Detailed information for compound 1578650

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 366.412 | Formula: C24H18N2O2
  • H donors: 1 H acceptors: 2 LogP: 4.65 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: N#CC1=C(N)Oc2c(C1c1cccc(c1)/C=C/C(=O)C)c1ccccc1cc2
  • InChi: 1S/C24H18N2O2/c1-15(27)9-10-16-5-4-7-18(13-16)22-20(14-25)24(26)28-21-12-11-17-6-2-3-8-19(17)23(21)22/h2-13,22H,26H2,1H3/b10-9+
  • InChiKey: UQFIDJVNIUMYPV-MDZDMXLPSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis tubulin beta chain, putative 0.0386 0.4256 0.7296
Echinococcus granulosus tyrosine kinase 0.0068 0.0617 0.0579
Echinococcus multilocularis tubulin alpha 3 chain 0.0386 0.4256 0.4233
Echinococcus multilocularis Tubulin beta 2C chain 0.0523 0.5819 0.5802
Leishmania major beta tubulin 0.0523 0.5819 1
Mycobacterium tuberculosis Probable reductase 0.0114 0.115 0.2297
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.005 0.0415 0.0776
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0045 0.0358 0.0551
Schistosoma mansoni metabotropic glutamate receptor 2 3 (mglur group 2) 0.0821 0.9224 1
Loa Loa (eye worm) hypothetical protein 0.0017 0.0031 0.0029
Loa Loa (eye worm) hypothetical protein 0.016 0.1674 0.1672
Loa Loa (eye worm) tubulin beta chain 0.0121 0.1228 0.1226
Echinococcus granulosus alpha tubulin 0.0386 0.4256 0.4233
Entamoeba histolytica tubulin gamma chain 0.028 0.3036 0.4977
Brugia malayi hypothetical protein 0.0038 0.0278 0.034
Mycobacterium tuberculosis Conserved protein 0.0069 0.0628 0.1218
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0068 0.0617 0.3101
Leishmania major alpha tubulin 0.0386 0.4256 0.7296
Echinococcus multilocularis GPCR, family 3, C terminal 0.0117 0.118 0.1145
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0018 0.0052 0.0026
Loa Loa (eye worm) cytochrome P450 family protein 0.0036 0.0256 0.0254
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0018 0.0052 0.0026
Loa Loa (eye worm) alpha-tubulin 0.0386 0.4256 0.4255
Loa Loa (eye worm) alpha-tubulin 0.0386 0.4256 0.4255
Leishmania major alpha tubulin 0.0386 0.4256 0.7296
Schistosoma mansoni tubulin subunit gamma 0.028 0.3036 0.327
Trichomonas vaginalis DNA helicase recq1, putative 0.0021 0.0079 0.0068
Brugia malayi alpha-tubulin 0.0386 0.4256 0.5258
Mycobacterium ulcerans cell division protein FtsZ 0.0121 0.1228 1
Echinococcus granulosus beta LACTamase domain containing family member 0.0069 0.0628 0.0591
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0018 0.005 0.0018
Echinococcus multilocularis 0.0018 0.0052 0.0012
Brugia malayi beta-tubulin, identical 0.0523 0.5819 0.7189
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0018 0.0052 0.0026
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0069 0.0628 0.1218
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0018 0.0052 0.0026
Schistosoma mansoni hypothetical protein 0.0023 0.0099 0.0077
Echinococcus multilocularis thioredoxin glutathione reductase 0.005 0.0415 0.0376
Schistosoma mansoni hypothetical protein 0.0038 0.0278 0.027
Loa Loa (eye worm) hypothetical protein 0.0069 0.0628 0.0626
Plasmodium vivax tubulin alpha chain, putative 0.0386 0.4256 0.7313
Loa Loa (eye worm) hypothetical protein 0.0068 0.0617 0.0615
Loa Loa (eye worm) cytochrome P450 family protein 0.0036 0.0256 0.0254
Loa Loa (eye worm) hypothetical protein 0.0069 0.0628 0.0626
Echinococcus multilocularis tubulin delta chain 0.0121 0.1228 0.1193
Loa Loa (eye worm) hypothetical protein 0.0062 0.0553 0.0551
Mycobacterium leprae Probable lipase LipE 0.0069 0.0628 0.4634
Echinococcus granulosus histone acetyltransferase KAT2B 0.015 0.155 0.1516
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0018 0.0052 0.0026
Echinococcus granulosus bloom syndrome protein 0.0021 0.0079 0.0039
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0068 0.0617 0.0579
Mycobacterium tuberculosis Probable esterase LipL 0.0069 0.0628 0.1218
Echinococcus multilocularis beta LACTamase domain containing family member 0.0069 0.0628 0.0591
Brugia malayi metabotropic glutamate receptor type 2 0.0352 0.3863 0.4772
Trichomonas vaginalis tubulin, putative 0.0158 0.1649 0.2784
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0023 0.0099 0.006
Schistosoma mansoni cytochrome P450 0.0018 0.0052 0.0025
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0069 0.0628 0.0652
Trichomonas vaginalis tubulin beta-1 chain, putative 0.0121 0.1228 0.2056
Leishmania major gamma-tubulin 0.028 0.3036 0.5184
