Detailed information for compound 1592284

Basic information

Technical information
  • TDR Targets ID: 1592284
  • Name: S-[[(2R,3R)-8-oxo-2,3-di(phenyl)-1,4-dioxaspi ro[4.5]dec-9-en-6-yl]] benzenecarbothioate
  • MW: 442.526 | Formula: C27H22O4S
  • H donors: 0 H acceptors: 2 LogP: 4.72 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C1C=CC2(C(C1)SC(=O)c1ccccc1)O[C@@H]([C@H](O2)c1ccccc1)c1ccccc1
  • InChi: 1S/C27H22O4S/c28-22-16-17-27(23(18-22)32-26(29)21-14-8-3-9-15-21)30-24(19-10-4-1-5-11-19)25(31-27)20-12-6-2-7-13-20/h1-17,23-25H,18H2/t23?,24-,25-/m1/s1
  • InChiKey: DCHHJPQHOLRHPT-OPWSDZRHSA-N  


Substructure search Similarity search

Network

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Synonyms

  • benzenecarbothioic acid S-[[(2R,3R)-8-oxo-2,3-di(phenyl)-1,4-dioxaspiro[4.5]dec-9-en-6-yl]] ester
  • thiobenzoic acid S-[[(2R,3R)-8-keto-2,3-di(phenyl)-1,4-dioxaspiro[4.5]dec-9-en-6-yl]] ester
  • NSC720706
  • NCI60_041366

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0059 0.0583 0.0586
Echinococcus granulosus tubulin delta chain 0.02 0.241 0.2421
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0029 0.0021
Echinococcus multilocularis musashi 0.0026 0.0157 0.0149
Giardia lamblia Beta tubulin 0.0779 0.9931 1
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0116 0.1324 0.231
Schistosoma mansoni hypothetical protein 0.0016 0.002 0.0019
Loa Loa (eye worm) hypothetical protein 0.0048 0.044 0.0443
Loa Loa (eye worm) tubulin gamma chain 0.0462 0.5819 0.586
Loa Loa (eye worm) tubulin beta chain 0.0779 0.9931 1
Loa Loa (eye worm) ctsf protein 0.0016 0.0029 0.0029
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0116 0.0279
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0064 0.0647 0.0645
Loa Loa (eye worm) tubulin beta-2A chain 0.0779 0.9931 1
Trichomonas vaginalis DNA helicase recq1, putative 0.004 0.0335 0.033
Leishmania major gamma-tubulin 0.0462 0.5819 0.5857
Trichomonas vaginalis tubulin gamma chain, putative 0.0462 0.5819 0.5857
Schistosoma mansoni tyrosine kinase 0.0096 0.1063 0.1069
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0067 0.0688 0.0693
Loa Loa (eye worm) cysteine protease 0.0016 0.0029 0.0029
Trichomonas vaginalis tubulin beta chain, putative 0.058 0.7342 0.7392
Leishmania major beta tubulin 0.0779 0.9931 1
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0449 0.5651 1
Leishmania major alpha tubulin 0.058 0.7342 0.7392
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0036 0.0283 0.0277
Echinococcus granulosus eukaryotic initiation factor 4A 0.0024 0.0126 0.0119
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.0024 0.0017
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0036 0.0283 0.0261
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0037 0.0297 0.0299
Loa Loa (eye worm) hypothetical protein 0.0082 0.0878 0.0884
Echinococcus granulosus neuroglian 0.0023 0.0119 0.0112
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0029 0.0021
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0024 0.0023
Loa Loa (eye worm) hypothetical protein 0.0016 0.002 0.0021
Mycobacterium tuberculosis Conserved protein 0.007 0.0731 0.1257
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0056 0.055 0.0552
Entamoeba histolytica protein kinase, putative 0.0034 0.0254 0.0254
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0016 0.002 0.0013
Trypanosoma cruzi epsilon tubulin, putative 0.0462 0.5814 0.5854
Brugia malayi Cathepsin L-like precursor 0.0016 0.0029 0.0029
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0067 0.0688 0.0681
Loa Loa (eye worm) hypothetical protein 0.0026 0.0157 0.0158
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0016 0.0029 0.0029
Leishmania major alpha tubulin 0.058 0.7342 0.7392
Toxoplasma gondii cathepsin CPL 0.0016 0.0029 0.0027
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0046 0.0422 0.0414
Entamoeba histolytica tubulin alpha chain, putative 0.058 0.7342 0.7393
Leishmania major hypothetical protein, conserved 0.007 0.0731 0.0729
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0035 0.0268 0.0262
Echinococcus granulosus tubulin subunit beta 0.0779 0.9931 1
Plasmodium falciparum tubulin gamma chain 0.0462 0.5819 0.585
Brugia malayi Nuclear hormone receptor E75 0.0032 0.0229 0.023
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.062 0.0617
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.0283 0.0283
Loa Loa (eye worm) TK protein kinase 0.0034 0.0254 0.0255
Loa Loa (eye worm) hypothetical protein 0.0054 0.0519 0.0522
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0116 0.0279
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0067 0.0688 0.0691
Echinococcus multilocularis transfer RNA-Lys 0.0035 0.0271 0.0263
Trichomonas vaginalis PIKK family atypical protein kinase 0.0023 0.0123 0.0116
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0018 0.0056 0.0048
Loa Loa (eye worm) hypothetical protein 0.0026 0.0151 0.0152
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0112 0.0089
Entamoeba histolytica tubulin family protein 0.0779 0.9931 1
Loa Loa (eye worm) hypothetical protein 0.0032 0.0229 0.023
Brugia malayi beta-lactamase 0.007 0.0731 0.0737
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0023 0.0112 0.0368
Echinococcus multilocularis tubulin delta chain 0.02 0.241 0.2404
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0023 0.0116 0.0279
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.007 0.0731 0.1257
Brugia malayi tubulin alpha-2 chain 0.058 0.7342 0.7394
Toxoplasma gondii beta-tubulin, putative 0.0779 0.9931 1
Echinococcus multilocularis follistatin 0.0037 0.0297 0.0289
Schistosoma mansoni tyrosine kinase 0.0018 0.0056 0.0054
Loa Loa (eye worm) beta-tubulin 0.0779 0.9931 1
Plasmodium vivax vivapain-2 0.0016 0.0029 0.0005
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0046 0.0422 0.0417
Loa Loa (eye worm) hypothetical protein 0.0024 0.0126 0.0127
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0267 0.0262
Schistosoma mansoni hypothetical protein 0.0047 0.0424 0.0425
Echinococcus multilocularis insulin receptor 0.0096 0.1063 0.1056
Leishmania major alpha tubulin 0.058 0.7342 0.7392
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0043 0.0383 0.0378
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0116 0.0279
Schistosoma mansoni nuclear hormone receptor 0.0032 0.0229 0.0228
Onchocerca volvulus 0.0067 0.0688 0.1802
Trichomonas vaginalis tubulin beta chain, putative 0.058 0.7342 0.7392
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.008 0.0863 0.0867
Brugia malayi PAS domain containing protein 0.0047 0.0429 0.0432
Trypanosoma brucei tubulin gamma chain 0.0462 0.5819 0.5857
Treponema pallidum NADH oxidase 0.0016 0.0024 0.0094
Schistosoma mansoni lamin 0.0026 0.0157 0.0157
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0026 0.0157 0.0158
Echinococcus multilocularis beta tubulin 0.0779 0.9931 0.9931
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.062 0.0617
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0023 0.0112 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0036 0.0283 0.0277
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0055 0.0539 0.0531
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0127 0.1466 0.146
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.062 0.0617
Echinococcus multilocularis beta LACTamase domain containing family member 0.007 0.0731 0.0724
Loa Loa (eye worm) hypothetical protein 0.0017 0.0041 0.0041
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0049 0.0457 0.046
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0023 0.0112 0.0267
Leishmania major alpha tubulin 0.058 0.7342 0.7392
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0024 0.0126 0.0119
Echinococcus granulosus neuropeptide receptor A26 0.0456 0.5734 0.5771
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0043 0.0383 0.0384
Echinococcus granulosus follistatin 0.0037 0.0297 0.0291
Echinococcus granulosus tubulin gamma 1 chain 0.0462 0.5819 0.5857
Echinococcus granulosus epidermal growth factor receptor 0.0292 0.3611 0.3632
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0238 0.0232
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0043 0.0383 0.0378
Brugia malayi nuclear hormone receptor family member nhr-6 0.0032 0.0229 0.023
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.007 0.0731 0.0737
Echinococcus granulosus organic anion transporting polypeptide 30B 0.0054 0.0519 0.0515
Mycobacterium tuberculosis Probable lipase LipD 0.007 0.0731 0.1257
Entamoeba histolytica hypothetical protein 0.0023 0.0112 0.0111
Echinococcus multilocularis FTZ F1 alpha 0.0067 0.0688 0.0681
Mycobacterium ulcerans beta-lactamase 0.007 0.0731 0.2147
Trichomonas vaginalis PIKK family atypical protein kinase 0.0023 0.0123 0.0116
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0046 0.0422 0.0414
Loa Loa (eye worm) hypothetical protein 0.0032 0.0229 0.023
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0237 0.2889 0.2903
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0055 0.0539 0.1563
Schistosoma mansoni tyrosine kinase 0.0096 0.1063 0.1069
Schistosoma mansoni lamin 0.0026 0.0157 0.0157
Echinococcus granulosus peroxisome assembly protein 26 0.058 0.7342 0.7392
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0104 0.1173 0.4616
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0031 0.0219 0.0213
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0016 0.0029 0.0021
Leishmania major eukaryotic initiation factor 4a, putative 0.0024 0.0126 0.0119
Trichomonas vaginalis tubulin beta chain, putative 0.058 0.7342 0.7392
Brugia malayi Bloom's syndrome protein homolog 0.004 0.0335 0.0338
