/CSK protein kinase 0.0036 0.0013 0.0011
Brugia malayi P21-Rho-binding domain containing protein 0.0035 0.0006 0.0004
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0043 0.0078 0.0076
Entamoeba histolytica tyrosine kinase, putative 0.0036 0.0013 0.0006
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0118 0.0106
Echinococcus granulosus tyrosine protein kinase otk 0.0039 0.0042 0.004
Brugia malayi Protein kinase domain containing protein 0.0036 0.0013 0.0011
Schistosoma mansoni protein kinase C mu 0.0153 0.1041 0.1039
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.0048 0.0118 0.0106
Loa Loa (eye worm) hypothetical protein 0.0088 0.0468 0.0466
Trichomonas vaginalis AGC family protein kinase 0.0068 0.0291 0.0279
Echinococcus granulosus X box binding protein 1 0.0348 0.2756 0.2755
Loa Loa (eye worm) hypothetical protein 0.0092 0.0503 0.0501
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0149 0.1008 0.1003
Echinococcus granulosus titin 0.0044 0.0084 0.0082
Brugia malayi Tyrosine-protein kinase abl-1 0.0185 0.1325 0.1324
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0042 0.0066 0.0064
Echinococcus multilocularis hemicentin 1 0.0039 0.0042 0.004
Echinococcus multilocularis neuropeptide receptor A26 0.0558 0.4608 0.4607
Entamoeba histolytica heat shock transcription factor, putative 0.012 0.0749 0.0743
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0048 0.0119 0.0961
Brugia malayi Stress-activated protein kinase jnk-1 0.0283 0.2183 0.2182
Brugia malayi C1-like domain containing protein 0.0153 0.1041 0.1039
Entamoeba histolytica protein kinase domain containing protein 0.0036 0.0013 0.0006
Echinococcus multilocularis heat shock protein 70 0.0036 0.0013 0.0011
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0231 0.1731 0.1729
Entamoeba histolytica protein kinase domain containing protein 0.0036 0.0013 0.0006
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0156 0.1072 0.107
Echinococcus multilocularis mitogen activated protein kinase 0.008 0.0397 0.0395
Onchocerca volvulus 0.0036 0.0013 0.0013
Trichomonas vaginalis CAMK family protein kinase 0.1171 1 1
Brugia malayi serine/threonine-protein kinase 6 0.0149 0.1008 0.1006
Giardia lamblia Kinase, CK1 Casein kinase 0.0065 0.027 0.0257
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0042 0.0066 0.0064
Entamoeba histolytica tyrosin kinase, putative 0.0036 0.0013 0.0006
Echinococcus multilocularis neuroglian 0.0042 0.0066 0.0064
Echinococcus granulosus tyrosine protein kinase Fes:Fps 0.0036 0.0013 0.0011
Echinococcus multilocularis protein kinase 0.0036 0.0013 0.0011
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0165 0.1143 0.1132
Brugia malayi Immunoglobulin I-set domain containing protein 0.0039 0.0042 0.004
Entamoeba histolytica protein kinase domain containing protein 0.0098 0.0559 0.0554
Loa Loa (eye worm) hypothetical protein 0.0036 0.0013 0.0011
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0118 0.0106
Trypanosoma cruzi casein kinase, putative 0.0065 0.027 0.0257
Toxoplasma gondii AGC kinase 0.0286 0.2211 1
Trypanosoma cruzi cdc2-related kinase 1 0.0119 0.0744 0.0733
Schistosoma mansoni protein kinase 0.0098 0.0559 0.0557
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0043 0.007 0.0058
Schistosoma mansoni tyrosine kinase 0.0162 0.1121 0.1119
Brugia malayi Fibronectin type III domain containing protein 0.0088 0.0468 0.0466
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0042 0.0066 0.0064
Echinococcus multilocularis twitchin 0.0041 0.0061 0.0058
Schistosoma mansoni protein kinase 0.0036 0.0013 0.0011
Loa Loa (eye worm) CMGC/GSK protein kinase 0.013 0.0842 0.084
Brugia malayi Immunoglobulin I-set domain containing protein 0.0039 0.0042 0.004
Loa Loa (eye worm) hypothetical protein 0.0156 0.1069 0.1067