Plasmodium falciparum tubulin gamma chain 0.028 0.3036 0.5184
Trypanosoma brucei alpha tubulin 0.0386 0.4256 0.7296
Loa Loa (eye worm) hypothetical protein 0.0069 0.0628 0.0626
Loa Loa (eye worm) tubulin beta-4 chain 0.0523 0.5819 0.5818
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0017 0.004 0.0012
Loa Loa (eye worm) hypothetical protein 0.0069 0.0628 0.0626
Trypanosoma brucei PAB1-binding protein , putative 0.005 0.0417 0.0653
Leishmania major alpha tubulin 0.0386 0.4256 0.7296
Brugia malayi beta-lactamase family protein 0.0069 0.0628 0.0774
Trypanosoma brucei hypothetical protein, conserved 0.0069 0.0628 0.1018
Leishmania major hypothetical protein, conserved 0.005 0.0417 0.0653
Brugia malayi Cytochrome P450 family protein 0.0018 0.0052 0.0062
Leishmania major beta tubulin 0.0523 0.5819 1
Entamoeba histolytica acetyltransferase, GNAT family 0.0041 0.0315 0.0068
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0018 0.0052 0.0026
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0018 0.0052 0.0104
Loa Loa (eye worm) CYP4Cod1 0.0036 0.0256 0.0254
Schistosoma mansoni calcium-activated potassium channel 0.0124 0.1262 0.1341
Onchocerca volvulus 0.0068 0.0617 0.3101
Toxoplasma gondii thioredoxin reductase 0.005 0.0415 0.0713
Trichomonas vaginalis tubulin gamma chain, putative 0.028 0.3036 0.5184
Trichomonas vaginalis conserved hypothetical protein 0.0121 0.1228 0.2056
Onchocerca volvulus 0.0069 0.0628 0.3176
Trichomonas vaginalis tubulin gamma chain, putative 0.0121 0.1228 0.2056
Brugia malayi Intermediate filament tail domain containing protein 0.0026 0.0142 0.0173
Giardia lamblia Epsilon tubulin 0.0121 0.1228 0.2056
Brugia malayi Tubulin alpha chain 0.0121 0.1228 0.1515
Echinococcus multilocularis tubulin subunit beta 0.0523 0.5819 0.5802
Onchocerca volvulus Poor gastrulation protein homolog 0.0117 0.118 0.6778
Loa Loa (eye worm) hypothetical protein 0.0056 0.048 0.0478
Echinococcus multilocularis tubulin alpha 1C chain 0.0386 0.4256 0.4233
Onchocerca volvulus 0.016 0.1674 1
Giardia lamblia Alpha-tubulin 0.0386 0.4256 0.7296
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0026 0.0142 0.014
Entamoeba histolytica tubulin alpha-1 chain 0.0386 0.4256 0.718
Trichomonas vaginalis penicillin-binding protein, putative 0.0069 0.0628 0.1018
Loa Loa (eye worm) intermediate filament protein 0.0026 0.0142 0.014
Brugia malayi hypothetical protein 0.0033 0.0213 0.0261
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0047 0.0379 0.0466
Trypanosoma brucei tubulin gamma chain 0.028 0.3036 0.5184
Schistosoma mansoni tubulin subunit delta 0.0121 0.1228 0.1304
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0018 0.0052 0.0026
Plasmodium vivax ataxin-2 like protein, putative 0.005 0.0417 0.0714
Schistosoma mansoni tyrosine kinase 0.0068 0.0617 0.064
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0018 0.0052 0.0104
Trypanosoma cruzi epsilon tubulin, putative 0.028 0.3036 0.5184
Echinococcus multilocularis Tubulin alpha 1 chain 0.0386 0.4256 0.4233
Schistosoma mansoni hypothetical protein 0.0018 0.0052 0.0025
Leishmania major alpha tubulin 0.0386 0.4256 0.7296
Echinococcus multilocularis tubulin alpha chain 0.0386 0.4256 0.4233
Plasmodium vivax hypothetical protein, conserved 0.0069 0.0628 0.1077
Trichomonas vaginalis tubulin epsilon chain, putative 0.0523 0.5819 1
Plasmodium vivax thioredoxin reductase, putative 0.005 0.0415 0.071
Echinococcus multilocularis glutamate receptor 2 0.0068 0.0617 0.0579
Mycobacterium ulcerans beta-lactamase 0.0069 0.0628 0.4953
Echinococcus multilocularis receptor type guanylyl cyclase 0.0068 0.0617 0.0579
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0386 0.4256 0.7296
Echinococcus granulosus receptor type guanylyl cyclase 0.0068 0.0617 0.0579
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0018 0.0052 0.0104
Echinococcus granulosus glutamate receptor 2 0.0068 0.0617 0.0579
Loa Loa (eye worm) hypothetical protein 0.0228 0.2449 0.2447
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0069 0.0628 0.1218
Leishmania major beta tubulin 0.0523 0.5819 1
Trypanosoma cruzi hypothetical protein, conserved 0.0069 0.0628 0.1018
Echinococcus multilocularis Tubulin beta 2C chain 0.0523 0.5819 0.5802
Plasmodium vivax tubulin alpha chain, putative 0.0386 0.4256 0.7313
Schistosoma mansoni transcription factor LCR-F1 0.0038 0.0278 0.027
Echinococcus multilocularis metabotropic glutamate receptor 2 0.0605 0.6754 0.6741
Trichomonas vaginalis tubulin epsilon chain, putative 0.0386 0.4256 0.7296
