Detailed information for compound 234311

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 472.617 | Formula: C27H40N2O5
  • H donors: 1 H acceptors: 3 LogP: 3.87 Rotable bonds: 12
    Rule of 5 violations (Lipinski): 1
  • SMILES: COC1CCCC(C1)C(=O)CN1CCCC1C(=O)NC(C(=O)OC(C)(C)C)Cc1ccccc1
  • InChi: 1S/C27H40N2O5/c1-27(2,3)34-26(32)22(16-19-10-6-5-7-11-19)28-25(31)23-14-9-15-29(23)18-24(30)20-12-8-13-21(17-20)33-4/h5-7,10-11,20-23H,8-9,12-18H2,1-4H3,(H,28,31)
  • InChiKey: UHFGEKKRWIBCPB-UHFFFAOYSA-N  


Substructure search Similarity search

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0013 0.0003 0.0009
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0055 0.0138 0.0738
Echinococcus granulosus mixed lineage leukemia protein mll 0.002 0.0026 0.0037
Loa Loa (eye worm) hypothetical protein 0.0019 0.0022 0.008
Schistosoma mansoni hypothetical protein 0.0477 0.1497 0.2137
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0046 0.0499
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0013 0.0003 0.0011
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0013 0.0003 0.0005
Brugia malayi Cytochrome P450 family protein 0.0074 0.0199 0.0716
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1212 0.3866 1
Echinococcus multilocularis 0.0014 0.0007 0.001
Loa Loa (eye worm) hypothetical protein 0.0023 0.0034 0.0122
Onchocerca volvulus 0.0058 0.0147 0.0464
Echinococcus multilocularis cpg binding protein 0.0066 0.0174 0.0249
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0006 0.0016
Echinococcus multilocularis musashi 0.0058 0.0147 0.021
Plasmodium falciparum glutathione reductase 0.0092 0.0258 0.8044
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0028 0.0049 0.0127
Onchocerca volvulus 0.0118 0.0341 0.1073
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0018 0.0019 0.0028
Plasmodium vivax DNA repair protein REV1, putative 0.0013 0.0002 0.0053
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0032 0.0063 0.0695
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0077 0.0209 0.0539
Loa Loa (eye worm) PXA domain-containing protein 0.0022 0.0033 0.0117
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0006 0.0016
Schistosoma mansoni jumonji/arid domain-containing protein 0.0072 0.0193 0.0276
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0041 0.0094 0.0503
Brugia malayi beta-NAC-like protein 0.0112 0.032 0.1148
Trypanosoma brucei DNA polymerase eta, putative 0.0041 0.0094 0.1029
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0055 0.0138 0.0738
Giardia lamblia DNA damage repair protein 0.0013 0.0002 0.0005
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0064 0.0167 0.5222
Onchocerca volvulus 0.0058 0.0147 0.0464
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0133 0.0388 0.2075
Echinococcus granulosus chromobox protein 1 0.0013 0.0003 0.0005
Entamoeba histolytica dual specificity protein phosphatase, putative 0.0568 0.1789 0.4629
Brugia malayi cytoplasmic intermediate filament protein 0.0031 0.0061 0.0218
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0022 0.0033 0.0047
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0042 0.0095 0.1035
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0237 0.0725 0.3882
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0022 0.0033 0.0084
Echinococcus granulosus regulator of G protein signaling 7 0.0022 0.0033 0.0047
Echinococcus multilocularis microtubule associated protein 2 0.2186 0.7005 1
Schistosoma mansoni regulator of G protein signaling 0.0022 0.0033 0.0047
Brugia malayi ImpB/MucB/SamB family protein 0.0041 0.0094 0.0337
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0013 0.0003 0.0012
Echinococcus multilocularis lysine specific demethylase 6a 0.0018 0.0019 0.0028
Schistosoma mansoni blooms syndrome DNA helicase 0.0037 0.0079 0.0113
Brugia malayi Thioredoxin reductase 0.0092 0.0258 0.0924
Treponema pallidum NADH oxidase 0.0032 0.0063 0.0084
Mycobacterium tuberculosis Probable reductase 0.021 0.0638 0.3415
Leishmania major DNA damage repair protein, putative 0.0013 0.0002 0.0022
Mycobacterium ulcerans DNA polymerase IV 0.0041 0.0094 0.0503
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0116 0.0334 0.1196
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0296 0.0913 1
Schistosoma mansoni aldehyde dehydrogenase 0.0133 0.0388 0.0554
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0055 0.0138 0.0738
Schistosoma mansoni regulator of G protein signaling 0.0022 0.0033 0.0047
Loa Loa (eye worm) hypothetical protein 0.0018 0.0019 0.007
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0127 0.037 0.037
Trypanosoma cruzi hypothetical protein, conserved 0.0013 0.0002 0.0022
Plasmodium vivax glutathione reductase, putative 0.0092 0.0258 0.6963
Leishmania major cytochrome p450-like protein 0.0055 0.0138 0.1509
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0028 0.0049 0.0127
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0069 0.0182 0.0259
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0055 0.0138 0.1509
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0296 0.0913 1
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0077 0.0209 0.2284
Brugia malayi PXA domain containing protein 0.0022 0.0033 0.0117
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0182 0.0546 0.1959
Schistosoma mansoni serine/threonine protein kinase 0.0105 0.03 0.0428
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0032 0.0063 0.0695
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0169 0.0505 0.0721
Trichomonas vaginalis set domain proteins, putative 0.0999 0.3178 0.822
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1212 0.3866 1
Schistosoma mansoni DNA helicase recq1 0.0019 0.0023 0.0032
Echinococcus multilocularis geminin 0.0167 0.0498 0.0711
Leishmania major basic transcription factor 3a, putative 0.0112 0.032 0.3505
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0055 0.0138 0.0738
Brugia malayi jmjC domain containing protein 0.0018 0.0019 0.007
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0077 0.0209 0.0748
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0064 0.0167 0.0432
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0003 0.0009
Plasmodium falciparum DNA repair protein REV1, putative 0.0013 0.0002 0.0062
Trichomonas vaginalis phosphofructokinase, putative 0.0237 0.0725 0.1876
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0296 0.0913 1
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.021 0.0638 0.3415
Trypanosoma brucei chrX additional, unordered contigs 0.0013 0.0002 0.0022
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0105 0.03 0.328
Trypanosoma brucei hypothetical protein, conserved 0.0024 0.0039 0.0432