Leishmania major epsilon tubulin, putative 0.0462 0.5814 0.5852
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0016 0.002 0.0013
Schistosoma mansoni steroid hormone receptor ad4bp 0.0067 0.0688 0.0691
Trypanosoma brucei beta tubulin 0.0779 0.9931 1
Brugia malayi Isocitrate dehydrogenase 0.0031 0.0219 0.0221
Plasmodium vivax tubulin beta chain, putative 0.0779 0.9931 1
Leishmania major cathepsin L-like protease 0.0016 0.0029 0.0021
Leishmania major beta tubulin 0.0779 0.9931 1
Toxoplasma gondii ABC1 family protein 0.007 0.0731 0.0735
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0101 0.1125 0.1118
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0436 0.548 0.5518
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0017 0.0041 0.0051
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0067 0.0688 0.0681
Loa Loa (eye worm) hypothetical protein 0.002 0.0081 0.0082
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0055 0.0539 0.0535
Trichomonas vaginalis tubulin alpha chain, putative 0.0779 0.9931 1
Schistosoma mansoni tubulin subunit beta 0.0779 0.9931 1
Brugia malayi Immunoglobulin I-set domain containing protein 0.0104 0.1163 0.1171
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0152 0.0146
Onchocerca volvulus Bile acid receptor homolog 0.0067 0.0688 0.1802
Leishmania major beta tubulin 0.0779 0.9931 1
Loa Loa (eye worm) hypothetical protein 0.0101 0.1131 0.1139
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0511 0.6456 0.6453
Echinococcus multilocularis neuroglian 0.0023 0.0119 0.0111
Echinococcus multilocularis transcription factor Dp 1 0.0037 0.0298 0.0291
Loa Loa (eye worm) hypothetical protein 0.0067 0.0688 0.0693
Echinococcus multilocularis sterol regulatory element binding protein 0.0083 0.089 0.0883
Brugia malayi hypothetical protein 0.0032 0.0229 0.023
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0022 0.0105 0.0097
Loa Loa (eye worm) hypothetical protein 0.0049 0.0457 0.046
Schistosoma mansoni nuclear hormone receptor 0.0067 0.0688 0.0691
Schistosoma mansoni hypothetical protein 0.0016 0.002 0.0019
Brugia malayi Nuclear hormone receptor E75 0.0032 0.0229 0.023
Loa Loa (eye worm) hypothetical protein 0.0026 0.0157 0.0158
Loa Loa (eye worm) hypothetical protein 0.0032 0.0229 0.023
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0035 0.0278 0.0278
Echinococcus multilocularis c src tyrosine kinase 0.0018 0.0056 0.0048
Trichomonas vaginalis tubulin alpha chain, putative 0.0237 0.2889 0.2903
Brugia malayi hypothetical protein 0.0032 0.0231 0.0233
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.038 0.4751 0.478
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0083 0.089 0.0896
Plasmodium falciparum ataxin-2 like protein, putative 0.0049 0.0458 0.0437
Loa Loa (eye worm) isocitrate dehydrogenase 0.0031 0.0219 0.0221
Schistosoma mansoni tyrosine kinase 0.0046 0.0422 0.0423
Trichomonas vaginalis DNA helicase recq, putative 0.003 0.0211 0.0204
Echinococcus granulosus neuropeptide s receptor 0.0456 0.5734 0.5771
Trichomonas vaginalis PIKK family atypical protein kinase 0.0023 0.0123 0.0116
Brugia malayi sulfakinin receptor protein 0.0216 0.2624 0.2642
Trichomonas vaginalis tubulin gamma chain, putative 0.0462 0.5814 0.5852
Loa Loa (eye worm) hypothetical protein 0.0054 0.0519 0.0522
Loa Loa (eye worm) hypothetical protein 0.038 0.4751 0.4784
Loa Loa (eye worm) hypothetical protein 0.0032 0.0229 0.023
Trichomonas vaginalis tubulin gamma chain, putative 0.02 0.241 0.2421
Brugia malayi protein-tyrosine kinase 0.004 0.0339 0.0341
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0037 0.0297 0.0299
Plasmodium vivax hypothetical protein, conserved 0.007 0.0731 0.0714
Echinococcus granulosus epidermal growth factor receptor 0.0159 0.1879 0.1885
Loa Loa (eye worm) hypothetical protein 0.0046 0.0416 0.0419
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0043 0.0383 0.0384
Trypanosoma cruzi cruzipain precursor, putative 0.0062 0.062 0.0622
Mycobacterium ulcerans hypothetical protein 0.0023 0.0116 0.0279
Trypanosoma cruzi tubulin gamma chain 0.0462 0.5819 0.5859
Echinococcus multilocularis eukaryotic initiation factor 4A III 0.0024 0.0126 0.0118
Echinococcus multilocularis tyrosine protein kinase Srms 0.004 0.0339 0.0331
Giardia lamblia Alpha-tubulin 0.058 0.7342 0.7387
Brugia malayi Integrin beta pat-3 precursor 0.0303 0.3751 0.3777
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0028 0.0189 0.019
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0023 0.0112 0.0156
Giardia lamblia Sgs1 DNA helicase, putative 0.0028 0.0178 0.0155
Brugia malayi Thioredoxin reductase 0.0046 0.0412 0.0415
Leishmania major beta tubulin 0.0779 0.9931 1
Echinococcus multilocularis Tubulin alpha 1 chain 0.058 0.7342 0.734
Loa Loa (eye worm) hypothetical protein 0.0037 0.0297 0.0299
Leishmania major delta tubulin, putative 0.0361 0.4505 0.4532
Loa Loa (eye worm) hypothetical protein 0.0067 0.0688 0.0693
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0064 0.0647 0.0652
Echinococcus granulosus tubulin alpha chain 0.058 0.7342 0.7392
Trichomonas vaginalis tubulin, putative 0.0779 0.9931 1
Toxoplasma gondii beta tubulin 0.0779 0.9931 1
Echinococcus multilocularis isocitrate dehydrogenase 0.0031 0.0219 0.0211
Mycobacterium tuberculosis Conserved protein 0.007 0.0731 0.1257
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0016 0.0024 0.0023
Loa Loa (eye worm) hypothetical protein 0.0054 0.0519 0.0522
Loa Loa (eye worm) hypothetical protein 0.007 0.0731 0.0737
Leishmania major alpha tubulin 0.058 0.7342 0.7392
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0031 0.0219 0.0213
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0016 0.0029 0.0021
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0029 0.0021
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0031 0.0219 0.0211
Schistosoma mansoni tyrosine kinase 0.0101 0.1125 0.1132
Schistosoma mansoni tubulin subunit beta 0.0779 0.9931 1
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0023 0.0116 0.0018
Trypanosoma brucei Eukaryotic initiation factor 4A-1 0.0024 0.0126 0.0119
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0032 0.0229 0.0221
Loa Loa (eye worm) hypothetical protein 0.0067 0.0688 0.0693
Leishmania major alpha tubulin 0.058 0.7342 0.7392
Brugia malayi bHLH-PAS transcription factor 0.0035 0.0271 0.0273
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0037 0.0297 0.0297
Schistosoma mansoni tyrosine kinase 0.0153 0.181 0.1821
Plasmodium vivax glutathione reductase, putative 0.0046 0.0412 0.0392
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0055 0.0539 0.0535
Loa Loa (eye worm) hypothetical protein 0.0032 0.0229 0.023
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.0116 0.0115
Leishmania major eukaryotic initiation factor 4a, putative 0.0024 0.0126 0.0119
Brugia malayi hypothetical protein 0.0032 0.0229 0.023
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0037 0.0297 0.0297
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0031 0.0219 0.0219
Loa Loa (eye worm) hypothetical protein 0.058 0.7342 0.7394
Echinococcus granulosus tubulin epsilon chain 0.0462 0.5814 0.5852
Echinococcus multilocularis ecdysone induced protein 78C 0.0067 0.0688 0.0681
Schistosoma mansoni tubulin subunit alpha 0.058 0.7342 0.7393
Trypanosoma cruzi tubulin delta chain 0.0361 0.4505 0.4536
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0197 0.0191
Leishmania major beta tubulin 0.0779 0.9931 1
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0043 0.0383 0.0378
Trichomonas vaginalis DNA helicase recq, putative 0.004 0.0335 0.033
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0023 0.0112 0.0111
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0035 0.0268 0.0262
Mycobacterium tuberculosis Probable esterase LipL 0.007 0.0731 0.1257
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0024 0.0127 0.0103
Plasmodium falciparum tubulin epsilon chain, putative 0.0462 0.5814 0.5845
Toxoplasma gondii histone lysine methyltransferase SET1 0.0053 0.0502 0.0504
Schistosoma mansoni hypothetical protein 0.0016 0.002 0.0019
Echinococcus granulosus tyrosine protein kinase Fyn 0.0046 0.0422 0.0417
Brugia malayi SRC-1 0.0046 0.0422 0.0425
Schistosoma mansoni tubulin subunit beta 0.0779 0.9931 1
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0116 0.0117
Trichomonas vaginalis tubulin beta chain, putative 0.0779 0.9931 1
Onchocerca volvulus 0.0048 0.044 0.1123
Trichomonas vaginalis tubulin epsilon chain, putative 0.058 0.7342 0.7392
Loa Loa (eye worm) RecQ helicase 0.004 0.0335 0.0338
Loa Loa (eye worm) kazal-type serine protease inhibitor domain-containing protein 0.0037 0.0297 0.0299
Loa Loa (eye worm) hypothetical protein 0.0023 0.0118 0.0118
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0023 0.0116 0.0163
Trypanosoma cruzi trypanothione reductase, putative 0.0046 0.0412 0.0413
Echinococcus multilocularis bloom syndrome protein 0.004 0.0335 0.0328
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.027 0.027
Mycobacterium ulcerans esterase/lipase LipP 0.007 0.0731 0.2147
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.0283 0.0277
Echinococcus multilocularis tubulin alpha 1C chain 0.058 0.7342 0.734
Toxoplasma gondii thioredoxin reductase 0.0046 0.0412 0.0413
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0029 0.0021
Loa Loa (eye worm) tubulin alpha-2 chain 0.058 0.7342 0.7394
Echinococcus multilocularis tubulin alpha chain 0.058 0.7342 0.734
Brugia malayi prostaglandin transporter 0.0054 0.0519 0.0522
Echinococcus multilocularis ubiquitin specific protease 41 0.0036 0.0283 0.0275
Trypanosoma brucei alpha tubulin 0.058 0.7342 0.7392