Mycobacterium tuberculosis Probable oxidoreductase 0.0127 0.1296 0.2599
Echinococcus granulosus tubulin alpha chain 0.0386 0.4256 0.4233
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0121 0.1228 0.2111
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0127 0.1296 0.2599
Echinococcus multilocularis Tubulin alpha 1 chain 0.0386 0.4256 0.4233
Loa Loa (eye worm) hypothetical protein 0.0068 0.0617 0.0615
Leishmania major cytochrome p450-like protein 0.0018 0.0052 0.0021
Echinococcus granulosus tubulin alpha chain 0.0386 0.4256 0.4233
Mycobacterium tuberculosis Cell division protein FtsZ 0.0121 0.1228 0.246
Leishmania major hypothetical protein, conserved 0.0069 0.0628 0.1018
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0018 0.0052 0.0021
Toxoplasma gondii ABC1 family protein 0.0069 0.0628 0.108
Loa Loa (eye worm) hypothetical protein 0.0889 1 1
Loa Loa (eye worm) hypothetical protein 0.0117 0.118 0.1179
Loa Loa (eye worm) receptor family ligand binding region containing protein 0.0185 0.1956 0.1955
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0889 1 1
Schistosoma mansoni metabotropic glutamate receptor 0.0352 0.3863 0.417
Plasmodium falciparum ataxin-2 like protein, putative 0.005 0.0417 0.0653
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0154 0.1599 0.1566
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0018 0.0052 0.0026
Loa Loa (eye worm) hypothetical protein 0.0069 0.0628 0.0626
Echinococcus granulosus tubulin beta 4A class IVa 0.0523 0.5819 0.5802
Echinococcus multilocularis geminin 0.0165 0.173 0.1697
Leishmania major beta tubulin 0.0523 0.5819 1
Brugia malayi tubulin alpha chain - mouse 0.0386 0.4256 0.5258
Echinococcus granulosus Tubulin alpha 1 chain 0.0386 0.4256 0.4233
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0018 0.0052 0.0026
Echinococcus granulosus tubulin alpha 0.028 0.3036 0.3008
Schistosoma mansoni tubulin subunit beta 0.0121 0.1228 0.1304
Toxoplasma gondii beta tubulin 0.0523 0.5819 1
Echinococcus multilocularis tubulin alpha chain 0.0386 0.4256 0.4233
Echinococcus granulosus tubulin beta 1 chain 0.0523 0.5819 0.5802
Echinococcus multilocularis Tubulin beta 2C chain 0.0523 0.5819 0.5802
Entamoeba histolytica tubulin family protein 0.0523 0.5819 1
Trichomonas vaginalis tubulin beta chain, putative 0.0386 0.4256 0.7296
Leishmania major extracellular receptor, putative 0.0068 0.0617 0.0999
Echinococcus granulosus tubulin alpha 3 chain 0.0386 0.4256 0.4233
Echinococcus multilocularis lamin dm0 0.0026 0.0142 0.0102
Mycobacterium tuberculosis Conserved protein 0.0069 0.0628 0.1218
Mycobacterium tuberculosis Probable dehydrogenase 0.0114 0.115 0.2297
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0018 0.0052 0.0026
Echinococcus granulosus Tubulin beta 2C chain 0.0523 0.5819 0.5802
Trypanosoma cruzi tubulin delta chain 0.0121 0.1228 0.2056
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0228 0.2449 0.4168
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0017 0.004 0.0068
Echinococcus multilocularis tyrosine kinase 0.0068 0.0617 0.0579
Mycobacterium leprae cell division protein FtsZ 0.0121 0.1228 0.9458
Loa Loa (eye worm) metabotropic GABA-B receptor subtype 2 0.0185 0.1956 0.1955
Trypanosoma cruzi trypanothione reductase, putative 0.005 0.0415 0.0649
Schistosoma mansoni alpha tubulin 0.0386 0.4256 0.4597
Echinococcus granulosus Tubulin alpha 1 chain 0.0386 0.4256 0.4233
Trichomonas vaginalis tubulin, putative 0.0121 0.1228 0.2056
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0068 0.0617 0.0579
Trichomonas vaginalis tubulin beta chain, putative 0.0386 0.4256 0.7296
Plasmodium falciparum histone acetyltransferase GCN5 0.0041 0.0315 0.0476
Echinococcus granulosus cytochrome P450 2K1 0.0018 0.0052 0.0012
Loa Loa (eye worm) RecQ helicase 0.0021 0.0079 0.0077
Leishmania major beta tubulin 0.0523 0.5819 1
Leishmania major beta tubulin 0.0523 0.5819 1
Brugia malayi Tubulin alpha chain 0.0386 0.4256 0.5258
Echinococcus multilocularis peroxisome assembly protein 26 0.0386 0.4256 0.4233
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0121 0.1228 0.2111
Schistosoma mansoni hypothetical protein 0.0165 0.173 0.185
Schistosoma mansoni hypothetical protein 0.0165 0.173 0.185
Trichomonas vaginalis tubulin alpha chain, putative 0.028 0.3036 0.5184
Brugia malayi hypothetical protein 0.016 0.1674 0.2067
Leishmania major alpha tubulin 0.0386 0.4256 0.7296
Brugia malayi Tubulin gamma chain 0.028 0.3036 0.3749
