Detailed information for compound 1731204

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 512.641 | Formula: C35H32N2O2
  • H donors: 0 H acceptors: 2 LogP: 6.4 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 2
  • SMILES: CN1C[C@@H]([C@@]2([C@@]31C(=O)c1c4c3cccc4ccc1)Cc1c(C2=O)cccc1)c1ccc(cc1)N1CCCCC1
  • InChi: 1S/C35H32N2O2/c1-36-22-30(23-15-17-26(18-16-23)37-19-5-2-6-20-37)34(21-25-9-3-4-12-27(25)32(34)38)35(36)29-14-8-11-24-10-7-13-28(31(24)29)33(35)39/h3-4,7-18,30H,2,5-6,19-22H2,1H3/t30-,34+,35+/m1/s1
  • InChiKey: JHYNRHPRTDENDW-DCCHFUKUSA-N  


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Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0012 0.0013 0.0034
Echinococcus multilocularis casein kinase I alpha 0.001 0.0005 0.0022
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.001 0.0005 0.0022
Loa Loa (eye worm) major facilitator superfamily transporter 0.0074 0.0292 0.1257
Onchocerca volvulus Putative transporter 0.0074 0.0292 0.3402
Loa Loa (eye worm) Sars1 protein 0.0012 0.0013 0.0056
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.001 0.0005 0.0022
Echinococcus granulosus protein kinase shaggy 0.001 0.0005 0.0022
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0185 0.0787 1
Toxoplasma gondii sugar transporter ST2 0.0074 0.0292 0.0433
Plasmodium vivax sugar transporter, putative 0.0074 0.0292 0.0288
Loa Loa (eye worm) hypothetical protein 0.0074 0.0292 0.1257
Echinococcus multilocularis serine:threonine protein kinase 0.001 0.0005 0.0022
Trypanosoma cruzi aspartyl-tRNA synthetase, putative 0.0018 0.0039 0.0439
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.001 0.0005 0.0022
Brugia malayi major facilitator superfamily protein 0.0074 0.0292 0.1239
Trichomonas vaginalis glucosylceramidase, putative 0.0199 0.085 0.3641
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0162 0.0684 0.2942
Onchocerca volvulus 0.0074 0.0292 0.3402
Echinococcus multilocularis expressed conserved protein 0.001 0.0005 0.0022
Loa Loa (eye worm) CMGC/CLK protein kinase 0.001 0.0005 0.0022
Schistosoma mansoni aspartyl-tRNA synthetase 0.0018 0.0039 0.0148
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0118 0.0488 0.7266
Echinococcus multilocularis dual specificity 0.001 0.0005 0.0022
Echinococcus multilocularis ribosomal protein S6 kinase delta 1 0.001 0.0005 0.0022
Trichomonas vaginalis conserved hypothetical protein 0.0074 0.0292 0.1239
Echinococcus granulosus aspartyl tRNA synthetase cytoplasmic 0.0018 0.0039 0.0169
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0012 0.0013 0.0055
Echinococcus multilocularis asparaginyl tRNA synthetase, cytoplasmic 0.0018 0.0039 0.0169
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.001 0.0005 0.0022
Trypanosoma cruzi Aminoacyl-tRNA editing domain containing protein, putative 0.0026 0.0077 0.0925
Plasmodium vivax histidine--tRNA ligase, putative 0.0018 0.004 0.0035
Echinococcus multilocularis synaptic vesicle 2 protein 0.0074 0.0292 0.1257
Onchocerca volvulus 0.0074 0.0292 0.3402
Echinococcus multilocularis wee1 protein kinase 0.001 0.0005 0.0022
Echinococcus granulosus solute carrier family 22 0.0074 0.0292 0.1257
Loa Loa (eye worm) AGC/PKA protein kinase 0.001 0.0005 0.0022
Loa Loa (eye worm) hypothetical protein 0.0158 0.0669 0.2879
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0162 0.0685 0.068
Loa Loa (eye worm) CK1 protein kinase 0.001 0.0005 0.0022
Mycobacterium ulcerans prolyl-tRNA synthetase 0.0056 0.021 0.4256
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0018 0.0039 0.0439
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0012 0.0013 0.0034
Loa Loa (eye worm) CK1/WORM6 protein kinase 0.001 0.0005 0.0022
Trypanosoma brucei asparaginyl-tRNA synthetase, putative 0.0018 0.0039 0.0439
Loa Loa (eye worm) ULK/ULK protein kinase 0.001 0.0005 0.0022
Leishmania major protein kinase, putative 0.0162 0.0684 0.8684
Loa Loa (eye worm) AGC/NDR protein kinase 0.001 0.0005 0.0022
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.001 0.0005 0.0022
Echinococcus granulosus Threonyl tRNA synthetase C 0.003 0.0093 0.0399
Loa Loa (eye worm) CMGC/CDK/CRK7 protein kinase 0.001 0.0005 0.0022
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0018 0.0041 0.0177
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.001 0.0005 0.0022
Echinococcus multilocularis agc family protein kinase 0.001 0.0005 0.0022
Trichomonas vaginalis glucose transporter, putative 0.0074 0.0292 0.1239
Trichomonas vaginalis replication factor A 1, rfa1, putative 0.0015 0.0025 0.0086
Echinococcus granulosus serine:threonine protein kinase 17A 0.001 0.0005 0.0022
Echinococcus multilocularis calcium:calmodulin dependent protein kinase 0.001 0.0005 0.0022
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.001 0.0005 0.0022
Loa Loa (eye worm) CAMK/DAPK/DAPK protein kinase 0.001 0.0005 0.0022
Trypanosoma cruzi aspartyl-tRNA synthetase, putative 0.0018 0.0039 0.0439
Mycobacterium tuberculosis Conserved hypothetical protein 0.0026 0.0077 0.1795
Brugia malayi latrophilin 2 splice variant baaae 0.0074 0.0293 0.1241
Leishmania major lysyl-tRNA synthetase, putative 0.0118 0.0488 0.6173
Brugia malayi lysyl-tRNA synthetase 0.0118 0.0488 0.2081
Trichomonas vaginalis sugar transporter, putative 0.0074 0.0292 0.1239
Chlamydia trachomatis histidine--tRNA ligase 0.0018 0.004 0.0719
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0012 0.0013 0.0034
Echinococcus multilocularis dual specificity 0.001 0.0005 0.0022
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0018 0.0041 0.0204
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0077 0.0312
Echinococcus granulosus serine threonine protein kinase sik 0.001 0.0005 0.0022
Trypanosoma cruzi aspartyl-tRNA synthetase, putative 0.0015 0.0025 0.0254
Loa Loa (eye worm) hypothetical protein 0.001 0.0005 0.0022
Schistosoma mansoni sugar transporter 0.0074 0.0292 0.1239
Echinococcus granulosus serine/threonine-protein kinase greatwall 0.001 0.0005 0.0022
Loa Loa (eye worm) CMGC/CDK/CDK4 protein kinase 0.001 0.0005 0.0022
Toxoplasma gondii aspartate-tRNA ligase 0.0018 0.0039 0.0052
Loa Loa (eye worm) serine/threonine protein kinase 0.001 0.0005 0.0022
Trypanosoma brucei aspartyl-tRNA synthetase, putative 0.0018 0.0039 0.0439
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0043 0.0153 0.0148
Trypanosoma brucei glucose transporter, putative 0.0164 0.0693 0.8802
Brugia malayi RNA binding protein 0.0062 0.0238 0.1005
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0238 0.1005
Entamoeba histolytica asparaginyl-tRNA synthetase, putative 0.0018 0.0039 0.0193
Trypanosoma cruzi glucose transporter, putative 0.0074 0.0292 0.3675
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0055
Loa Loa (eye worm) hypothetical protein 0.0074 0.0292 0.1257
Echinococcus granulosus cpg binding protein 0.0031 0.0097 0.0418
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0012 0.0013 0.0034
Toxoplasma gondii exonuclease III APE 0.0018 0.0041 0.0055
Loa Loa (eye worm) sugar transporter 0.0074 0.0292 0.1257
Echinococcus granulosus TGF beta receptor type 1 0.001 0.0005 0.0022
Echinococcus multilocularis Threonyl tRNA synthetase, C 0.003 0.0093 0.0399
Echinococcus granulosus cyclin dependent kinase 9 0.001 0.0005 0.0022
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.001 0.0005 0.0022
Echinococcus multilocularis Cell division cycle 2 protein kinase 0.001 0.0005 0.0022
Echinococcus multilocularis homeodomain interacting protein kinase 3 0.001 0.0005 0.0022
Loa Loa (eye worm) NEK/NEK6 protein kinase 0.001 0.0005 0.0022
Loa Loa (eye worm) WNK protein kinase 0.001 0.0005 0.0022
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.001 0.0005 0.0022
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.001 0.0005 0.0022
Mycobacterium leprae PROBABLE DNA POLYMERASE III (ALPHA CHAIN) DNAE1 (DNA NUCLEOTIDYLTRANSFERASE) 0.0015 0.0025 0.0299
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0162 0.0684 0.2927
Loa Loa (eye worm) hypothetical protein 0.001 0.0005 0.0022
Trichomonas vaginalis sugar transporter, putative 0.0074 0.0292 0.1239
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0528 0.2325 1
Loa Loa (eye worm) acetyltransferase 0.0146 0.0616 0.2648
Echinococcus multilocularis serine:threonine protein kinase ULK3 0.001 0.0005 0.0022
Echinococcus multilocularis dual specificity 0.001 0.0005 0.0022
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.001 0.0005 0.0022
Onchocerca volvulus 0.0074 0.0292 0.3402
Trypanosoma cruzi hypothetical protein, conserved 0.0026 0.0077 0.0925
Plasmodium vivax lysine--tRNA ligase, putative 0.0118 0.0488 0.0483
Trichomonas vaginalis sugar transporter, putative 0.0074 0.0292 0.1239
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.001 0.0005 0.0022
Schistosoma mansoni hypothetical protein 0.0528 0.2325 1
Echinococcus granulosus cyclin dependent kinase 0.001 0.0005 0.0022
Echinococcus multilocularis protein KINase family member (kin 1) 0.001 0.0005 0.0022
Loa Loa (eye worm) AUR protein kinase 0.001 0.0005 0.0022
Loa Loa (eye worm) CK1/TTBKL protein kinase 0.001 0.0005 0.0022
Loa Loa (eye worm) CAMK/PKD protein kinase 0.001 0.0005 0.0022
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0162 0.0685 0.1024
Loa Loa (eye worm) AGC protein kinase 0.001 0.0005 0.0022
Loa Loa (eye worm) CMGC/CDK/CDK8 protein kinase 0.001 0.0005 0.0022
Echinococcus multilocularis STE20:SPS1 proline alanine rich protein 0.001 0.0005 0.0022
Echinococcus multilocularis protein kinase 0.001 0.0005 0.0022
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.0074 0.0292 0.5953
Schistosoma mansoni protein kinase 0.0162 0.0684 0.2927
Trypanosoma brucei seryl-tRNA synthetase 0.0012 0.0013 0.0101
Echinococcus granulosus protein kinase C gamma type 0.001 0.0005 0.0022
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0162 0.0684 0.2942
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0044 0.0158 0.0679
Plasmodium vivax threonine--tRNA ligase, putative 0.003 0.0093 0.0088
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.001 0.0005 0.0022
Loa Loa (eye worm) steroid hormone receptor 0.0012 0.0013 0.0055
Echinococcus granulosus leucine rich repeat serine:threonine protein 0.001 0.0005 0.0022
Loa Loa (eye worm) CK1 protein kinase 0.001 0.0005 0.0022
Echinococcus multilocularis serine:threonine protein kinase 36 0.001 0.0005 0.0022
Loa Loa (eye worm) serine/threonine protein kinase 0.001 0.0005 0.0022
Echinococcus multilocularis cpg binding protein 0.0031 0.0097 0.0418
Trichomonas vaginalis sugar transporter, putative 0.0164 0.0693 0.2967
Toxoplasma gondii YbaK/proline-tRNA ligase associated domain-containing protein 0.0026 0.0077 0.0109
Echinococcus granulosus maternal embryonic leucine zipper kinase 0.001 0.0005 0.0022
Loa Loa (eye worm) AGC/AKT protein kinase 0.001 0.0005 0.0022
Echinococcus multilocularis TGF beta receptor type 1 0.001 0.0005 0.0022
Echinococcus granulosus solute carrier family 22 0.0074 0.0292 0.1257
Loa Loa (eye worm) CK1/WORM6 protein kinase 0.001 0.0005 0.0022
