Detailed information for compound 1489991

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 719.182 | Formula: C35H32ClFN6O6S
  • H donors: 1 H acceptors: 4 LogP: 4.66 Rotable bonds: 9
    Rule of 5 violations (Lipinski): 2
  • SMILES: Clc1ccc(cc1)c1ccc(o1)/C=C/C(=O)N1CCN(CC1)c1ccc(cc1F)N1C[C@@H](OC1=O)CNC1=NS(=O)(=O)c2c(N1C)cccc2
  • InChi: 1S/C35H32ClFN6O6S/c1-40-30-4-2-3-5-32(30)50(46,47)39-34(40)38-21-27-22-43(35(45)49-27)25-10-13-29(28(37)20-25)41-16-18-42(19-17-41)33(44)15-12-26-11-14-31(48-26)23-6-8-24(36)9-7-23/h2-15,20,27H,16-19,21-22H2,1H3,(H,38,39)/b15-12+/t27-/m0/s1
  • InChiKey: KHQGJEITWBGBCM-RHHPEKOXSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis CAMK family protein kinase 0.0059 0.0051 0.0691
Entamoeba histolytica protein kinase, putative 0.0075 0.0095 0.0312
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.2145 0.5761 0.5761
Brugia malayi Stress-activated protein kinase jnk-1 0.0254 0.0583 0.0582
Loa Loa (eye worm) hypothetical protein 0.0093 0.0142 0.0141
Trichomonas vaginalis CAMK family protein kinase 0.0118 0.0211 0.3247
Brugia malayi Protein kinase domain containing protein 0.0155 0.0313 0.0312
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.013 0.0245 0.0244
Echinococcus granulosus Vam6:Vps39 protein 0.011 0.019 0.0189
Schistosoma mansoni serine/threonine protein kinase 0.0086 0.0124 0.0178
Echinococcus granulosus Diacylglycerol kinase theta 0.0041 0.0001 0.0001
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.2145 0.5761 0.5761
Schistosoma mansoni nAChR subunit 0.2145 0.5761 0.8259
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.2145 0.5761 0.8259
Entamoeba histolytica cell division protein kinase 2, putative 0.011 0.0191 0.0633
Trichomonas vaginalis CAMK family protein kinase 0.026 0.0599 0.9421
Loa Loa (eye worm) hypothetical protein 0.0085 0.012 0.0119
Echinococcus granulosus STE20 serine:threonine protein kinase 0.048 0.1203 0.1203
Entamoeba histolytica PH domain containing protein kinase, putative 0.0071 0.0084 0.0277
Echinococcus multilocularis aurora kinase A 0.0081 0.0111 0.011
Trypanosoma brucei casein kinase I, isoform 2 0.01 0.0163 0.2486
Schistosoma mansoni tyrosine kinase 0.0068 0.0074 0.0106
Giardia lamblia Kinase, AGC PKA 0.0065 0.0067 0.1015
Schistosoma mansoni diacylglycerol kinase theta 0.0041 0.0001 0.0002
Schistosoma mansoni serine/threonine protein kinase 0.0226 0.0508 0.0729
Entamoeba histolytica protein kinase, putative 0.0078 0.0102 0.0338
Loa Loa (eye worm) hypothetical protein 0.0042 0.0004 0.0003
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0341 0.0821 0.082
Entamoeba histolytica protein kinase domain containing protein 0.0081 0.0111 0.0367
Schistosoma mansoni neurotransmitter gated ion channel 0.1136 0.2999 0.4299
Brugia malayi Immunoglobulin I-set domain containing protein 0.0118 0.0212 0.0211
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0122 0.0222 0.0221
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0421 0.104 0.1039
Leishmania major protein kinase A catalytic subunit 0.0065 0.0067 0.1015
Toxoplasma gondii histone kinase SNF1, putative 0.0059 0.0051 0.0804
Brugia malayi hypothetical protein 0.0212 0.0469 0.0468
Leishmania major protein kinase, putative 0.0081 0.0111 0.1754
Echinococcus granulosus Glutaredoxin protein 5 0.0122 0.0222 0.0221
Trypanosoma brucei Casein kinase II 0.0092 0.014 0.2119
Schistosoma mansoni serine/threonine-protein kinase 0.0154 0.0309 0.0444
Echinococcus multilocularis cyclin dependent kinase 1 0.011 0.0191 0.019
Echinococcus granulosus protein kinase shaggy 0.012 0.0217 0.0217
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0136 0.0261 0.026
Echinococcus granulosus serine/threonine protein kinase 0.0154 0.0309 0.0309
Trypanosoma cruzi casein kinase, putative 0.01 0.0163 0.2639
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0065 0.0067 0.1015
Loa Loa (eye worm) CAMK/PHK protein kinase 0.0155 0.0313 0.0312
Schistosoma mansoni nAChR subunit 0.2145 0.5761 0.8259
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0078 0.0102 0.0101
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0145 0.0285 0.4592
Echinococcus multilocularis casein kinase I alpha 0.01 0.0163 0.0162
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.2145 0.5761 0.5761
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.015 0.0299 0.0298
Brugia malayi Protein kinase domain containing protein 0.0054 0.0037 0.0036
Trypanosoma cruzi casein kinase, delta isoform, putative 0.01 0.0163 0.2639
Schistosoma mansoni serine/threonine protein kinase 0.0047 0.0018 0.0026
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.1009 0.2651 0.265
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0078 0.0102 0.0101
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0065 0.0067 0.0066
Schistosoma mansoni serine/threonine protein kinase 0.0047 0.0018 0.0026
Echinococcus multilocularis casein kinase I alpha 0.01 0.0163 0.0162
Echinococcus multilocularis mitogen activated protein kinase 14 0.015 0.0299 0.0298
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0065 0.0067 0.0066
Entamoeba histolytica protein kinase, putative 0.0081 0.0111 0.0367
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.2145 0.5761 0.5761
Echinococcus granulosus myotubularin protein 13 0.0047 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.2145 0.5761 0.5761
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0059 0.0051 0.0734
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.2145 0.5761 0.5761
Echinococcus granulosus casein kinase I delta 0.01 0.0163 0.0163
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.2145 0.5761 0.5761
Trichomonas vaginalis AGC family protein kinase 0.0145 0.0285 0.4428
Schistosoma mansoni neurotransmitter gated ion channel 0.1009 0.2651 0.38
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.026 0.0599 0.0598
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0166 0.0343 0.0342
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.1009 0.2651 0.265
Giardia lamblia Kinase, CAMK CAMKL 0.0059 0.0051 0.0734
Brugia malayi hypothetical protein 0.1009 0.2651 0.265
Loa Loa (eye worm) hypothetical protein 0.1136 0.2999 0.2998
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0345 0.0832 0.0831
Entamoeba histolytica protein kinase domain containing protein 0.013 0.0245 0.0814
Schistosoma mansoni serine/threonine protein kinase 0.0228 0.0512 0.0734
Echinococcus multilocularis glycine receptor subunit beta 0.2145 0.5761 0.5761
Echinococcus granulosus serine:threonine protein kinase N2 0.0273 0.0635 0.0635
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.1136 0.2999 0.2998
Onchocerca volvulus Serine\/threonine kinase homolog 0.0155 0.0313 0.0309
Loa Loa (eye worm) hypothetical protein 0.1009 0.2651 0.265
Giardia lamblia Kinase, CMGC DYRK 0.013 0.0245 0.402
Schistosoma mansoni serine/threonine protein kinase 0.0463 0.1156 0.1657
Entamoeba histolytica protein kinase domain containing protein 0.0114 0.02 0.0664
Schistosoma mansoni protein kinase 0.01 0.0163 0.0234
Trichomonas vaginalis CMGC family protein kinase 0.0092 0.014 0.2119
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.012 0.0217 0.3503
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0355 0.0859 0.0858
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0065 0.0067 0.0067
Echinococcus multilocularis STE20 serine:threonine protein kinase 0.048 0.1203 0.1202
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0145 0.0285 0.0284
Plasmodium falciparum calcium-dependent protein kinase 1 0.0093 0.0142 0.4733
Brugia malayi serine/threonine-protein kinase 6 0.0081 0.0111 0.011
Loa Loa (eye worm) hypothetical protein 0.1136 0.2999 0.2998
Schistosoma mansoni serine/threonine protein kinase 0.011 0.0191 0.0274
Loa Loa (eye worm) CMGC/GSK protein kinase 0.012 0.0217 0.0216
Giardia lamblia Kinase, CMGC GSK 0.012 0.0217 0.355
Echinococcus granulosus calcium dependent protein kinase 0.0067 0.0071 0.0071
Loa Loa (eye worm) hypothetical protein 0.0059 0.0051 0.005
Schistosoma mansoni serine/threonine protein kinase 0.0059 0.0051 0.0073
Trichomonas vaginalis CAMK family protein kinase 0.0059 0.0051 0.0691