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0069 0.0628 0.0774
Mycobacterium tuberculosis Probable lipase LipD 0.0069 0.0628 0.1218
Trichomonas vaginalis tubulin alpha chain, putative 0.0158 0.1649 0.2784
Trypanosoma brucei alpha tubulin 0.0386 0.4256 0.7296
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0069 0.0628 0.4953
Trichomonas vaginalis D-aminoacylase, putative 0.0069 0.0628 0.1018
Echinococcus granulosus microtubule associated protein 2 0.0673 0.7534 0.7524
Plasmodium falciparum ataxin-2 like protein, putative 0.005 0.0417 0.0653
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0018 0.0052 0.0021
Brugia malayi Tubulin beta chain 0.0158 0.1649 0.2035
Echinococcus multilocularis microtubule associated protein 2 0.0673 0.7534 0.7524
Schistosoma mansoni tubulin subunit alpha 0.0386 0.4256 0.4597
Loa Loa (eye worm) hypothetical protein 0.0386 0.4256 0.4255
Loa Loa (eye worm) tubulin beta chain 0.0523 0.5819 0.5818
Brugia malayi Guanylyl cyclase protein 23 0.0068 0.0617 0.076
Echinococcus granulosus tubulin alpha 1C chain 0.0386 0.4256 0.4233
Schistosoma mansoni hypothetical protein 0.0117 0.118 0.1252
Mycobacterium leprae conserved hypothetical protein 0.0069 0.0628 0.4634
Echinococcus multilocularis glutamate receptor 2 0.0068 0.0617 0.0579
Schistosoma mansoni microtubule-associated protein tau 0.0673 0.7534 0.8162
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0117 0.118 0.1456
Schistosoma mansoni glutamate receptor NMDA 0.0068 0.0617 0.064
Leishmania major beta tubulin 0.0523 0.5819 1
Mycobacterium ulcerans esterase/lipase LipP 0.0069 0.0628 0.4953
Mycobacterium ulcerans lipase LipD 0.0069 0.0628 0.4953
Giardia lamblia Histone acetyltransferase GCN5 0.0041 0.0315 0.0476
Plasmodium falciparum alpha tubulin 2 0.0386 0.4256 0.7296
Leishmania major beta tubulin 0.0523 0.5819 1
Toxoplasma gondii LsmAD domain-containing protein 0.005 0.0417 0.0717
Trypanosoma cruzi cytochrome P450, putative 0.0036 0.0256 0.0374
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0068 0.0617 0.0579
Loa Loa (eye worm) beta-tubulin 0.0523 0.5819 0.5818
Trypanosoma cruzi extracellular receptor, putative 0.0068 0.0617 0.0999
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0127 0.1296 0.2599
Loa Loa (eye worm) RGC/RGC protein kinase 0.0068 0.0617 0.0615
Trichomonas vaginalis tubulin beta chain, putative 0.0158 0.1649 0.2784
Giardia lamblia Delta tubulin 0.0121 0.1228 0.2056
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0018 0.0052 0.0026
Entamoeba histolytica tubulin family protein 0.0523 0.5819 1
Loa Loa (eye worm) RGC/RGC protein kinase 0.0068 0.0617 0.0615
Echinococcus multilocularis survival motor neuron protein 1 0.0231 0.2477 0.2447
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0045 0.0358 0.0615
Onchocerca volvulus Metabotropic glutamate receptor homolog 0.0117 0.118 0.6778
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0018 0.0052 0.0104
Echinococcus multilocularis tubulin alpha 3 chain 0.0386 0.4256 0.4233
Leishmania major delta tubulin, putative 0.0121 0.1228 0.2056
Trichomonas vaginalis tubulin alpha chain, putative 0.0158 0.1649 0.2784
Echinococcus multilocularis tubulin alpha 0.028 0.3036 0.3008
Brugia malayi Tubulin alpha-2 chain 0.0386 0.4256 0.5258
Brugia malayi Receptor family ligand binding region containing protein 0.0068 0.0617 0.076
Leishmania major beta tubulin 0.0523 0.5819 1
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0017 0.004 0.0047
Brugia malayi intermediate filament protein 0.0026 0.0142 0.0173
Trypanosoma brucei zeta tubulin, putative 0.0121 0.1228 0.2056
Trypanosoma brucei alpha tubulin 0.0386 0.4256 0.7296
Leishmania major epsilon tubulin, putative 0.028 0.3036 0.5184
Treponema pallidum cell division protein FtsZ 0.0121 0.1228 1
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0023 0.0099 0.006
Trichomonas vaginalis tubulin, putative 0.0158 0.1649 0.2784
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0069 0.0628 0.1218
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0018 0.0052 0.0104
Wolbachia endosymbiont of Brugia malayi cell division protein FtsZ 0.0121 0.1228 1
Loa Loa (eye worm) tubulin beta-1 chain 0.0523 0.5819 0.5818
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0018 0.0052 0.0026
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0017 0.004 0.0065
Leishmania major alpha tubulin 0.0386 0.4256 0.7296
Schistosoma mansoni calcium-activated potassium channel 0.0118 0.1192 0.1265