Echinococcus granulosus activin receptor type 0.0059 0.0212 0.021
Loa Loa (eye worm) TK/ROR protein kinase 0.0055 0.0178 0.0176
Entamoeba histolytica protein kinase, putative 0.0036 0.0013 0.0006
Loa Loa (eye worm) AGC/PKA protein kinase 0.0068 0.0291 0.0289
Entamoeba histolytica protein kinase, putative 0.0123 0.0778 0.0773
Trichomonas vaginalis CAMK family protein kinase 0.1171 1 1
Plasmodium vivax casein kinase 1, putative 0.0065 0.027 0.2323
Brugia malayi WH1 domain containing protein 0.0035 0.0006 0.0004
Loa Loa (eye worm) TK/FER protein kinase 0.0036 0.0013 0.0011
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0068 0.0291 0.0289
Echinococcus granulosus fibroblast growth factor receptor 4 0.0259 0.1974 0.1972
Leishmania major protein kinase, putative 0.0149 0.1008 0.0997
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.0274 0.211 0.2108
Loa Loa (eye worm) hypothetical protein 0.0036 0.0013 0.0011
Loa Loa (eye worm) hypothetical protein 0.01 0.0579 0.0577
Echinococcus multilocularis protein KINase family member (kin 25) 0.0036 0.0013 0.0011
Leishmania major protein kinase, putative 0.0081 0.0407 0.0394
Trichomonas vaginalis CMGC family protein kinase 0.013 0.0842 0.083
Entamoeba histolytica protein kinase, putative 0.0036 0.0013 0.0006
Trypanosoma brucei STE20-like serine/threonine-protein kinase 1, putative 0.0081 0.0407 0.0394
Echinococcus multilocularis epidermal growth factor receptor 0.0671 0.5602 0.5601
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0043 0.0078 0.0076
Echinococcus granulosus lachesin 0.0039 0.0042 0.004
Onchocerca volvulus 0.0092 0.0503 0.0503
Echinococcus granulosus tyrosine protein kinase Srms 0.0069 0.0305 0.0303
Schistosoma mansoni hypothetical protein 0.0069 0.0301 0.0299
Echinococcus granulosus tyrosine protein kinase csk 0.0036 0.0013 0.0011
Echinococcus granulosus raf serine:threonine protein kinase 0.0074 0.0351 0.0349
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0048 0.0118 0.0957
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0187 0.1339 0.1337
Schistosoma mansoni serine/threonine protein kinase 0.0091 0.05 0.0498
Loa Loa (eye worm) TK/FER protein kinase 0.0069 0.0305 0.0303
Entamoeba histolytica serine/threonine protein kinase, putative 0.0048 0.0118 0.0112
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0036 0.0016 0.0014
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0118 0.0106
Leishmania major protein kinase A catalytic subunit isoform 2 0.0068 0.0291 0.0279
Echinococcus multilocularis protein tyrosine kinase 0.0036 0.0013 0.0011
Entamoeba histolytica serine/threonine kinase, putative 0.0036 0.0013 0.0006
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0068 0.0291 0.2518
Loa Loa (eye worm) hypothetical protein 0.0045 0.0089 0.0087
Schistosoma mansoni septate junction protein 0.0039 0.0042 0.004
Giardia lamblia Kinase, NEK 0.0139 0.0916 0.0904
Schistosoma mansoni tyrosine kinase 0.0489 0.3994 0.3993
Schistosoma mansoni growth factor receptor-bound protein 0.006 0.0224 0.0222
Loa Loa (eye worm) TK/INSR protein kinase 0.0489 0.3994 0.3993
Schistosoma mansoni serine/threonine protein kinase 0.0048 0.0118 0.0116
Brugia malayi Protein kinase domain containing protein 0.0036 0.0013 0.0011
Schistosoma mansoni tyrosine kinase 0.0401 0.3226 0.3225
Echinococcus granulosus retinal guanylyl cyclase 2 0.0036 0.0013 0.0011
Trichomonas vaginalis AGC family protein kinase 0.0292 0.2265 0.2256
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0072 0.0327 0.0324
Loa Loa (eye worm) TK protein kinase 0.0278 0.2139 0.2138
Loa Loa (eye worm) TK/EGFR protein kinase 0.0671 0.5602 0.5601
Loa Loa (eye worm) TKL/RAF/KSR protein kinase 0.0036 0.0013 0.0011
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0056 0.0187 0.0181