Loa Loa (eye worm) tubulin alpha 2 0.0143 0.1681 0.1693
Brugia malayi Nuclear hormone receptor-like 1 0.0035 0.0278 0.028
Trypanosoma cruzi Eukaryotic initiation factor 4A-1 0.0024 0.0126 0.0125
Schistosoma mansoni cpg binding protein 0.0029 0.02 0.0199
Echinococcus multilocularis eukaryotic initiation factor 4A 0.0024 0.0126 0.0118
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0035 0.0278 0.0272
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0018 0.0056 0.0054
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.003 0.0211 0.021
Brugia malayi sodium-independent organic anion transporter family protein 0.0054 0.0519 0.0522
Trichomonas vaginalis tubulin gamma chain, putative 0.0779 0.9931 1
Echinococcus multilocularis Tubulin alpha 1 chain 0.058 0.7342 0.734
Brugia malayi Cathepsin L-like precursor 0.0016 0.0029 0.0029
Echinococcus multilocularis tubulin alpha 1C chain 0.058 0.7342 0.734
Entamoeba histolytica recQ family helicase, putative 0.003 0.0211 0.021
Loa Loa (eye worm) hypothetical protein 0.0054 0.0519 0.0522
Trichomonas vaginalis tubulin beta chain, putative 0.058 0.7342 0.7392
Onchocerca volvulus 0.007 0.0731 0.1921
Loa Loa (eye worm) hypothetical protein 0.002 0.0081 0.0082
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0032 0.0229 0.0221
Loa Loa (eye worm) alpha-tubulin 0.058 0.7342 0.7394
Brugia malayi glutathione reductase 0.0046 0.0412 0.0415
Trypanosoma brucei hypothetical protein, conserved 0.0023 0.0112 0.0105
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0032 0.0229 0.0221
Echinococcus multilocularis cysteine protease 0.0016 0.0029 0.0021
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0029 0.0021
Brugia malayi eukaryotic initiation factor 4A 0.0024 0.0126 0.0127
Echinococcus granulosus single minded 2 0.0035 0.0271 0.0265
Loa Loa (eye worm) hypothetical protein 0.007 0.0731 0.0737
Loa Loa (eye worm) hypothetical protein 0.0032 0.0229 0.023
Schistosoma mansoni hypothetical protein 0.008 0.0851 0.0855
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0023 0.0116 0.0018
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0116 0.0109
Schistosoma mansoni hypothetical protein 0.0032 0.0231 0.0231
Echinococcus multilocularis integrin alpha ps 0.0066 0.0679 0.0672
Trichomonas vaginalis tubulin beta chain, putative 0.058 0.7342 0.7392
Echinococcus multilocularis tubulin alpha 0.0436 0.548 0.5477
Loa Loa (eye worm) hypothetical protein 0.0026 0.0159 0.016
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0122 0.1399 0.1393
Loa Loa (eye worm) BEN-1 protein 0.0779 0.9931 1
Echinococcus granulosus tyrosine protein kinase Src42A 0.0035 0.027 0.0264
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0104 0.1173 0.2041
Trichomonas vaginalis mercuric reductase, putative 0.0016 0.0024 0.0017
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0046 0.0422 0.0417
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0037 0.0297 0.0297
Echinococcus multilocularis cathepsin L cysteine protease 0.0016 0.0029 0.0021
Echinococcus multilocularis tyrosine protein kinase Fyn 0.004 0.0339 0.0331
Schistosoma mansoni hypothetical protein 0.0396 0.4954 0.4988
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0031 0.0219 0.0197
Loa Loa (eye worm) latrophilin receptor protein 2 0.0016 0.002 0.0021
Loa Loa (eye worm) hypothetical protein 0.008 0.0863 0.0869
Schistosoma mansoni tyrosine kinase 0.0153 0.181 0.1821
Schistosoma mansoni cathepsin F (C01 family) 0.0016 0.0029 0.0027
Toxoplasma gondii alpha tubulin TUBA1 0.058 0.7342 0.7393
Loa Loa (eye worm) hypothetical protein 0.0032 0.0229 0.023
Echinococcus granulosus tyrosine protein kinase Src42A 0.0046 0.0422 0.0417
Schistosoma mansoni cell adhesion molecule 0.0026 0.0156 0.0155
Trypanosoma brucei beta tubulin 0.0779 0.9931 1
Echinococcus granulosus tyrosine protein kinase Fyn 0.0046 0.0422 0.0417
Echinococcus granulosus Immunoglobulin 0.002 0.0081 0.0074
Echinococcus multilocularis neuropeptide s receptor 0.0456 0.5734 0.5731
Schistosoma mansoni zinc finger protein 0.0032 0.0229 0.0228
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0031 0.0219 0.0213
Entamoeba histolytica cysteine proteinase, putative 0.0016 0.0029 0.0027
Echinococcus granulosus integrin alpha ps 0.0066 0.0679 0.0677
Loa Loa (eye worm) hypothetical protein 0.0298 0.3686 0.3712
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.0116 0.0115
Schistosoma mansoni aryl hydrocarbon receptor 0.0047 0.0429 0.0431
Echinococcus granulosus eukaryotic initiation factor 4A III 0.0024 0.0126 0.0119
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.007 0.0731 0.0735
Echinococcus granulosus sterol regulatory element binding protein 0.0083 0.089 0.0889
Loa Loa (eye worm) MH2 domain-containing protein 0.0115 0.1318 0.1327
Loa Loa (eye worm) hypothetical protein 0.0017 0.0041 0.0041
Brugia malayi Integrin alpha pat-2 precursor 0.0148 0.1739 0.1751
Brugia malayi hypothetical protein 0.0035 0.0278 0.028
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0016 0.002 0.0013
Echinococcus granulosus L aminoadipate semialdehyde 0.008 0.0863 0.0861
Plasmodium falciparum eukaryotic initiation factor 4A 0.0024 0.0126 0.0102
Leishmania major hypothetical protein, conserved 0.0049 0.0458 0.0453
Trypanosoma brucei zeta tubulin 0.0469 0.5913 0.5951
Echinococcus granulosus tubulin subunit TubB 0.058 0.7342 0.7392
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0024 0.0023
Brugia malayi Tubulin gamma chain 0.0462 0.5819 0.586
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0023 0.0116 0.0163
Brugia malayi tubulin alpha chain - mouse 0.058 0.7342 0.7394
Brugia malayi Nuclear hormone receptor-like 1 0.0067 0.0688 0.0693
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0029 0.0021
Echinococcus multilocularis Tubulin beta 2C chain 0.0779 0.9931 0.9931
Echinococcus multilocularis thyroid hormone receptor alpha 0.0189 0.2268 0.2262
Plasmodium falciparum thioredoxin reductase 0.0046 0.0412 0.0392
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0028 0.0178 0.0155
Echinococcus multilocularis neuropeptide receptor A26 0.0456 0.5734 0.5731
Entamoeba histolytica hypothetical protein 0.0035 0.027 0.027
Trichomonas vaginalis tubulin epsilon chain, putative 0.058 0.7342 0.7392
Echinococcus multilocularis epidermal growth factor receptor 0.0292 0.3611 0.3606
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0067 0.0688 0.0693
Plasmodium falciparum alpha tubulin 1 0.058 0.7342 0.7387
Onchocerca volvulus 0.0032 0.0229 0.0546
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.062 0.0617
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0036 0.0283 0.0277
Trypanosoma brucei trypanothione reductase 0.0046 0.0412 0.0408
Brugia malayi Tubulin alpha chain 0.02 0.241 0.2427
Giardia lamblia Beta tubulin 0.0779 0.9931 1
Loa Loa (eye worm) hypothetical protein 0.0035 0.0267 0.0269
Brugia malayi hypothetical protein 0.0158 0.1868 0.1881
Entamoeba histolytica tubulin family protein 0.0779 0.9931 1
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0032 0.0229 0.0228
Loa Loa (eye worm) hypothetical protein 0.0229 0.2788 0.2807
Loa Loa (eye worm) hypothetical protein 0.007 0.0731 0.0737
Trypanosoma brucei beta tubulin 0.0779 0.9931 1
Echinococcus multilocularis beta tubulin 0.0779 0.9931 0.9931
Loa Loa (eye worm) nuclear hormone receptor 0.0032 0.0229 0.023
Echinococcus multilocularis geminin 0.0331 0.4115 0.411
Brugia malayi Tubulin beta-1 chain 0.0779 0.9931 1
Brugia malayi ecdysteroid receptor 0.0067 0.0688 0.0693
Echinococcus multilocularis Immunoglobulin 0.002 0.0081 0.0074
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0032 0.0229 0.0223
Brugia malayi ecdysone receptor 0.0032 0.0229 0.023
Plasmodium vivax thioredoxin reductase, putative 0.0046 0.0412 0.0392
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0035 0.0278 0.028
Loa Loa (eye worm) TK protein kinase 0.0104 0.1163 0.1171
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0099 0.1099 0.1092
Echinococcus granulosus lamin 0.0026 0.0157 0.0151
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0046 0.0422 0.0414
Echinococcus granulosus roundabout 2 0.0029 0.0193 0.0187
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0064 0.0647 0.065
Loa Loa (eye worm) TK/EGFR protein kinase 0.0292 0.3611 0.3637
Trichomonas vaginalis tubulin beta-1 chain, putative 0.02 0.241 0.2421
Loa Loa (eye worm) hypothetical protein 0.0016 0.0029 0.0029
Schistosoma mansoni tubulin subunit alpha 0.02 0.241 0.2426
Brugia malayi hypothetical protein 0.0054 0.0519 0.0522
Trichomonas vaginalis D-aminoacylase, putative 0.007 0.0731 0.0729
Leishmania major alpha tubulin 0.058 0.7342 0.7392
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.003 0.0211 0.0204
Onchocerca volvulus 0.0037 0.0297 0.0732
Echinococcus multilocularis tyrosine protein kinase HCK 0.0034 0.0254 0.0246
Loa Loa (eye worm) hypothetical protein 0.0083 0.089 0.0896
Loa Loa (eye worm) hypothetical protein 0.0032 0.0229 0.023
Giardia lamblia Epsilon tubulin 0.0225 0.2744 0.2746
Toxoplasma gondii LsmAD domain-containing protein 0.0049 0.0458 0.0459
Toxoplasma gondii tubulin, putative 0.0026 0.0153 0.0152
Trypanosoma cruzi MFS transporter, putative 0.0054 0.0519 0.0521
Echinococcus multilocularis Solute carrier organic anion transporter family 0.0054 0.0519 0.0511
Loa Loa (eye worm) hypothetical protein 0.0054 0.0519 0.0522
Loa Loa (eye worm) glutathione reductase 0.0046 0.0412 0.0415
Brugia malayi hypothetical protein 0.0035 0.027 0.0272
Echinococcus granulosus thyroid hormone receptor alpha 0.0032 0.0229 0.0223
Schistosoma mansoni glutaminase 0.027 0.3317 0.3339
Brugia malayi nuclear receptor RXR 0.0032 0.0229 0.023