Schistosoma mansoni hypothetical protein 0.0124 0.1262 0.1341
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0018 0.0052 0.0026
Schistosoma mansoni tubulin subunit alpha 0.0386 0.4256 0.4597
Leishmania major beta tubulin 0.0523 0.5819 1
Trichomonas vaginalis D-aminoacylase, putative 0.0069 0.0628 0.1018
Brugia malayi Cytochrome P450 family protein 0.0036 0.0256 0.0314
Echinococcus multilocularis beta tubulin 0.0523 0.5819 0.5802
Plasmodium vivax delta tubulin, putative 0.0121 0.1228 0.2108
Schistosoma mansoni tubulin subunit epsilon 0.028 0.3036 0.327
Schistosoma mansoni alpha tubulin 0.0386 0.4256 0.4597
Onchocerca volvulus 0.0069 0.0628 0.3176
Brugia malayi cytochrome P450 0.0018 0.0052 0.0062
Loa Loa (eye worm) glutamate receptor 0.0722 0.8093 0.8093
Plasmodium falciparum glutathione reductase 0.005 0.0415 0.0649
Trypanosoma brucei zeta tubulin 0.0121 0.1228 0.2056
Entamoeba histolytica tubulin alpha chain, putative 0.0386 0.4256 0.718
Echinococcus granulosus tubulin subunit beta 0.0523 0.5819 0.5802
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0265 0.2869 0.4896
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0038 0.0278 0.0239
Loa Loa (eye worm) tubulin alpha-3 chain 0.0228 0.2449 0.2447
Echinococcus granulosus Tubulin alpha 1 chain 0.0386 0.4256 0.4233
Trichomonas vaginalis tubulin epsilon chain, putative 0.0523 0.5819 1
Trichomonas vaginalis tubulin epsilon chain, putative 0.0121 0.1228 0.2056
Toxoplasma gondii beta-tubulin, putative 0.0523 0.5819 1
Loa Loa (eye worm) beta-lactamase 0.0069 0.0628 0.0626
Loa Loa (eye worm) hypothetical protein 0.0026 0.0142 0.014
Trypanosoma cruzi alpha tubulin, putative 0.0386 0.4256 0.7296
Schistosoma mansoni survival motor neuron protein 0.0047 0.0379 0.038
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0018 0.0052 0.0104
Leishmania major alpha tubulin 0.0386 0.4256 0.7296
Echinococcus granulosus histone acetyltransferase KAT2B 0.0045 0.0358 0.032
Loa Loa (eye worm) BEN-1 protein 0.0523 0.5819 0.5818
Echinococcus granulosus tubulin delta chain 0.0121 0.1228 0.1193
Trypanosoma cruzi hypothetical protein, conserved 0.0069 0.0628 0.1018
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0018 0.0052 0.0026
Trichomonas vaginalis esterase, putative 0.0069 0.0628 0.1018
Mycobacterium tuberculosis Possible penicillin-binding protein 0.044 0.4871 1
Trypanosoma brucei epsilon tubulin 0.028 0.3036 0.5184
Brugia malayi Cytochrome P450 family protein 0.0036 0.0256 0.0314
Giardia lamblia Beta tubulin 0.0523 0.5819 1
Loa Loa (eye worm) metabotropic glutamate receptor 8 0.0068 0.0617 0.0615
Leishmania major alpha tubulin 0.0386 0.4256 0.7296
Echinococcus granulosus tubulin gamma 1 chain 0.028 0.3036 0.3008
Echinococcus granulosus peroxisome assembly protein 26 0.0386 0.4256 0.4233
Plasmodium falciparum thioredoxin reductase 0.005 0.0415 0.0649
Trichomonas vaginalis tubulin alpha chain, putative 0.0158 0.1649 0.2784
Leishmania major beta tubulin 0.0523 0.5819 1
Schistosoma mansoni protein kinase 0.0068 0.0617 0.064
Leishmania major beta tubulin 0.0523 0.5819 1
Echinococcus granulosus tubulin alpha 3 chain 0.0386 0.4256 0.4233
Loa Loa (eye worm) hypothetical protein 0.0026 0.0136 0.0134
Loa Loa (eye worm) tubulin gamma chain 0.028 0.3036 0.3034
Trypanosoma brucei cytochrome P450, putative 0.0036 0.0256 0.0374
Loa Loa (eye worm) thioredoxin reductase 0.005 0.0415 0.0413
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0114 0.115 0.2297
Echinococcus multilocularis Tubulin beta 2C chain 0.0523 0.5819 0.5802
Echinococcus multilocularis tubulin beta 1 chain 0.0523 0.5819 0.5802
Loa Loa (eye worm) tubulin beta-2A chain 0.0523 0.5819 0.5818
Onchocerca volvulus 0.0047 0.0379 0.1547
Toxoplasma gondii alpha tubulin TUBA1 0.0386 0.4256 0.7314
Loa Loa (eye worm) hypothetical protein 0.0068 0.0617 0.0615
Brugia malayi Bloom's syndrome protein homolog 0.0021 0.0079 0.0095
Echinococcus granulosus intermediate filament protein 0.0026 0.0142 0.0102
Loa Loa (eye worm) hypothetical protein 0.0124 0.1262 0.126
Echinococcus granulosus glutamate receptor 2 0.0068 0.0617 0.0579
Mycobacterium tuberculosis Conserved protein 0.0069 0.0628 0.1218
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0018 0.0052 0.0021
Brugia malayi Receptor family ligand binding region containing protein 0.0185 0.1956 0.2415
Echinococcus granulosus tubulin alpha chain 0.0386 0.4256 0.4233
Trypanosoma brucei epsilon tubulin 0.028 0.3036 0.5184
Schistosoma mansoni tubulin subunit beta 0.0523 0.5819 0.6297