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0133 0.0388 0.0554
Echinococcus granulosus cpg binding protein 0.0066 0.0174 0.0249
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0105 0.0298 0.0426
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0032 0.0063 0.0695
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0042 0.0095 0.1035
Trypanosoma cruzi DNA polymerase kappa, putative 0.0041 0.0094 0.1029
Plasmodium vivax histone acetyltransferase GCN5, putative 0.005 0.0121 0.3263
Giardia lamblia Nuclear LIM interactor-interacting factor 1 0.0014 0.0007 0.0019
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0055 0.0138 0.0738
Entamoeba histolytica hypothetical protein 0.0022 0.0033 0.0084
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0055 0.0138 0.0738
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0138 0.0404 0.0577
Echinococcus multilocularis chromobox protein 2 0.0013 0.0003 0.0005
Schistosoma mansoni ap endonuclease 0.0022 0.0031 0.0045
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0127 0.037 0.0528
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0064 0.0167 1
Entamoeba histolytica phosphofructokinase, putative 0.0237 0.0725 0.1876
Entamoeba histolytica NLI interacting factor-like phosphatase domain-containing protein 0.0014 0.0007 0.0019
Brugia malayi Associated with TFs and helicases family protein 0.0013 0.0003 0.0012
Trypanosoma brucei PAB1-binding protein , putative 0.0026 0.0046 0.0499
Giardia lamblia Fructose-bisphosphate aldolase 0.1212 0.3866 1
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0032 0.0063 0.0695
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0032 0.0063 0.0695
Onchocerca volvulus 0.0063 0.0163 0.0512
Onchocerca volvulus 0.0999 0.3178 1
Mycobacterium ulcerans aldehyde dehydrogenase 0.0133 0.0388 0.2075
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0013 0.0003 0.0009
Echinococcus granulosus lysine specific demethylase 5A 0.0072 0.0193 0.0276
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1212 0.3866 1
Loa Loa (eye worm) RecQ helicase 0.0047 0.0111 0.0397
Trypanosoma cruzi cytochrome P450, putative 0.0074 0.0199 0.2184
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0105 0.03 0.328
Plasmodium vivax JmjC domain containing protein 0.0018 0.0019 0.0527
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0055 0.0138 0.0738
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0024 0.0039 0.1067
Giardia lamblia Pyruvate kinase 0.0033 0.0066 0.017
Loa Loa (eye worm) hypothetical protein 0.0018 0.0019 0.007
Loa Loa (eye worm) jmjC domain-containing protein 0.0018 0.0019 0.007
Schistosoma mansoni pyruvate kinase 0.0033 0.0066 0.0094
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0013 0.0003 0.0107
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0003 0.0009
Echinococcus granulosus microtubule associated protein 2 0.2186 0.7005 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0094 0.1029
Loa Loa (eye worm) hypothetical protein 0.0019 0.0023 0.0081
Entamoeba histolytica phosphofructokinase, putative 0.0237 0.0725 0.1876
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0032 0.0063 0.034
Brugia malayi Pyruvate kinase, M2 isozyme 0.0033 0.0066 0.0236
Trichomonas vaginalis ap endonuclease, putative 0.0022 0.0031 0.0081
Mycobacterium tuberculosis Probable dehydrogenase 0.021 0.0638 0.3415
Schistosoma mansoni lamin 0.0058 0.0147 0.021
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0064 0.0167 0.5222
Trypanosoma brucei DNA polymerase IV, putative 0.0041 0.0094 0.1029
Trichomonas vaginalis phosphofructokinase, putative 0.0237 0.0725 0.1876
Entamoeba histolytica hypothetical protein 0.0013 0.0003 0.0009
Entamoeba histolytica recQ family helicase, putative 0.0025 0.0041 0.0105
Brugia malayi PXA domain containing protein 0.0022 0.0033 0.0117
Echinococcus granulosus chromobox protein 2 0.0013 0.0003 0.0005
Echinococcus multilocularis regulator of G protein signaling 0.0022 0.0033 0.0047
Echinococcus granulosus dna polymerase eta 0.0041 0.0094 0.0134
Echinococcus granulosus pyruvate kinase 0.0017 0.0015 0.0021
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0022 0.0033 0.0047
Brugia malayi ImpB/MucB/SamB family protein 0.0041 0.0094 0.0337
Echinococcus granulosus Regulator of G protein signaling 20 0.0022 0.0033 0.0047
Entamoeba histolytica phosphofructokinase, putative 0.0237 0.0725 0.1876
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0055 0.0138 0.0738
Mycobacterium ulcerans pyruvate kinase 0.0033 0.0066 0.0352
Loa Loa (eye worm) glutaminase 2 0.0319 0.0988 0.3542
Trypanosoma brucei DNA polymerase kappa, putative 0.0029 0.0053 0.0575
Trypanosoma brucei unspecified product 0.0029 0.0053 0.0575
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0033 0.0084
Trypanosoma brucei cytochrome P450, putative 0.0074 0.0199 0.2184
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0121 0.0351 0.0501
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0133 0.0388 0.4246
Schistosoma mansoni hypothetical protein 0.0167 0.0498 0.0711
Loa Loa (eye worm) hypothetical protein 0.0013 0.0002 0.0007
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0169 0.0505 0.0721
Schistosoma mansoni nuclear lim interactor-interacting factor (nli-interacting factor) (nli-if) 0.0014 0.0007 0.001
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0094 0.1029
Loa Loa (eye worm) intermediate filament protein 0.0058 0.0147 0.0529
Echinococcus multilocularis lamin dm0 0.0058 0.0147 0.021
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0051 0.0124 0.1356
Loa Loa (eye worm) jmjC domain-containing protein 0.0018 0.0019 0.007
Echinococcus multilocularis chromobox protein 1 0.0013 0.0003 0.0005
Entamoeba histolytica acetyltransferase, GNAT family 0.0046 0.0107 0.0278
Schistosoma mansoni chromobox protein 0.0013 0.0003 0.0005
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0041 0.0094 0.0243
Schistosoma mansoni ap endonuclease 0.0022 0.0031 0.0045
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0094 0.1029
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0055 0.0138 0.0738
Echinococcus granulosus Chromobox protein 3 0.0013 0.0003 0.0005
Mycobacterium leprae conserved hypothetical protein 0.0024 0.0039 0.0211
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0024 0.0039 0.0021
Loa Loa (eye worm) CYP4Cod1 0.0074 0.0199 0.0716
Loa Loa (eye worm) hypothetical protein 0.0022 0.0033 0.0117
Loa Loa (eye worm) POT family protein 0.008 0.0219 0.0787
Schistosoma mansoni regulator of G protein signaling 0.0022 0.0033 0.0047
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0023 0.0036 0.0128
Echinococcus multilocularis phd:f box containing protein 0.0018 0.0019 0.0028
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0024 0.0038 0.0054