Mycobacterium ulcerans cell division protein FtsZ 0.02 0.241 0.7246
Brugia malayi Niemann-Pick C1 protein precursor 0.0192 0.2315 0.2331
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0046 0.0422 0.0414
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0029 0.0021
Brugia malayi alpha-tubulin 0.058 0.7342 0.7394
Loa Loa (eye worm) steroid hormone receptor 0.0067 0.0688 0.0693
Echinococcus granulosus nuclear receptor nhr 48 0.0032 0.0229 0.0223
Trichomonas vaginalis conserved hypothetical protein 0.0083 0.089 0.0889
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0031 0.0219 0.0213
Trichomonas vaginalis D-aminoacylase, putative 0.007 0.0731 0.0729
Loa Loa (eye worm) hypothetical protein 0.0192 0.2315 0.2331
Echinococcus granulosus beta tubulin 0.0779 0.9931 1
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0067 0.0688 0.0681
Leishmania major beta tubulin 0.0779 0.9931 1
Leishmania major cathepsin L-like protease 0.0016 0.0029 0.0021
Schistosoma mansoni tubulin subunit alpha 0.058 0.7342 0.7393
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0036 0.0283 0.0285
Leishmania major cathepsin L-like protease 0.0016 0.0029 0.0021
Loa Loa (eye worm) hypothetical protein 0.0035 0.0278 0.028
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0028 0.0178 0.0179
Loa Loa (eye worm) tubulin beta-1 chain 0.0779 0.9931 1
Loa Loa (eye worm) hypothetical protein 0.0014 0.0002 0.0002
Schistosoma mansoni thyroid hormone receptor 0.0189 0.2268 0.2283
Loa Loa (eye worm) tubulin alpha chain 0.058 0.7342 0.7394
Onchocerca volvulus 0.0047 0.0424 0.1081
Echinococcus granulosus expressed conserved protein 0.0181 0.2163 0.2172
Leishmania major beta tubulin 0.0779 0.9931 1
Loa Loa (eye worm) hypothetical protein 0.0017 0.0041 0.0041
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0064 0.0647 0.065
Echinococcus multilocularis Niemann Pick C1 protein 0.0275 0.3386 0.3381
Echinococcus granulosus cathepsin l cysteine peptidase 0.0016 0.0029 0.0021
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0018 0.0056 0.0048
Echinococcus multilocularis nuclear receptor nhr 48 0.0032 0.0229 0.0221
Schistosoma mansoni tubulin subunit beta 0.0779 0.9931 1
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0021 0.0085 0.0078
Schistosoma mansoni hypothetical protein 0.0331 0.4115 0.4142
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.0283 0.0283
Onchocerca volvulus 0.0054 0.0519 0.134
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0018 0.0053 0.0045
Schistosoma mansoni cellular tumor antigen P53 0.0048 0.044 0.0441
Schistosoma mansoni integrin alpha-ps 0.0035 0.0267 0.0267
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0116 0.0109
Brugia malayi SPARC precursor 0.0037 0.0297 0.0299
Mycobacterium tuberculosis Probable oxidoreductase 0.0116 0.1324 0.231
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0116 0.0117
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0028 0.0178 0.0172
Trypanosoma brucei alpha tubulin 0.058 0.7342 0.7392
Trypanosoma cruzi cysteine peptidase, putative 0.0062 0.062 0.0622
Trypanosoma cruzi cysteine peptidase, putative 0.0062 0.062 0.0622
Trypanosoma cruzi cysteine peptidase, putative 0.0016 0.0029 0.0027
Echinococcus multilocularis tubulin alpha 3 chain 0.058 0.7342 0.734
Leishmania major beta tubulin 0.0779 0.9931 1
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.007 0.0731 0.2147
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0023 0.012 0.0113
Brugia malayi hypothetical protein 0.0216 0.2624 0.2642
Loa Loa (eye worm) hypothetical protein 0.0017 0.0041 0.0041
Echinococcus granulosus tubulin alpha 1C chain 0.058 0.7342 0.7392
Schistosoma mansoni hypothetical protein 0.0034 0.0255 0.0255
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0036 0.0283 0.0283
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0024 0.0126 0.0119
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.062 0.0617
Echinococcus granulosus fibroblast growth factor receptor 4 0.0101 0.1125 0.1126
Mycobacterium ulcerans lipase LipD 0.007 0.0731 0.2147
Loa Loa (eye worm) hypothetical protein 0.0035 0.0278 0.028
Onchocerca volvulus 0.0032 0.0229 0.0546
Brugia malayi tailless protein 0.0032 0.0229 0.023
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0067 0.0688 0.0691
Brugia malayi Intermediate filament tail domain containing protein 0.0026 0.0157 0.0158
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0064 0.0647 0.065
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0032 0.0229 0.0546
Schistosoma mansoni cathepsin F (C01 family) 0.0016 0.0029 0.0027
Echinococcus granulosus beta LACTamase domain containing family member 0.007 0.0731 0.0729
Trypanosoma brucei epsilon tubulin 0.0462 0.5814 0.5852
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0067 0.0688 0.0693
Loa Loa (eye worm) hypothetical protein 0.0017 0.0041 0.0041
Schistosoma mansoni tubulin subunit delta 0.02 0.241 0.2426
Loa Loa (eye worm) hypothetical protein 0.0082 0.0878 0.0884
Schistosoma mansoni hypothetical protein 0.01 0.1117 0.1124
Schistosoma mansoni blooms syndrome DNA helicase 0.0026 0.0152 0.0151
Loa Loa (eye worm) phosphatidylinositol 3 0.0015 0.0008 0.0008
Brugia malayi Tyrosine-protein kinase abl-1 0.0095 0.1046 0.1053
Brugia malayi Integrin alpha cytoplasmic region family protein 0.0112 0.1271 0.128
Echinococcus multilocularis survival motor neuron protein 1 0.0229 0.2788 0.2782
Brugia malayi Fibronectin type III domain containing protein 0.0023 0.0118 0.0118
Echinococcus granulosus ubiquitin specific protease 41 0.0036 0.0283 0.0277
Schistosoma mansoni nephrin 0.0026 0.0155 0.0154
Trichomonas vaginalis glutathione reductase, putative 0.0016 0.0024 0.0017
Trichomonas vaginalis tubulin alpha chain, putative 0.0237 0.2889 0.2903
Trypanosoma cruzi hypothetical protein, conserved 0.007 0.0731 0.0735
Plasmodium vivax tubulin epsilon chain, putative 0.0462 0.5814 0.5845
Echinococcus multilocularis hypothetical protein 0.058 0.7342 0.734
Schistosoma mansoni tyrosine kinase 0.0153 0.181 0.1821
Trichomonas vaginalis penicillin-binding protein, putative 0.007 0.0731 0.0729
Echinococcus granulosus tubulin alpha 3 chain 0.058 0.7342 0.7392
Onchocerca volvulus 0.0054 0.0519 0.134
Trypanosoma cruzi hypothetical protein, conserved 0.007 0.0731 0.0735
Loa Loa (eye worm) hypothetical protein 0.0032 0.0231 0.0233
Loa Loa (eye worm) hypothetical protein 0.0067 0.0688 0.0693
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0023 0.0116 0.0279
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.062 0.0617
Brugia malayi hypoxia-induced factor 1 0.0146 0.1709 0.1721
Leishmania major zeta tubulin, putative 0.0469 0.5913 0.5951
Loa Loa (eye worm) hypothetical protein 0.0049 0.0458 0.0461
Schistosoma mansoni nuclear receptor nhr-48 0.0032 0.0229 0.0228
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.062 0.0617
Loa Loa (eye worm) tubulin alpha chain 0.058 0.7342 0.7394
Loa Loa (eye worm) integrin alpha pat-2 0.0228 0.2778 0.2798
Schistosoma mansoni RAR-like nuclear receptor 0.0067 0.0688 0.0691
Toxoplasma gondii isocitrate dehydrogenase 0.0031 0.0219 0.0219
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0024 0.0023
Schistosoma mansoni hypothetical protein 0.008 0.0851 0.0855
Echinococcus granulosus Niemann Pick C1 protein 0.0192 0.2315 0.2325
Onchocerca volvulus Eukaryotic initiation factor 4A homolog 0.0024 0.0126 0.0265
Leishmania major cathepsin L-like protease 0.0062 0.062 0.0617
Schistosoma mansoni tyrosine kinase 0.0292 0.3611 0.3635
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.027 0.0263
Mycobacterium leprae cell division protein FtsZ 0.02 0.241 1
Loa Loa (eye worm) sodium-independent organic anion transporter 0.0054 0.0519 0.0522
Brugia malayi nuclear receptor NHR-67 0.0032 0.0229 0.023
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.003 0.0211 0.0204
Echinococcus granulosus agrin 0.0037 0.0297 0.0291
Schistosoma mansoni tyrosine kinase 0.0205 0.2477 0.2493
Onchocerca volvulus 0.007 0.0731 0.1921
Mycobacterium ulcerans putative regulatory protein 0.0035 0.0271 0.0748
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0037 0.0297 0.0299
Leishmania major alpha tubulin 0.058 0.7342 0.7392
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0029 0.0008
Echinococcus granulosus Nuclear hormone receptor HR96 0.0032 0.0229 0.0223
Leishmania major trypanothione reductase 0.0046 0.0412 0.0408
Loa Loa (eye worm) hypothetical protein 0.007 0.0731 0.0737
Giardia lamblia Delta tubulin 0.02 0.241 0.2408
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0067 0.0688 0.0693
Loa Loa (eye worm) agrin synaptic family protein 0.0037 0.0297 0.0299
Echinococcus granulosus tm gpcr rhodopsin 0.0511 0.6456 0.6498
Echinococcus multilocularis cathepsin L cysteine protease 0.0016 0.0029 0.0021
Trypanosoma brucei alpha tubulin 0.058 0.7342 0.7392
Loa Loa (eye worm) hypothetical protein 0.0035 0.0278 0.028
Leishmania major beta tubulin 0.0779 0.9931 1
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0036 0.0283 0.0283
Onchocerca volvulus Putative organic anion transporter 0.0054 0.0519 0.134
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0029 0.0021
Loa Loa (eye worm) hypothetical protein 0.0035 0.0278 0.028
Brugia malayi sodium-independent organic anion transporter family protein 0.0054 0.0519 0.0522
Onchocerca volvulus Protein ultraspiracle homolog 0.0067 0.0688 0.1802
Brugia malayi Kelch motif family protein 0.0046 0.0416 0.0419
Brugia malayi CHE-14 protein 0.0083 0.089 0.0896
Echinococcus granulosus Tubulin alpha 1 chain 0.058 0.7342 0.7392
Brugia malayi Nuclear hormone receptor-like 1 0.0035 0.0278 0.028
Schistosoma mansoni alpha tubulin 0.058 0.7342 0.7393