Trypanosoma brucei cdc2-related kinase 1 0.0119 0.0744 0.0733
Trypanosoma brucei Casein kinase II 0.0098 0.0559 0.0547
Schistosoma mansoni ephrin receptor 0.0108 0.0646 0.0644
Loa Loa (eye worm) RGC/RGC protein kinase 0.0036 0.0013 0.0011
Entamoeba histolytica protein kinase domain containing protein 0.0036 0.0013 0.0006
Trypanosoma brucei protein kinase, putative 0.008 0.0397 0.0385
Echinococcus multilocularis neural Wiskott Aldrich syndrome protein 0.0035 0.0006 0.0004
Schistosoma mansoni tyrosine kinase 0.0036 0.0013 0.0011
Echinococcus granulosus protein kinase 0.0036 0.0013 0.0011
Echinococcus multilocularis ephrin type A receptor 4 A 0.0108 0.0646 0.0644
Schistosoma mansoni serine/threonine-protein kinase 0.0168 0.1173 0.1171
Brugia malayi Receptor family ligand binding region containing protein 0.0036 0.0013 0.0011
Brugia malayi Tyrosine-protein kinase PR2 0.0036 0.0013 0.0011
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0118 0.0106
Plasmodium falciparum serine/threonine protein kinase, putative 0.0149 0.1008 0.9003
Echinococcus multilocularis geminin 0.0205 0.1496 0.1494
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0082 0.042 0.0418
Brugia malayi casein kinase I 0.0065 0.027 0.0267
Loa Loa (eye worm) TK/FER protein kinase 0.0069 0.0305 0.0303
Loa Loa (eye worm) hypothetical protein 0.0039 0.0042 0.004
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.0047 0.011 0.0108
Schistosoma mansoni serine/threonine protein kinase 0.0068 0.0291 0.0289
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0123 0.0782 0.077
Schistosoma mansoni septate junction protein 0.0039 0.0042 0.004
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0048 0.0119 0.0117
Entamoeba histolytica ankyrin repeat protein 0.0036 0.0013 0.0006
Trichomonas vaginalis CMGC family protein kinase 0.0119 0.0744 0.0733
Loa Loa (eye worm) TK/FER protein kinase 0.0069 0.0305 0.0303
Echinococcus multilocularis cyclin dependent kinase 1 0.0119 0.0744 0.0742
Brugia malayi Protein kinase domain containing protein 0.0036 0.0013 0.0011
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0036 0.0013 0.0006
Entamoeba histolytica serine/threonine protein kinase, putative 0.1171 1 1
Brugia malayi Variant SH3 domain containing protein 0.0041 0.0055 0.0053
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0065 0.0265 0.0263
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0234 0.175 0.1748
Plasmodium falciparum casein kinase 2, alpha subunit 0.0098 0.0559 0.4944
Echinococcus multilocularis PAK box P21 Rho binding 0.0058 0.0205 0.0203
Brugia malayi Protein kinase domain containing protein 0.0091 0.05 0.0498
Plasmodium vivax glycogen synthase kinase 3, putative 0.013 0.0842 0.7499
Loa Loa (eye worm) TK/FER protein kinase 0.0069 0.0305 0.0303
Echinococcus granulosus Glutaredoxin protein 5 0.0139 0.0919 0.0917
Trichomonas vaginalis CMGC family protein kinase 0.008 0.0397 0.0385
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0162 0.1118 0.1117
Loa Loa (eye worm) TK/FER protein kinase 0.0069 0.0305 0.0303
Trypanosoma cruzi casein kinase II, putative 0.0098 0.0559 0.0547
Entamoeba histolytica hypothetical protein 0.0036 0.0013 0.0006
Schistosoma mansoni protein tyrosine kinase 0.0036 0.0013 0.0011
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0039 0.0042 0.004
Toxoplasma gondii AGC kinase 0.0068 0.0291 0.1267
Echinococcus multilocularis lachesin 0.0039 0.0042 0.004
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.008 0.0397 0.0385
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0042 0.0066 0.0064
Schistosoma mansoni protein kinase 0.0036 0.0013 0.0011
Brugia malayi Protein kinase domain containing protein 0.0069 0.0305 0.0303
Echinococcus multilocularis myotubularin protein 13 0.0045 0.0089 0.0087