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0022 0.0031 0.0975
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0025 0.0041 0.0447
Trichomonas vaginalis helicase, putative 0.0014 0.0006 0.0016
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0006 0.0016
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0055 0.0138 0.0738
Leishmania major pyruvate kinase 0.0033 0.0066 0.0721
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0024 0.0039 0.0039
Leishmania major DNA polymerase kappa, putative 0.0013 0.0002 0.0022
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0022 0.0033 0.0047
Giardia lamblia Histone acetyltransferase GCN5 0.0046 0.0107 0.0278
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0022 0.0031 0.0167
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.005 0.0121 0.0312
Mycobacterium ulcerans aldehyde dehydrogenase 0.0133 0.0388 0.2075
Schistosoma mansoni cytochrome P450 0.0055 0.0138 0.0197
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0592 0.1868 1
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0234 0.0714 0.3819
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0032 0.0063 0.034
Trichomonas vaginalis pps1 dual specificty phosphatase, putative 0.0568 0.1789 0.4629
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0105 0.03 0.328
Brugia malayi A-kinase anchor protein 10, precursor 0.0022 0.0033 0.0117
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0018 0.0019 0.0019
Loa Loa (eye worm) 6-phosphofructokinase 0.0237 0.0725 0.2602
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0028 0.0049 0.0127
Plasmodium falciparum histone acetyltransferase GCN5 0.0046 0.0107 0.3353
Trypanosoma cruzi DNA polymerase kappa, putative 0.0041 0.0094 0.1029
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0055 0.0138 0.0738
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.014 0.0412 0.4505
Echinococcus granulosus transcription factor Dp 1 0.0045 0.0104 0.0149
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0127 0.037 0.0528
Leishmania major cytochrome p450-like protein 0.0055 0.0138 0.1509
Loa Loa (eye worm) phosphofructokinase 0.0237 0.0725 0.2602
Toxoplasma gondii exonuclease III APE 0.0022 0.0031 0.0031
Plasmodium vivax pyruvate kinase, putative 0.0033 0.0066 0.1779
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0033 0.0084
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0003 0.0009
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0028 0.0049 0.0127
Schistosoma mansoni nuclear lim interactor-interacting factor (nli-interacting factor) (nli-if) 0.0014 0.0007 0.001
Echinococcus granulosus pyruvate kinase 0.0033 0.0066 0.0094
Mycobacterium ulcerans glutaminase 0.0319 0.0988 0.5285
Echinococcus multilocularis jumonji domain containing 1A 0.0018 0.0019 0.0028
Trypanosoma cruzi pyruvate kinase 2, putative 0.0033 0.0066 0.0721
Echinococcus granulosus jumonji domain containing 1A 0.0018 0.0019 0.0028
Plasmodium vivax hypothetical protein, conserved 0.0013 0.0003 0.0092
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0022 0.0033 0.0047
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1212 0.3866 1
Toxoplasma gondii NADPH-glutathione reductase 0.0032 0.0063 0.0063
Plasmodium falciparum thioredoxin reductase 0.0032 0.0063 0.1983
Leishmania major cytochrome p450-like protein 0.0074 0.0199 0.2184
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1212 0.3866 1
Plasmodium falciparum NLI interacting factor-like phosphatase, putative 0.0014 0.0007 0.0225
Brugia malayi M-phase phosphoprotein, mpp8 0.0118 0.0341 0.1223
Brugia malayi acetyltransferase, GNAT family protein 0.0169 0.0505 0.1812
Trypanosoma cruzi pyruvate kinase 2, putative 0.0033 0.0066 0.0721
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0032 0.0063 0.0695
Echinococcus multilocularis mitogen activated protein kinase 3 0.0105 0.03 0.0428
Trypanosoma brucei DNA polymerase IV, putative 0.0041 0.0094 0.1029
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0077 0.0209 0.0298
Brugia malayi Cytochrome P450 family protein 0.0055 0.0138 0.0494
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0031 0.0061 0.0061
Echinococcus granulosus L aminoadipate semialdehyde 0.0087 0.0241 0.0344
Echinococcus granulosus chromobox protein 1 0.0013 0.0003 0.0005
Trichomonas vaginalis chromobox protein, putative 0.0013 0.0003 0.0009
Entamoeba histolytica hypothetical protein 0.0112 0.032 0.0828
Brugia malayi Cytochrome P450 family protein 0.0074 0.0199 0.0716
Brugia malayi regulator of G-protein signaling rgs-7 0.0022 0.0033 0.0117
Echinococcus multilocularis Carboxy terminal domain RNA polymerase II 0.0014 0.0007 0.001
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0013 0.0003 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0033 0.0084
Echinococcus multilocularis pyruvate kinase 0.0033 0.0066 0.0094
Schistosoma mansoni regulator of G protein signaling 0.0022 0.0033 0.0047
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0032 0.0063 0.1716
Brugia malayi hypothetical protein 0.0017 0.0015 0.0056
Echinococcus multilocularis expressed protein 0.0435 0.1363 0.1946
Schistosoma mansoni regulator of G protein signaling 0.0022 0.0033 0.0047
Trichomonas vaginalis phosphofructokinase, putative 0.0064 0.0167 0.0432
Giardia lamblia DINP protein human, muc B family 0.0041 0.0094 0.0243
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0237 0.0725 0.7941
Trypanosoma brucei DNA damage repair protein, putative 0.0013 0.0002 0.0022
Loa Loa (eye worm) hypothetical protein 0.0013 0.0003 0.0012
Trichomonas vaginalis dullard protein, putative 0.0014 0.0007 0.0019
Loa Loa (eye worm) hypothetical protein 0.0027 0.0047 0.017
Trypanosoma cruzi DNA polymerase kappa, putative 0.0041 0.0094 0.1029
Entamoeba histolytica hypothetical protein 0.0024 0.0039 0.0102
Echinococcus granulosus regulator of G protein signaling 7 0.0022 0.0033 0.0047
Brugia malayi hypothetical protein 0.0022 0.0033 0.0117
Toxoplasma gondii NAC domain-containing protein 0.0112 0.032 0.032
Echinococcus granulosus dnaJ subfamily B 0.0477 0.1497 0.2137
Echinococcus granulosus Carboxy terminal domain RNA polymerase II 0.0014 0.0007 0.001
Schistosoma mansoni chromobox protein 0.0013 0.0003 0.0005
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.021 0.0638 0.3415
Loa Loa (eye worm) hypothetical protein 0.0057 0.0144 0.0517
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0055 0.0138 0.0738
Loa Loa (eye worm) hypothetical protein 0.0022 0.0033 0.0117
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0024 0.0039 0.1233
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0077 0.0209 0.0298
Leishmania major hypothetical protein, conserved 0.0026 0.0046 0.0499
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0028 0.0049 0.0127