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0156 0.0149
Loa Loa (eye worm) hypothetical protein 0.0023 0.0118 0.0118
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0046 0.0422 0.0414
Loa Loa (eye worm) tubulin alpha 2 0.038 0.4751 0.4784
Toxoplasma gondii eukaryotic initiation factor-4A, putative 0.0024 0.0126 0.0125
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.0383 0.0378
Echinococcus granulosus c src tyrosine kinase 0.0018 0.0056 0.0048
Echinococcus multilocularis tubulin alpha 3 chain 0.058 0.7342 0.734
Echinococcus multilocularis tubulin subunit beta 0.0779 0.9931 0.9931
Plasmodium vivax tubulin alpha chain, putative 0.058 0.7342 0.7387
Schistosoma mansoni hypothetical protein 0.0122 0.1399 0.1407
Trichomonas vaginalis PIKK family atypical protein kinase 0.0023 0.0123 0.0116
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.007 0.0731 0.1257
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0195 0.2353 0.2368
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0211 0.2562 0.2557
Brugia malayi Tubulin alpha chain 0.058 0.7342 0.7394
Echinococcus multilocularis lamin dm0 0.0026 0.0157 0.0149
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0037 0.0297 0.0297
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0067 0.0688 0.0685
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0031 0.0219 0.0211
Leishmania major alpha tubulin 0.058 0.7342 0.7392
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0016 0.0029 0.0029
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0067 0.0688 0.0693
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0101 0.1125 0.1126
Schistosoma mansoni tubulin subunit beta 0.02 0.241 0.2426
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0029 0.0021
Toxoplasma gondii isocitrate dehydrogenase 0.0031 0.0219 0.0219
Echinococcus granulosus survival motor neuron protein 1 0.0229 0.2788 0.2801
Echinococcus multilocularis Tubulin alpha 1 chain 0.058 0.7342 0.734
Loa Loa (eye worm) hypothetical protein 0.0032 0.0229 0.023
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0067 0.0688 0.0693
Leishmania major beta tubulin 0.0779 0.9931 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0029 0.0021
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0023 0.0116 0.0279
Loa Loa (eye worm) TK/INSR protein kinase 0.0096 0.1063 0.1071
Schistosoma mansoni patched 1 0.0083 0.089 0.0894
Schistosoma mansoni survival motor neuron protein 0.0047 0.0424 0.0425
Plasmodium falciparum alpha tubulin 2 0.058 0.7342 0.7387
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0067 0.0688 0.0685
Echinococcus granulosus dnaJ subfamily B 0.0396 0.4954 0.4985
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0067 0.0688 0.0691
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0267 0.0262
Echinococcus granulosus tubulin alpha 0.0436 0.548 0.5515
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0017 0.0041 0.003
Leishmania major cysteine peptidase A (CPA) 0.0016 0.0029 0.0021
Echinococcus granulosus FTZ F1 alpha 0.0067 0.0688 0.0685
Brugia malayi Cathepsin L-like precursor 0.0016 0.0029 0.0029
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0029 0.0021
Leishmania major beta tubulin 0.0779 0.9931 1
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0052 0.049 0.0494
Loa Loa (eye worm) hypothetical protein 0.0067 0.0688 0.0693
Toxoplasma gondii beta-1 tubulin, putative 0.0779 0.9931 1
Onchocerca volvulus 0.0237 0.2889 0.7819
Onchocerca volvulus 0.0035 0.0271 0.0661
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0043 0.0383 0.0375
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0036 0.0283 0.0277
Leishmania major cathepsin L-like protease 0.0016 0.0029 0.0021
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0283 0.0277
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0022 0.0105 0.0098
Schistosoma mansoni DEAD box ATP-dependent RNA helicase 0.0024 0.0126 0.0125
Echinococcus multilocularis agrin 0.0037 0.0297 0.0289
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.058 0.7342 0.7392
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0267 0.0262
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0016 0.0029 0.0005
Echinococcus granulosus GPCR family 2 0.0016 0.002 0.0013
Schistosoma mansoni tubulin subunit beta 0.0779 0.9931 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0029 0.0021
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0067 0.0688 0.1802
Echinococcus multilocularis tubulin alpha chain 0.058 0.7342 0.734
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0016 0.0024 0.0025
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0116 0.1324 0.231
Echinococcus multilocularis tubulin alpha chain 0.058 0.7342 0.734
Trypanosoma cruzi trypanothione reductase, putative 0.0016 0.0024 0.0023
Brugia malayi nuclear receptor NHR-88 0.0067 0.0688 0.0693
Trichomonas vaginalis tubulin epsilon chain, putative 0.02 0.241 0.2421
Schistosoma mansoni alpha tubulin 0.058 0.7342 0.7393
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0017 0.0041 0.19
Brugia malayi nuclear receptor NHR-88 0.0032 0.0229 0.023
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0032 0.0229 0.0546
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0043 0.0383 0.0384
Brugia malayi nuclear receptor RXR 0.0035 0.0278 0.028
Trypanosoma cruzi target of rapamycin kinase 3 0.0035 0.0268 0.0268
Plasmodium vivax tubulin alpha chain, putative 0.058 0.7342 0.7387
Echinococcus multilocularis epidermal growth factor receptor 0.0159 0.1879 0.1872
Brugia malayi orphan nuclear receptor NR2E1 0.0032 0.0229 0.023
Trypanosoma cruzi major cysteine proteinase, putative 0.0049 0.0448 0.045
Trypanosoma brucei alpha tubulin, putative 0.0237 0.2889 0.2903
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0238 0.0232
Echinococcus granulosus Tubulin alpha 1 chain 0.058 0.7342 0.7392
Echinococcus granulosus Tubulin beta 2C chain 0.0779 0.9931 1
Mycobacterium tuberculosis Probable dehydrogenase 0.0104 0.1173 0.2041
Loa Loa (eye worm) tubulin alpha-3 chain 0.0343 0.4272 0.4302
Echinococcus granulosus tubulin alpha chain 0.058 0.7342 0.7392
Trypanosoma cruzi Eukaryotic initiation factor 4A-1 0.0024 0.0126 0.0125
Echinococcus multilocularis Tubulin beta 2C chain 0.0779 0.9931 0.9931
Onchocerca volvulus 0.0023 0.0116 0.0239
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0152 0.0146
Echinococcus multilocularis organic anion transporting polypeptide 30B 0.0054 0.0519 0.0511
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0015 0.0008 0.0008
Echinococcus multilocularis GPCR, family 2 0.0016 0.002 0.0013
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0029 0.0021
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0225 0.2744 0.2762
Brugia malayi photoreceptor-specific nuclear receptor 0.0067 0.0688 0.0693
Echinococcus granulosus alpha tubulin 0.058 0.7342 0.7392
Echinococcus granulosus twitchin 0.0023 0.0119 0.0112
Brugia malayi Tubulin beta chain 0.0237 0.2889 0.2909
Loa Loa (eye worm) hypothetical protein 0.0112 0.1271 0.128
Loa Loa (eye worm) tubulin beta-4 chain 0.0779 0.9931 1
Schistosoma mansoni agrin 0.0037 0.0297 0.0297
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0023 0.0112 0.0458
Plasmodium vivax ataxin-2 like protein, putative 0.0049 0.0458 0.0437
Giardia lamblia Gamma tubulin 0.0462 0.5819 0.585
Schistosoma mansoni tyrosine kinase 0.0046 0.0422 0.0423
Echinococcus granulosus tubulin alpha chain 0.058 0.7342 0.7392
Schistosoma mansoni retinoic acid receptor RXR 0.0162 0.1926 0.1938
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0029 0.0021
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0028 0.0178 0.017
Trypanosoma brucei epsilon tubulin 0.0462 0.5814 0.5852
Echinococcus granulosus thioredoxin glutathione reductase 0.0046 0.0412 0.0408
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0067 0.0688 0.0693
Loa Loa (eye worm) beta-lactamase 0.007 0.0731 0.0737
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.0024 0.0023
Brugia malayi Immunoglobulin I-set domain containing protein 0.0028 0.0189 0.019
Plasmodium falciparum glutathione reductase 0.0046 0.0412 0.0392
Mycobacterium ulcerans hypothetical protein 0.007 0.0731 0.2147
Schistosoma mansoni alpha tubulin 0.058 0.7342 0.7393
Echinococcus granulosus integrin alpha ps 0.0032 0.0231 0.0225
Loa Loa (eye worm) hypothetical protein 0.0023 0.0116 0.0117
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0029 0.0008
Schistosoma mansoni Neurotrimin precursor (hNT) 0.002 0.0081 0.008
Brugia malayi Immunoglobulin I-set domain containing protein 0.0023 0.0118 0.0118
Onchocerca volvulus 0.0054 0.0519 0.134
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0192 0.2315 0.2329
Trypanosoma cruzi alpha tubulin, putative 0.058 0.7342 0.7393
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0016 0.0024 0.0017
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0016 0.0024 0.0017
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0064 0.0647 0.0645
Echinococcus multilocularis Tubulin beta 2C chain 0.0779 0.9931 0.9931
Schistosoma mansoni hypothetical protein 0.008 0.0851 0.0855
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0035 0.0278 0.0278
Echinococcus granulosus tumor protein p63 0.0327 0.4061 0.4085
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0067 0.0688 0.0685
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0067 0.0688 0.0693
Echinococcus granulosus insulin receptor 0.0096 0.1063 0.1063
Trichomonas vaginalis PIKK family atypical protein kinase 0.0023 0.0123 0.0116
Loa Loa (eye worm) hypothetical protein 0.0034 0.0255 0.0257
Trichomonas vaginalis tubulin beta chain, putative 0.0237 0.2889 0.2903
Mycobacterium ulcerans glutaminase 0.027 0.3317 1