Trichomonas vaginalis tubulin beta chain, putative 0.0386 0.4256 0.7296
Brugia malayi Cytochrome P450 family protein 0.0059 0.0515 0.0634
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0018 0.0052 0.0104
Brugia malayi beta-lactamase 0.0069 0.0628 0.0774
Brugia malayi Metabotropic glutamate receptor precursor. 0.0722 0.8093 1
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0068 0.0617 0.0579
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0068 0.0617 0.0579
Echinococcus granulosus small conductance calcium activated potassium 0.0124 0.1262 0.1227
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0018 0.0052 0.0104
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0018 0.0052 0.0104
Mycobacterium tuberculosis Probable hydrolase 0.0069 0.0628 0.1218
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0018 0.0052 0.0026
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0018 0.0052 0.0104
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.028 0.3036 0.5217
Brugia malayi Tubulin beta chain 0.0121 0.1228 0.1515
Schistosoma mansoni lamin 0.0026 0.0142 0.0123
Giardia lamblia Gamma tubulin 0.028 0.3036 0.5184
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0114 0.115 0.2297
Toxoplasma gondii NADPH-glutathione reductase 0.0017 0.004 0.0068
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0069 0.0628 0.0626
Echinococcus multilocularis beta tubulin 0.0523 0.5819 0.5802
Schistosoma mansoni alpha tubulin 0.0386 0.4256 0.4597
Loa Loa (eye worm) glutathione reductase 0.005 0.0415 0.0413
Trypanosoma cruzi PAB1-binding protein , putative 0.005 0.0417 0.0653
Echinococcus granulosus Tubulin beta 2C chain 0.0523 0.5819 0.5802
Trypanosoma cruzi epsilon tubulin, putative 0.028 0.3036 0.5184
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0114 0.115 0.2297
Echinococcus granulosus atrial natriuretic peptide receptor 0.0068 0.0617 0.0579
Echinococcus multilocularis Tubulin alpha 1 chain 0.0386 0.4256 0.4233
Trichomonas vaginalis tubulin gamma chain, putative 0.0523 0.5819 1
Echinococcus granulosus tubulin alpha 1C chain 0.0386 0.4256 0.4233
Loa Loa (eye worm) hypothetical protein 0.0069 0.0628 0.0626
Leishmania major beta tubulin 0.0523 0.5819 1
Echinococcus granulosus tubulin epsilon chain 0.028 0.3036 0.3008
Echinococcus granulosus thioredoxin glutathione reductase 0.005 0.0415 0.0376
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0018 0.0052 0.0026
Schistosoma mansoni hypothetical protein 0.0047 0.0379 0.038
Brugia malayi hypothetical protein 0.0068 0.0617 0.076
Plasmodium vivax tubulin epsilon chain, putative 0.028 0.3036 0.5215
Trichomonas vaginalis DNA helicase recq, putative 0.0021 0.0079 0.0068
Echinococcus granulosus tubulin subunit TubB 0.0386 0.4256 0.4233
Leishmania major zeta tubulin, putative 0.0121 0.1228 0.2056
Leishmania major trypanothione reductase 0.005 0.0415 0.0649
Loa Loa (eye worm) tubulin alpha 2 0.0265 0.2869 0.2868
Echinococcus granulosus Tubulin beta 2C chain 0.0523 0.5819 0.5802
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0068 0.0617 0.0579
Plasmodium falciparum alpha tubulin 1 0.0386 0.4256 0.7296
Leishmania major alpha tubulin 0.0386 0.4256 0.7296
Trichomonas vaginalis conserved hypothetical protein 0.0121 0.1228 0.2056
Loa Loa (eye worm) hypothetical protein 0.0068 0.0617 0.0615
Trichomonas vaginalis bromodomain-containing protein, putative 0.0045 0.0358 0.0551
Loa Loa (eye worm) hypothetical protein 0.0068 0.0617 0.0615
Loa Loa (eye worm) cytochrome P450 family protein 0.0059 0.0515 0.0513
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0114 0.115 0.2297
Loa Loa (eye worm) RGC/RGC protein kinase 0.0068 0.0617 0.0615
Leishmania major beta tubulin 0.0523 0.5819 1
Plasmodium vivax glutathione reductase, putative 0.005 0.0415 0.071
Echinococcus multilocularis nmda type glutamate receptor 0.0068 0.0617 0.0579
Leishmania major beta tubulin 0.0523 0.5819 1
Trypanosoma brucei tubulin delta chain 0.0121 0.1228 0.2056
Echinococcus multilocularis bloom syndrome protein 0.0021 0.0079 0.0039
Echinococcus granulosus nmda type glutamate receptor 0.0068 0.0617 0.0579
Echinococcus multilocularis tubulin alpha 1C chain 0.0386 0.4256 0.4233
Trichomonas vaginalis tubulin beta chain, putative 0.0386 0.4256 0.7296
Trypanosoma brucei alpha tubulin 0.0386 0.4256 0.7296
Trypanosoma cruzi zeta tubulin, putative 0.0121 0.1228 0.2056
Brugia malayi Thioredoxin reductase 0.005 0.0415 0.051
Leishmania major cytochrome p450-like protein 0.0036 0.0256 0.0374