Trichomonas vaginalis AGC family protein kinase 0.0149 0.1008 0.0997
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0048 0.0119 0.0484
Schistosoma mansoni serine/threonine protein kinase 0.0187 0.1339 0.1337
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.0047 0.011 0.0108
Schistosoma mansoni tyrosine kinase 0.0069 0.0305 0.0303
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.008 0.0397 0.0385
Echinococcus multilocularis serine:threonine protein kinase 0.0114 0.0698 0.0696
Loa Loa (eye worm) hypothetical protein 0.0124 0.0791 0.0789
Brugia malayi Protein kinase domain containing protein 0.0036 0.0013 0.0011
Echinococcus granulosus casein kinase i 0.0065 0.027 0.0267
Echinococcus multilocularis neuropeptide s receptor 0.0558 0.4608 0.4607
Loa Loa (eye worm) TK protein kinase 0.0036 0.0013 0.0011
Brugia malayi serine/threonine protein kinase 6 0.0149 0.1008 0.1006
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0246 0.186 0.1859
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0068 0.0291 0.1267
Entamoeba histolytica protein kinase, putative 0.0123 0.0778 0.0773
Trypanosoma cruzi casein kinase, putative 0.0065 0.027 0.0257
Entamoeba histolytica protein kinase domain containing protein 0.013 0.0842 0.0836
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0045 0.0092 0.009
Brugia malayi Protein kinase domain containing protein 0.0036 0.0013 0.0011
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0162 0.1121 0.1119
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0036 0.0013 0.0011
Echinococcus multilocularis mitogen activated protein kinase 3 0.008 0.0397 0.0395
Echinococcus granulosus tyrosine kinase 0.0036 0.0013 0.0011
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0165 0.1143 0.1132

Activities

Activity type Activity value Assay description Source Reference
AC50 (functional) PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp2d6 Compounds with AC50 equal or less than 10 uM are considered active ChEMBL. No reference
AC50 (functional) = 2.238721139 uM PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp2c19 Compounds with AC50 equal or less than 10 uM are considered active ChEMBL. No reference
AC50 (functional) = 7.079457844 uM PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp1a2 Compounds with AC50 equal or less than 10 uM are considered active ChEMBL. No reference
AC50 (functional) = 7.943282347 uM PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp2c9 Compounds with AC50 equal or less than 10 uM are considered active ChEMBL. No reference
AC50 (functional) = 7.943282347 uM PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp3a4 Compounds with AC50 equal or less than 10 uM are considered active ChEMBL. No reference
EC50 (functional) = 0.27 um PUBCHEM_BIOASSAY: E3 Ligase dose-response_384. (Class of assay: confirmatory) [Related pubchem assays: 1444 (E3 Ligase_dose response), 1442 (E3 Ligase_dose response), 1230 (E3 Ligase HTS_1536)] ChEMBL. No reference
EC50 (functional) = 2.556 um PUBCHEM_BIOASSAY: Luminescence Cell-Based Dose Response HTS to Identify Compounds Cytotoxic to BJ-TERT RAS-Independent Fibroblast. (Class of assay: confirmatory) [Related pubchem assays: 1674 (Project Summary), 1554 (Primary HTS)] ChEMBL. No reference
EC50 (functional) = 3.401 um PUBCHEM_BIOASSAY: Luminescence Cell-Based Dose Response HTS to Identify Compounds Cytotoxic to BJ-TERT-LT-ST RAS-Independent Fibroblast. (Class of assay: confirmatory) [Related pubchem assays: 1674 (Project Summary), 1554 (Primary HTS)] ChEMBL. No reference
EC50 (functional) = 10.326 um PUBCHEM_BIOASSAY: Luminescence Cell-Based Dose Confirmation HTS to Identify Inhibitors of Heat Shock Factor 1 (HSF1). (Class of assay: confirmatory) [Related pubchem assays: 2118 (Project Summary), 2098 (Primary HTS)] ChEMBL. No reference