Plasmodium vivax calcium-dependent protein kinase, putative 0.0093 0.0142 0.4733
Echinococcus multilocularis nAChR subunit 0.1136 0.2999 0.2998
Trichomonas vaginalis CMGC family protein kinase 0.0092 0.014 0.2119
Trichomonas vaginalis AGC family protein kinase 0.0074 0.009 0.132
Loa Loa (eye worm) AGC/AKT protein kinase 0.0273 0.0635 0.0634
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.0106 0.0178 0.0177
Echinococcus multilocularis glycine receptor subunit alpha 1 0.2145 0.5761 0.5761
Brugia malayi serine/threonine kinase 12 0.0081 0.0111 0.011
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.2145 0.5761 0.5761
Echinococcus multilocularis casein kinase i 0.01 0.0163 0.0162
Echinococcus multilocularis cyclin dependent kinase 5 0.011 0.0191 0.019
Schistosoma mansoni serine/threonine protein kinase 0.0314 0.0747 0.1071
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0076 0.0096 0.1504
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0189 0.0406 0.0405
Echinococcus multilocularis epidermal growth factor receptor 0.0068 0.0074 0.0073
Echinococcus multilocularis Glutaredoxin protein 5 0.0122 0.0222 0.0221
Echinococcus granulosus phosphorylase kinase gamma subunit 0.0155 0.0313 0.0313
Schistosoma mansoni rap gtpase-activating protein 0.011 0.019 0.0272
Schistosoma mansoni serine/threonine protein kinase 0.0341 0.0821 0.1177
Trichomonas vaginalis CAMK family protein kinase 0.0059 0.0051 0.0691
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0076 0.0096 0.1417
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0136 0.0261 0.0261
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0225 0.0504 0.0503
Echinococcus multilocularis dual specificity 0.013 0.0245 0.0244
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0107 0.0183 0.0182
Entamoeba histolytica protein kinase, putative 0.0267 0.0619 0.206
Schistosoma mansoni serine/threonine protein kinase 0.0254 0.0583 0.0835
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0145 0.0285 0.4688
Trichomonas vaginalis CAMK family protein kinase 0.0059 0.0051 0.0691
Plasmodium falciparum calcium-dependent protein kinase 2 0.0093 0.0142 0.4733
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0065 0.0067 0.2103
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.2145 0.5761 0.5761
Echinococcus multilocularis calcium dependent protein kinase 0.0067 0.0071 0.007
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.2145 0.5761 0.5761
Loa Loa (eye worm) hypothetical protein 0.2589 0.6976 0.6976
Echinococcus multilocularis dual specificity protein kinase clk2 0.0145 0.0285 0.0284
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0145 0.0285 0.4688
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.0246 0.0563 0.0562
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.3694 1 1
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.2589 0.6976 1
Trichomonas vaginalis AGC family protein kinase 0.0151 0.0302 0.4694
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0114 0.02 0.3069
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.3694 1 1
Brugia malayi Protein kinase domain containing protein 0.0184 0.0393 0.0392
Trichomonas vaginalis CMGC family protein kinase 0.0076 0.0096 0.1417
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0093 0.0142 0.2288
Plasmodium vivax unspecified product 0.0092 0.014 0.4664
Loa Loa (eye worm) hypothetical protein 0.1009 0.2651 0.265
Entamoeba histolytica protein kinase, putative 0.0273 0.0635 0.2116
Plasmodium falciparum casein kinase 2, alpha subunit 0.0092 0.014 0.4664
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0341 0.0821 0.0821
Echinococcus granulosus cyclin dependent kinase 5 0.011 0.0191 0.0191
Loa Loa (eye worm) hypothetical protein 0.2145 0.5761 0.5761
Trichomonas vaginalis AGC family protein kinase 0.0273 0.0635 1
Brugia malayi casein kinase I 0.01 0.0163 0.0162
Loa Loa (eye worm) hypothetical protein 0.0088 0.0129 0.0128
Echinococcus granulosus fibroblast growth factor receptor 4 0.0107 0.0183 0.0182
Loa Loa (eye worm) CMGC/SRPK protein kinase 0.0075 0.0095 0.0094
Echinococcus granulosus hypothetical protein 0.0119 0.0214 0.0213
Schistosoma mansoni serine/threonine protein kinase 0.0145 0.0285 0.0409
Schistosoma mansoni protein kinase 0.0183 0.039 0.0559
Toxoplasma gondii AGC kinase 0.0065 0.0067 0.1073
Trichomonas vaginalis CMGC family protein kinase 0.011 0.0191 0.2921
Echinococcus multilocularis mitogen activated protein kinase 14 0.015 0.0299 0.0298
Loa Loa (eye worm) acetylcholine receptor protein 0.1009 0.2651 0.265
Brugia malayi Cation transporter family protein 0.2145 0.5761 0.5761
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.011 0.019 0.3079
Entamoeba histolytica protein kinase, putative 0.0114 0.02 0.0664
Onchocerca volvulus 0.2145 0.5761 0.5759
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.2145 0.5761 0.8259
Echinococcus multilocularis serine:threonine protein kinase N2 0.0128 0.0238 0.0237
Schistosoma mansoni serine/threonine protein kinase 0.0075 0.0095 0.0136
Brugia malayi Cam kinase protein 1 0.0093 0.0142 0.0141
Loa Loa (eye worm) hypothetical protein 0.2145 0.5761 0.5761
Brugia malayi RhoGAP domain containing protein 0.0046 0.0015 0.0014
Trichomonas vaginalis STE family protein kinase 0.0078 0.0102 0.1514
Schistosoma mansoni atypical protein kinase C 0.0274 0.0638 0.0915
Trichomonas vaginalis CAMK family protein kinase 0.0059 0.0051 0.0691
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0114 0.02 0.3258
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.011 0.019 0.0272
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0046 0.0015 0.0014
Schistosoma mansoni serine/threonine protein kinase 0.0093 0.0142 0.0204
Echinococcus granulosus glycine receptor subunit alpha 1 0.2145 0.5761 0.5761
Echinococcus granulosus C2 calcium dependent membrane targeting 0.0042 0.0004 0.0004
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.011 0.019 0.2901
Echinococcus multilocularis rac serine:threonine kinase 0.0154 0.0309 0.0308
Echinococcus granulosus cyclin dependent kinase 1 0.011 0.0191 0.0191
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.0047 0.0018 0.0017
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.012 0.0217 0.355
Echinococcus multilocularis serine:threonine protein kinase N2 0.0273 0.0635 0.0634
Schistosoma mansoni serine/threonine protein kinase 0.0065 0.0067 0.0097
Plasmodium falciparum glycogen synthase kinase 3 0.012 0.0217 0.736
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.2145 0.5761 0.5761
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0043 0.0007 0.0006
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0145 0.0285 0.4416
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0254 0.0583 0.0582
Brugia malayi Variant SH3 domain containing protein 0.0046 0.0015 0.0014
Echinococcus granulosus serine:threonine kinase SAD 1 0.0059 0.0051 0.0051
Loa Loa (eye worm) hypothetical protein 0.0047 0.0018 0.0017
Plasmodium falciparum protein kinase 5 0.011 0.0191 0.6429
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0059 0.0051 0.1521
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.2145 0.5761 0.5761
Entamoeba histolytica protein kinase domain containing protein 0.012 0.0217 0.0722
Trypanosoma cruzi serine/arginine-rich protein specific kinase SRPK, putative 0.0075 0.0095 0.1475
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0065 0.0067 0.0067
Echinococcus granulosus casein kinase I alpha 0.01 0.0163 0.0163
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0059 0.0051 0.005
Schistosoma mansoni nAChR subunit 0.2145 0.5761 0.8259
Plasmodium vivax tyrosine kinase-like protein, putative 0.0073 0.0089 0.286
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0074 0.009 0.0089
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.0355 0.0859 0.0858
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.1009 0.2651 0.265
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0093 0.0142 0.0141
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0107 0.0183 0.0182
Echinococcus multilocularis cyclin dependent kinase 0.011 0.0191 0.019