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0018 0.0052 0.0026
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0068 0.0617 0.0579
Echinococcus granulosus beta tubulin 0.0523 0.5819 0.5802
Echinococcus granulosus Tubulin beta 2C chain 0.0523 0.5819 0.5802
Echinococcus multilocularis lamin 0.0026 0.0142 0.0102
Plasmodium falciparum tubulin epsilon chain, putative 0.028 0.3036 0.5184
Trypanosoma brucei beta tubulin 0.028 0.3036 0.5184
Trichomonas vaginalis penicillin-binding protein, putative 0.0069 0.0628 0.1018
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0068 0.0617 0.076
Giardia lamblia Beta tubulin 0.0523 0.5819 1
Brugia malayi glutathione reductase 0.005 0.0415 0.051
Schistosoma mansoni tubulin subunit beta 0.0523 0.5819 0.6297
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0018 0.0052 0.0104
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0018 0.0052 0.0021
Echinococcus multilocularis tubulin alpha chain 0.0386 0.4256 0.4233
Trypanosoma brucei epsilon tubulin 0.028 0.3036 0.5184
Trypanosoma cruzi PAB1-binding protein , putative 0.005 0.0417 0.0653
Echinococcus granulosus lamin dm0 0.0026 0.0142 0.0102
Plasmodium vivax tubulin gamma chain, putative 0.028 0.3036 0.5215
Brugia malayi Tubulin alpha-2 chain 0.0386 0.4256 0.5258
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0017 0.004 0.0065
Trypanosoma cruzi beta tubulin, putative 0.0523 0.5819 1
Schistosoma mansoni tubulin subunit beta 0.0523 0.5819 0.6297
Loa Loa (eye worm) alpha-tubulin isotype 2 0.0265 0.2869 0.2868
Brugia malayi Cell division protein ftsZ 0.0121 0.1228 0.1515
Trichomonas vaginalis tubulin alpha chain, putative 0.0523 0.5819 1
Brugia malayi hypothetical protein 0.005 0.0417 0.0513
Echinococcus multilocularis tubulin alpha chain 0.0386 0.4256 0.4233
Echinococcus granulosus GPCR family 3 C terminal 0.0117 0.118 0.1145
Echinococcus multilocularis atrial natriuretic peptide receptor 0.0068 0.0617 0.0579
Loa Loa (eye worm) hypothetical protein 0.0185 0.1956 0.1955
Echinococcus multilocularis hypothetical protein 0.0386 0.4256 0.4233
Loa Loa (eye worm) acetyltransferase 0.0154 0.1599 0.1598
Onchocerca volvulus 0.0068 0.0617 0.3101
Giardia lamblia Beta tubulin 0.0523 0.5819 1
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0158 0.1649 0.2784
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0018 0.0052 0.0104
Echinococcus multilocularis small conductance calcium activated potassium 0.0124 0.1262 0.1227
Schistosoma mansoni lamin 0.0026 0.0142 0.0123
Echinococcus granulosus beta tubulin 0.0523 0.5819 0.5802
Trypanosoma cruzi tubulin gamma chain 0.028 0.3036 0.5184
Onchocerca volvulus 0.0069 0.0628 0.3176
Echinococcus multilocularis tubulin gamma 1 chain 0.028 0.3036 0.3008
Loa Loa (eye worm) cytochrome P450 0.0018 0.0052 0.005
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0018 0.0052 0.0104
Trypanosoma cruzi tubulin delta chain 0.0121 0.1228 0.2056
Echinococcus multilocularis tubulin epsilon chain 0.028 0.3036 0.3008
Entamoeba histolytica hypothetical protein 0.0068 0.0617 0.0613
Schistosoma mansoni tubulin subunit alpha 0.0386 0.4256 0.4597
Toxoplasma gondii beta-1 tubulin, putative 0.0523 0.5819 1
Trichomonas vaginalis tubulin, putative 0.0523 0.5819 1
Schistosoma mansoni intermediate filament proteins 0.0026 0.0142 0.0123
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0018 0.0052 0.0026
Schistosoma mansoni tubulin subunit beta 0.0523 0.5819 0.6297
Mycobacterium ulcerans hypothetical protein 0.0069 0.0628 0.4953
Leishmania major cytochrome p450-like protein 0.0018 0.0052 0.0021
Leishmania major alpha tubulin 0.0386 0.4256 0.7296
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0068 0.0617 0.0579
Echinococcus granulosus lamin 0.0026 0.0142 0.0102
Toxoplasma gondii cytochrome p450 superfamily protein 0.0018 0.0052 0.009
Echinococcus granulosus metabotropic glutamate receptor 2 0.0605 0.6754 0.6741
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0018 0.0052 0.0104
Loa Loa (eye worm) hypothetical protein 0.0018 0.0045 0.0043
Loa Loa (eye worm) hypothetical protein 0.0068 0.0617 0.0615
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0154 0.1599 0.1708
Echinococcus multilocularis Tubulin beta 2C chain 0.0523 0.5819 0.5802
Plasmodium falciparum tubulin delta chain, putative 0.0121 0.1228 0.2056
Trichomonas vaginalis D-aminoacylase, putative 0.0069 0.0628 0.1018
Loa Loa (eye worm) tubulin alpha-2 chain 0.0386 0.4256 0.4255
Trichomonas vaginalis tubulin beta chain, putative 0.0386 0.4256 0.7296