Brugia malayi polk-prov protein 0.0013 0.0002 0.0007
Echinococcus granulosus Solute carrier family 22 5 0.1019 0.3244 0.4631
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0017 0.0015 0.0021
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0019 0.0023 0.0032
Trypanosoma brucei DNA polymerase kappa, putative 0.0013 0.0002 0.0022
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0006 0.0016
Echinococcus multilocularis axis inhibition protein axin 0.0022 0.0033 0.0047
Loa Loa (eye worm) CXXC zinc finger family protein 0.0063 0.0163 0.0583
Loa Loa (eye worm) hypothetical protein 0.0022 0.0033 0.0117
Toxoplasma gondii aldehyde dehydrogenase 0.0133 0.0388 0.0388
Toxoplasma gondii Dullard family phosphatase domain-containing protein 0.0014 0.0007 0.0007
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0182 0.0546 0.078
Brugia malayi chromobox protein homolog 3 0.0013 0.0003 0.0012
Trichomonas vaginalis CMGC family protein kinase 0.0105 0.03 0.0775
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0013 0.0003 0.0003
Echinococcus granulosus cytochrome P450 2K1 0.0055 0.0138 0.0197
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0022 0.0031 0.0044
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0017 0.0015 0.0021
Onchocerca volvulus 0.0118 0.0341 0.1073
Trichomonas vaginalis hypothetical protein 0.0013 0.0003 0.0009
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0017 0.0015 0.0021
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0055 0.0138 0.0738
Toxoplasma gondii histone lysine methyltransferase SET1 0.0128 0.0372 0.0372
Loa Loa (eye worm) histone methyltransferase 0.0024 0.0038 0.0136
Schistosoma mansoni jumonji domain containing protein 0.0069 0.0182 0.0259
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0019 0.0023 0.0704
Echinococcus multilocularis lysine specific demethylase 5A 0.0069 0.0182 0.0259
Echinococcus multilocularis thioredoxin glutathione reductase 0.0093 0.0259 0.037
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0055 0.0138 0.1509
Echinococcus multilocularis Ankyrin repeat domain containing protein 0.0105 0.0298 0.0426
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0022 0.0031 0.0844
Leishmania major trypanothione reductase 0.0092 0.0258 0.282
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0006 0.0016
Onchocerca volvulus Pyruvate kinase homolog 0.0033 0.0066 0.0207
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0105 0.03 0.328
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.017 0.0507 0.1818
Entamoeba histolytica transcription factor BTF3, putative 0.0112 0.032 0.0828
Schistosoma mansoni jumonji domain containing protein 0.0018 0.0019 0.0028
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0055 0.0138 0.0738
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0064 0.0167 0.0432
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0013 0.0003 0.0107
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0127 0.037 0.0528
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0055 0.0138 0.0738
Brugia malayi glutathione reductase 0.0092 0.0258 0.0924
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0094 0.1029
Brugia malayi Pre-SET motif family protein 0.0127 0.037 0.1327
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0006 0.0016
Brugia malayi 6-phosphofructokinase 0.0237 0.0725 0.2602
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0182 0.0546 0.2923
Trichomonas vaginalis nuclear lim interactor-interacting factor, putative 0.0014 0.0007 0.0019
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0592 0.1868 1
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0182 0.0546 0.078
Schistosoma mansoni chromobox protein 0.0013 0.0003 0.0005
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0055 0.0138 0.0738
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.021 0.0638 0.3415
Mycobacterium tuberculosis Putative ferredoxin reductase 0.021 0.0638 0.3415
Trypanosoma brucei hypothetical protein, conserved 0.0013 0.0002 0.0022
Schistosoma mansoni chromobox protein 0.0013 0.0003 0.0005
Echinococcus granulosus bloom syndrome protein 0.0047 0.0111 0.0158
Echinococcus granulosus lamin 0.0058 0.0147 0.021
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.1212 0.3866 1
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.005 0.0121 0.0121
Trichomonas vaginalis CMGC family protein kinase 0.0105 0.03 0.0775
Echinococcus multilocularis pyruvate kinase 0.0026 0.0044 0.0062
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0094 0.1029
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0024 0.0038 0.0054
Echinococcus granulosus lysine specific demethylase 6a 0.0018 0.0019 0.0028
Loa Loa (eye worm) hypothetical protein 0.0037 0.008 0.0288
Trichomonas vaginalis chromobox protein, putative 0.0013 0.0003 0.0009
Trichomonas vaginalis DNA polymerase eta, putative 0.0041 0.0094 0.0243
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0046 0.1425
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0055 0.0138 0.0738
Echinococcus multilocularis mitogen activated protein kinase 0.0105 0.03 0.0428
Schistosoma mansoni DNA polymerase IV / kappa 0.0013 0.0002 0.0003
Schistosoma mansoni 6-phosphofructokinase 0.0237 0.0725 0.1036
Echinococcus multilocularis transcription factor btf3 0.0112 0.032 0.0457
Trichomonas vaginalis phosphofructokinase, putative 0.0237 0.0725 0.1876
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0022 0.0031 0.4919
Leishmania major phosphopantetheinyl transferase-like protein 0.0024 0.0039 0.0432
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0105 0.0298 0.0426
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0032 0.0063 0.0063
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1212 0.3866 1
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0019 0.0023 0.0032
Echinococcus granulosus transcription factor btf3 0.0112 0.032 0.0457
Plasmodium vivax heterochromatin protein 1, putative 0.0013 0.0003 0.0092
Brugia malayi hypothetical protein 0.0026 0.0046 0.0164
Trichomonas vaginalis dullard protein, putative 0.0014 0.0007 0.0019
Entamoeba histolytica pyruvate kinase, putative 0.0023 0.0034 0.0088
Brugia malayi F/Y-rich N-terminus family protein 0.0024 0.0037 0.0133
Entamoeba histolytica hypothetical protein 0.0013 0.0003 0.0009
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0013 0.0003 0.0003
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0018 0.0019 0.0213
Echinococcus granulosus pyruvate kinase 0.0017 0.0015 0.0021
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0025 0.0041 0.0447
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0032 0.0063 0.1881
Trichomonas vaginalis phosphofructokinase, putative 0.0064 0.0167 0.0432