Treponema pallidum asparaginyl-tRNA synthetase 0.0018 0.0039 0.1338
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.001 0.0005 0.0022
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0162 0.0685 0.1024
Trypanosoma brucei glucose transporter, putative 0.0164 0.0693 0.8802
Leishmania major replication factor A, 51kDa subunit, putative 0.0015 0.0025 0.0254
Echinococcus granulosus STE20:SPS1 proline alanine rich protein 0.001 0.0005 0.0022
Echinococcus granulosus serine threonine protein kinase nrc 0.001 0.0005 0.0022
Echinococcus multilocularis cyclin dependent kinase 16 0.001 0.0005 0.0022
Schistosoma mansoni protein kinase 0.0162 0.0684 0.2927
Onchocerca volvulus Protein ultraspiracle homolog 0.0012 0.0013 0.0093
Echinococcus multilocularis serine:threonine protein kinase N2 0.001 0.0005 0.0022
Wolbachia endosymbiont of Brugia malayi histidyl-tRNA synthetase 0.0018 0.004 0.0958
Loa Loa (eye worm) hypothetical protein 0.0074 0.0292 0.1257
Trichomonas vaginalis sugar transporter, putative 0.0074 0.0292 0.1239
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0034 0.0114 0.049
Trichomonas vaginalis sugar transport protein, putative 0.0074 0.0292 0.1239
Echinococcus multilocularis serine:threonine protein kinase receptor R3 0.001 0.0005 0.0022
Entamoeba histolytica acetyltransferase, GNAT family 0.0039 0.0137 0.0739
Loa Loa (eye worm) TKL/LRRK protein kinase 0.001 0.0005 0.0022
Loa Loa (eye worm) CK1/VRK protein kinase 0.001 0.0005 0.0022
Echinococcus granulosus dual specificity 0.001 0.0005 0.0022
Brugia malayi Asparaginyl-tRNA synthetase, cytoplasmic 0.0018 0.0039 0.0148
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.001 0.0005 0.0022
Loa Loa (eye worm) hypothetical protein 0.001 0.0005 0.0022
Schistosoma mansoni thyroid hormone receptor 0.0012 0.0013 0.0034
Mycobacterium ulcerans glycyl-tRNA synthetase 0.003 0.0093 0.182
Treponema pallidum aspartyl-tRNA synthetase 0.0018 0.0039 0.1338
Plasmodium vivax CDK-related protein kinase 6, putative 0.2239 1 1
Echinococcus granulosus cGMP dependent protein kinase 1 0.001 0.0005 0.0022
Schistosoma mansoni glucose transport protein 0.0528 0.2325 1
Echinococcus multilocularis cGMP dependent protein kinase 1 0.001 0.0005 0.0022
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0074 0.0292 0.1239
Loa Loa (eye worm) CK1/TTBKL protein kinase 0.001 0.0005 0.0022
Mycobacterium ulcerans integral membrane transport protein 0.0074 0.0292 0.5953
Echinococcus multilocularis Protein kinase C, brain isozyme 0.001 0.0005 0.0022
Toxoplasma gondii calcium-dependent protein kinase CDPK1 0.001 0.0005 0.0001
Echinococcus granulosus dual specificity 0.001 0.0005 0.0022
Loa Loa (eye worm) TKL/MLK/MLK protein kinase 0.001 0.0005 0.0022
Loa Loa (eye worm) STE/STE20/FRAY protein kinase 0.001 0.0005 0.0022
Trypanosoma cruzi replication Factor A 28 kDa subunit, putative 0.0015 0.0025 0.0254
Echinococcus granulosus Seryl tRNA Synthetase 0.0012 0.0013 0.0056
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.001 0.0005 0.0022
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.001 0.0005 0.0022
Loa Loa (eye worm) serine/threonine protein kinase 0.001 0.0005 0.0022
Loa Loa (eye worm) hypothetical protein 0.0034 0.0114 0.049
Schistosoma mansoni aspartyl-tRNA synthetase 0.0018 0.0039 0.0148
Echinococcus granulosus serine:threonine protein kinase 3 0.001 0.0005 0.0022
Echinococcus granulosus casein kinase I alpha 0.001 0.0005 0.0022
Onchocerca volvulus 0.0012 0.0013 0.0093
Trichomonas vaginalis sugar transporter, putative 0.0074 0.0292 0.1239
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0055
Brugia malayi Calcitonin receptor-like protein seb-1 0.0109 0.0447 0.1906
Echinococcus multilocularis ecdysone induced protein 78C 0.0012 0.0013 0.0055
Echinococcus multilocularis rho associated protein kinase 0.001 0.0005 0.0022
Schistosoma mansoni hypothetical protein 0.0023 0.0062 0.0247
Echinococcus granulosus serine:threonine protein kinase tousled 0.001 0.0005 0.0022
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.001 0.0005 0.0022
Leishmania major protein kinase, putative 0.001 0.0005 0.0005
Echinococcus granulosus TBC domain containing protein kinase 0.001 0.0005 0.0022
Echinococcus multilocularis cyclin dependent kinase 19 0.001 0.0005 0.0022
Giardia lamblia Sugar-proton symporter 0.0074 0.0292 0.1614
Echinococcus granulosus serine:threonine protein kinase N2 0.001 0.0005 0.0022
Onchocerca volvulus 0.0074 0.0292 0.3402
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.001 0.0005 0.0022
Schistosoma mansoni prolyl-tRNA synthetase 0.0012 0.0013 0.0034
Trichomonas vaginalis sugar transporter, putative 0.0164 0.0693 0.2967
Trypanosoma brucei CAMK/CAMKL family protein kinase, putative 0.001 0.0005 0.0005
Mycobacterium leprae Probable lysyl-tRNA synthase LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.01 0.0408 0.6068
Loa Loa (eye worm) STE/STE11/MEKK4 protein kinase 0.001 0.0005 0.0022
Schistosoma mansoni ap endonuclease 0.0018 0.0041 0.0156
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.001 0.0005 0.0022
Echinococcus multilocularis casein kinase I delta 0.001 0.0005 0.0022
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0012 0.0013 0.0055
Brugia malayi probable proline-trna synthetase - fission yeast, putative 0.003 0.0093 0.0379
Loa Loa (eye worm) hypothetical protein 0.0109 0.0447 0.1923
Echinococcus granulosus dual specificity mitogen activated protein 0.001 0.0005 0.0022
Echinococcus granulosus casein kinase i 0.001 0.0005 0.0022
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.001 0.0005 0.0022
Loa Loa (eye worm) CAMK/PKD protein kinase 0.001 0.0005 0.0022
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0061 0.0235 0.0993
Loa Loa (eye worm) hypothetical protein 0.001 0.0005 0.0022
Onchocerca volvulus 0.0074 0.0292 0.3402
Brugia malayi hypothetical protein 0.0074 0.0292 0.1239
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0118 0.0488 1
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.001 0.0005 0.0022
Plasmodium vivax hexose transporter 0.0528 0.2325 0.2322
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0158 0.0669 0.2864
Echinococcus multilocularis agc family protein kinase 0.001 0.0005 0.0022
Plasmodium falciparum replication protein A1, large subunit 0.0015 0.0025 0.002
Mycobacterium tuberculosis Probable threonyl-tRNA synthetase ThrS (threonine-tRNA synthetase)(ThrRS) (threonine-tRNA ligase) 0.003 0.0093 0.2179
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0012 0.0013 0.0034
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.001 0.0005 0.0022
Onchocerca volvulus 0.0074 0.0292 0.3402
Schistosoma mansoni nuclear hormone receptor 0.0012 0.0013 0.0034
Echinococcus multilocularis AP2 associated protein kinase 1 0.001 0.0005 0.0022
Trypanosoma cruzi hypothetical protein, conserved 0.0015 0.0025 0.0254
Echinococcus granulosus glycyl tRNA synthetase 0.003 0.0093 0.0399
Echinococcus granulosus cyclin dependent kinase 10 0.001 0.0005 0.0022
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0043 0.0153 0.0222
Plasmodium vivax aspartate--tRNA ligase, putative 0.0018 0.0039 0.0034
Echinococcus granulosus twitchin 0.001 0.0005 0.0022
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.001 0.0005 0.0022
Echinococcus multilocularis protein kinase c epsilon type 0.001 0.0005 0.0022
Echinococcus granulosus CDC7 cell division cycle 7 0.001 0.0005 0.0022
Loa Loa (eye worm) serine/threonine protein kinase 0.001 0.0005 0.0022
Schistosoma mansoni histidyl-tRNA synthetase 0.0018 0.004 0.015
Loa Loa (eye worm) CMGC/MAPK protein kinase 0.001 0.0005 0.0022
Loa Loa (eye worm) serine/threonine protein kinase 0.001 0.0005 0.0022
Plasmodium falciparum histone acetyltransferase GCN5 0.0039 0.0137 0.0132
Echinococcus granulosus phosphorylase kinase gamma subunit 0.001 0.0005 0.0022
Trypanosoma brucei glucose transporter 2A 0.0164 0.0693 0.8802
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.001 0.0005 0.0022
Echinococcus granulosus AP2 associated protein kinase 1 0.001 0.0005 0.0022
Echinococcus multilocularis scy1 protein 2 0.001 0.0005 0.0022
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0012 0.0013 0.0055
Echinococcus granulosus ecdysone induced protein 78C 0.0012 0.0013 0.0055
Leishmania major glycyl tRNA synthetase, putative 0.0018 0.004 0.0444
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.001 0.0005 0.0022
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0012 0.0013 0.0055
Toxoplasma gondii glycyl-tRNA synthetase 0.003 0.0093 0.0132
Chlamydia trachomatis aspartate--tRNA(Asp/Asn) ligase 0.0018 0.0039 0.0712
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0103 0.0423 0.18
Echinococcus granulosus Sugar transporter ERD6 protein 0.0074 0.0292 0.1257
Wolbachia endosymbiont of Brugia malayi prolyl-tRNA synthetase 0.003 0.0093 0.286
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0109 0.0447 0.1906
Loa Loa (eye worm) hypothetical protein 0.0118 0.0488 0.2098
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0012 0.0013 0.0034
Loa Loa (eye worm) hypothetical protein 0.0074 0.0292 0.1257
Schistosoma mansoni hypothetical protein 0.0362 0.1584 0.6804
Plasmodium falciparum histidine--tRNA ligase, putative 0.0018 0.004 0.0035
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.001 0.0005 0.0022
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0162 0.0684 0.2942
Echinococcus granulosus casein kinase I alpha 0.001 0.0005 0.0022
Echinococcus multilocularis mitogen activated protein kinase 14 0.001 0.0005 0.0022
Loa Loa (eye worm) STE/STE7 protein kinase 0.001 0.0005 0.0022
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.001 0.0005 0.0022
Toxoplasma gondii tRNA ligase class II core domain (G, H, P, S and T) domain-containing protein 0.0012 0.0013 0.0012
Echinococcus multilocularis geminin 0.0362 0.1584 0.6811
Loa Loa (eye worm) hypothetical protein 0.001 0.0005 0.0022
Brugia malayi exodeoxyribonuclease III family protein 0.0018 0.0041 0.0156
Brugia malayi TAR-binding protein 0.0062 0.0238 0.1005
Echinococcus multilocularis cyclin dependent kinase 17 0.001 0.0005 0.0022
Mycobacterium ulcerans aspartyl-tRNA synthetase 0.0018 0.0039 0.0712
Loa Loa (eye worm) CK1/WORM6 protein kinase 0.001 0.0005 0.0022
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0158 0.0669 0.2864
Echinococcus multilocularis beta adrenergic receptor kinase 0.001 0.0005 0.0022
Echinococcus multilocularis cyclin dependent kinase 0.001 0.0005 0.0022
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.0158 0.0659
Echinococcus granulosus tau tubulin kinase 1 0.001 0.0005 0.0022
Echinococcus granulosus serine:threonine protein kinase 0.001 0.0005 0.0022
Echinococcus multilocularis dual specificity mitogen activated protein 0.001 0.0005 0.0022
Echinococcus multilocularis vaccinia related kinase 1 0.001 0.0005 0.0022
Echinococcus multilocularis serine:threonine kinase SAD 1 0.001 0.0005 0.0022
Plasmodium falciparum calcium-dependent protein kinase 2 0.0162 0.0685 0.068
Echinococcus multilocularis serine threonine protein kinase 0.001 0.0005 0.0022