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0018 0.0052 0.0104
Loa Loa (eye worm) glutamate receptor 0.0284 0.3087 0.3086
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0018 0.0052 0.0104
Brugia malayi Tubulin beta-1 chain 0.0523 0.5819 0.7189
Brugia malayi tubulin alpha-2 chain 0.0386 0.4256 0.5258
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0127 0.1296 1
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0018 0.0052 0.0104
Leishmania major beta tubulin 0.0523 0.5819 1
Trypanosoma brucei alpha tubulin, putative 0.0158 0.1649 0.2784
Echinococcus multilocularis musashi 0.0026 0.0142 0.0102
Echinococcus multilocularis tubulin subunit TubB 0.0386 0.4256 0.4233
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0038 0.0278 0.0239
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0036 0.0256 0.1821
Brugia malayi beta-lactamase family protein 0.0069 0.0628 0.0774
Loa Loa (eye worm) BEN-1 protein 0.0523 0.5819 0.5818
Brugia malayi hypothetical protein 0.0231 0.2477 0.3059
Echinococcus granulosus tubulin alpha chain 0.0386 0.4256 0.4233
Mycobacterium tuberculosis Probable lipase LipE 0.0069 0.0628 0.1218
Leishmania major alpha tubulin 0.0386 0.4256 0.7296
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0017 0.004 0.5
Echinococcus granulosus Tubulin beta 2C chain 0.0523 0.5819 0.5802
Trypanosoma brucei beta tubulin 0.0523 0.5819 1
Leishmania major beta tubulin 0.0523 0.5819 1
Loa Loa (eye worm) hypothetical protein 0.0265 0.2869 0.2868
Onchocerca volvulus 0.0158 0.1649 0.9833
Trichomonas vaginalis tubulin gamma chain, putative 0.028 0.3036 0.5184
Trypanosoma brucei trypanothione reductase 0.005 0.0415 0.0649
Loa Loa (eye worm) tubulin alpha chain 0.0386 0.4256 0.4255
Loa Loa (eye worm) tubulin alpha 2 0.0107 0.1062 0.106
Trypanosoma brucei beta tubulin 0.0523 0.5819 1
Trypanosoma cruzi cytochrome P450, putative 0.0036 0.0256 0.0374
Schistosoma mansoni tyrosine kinase 0.0068 0.0617 0.064
Giardia lamblia Alpha-tubulin 0.0386 0.4256 0.7296
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0018 0.0052 0.0026
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0114 0.115 0.8826
Brugia malayi acetyltransferase, GNAT family protein 0.0154 0.1599 0.1974
Trichomonas vaginalis tubulin beta chain, putative 0.0523 0.5819 1
Echinococcus granulosus geminin 0.0165 0.173 0.1697
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0069 0.0628 0.0652
Trypanosoma brucei beta tubulin 0.0523 0.5819 1
Echinococcus granulosus survival motor neuron protein 1 0.0231 0.2477 0.2447
Schistosoma mansoni metabotropic glutamate receptor 0.0605 0.6754 0.7313
Trichomonas vaginalis tubulin epsilon chain, putative 0.0386 0.4256 0.7296
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0018 0.0052 0.0104
Schistosoma mansoni tubulin subunit beta 0.0523 0.5819 0.6297
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0018 0.0052 0.0026
Loa Loa (eye worm) tubulin alpha 2 0.0265 0.2869 0.2868
Toxoplasma gondii alpha-tubulin I, putative 0.0386 0.4256 0.7314
Trypanosoma brucei beta tubulin 0.0523 0.5819 1
Schistosoma mansoni tubulin subunit alpha 0.0121 0.1228 0.1304
Loa Loa (eye worm) tubulin alpha chain 0.0386 0.4256 0.4255
Leishmania major alpha tubulin 0.0386 0.4256 0.7296
Leishmania major beta tubulin 0.0523 0.5819 1
Plasmodium vivax tubulin beta chain, putative 0.0523 0.5819 1
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0045 0.0358 0.0615
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0045 0.0358 0.0612
Brugia malayi metabotropic glutamate receptor subtype 5a (mGluR5a), putative 0.0654 0.7317 0.9041
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0018 0.0052 0.0104
Loa Loa (eye worm) hypothetical protein 0.005 0.0417 0.0415
Schistosoma mansoni tubulin subunit beta 0.0523 0.5819 0.6297
Trypanosoma cruzi zeta tubulin, putative 0.0121 0.1228 0.2056
Loa Loa (eye worm) hypothetical protein 0.0231 0.2477 0.2476
Echinococcus multilocularis tubulin, beta 4A class IVa 0.0523 0.5819 0.5802
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0018 0.0052 0.0021
Loa Loa (eye worm) hypothetical protein 0.0068 0.0617 0.0615
Echinococcus granulosus tubulin alpha chain 0.0386 0.4256 0.4233
Plasmodium falciparum tubulin beta chain 0.0523 0.5819 1
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0018 0.0052 0.0104
Echinococcus multilocularis tubulin alpha chain 0.0386 0.4256 0.4233

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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