Brugia malayi Steroid receptor seven-up type 2 0.0067 0.0688 0.0693
Echinococcus multilocularis L aminoadipate semialdehyde 0.008 0.0863 0.0855
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0099 0.1099 0.11
Echinococcus multilocularis integrin beta 2 0.0224 0.2732 0.2726
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0104 0.1173 0.2041
Loa Loa (eye worm) tubulin alpha 2 0.038 0.4751 0.4784
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0067 0.0688 0.0691
Leishmania major beta tubulin 0.0779 0.9931 1
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0064 0.0647 0.064
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0015 0.0008 0.0006
Brugia malayi Tubulin beta chain 0.02 0.241 0.2427
Echinococcus granulosus cathepsin l1 0.0016 0.0029 0.0021
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0156 0.0149
Schistosoma mansoni organic anion transporter 0.0054 0.0519 0.0521
Brugia malayi Cell division protein ftsZ 0.02 0.241 0.2427
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0064 0.0647 0.0645
Mycobacterium leprae Probable lipase LipE 0.007 0.0731 0.2695
Mycobacterium leprae conserved hypothetical protein 0.007 0.0731 0.2695
Echinococcus granulosus tyrosine protein kinase Src64B 0.0046 0.0422 0.0417
Leishmania major beta tubulin 0.0779 0.9931 1
Loa Loa (eye worm) glutaminase 2 0.027 0.3317 0.334
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0067 0.0688 0.0693
Loa Loa (eye worm) hypothetical protein 0.0037 0.0297 0.0299
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0016 0.0029 0.0021
Toxoplasma gondii alpha-tubulin I, putative 0.058 0.7342 0.7393
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0029 0.0021
Echinococcus multilocularis expressed protein 0.0037 0.0297 0.0289
Echinococcus multilocularis lamin 0.0026 0.0157 0.0149
Plasmodium vivax vivapain-2 0.0016 0.0029 0.0005
Loa Loa (eye worm) hypothetical protein 0.0023 0.012 0.012
Brugia malayi Calcitonin receptor-like protein seb-1 0.0049 0.0457 0.046
Onchocerca volvulus 0.007 0.0731 0.1921
Brugia malayi nuclear hormone receptor family member odr-7 0.0032 0.0229 0.023
Echinococcus multilocularis protein dispatched 1 0.0094 0.1041 0.1034
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0101 0.1125 0.1118
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0028 0.0178 0.0177
Brugia malayi sodium-independent organic anion transporter family protein 0.0054 0.0519 0.0522
Echinococcus multilocularis tubulin beta 1 chain 0.0779 0.9931 0.9931
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0029 0.0021
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0238 0.0232
Brugia malayi secreted modular calcium-binding protein 1 0.0037 0.0297 0.0299
Schistosoma mansoni tubulin subunit epsilon 0.0462 0.5814 0.5854
Loa Loa (eye worm) alpha-tubulin 0.058 0.7342 0.7394
Brugia malayi intermediate filament protein 0.0026 0.0157 0.0158
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0028 0.0178 0.0179
Brugia malayi glutaminase DH11.1 0.027 0.3317 0.334
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0067 0.0688 0.0693
Loa Loa (eye worm) hypothetical protein 0.0216 0.2624 0.2642
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.062 0.0617
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.027 0.0265
Trypanosoma brucei alpha tubulin 0.058 0.7342 0.7392
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0016 0.002 0.0021
Plasmodium falciparum tubulin beta chain 0.0779 0.9931 1
Echinococcus granulosus integrin alpha 3 0.0113 0.129 0.1293
Brugia malayi hypothetical protein 0.0046 0.0416 0.0419
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0067 0.0688 0.0693
Schistosoma mansoni follistatin 0.0037 0.0297 0.0297
Schistosoma mansoni tyrosine kinase 0.0018 0.0056 0.0054
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0016 0.0024 0.0017
Schistosoma mansoni cpg binding protein 0.0029 0.02 0.0199
Plasmodium vivax delta tubulin, putative 0.02 0.241 0.2408
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0055 0.0539 0.0915
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.008 0.0863 0.0869
Echinococcus granulosus tyrosine protein kinase ABL1 0.0211 0.2562 0.2574
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0343 0.4272 0.4298
Plasmodium vivax acyl-CoA synthetase, putative 0.0017 0.0041 0.0017
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0267 0.0262
Leishmania major phosphopantetheinyl transferase-like protein 0.0023 0.0112 0.0105
Treponema pallidum ATP-dependent RNA helicase 0.0024 0.0126 0.0514
Loa Loa (eye worm) hypothetical protein 0.0054 0.0519 0.0522
Echinococcus multilocularis protein patched 0.0083 0.089 0.0883
Schistosoma mansoni integrin alpha-ps 0.0066 0.0679 0.0682
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0067 0.0688 0.0685
Onchocerca volvulus 0.0054 0.0519 0.134
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0361 0.4505 0.4536
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0032 0.0229 0.0221
Loa Loa (eye worm) hypothetical protein 0.0067 0.0688 0.0693
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0016 0.0024 0.0017
Entamoeba histolytica hypothetical protein 0.0035 0.027 0.027
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0067 0.0688 0.0693
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0032 0.0229 0.023
Toxoplasma gondii protease inhibitor PI2 0.0037 0.0297 0.0297
Mycobacterium tuberculosis Cell division protein FtsZ 0.02 0.241 0.424
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0029 0.0021
Mycobacterium tuberculosis Conserved protein 0.007 0.0731 0.1257
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0029 0.0008
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0023 0.0116 0.0279
Giardia lamblia Alpha-tubulin 0.058 0.7342 0.7387
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0267 0.0262
Mycobacterium tuberculosis Probable hydrolase 0.007 0.0731 0.1257
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0162 0.1926 0.1933
Schistosoma mansoni tubulin subunit alpha 0.058 0.7342 0.7393
Treponema pallidum cell division protein FtsZ 0.02 0.241 1
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0036 0.0283 0.0277
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0028 0.0178 0.0179
Trichomonas vaginalis D-aminoacylase, putative 0.007 0.0731 0.0729
Schistosoma mansoni hypothetical protein 0.008 0.0851 0.0855
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0067 0.0688 0.0693
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0023 0.0112 0.0111
Brugia malayi Tubulin alpha-2 chain 0.058 0.7342 0.7394
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0028 0.0178 0.0177
Plasmodium vivax RNA helicase-1, putative 0.0024 0.0126 0.0102
Loa Loa (eye worm) thioredoxin reductase 0.0046 0.0412 0.0415
Schistosoma mansoni DEAD box ATP-dependent RNA helicase 0.0024 0.0126 0.0125
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0043 0.0383 0.0384
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.0024 0.0017
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0029 0.0008
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0031 0.0219 0.0219
Onchocerca volvulus 0.0026 0.0157 0.0351
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0067 0.0688 0.0691
Leishmania major cathepsin L-like protease 0.0062 0.062 0.0617
Trichomonas vaginalis penicillin-binding protein, putative 0.007 0.0731 0.0729
Loa Loa (eye worm) BEN-1 protein 0.0779 0.9931 1
Mycobacterium tuberculosis Probable lipase LipE 0.007 0.0731 0.1257
Trypanosoma cruzi zeta tubulin, putative 0.0469 0.5913 0.5953
Trichomonas vaginalis PIKK family atypical protein kinase 0.0023 0.0123 0.0116
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0016 0.0029 0.0005
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0112 0.0089
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0156 0.0149
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0064 0.0647 0.065
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0179 0.018
Loa Loa (eye worm) hypothetical protein 0.002 0.0081 0.0082
Brugia malayi Cathepsin L-like precursor 0.0016 0.0029 0.0029
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.002 0.0081 0.008
Trichomonas vaginalis tubulin alpha chain, putative 0.0237 0.2889 0.2903
Trichomonas vaginalis tubulin, putative 0.0226 0.2749 0.2763
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0029 0.0021
Loa Loa (eye worm) integrin beta-2 0.0303 0.3751 0.3777
Schistosoma mansoni tubulin subunit beta 0.0779 0.9931 1
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0046 0.0422 0.0414
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0029 0.0021
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.03 0.0295
Echinococcus multilocularis cysteine protease 0.0016 0.0029 0.0021
Leishmania major beta tubulin 0.0779 0.9931 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0238 0.0232
Brugia malayi hypothetical protein 0.0298 0.3686 0.3712
Plasmodium falciparum tubulin delta chain, putative 0.02 0.241 0.2408
Echinococcus multilocularis Tubulin beta 2C chain 0.0779 0.9931 0.9931
Schistosoma mansoni hypothetical protein 0.0022 0.0105 0.0104
Trichomonas vaginalis tubulin alpha chain, putative 0.0436 0.548 0.5515
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0016 0.002 0.0013
Toxoplasma gondii transporter, major facilitator family protein 0.0054 0.0519 0.0521
Schistosoma mansoni vesicular amine transporter 0.002 0.0081 0.008
Trichomonas vaginalis conserved hypothetical protein 0.02 0.241 0.2421
Brugia malayi steroid hormone receptor 0.0067 0.0688 0.0693
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0067 0.0688 0.0693
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0067 0.0688 0.0693