Leishmania major glucose transporter, lmgt1 0.0164 0.0693 0.8802
Loa Loa (eye worm) hypothetical protein 0.005 0.0184 0.079
Trichomonas vaginalis glucosylceramidase, putative 0.0303 0.1316 0.5652
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.001 0.0005 0.0022
Echinococcus multilocularis dual specificity mitogen activated protein 0.001 0.0005 0.0022
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.001 0.0005 0.0022
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0528 0.2325 1
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.001 0.0005 0.0022
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.001 0.0005 0.0022
Echinococcus multilocularis dual specificity protein kinase clk2 0.001 0.0005 0.0022
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0012 0.0013 0.0055
Trichomonas vaginalis glucosylceramidase, putative 0.0199 0.085 0.3641
Echinococcus multilocularis cyclin g associated kinase 0.001 0.0005 0.0022
Echinococcus multilocularis serine:threonine protein kinase MAK 0.001 0.0005 0.0022
Toxoplasma gondii anticodon binding domain-containing protein 0.0018 0.004 0.0052
Echinococcus multilocularis lysyl tRNA synthetase 0.0118 0.0488 0.2098
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0044 0.0158 0.0679
Entamoeba histolytica Rad52/22 family double-strand break repair protein, putative 0.0116 0.0479 0.2664
Trichomonas vaginalis sugar transporter, putative 0.0074 0.0292 0.1239
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0015 0.0025 0.002
Echinococcus multilocularis FTZ F1 alpha 0.0012 0.0013 0.0055
Loa Loa (eye worm) hypothetical protein 0.0074 0.0292 0.1257
Schistosoma mansoni threonyl-tRNA synthetase 0.0018 0.004 0.015
Mycobacterium tuberculosis Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter) 0.0074 0.0292 0.7128
Echinococcus granulosus homeodomain interacting protein kinase 3 0.001 0.0005 0.0022
Loa Loa (eye worm) CAMK/PIM protein kinase 0.001 0.0005 0.0022
Echinococcus multilocularis mitogen activated protein kinase 11 0.001 0.0005 0.0022
Trypanosoma cruzi histidyl-tRNA synthetase 0.0018 0.004 0.0444
Plasmodium falciparum proline--tRNA ligase 0.0185 0.0787 0.0782
Trichomonas vaginalis sugar transporter, putative 0.0074 0.0292 0.1239
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.001 0.0005 0.0022
Loa Loa (eye worm) STE/STE20/SLK protein kinase 0.001 0.0005 0.0022
Echinococcus multilocularis dual specificity mitogen activated protein 0.001 0.0005 0.0022
Loa Loa (eye worm) CK1/TTBKL protein kinase 0.001 0.0005 0.0022
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.001 0.0005 0.0022
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0238 0.1005
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0018 0.0041 0.0899
Onchocerca volvulus 0.0074 0.0292 0.3402
Echinococcus multilocularis serine:threonine protein kinase ULK4 0.001 0.0005 0.0022
Echinococcus granulosus cGMP dependent protein kinase 1 0.001 0.0005 0.0022
Trichomonas vaginalis sugar transporter, putative 0.0074 0.0292 0.1239
Onchocerca volvulus Bile acid receptor homolog 0.0012 0.0013 0.0093
Loa Loa (eye worm) CMGC/DYRK/PRP4 protein kinase 0.001 0.0005 0.0022
Schistosoma mansoni coup transcription factor 0.0012 0.0013 0.0034
Trypanosoma brucei threonyl-tRNA synthetase, putative 0.003 0.0093 0.1123
Echinococcus multilocularis twitchin 0.001 0.0005 0.0022
Schistosoma mansoni serine/threonine protein kinase 0.0162 0.0684 0.2927
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0018 0.0039 0.0439
Onchocerca volvulus 0.0074 0.0292 0.3402
Echinococcus granulosus beta-adrenergic receptor kinase 0.001 0.0005 0.0022
Echinococcus multilocularis serine:threonine protein kinase tousled 0.001 0.0005 0.0022
Echinococcus multilocularis agc family protein kinase 0.001 0.0005 0.0022
Echinococcus multilocularis Serine:threonine protein kinase PINK1 0.001 0.0005 0.0022
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.001 0.0005 0.0022
Loa Loa (eye worm) seryl-tRNA synthetase 0.0012 0.0013 0.0056
Giardia lamblia Asparaginyl-tRNA synthetase 0.0018 0.0039 0.0193
Trypanosoma brucei glucose transporter, putative 0.0164 0.0693 0.8802
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0528 0.2325 1
Mycobacterium ulcerans threonyl-tRNA synthetase 0.003 0.0093 0.182
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 7 0.001 0.0005 0.0022
Onchocerca volvulus 0.0074 0.0292 0.3402
Loa Loa (eye worm) CK1/WORM6 protein kinase 0.001 0.0005 0.0022
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.001 0.0005 0.0022
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.0041 0.0156
Echinococcus multilocularis protein kinase shaggy 0.001 0.0005 0.0022
Toxoplasma gondii sugar transporter ST1 0.0074 0.0292 0.0433
Echinococcus granulosus asparaginyl tRNA synthetase cytoplasmic 0.0018 0.0039 0.0169
Trypanosoma cruzi aspartyl-tRNA synthetase, putative 0.0015 0.0025 0.0254
Loa Loa (eye worm) TKL/IRAK protein kinase 0.001 0.0005 0.0022
Plasmodium vivax calcium-dependent protein kinase, putative 0.0162 0.0685 0.068
Trypanosoma brucei glucose transporter, putative 0.0164 0.0693 0.8802
Trichomonas vaginalis sugar transporter, putative 0.0074 0.0292 0.1239
Loa Loa (eye worm) RNA binding protein 0.0062 0.0238 0.1024
Echinococcus multilocularis cyclin dependent kinase 10 0.001 0.0005 0.0022
Trichomonas vaginalis sugar transporter, putative 0.0074 0.0292 0.1239
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0109 0.0447 0.1923
Loa Loa (eye worm) CMGC/CDK protein kinase 0.001 0.0005 0.0022
Echinococcus granulosus eukaryotic translation initiation factor 2 alpha 0.001 0.0005 0.0022
Loa Loa (eye worm) CMGC/GSK protein kinase 0.001 0.0005 0.0022
Echinococcus multilocularis myosin light chain kinase, smooth muscle 0.001 0.0005 0.0022
Echinococcus granulosus cyclin dependent kinase 17 0.001 0.0005 0.0022
Brugia malayi Sugar transporter family protein 0.0528 0.2325 1
Trichomonas vaginalis glucosylceramidase, putative 0.0209 0.0898 0.3848
Toxoplasma gondii histidyl-tRNA synthetase (HisRS), putative 0.0018 0.004 0.0052
Schistosoma mansoni hypothetical protein 0.0034 0.0114 0.047
Loa Loa (eye worm) hypothetical protein 0.0074 0.0292 0.1257
Echinococcus granulosus citron Rho interacting kinase 0.001 0.0005 0.0022
Echinococcus multilocularis tumor protein p63 0.0341 0.1489 0.6403
Loa Loa (eye worm) CAMK/CASK protein kinase 0.001 0.0005 0.0022
Trichomonas vaginalis replication factor A 1, rfa1, putative 0.0015 0.0025 0.0086
Echinococcus granulosus 5'partial|STE20 kinase adapter protein beta 0.001 0.0005 0.0022
Echinococcus multilocularis cyclin dependent kinase 6 0.001 0.0005 0.0022
Echinococcus multilocularis calcium dependent protein kinase 0.0152 0.0639 0.2749
Echinococcus multilocularis Serine:threonine protein kinase PRP4 0.001 0.0005 0.0022
Echinococcus granulosus seryl tRNA synthetase mitochondrial 0.0012 0.0013 0.0056
Trypanosoma brucei THT1 - hexose transporter, putative 0.0164 0.0693 0.8802
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.001 0.0005 0.0022
Echinococcus multilocularis histidyl tRNA synthetase 0.0018 0.004 0.0171
Plasmodium falciparum asparagine--tRNA ligase 0.0018 0.0039 0.0034
Leishmania major glucose transporter, lmgt2 0.0164 0.0693 0.8802
Trichomonas vaginalis sugar transporter, putative 0.0074 0.0292 0.1239
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0158 0.0669 0.3731
Entamoeba histolytica aspartyl-tRNA synthetase, putative 0.0018 0.0039 0.0193
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0018 0.0041 0.0751
Loa Loa (eye worm) hypothetical protein 0.001 0.0005 0.0022
Giardia lamblia Hexose transporter 0.0074 0.0292 0.1614
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.001 0.0005 0.0022
Trypanosoma cruzi hexose transporter, putative 0.0164 0.0693 0.8802
Brugia malayi photoreceptor-specific nuclear receptor 0.0012 0.0013 0.0034
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0303 0.1316 0.5661
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0012 0.0013 0.0055
Loa Loa (eye worm) protein kinase domain-containing protein 0.001 0.0005 0.0022
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0034 0.0114 0.049
Giardia lamblia Aspartyl-tRNA synthetase 0.0018 0.0039 0.0193
Schistosoma mansoni hypothetical protein 0.0034 0.0114 0.047
Loa Loa (eye worm) CK1/TTBKL protein kinase 0.001 0.0005 0.0022
Loa Loa (eye worm) 63kd antigen 0.0018 0.0039 0.0169
Trichomonas vaginalis sugar transporter, putative 0.0074 0.0292 0.1239
Echinococcus multilocularis calcium:calmodulin dependent protein kinase I 0.001 0.0005 0.0022
Leishmania major hypothetical protein, conserved 0.0074 0.0292 0.3675
Echinococcus multilocularis casein kinase I delta 0.001 0.0005 0.0022
Echinococcus granulosus serine:threonine protein kinase MARK2 0.001 0.0005 0.0022
Plasmodium falciparum aspartate--tRNA ligase 0.0018 0.0039 0.0034
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.001 0.0005 0.0022
Treponema pallidum prolyl-tRNA synthetase 0.0056 0.021 1
Entamoeba histolytica seryl-tRNA synthetase, putative 0.0012 0.0013 0.0045
Loa Loa (eye worm) AUR protein kinase 0.001 0.0005 0.0022
Brugia malayi RNA recognition motif domain containing protein 0.0062 0.0238 0.1005
Loa Loa (eye worm) TAR-binding protein 0.0062 0.0238 0.1024
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0118 0.0488 0.2081
Chlamydia trachomatis proline--tRNA ligase 0.0056 0.021 0.4256
Echinococcus multilocularis cyclin dependent kinase 1 0.001 0.0005 0.0022
Trichomonas vaginalis glucose transporter, putative 0.0164 0.0693 0.2967
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.001 0.0005 0.0022
Echinococcus granulosus histone acetyltransferase KAT2B 0.0043 0.0153 0.0657
Schistosoma mansoni hypothetical protein 0.0362 0.1584 0.6804
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.001 0.0005 0.0022
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.001 0.0005 0.0022
Trichomonas vaginalis sugar transporter, putative 0.0074 0.0292 0.1239
Entamoeba histolytica protein kinase, putative 0.0162 0.0684 0.3813
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0018 0.0041 0.1013
Giardia lamblia DNA repair protein RAD52 0.0407 0.1786 1
Echinococcus granulosus protein KINase family member kin 1 0.001 0.0005 0.0022
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.001 0.0005 0.0022
Mycobacterium ulcerans seryl-tRNA synthetase 0.0012 0.0013 0.0164
Brugia malayi Cam kinase protein 1 0.0162 0.0684 0.2927
Toxoplasma gondii threonyl-tRNA synthetase family protein 0.003 0.0093 0.0132
Echinococcus granulosus serine/threonine-protein kinase greatwall 0.001 0.0005 0.0022
Echinococcus granulosus serine:threonine protein kinase MAK 0.001 0.0005 0.0022
Echinococcus multilocularis thyroid hormone receptor alpha 0.0012 0.0013 0.0055
Echinococcus granulosus serine:threonine protein kinase N2 0.001 0.0005 0.0022
Loa Loa (eye worm) hypothetical protein 0.0074 0.0292 0.1257
Echinococcus granulosus solute carrier family 22 0.0074 0.0292 0.1257
Echinococcus granulosus serine:threonine protein kinase PLK1 0.001 0.0005 0.0022