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1212 0.3866 1
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0182 0.0546 0.2923
Trichomonas vaginalis pyruvate kinase, putative 0.0033 0.0066 0.017
Echinococcus granulosus pyruvate kinase 0.0033 0.0066 0.0094
Loa Loa (eye worm) hypothetical protein 0.0022 0.0033 0.0117
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0041 0.0094 0.0134
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0003 0.0009
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0019 0.0023 0.0081
Loa Loa (eye worm) jmjC domain-containing protein 0.0072 0.0193 0.0692
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0006 0.0016
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0041 0.0092 0.2888
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0055 0.0138 0.0738
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0116 0.0334 0.0476
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0028 0.0049 0.0127
Loa Loa (eye worm) acetyltransferase 0.0169 0.0505 0.1812
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0019 0.0023 0.0032
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0023 0.0036 0.013
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0055 0.0138 0.1509
Loa Loa (eye worm) hypothetical protein 0.0014 0.0007 0.0026
Brugia malayi 6-phosphofructokinase 0.0237 0.0725 0.2602
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0003 0.0009
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0013 0.0003 0.0005
Echinococcus granulosus lamin dm0 0.0058 0.0147 0.021
Schistosoma mansoni phosphatidylserine receptor 0.0018 0.0019 0.0028
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0032 0.0063 0.0695
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.002 0.0026 0.0037
Loa Loa (eye worm) cytochrome P450 0.0055 0.0138 0.0494
Loa Loa (eye worm) glutathione reductase 0.0092 0.0258 0.0924
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.002 0.0026 0.0037
Schistosoma mansoni aldehyde dehydrogenase 0.0133 0.0388 0.0554
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0055 0.0138 0.0738
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0013 0.0003 0.0005
Loa Loa (eye worm) helicase 0.0013 0.0003 0.0012
Plasmodium vivax ataxin-2 like protein, putative 0.0026 0.0046 0.1233
Echinococcus granulosus regulator of G protein signaling 3 0.0022 0.0033 0.0047
Trichomonas vaginalis mercuric reductase, putative 0.0032 0.0063 0.0164
Toxoplasma gondii hypothetical protein 0.0048 0.0114 0.0114
Trichomonas vaginalis phosphofructokinase, putative 0.0064 0.0167 0.0432
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0116 0.0334 0.0476
Plasmodium vivax NLI interacting factor-like phosphatase, putative 0.0014 0.0007 0.0194
Trypanosoma brucei DNA polymerase kappa, putative 0.0029 0.0053 0.0575
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0019 0.0023 0.0081
Schistosoma mansoni cpg binding protein 0.0066 0.0174 0.0249
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0087 0.0241 0.0865
Brugia malayi Regulator of G protein signaling domain containing protein 0.0022 0.0033 0.0117
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0003 0.0009
Trichomonas vaginalis phosphofructokinase, putative 0.0064 0.0167 0.0432
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0116 0.0334 0.1196
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0046 0.0499
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0133 0.0388 0.0554
Trypanosoma brucei unspecified product 0.0041 0.0094 0.1029
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0033 0.0084
Trichomonas vaginalis nuclear lim interactor-interacting factor, putative 0.0014 0.0007 0.0019
Echinococcus multilocularis regulator of G protein signaling 7 0.0022 0.0033 0.0047
Echinococcus granulosus axis inhibition protein axin 0.0022 0.0033 0.0047
Brugia malayi Cytochrome P450 family protein 0.0077 0.021 0.0752
Echinococcus multilocularis regulator of G protein signaling 3 0.0022 0.0033 0.0047
Loa Loa (eye worm) cytochrome P450 family protein 0.0074 0.0199 0.0716
Brugia malayi MAP kinase sur-1 0.0105 0.03 0.1074
Leishmania major ATP-dependent phosphofructokinase 0.0237 0.0725 0.7941
Brugia malayi hypothetical protein 0.0118 0.0341 0.1223
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0024 0.0039 0.6216
Plasmodium falciparum thioredoxin reductase 0.0092 0.0258 0.8044
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0127 0.037 0.0528
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0041 0.0094 0.0134
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0094 0.1029
Mycobacterium tuberculosis Conserved hypothetical protein 0.0041 0.0094 0.0503
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0032 0.0063 0.1716
Trichomonas vaginalis chromobox protein, putative 0.0013 0.0003 0.0009
Loa Loa (eye worm) hypothetical protein 0.0027 0.0047 0.017
Brugia malayi Pre-SET motif family protein 0.0878 0.2788 1
Chlamydia trachomatis pyruvate kinase 0.0033 0.0066 0.2063
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0092 0.0258 0.1378
Echinococcus granulosus thioredoxin glutathione reductase 0.0093 0.0259 0.037
Loa Loa (eye worm) jmjC domain-containing protein 0.0018 0.0019 0.007
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0055 0.0138 0.0738
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0022 0.0031 0.0081
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0094 0.1029
Loa Loa (eye worm) hypothetical protein 0.0018 0.0019 0.007
Schistosoma mansoni DNA helicase recq5 0.0019 0.0023 0.0032
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0094 0.1029
Schistosoma mansoni serine/threonine protein kinase 0.0023 0.0036 0.0051
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0105 0.03 0.328
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.014 0.0412 0.4505
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0028 0.0049 0.0127
Loa Loa (eye worm) hypothetical protein 0.0087 0.0241 0.0865
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0032 0.0063 0.0695
Trypanosoma cruzi DNA damage repair protein, putative 0.0013 0.0002 0.0022
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0019 0.0023 0.0032
Loa Loa (eye worm) heterochromatin protein 1 0.0013 0.0003 0.0012
Trichomonas vaginalis dullard protein, putative 0.0014 0.0007 0.0019
Echinococcus granulosus histone acetyltransferase KAT2B 0.0164 0.049 0.0699
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0077 0.0209 0.0298
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0064 0.0167 0.0432
Schistosoma mansoni cpg binding protein 0.0066 0.0174 0.0249
Brugia malayi exodeoxyribonuclease III family protein 0.0022 0.0031 0.0112
Mycobacterium leprae putative cytochrome p450 0.0055 0.0138 0.0738
Schistosoma mansoni phd/f-box containing protein 0.0018 0.0019 0.0028