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.012 0.0217 0.0312
Schistosoma mansoni serine/threonine protein kinase 0.0155 0.0313 0.0448
Trichomonas vaginalis STE family protein kinase 0.0077 0.0099 0.1456
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0228 0.0512 0.0511
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0059 0.0051 0.005
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0166 0.0343 0.0343
Trichomonas vaginalis CAMK family protein kinase 0.0059 0.0051 0.0691
Schistosoma mansoni protein kinase 0.0421 0.104 0.1491
Loa Loa (eye worm) hypothetical protein 0.3694 1 1
Echinococcus granulosus Protein kinase C brain isozyme 0.0226 0.0508 0.0508
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.1136 0.2999 0.2998
Echinococcus granulosus serine:threonine protein kinase N2 0.0128 0.0238 0.0238
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0341 0.0821 0.082
Loa Loa (eye worm) hypothetical protein 0.1009 0.2651 0.265
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0046 0.0015 0.0021
Trichomonas vaginalis CMGC family protein kinase 0.0076 0.0096 0.1417
Entamoeba histolytica protein kinase, putative 0.0081 0.0111 0.0367
Entamoeba histolytica protein kinase, putative 0.0063 0.0061 0.0199
Onchocerca volvulus 0.0288 0.0676 0.0672
Brugia malayi Protein kinase domain containing protein 0.0273 0.0635 0.0634
Echinococcus multilocularis serine:threonine protein kinase 0.0106 0.0178 0.0177
Loa Loa (eye worm) hypothetical protein 0.0182 0.0386 0.0385
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.3694 1 1
Brugia malayi Casein kinase II, alpha chain 0.0092 0.014 0.0139
Onchocerca volvulus 0.012 0.0217 0.0213
Loa Loa (eye worm) hypothetical protein 0.2145 0.5761 0.5761
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0075 0.0095 0.1475
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0115 0.0203 0.3304
Echinococcus granulosus nAChR subunit 0.1136 0.2999 0.2999
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0081 0.0111 0.011
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.0191 0.0412 0.0411
Schistosoma mansoni serine/threonine protein kinase 0.0114 0.02 0.0287
Onchocerca volvulus 0.1009 0.2651 0.2647
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0047 0.0018 0.0179
Toxoplasma gondii NEK kinase 0.0043 0.0007 0.0101
Toxoplasma gondii CMGC kinase, CK2 family 0.0092 0.014 0.2256
Loa Loa (eye worm) hypothetical protein 0.1009 0.2651 0.265
Entamoeba histolytica protein kinase, putative 0.0094 0.0146 0.0483
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0341 0.0821 0.082
Loa Loa (eye worm) hypothetical protein 0.0119 0.0214 0.0213
Loa Loa (eye worm) hypothetical protein 0.1009 0.2651 0.265
Echinococcus multilocularis mitogen activated protein kinase 0.0076 0.0096 0.0095
Trypanosoma cruzi cdc2-related kinase 3 0.011 0.0191 0.3101
Brugia malayi MAP kinase sur-1 0.0076 0.0096 0.0095
Loa Loa (eye worm) AGC/PKA protein kinase 0.0065 0.0067 0.0066
Loa Loa (eye worm) casein kinase 0.0177 0.0374 0.0373
Echinococcus multilocularis unc 13 (munc13) 0.0042 0.0004 0.0003
Trichomonas vaginalis CMGC family protein kinase 0.013 0.0245 0.3787
Echinococcus granulosus c-Jun N-terminal kinases 0.0254 0.0583 0.0583
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0078 0.0102 0.0102
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0208 0.0457 0.0456
Echinococcus granulosus twitchin 0.0057 0.0045 0.0045
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0145 0.0285 0.0285
Trichomonas vaginalis CAMK family protein kinase 0.026 0.0599 0.9421
Brugia malayi Protein kinase c protein 2 0.0107 0.0182 0.0181
Schistosoma mansoni protein kinase C mu 0.0041 0.0001 0.0002
Echinococcus multilocularis serine:threonine protein kinase N2 0.0145 0.0285 0.0284
Brugia malayi cell division control protein 2 homolog 0.011 0.0191 0.019
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.2145 0.5761 0.5761
Brugia malayi intracellular kinase 0.012 0.0217 0.0216
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0059 0.0051 0.0691
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0145 0.0285 0.4688
Plasmodium vivax protein kinase Crk2 0.011 0.0191 0.6429
Schistosoma mansoni protein kinase 0.0144 0.0283 0.0406
Echinococcus granulosus glycine receptor subunit beta 0.2145 0.5761 0.5761
Echinococcus multilocularis nervana 2 0.0122 0.0222 0.0221
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0065 0.0067 0.0067
Echinococcus granulosus dual specificity 0.0114 0.02 0.02
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0138 0.0267 0.0267
Trichomonas vaginalis CAMK family protein kinase 0.0118 0.0211 0.3247
Echinococcus granulosus epidermal growth factor receptor 0.0068 0.0074 0.0074
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0093 0.0142 0.0141
Trichomonas vaginalis CAMK family protein kinase 0.0059 0.0051 0.0691
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0107 0.0183 0.0182
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.3694 1 1
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0225 0.0504 0.0504
Trichomonas vaginalis CMGC family protein kinase 0.0092 0.014 0.2119
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.1009 0.2651 0.265
Loa Loa (eye worm) hypothetical protein 0.2145 0.5761 0.5761
Giardia lamblia Kinase, AGC PKA 0.0148 0.0293 0.4824
Loa Loa (eye worm) hypothetical protein 0.1136 0.2999 0.2998
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0093 0.0142 0.2288
Onchocerca volvulus 0.0307 0.073 0.0726
Brugia malayi map kinase activated protein kinase protein 2 0.0382 0.0933 0.0932
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0228 0.0512 0.0511
Trypanosoma brucei SNF1-related protein kinases, putative 0.0059 0.0051 0.0691
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.011 0.0191 0.019
Entamoeba histolytica protein kinase, putative 0.0057 0.0044 0.0143
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0145 0.0285 0.4416
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.3694 1 1
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0187 0.0402 0.0401
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0074 0.009 0.009
Loa Loa (eye worm) hypothetical protein 0.0178 0.0375 0.0374
Echinococcus multilocularis cyclin dependent kinase 1 0.011 0.0191 0.019
Entamoeba histolytica casein kinase 1, putative 0.01 0.0163 0.0542
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0145 0.0285 0.0284
Echinococcus granulosus serine:threonine protein kinase PLK1 0.026 0.0599 0.0599
Schistosoma mansoni serine/threonine-protein kinase 0.0154 0.0309 0.0444
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0254 0.0583 0.0582
Entamoeba histolytica protein kinase, putative 0.0273 0.0635 0.2116
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0065 0.0067 0.1015
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0065 0.0067 0.0066
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0148 0.0293 0.0292
Trichomonas vaginalis CMGC family protein kinase 0.0076 0.0096 0.1417
Schistosoma mansoni serine/threonine protein kinase 0.0212 0.0469 0.0673
Schistosoma mansoni vam6/vps39 related 0.011 0.019 0.0272
Trypanosoma cruzi casein kinase, putative 0.01 0.0163 0.2639
Schistosoma mansoni tyrosine kinase 0.0058 0.0047 0.0067
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0065 0.0067 0.0956
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.011 0.0191 0.3101
Brugia malayi hypothetical protein 0.1009 0.2651 0.265
Echinococcus multilocularis glycine receptor subunit alpha 1 0.2145 0.5761 0.5761
Schistosoma mansoni tyrosine kinase 0.0068 0.0074 0.0106
Loa Loa (eye worm) TK protein kinase 0.0118 0.0212 0.0211
Echinococcus granulosus glycine receptor subunit alpha 1 0.2145 0.5761 0.5761
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0128 0.0238 0.8066
Toxoplasma gondii casein kinase I 0.01 0.0163 0.2629
Echinococcus granulosus expressed protein 0.0075 0.0095 0.0094
Schistosoma mansoni diacylglycerol kinase theta 0.0041 0.0001 0.0002
Brugia malayi Furin-like cysteine rich region family protein 0.0068 0.0074 0.0073
Giardia lamblia Kinase, NEK 0.0128 0.0238 0.3891