Loa Loa (eye worm) CAMK protein kinase 0.001 0.0005 0.0022
Echinococcus granulosus serine:threonine protein kinase 12 B 0.001 0.0005 0.0022
Brugia malayi Nuclear hormone receptor-like 1 0.0012 0.0013 0.0034
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.001 0.0005 0.0022
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.001 0.0005 0.0022
Trichomonas vaginalis sugar transporter, putative 0.0074 0.0292 0.1239
Trichomonas vaginalis myo-inositol transporter, putative 0.0074 0.0292 0.1239
Echinococcus granulosus serine:threonine protein kinase MARK2 0.001 0.0005 0.0022
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.001 0.0005 0.0022
Echinococcus granulosus dual specificity 0.001 0.0005 0.0022
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0185 0.0787 1
Loa Loa (eye worm) hypothetical protein 0.001 0.0005 0.0022
Loa Loa (eye worm) STE/STE11/MEKK2 protein kinase 0.001 0.0005 0.0022
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.001 0.0005 0.0022
Loa Loa (eye worm) CMGC/GSK protein kinase 0.001 0.0005 0.0022
Schistosoma mansoni aspartyl-tRNA synthetase 0.0018 0.0039 0.0148
Echinococcus granulosus protein kinase c iota type 0.001 0.0005 0.0022
Echinococcus granulosus prolyl tRNA synthetase mitochondrial 0.0012 0.0013 0.0056
Echinococcus granulosus serine:threonine protein kinase SIK3 0.001 0.0005 0.0022
Plasmodium falciparum calcium-dependent protein kinase 1 0.0162 0.0685 0.068
Trichomonas vaginalis sugar transporter, putative 0.0074 0.0292 0.1239
Brugia malayi glycyl-tRNA synthetase 0.003 0.0093 0.0379
Loa Loa (eye worm) bifunctional aminoacyl-tRNA synthetase 0.0065 0.0251 0.108
Onchocerca volvulus 0.0074 0.0292 0.3402
Loa Loa (eye worm) CK1/WORM6 protein kinase 0.001 0.0005 0.0022
Loa Loa (eye worm) NAK/BIKE protein kinase 0.001 0.0005 0.0022
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.009 0.0386
Loa Loa (eye worm) CMGC/RCK/MAK protein kinase 0.001 0.0005 0.0022
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.001 0.0005 0.0022
Loa Loa (eye worm) IRE protein kinase 0.001 0.0005 0.0022
Loa Loa (eye worm) hypothetical protein 0.001 0.0005 0.0022
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.001 0.0005 0.0022
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0034 0.0114 0.049
Echinococcus multilocularis citron Rho interacting kinase 0.001 0.0005 0.0022
Brugia malayi Aspartyl-tRNA synthetase 0.0018 0.0039 0.0148
Loa Loa (eye worm) STE/STE20/YSK protein kinase 0.001 0.0005 0.0022
Trypanosoma brucei Replication factor A protein 1 0.0015 0.0025 0.0254
Echinococcus multilocularis Sugar transporter ERD6 protein 0.0074 0.0292 0.1257
Schistosoma mansoni threonyl-tRNA synthetase 0.0012 0.0013 0.0034
Brugia malayi hypothetical protein 0.0074 0.0292 0.1239
Plasmodium falciparum calcium-dependent protein kinase 4 0.0162 0.0685 0.068
Echinococcus granulosus cyclin dependent kinase 9 0.001 0.0005 0.0022
Trypanosoma brucei glucose transporter, putative 0.0164 0.0693 0.8802
Echinococcus granulosus ribosomal protein S6 kinase delta 1 0.001 0.0005 0.0022
Loa Loa (eye worm) CAMK/CAMKL/LKB protein kinase 0.001 0.0005 0.0022
Echinococcus granulosus agc family protein kinase 0.001 0.0005 0.0022
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.001 0.0005 0.0022
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0012 0.0013 0.0034
Loa Loa (eye worm) CK1/TTBK protein kinase 0.001 0.0005 0.0022
Echinococcus multilocularis serine:threonine protein kinase greatwall 0.001 0.0005 0.0022
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.001 0.0005 0.0005
Loa Loa (eye worm) CAMK/CAMKL/SNRK protein kinase 0.001 0.0005 0.0022
Toxoplasma gondii seryl-tRNA synthetase, cytoplasmic, putative 0.0012 0.0013 0.0012
Echinococcus multilocularis microtubule associated serine:threonine protein 0.001 0.0005 0.0022
Leishmania major hypothetical protein, conserved 0.0026 0.0077 0.0925
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0162 0.0684 0.2942
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0162 0.0684 0.2942
Trichomonas vaginalis conserved hypothetical protein 0.0164 0.0693 0.2967
Trichomonas vaginalis threonyl-tRNA synthetase, putative 0.003 0.0093 0.0379
Onchocerca volvulus 0.0074 0.0292 0.3402
Loa Loa (eye worm) SCY1 protein kinase 0.001 0.0005 0.0022
Entamoeba histolytica hypothetical protein 0.0015 0.0025 0.0112
Leishmania major lysyl-tRNA synthetase, putative 0.0018 0.0039 0.0439
Echinococcus granulosus serine:threonine protein kinase 36 0.001 0.0005 0.0022
Loa Loa (eye worm) CK1/WORM6 protein kinase 0.001 0.0005 0.0022
Echinococcus multilocularis dual specificity 0.001 0.0005 0.0022
Echinococcus multilocularis serine:threonine protein kinase:endoribonuclease 0.001 0.0005 0.0022
Echinococcus granulosus eukaryotic translation initiation factor 2 alpha 0.001 0.0005 0.0022
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0012 0.0013 0.0093
Echinococcus granulosus Microtubule-associated serine/threonine-protein kinase 0.001 0.0005 0.0022
Trichomonas vaginalis glucosylceramidase, putative 0.0199 0.085 0.3641
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.001 0.0005 0.0022
Echinococcus multilocularis serine:threonine protein kinase SIK3 0.001 0.0005 0.0022
Loa Loa (eye worm) CK1 protein kinase 0.001 0.0005 0.0022
Loa Loa (eye worm) CK1/TTBKL protein kinase 0.001 0.0005 0.0022
Schistosoma mansoni hypothetical protein 0.0034 0.0114 0.047
Trypanosoma brucei glycyl-tRNA synthetase, putative 0.003 0.0093 0.1123
Toxoplasma gondii calcium-dependent protein kinase CDPK2 0.001 0.0005 0.0001
Toxoplasma gondii sugar transporter ST3 0.0074 0.0292 0.0433
Entamoeba histolytica protein kinase, putative 0.0162 0.0684 0.3813
Entamoeba histolytica DNA repair and recombination protein RAD52, putative 0.0407 0.1786 1
Echinococcus granulosus serine:threonine protein kinase PAK 1 0.001 0.0005 0.0022
Toxoplasma gondii calcium-dependent protein kinase CDPK9 0.001 0.0005 0.0001
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.001 0.0005 0.0022
Echinococcus multilocularis tar DNA binding protein 0.0062 0.0238 0.1024
Schistosoma mansoni lysyl-tRNA synthetase 0.0118 0.0488 0.2081
Echinococcus granulosus vaccinia related kinase 1 0.001 0.0005 0.0022
Echinococcus multilocularis General substrate transporter 0.0453 0.1993 0.857
Echinococcus multilocularis mitogen activated protein kinase 14 0.001 0.0005 0.0022
Toxoplasma gondii serine--tRNA ligase 0.0012 0.0013 0.0012
Trypanosoma cruzi sugar transporter, putative 0.0074 0.0292 0.3675
Onchocerca volvulus Putative replication factor A 73 kDa subunit 0.0015 0.0025 0.0235
Schistosoma mansoni lysyl-tRNA synthetase 0.0118 0.0488 0.2081
Echinococcus granulosus STE20 serine:threonine protein kinase 0.001 0.0005 0.0022
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0162 0.0684 0.2942
Plasmodium falciparum lysine--tRNA ligase 0.0118 0.0488 0.0483
Echinococcus granulosus rho-associated protein kinase 1 0.001 0.0005 0.0022
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.001 0.0005 0.0022
Mycobacterium leprae Probable threonyl-tRNA synthetase ThrS (threonine-tRNA synthetase) (ThrRS) (Threonine-tRNA ligase) 0.003 0.0093 0.1322
Loa Loa (eye worm) CMGC/MAPK/NMO protein kinase 0.001 0.0005 0.0022
Echinococcus granulosus Cell division cycle 2 protein kinase 0.001 0.0005 0.0022
Echinococcus multilocularis STE20 kinase adapter protein beta 0.001 0.0005 0.0022
Toxoplasma gondii replication factor-a protein 1 (rpa1) subfamily protein 0.0015 0.0025 0.003
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0238 0.1005
Echinococcus granulosus serine:threonine protein kinase 11 0.001 0.0005 0.0022
Echinococcus multilocularis wee1 protein kinase 0.001 0.0005 0.0022
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0055
Echinococcus granulosus agc family protein kinase 0.001 0.0005 0.0022
Echinococcus granulosus rho-associated protein kinase 0.001 0.0005 0.0022
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.01 0.0408 1
Echinococcus multilocularis dual specificity 0.001 0.0005 0.0022
Plasmodium falciparum proline--tRNA ligase, putative 0.0012 0.0013 0.0008
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0012 0.0013 0.0055
Treponema pallidum glycyl-tRNA synthetase 0.0018 0.004 0.1356
Mycobacterium tuberculosis Probable DNA polymerase III (alpha chain) DnaE2 (DNA nucleotidyltransferase) 0.0015 0.0025 0.0493
Trichomonas vaginalis glucosylceramidase, putative 0.0303 0.1316 0.5652
Echinococcus granulosus Protein kinase C brain isozyme 0.001 0.0005 0.0022
Trichomonas vaginalis sugar transporter, putative 0.0074 0.0292 0.1239
Toxoplasma gondii protein kinase, putative 0.1491 0.6643 1
Echinococcus multilocularis c Jun NH2 terminal kinase 0.001 0.0005 0.0022
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.001 0.0005 0.0022
Loa Loa (eye worm) TBCK protein kinase 0.001 0.0005 0.0022
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0528 0.2325 1
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.001 0.0005 0.0022
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.001 0.0005 0.0022
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0044 0.0158 0.0679
Echinococcus multilocularis mitogen activated protein kinase 15 0.001 0.0005 0.0022
Chlamydia trachomatis serine--tRNA ligase 0.0012 0.0013 0.0164
Echinococcus multilocularis dual specificity serine:threonine tyrosine 0.001 0.0005 0.0022
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0055
Echinococcus multilocularis nuclear receptor binding protein 0.001 0.0005 0.0022
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0012 0.0013 0.0034
Echinococcus multilocularis serine:threonine protein kinase ULK2 0.001 0.0005 0.0022
Trichomonas vaginalis glucosylceramidase, putative 0.0303 0.1316 0.5652
Echinococcus granulosus nuclear receptor binding protein 0.001 0.0005 0.0022
Echinococcus multilocularis serine:threonine protein kinase SIK1 0.001 0.0005 0.0022
Plasmodium falciparum calcium-dependent protein kinase 5 0.0162 0.0685 0.068
Echinococcus multilocularis casein kinase I gamma 0.001 0.0005 0.0022
Entamoeba histolytica glycyl-tRNA synthetase, putative 0.003 0.0093 0.0493
Echinococcus granulosus FTZ F1 alpha 0.0012 0.0013 0.0055
Echinococcus granulosus agc family protein kinase 0.001 0.0005 0.0022
Mycobacterium ulcerans sugar transporter 0.0074 0.0292 0.5953
Echinococcus multilocularis protein kinase, core 0.001 0.0005 0.0022
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.001 0.0005 0.0022
Loa Loa (eye worm) hypothetical protein 0.001 0.0005 0.0022
Loa Loa (eye worm) CK1/WORM6 protein kinase 0.001 0.0005 0.0022
Onchocerca volvulus 0.0074 0.0292 0.3402
Echinococcus multilocularis serine threonine protein kinase 0.001 0.0005 0.0022
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.001 0.0005 0.0022
Entamoeba histolytica histidyl-tRNA synthetase, putative 0.0018 0.004 0.0195
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.001 0.0005 0.0022
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.001 0.0005 0.0022
Echinococcus multilocularis aurora kinase A 0.001 0.0005 0.0022
Loa Loa (eye worm) hypothetical protein 0.0074 0.0292 0.1257