Brugia malayi MH2 domain containing protein 0.0115 0.1318 0.1327
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0028 0.0178 0.0172
Loa Loa (eye worm) alpha-tubulin isotype 2 0.038 0.4751 0.4784
Entamoeba histolytica tubulin alpha-1 chain 0.058 0.7342 0.7393
Mycobacterium tuberculosis Probable cold-shock DeaD-box protein A homolog DeaD (ATP-dependent RNA helicase dead homolog) 0.0024 0.0126 0.018
Loa Loa (eye worm) kelch domain-containing protein family protein 0.0046 0.0416 0.0419
Onchocerca volvulus 0.0028 0.0179 0.0411
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0035 0.0278 0.027
Trypanosoma brucei epsilon tubulin 0.0436 0.548 0.5515
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0029 0.0021
Loa Loa (eye worm) transcription factor SMAD2 0.0115 0.1318 0.1327
Loa Loa (eye worm) hypothetical protein 0.007 0.0731 0.0737
Trichomonas vaginalis tubulin beta chain, putative 0.058 0.7342 0.7392
Echinococcus granulosus ecdysone induced protein 78C 0.0067 0.0688 0.0685
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.007 0.0731 0.0735
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0055 0.0539 0.0541
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0023 0.0112 0.0267
Echinococcus granulosus Tubulin beta 2C chain 0.0779 0.9931 1
Onchocerca volvulus 0.008 0.0863 0.2279
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0036 0.0283 0.0275
Brugia malayi Cathepsin L-like precursor 0.0016 0.0029 0.0029
Echinococcus granulosus Tubulin beta 2C chain 0.0779 0.9931 1
Loa Loa (eye worm) hypothetical protein 0.0032 0.0229 0.023
Schistosoma mansoni tubulin subunit gamma 0.0462 0.5819 0.5859
Echinococcus multilocularis Niemann Pick C1 protein 0.0192 0.2315 0.2309
Giardia lamblia Translation initiation factor eIF-4A, putative 0.0024 0.0126 0.0102
Echinococcus multilocularis tumor protein p63 0.0327 0.4061 0.4056
Trypanosoma brucei hypothetical protein, conserved 0.007 0.0731 0.0729
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0031 0.0219 0.0197
Echinococcus multilocularis tubulin gamma 1 chain 0.0462 0.5819 0.5816
Leishmania major beta tubulin 0.0779 0.9931 1
Trypanosoma brucei tubulin delta chain 0.0361 0.4505 0.4532
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0185 0.0178
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0028 0.0178 0.017
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0046 0.0422 0.0414
Loa Loa (eye worm) TK protein kinase 0.004 0.0339 0.0341
Echinococcus multilocularis basement membrane specific heparan sulfate 0.002 0.0081 0.0074
Schistosoma mansoni nuclear receptor 0.0032 0.0229 0.0228
Echinococcus multilocularis dnaJ subfamily B 0.0396 0.4954 0.495
Trypanosoma cruzi beta tubulin, putative 0.0779 0.9931 1
Echinococcus multilocularis tyrosine protein kinase Abl 0.0095 0.1046 0.1039
Schistosoma mansoni hypothetical protein 0.0016 0.002 0.0019
Brugia malayi Papain family cysteine protease containing protein 0.0016 0.0029 0.0029
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0104 0.1173 0.2041
Trypanosoma cruzi zeta tubulin, putative 0.0469 0.5913 0.5953
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0067 0.0688 0.0681
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0067 0.0688 0.0693
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0043 0.0383 0.0378
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0036 0.0283 0.0275
Echinococcus multilocularis tyrosine protein kinase Blk 0.004 0.0339 0.0331
Trichomonas vaginalis esterase, putative 0.007 0.0731 0.0729
Echinococcus multilocularis integrin alpha 3 0.0113 0.129 0.1284
Leishmania major alpha tubulin 0.058 0.7342 0.7392
Brugia malayi beta-lactamase family protein 0.007 0.0731 0.0737
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0067 0.0688 0.0681
Echinococcus multilocularis Tubulin beta 2C chain 0.0779 0.9931 0.9931
Echinococcus granulosus beta tubulin 0.0779 0.9931 1
Echinococcus granulosus tubulin alpha 3 chain 0.058 0.7342 0.7392
Brugia malayi hypothetical protein 0.0023 0.0118 0.0118
Schistosoma mansoni organic anion transporter 0.0054 0.0519 0.0521
Loa Loa (eye worm) hypothetical protein 0.0023 0.0116 0.0117
Brugia malayi nuclear hormone receptor 0.0032 0.0229 0.023
Plasmodium falciparum acyl-CoA synthetase 0.0017 0.0041 0.0017
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0238 0.0232
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0238 0.0232
Trypanosoma brucei PAB1-binding protein , putative 0.0049 0.0458 0.0453
Brugia malayi Latrophilin receptor protein 2 0.0016 0.002 0.0021
Loa Loa (eye worm) hypothetical protein 0.0023 0.0118 0.0118
Brugia malayi nuclear hormone receptor 0.0067 0.0688 0.0693
Schistosoma mansoni cpg binding protein 0.0028 0.0179 0.0179
Echinococcus multilocularis tubulin subunit TubB 0.058 0.7342 0.734
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0116 0.0109
Brugia malayi isocitrate dehydrogenase 0.0031 0.0219 0.0221
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0024 0.0023
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0016 0.0024 0.0017
Schistosoma mansoni hypothetical protein 0.0035 0.027 0.027
Toxoplasma gondii target of rapamycin (TOR), putative 0.0032 0.0238 0.0238
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0029 0.0021
Leishmania major beta tubulin 0.0779 0.9931 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0067 0.0688 0.0693
Echinococcus granulosus defective proboscis extension response 0.002 0.0081 0.0074
Brugia malayi Cathepsin L-like precursor 0.0016 0.0029 0.0029
Loa Loa (eye worm) hypothetical protein 0.0158 0.1868 0.1881
Plasmodium falciparum cysteine proteinase falcipain 3 0.0016 0.0029 0.0005
Trypanosoma brucei zeta tubulin, putative 0.0469 0.5913 0.5951
Trypanosoma cruzi PAB1-binding protein , putative 0.0049 0.0458 0.0459
Entamoeba histolytica DEAD/DEAH box helicase, putative 0.0024 0.0126 0.0125
Echinococcus multilocularis roundabout 2 0.0029 0.0193 0.0185
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0031 0.0219 0.0219
Echinococcus multilocularis thioredoxin glutathione reductase 0.0046 0.0412 0.0405
Trypanosoma cruzi cysteine peptidase, putative 0.0062 0.062 0.0622
Schistosoma mansoni intermediate filament proteins 0.0026 0.0157 0.0157
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0031 0.0219 0.0211
Brugia malayi conserved hypotetical protein 0.0032 0.0229 0.023
Onchocerca volvulus 0.0298 0.3686 1
Wolbachia endosymbiont of Brugia malayi cell division protein FtsZ 0.02 0.241 1
Echinococcus granulosus bloom syndrome protein 0.004 0.0335 0.033
Plasmodium falciparum ataxin-2 like protein, putative 0.0049 0.0458 0.0437
Entamoeba histolytica tubulin gamma chain 0.0462 0.5819 0.5859
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0024 0.0023
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0046 0.0422 0.0414
Leishmania major beta tubulin 0.0779 0.9931 1
Echinococcus granulosus Tubulin beta 2C chain 0.0779 0.9931 1
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0104 0.1173 0.2041
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0024 0.0126 0.0119
Echinococcus multilocularis peroxisome assembly protein 26 0.058 0.7342 0.734
Leishmania major alpha tubulin 0.058 0.7342 0.7392
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.0383 0.0378
Echinococcus multilocularis expressed conserved protein 0.0181 0.2163 0.2157
Echinococcus granulosus cathepsin L cysteine proteinase 0.0016 0.0029 0.0021
Schistosoma mansoni DNA helicase recq1 0.0028 0.0178 0.0177
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0015 0.0008 0.0006
Loa Loa (eye worm) fibroinase 0.0016 0.0029 0.0029
Schistosoma mansoni tyrosine kinase 0.0159 0.1879 0.189
Trichomonas vaginalis glutaminase, putative 0.027 0.3317 0.3335
Schistosoma mansoni integrin beta subunit 0.0178 0.2134 0.2148
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0116 0.1324 0.5274
Loa Loa (eye worm) glutaminase 0.027 0.3317 0.334
Loa Loa (eye worm) hypothetical protein 0.0067 0.0688 0.0693
Schistosoma mansoni tyrosine kinase 0.0159 0.1879 0.189
Echinococcus granulosus transcription factor Dp 1 0.0037 0.0298 0.0293
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.0024 0.0017
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0024 0.0023
Echinococcus granulosus tyrosine kinase 0.004 0.0339 0.0334
Schistosoma mansoni hypothetical protein 0.0331 0.4115 0.4142
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.004 0.0339 0.0334
Trichomonas vaginalis conserved hypothetical protein 0.02 0.241 0.2421
Echinococcus granulosus tyrosine protein kinase Blk 0.004 0.0339 0.0334
Trichomonas vaginalis tubulin epsilon chain, putative 0.0779 0.9931 1
Echinococcus granulosus cpg binding protein 0.0029 0.02 0.0193
Trichomonas vaginalis tubulin epsilon chain, putative 0.0779 0.9931 1
Loa Loa (eye worm) tubulin beta chain 0.02 0.241 0.2427
Echinococcus granulosus intermediate filament protein 0.0026 0.0157 0.0151
Loa Loa (eye worm) hypothetical protein 0.0054 0.0519 0.0522
Echinococcus granulosus tubulin beta 4A class IVa 0.0779 0.9931 1
Toxoplasma gondii NADPH-glutathione reductase 0.0016 0.0024 0.0023
Loa Loa (eye worm) TK/ABL protein kinase 0.0211 0.2562 0.258
Loa Loa (eye worm) hypothetical protein 0.0032 0.0229 0.023
Loa Loa (eye worm) hypothetical protein 0.0032 0.0229 0.023
Mycobacterium tuberculosis Probable reductase 0.0104 0.1173 0.2041
Onchocerca volvulus 0.0054 0.0519 0.134
Onchocerca volvulus 0.0026 0.0157 0.0351
Schistosoma mansoni thyroid hormone receptor 0.0189 0.2268 0.2283
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0047 0.0424 0.0427
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0067 0.0688 0.0685
Schistosoma mansoni integrin alpha 0.0148 0.1739 0.1749