Echinococcus multilocularis mitogen activated protein kinase 3 0.0076 0.0096 0.0095
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0046 0.0015 0.0021
Trichomonas vaginalis CAMK family protein kinase 0.0106 0.0178 0.272
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.2589 0.6976 1
Trichomonas vaginalis CAMK family protein kinase 0.026 0.0599 0.9421
Toxoplasma gondii aurora kinase 0.0081 0.0111 0.1781
Trichomonas vaginalis CMGC family protein kinase 0.013 0.0245 0.3787
Trichomonas vaginalis CAMK family protein kinase 0.026 0.0599 0.9421
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0065 0.0067 0.0956
Entamoeba histolytica protein kinase , putative 0.0081 0.0111 0.0367
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.1136 0.2999 0.2998
Trichomonas vaginalis AGC family protein kinase 0.0273 0.0635 1
Loa Loa (eye worm) hypothetical protein 0.0137 0.0262 0.0261
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.0382 0.0933 0.0932
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.3694 1 1
Brugia malayi hypothetical protein 0.011 0.019 0.0188
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0081 0.0111 0.0111
Loa Loa (eye worm) hypothetical protein 0.1009 0.2651 0.265
Echinococcus granulosus cyclin dependent kinase 0.011 0.0191 0.0191
Schistosoma mansoni serine/threonine protein kinase 0.011 0.0191 0.0274
Echinococcus granulosus mitogen activated protein kinase 0.0076 0.0096 0.0096
Entamoeba histolytica hypothetical protein 0.1136 0.2999 1
Echinococcus multilocularis glycine receptor subunit alpha 1 0.2145 0.5761 0.5761
Brugia malayi Protein kinase domain containing protein 0.0341 0.0821 0.082
Loa Loa (eye worm) hypothetical protein 0.011 0.019 0.0188
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0031 0.0382
Schistosoma mansoni serine/threonine protein kinase 0.0076 0.0096 0.0138
Schistosoma mansoni serine/threonine protein kinase 0.0051 0.0028 0.004
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0226 0.0508 0.0507
Brugia malayi ribosomal protein S6 kinase alpha 3 0.0109 0.0186 0.0185
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0166 0.0343 0.0343
Schistosoma mansoni unc-13 (munc13) 0.0042 0.0004 0.0006
Loa Loa (eye worm) protein kinase domain-containing protein 0.0203 0.0445 0.0444
Schistosoma mansoni serine/threonine protein kinase 0.0382 0.0933 0.1337
Trichomonas vaginalis CAMK family protein kinase 0.026 0.0599 0.9421
Brugia malayi protein kinase C3,putative 0.0149 0.0296 0.0295
Brugia malayi Cation transporter family protein 0.2589 0.6976 0.6976
Trypanosoma brucei polo-like protein kinase 0.026 0.0599 0.9421
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0076 0.0096 0.1504
Echinococcus granulosus glycine receptor subunit alpha 1 0.2145 0.5761 0.5761
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.1009 0.2651 0.265
Schistosoma mansoni hypothetical protein 0.011 0.019 0.0272
Trypanosoma brucei STE20-like serine/threonine-protein kinase 1, putative 0.0077 0.0099 0.1456
Echinococcus granulosus casein kinase i 0.01 0.0163 0.0163
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0093 0.0142 0.4733
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.1009 0.2651 0.265
Echinococcus granulosus unc 13 munc13 0.0042 0.0004 0.0004
Schistosoma mansoni nAChR subunit 0.2145 0.5761 0.8259
Schistosoma mansoni serine/threonine protein kinase 0.01 0.0163 0.0234
Onchocerca volvulus 0.011 0.019 0.0185
Giardia lamblia Kinase, CAMK CAMKL 0.0059 0.0051 0.0734
Schistosoma mansoni tyrosine kinase 0.0138 0.0267 0.0383
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.0435 0.1079 0.1078
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0046 0.0015 0.0014
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0076 0.0096 0.1542
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0092 0.014 0.0139
Trichomonas vaginalis CAMK family protein kinase 0.0093 0.0142 0.2151
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.2145 0.5761 0.5761
Loa Loa (eye worm) hypothetical protein 0.0228 0.0513 0.0512
Schistosoma mansoni protein kinase C mu 0.0208 0.0457 0.0655
Toxoplasma gondii AGC kinase 0.0065 0.0067 0.1073
Echinococcus granulosus nAChR subunit 0.2145 0.5761 0.5761
Brugia malayi STE20-like kinase MST 0.0246 0.0563 0.0562
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0145 0.0285 0.0284
Brugia malayi Protein kinase domain containing protein 0.0074 0.009 0.0089
Schistosoma mansoni kinase 0.0278 0.0649 0.093
Plasmodium vivax serine/threonine kinase-1, putative 0.0145 0.0285 0.9718
Loa Loa (eye worm) TK/EGFR protein kinase 0.0068 0.0074 0.0073
Brugia malayi Protein kinase domain containing protein 0.011 0.0191 0.019
Onchocerca volvulus 0.2145 0.5761 0.5759
Echinococcus granulosus Rac GTPase activating protein 1 0.0041 0.0001 0.0001
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.011 0.0191 0.0191
Loa Loa (eye worm) hypothetical protein 0.2145 0.5761 0.5761
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.1009 0.2651 0.265
Echinococcus multilocularis dual specificity 0.0114 0.02 0.0199
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.2145 0.5761 0.5761
Entamoeba histolytica protein kinase, putative 0.0114 0.02 0.0664
Brugia malayi phosphoinositide-dependent protein kinase I 0.0074 0.009 0.0089
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.1009 0.2651 0.265
Entamoeba histolytica PH domain containing protein kinase, putative 0.0071 0.0084 0.0277
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0065 0.0067 0.1015
Plasmodium falciparum calcium-dependent protein kinase 3 0.0093 0.0142 0.4733
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.0921 0.2409 0.2408
Brugia malayi Protein kinase domain containing protein 0.0145 0.0285 0.0284
Plasmodium vivax glycogen synthase kinase 3, putative 0.012 0.0217 0.736
Onchocerca volvulus 0.1136 0.2999 0.2996
Schistosoma mansoni nAChR subunit 0.2145 0.5761 0.8259
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.2145 0.5761 0.5761
Echinococcus granulosus NDR protein kinase 0.0145 0.0285 0.0285
Brugia malayi Protein kinase domain 0.0078 0.0102 0.0101
Onchocerca volvulus 0.1136 0.2999 0.2996
Schistosoma mansoni serine/threonine protein kinase 0.0059 0.0051 0.0073
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0421 0.104 0.104
Echinococcus multilocularis nervana 2 0.0122 0.0222 0.0221
Schistosoma mansoni serine/threonine protein kinase 0.0203 0.0445 0.0638
Onchocerca volvulus 0.2589 0.6976 0.6975
Loa Loa (eye worm) hypothetical protein 0.1136 0.2999 0.2998
Echinococcus granulosus casein kinase I alpha 0.01 0.0163 0.0163
Trichomonas vaginalis STE family protein kinase 0.0078 0.0102 0.1514
Plasmodium vivax serine/threonine protein kinase, putative 0.0075 0.0095 0.3058
Onchocerca volvulus 0.2589 0.6976 0.6975
Brugia malayi Protein kinase domain containing protein 0.0106 0.0178 0.0177
Loa Loa (eye worm) AGC/NDR protein kinase 0.0145 0.0285 0.0284
Leishmania major protein kinase, putative 0.0145 0.0285 0.4688
Loa Loa (eye worm) CMGC/GSK protein kinase 0.012 0.0217 0.0216
Echinococcus multilocularis epidermal growth factor receptor 0.0068 0.0074 0.0073
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0093 0.0142 0.0141
Entamoeba histolytica protein kinase domain containing protein 0.0092 0.014 0.0465
Trichomonas vaginalis CK1 family protein kinase 0.01 0.0163 0.2486
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0068 0.0074 0.0074
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.026 0.0599 1
Giardia lamblia Aurora kinase 0.0081 0.0111 0.1754
Brugia malayi Doublecortin family protein 0.0142 0.0277 0.0276
Trypanosoma brucei protein kinase, putative 0.012 0.0217 0.3345
Loa Loa (eye worm) hypothetical protein 0.1009 0.2651 0.265
Loa Loa (eye worm) AGC/PKA protein kinase 0.0065 0.0067 0.0066
Echinococcus granulosus insulin receptor 0.0138 0.0267 0.0267
Schistosoma mansoni serine/threonine protein kinase 0.0145 0.0285 0.0408
Schistosoma mansoni serine/threonine protein kinase 0.0086 0.0124 0.0178
Brugia malayi hypothetical protein 0.1009 0.2651 0.265
Schistosoma mansoni protein kinase 0.0254 0.0584 0.0838
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.015 0.0299 0.4938