Trichomonas vaginalis conserved hypothetical protein 0.0074 0.0292 0.1239
Echinococcus granulosus TGF-beta receptor type-1 0.001 0.0005 0.0022
Trypanosoma cruzi threonyl-tRNA synthetase, putative 0.003 0.0093 0.1123
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.001 0.0005 0.0022
Loa Loa (eye worm) CAMK/PIM protein kinase 0.001 0.0005 0.0022
Plasmodium falciparum serine--tRNA ligase, putative 0.0012 0.0013 0.0008
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0162 0.0684 0.2942
Echinococcus granulosus asparaginyl tRNA synthetase, cytoplasmic 0.0018 0.0039 0.0169
Echinococcus granulosus serine:threonine protein kinase SIK1 0.001 0.0005 0.0022
Chlamydia trachomatis threonine--tRNA ligase 0.003 0.0093 0.182
Plasmodium vivax serine--tRNA ligase, putative 0.0012 0.0013 0.0008
Trichomonas vaginalis glucosylceramidase, putative 0.0303 0.1316 0.5652
Brugia malayi Sars1 protein 0.0012 0.0013 0.0034
Echinococcus granulosus 5'partial|3'partial|mitogen activated protein kinase kinase kinase 0.001 0.0005 0.0022
Echinococcus granulosus titin 0.001 0.0005 0.0022
Echinococcus granulosus synaptic vesicle 2 protein 0.0074 0.0292 0.1257
Echinococcus multilocularis serine:threonine protein kinase N2 0.001 0.0005 0.0022
Echinococcus granulosus protein kinase 0.001 0.0005 0.0022
Loa Loa (eye worm) hypothetical protein 0.0158 0.0669 0.2879
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0158 0.0669 0.2879
Loa Loa (eye worm) WEE protein kinase 0.001 0.0005 0.0022
Loa Loa (eye worm) AUR protein kinase 0.001 0.0005 0.0022
Trichomonas vaginalis sugar transporter, putative 0.0074 0.0292 0.1239
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.001 0.0005 0.0022
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0012 0.0013 0.0034
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0012 0.0013 0.0055
Echinococcus multilocularis cyclin dependent kinase 9 0.001 0.0005 0.0022
Loa Loa (eye worm) CK1/WORM6 protein kinase 0.001 0.0005 0.0022
Echinococcus granulosus wee1 protein kinase 0.001 0.0005 0.0022
Echinococcus granulosus glycogen synthase kinase 3 beta 0.001 0.0005 0.0022
Loa Loa (eye worm) glycyl-tRNA synthetase 0.003 0.0093 0.0399
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.001 0.0005 0.0022
Echinococcus multilocularis dual specificity mitogen activated protein 0.001 0.0005 0.0022
Loa Loa (eye worm) CK1/TTBK protein kinase 0.001 0.0005 0.0022
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0162 0.0684 0.2942
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0158 0.0669 0.2864
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0012 0.0013 0.0055
Leishmania major hypothetical protein, conserved 0.0026 0.0077 0.0925
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0012 0.0013 0.0034
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0162 0.0684 0.2942
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0146 0.0616 0.2632
Echinococcus multilocularis tau tubulin kinase 1 0.001 0.0005 0.0022
Echinococcus granulosus mitogen activated protein kinase 11 0.001 0.0005 0.0022
Echinococcus granulosus cyclin dependent kinase 1 0.001 0.0005 0.0022
Echinococcus multilocularis aspartyl tRNA synthetase, cytoplasmic 0.0018 0.0039 0.0169
Trichomonas vaginalis glucose transporter, putative 0.0164 0.0693 0.2967
Loa Loa (eye worm) CMGC/GSK protein kinase 0.001 0.0005 0.0022
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.001 0.0005 0.0022
Brugia malayi nuclear receptor NHR-88 0.0012 0.0013 0.0034
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0012 0.0013 0.0034
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.001 0.0005 0.0022
Echinococcus granulosus expressed protein 0.001 0.0005 0.0022
Onchocerca volvulus 0.0074 0.0292 0.3402
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.001 0.0005 0.0022
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0162 0.0685 0.068
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.001 0.0005 0.0022
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.001 0.0005 0.0022
Treponema pallidum threonyl-tRNA synthetase 0.003 0.0093 0.4047
Schistosoma mansoni RAR-like nuclear receptor 0.0012 0.0013 0.0034
Echinococcus multilocularis maternal embryonic leucine zipper kinase 0.001 0.0005 0.0022
Echinococcus granulosus peripheral plasma membrane protein CASK 0.001 0.0005 0.0022
Loa Loa (eye worm) TLK protein kinase 0.001 0.0005 0.0022
Trypanosoma brucei aspartyl-tRNA synthetase, putative 0.0018 0.0039 0.0439
Trypanosoma cruzi hypothetical protein, conserved 0.0026 0.0077 0.0925
Onchocerca volvulus 0.005 0.0184 0.2114
Echinococcus granulosus serine:threonine protein kinase WNK1 0.001 0.0005 0.0022
Echinococcus multilocularis cyclin dependent kinase 1 0.001 0.0005 0.0022
Trichomonas vaginalis glucosylceramidase, putative 0.0303 0.1316 0.5652
Loa Loa (eye worm) CK1/WORM6 protein kinase 0.001 0.0005 0.0022
Echinococcus granulosus myosin iiia 0.001 0.0005 0.0022
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.0158 0.0659
Toxoplasma gondii facilitative glucose transporter GT1 0.0528 0.2325 0.3495
Loa Loa (eye worm) sugar transporter 0.0528 0.2325 1
Trichomonas vaginalis glucosylceramidase, putative 0.0303 0.1316 0.5652
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.0041 0.0036
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0018 0.0041 0.0463
Loa Loa (eye worm) CMGC/CDK/CDK10 protein kinase 0.001 0.0005 0.0022
Echinococcus granulosus geminin 0.0362 0.1584 0.6811
Trichomonas vaginalis sugar transporter, putative 0.0074 0.0292 0.1239
Trichomonas vaginalis sugar transporter, putative 0.0074 0.0292 0.1239
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.001 0.0005 0.0022
Schistosoma mansoni hypothetical protein 0.0034 0.0114 0.047
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0012 0.0013 0.0034
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.001 0.0005 0.0022
Schistosoma mansoni glucose transport protein 0.0528 0.2325 1
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0185 0.0787 0.1178
Plasmodium vivax glycine--tRNA ligase, putative 0.003 0.0093 0.0088
Giardia lamblia Hypothetical protein 0.0015 0.0025 0.0112
Giardia lamblia Glycyl-tRNA synthetase 0.003 0.0093 0.0493
Loa Loa (eye worm) CAMK/PHK protein kinase 0.001 0.0005 0.0022
Brugia malayi CXXC zinc finger family protein 0.0029 0.009 0.0365
Loa Loa (eye worm) CAMK/CAMKL/NUAK protein kinase 0.001 0.0005 0.0022
Loa Loa (eye worm) TKL/STKR/TYPE2 protein kinase 0.001 0.0005 0.0022
Loa Loa (eye worm) hypothetical protein 0.003 0.0093 0.0399
Loa Loa (eye worm) NEK/NEK8 protein kinase 0.001 0.0005 0.0022
Brugia malayi nuclear hormone receptor 0.0012 0.0013 0.0034
Schistosoma mansoni seryl-tRNA synthetase 0.0012 0.0013 0.0034
Loa Loa (eye worm) hypothetical protein 0.0162 0.0684 0.2942
Echinococcus multilocularis rho associated protein kinase 1 0.001 0.0005 0.0022
Trypanosoma brucei THT1 - hexose transporter, putative 0.0164 0.0693 0.8802
Loa Loa (eye worm) replication factor A 73 kDa subunit 0.0015 0.0025 0.0107
Loa Loa (eye worm) CK1/DUAL protein kinase 0.001 0.0005 0.0022
Echinococcus multilocularis PAK box P21 Rho binding 0.001 0.0005 0.0022
Schistosoma mansoni cellular tumor antigen P53 0.005 0.0184 0.077
Loa Loa (eye worm) STE/STE7/MEK4 protein kinase 0.001 0.0005 0.0022
Trichomonas vaginalis replication factor A 1, rfa1, putative 0.0015 0.0025 0.0086
Trichomonas vaginalis sugar transporter, putative 0.0074 0.0292 0.1239
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.001 0.0005 0.0022
Loa Loa (eye worm) CAMK/TRBL protein kinase 0.001 0.0005 0.0022
Mycobacterium leprae conserved hypothetical protein 0.0026 0.0077 0.1089
Trypanosoma cruzi hexose transporter, putative 0.0089 0.0361 0.4549
Loa Loa (eye worm) CK1/WORM6 protein kinase 0.001 0.0005 0.0022
Entamoeba histolytica seryl-tRNA synthetase, putative 0.0012 0.0013 0.0045
Loa Loa (eye worm) hypothetical protein 0.001 0.0005 0.0022
Brugia malayi threonyl-tRNA synthetase, cytoplasmic 0.003 0.0093 0.0379
Trichomonas vaginalis conserved hypothetical protein 0.0528 0.2325 1
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0528 0.2325 1
Echinococcus multilocularis solute carrier family 22 0.0074 0.0292 0.1257
Trichomonas vaginalis seryl-tRNA synthetase, putative 0.0012 0.0013 0.0034
Schistosoma mansoni cpg binding protein 0.0029 0.009 0.0365
Schistosoma mansoni glycyl-tRNA synthetase 0.003 0.0093 0.0379
Plasmodium vivax replication protein A1, large subunit, putative 0.0015 0.0025 0.002
Echinococcus multilocularis tau tubulin kinase 1 0.001 0.0005 0.0022
Trichomonas vaginalis bromodomain-containing protein, putative 0.0043 0.0153 0.0636
Echinococcus multilocularis solute carrier family 22 0.0074 0.0292 0.1257
Trypanosoma cruzi hexose transporter, putative 0.0074 0.0292 0.3675
Echinococcus multilocularis serine:threonine protein kinase NLK 0.001 0.0005 0.0022
Loa Loa (eye worm) CK1/TTBK protein kinase 0.001 0.0005 0.0022
Echinococcus multilocularis expressed protein 0.001 0.0005 0.0022
Trypanosoma cruzi Replication factor A protein 1 0.0015 0.0025 0.0254
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0012 0.0013 0.0055
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0012 0.0013 0.0055
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.001 0.0005 0.0022
Echinococcus multilocularis leucine rich repeat serine:threonine protein 0.001 0.0005 0.0022
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0158 0.0669 1
Loa Loa (eye worm) STE/STE20/STLK protein kinase 0.001 0.0005 0.0022
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.001 0.0005 0.0022
Echinococcus multilocularis serine:threonine protein kinase 3 0.001 0.0005 0.0022
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.01 0.0408 1
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.001 0.0005 0.0022
Echinococcus multilocularis solute carrier family 22 0.0074 0.0292 0.1257
Mycobacterium ulcerans hypothetical protein 0.0026 0.0077 0.1499
Trichomonas vaginalis sugar transporter, putative 0.0074 0.0292 0.1239
Echinococcus granulosus General substrate transporter 0.0453 0.1993 0.857
Schistosoma mansoni steroid hormone receptor ad4bp 0.0012 0.0013 0.0034
Echinococcus multilocularis mitogen activated protein kinase 11 0.001 0.0005 0.0022
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0034 0.0114 0.047
Echinococcus multilocularis agc family protein kinase 0.001 0.0005 0.0022
Echinococcus granulosus MAP kinase activated protein kinase 2 0.001 0.0005 0.0022
Trypanosoma brucei glucose transporter, putative 0.0164 0.0693 0.8802
Loa Loa (eye worm) VPS15 protein kinase 0.001 0.0005 0.0022
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.001 0.0005 0.0022
Echinococcus multilocularis mitogen activated protein kinase 0.001 0.0005 0.0022
Loa Loa (eye worm) aspartyl-tRNA synthetase 0.0018 0.0039 0.0169
Trichomonas vaginalis sugar transporter, putative 0.0074 0.0292 0.1239
Echinococcus granulosus serine:threonine kinase SAD 1 0.001 0.0005 0.0022
Leishmania major myo-inositol/proton symporter (MIT) 0.0074 0.0292 0.3675