Trypanosoma brucei trypanothione reductase 0.0092 0.0258 0.282
Loa Loa (eye worm) pyruvate kinase 0.0033 0.0066 0.0236
Trichomonas vaginalis chromobox protein, putative 0.0013 0.0003 0.0009
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0105 0.03 0.03
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0592 0.1868 1
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0032 0.0063 0.0695
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0042 0.0095 0.1035
Trypanosoma brucei transcription factor BTF3, putative 0.0112 0.032 0.3505
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0032 0.0063 0.034
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0234 0.0714 0.3819
Toxoplasma gondii 6-phosphofructokinase 0.0064 0.0167 0.0167
Loa Loa (eye worm) hypothetical protein 0.0014 0.0007 0.0024
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0032 0.0062 0.1679
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0069 0.0182 0.0259
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0032 0.0063 0.0091
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0031 0.0061 0.0218
Leishmania major DNA polymerase eta, putative 0.0041 0.0094 0.1029
Echinococcus granulosus axis inhibition protein axin 0.0022 0.0033 0.0047
Echinococcus multilocularis Chromobox protein 3 0.0013 0.0003 0.0005
Brugia malayi Valyl-tRNA synthetase 0.0013 0.0003 0.0012
Trichomonas vaginalis DNA helicase recq, putative 0.0025 0.0041 0.0105
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0105 0.03 0.328
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0013 0.0003 0.0009
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0023 0.0036 0.013
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0022 0.0033 0.0047
Echinococcus granulosus phd:f box containing protein 0.0018 0.0019 0.0028
Trypanosoma brucei DNA polymerase kappa, putative 0.0029 0.0053 0.0575
Brugia malayi jmjC domain containing protein 0.0018 0.0019 0.007
Echinococcus multilocularis chromobox protein 1 0.0013 0.0003 0.0005
Mycobacterium ulcerans 6-phosphofructokinase 0.0237 0.0725 0.3882
Loa Loa (eye worm) CHromoDomain protein family member 0.0017 0.0015 0.0054
Echinococcus granulosus mitogen activated protein kinase 0.0105 0.03 0.0428
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0024 0.0039 0.0211
Trypanosoma brucei pyruvate kinase 1 0.0033 0.0066 0.0721
Echinococcus granulosus pyruvate kinase 0.0017 0.0015 0.0021
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0116 0.0334 0.0476
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0014 0.0004 0.0006
Onchocerca volvulus 0.014 0.0413 0.1299
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.0116 0.0334 0.0476
Schistosoma mansoni axis inhibition protein axin 0.0022 0.0033 0.0047
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0055 0.0138 0.0738
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0013 0.0003 0.0005
Trypanosoma brucei unspecified product 0.0029 0.0053 0.0575
Brugia malayi phosphofructokinase 0.0237 0.0725 0.2602
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0018 0.0019 0.0213
Echinococcus granulosus 6 phosphofructokinase 0.0237 0.0725 0.1036
Toxoplasma gondii thioredoxin reductase 0.0092 0.0258 0.0258
Trypanosoma brucei DNA damage repair protein, putative 0.0013 0.0002 0.0022
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0041 0.0094 0.1029
Plasmodium vivax pyruvate kinase 2, putative 0.0017 0.0015 0.0395
Echinococcus multilocularis Regulator of G protein signaling 20 0.0022 0.0033 0.0047
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0127 0.037 0.0528
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0033 0.0084
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0033 0.0084
Echinococcus multilocularis pyruvate kinase 0.0017 0.0015 0.0021
Trichomonas vaginalis CMGC family protein kinase 0.0105 0.03 0.0775
Schistosoma mansoni hypothetical protein 0.0055 0.0138 0.0197
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0024 0.0039 0.0039
Loa Loa (eye worm) hypothetical protein 0.0033 0.0066 0.0236
Trypanosoma brucei hypothetical protein, conserved 0.0013 0.0002 0.0022
Brugia malayi jmjC domain containing protein 0.0072 0.0193 0.0692
Echinococcus granulosus beta-adrenergic receptor kinase 0.0023 0.0036 0.0051
Echinococcus granulosus geminin 0.0167 0.0498 0.0711
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0023 0.0036 0.0128
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0023 0.0036 0.0128
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0055 0.0138 0.0738
Echinococcus multilocularis bloom syndrome protein 0.0047 0.0111 0.0158
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1212 0.3866 1
Echinococcus granulosus JmjC domain containing protein 4 0.0018 0.0019 0.0028
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0018 0.0019 0.0019
Schistosoma mansoni protein phosphatase 2C 0.0018 0.0019 0.0028
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0022 0.0031 0.0342
Plasmodium vivax thioredoxin reductase, putative 0.0092 0.0258 0.6963
Onchocerca volvulus 0.0087 0.0241 0.0759
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.021 0.0638 0.3415
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0028 0.0051 0.0072
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0055 0.0138 0.0738
Trichomonas vaginalis chromobox protein, putative 0.0013 0.0003 0.0009
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0032 0.0063 0.1983
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0041 0.0094 0.0337
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0032 0.0063 0.0695
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0055 0.0138 0.1509
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0032 0.0063 0.1983
Trypanosoma cruzi DNA polymerase eta, putative 0.0013 0.0002 0.0022
Echinococcus multilocularis pyruvate kinase 0.0017 0.0015 0.0021
Mycobacterium tuberculosis Conserved hypothetical protein 0.0156 0.0462 0.2475
Brugia malayi POT family protein 0.008 0.0219 0.0787
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0041 0.0094 0.0134
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0032 0.0063 0.0091
Loa Loa (eye worm) pyruvate kinase 0.0033 0.0066 0.0236
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0055 0.0138 0.0738
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.1212 0.3866 1
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0003 0.0009
Loa Loa (eye worm) 6-phosphofructokinase 0.0237 0.0725 0.2602
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0003 0.0009
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0046 0.1425
Brugia malayi Regulator of G protein signaling domain containing protein 0.0022 0.0033 0.0117
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0006 0.0016