Echinococcus granulosus protein kinase c epsilon type 0.0187 0.0402 0.0401
Loa Loa (eye worm) STE/STE20/SLK protein kinase 0.0183 0.039 0.0389
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0155 0.0312 0.0311
Brugia malayi serine/threonine protein kinase 6 0.0081 0.0111 0.011
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0148 0.0293 1
Trichomonas vaginalis CK1 family protein kinase 0.01 0.0163 0.2486
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.2145 0.5761 0.5761
Schistosoma mansoni serine/threonine protein kinase 0.0059 0.0051 0.0073
Echinococcus multilocularis phosphorylase kinase gamma subunit 0.0155 0.0313 0.0312
Leishmania major protein kinase, putative 0.0077 0.0099 0.1546
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.1009 0.2651 0.265
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.026 0.0599 0.0598
Echinococcus multilocularis dual specificity 0.013 0.0245 0.0244
Echinococcus granulosus glycine receptor subunit beta 0.2145 0.5761 0.5761
Loa Loa (eye worm) ACC-1 protein 0.2145 0.5761 0.5761
Echinococcus granulosus serine:threonine protein kinase 3 0.0246 0.0563 0.0563
Trichomonas vaginalis CMGC family protein kinase 0.0092 0.014 0.2119
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.2145 0.5761 0.5761
Trichomonas vaginalis CMGC family protein kinase 0.011 0.0191 0.2921
Plasmodium falciparum casein kinase 1 0.01 0.0163 0.5471
Plasmodium falciparum serine/threonine protein kinase, putative 0.0081 0.0111 0.3636
Onchocerca volvulus 0.01 0.0163 0.0159
Plasmodium falciparum calcium-dependent protein kinase 4 0.0093 0.0142 0.4733
Trichomonas vaginalis CAMK family protein kinase 0.0059 0.0051 0.0691
Schistosoma mansoni nAChR subunit 0.2145 0.5761 0.8259
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0341 0.0821 0.082
Trypanosoma cruzi casein kinase, putative 0.01 0.0163 0.2639
Onchocerca volvulus 0.0182 0.0386 0.0382
Schistosoma mansoni serine/threonine protein kinase 0.0043 0.0007 0.0011
Loa Loa (eye worm) hypothetical protein 0.1136 0.2999 0.2998
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.011 0.0191 0.019
Schistosoma mansoni nAChR subunit 0.2145 0.5761 0.8259
Schistosoma mansoni serine/threonine protein kinase 0.026 0.0599 0.0859
Echinococcus multilocularis N chimaerin 0.0046 0.0015 0.0014
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0093 0.0142 0.0142
Giardia lamblia Kinase, CMGC CDK 0.011 0.0191 0.3101
Schistosoma mansoni protein kinase 0.0078 0.0102 0.0147
Schistosoma mansoni tyrosine kinase 0.0138 0.0267 0.0383
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0145 0.0285 0.0285
Echinococcus granulosus calcium activated potassium channel 0.0086 0.0124 0.0124
Loa Loa (eye worm) hypothetical protein 0.0065 0.0067 0.0066
Echinococcus granulosus serine threonine protein kinase nrc 0.0148 0.0293 0.0293
Giardia lamblia Kinase, NEK 0.0128 0.0238 0.3891
Schistosoma mansoni protein kinase C 0.0042 0.0004 0.0006
Plasmodium falciparum tyrosine kinase-like protein, putative 0.0073 0.0089 0.286
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.0086 0.0124 0.0123
Trichomonas vaginalis AGC family protein kinase 0.0065 0.0067 0.0956
Trypanosoma cruzi aurora B kinase, putative 0.0081 0.0111 0.1754
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.0212 0.0469 0.0468
Loa Loa (eye worm) hypothetical protein 0.1136 0.2999 0.2998
Trichomonas vaginalis CK1 family protein kinase 0.01 0.0163 0.2486
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0166 0.0343 0.0342
Echinococcus multilocularis myosin iiia 0.0077 0.0099 0.0098
Schistosoma mansoni serine/threonine protein kinase 0.0187 0.0402 0.0576
Onchocerca volvulus Serine\/threonine kinase homolog 0.026 0.0599 0.0595
Echinococcus multilocularis nAChR subunit 0.2145 0.5761 0.5761
Brugia malayi probable protein kinase 0.0254 0.0584 0.0583
Giardia lamblia Kinase, CMGC CDK 0.011 0.0191 0.3101
Echinococcus granulosus casein kinase I alpha 0.01 0.0163 0.0163
Giardia lamblia Kinase, NEK 0.0128 0.0238 0.3891
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0093 0.0142 0.2151
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.3694 1 1
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.011 0.0191 0.019
Loa Loa (eye worm) TK/INSR protein kinase 0.0138 0.0267 0.0266
Leishmania major casein kinase II, putative 0.0092 0.014 0.225
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.0382 0.0933 0.0932
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0059 0.0051 0.0051
Echinococcus multilocularis hypothetical protein 0.006 0.0053 0.0052
Schistosoma mansoni tyrosine kinase 0.0068 0.0074 0.0106
Brugia malayi Fes/CIP4 homology domain containing protein 0.0071 0.0082 0.0081
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0093 0.0142 0.0142
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0078 0.0102 0.0102
Toxoplasma gondii AGC kinase 0.0267 0.0619 1
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0148 0.0293 1
Echinococcus multilocularis 0.0119 0.0214 0.0213
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.015 0.0299 0.4652
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0191 0.0412 0.0411
Brugia malayi Protein kinase domain containing protein 0.0203 0.0445 0.0444
Echinococcus granulosus epidermal growth factor receptor 0.0068 0.0074 0.0074
Loa Loa (eye worm) hypothetical protein 0.1136 0.2999 0.2998
Trichomonas vaginalis CAMK family protein kinase 0.0059 0.0051 0.0691
Brugia malayi Protein kinase domain containing protein 0.0081 0.0109 0.0108
Entamoeba histolytica protein kinase, putative 0.012 0.0217 0.0722
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0093 0.0142 0.4733
Schistosoma mansoni serine/threonine protein kinase 0.0273 0.0635 0.091
Schistosoma mansoni acetylcholine receptor subunit beta 0.1009 0.2651 0.38
Leishmania major protein kinase, putative 0.0093 0.0142 0.2283
Schistosoma mansoni serine/threonine protein kinase 0.0166 0.0343 0.0492
Echinococcus granulosus rho-associated protein kinase 1 0.0314 0.0747 0.0747
Brugia malayi hypothetical protein 0.1009 0.2651 0.265
Trypanosoma cruzi cdc2-related kinase 1 0.011 0.0191 0.3101
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0114 0.02 0.3258
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0093 0.0142 0.2288
Loa Loa (eye worm) hypothetical protein 0.0106 0.0178 0.0177
Echinococcus granulosus raf serine:threonine protein kinase 0.0051 0.0028 0.0028
Brugia malayi Protein kinase domain containing protein 0.0435 0.1079 0.1078
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.2145 0.5761 0.5761
Trichomonas vaginalis AGC family protein kinase 0.0145 0.0285 0.4428
Toxoplasma gondii NEK kinase 0.0043 0.0007 0.0101
Giardia lamblia Kinase, CMGC CK2 0.0092 0.014 0.225
Loa Loa (eye worm) hypothetical protein 0.0141 0.0273 0.0272
Schistosoma mansoni serine/threonine protein kinase 0.0145 0.0285 0.0408
Trichomonas vaginalis CMGC family protein kinase 0.0092 0.014 0.2119
Entamoeba histolytica serine/threonine protein kinase, putative 0.0059 0.0051 0.0166
Echinococcus multilocularis casein kinase I delta 0.01 0.0163 0.0162
Schistosoma mansoni nAChR subunit 0.1009 0.2651 0.38
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.0191 0.0412 0.0411
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.2145 0.5761 0.5761
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0093 0.0142 0.0141
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.0212 0.0469 0.0468
Loa Loa (eye worm) hypothetical protein 0.1009 0.2651 0.265
Brugia malayi serine/threonine-protein kinase PAK 7 0.0222 0.0496 0.0495
Trichomonas vaginalis CMGC family protein kinase 0.0076 0.0096 0.1417
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.2145 0.5761 0.5761
Trichomonas vaginalis CAMK family protein kinase 0.0086 0.0124 0.1861
Entamoeba histolytica protein kinase, putative 0.0093 0.0142 0.0471
Giardia lamblia Kinase, CMGC CLK 0.0145 0.0285 0.4688
Toxoplasma gondii NEK kinase 0.0043 0.0007 0.0101
Echinococcus granulosus serine:threonine protein kinase 0.0106 0.0178 0.0178
Brugia malayi p21/Cdc42/Rac1-activated kinase 0.0047 0.0018 0.0017