Echinococcus granulosus tar DNA binding protein 0.0062 0.0238 0.1024
Loa Loa (eye worm) CMGC/CDK protein kinase 0.001 0.0005 0.0022
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0528 0.2325 1
Chlamydia trachomatis lysine--tRNA ligase 0.0118 0.0488 1
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0238 0.1005
Leishmania major asparaginyl-tRNA synthetase, putative 0.0018 0.0039 0.0439
Echinococcus multilocularis cGMP dependent protein kinase 1 0.001 0.0005 0.0022
Trichomonas vaginalis sugar transporter, putative 0.0074 0.0292 0.1239
Trichomonas vaginalis sugar transporter, putative 0.0074 0.0292 0.1239
Trypanosoma cruzi aspartyl-tRNA synthetase, putative 0.0018 0.0039 0.0439
Echinococcus granulosus histone acetyltransferase KAT2B 0.0142 0.0597 0.2569
Echinococcus granulosus serine:threonine protein kinase NLK 0.001 0.0005 0.0022
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.001 0.0005 0.0022
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.001 0.0005 0.0022
Echinococcus multilocularis cyclin dependent kinase 1 0.001 0.0005 0.0022
Echinococcus granulosus serine:threonine protein kinase Chk2 0.001 0.0005 0.0022
Schistosoma mansoni cpg binding protein 0.0031 0.0097 0.0397
Loa Loa (eye worm) CAMK/PIM protein kinase 0.001 0.0005 0.0022
Wolbachia endosymbiont of Brugia malayi major facilitator superfamily permease 0.0074 0.0292 1
Loa Loa (eye worm) hypothetical protein 0.0074 0.0292 0.1257
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.0041 0.0036
Loa Loa (eye worm) CMGC/GSK protein kinase 0.001 0.0005 0.0022
Loa Loa (eye worm) CK1 protein kinase 0.001 0.0005 0.0022
Schistosoma mansoni seryl-tRNA synthetase 0.0012 0.0013 0.0034
Leishmania major aspartyl-tRNA synthetase, putative 0.0018 0.0039 0.0439
Echinococcus multilocularis casein kinase i 0.001 0.0005 0.0022
Echinococcus granulosus dual specificity mitogen activated protein 0.001 0.0005 0.0022
Loa Loa (eye worm) AGC/YANK protein kinase 0.001 0.0005 0.0022
Plasmodium falciparum calcium-dependent protein kinase 3 0.0162 0.0685 0.068
Echinococcus multilocularis G protein coupled receptor kinase 6 0.001 0.0005 0.0022
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.001 0.0005 0.0022
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0012 0.0013 0.0034
Mycobacterium tuberculosis Probable conserved integral membrane transport protein 0.0074 0.0292 0.7128
Echinococcus granulosus Serine:threonine protein kinase PRP4 0.001 0.0005 0.0022
Echinococcus multilocularis serine:threonine protein kinase 17A 0.001 0.0005 0.0022
Echinococcus multilocularis dual specificity testis specific protein kinase 0.001 0.0005 0.0022
Loa Loa (eye worm) haspin protein kinase 0.001 0.0005 0.0022
Trichomonas vaginalis sugar transporter, putative 0.0074 0.0292 0.1239
Schistosoma mansoni retinoic acid receptor RXR 0.0012 0.0013 0.0034
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.001 0.0005 0.0022
Leishmania major glucose transporter/membrane transporter D2, putative 0.0164 0.0693 0.8802
Brugia malayi major facilitator superfamily protein 0.0074 0.0292 0.1239
Loa Loa (eye worm) IKK protein kinase 0.001 0.0005 0.0022
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0118 0.0488 0.6173
Echinococcus multilocularis peripheral plasma membrane protein CASK 0.001 0.0005 0.0022
Brugia malayi Major Facilitator Superfamily protein 0.0074 0.0292 0.1239
Loa Loa (eye worm) NAK/GAK protein kinase 0.001 0.0005 0.0022
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0012 0.0013 0.0055
Trichomonas vaginalis glucosylceramidase, putative 0.0199 0.085 0.3641
Loa Loa (eye worm) AGC/NDR protein kinase 0.001 0.0005 0.0022
Echinococcus multilocularis glycyl tRNA synthetase 0.003 0.0093 0.0399
Brugia malayi acetyltransferase, GNAT family protein 0.0146 0.0616 0.2632
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0018 0.0039 0.0439
Trichomonas vaginalis sugar transporter, putative 0.0074 0.0292 0.1239
Echinococcus granulosus c-Jun N-terminal kinases 0.001 0.0005 0.0022
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.001 0.0005 0.0022
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0853 0.3782 0.569
Echinococcus multilocularis dual specificity 0.001 0.0005 0.0022
Echinococcus multilocularis casein kinase I alpha 0.001 0.0005 0.0022
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0162 0.0684 0.8684
Echinococcus granulosus cyclin g associated kinase 0.001 0.0005 0.0022
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0012 0.0013 0.0034
Loa Loa (eye worm) CK1/TTBKL protein kinase 0.001 0.0005 0.0022
Loa Loa (eye worm) camk/dcamkl protein kinase 0.001 0.0005 0.0022
Loa Loa (eye worm) PEK/PEK protein kinase 0.001 0.0005 0.0022
Echinococcus multilocularis eukaryotic translation initiation factor 2 alpha 0.001 0.0005 0.0022
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.001 0.0005 0.0022
Echinococcus granulosus tyrosine protein kinase Lyn 0.001 0.0005 0.0022
Onchocerca volvulus 0.0074 0.0292 0.3402
Loa Loa (eye worm) threonyl-tRNA synthetase 0.003 0.0093 0.0399
Schistosoma mansoni sugar transporter 0.0074 0.0292 0.1239
Trypanosoma cruzi threonyl-tRNA synthetase, putative 0.003 0.0093 0.1123
Schistosoma mansoni hypothetical protein 0.0074 0.0293 0.1241
Leishmania major threonyl-tRNA synthetase, putative 0.003 0.0093 0.1123
Schistosoma mansoni aspartyl-tRNA synthetase 0.0015 0.0025 0.0086
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.001 0.0005 0.0022
Trypanosoma brucei Aminoacyl-tRNA editing domain containing protein, putative 0.0026 0.0077 0.0925
Echinococcus multilocularis calcium activated potassium channel 0.001 0.0005 0.0022
Loa Loa (eye worm) hypothetical protein 0.001 0.0005 0.0022
Echinococcus granulosus cyclin dependent kinase 16 0.001 0.0005 0.0022
Echinococcus granulosus cyclin dependent kinase 1 0.001 0.0005 0.0022
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0012 0.0013 0.0055
Echinococcus granulosus death associated protein kinase 1 0.001 0.0005 0.0022
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.001 0.0005 0.0022
Trypanosoma cruzi hexose transporter 0.0164 0.0693 0.8802
Echinococcus multilocularis cyclin dependent kinase 9 0.001 0.0005 0.0022
Trypanosoma cruzi glycyl-tRNA synthetase, putative 0.0018 0.004 0.0444
Loa Loa (eye worm) hypothetical protein 0.0129 0.0536 0.2307
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0012 0.0013 0.0034
Echinococcus multilocularis asparaginyl tRNA synthetase 0.0018 0.0039 0.0169
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0043 0.0153 0.0222
Schistosoma mansoni aspartyl-tRNA synthetase 0.0018 0.0039 0.0148
Loa Loa (eye worm) CAMK/CAMKL/NIM1 protein kinase 0.001 0.0005 0.0022
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0055
Echinococcus granulosus cyclin dependent kinase 19 0.001 0.0005 0.0022
Plasmodium falciparum serine--tRNA ligase, putative 0.0012 0.0013 0.0008
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0034 0.0114 0.049
Echinococcus granulosus mitogen activated protein kinase 14 0.001 0.0005 0.0022
Echinococcus multilocularis serine:threonine protein kinase 11 0.001 0.0005 0.0022
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.001 0.0005 0.0022
Giardia lamblia Histone acetyltransferase GCN5 0.0039 0.0137 0.0739
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.001 0.0005 0.0022
Loa Loa (eye worm) hypothetical protein 0.0074 0.0292 0.1257
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.0074 0.0292 0.5953
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0018 0.0041 0.0177
Echinococcus granulosus serine/threonine protein kinase 0.001 0.0005 0.0022
Trypanosoma brucei glucose transporter 1E 0.0164 0.0693 0.8802
Echinococcus granulosus calcium dependent protein kinase 0.0152 0.0639 0.2749
Echinococcus multilocularis replication protein A 70 kDa DNA binding 0.0015 0.0025 0.0107
Trichomonas vaginalis sugar transporter, putative 0.0074 0.0292 0.1239
Echinococcus multilocularis agc family protein kinase 0.001 0.0005 0.0022
Echinococcus granulosus dual specificity serine:threonine tyrosine 0.001 0.0005 0.0022
Trypanosoma cruzi hexose transporter, putative 0.0164 0.0693 0.8802
Echinococcus granulosus NDR protein kinase 0.001 0.0005 0.0022
Loa Loa (eye worm) STE/STE7/MEK3 protein kinase 0.001 0.0005 0.0022
Echinococcus multilocularis phosphorylase kinase gamma subunit 0.001 0.0005 0.0022
Plasmodium falciparum mitogen-activated protein kinase 2 0.0853 0.3782 0.3779
Schistosoma mansoni replication factor A 1 rfa1 0.0015 0.0025 0.0086
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.001 0.0005 0.0022
Loa Loa (eye worm) TKL/LISK/TESK protein kinase 0.001 0.0005 0.0022
Trichomonas vaginalis glucosylceramidase, putative 0.0199 0.085 0.3641
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.001 0.0005 0.0022
Trypanosoma brucei histidyl-tRNA synthetase 0.0018 0.004 0.0444
Loa Loa (eye worm) PEK/HRI protein kinase 0.001 0.0005 0.0022
Echinococcus granulosus myosin light chain kinase smooth muscle 0.001 0.0005 0.0022
Echinococcus multilocularis serine:threonine protein kinase NIM1 0.001 0.0005 0.0022
Echinococcus granulosus agc family protein kinase 0.001 0.0005 0.0022
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.001 0.0005 0.0022
Loa Loa (eye worm) latrophilin receptor protein 2 0.0034 0.0114 0.049
Loa Loa (eye worm) CK1 protein kinase 0.001 0.0005 0.0022
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0012 0.0013 0.0055
Loa Loa (eye worm) STE/STE7/MEK4 protein kinase 0.001 0.0005 0.0022
Loa Loa (eye worm) cmgc/cdk/pitslre protein kinase 0.001 0.0005 0.0022
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.001 0.0005 0.0022
Trichomonas vaginalis aspartyl/lysyl-tRNA synthetase, putative 0.0018 0.0039 0.0148
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0185 0.0787 1
Echinococcus multilocularis serine threonine protein kinase sik serine threonine protein kinase par 0.001 0.0005 0.0022
Loa Loa (eye worm) CK1/WORM6 protein kinase 0.001 0.0005 0.0022
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0303 0.1316 0.5652
Loa Loa (eye worm) G protein-coupled receptor kinase 1 0.001 0.0005 0.0022
Echinococcus granulosus serine:threonine protein kinase ULK4 0.001 0.0005 0.0022
Schistosoma mansoni thyroid hormone receptor 0.0012 0.0013 0.0034
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.001 0.0005 0.0022
Echinococcus multilocularis dual specificity mitogen activated protein 0.001 0.0005 0.0022
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0162 0.0684 0.2942
Echinococcus granulosus serine:threonine protein kinase TAO1 0.001 0.0005 0.0022
Trichomonas vaginalis sugar transporter, putative 0.0074 0.0292 0.1239
Brugia malayi Sugar transporter family protein 0.0074 0.0292 0.1239
Trichomonas vaginalis conserved hypothetical protein 0.0074 0.0292 0.1239
Echinococcus multilocularis serine:threonine protein kinase greatwall 0.001 0.0005 0.0022
Schistosoma mansoni cpg binding protein 0.0031 0.0097 0.0397
Loa Loa (eye worm) CMGC/CDK/CDK7 protein kinase 0.001 0.0005 0.0022
Echinococcus granulosus casein kinase ii subunit alpha 0.001 0.0005 0.0022