EC50 (functional) > 150 um PUBCHEM_BIOASSAY: Luminescence Cell-Based Dose Confirmation HTS to Identify Compounds Cytotoxic to BJeLR RAS-Dependent Fibroblast. (Class of assay: confirmatory) [Related pubchem assays: 1674 (Project Summary), 1554 (Primary HTS)] ChEMBL. No reference
IC50 (functional) = 1.73 uM PUBCHEM_BIOASSAY: XBP1 DR counterscreen for CHOP. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2732, AID493217] ChEMBL. No reference
IC50 (functional) = 4.16 uM PUBCHEM_BIOASSAY: CHOP dose-response primary assay. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2732, AID493217] ChEMBL. No reference
Potency (functional) 0.5623 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of TGF-b. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588856, AID588860] ChEMBL. No reference
Potency (functional) 1.4716 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) = 2.2387 um PUBCHEM_BIOASSAY: qHTS Assay for Modulators of Lamin A Splicing. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 2.5119 um PUBCHEM_BIOASSAY: qHTS Assay for Antagonists of the Neuropeptide S Receptor: cAMP Signal Transduction. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 2.8184 uM PUBCHEM_BIOASSAY: qHTS for Inducers of the Endoplasmic Reticulum Stress Response (ERSR) in Human Glioma: qHTS. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 3.1623 uM PubChem BioAssay. qHTS for Activators of Integrin-Mediated Alleviation for Muscular Dystrophy. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 3.2643 uM PubChem BioAssay. A quantitative high throughput screen for small molecules that induce DNA re-replication in MCF 10a normal breast cells. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 3.2643 uM PubChem BioAssay. A quantitative high throughput screen for small molecules that induce DNA re-replication in SW480 colon adenocarcinoma cells. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 3.5481 um PUBCHEM_BIOASSAY: qHTS for inhibitors of ROR gamma transcriptional activity. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 3.5481 uM PubChem BioAssay. qHTS for Inhibitors of ATXN expression. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 5.0119 um PUBCHEM_BIOASSAY: VP16 counterscreen qHTS for inhibitors of ROR gamma transcriptional activity. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 5.0119 uM PubChem BioAssay. qHTS for induction of synthetic lethality in tumor cells producing 2HG: qHTS for the HT-1080-NT fibrosarcoma cell line. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 5.6234 um PUBCHEM_BIOASSAY: qHTS Assay for Rab9 Promoter Activators. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 5.6234 uM PubChem BioAssay. qHTS of Nrf2 Activators. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 6.2733 uM PubChem BioAssay. qHTS for inhibitors of Vif-A3F interactions: Cherry picks. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 6.2733 uM PubChem BioAssay. qHTS for inhibitors of Vif-A3F interactions: Cherry picks counterscreen. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 7.9433 uM PubChem BioAssay. qHTS for Inhibitors of Vif-A3G Interactions: qHTS. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 8.8612 uM PubChem BioAssay. qHTS for inhibitors of Vif-A3G interactions: Cherry picks counterscreen. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 9.1962 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of binding or entry into cells for Lassa Virus. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID463114, AID540249] ChEMBL. No reference
Potency (functional) 11.2202 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of TGF-b: Cytotox Counterscreen. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588855, AID588860] ChEMBL. No reference