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.013 0.0245 0.0244
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0077 0.0099 0.1546
Loa Loa (eye worm) hypothetical protein 0.0117 0.0209 0.0208
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0065 0.0067 0.0066
Loa Loa (eye worm) hypothetical protein 0.2145 0.5761 0.5761
Plasmodium falciparum NIMA related kinase 1 0.0128 0.0238 0.8066
Loa Loa (eye worm) LGC-31 protein 0.2145 0.5761 0.5761
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.01 0.0163 0.0162
Echinococcus multilocularis protein kinase c epsilon type 0.0187 0.0402 0.0401
Brugia malayi serine/threonine-protein kinase plk-2 0.026 0.0599 0.0598
Brugia malayi Protein kinase domain containing protein 0.0138 0.0267 0.0266
Trichomonas vaginalis CAMK family protein kinase 0.0059 0.0051 0.0691
Brugia malayi p70 ribosomal S6 kinase beta 0.0267 0.0619 0.0618
Schistosoma mansoni serine/threonine protein kinase 0.0166 0.0343 0.0492
Plasmodium falciparum serine/threonine protein kinase 0.0075 0.0095 0.3058
Brugia malayi Protein kinase domain containing protein 0.0086 0.0124 0.0123
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0076 0.0096 0.1504
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0076 0.0096 0.0095
Trypanosoma cruzi casein kinase II, putative 0.0092 0.014 0.225
Brugia malayi Protein kinase domain containing protein 0.0114 0.02 0.0199
Trichomonas vaginalis CMGC family protein kinase 0.0092 0.014 0.2119
Loa Loa (eye worm) hypothetical protein 0.1009 0.2651 0.265
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0066 0.007 0.0069
Schistosoma mansoni serine/threonine protein kinase 0.013 0.0245 0.0351
Echinococcus granulosus protein kinase C gamma type 0.0185 0.0396 0.0396
Loa Loa (eye worm) hypothetical protein 0.2145 0.5761 0.5761
Leishmania major protein kinase, putative 0.0145 0.0285 0.4688
Loa Loa (eye worm) camk/dcamkl protein kinase 0.0142 0.0277 0.0276
Entamoeba histolytica casein kinase, putative 0.0092 0.014 0.0465
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0136 0.0261 0.026
Loa Loa (eye worm) hypothetical protein 0.1009 0.2651 0.265
Entamoeba histolytica PH domain containing protein kinase, putative 0.0154 0.0309 0.1029
Onchocerca volvulus Putative nachr subunit 0.3694 1 1
Loa Loa (eye worm) hypothetical protein 0.0188 0.0403 0.0402
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0093 0.0142 0.0141
Trichomonas vaginalis AGC family protein kinase 0.0145 0.0285 0.4428
Trypanosoma brucei serine/arginine-rich protein specific kinase SRPK, putative 0.0075 0.0095 0.139
Plasmodium falciparum protein serine/threonine kinase-1 0.0145 0.0285 0.9718
Echinococcus granulosus serine:threonine protein kinase mig 15 0.0228 0.0513 0.0513
Trichomonas vaginalis CAMK family protein kinase 0.0059 0.0051 0.0691
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.0144 0.0283 0.0282
Echinococcus multilocularis glycine receptor subunit beta 0.2145 0.5761 0.5761
Echinococcus granulosus nervana 2 0.0122 0.0222 0.0221
Trypanosoma cruzi Protein kinase B 0.0154 0.0309 0.5106
Onchocerca volvulus 0.2145 0.5761 0.5759
Brugia malayi P38 map kinase family protein 2 0.015 0.0299 0.0298
Schistosoma mansoni protein kinase 0.0189 0.0406 0.0581
Echinococcus granulosus casein kinase I delta 0.01 0.0163 0.0163
Echinococcus granulosus protein kinase c iota type 0.0268 0.0622 0.0621
Brugia malayi putative serine/threonine kinase SADA gamma 0.0059 0.0051 0.005
Entamoeba histolytica protein kinase, putative 0.0145 0.0285 0.0949
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0092 0.014 0.4664
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.2145 0.5761 0.5761
Echinococcus granulosus casein kinase I gamma 0.0203 0.0445 0.0445
Echinococcus granulosus aurora kinase A 0.0081 0.0111 0.0111
Onchocerca volvulus 0.0188 0.0403 0.0398
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0119 0.0214 0.3296
Echinococcus granulosus N chimaerin 0.0046 0.0015 0.0014
Echinococcus multilocularis protein kinase c iota type 0.0268 0.0622 0.0621
Echinococcus granulosus casein kinase ii subunit alpha 0.0092 0.014 0.014
Schistosoma mansoni serine/threonine kinase 0.0086 0.0124 0.0178
Trichomonas vaginalis CAMK family protein kinase 0.0059 0.0051 0.0691
Trypanosoma brucei cdc2-related kinase 1 0.011 0.0191 0.2921
Onchocerca volvulus 0.0141 0.0273 0.0269
Schistosoma mansoni serine/threonine protein kinase 0.0059 0.0051 0.0073
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0355 0.0859 0.0859
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0078 0.0102 0.0102
Entamoeba histolytica cell division protein kinase 2, putative 0.011 0.0191 0.0633
Brugia malayi Protein kinase domain containing protein 0.0075 0.0095 0.0094
Trypanosoma cruzi polo-like protein kinase, putative 0.026 0.0599 1
Loa Loa (eye worm) AUR protein kinase 0.0081 0.0111 0.011
Loa Loa (eye worm) hypothetical protein 0.011 0.019 0.0188
Trichomonas vaginalis CAMK family protein kinase 0.0059 0.0051 0.0691
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0059 0.0051 0.005
Loa Loa (eye worm) hypothetical protein 0.2145 0.5761 0.5761
Schistosoma mansoni protein kinase 0.0421 0.104 0.1491
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0341 0.0821 0.0817
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0138 0.0267 0.0266
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0076 0.0096 0.1504
Entamoeba histolytica protein kinase, putative 0.0063 0.0061 0.0199
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.032 0.0764 0.0763
Schistosoma mansoni protein kinase 0.0355 0.0859 0.1231
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0065 0.0067 0.1015
Loa Loa (eye worm) hypothetical protein 0.0141 0.0273 0.0272
Echinococcus granulosus dual specificity 0.013 0.0245 0.0245
Schistosoma mansoni serine/threonine protein kinase 0.0191 0.0412 0.059
Echinococcus multilocularis calcium activated potassium channel 0.0086 0.0124 0.0123
Loa Loa (eye worm) hypothetical protein 0.1009 0.2651 0.265
Plasmodium falciparum calcium-dependent protein kinase 5 0.0093 0.0142 0.4733
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.011 0.019 0.0189
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.2145 0.5761 0.5761
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0093 0.0142 0.0142
Brugia malayi Cation transporter family protein 0.2145 0.5761 0.5761
Schistosoma mansoni rac gtpase activating protein 0.0041 0.0001 0.0002
Loa Loa (eye worm) AGC/PKN protein kinase 0.0273 0.0635 0.0634
Echinococcus multilocularis mitogen activated protein kinase 11 0.015 0.0299 0.0298
Entamoeba histolytica p21-activated kinase 0.0084 0.0119 0.0394
Schistosoma mansoni serine/threonine protein kinase 0.0225 0.0504 0.0722
Brugia malayi Temporarily assigned gene name protein 59 0.011 0.019 0.0188
Schistosoma mansoni serine/threonine protein kinase 0.0226 0.0508 0.0729
Loa Loa (eye worm) hypothetical protein 0.2145 0.5761 0.5761
Trichomonas vaginalis CAMK family protein kinase 0.026 0.0599 0.9421
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0081 0.0111 0.3636
Leishmania major protein kinase A catalytic subunit isoform 1 0.0065 0.0067 0.1015
Trichomonas vaginalis CMGC family protein kinase 0.0092 0.014 0.2119
Trichomonas vaginalis STE family protein kinase 0.0128 0.0238 0.3665
Schistosoma mansoni serine/threonine protein kinase 0.0074 0.009 0.0129
Loa Loa (eye worm) hypothetical protein 0.0137 0.0262 0.0261
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.1136 0.2999 0.2998
Trichomonas vaginalis CAMK family protein kinase 0.026 0.0599 0.9421
Trichomonas vaginalis CMGC family protein kinase 0.012 0.0217 0.3345
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.0059 0.0051 0.0734
Trichomonas vaginalis CMGC family protein kinase 0.013 0.0245 0.3787
Loa Loa (eye worm) hypothetical protein 0.0052 0.0031 0.003
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0122 0.0222 0.0221
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0167 0.0344 0.0343
Echinococcus granulosus serine:threonine protein kinase 0.0106 0.0178 0.0178
Echinococcus multilocularis expressed protein 0.0075 0.0095 0.0094