Echinococcus granulosus cyclin dependent kinase 7 0.001 0.0005 0.0022
Loa Loa (eye worm) major facilitator superfamily transporter 0.0074 0.0292 0.1257
Trypanosoma brucei glucose transporter, putative 0.0164 0.0693 0.8802
Brugia malayi ecdysteroid receptor 0.0012 0.0013 0.0034
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.001 0.0005 0.0022
Trichomonas vaginalis glucosylceramidase, putative 0.0199 0.085 0.3641
Trichomonas vaginalis sugar transporter, putative 0.0074 0.0292 0.1239
Echinococcus granulosus mitogen activated protein kinase 3 0.001 0.0005 0.0022
Echinococcus granulosus serine:threonine protein kinase NIM1 0.001 0.0005 0.0022
Echinococcus granulosus casein kinase I alpha 0.001 0.0005 0.0022
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0074 0.0292 0.0288
Loa Loa (eye worm) serine/threonine protein kinase 0.001 0.0005 0.0022
Echinococcus granulosus serine:threonine protein kinase ULK2 0.001 0.0005 0.0022
Echinococcus granulosus cyclin dependent kinase 1 0.001 0.0005 0.0022
Loa Loa (eye worm) hypothetical protein 0.0074 0.0293 0.126
Trichomonas vaginalis interferon-induced, double-stranded RNA-activated protein kinase, putative 0.0018 0.004 0.015
Loa Loa (eye worm) hypothetical protein 0.001 0.0005 0.0022
Echinococcus granulosus serine:threonine protein kinase:endoribonuclease 0.001 0.0005 0.0022
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0012 0.0013 0.0055
Echinococcus multilocularis casein kinase ii subunit alpha 0.001 0.0005 0.0022
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0012 0.0013 0.0055
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.001 0.0005 0.0022
Trichomonas vaginalis sugar transporter, putative 0.0074 0.0292 0.1239
Echinococcus granulosus dual specificity mitogen activated protein 0.001 0.0005 0.0022
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.001 0.0005 0.0022
Loa Loa (eye worm) CK1/WORM6 protein kinase 0.001 0.0005 0.0022
Echinococcus granulosus dual specificity 0.001 0.0005 0.0022
Schistosoma mansoni hypothetical protein 0.0015 0.0025 0.0086
Loa Loa (eye worm) CK1 protein kinase 0.001 0.0005 0.0022
Echinococcus multilocularis serine:threonine protein kinase WNK1 0.001 0.0005 0.0022
Plasmodium falciparum nucleic acid binding protein, putative 0.0015 0.0025 0.002
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.0074 0.0292 0.3675
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.001 0.0005 0.0022
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.001 0.0005 0.0022
Loa Loa (eye worm) CMGC/CDK/CDK9 protein kinase 0.001 0.0005 0.0022
Echinococcus multilocularis protein kinase c iota type 0.001 0.0005 0.0022
Trypanosoma cruzi Aminoacyl-tRNA editing domain containing protein, putative 0.0026 0.0077 0.0925
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0118 0.0488 1
Loa Loa (eye worm) CMGC/DYRK/HIPK protein kinase 0.001 0.0005 0.0022
Plasmodium vivax serine--tRNA ligase, putative 0.0012 0.0013 0.0008
Echinococcus granulosus G protein coupled receptor kinase 1 0.001 0.0005 0.0022
Echinococcus granulosus dual specificity mitogen activated protein 0.001 0.0005 0.0022
Schistosoma mansoni histidyl-tRNA synthetase 0.0018 0.004 0.015
Echinococcus granulosus tau tubulin kinase 1 0.001 0.0005 0.0022
Loa Loa (eye worm) SCY1 protein kinase 0.001 0.0005 0.0022
Trichomonas vaginalis conserved hypothetical protein 0.0074 0.0292 0.1239
Loa Loa (eye worm) histidyl-tRNA synthetase 0.0018 0.004 0.0171
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0012 0.0013 0.0034
Toxoplasma gondii transporter, major facilitator family protein 0.0074 0.0292 0.0433
Loa Loa (eye worm) hypothetical protein 0.0074 0.0292 0.1257
Echinococcus multilocularis serine threonine protein kinase 0.001 0.0005 0.0022
Toxoplasma gondii lysine-tRNA ligase 0.0118 0.0488 0.0727
Loa Loa (eye worm) NEK protein kinase 0.001 0.0005 0.0022
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.0158 0.0659
Echinococcus granulosus cell cycle related kinase 0.001 0.0005 0.0022
Schistosoma mansoni glucose transporter 0.0074 0.0292 0.1239
Trichomonas vaginalis glucosylceramidase, putative 0.0209 0.0898 0.3848
Plasmodium falciparum protein kinase 7 0.1491 0.6643 0.6642
Onchocerca volvulus Glucosylceramidase homolog 0.0199 0.085 1
Loa Loa (eye worm) NAK/MPSK protein kinase 0.001 0.0005 0.0022
Brugia malayi Sugar transporter family protein 0.0074 0.0292 0.1239
Trypanosoma brucei sugar transporter, putative 0.0074 0.0292 0.3675
Loa Loa (eye worm) hypothetical protein 0.001 0.0005 0.0022
Echinococcus granulosus dual specificity 0.001 0.0005 0.0022
Treponema pallidum exodeoxyribonuclease (exoA) 0.0018 0.0041 0.1433
Loa Loa (eye worm) CK1/WORM6 protein kinase 0.001 0.0005 0.0022
Loa Loa (eye worm) protein kinase domain-containing protein 0.001 0.0005 0.0022
Toxoplasma gondii histone lysine methyltransferase SET1 0.0059 0.0222 0.0327
Loa Loa (eye worm) STE/STE7/MEK7 protein kinase 0.001 0.0005 0.0022
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.001 0.0005 0.0005
Echinococcus granulosus dual specificity testis-specific protein kinase 0.001 0.0005 0.0022
Echinococcus granulosus Serine:threonine protein kinase PINK1 0.001 0.0005 0.0022
Schistosoma mansoni aspartyl-tRNA synthetase 0.0018 0.0039 0.0148
Schistosoma mansoni protein kinase 0.0162 0.0684 0.2927
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.001 0.0005 0.0022
Echinococcus multilocularis TBC domain containing protein kinase 0.001 0.0005 0.0022
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0018 0.0041 0.0463
Echinococcus granulosus Serine:threonine protein kinase PFTAIRE 1 0.001 0.0005 0.0022
Entamoeba histolytica hypothetical protein 0.0118 0.0488 0.2711
Echinococcus multilocularis myosin iiia 0.001 0.0005 0.0022
Trypanosoma cruzi seryl-tRNA synthetase 0.0012 0.0013 0.0101
Echinococcus granulosus [G-protein-coupledreceptor] kinase 0.001 0.0005 0.0022
Schistosoma mansoni aspartyl-tRNA synthetase 0.0018 0.0039 0.0148
Brugia malayi Major Facilitator Superfamily protein 0.0074 0.0292 0.1239
Echinococcus granulosus protein kinase core 0.001 0.0005 0.0022
Trypanosoma brucei THT1 - hexose transporter, putative 0.0164 0.0693 0.8802
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0018 0.0041 0.0177
Trichomonas vaginalis sugar transporter, putative 0.0074 0.0292 0.1239
Loa Loa (eye worm) CMGC/MAPK protein kinase 0.001 0.0005 0.0022
Loa Loa (eye worm) AGC/MAST/MAST protein kinase 0.001 0.0005 0.0022
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.001 0.0005 0.0022
Echinococcus granulosus lysyl tRNA synthetase 0.0118 0.0488 0.2098
Echinococcus granulosus cyclin dependent kinase 5 0.001 0.0005 0.0022
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0018 0.0041 0.0463
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0077 0.0312
Plasmodium falciparum hexose transporter 0.0528 0.2325 0.2322
Echinococcus multilocularis Seryl tRNA Synthetase 0.0012 0.0013 0.0056
Echinococcus granulosus serine threonine protein kinase 0.001 0.0005 0.0022
Loa Loa (eye worm) hypothetical protein 0.001 0.0005 0.0022
Trichomonas vaginalis glycyl-tRNA synthetase, putative 0.0012 0.0013 0.0034
Echinococcus granulosus dual specificity protein kinase clk2 0.001 0.0005 0.0022
Echinococcus multilocularis glycogen synthase kinase 3 0.001 0.0005 0.0022
Echinococcus multilocularis 0.001 0.0005 0.0022
Echinococcus granulosus wee1 protein kinase 0.001 0.0005 0.0022
Loa Loa (eye worm) TKL/MLK/LZK protein kinase 0.001 0.0005 0.0022
Toxoplasma gondii calcium-dependent protein kinase CDPK6 0.001 0.0005 0.0001
Echinococcus granulosus dual specificity 0.001 0.0005 0.0022
Loa Loa (eye worm) ULK protein kinase 0.001 0.0005 0.0022
Loa Loa (eye worm) hypothetical protein 0.0074 0.0292 0.1257
Trichomonas vaginalis sugar transporter, putative 0.0074 0.0292 0.1239
Loa Loa (eye worm) STE/STE7/MEK1 protein kinase 0.001 0.0005 0.0022
Echinococcus granulosus serine:threonine protein kinase ULK3 0.001 0.0005 0.0022
Onchocerca volvulus 0.0074 0.0292 0.3402
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0012 0.0013 0.0034
Loa Loa (eye worm) CMGC/CDK protein kinase 0.001 0.0005 0.0022
Loa Loa (eye worm) CAMK/CAMKL/PASK protein kinase 0.001 0.0005 0.0022
Trichomonas vaginalis CAMK family protein kinase 0.0162 0.0684 0.2927
Trichomonas vaginalis glucosylceramidase, putative 0.0199 0.085 0.3641
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0528 0.2325 1
Leishmania major glucose transporter, lmgt3 0.0164 0.0693 0.8802
Plasmodium vivax proline--tRNA ligase, putative 0.0012 0.0013 0.0008
Echinococcus multilocularis kinase protein 0.001 0.0005 0.0022
Loa Loa (eye worm) NRBP protein kinase 0.001 0.0005 0.0022
Loa Loa (eye worm) plk/plk-unclassified protein kinase 0.001 0.0005 0.0022
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0146 0.0616 0.2648
Leishmania major aspartyl-tRNA synthetase, putative 0.0018 0.0039 0.0439
Echinococcus granulosus GPCR family 2 0.0034 0.0114 0.049
Loa Loa (eye worm) CMGC/GSK protein kinase 0.001 0.0005 0.0022
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0012 0.0013 0.0034
Plasmodium vivax proline--tRNA ligase, putative 0.0185 0.0787 0.0782
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0238 0.1005
Trypanosoma cruzi asparaginyl-tRNA synthetase, putative 0.0018 0.0039 0.0439
Echinococcus granulosus serine:threonine protein kinase 0.001 0.0005 0.0022
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0162 0.0685 0.1024
Brugia malayi steroid hormone receptor 0.0012 0.0013 0.0034
Echinococcus multilocularis serine:threonine protein kinase Chk2 0.001 0.0005 0.0022
Echinococcus granulosus dual specificity mitogen activated protein 0.001 0.0005 0.0022
Wolbachia endosymbiont of Brugia malayi threonyl-tRNA synthetase 0.003 0.0093 0.286
Echinococcus granulosus mitogen activated protein kinase 0.001 0.0005 0.0022
Loa Loa (eye worm) CAMKK/META protein kinase 0.001 0.0005 0.0022
Schistosoma mansoni glucose transport protein 0.0528 0.2325 1
Echinococcus multilocularis cyclin dependent kinase 5 0.001 0.0005 0.0022
Schistosoma mansoni ap endonuclease 0.0018 0.0041 0.0156
Echinococcus granulosus mitogen activated protein kinase 15 0.001 0.0005 0.0022
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0162 0.0685 0.068
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.001 0.0005 0.0022
Echinococcus granulosus serine:threonine protein kinase 0.001 0.0005 0.0022
Leishmania major seryl-tRNA synthetase, putative 0.0012 0.0013 0.0101
Loa Loa (eye worm) hypothetical protein 0.001 0.0005 0.0022
Loa Loa (eye worm) BUB protein kinase 0.001 0.0005 0.0022
Schistosoma mansoni aspartyl-tRNA synthetase 0.0018 0.0039 0.0148
Entamoeba histolytica threonyl-tRNA synthetase, putative 0.003 0.0093 0.0493
Echinococcus multilocularis prolyl tRNA synthetase, mitochondrial 0.0012 0.0013 0.0056
Echinococcus granulosus casein kinase I delta 0.001 0.0005 0.0022
Echinococcus multilocularis dnaJ subfamily B 0.0413 0.1811 0.7787
Schistosoma mansoni sugar transporter 0.0074 0.0292 0.1239