Potency (functional) 11.6891 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 14.1254 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Iota. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588623] ChEMBL. No reference
Potency (functional) 16.3601 uM PUBCHEM_BIOASSAY: qHTS screen for small molecules that inhibit ELG1-dependent DNA repair in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493107, AID493125] ChEMBL. No reference
Potency (functional) 19.9526 uM PUBCHEM_BIOASSAY: Inhibitors of the vitamin D receptor (VDR): qHTS. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504855] ChEMBL. No reference
Potency (functional) = 22.3872 um PUBCHEM_BIOASSAY: qHTS for Inhibitors of Tau Fibril Formation, Fluorescence Polarization. (Class of assay: confirmatory) [Related pubchem assays: 596 ] ChEMBL. No reference
Potency (binding) = 25.1189 um PUBCHEM_BIOASSAY: qHTS for Inhibitors of Tau Fibril Formation, Thioflavin T Binding. (Class of assay: confirmatory) [Related pubchem assays: 596 ] ChEMBL. No reference
Potency (functional) 26.0176 uM PUBCHEM_BIOASSAY: Immunofluorescence assay for KAP-1 phosphorylation on Ser824 for Identifying a Potential Treatment of Ataxia-Telangiectasia: Hit Validation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID485356] ChEMBL. No reference
Potency (functional) 26.0176 uM PUBCHEM_BIOASSAY: qHTS Assay for Identifying a Potential Treatment of Ataxia-Telangiectasia: Hit Validation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID485356] ChEMBL. No reference
Potency (binding) = 28.1838 um PUBCHEM_BIOASSAY: qHTS Assay for Identification of Novel General Anesthetics. In this assay, a GABAergic mimetic model system, apoferritin and a profluorescent 1-aminoanthracene ligand (1-AMA), was used to construct a competitive binding assay for identification of novel general anesthetics (Class of assay: confirmatory) [Related pubchem assays: 2385 (Probe Development Summary for Identification of Novel General Anesthetics), 2323 (Validation apoferritin assay run on SigmaAldrich LOPAC1280 collection)] ChEMBL. No reference
Potency (functional) 29.0929 uM PUBCHEM_BIOASSAY: Nrf2 qHTS screen for inhibitors. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493153, AID493163, AID504648] ChEMBL. No reference
Potency (functional) = 31.6228 um PUBCHEM_BIOASSAY: qHTS Assay for Promiscuous and Specific Inhibitors of Cruzain (without detergent). (Class of assay: confirmatory) [Related pubchem assays: 2158 (Confirmation qHTS Assay for Inhibitors of Cruzain), 2249 (Probe Development Summary of Promiscuous Inhibitors (Artifacts) of Cruzain), 2161 (qHTS Assay for Inhibitors of Papain: Counterscreen for Cruzain Assay), 1478 (qHTS Assay for Promiscuous and Specific Inhibitors of Cruzain (with detergent))] ChEMBL. No reference
Potency (functional) 31.6228 uM PubChem BioAssay. qHTS Assay to Identify Small Molecule Activators of BRCA1 Expression. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 35.4813 um PUBCHEM_BIOASSAY: qHTS Multiplex Assay to Identify Dual Action Probes in a Cell Model of Huntington: Aggregate Formation (GFP). (Class of assay: confirmatory) [Related pubchem assays: 1482, 1471 ] ChEMBL. No reference
Potency (functional) = 35.4813 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1). (Class of assay: confirmatory) [Related pubchem assays: 1030 (qHTS Validation Assay for Inhibitors of aldehyde dehydrogenase 1 (ALDH1A1))] ChEMBL. No reference
Potency (functional) 79.4328 uM PUBCHEM_BIOASSAY: Inhibitors of Regulator of G Protein Signaling (RGS) 4: qHTS. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504856] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23
Homo sapiens ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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