Schistosoma mansoni serine/threonine protein kinase 0.0059 0.0051 0.0073
Loa Loa (eye worm) hypothetical protein 0.0282 0.0659 0.0658
Trypanosoma cruzi casein kinase, putative 0.01 0.0163 0.2639
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0065 0.0067 0.0066
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.2145 0.5761 0.5761
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.011 0.019 0.0188
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.01 0.0163 0.0162
Trypanosoma brucei aurora B kinase 0.0081 0.0111 0.1652
Loa Loa (eye worm) hypothetical protein 0.011 0.019 0.0188
Loa Loa (eye worm) thyroid receptor interactor 0.0071 0.0082 0.0081
Echinococcus multilocularis serine:threonine protein kinase 38 0.0145 0.0285 0.0284
Loa Loa (eye worm) hypothetical protein 0.2145 0.5761 0.5761
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.013 0.0245 0.3787
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.011 0.0191 0.3101
Echinococcus multilocularis C2 calcium dependent membrane targeting 0.0042 0.0004 0.0003
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0065 0.0067 0.1073
Schistosoma mansoni hypothetical protein 0.0041 0.0001 0.0002
Trypanosoma brucei protein kinase, putative 0.0076 0.0096 0.1417
Schistosoma mansoni protein kinase 0.0421 0.104 0.1491
Entamoeba histolytica casein kinase, putative 0.01 0.0163 0.0542
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.015 0.0299 0.4938
Loa Loa (eye worm) hypothetical protein 0.008 0.0108 0.0107
Brugia malayi Protein kinase domain containing protein 0.0145 0.0285 0.0284
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.0047 0.0018 0.0017
Schistosoma mansoni serine/threonine protein kinase 0.0145 0.0285 0.0409
Loa Loa (eye worm) hypothetical protein 0.158 0.4214 0.4213
Echinococcus granulosus serine:threonine protein kinase TAO1 0.0212 0.0469 0.0469
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.011 0.019 0.0272
Loa Loa (eye worm) hypothetical protein 0.1009 0.2651 0.265
Echinococcus granulosus mitogen activated protein kinase 14 0.015 0.0299 0.0299
Onchocerca volvulus Tyrosine kinase homolog 0.0328 0.0786 0.0782
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.2145 0.5761 0.5761
Trichomonas vaginalis AGC family protein kinase 0.0081 0.0111 0.1652
Loa Loa (eye worm) hypothetical protein 0.0088 0.0129 0.0128
Loa Loa (eye worm) GABA receptor subunit 0.1136 0.2999 0.2998
Onchocerca volvulus 0.0314 0.0747 0.0743
Schistosoma mansoni unc-13 (munc13) 0.0042 0.0004 0.0006
Schistosoma mansoni protein kinase 0.0081 0.0111 0.0159
Brugia malayi Protein kinase domain containing protein 0.0921 0.2409 0.2408
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0136 0.0261 0.026
Echinococcus multilocularis casein kinase ii subunit alpha 0.0092 0.014 0.0139
Echinococcus multilocularis serine:threonine protein kinase 3 0.0246 0.0563 0.0562
Schistosoma mansoni neurotransmitter gated ion channel 0.1009 0.2651 0.38
Toxoplasma gondii cell-cycle-associated protein kinase SRPK, putative 0.0075 0.0095 0.1514
Brugia malayi Serine/threonine-protein kinase SULU 0.0212 0.0469 0.0468
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0228 0.0512 0.0512
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.013 0.0245 0.3952
Trichomonas vaginalis CAMK family protein kinase 0.0059 0.0051 0.0691
Echinococcus granulosus dual specificity 0.013 0.0245 0.0245
Giardia lamblia Kinase, CMGC GSK 0.012 0.0217 0.355
Entamoeba histolytica protein kinase, putative 0.0074 0.009 0.0297
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0093 0.0142 0.4733
Loa Loa (eye worm) hypothetical protein 0.0454 0.1132 0.1131
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0154 0.0309 0.5106
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0076 0.0096 0.1504
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0145 0.0285 0.4688
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0059 0.0051 0.0734
Schistosoma mansoni nAChR subunit 0.1009 0.2651 0.38
Brugia malayi hypothetical protein 0.1009 0.2651 0.265
Trichomonas vaginalis CAMK family protein kinase 0.0059 0.0051 0.0691
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.013 0.0245 0.402
Echinococcus granulosus glycogen synthase kinase 3 beta 0.012 0.0217 0.0217
Echinococcus multilocularis rho associated protein kinase 0.0314 0.0747 0.0746
Trichomonas vaginalis CMGC family protein kinase 0.012 0.0217 0.3345
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.2145 0.5761 0.5761
Entamoeba histolytica protein kinase, putative 0.013 0.0245 0.0814
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0148 0.0293 0.0293
Schistosoma mansoni tyrosine kinase 0.0107 0.0183 0.0262
Trichomonas vaginalis AGC family protein kinase 0.0273 0.0635 1
Brugia malayi excitatory GABA receptor EXP-1A 0.2145 0.5761 0.5761
Echinococcus multilocularis myotubularin protein 13 0.0047 0.0018 0.0017
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0077 0.0099 0.1546
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0078 0.0102 0.0101
Loa Loa (eye worm) ACC-1 protein 0.2145 0.5761 0.5761
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0073 0.0089 0.1423
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0065 0.0067 0.2103
Entamoeba histolytica protein kinase 2, putative 0.0148 0.0293 0.0973
Entamoeba histolytica serine/threonine protein kinase, putative 0.0043 0.0007 0.0021
Giardia lamblia Kinase, STE STE20 0.0078 0.0102 0.1608
Giardia lamblia Kinase, PLK 0.026 0.0599 1
Schistosoma mansoni protein kinase 0.0057 0.0044 0.0063
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.0059 0.0051 0.0734
Echinococcus multilocularis 0.0144 0.0283 0.0282
Trypanosoma cruzi cdc2-related kinase 3 0.011 0.0191 0.3101
Onchocerca volvulus 0.0075 0.0092 0.0088
Schistosoma mansoni serine/threonine protein kinase 0.0225 0.0504 0.0722
Brugia malayi Temporarily assigned gene name protein 59 0.0127 0.0236 0.0235
Schistosoma mansoni ste20-related kinase 0.0195 0.0423 0.0607
Echinococcus multilocularis serine threonine protein kinase 0.0185 0.0396 0.0395
Brugia malayi Kinase associated domain 1 family protein 0.006 0.0053 0.0052
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.2145 0.5761 0.8259
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0189 0.0406 0.0405
Trichomonas vaginalis STE family protein kinase 0.0078 0.0102 0.1514
Trichomonas vaginalis AGC family protein kinase 0.0273 0.0635 1
Echinococcus multilocularis protein kinase shaggy 0.012 0.0217 0.0216
Echinococcus granulosus nervana 2 0.0122 0.0222 0.0221
Brugia malayi Protein kinase domain containing protein 0.0191 0.0412 0.0411
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0074 0.009 0.0089
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0145 0.0285 0.0284
Echinococcus multilocularis PAK box P21 Rho binding 0.0057 0.0044 0.0043
Brugia malayi casein kinase 1, delta 0.01 0.0163 0.0162
Trypanosoma cruzi casein kinase, putative 0.01 0.0163 0.2639
Trichomonas vaginalis CAMK family protein kinase 0.0059 0.0051 0.0691
Trypanosoma brucei cdc2-related kinase 3 0.011 0.0191 0.2921
Trichomonas vaginalis CAMK family protein kinase 0.0059 0.0051 0.0691
Echinococcus granulosus mitogen activated protein kinase 3 0.0076 0.0096 0.0096
Trypanosoma cruzi p21-activated kinase 3, putative 0.0047 0.0018 0.0179
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.0328 0.0786 0.0785
Echinococcus multilocularis casein kinase I gamma 0.0203 0.0445 0.0444
Trichomonas vaginalis STE family protein kinase 0.0078 0.0102 0.1514
Echinococcus granulosus dual specificity 0.013 0.0245 0.0245
Loa Loa (eye worm) hypothetical protein 0.0071 0.0082 0.0081
Entamoeba histolytica PH domain containing protein kinase, putative 0.0154 0.0309 0.1029
Loa Loa (eye worm) hypothetical protein 0.2145 0.5761 0.5761
Loa Loa (eye worm) AUR protein kinase 0.0081 0.0111 0.011
Loa Loa (eye worm) hypothetical protein 0.1009 0.2651 0.265
Echinococcus multilocularis serine:threonine protein kinase 0.0106 0.0178 0.0177
Trypanosoma cruzi polo-like protein kinase, putative 0.026 0.0599 1
Trichomonas vaginalis AGC family protein kinase 0.0128 0.0238 0.3665
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0046 0.0015 0.0014