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0018 0.0041 0.0204
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.001 0.0005 0.0022
Loa Loa (eye worm) CDC7 protein kinase 0.001 0.0005 0.0022
Echinococcus multilocularis CDC7 cell division cycle 7 0.001 0.0005 0.0022
Giardia lamblia Threonyl-tRNA synthetase 0.003 0.0093 0.0493
Loa Loa (eye worm) CAMK/PSK protein kinase 0.001 0.0005 0.0022
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0012 0.0013 0.0055
Trypanosoma brucei glucose transporter, putative 0.0164 0.0693 0.8802
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0185 0.0787 1
Onchocerca volvulus 0.0029 0.009 0.1003
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0012 0.0013 0.0034
Entamoeba histolytica hypothetical protein 0.0116 0.0479 0.2664
Echinococcus granulosus agc family protein kinase 0.001 0.0005 0.0022
Loa Loa (eye worm) hypothetical protein 0.001 0.0005 0.0022
Brugia malayi replication factor A 73 kDa subunit 0.0015 0.0025 0.0086
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0062 0.0238 0.1024
Echinococcus granulosus cyclin dependent kinase 6 0.001 0.0005 0.0022
Echinococcus multilocularis kinase protein 0.001 0.0005 0.0022
Giardia lamblia Lysyl-tRNA synthetase 0.0118 0.0488 0.2711
Giardia lamblia Seryl-tRNA synthetase 0.0012 0.0013 0.0045
Schistosoma mansoni sugar transporter 0.0074 0.0292 0.1239
Echinococcus multilocularis serine:threonine protein kinase 0.001 0.0005 0.0022
Loa Loa (eye worm) AGC/PKN protein kinase 0.001 0.0005 0.0022
Echinococcus multilocularis GPCR, family 2 0.0034 0.0114 0.049
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0044 0.0158 0.0679
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.001 0.0005 0.0022
Echinococcus granulosus aurora kinase A 0.001 0.0005 0.0022
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0853 0.3782 0.3779
Trichomonas vaginalis conserved hypothetical protein 0.0074 0.0292 0.1239
Loa Loa (eye worm) CAMK/DAPK/DAPK protein kinase 0.001 0.0005 0.0022
Schistosoma mansoni hypothetical protein 0.0413 0.1811 0.7783
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.001 0.0005 0.0022
Trypanosoma cruzi glycyl-tRNA synthetase, putative 0.0018 0.004 0.0444
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.001 0.0005 0.0022
Trichomonas vaginalis sugar transporter, putative 0.0074 0.0292 0.1239
Echinococcus multilocularis activin receptor type 0.001 0.0005 0.0022
Echinococcus granulosus dnaJ subfamily B 0.0413 0.1811 0.7787
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0158 0.0669 0.2879
Echinococcus multilocularis death associated protein kinase 1 0.001 0.0005 0.0022
Echinococcus multilocularis STE20 serine:threonine protein kinase 0.001 0.0005 0.0022
Trichomonas vaginalis seryl-tRNA synthetase, putative 0.0012 0.0013 0.0034
Trichomonas vaginalis glycyl-tRNA synthetase, putative 0.0018 0.004 0.015
Loa Loa (eye worm) CAMK protein kinase 0.001 0.0005 0.0022
Echinococcus granulosus serine threonine protein kinase 0.001 0.0005 0.0022
Trichomonas vaginalis conserved hypothetical protein 0.0164 0.0693 0.2967
Echinococcus granulosus protein kinase c epsilon type 0.001 0.0005 0.0022
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.001 0.0005 0.0022
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0077 0.0312
Brugia malayi Major Facilitator Superfamily protein 0.0074 0.0292 0.1239
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0158 0.0669 0.2864
Plasmodium falciparum asparagine--tRNA ligase 0.0018 0.0039 0.0034
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.001 0.0005 0.0022
Mycobacterium tuberculosis Probable DNA polymerase III (alpha chain) DnaE1 (DNA nucleotidyltransferase) 0.0015 0.0025 0.0493
Echinococcus multilocularis mitogen activated protein kinase 3 0.001 0.0005 0.0022
Loa Loa (eye worm) STE/STE11/ASK protein kinase 0.001 0.0005 0.0022
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0185 0.0787 1
Echinococcus granulosus replication protein A 70 kDa DNA binding 0.0015 0.0025 0.0107
Echinococcus multilocularis solute carrier family 22 0.0074 0.0292 0.1257
Onchocerca volvulus 0.0074 0.0292 0.3402
Echinococcus granulosus casein kinase I gamma 0.001 0.0005 0.0022
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0055
Loa Loa (eye worm) STE/STE7/MEK7 protein kinase 0.001 0.0005 0.0022
Wolbachia endosymbiont of Brugia malayi aspartyl-tRNA synthetase 0.0018 0.0039 0.0946
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0043 0.0153 0.0636
Trypanosoma cruzi hexose transporter, putative 0.0164 0.0693 0.8802
Echinococcus granulosus calcium:calmodulin dependent protein kinase I 0.001 0.0005 0.0022
Echinococcus multilocularis serine:threonine protein kinase 0.001 0.0005 0.0022
Loa Loa (eye worm) AGC/PKA protein kinase 0.001 0.0005 0.0022
Loa Loa (eye worm) hypothetical protein 0.0074 0.0292 0.1257
Mycobacterium ulcerans histidyl-tRNA synthetase 0.0018 0.004 0.0719
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.001 0.0005 0.0022
Plasmodium vivax asparagine--tRNA ligase, putative 0.0018 0.0039 0.0034
Echinococcus multilocularis serine:threonine protein kinase LATS2 0.001 0.0005 0.0022
Loa Loa (eye worm) AGC/PKG protein kinase 0.001 0.0005 0.0022
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0012 0.0013 0.0055
Brugia malayi Steroid receptor seven-up type 2 0.0012 0.0013 0.0034
Echinococcus granulosus calcium activated potassium channel 0.001 0.0005 0.0022
Echinococcus multilocularis cyclin dependent kinase 7 0.001 0.0005 0.0022
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0012 0.0013 0.0055
Plasmodium falciparum glycine--tRNA ligase 0.0018 0.004 0.0035
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0528 0.2325 1
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.001 0.0005 0.0022
Trichomonas vaginalis sugar transporter, putative 0.0074 0.0292 0.1239
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.001 0.0005 0.0022
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.001 0.0005 0.0022
Loa Loa (eye worm) hypothetical protein 0.001 0.0005 0.0022
Echinococcus multilocularis seryl tRNA synthetase, mitochondrial 0.0012 0.0013 0.0056
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.0041 0.0156
Echinococcus granulosus casein kinase I delta 0.001 0.0005 0.0022
Brugia malayi Latrophilin receptor protein 2 0.0034 0.0114 0.047
Echinococcus multilocularis casein kinase I alpha 0.001 0.0005 0.0022
Echinococcus granulosus serine:threonine protein kinase 0.001 0.0005 0.0022
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.001 0.0005 0.0022
Loa Loa (eye worm) hypothetical protein 0.0074 0.0292 0.1257
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0055
Loa Loa (eye worm) hypothetical protein 0.001 0.0005 0.0022
Echinococcus granulosus NDR protein kinase 0.001 0.0005 0.0022
Echinococcus granulosus titin 0.001 0.0005 0.0022
Brugia malayi seryl-tRNA synthetase, mitochondrial precursor, putative 0.0012 0.0013 0.0034
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0018 0.0041 0.0463
Leishmania major histidyl-tRNA synthetase, putative 0.0018 0.004 0.0444
Echinococcus multilocularis serine:threonine protein kinase 38 0.001 0.0005 0.0022
Brugia malayi hypothetical protein 0.0074 0.0292 0.1239
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.001 0.0005 0.0022
Loa Loa (eye worm) CMGC/SRPK protein kinase 0.001 0.0005 0.0022
Echinococcus granulosus scy1 protein 2 0.001 0.0005 0.0022
Echinococcus granulosus activin receptor type 0.001 0.0005 0.0022
Loa Loa (eye worm) hypothetical protein 0.0074 0.0292 0.1257
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.001 0.0005 0.0022
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0118 0.0488 0.6173
Trichomonas vaginalis sugar transporter, putative 0.0074 0.0292 0.1239
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0055
Plasmodium vivax asparagine--tRNA ligase, putative 0.0018 0.0039 0.0034
Schistosoma mansoni aspartyl-tRNA synthetase 0.0018 0.0039 0.0148
Loa Loa (eye worm) TTK protein kinase 0.001 0.0005 0.0022
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0012 0.0013 0.0055
Echinococcus multilocularis cyclin dependent kinase 11B 0.001 0.0005 0.0022
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.001 0.0005 0.0022
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0044 0.0158 0.0679
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.001 0.0005 0.0022
Trichomonas vaginalis sugar transporter, putative 0.0164 0.0693 0.2967
Echinococcus multilocularis cyclin dependent kinase 1 0.001 0.0005 0.0022
Echinococcus granulosus solute carrier family 22 0.0074 0.0292 0.1257
Leishmania major replication Factor A 28 kDa subunit, putative 0.0015 0.0025 0.0254
Echinococcus granulosus glycogen synthase kinase 3 0.001 0.0005 0.0022
Echinococcus granulosus cyclin dependent kinase 11B 0.001 0.0005 0.0022
Echinococcus multilocularis G protein coupled receptor kinase 1 0.001 0.0005 0.0022
Echinococcus granulosus 3'partial|mitogen activated protein kinase kinase kinase 0.001 0.0005 0.0022
Toxoplasma gondii OB-fold nucleic acid binding domain-containing protein 0.0015 0.0025 0.003
Echinococcus multilocularis Serine:threonine protein kinase PFTAIRE 1 0.001 0.0005 0.0022
Echinococcus granulosus cGMP dependent protein kinase 0.001 0.0005 0.0022
Echinococcus multilocularis eukaryotic translation initiation factor 2 alpha 0.001 0.0005 0.0022
Plasmodium falciparum threonine--tRNA ligase 0.003 0.0093 0.0088
Echinococcus multilocularis cell cycle related kinase 0.001 0.0005 0.0022
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0158 0.0669 0.2864
Echinococcus multilocularis serine:threonine protein kinase 0.001 0.0005 0.0022
Echinococcus multilocularis titin 0.001 0.0005 0.0022
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0044 0.0158 0.0659
Echinococcus granulosus histidyl tRNA synthetase 0.0018 0.004 0.0171
Echinococcus granulosus tumor protein p63 0.0341 0.1489 0.6403
Echinococcus multilocularis rac serine:threonine kinase 0.001 0.0005 0.0022
Echinococcus multilocularis asparaginyl tRNA synthetase, cytoplasmic 0.0018 0.0039 0.0169
Echinococcus granulosus protein kinase 0.001 0.0005 0.0022
Giardia lamblia Prolyl-tRNA synthetase 0.0158 0.0669 0.3731

Activities

Activity type Activity value Assay description Source Reference
EC50 (functional) = 17.75 uM Antitubercular activity against Mycobacterium tuberculosis H37Rv by BacTiter-Gl Microbial Cell Viability assay ChEMBL. 23352268
EC50 (functional) > 100 uM Antitubercular activity against Mycobacterium tuberculosis H37Rv by microdilution alamar Blue broth assay ChEMBL. 23352268
EC90 (functional) > 100 uM Antitubercular activity against Mycobacterium tuberculosis H37Rv by microdilution alamar Blue broth assay ChEMBL. 23352268
EC90 (functional) > 100 uM Antitubercular activity against Mycobacterium tuberculosis H37Rv by BacTiter-Gl Microbial Cell Viability assay ChEMBL. 23352268

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Mycobacterium tuberculosis 23352268

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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