Loa Loa (eye worm) ICD-1 protein 0.0112 0.032 0.1148
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0028 0.0049 0.0127
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0003 0.0009
Trichomonas vaginalis phosphofructokinase, putative 0.0237 0.0725 0.1876
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0077 0.0209 0.2284
Schistosoma mansoni microtubule-associated protein tau 0.2186 0.7005 1
Brugia malayi glutaminase DH11.1 0.0319 0.0988 0.3542
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0022 0.0031 0.0342
Brugia malayi Protein cec-1. 0.0013 0.0003 0.0012
Echinococcus granulosus intermediate filament protein 0.0058 0.0147 0.021
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0055 0.0138 0.0738
Schistosoma mansoni jumonji/arid domain-containing protein 0.0072 0.0193 0.0276
Schistosoma mansoni glutaminase 0.0319 0.0988 0.141
Brugia malayi Intermediate filament tail domain containing protein 0.0058 0.0147 0.0529
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0237 0.0725 0.7941
Brugia malayi intermediate filament protein 0.0058 0.0147 0.0529
Schistosoma mansoni hypothetical protein 0.0167 0.0498 0.0711
Entamoeba histolytica hypothetical protein 0.0022 0.0033 0.0084
Schistosoma mansoni DNA polymerase eta 0.0041 0.0094 0.0134
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0055 0.0138 0.0738
Plasmodium falciparum heterochromatin protein 1 0.0013 0.0003 0.0107
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0074 0.0199 0.1068
Brugia malayi Bloom's syndrome protein homolog 0.0047 0.0111 0.0397
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0022 0.0031 0.0045
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0032 0.0063 0.0695
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0028 0.0051 0.0072
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0013 0.0003 0.0009
Trypanosoma cruzi trypanothione reductase, putative 0.0032 0.0063 0.0695
Loa Loa (eye worm) pyruvate kinase-PB 0.0023 0.0034 0.0122
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0024 0.0039 0.0211
Plasmodium falciparum pyruvate kinase 0.0033 0.0066 0.2056
Mycobacterium ulcerans hypothetical protein 0.0156 0.0462 0.2475
Loa Loa (eye worm) hypothetical protein 0.0013 0.0003 0.0012
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.005 0.0121 0.0121
Mycobacterium ulcerans hypothetical protein 0.0013 0.0002 0.0011
Leishmania major mitochondrial DNA polymerase beta 0.0296 0.0913 1
Echinococcus multilocularis beta adrenergic receptor kinase 0.0023 0.0036 0.0051
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0055 0.0138 0.0738
Entamoeba histolytica hypothetical protein 0.0022 0.0033 0.0084
Brugia malayi CHD4 protein 0.0017 0.0015 0.0054
Trichomonas vaginalis bromodomain-containing protein, putative 0.005 0.0121 0.0312
Trichomonas vaginalis phosphofructokinase, putative 0.0064 0.0167 0.0432
Trypanosoma brucei protein kinase, putative 0.0105 0.03 0.328
Trichomonas vaginalis conserved hypothetical protein 0.0112 0.032 0.0828
Trichomonas vaginalis nuclear lim interactor-interacting factor, putative 0.0014 0.0007 0.0019
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0055 0.0138 0.0738
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0094 0.1029
Brugia malayi SET domain containing protein 0.0019 0.0023 0.0082
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0022 0.0031 0.0081
Loa Loa (eye worm) cytochrome P450 family protein 0.0077 0.021 0.0752
Mycobacterium ulcerans aldehyde dehydrogenase 0.0133 0.0388 0.2075
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0022 0.0031 0.0112
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0025 0.0041 0.0447
Trichomonas vaginalis ap endonuclease, putative 0.0022 0.0031 0.0081
Loa Loa (eye worm) hypothetical protein 0.0013 0.0003 0.0012
Loa Loa (eye worm) hypothetical protein 0.0013 0.0003 0.0012
Trichomonas vaginalis conserved hypothetical protein 0.0112 0.032 0.0828
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0077 0.0209 0.0748
Giardia lamblia NADH oxidase lateral transfer candidate 0.0032 0.0063 0.0164
Plasmodium falciparum JmjC domain-containing protein, putative 0.0018 0.0019 0.0609
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0064 0.0167 0.0355
Brugia malayi regulator of G-protein signaling egl-10 0.0022 0.0033 0.0117
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0878 0.2788 1
Trichomonas vaginalis glutathione reductase, putative 0.0032 0.0063 0.0164
Trichomonas vaginalis nuclear lim interactor-interacting factor, putative 0.0014 0.0007 0.0019
Loa Loa (eye worm) hypothetical protein 0.0058 0.0147 0.0529
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0025 0.0064
Trypanosoma cruzi transcription factor btf3, putative 0.0112 0.032 0.3505
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0013 0.0003 0.0011
Echinococcus multilocularis regulator of G protein signaling 3 0.0022 0.0033 0.0047
Loa Loa (eye worm) hypothetical protein 0.0041 0.0094 0.0337
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0055 0.0138 0.0738
Trichomonas vaginalis DNA helicase recq, putative 0.0047 0.0111 0.0286
Loa Loa (eye worm) cytochrome P450 family protein 0.0074 0.0199 0.0716
Giardia lamblia Pyruvate kinase 0.0017 0.0015 0.0038
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0022 0.0033 0.0117
Trypanosoma brucei DNA polymerase kappa, putative 0.0013 0.0002 0.0022
Toxoplasma gondii pyruvate kinase PyK1 0.0033 0.0066 0.0066
Loa Loa (eye worm) hypothetical protein 0.0026 0.0046 0.0164
Mycobacterium ulcerans DNA polymerase IV 0.0041 0.0094 0.0503
Schistosoma mansoni serine/threonine protein kinase 0.0023 0.0036 0.0051
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0116 0.0334 0.0476
Trichomonas vaginalis DNA helicase recq1, putative 0.0047 0.0111 0.0286
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0055 0.0138 0.1509
Treponema pallidum fructose-bisphosphate aldolase 0.1212 0.3866 1
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0022 0.0031 0.0044
Trypanosoma brucei Mitochondrial import inner membrane translocase subunit TIM50 0.0014 0.0007 0.0079
Loa Loa (eye worm) hypothetical protein 0.0013 0.0003 0.0012
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0033 0.0066 0.0352
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0013 0.0003 0.0009
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0022 0.0031 0.0045
Plasmodium falciparum basic transcription factor 3b, putative 0.0112 0.032 1
Trypanosoma brucei pyruvate kinase 1, putative 0.0033 0.0066 0.0721
Plasmodium vivax hypothetical protein, conserved 0.0013 0.0003 0.0092
Schistosoma mansoni lamin 0.0058 0.0147 0.021
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0021 0.0028 0.0072
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0042 0.0095 0.1035