Brugia malayi beta-tubulin, identical 0.0779 0.9931 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0023 0.0123 0.0116
Schistosoma mansoni DNA helicase recq5 0.0028 0.0178 0.0177
Brugia malayi hypothetical protein 0.0054 0.0519 0.0522
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0055 0.0539 0.0543
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0043 0.0383 0.0384
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0122 0.1399 0.1402
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0046 0.0412 0.069
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0032 0.0229 0.0223
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0067 0.0688 0.0691
Loa Loa (eye worm) hypothetical protein 0.0343 0.4272 0.4302
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0016 0.0024 0.0023
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0031 0.0219 0.0211
Leishmania major cathepsin L-like protease 0.0016 0.0029 0.0021
Brugia malayi Furin-like cysteine rich region family protein 0.0292 0.3611 0.3637
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.062 0.0617
Schistosoma mansoni nuclear hormone receptor 0.0032 0.0229 0.0228
Loa Loa (eye worm) hypothetical protein 0.0035 0.0278 0.028
Echinococcus granulosus tyrosine protein kinase Fyn 0.0046 0.0422 0.0417
Loa Loa (eye worm) hypothetical protein 0.0037 0.0297 0.0299
Echinococcus granulosus Tubulin alpha 1 chain 0.058 0.7342 0.7392
Brugia malayi Protein kinase domain containing protein 0.0096 0.1063 0.1071
Loa Loa (eye worm) hypoxia-induced factor 1 0.0146 0.1709 0.1721
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0031 0.0219 0.0346
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0023 0.012 0.0119
Loa Loa (eye worm) DR-78 0.0032 0.0229 0.023
Echinococcus granulosus integrin beta 2 0.0224 0.2732 0.2745
Leishmania major alpha tubulin 0.058 0.7342 0.7392
Trypanosoma cruzi epsilon tubulin, putative 0.0462 0.5814 0.5854
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0037 0.0297 0.0299
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0049 0.0457 0.046
Schistosoma mansoni single-minded 0.0047 0.0429 0.0431
Trypanosoma cruzi tubulin delta chain 0.0361 0.4505 0.4536
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0055 0.0539 0.1563
Brugia malayi hypothetical protein 0.0049 0.0458 0.0461
Giardia lamblia GTOR 0.0043 0.0383 0.0362
Echinococcus granulosus Protein patched homolog 1 0.0083 0.089 0.0889
Echinococcus granulosus tyrosine protein kinase Lyn 0.0046 0.0422 0.0417
Brugia malayi hypothetical protein 0.0229 0.2788 0.2807
Entamoeba histolytica hypothetical protein 0.0035 0.027 0.027
Loa Loa (eye worm) SRC-1 0.0046 0.0422 0.0425
Schistosoma mansoni nuclear receptor 0.0032 0.0229 0.0228
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0043 0.0383 0.0386
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0035 0.027 0.0262
Loa Loa (eye worm) hypothetical protein 0.0032 0.0229 0.023
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.0024 0.0017
Brugia malayi hypothetical protein 0.0035 0.0278 0.028
Onchocerca volvulus Putative organic anion transporter 0.0054 0.0519 0.134
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0037 0.0303 0.0281
Echinococcus multilocularis cpg binding protein 0.0029 0.02 0.0192
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0238 0.0232
Entamoeba histolytica acyl-coA synthetase, putative 0.0023 0.0116 0.0115
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0029 0.0021
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0032 0.0229 0.023
Trypanosoma cruzi PAB1-binding protein , putative 0.0049 0.0458 0.0459
Trypanosoma brucei beta tubulin 0.0436 0.548 0.5515
Brugia malayi Tyrosine-protein kinase abl-1 0.0123 0.1418 0.1428
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0029 0.0021
Echinococcus multilocularis tubulin alpha chain 0.058 0.7342 0.734
Entamoeba histolytica hypothetical protein 0.0035 0.027 0.027
Giardia lamblia Beta tubulin 0.0779 0.9931 1
Trichomonas vaginalis tubulin, putative 0.0237 0.2889 0.2903
Loa Loa (eye worm) hypothetical protein 0.0023 0.0116 0.0117
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0067 0.0688 0.0693
Echinococcus multilocularis tubulin, beta 4A class IVa 0.0779 0.9931 0.9931
Echinococcus granulosus lamin dm0 0.0026 0.0157 0.0151
Mycobacterium tuberculosis Probable conserved lipoprotein 0.007 0.0731 0.1257
Echinococcus granulosus tyrosine protein kinase HCK 0.0034 0.0254 0.0248
Loa Loa (eye worm) phosphatidylinositol 3 0.0043 0.0383 0.0386
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.062 0.0617
Loa Loa (eye worm) hypothetical protein 0.0067 0.0688 0.0693
Loa Loa (eye worm) hypothetical protein 0.007 0.0731 0.0737
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0016 0.0029 0.0021
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.007 0.0731 0.0737
Brugia malayi beta-lactamase family protein 0.007 0.0731 0.0737
Loa Loa (eye worm) intermediate filament protein 0.0026 0.0157 0.0158
Loa Loa (eye worm) hypothetical protein 0.0026 0.0157 0.0158
Echinococcus multilocularis integrin alpha ps 0.0066 0.0679 0.0672
Entamoeba histolytica cysteine proteinase, putative 0.0016 0.0029 0.0027
Brugia malayi CXXC zinc finger family protein 0.0028 0.0179 0.018
Trichomonas vaginalis tubulin, putative 0.0237 0.2889 0.2903
Echinococcus granulosus tubulin alpha 1C chain 0.058 0.7342 0.7392
Echinococcus multilocularis integrin alpha ps 0.0032 0.0231 0.0224
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0015 0.0008 0.0006
Brugia malayi latrophilin 2 splice variant baaae 0.0034 0.0255 0.0257
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0067 0.0688 0.0685
Echinococcus granulosus tubulin alpha chain 0.058 0.7342 0.7392
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.0383 0.0378
Plasmodium vivax tubulin gamma chain, putative 0.0462 0.5819 0.585
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0036 0.0283 0.0283
Loa Loa (eye worm) hypothetical protein 0.0037 0.0297 0.0299
Onchocerca volvulus Putative organic anion transporter 0.0054 0.0519 0.134
Echinococcus granulosus tubulin alpha chain 0.058 0.7342 0.7392
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.062 0.0617
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0064 0.0647 0.0652
Echinococcus granulosus tubulin beta 1 chain 0.0779 0.9931 1
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0067 0.0688 0.0693
Trypanosoma brucei beta tubulin 0.0779 0.9931 1
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0159 0.1879 0.1885
Echinococcus granulosus geminin 0.0331 0.4115 0.4139
Loa Loa (eye worm) hypothetical protein 0.0028 0.0178 0.0179
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0046 0.0422 0.0414
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0043 0.0383 0.0378
Echinococcus granulosus Tubulin beta 2C chain 0.0779 0.9931 1
Echinococcus granulosus Niemann Pick C1 protein 0.0275 0.3386 0.3404
Entamoeba histolytica cysteine protease, putative 0.0016 0.0029 0.0027
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0016 0.0024 0.0017
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0032 0.0229 0.0228
Leishmania major cathepsin L-like protease 0.0062 0.062 0.0617
Brugia malayi Tubulin alpha-2 chain 0.058 0.7342 0.7394
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0116 0.0117
Schistosoma mansoni coup transcription factor 0.0067 0.0688 0.0691
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0067 0.0688 0.0693
Echinococcus multilocularis 0.0089 0.0978 0.0971
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.0024 0.0023
Loa Loa (eye worm) hypothetical protein 0.0116 0.1326 0.1335
Leishmania major beta tubulin 0.0779 0.9931 1
Echinococcus granulosus Nuclear hormone receptor HR96 0.0032 0.0229 0.0223
Loa Loa (eye worm) hypothetical protein 0.0036 0.0283 0.0285
Echinococcus multilocularis tubulin alpha chain 0.058 0.7342 0.734
Echinococcus multilocularis Immunoglobulin 0.002 0.0081 0.0074
Echinococcus granulosus Solute carrier organic anion transporter family 0.0054 0.0519 0.0515
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0067 0.0688 0.0681
Loa Loa (eye worm) nuclear receptor NHR-67 0.0032 0.0229 0.023
Echinococcus multilocularis tubulin epsilon chain 0.0462 0.5814 0.5811

Activities

Activity type Activity value Assay description Source Reference
GI50 (functional) -5.863 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the UO-31 Renal cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -5.862 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the ACHN Renal cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -5.844 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MDA-N Breast cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -5.834 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SK-MEL-5 Melanoma cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -5.787 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the NCI-H23 Non-Small Cell Lung cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -5.758 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SF-539 Central Nervous System cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -5.736 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HL-60(TB) Leukemia cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -5.644 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MALME-3M Melanoma cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -5.633 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SN12C Renal cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -5.476 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the DU-145 Prostate cell line. (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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