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.012 0.0217 0.355
Schistosoma mansoni protein kinase 0.0092 0.014 0.0201
Entamoeba histolytica protein kinase domain containing protein 0.012 0.0217 0.0722
Entamoeba histolytica serine/threonine protein kinase STE20, putative 0.0077 0.0099 0.0326
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0267 0.0619 0.0618
Plasmodium falciparum serine/threonine protein kinase KIN 0.0059 0.0051 0.1521
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0081 0.0111 0.0367
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.011 0.019 0.3079
Brugia malayi Protein kinase domain containing protein 0.0355 0.0859 0.0858
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0074 0.009 0.0089
Trichomonas vaginalis AGC family protein kinase 0.0273 0.0635 1
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.1009 0.2651 0.265
Echinococcus granulosus mitogen activated protein kinase 11 0.015 0.0299 0.0299
Trichomonas vaginalis AGC family protein kinase 0.0273 0.0635 1
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.1009 0.2651 0.265
Trichomonas vaginalis AGC family protein kinase 0.0081 0.0111 0.1652
Echinococcus multilocularis raf serine:threonine protein kinase 0.0051 0.0028 0.0027
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0148 0.0293 0.4824
Onchocerca volvulus 0.2589 0.6976 0.6975
Echinococcus granulosus MAP kinase activated protein kinase 2 0.0382 0.0933 0.0933
Schistosoma mansoni acetylcholine receptor-related 0.1009 0.2651 0.38
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0081 0.0111 0.0367
Trichomonas vaginalis mitogen-activated protein kinase kinase kinase 3, MAPKKK3, MEKK3, putative 0.0047 0.0018 0.0169
Brugia malayi Hr1 repeat family protein 0.0273 0.0635 0.0634
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.1009 0.2651 0.265
Echinococcus granulosus protein kinase 0.0144 0.0283 0.0283
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0093 0.0142 0.0141
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.01 0.0163 0.0162
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.1136 0.2999 0.4299
Echinococcus multilocularis casein kinase I delta 0.01 0.0163 0.0162
Trichomonas vaginalis STE family protein kinase 0.0057 0.0044 0.0584
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0059 0.0051 0.005
Brugia malayi C1-like domain containing protein 0.0208 0.0457 0.0456
Loa Loa (eye worm) hypothetical protein 0.2145 0.5761 0.5761
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.0222 0.0496 0.0495
Leishmania major casein kinase, putative 0.01 0.0163 0.2639
Schistosoma mansoni serine/threonine kinase 0.0145 0.0285 0.0409
Echinococcus multilocularis casein kinase I alpha 0.01 0.0163 0.0162
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.2145 0.5761 0.5761
Brugia malayi Protein kinase domain containing protein 0.0183 0.039 0.0389
Trichomonas vaginalis CMGC family protein kinase 0.013 0.0245 0.3787
Giardia lamblia Kinase, AGC AKT 0.0109 0.0186 0.3022
Schistosoma mansoni vav2 0.0052 0.0031 0.0045
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0128 0.0238 0.3829
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.2145 0.5761 0.5761
Schistosoma mansoni serine/threonine protein kinase 0.0065 0.0067 0.0097
Trichomonas vaginalis AGC family protein kinase 0.0081 0.0111 0.1652
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.2145 0.5761 0.5761
Schistosoma mansoni serine/threonine protein kinase 0.0065 0.0067 0.0097
Entamoeba histolytica serine/threonine protein kinase, putative 0.026 0.0599 0.1994
Onchocerca volvulus 0.1009 0.2651 0.2647
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0081 0.0111 0.0367
Schistosoma mansoni serine/threonine protein kinase 0.0086 0.0124 0.0178
Echinococcus multilocularis mitogen activated protein kinase 11 0.015 0.0299 0.0298
Plasmodium vivax casein kinase 1, putative 0.01 0.0163 0.5471
Loa Loa (eye worm) hypothetical protein 0.1136 0.2999 0.2998
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0065 0.0067 0.0956
Entamoeba histolytica protein kinase, putative 0.0075 0.0095 0.0312
Trypanosoma cruzi cdc2-related kinase 1 0.011 0.0191 0.3101
Schistosoma mansoni serine/threonine protein kinase 0.0245 0.0558 0.08
Giardia lamblia Kinase, CMGC SRPK 0.0075 0.0095 0.1475
Schistosoma mansoni tyrosine kinase 0.0058 0.0047 0.0067
Schistosoma mansoni hypothetical protein 0.006 0.0053 0.0076
Giardia lamblia Kinase, STE STE20 0.0077 0.0099 0.1546
Entamoeba histolytica hypothetical protein 0.0114 0.02 0.0664
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0114 0.02 0.3258
Trichomonas vaginalis AGC family protein kinase 0.0081 0.0111 0.1652
Brugia malayi Protein kinase domain containing protein 0.0145 0.0285 0.0284
Trichomonas vaginalis CMGC family protein kinase 0.011 0.0191 0.2921
Brugia malayi Pleckstrin Homology Domain 0.0047 0.0018 0.0017
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.2145 0.5761 0.5761
Brugia malayi protein kinase C II. 0.0187 0.0402 0.0401
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0059 0.0051 0.005
Loa Loa (eye worm) hypothetical protein 0.2145 0.5761 0.5761
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0076 0.0096 0.1504
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0328 0.0786 0.0785
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.1009 0.2651 0.265
Onchocerca volvulus 0.1009 0.2651 0.2647
Loa Loa (eye worm) hypothetical protein 0.1009 0.2651 0.265
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.1136 0.2999 0.4299
Onchocerca volvulus 0.0137 0.0262 0.0258
Loa Loa (eye worm) hypothetical protein 0.2145 0.5761 0.5761
Loa Loa (eye worm) hypothetical protein 0.006 0.0053 0.0052
Echinococcus multilocularis insulin receptor 0.0138 0.0267 0.0266
Echinococcus granulosus dual specificity protein kinase clk2 0.0145 0.0285 0.0285
Trichomonas vaginalis CMGC family protein kinase 0.013 0.0245 0.3787
Trichomonas vaginalis CMGC family protein kinase 0.013 0.0245 0.3787
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0208 0.0457 0.0456
Schistosoma mansoni hypothetical protein 0.006 0.0053 0.0076
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0075 0.0092 0.1437
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.012 0.0217 0.0216
Giardia lamblia Kinase, CMGC MAPK 0.0076 0.0096 0.1504
Echinococcus multilocularis dual specificity 0.013 0.0245 0.0244
Loa Loa (eye worm) hypothetical protein 0.0137 0.0262 0.0261
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0114 0.02 0.0199
Trichomonas vaginalis CMGC family protein kinase 0.0145 0.0285 0.4416
Loa Loa (eye worm) hypothetical protein 0.2145 0.5761 0.5761
Schistosoma mansoni tyrosine kinase 0.0058 0.0047 0.0067
Leishmania major protein kinase A catalytic subunit isoform 2 0.0065 0.0067 0.1015
Loa Loa (eye worm) AUR protein kinase 0.0081 0.0111 0.011
Schistosoma mansoni protein kinase 0.0078 0.0102 0.0147
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.015 0.0299 0.4938
Brugia malayi Immunoglobulin I-set domain containing protein 0.0345 0.0832 0.0831
Entamoeba histolytica serine/threonine-protein kinase 3, putative 0.0077 0.0099 0.0326
Loa Loa (eye worm) hypothetical protein 0.1009 0.2651 0.265
Trichomonas vaginalis AGC family protein kinase 0.0074 0.009 0.132
Loa Loa (eye worm) hypothetical protein 0.2589 0.6976 0.6976
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.013 0.0245 0.402
Echinococcus granulosus protein kinase c eta type 0.0041 0.0001 0.0001
Schistosoma mansoni protein kinase 0.0189 0.0406 0.0581
Trichomonas vaginalis AGC family protein kinase 0.0074 0.009 0.132
Trypanosoma brucei rac serine-threonine kinase, putative 0.0273 0.0635 1
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.2145 0.5761 0.8259
Trichomonas vaginalis AGC family protein kinase 0.0273 0.0635 1
Giardia lamblia Kinase, CK1 Casein kinase 0.01 0.0163 0.2639
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.011 0.0191 0.3072
Schistosoma mansoni serine/threonine protein kinase 0.0081 0.0111 0.0159

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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