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0019 0.0023 0.0023
Mycobacterium tuberculosis Probable oxidoreductase 0.0234 0.0714 0.3819
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0077 0.0209 0.2284
Brugia malayi Carboxy-terminal domain RNA polymerase II polypeptide A smallphosphatase 1 0.0014 0.0007 0.0026
Schistosoma mansoni cpg binding protein 0.0063 0.0163 0.0232
Leishmania major DNA polymerase kappa, putative 0.0041 0.0094 0.1029
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0019 0.0023 0.0081
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0032 0.0063 0.0695
Trichomonas vaginalis conserved hypothetical protein 0.0112 0.032 0.0828
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0024 0.0039 0.0211
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0055 0.0138 0.0738
Echinococcus multilocularis 6 phosphofructokinase 0.0237 0.0725 0.1036
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0032 0.0063 1
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0237 0.0725 0.3882
Schistosoma mansoni transcription factor btf3 0.0112 0.032 0.0457
Trypanosoma cruzi DNA damage repair protein, putative 0.0013 0.0002 0.0022
Echinococcus multilocularis lamin 0.0058 0.0147 0.021
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0234 0.0714 0.3819
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0032 0.0063 1
Echinococcus multilocularis regulator of G protein signaling 7 0.0022 0.0033 0.0047
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0032 0.0063 0.0695
Trypanosoma cruzi transcription factor btf3, putative 0.0112 0.032 0.3505
Echinococcus multilocularis Chromo domain 0.0013 0.0003 0.0005
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0058 0.0147 0.0529
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0064 0.0167 0.0167
Trypanosoma cruzi hypothetical protein, conserved 0.0014 0.0007 0.0079
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0003 0.0009
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0013 0.0002 0.0002
Echinococcus multilocularis dnaJ subfamily B 0.0477 0.1497 0.2137
Plasmodium vivax 6-phosphofructokinase, putative 0.0064 0.0167 0.452
Loa Loa (eye worm) hypothetical protein 0.0013 0.0003 0.0012
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0105 0.03 0.1074
Loa Loa (eye worm) hypothetical protein 0.0028 0.0051 0.0182
Plasmodium falciparum pyruvate kinase 2 0.0017 0.0015 0.0456
Schistosoma mansoni mixed-lineage leukemia protein mll 0.002 0.0026 0.0037
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0182 0.0546 0.2923
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0032 0.0063 0.034
Trypanosoma cruzi trypanothione reductase, putative 0.0092 0.0258 0.282
Mycobacterium leprae Probable pyruvate kinase PykA 0.0033 0.0066 0.0352
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0013 0.0003 0.0005
Plasmodium vivax 6-phosphofructokinase, putative 0.0064 0.0167 0.452
Echinococcus multilocularis L aminoadipate semialdehyde 0.0087 0.0241 0.0344
Echinococcus granulosus mitogen activated protein kinase 3 0.0105 0.03 0.0428
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0055 0.0138 0.0738
Echinococcus multilocularis dna polymerase eta 0.0041 0.0094 0.0134
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0032 0.0063 0.0228
Echinococcus granulosus regulator of G protein signaling 3 0.0022 0.0033 0.0047
Trichomonas vaginalis pyruvate kinase, putative 0.0033 0.0066 0.017
Trichomonas vaginalis phosphofructokinase, putative 0.0064 0.0167 0.0432
Plasmodium falciparum glutathione reductase 0.0032 0.0063 0.1983
Echinococcus granulosus histone acetyltransferase KAT2B 0.005 0.0121 0.0172
Onchocerca volvulus Pyruvate kinase homolog 0.0033 0.0066 0.0207
Brugia malayi CXXC zinc finger family protein 0.0063 0.0163 0.0583
Schistosoma mansoni hypothetical protein 0.0013 0.0003 0.0005
Leishmania major hypothetical protein, conserved 0.0018 0.0019 0.0213
Loa Loa (eye worm) hypothetical protein 0.0022 0.0033 0.0117
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0094 0.1029
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0055 0.0138 0.0738
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0013 0.0002 0.0002
Trichomonas vaginalis chromobox protein, putative 0.0013 0.0003 0.0009
Toxoplasma gondii LsmAD domain-containing protein 0.0026 0.0046 0.0046
Schistosoma mansoni z-protein (S1r protein) 0.0022 0.0033 0.0047
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0064 0.0167 1
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0237 0.0725 0.181
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0055 0.0138 0.0738
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0032 0.0063 0.0695
Entamoeba histolytica deoxycytidyl transferase, putative 0.0041 0.0094 0.0243
Trypanosoma cruzi DNA polymerase kappa, putative 0.0041 0.0094 0.1029
Echinococcus granulosus CTD small phosphatase protein like 0.0014 0.0007 0.001
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0013 0.0002 0.0002
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0055 0.0138 0.0738
Brugia malayi jmjC domain containing protein 0.0069 0.0182 0.0651
Echinococcus multilocularis 0.0055 0.0138 0.0197
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0055 0.0138 0.0738
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0182 0.0546 0.078
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0032 0.0063 0.0695
Loa Loa (eye worm) hypothetical protein 0.0118 0.0341 0.1223
Leishmania major DNA polymerase eta, putative 0.0013 0.0002 0.0022
Trypanosoma cruzi cytochrome P450, putative 0.0074 0.0199 0.2184
Plasmodium vivax SET domain protein, putative 0.0127 0.037 1
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.014 0.0413 0.0589
Loa Loa (eye worm) RGS-3 protein 0.0022 0.0033 0.0117
Loa Loa (eye worm) glutaminase 0.0319 0.0988 0.3542
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0018 0.0019 0.0213
Brugia malayi jmjC domain containing protein 0.0018 0.0019 0.007
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0182 0.0546 0.598
Echinococcus granulosus histone lysine methyltransferase setb 0.0127 0.037 0.0528
Schistosoma mansoni terminal deoxycytidyl transferase 0.0041 0.0094 0.0134
Trichomonas vaginalis glutaminase, putative 0.0319 0.0988 0.2554
Schistosoma mansoni 6-phosphofructokinase 0.0237 0.0725 0.1036
Schistosoma mansoni intermediate filament proteins 0.0058 0.0147 0.021
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0032 0.0063 0.0695
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0019 0.0023 0.0023
Brugia malayi Heterochromatin protein 1 0.0013 0.0003 0.0012
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0022 0.0031 0.0167
Giardia lamblia Kinase, CMGC MAPK 0.0105 0.03 0.0775
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0055 0.0138 0.0738
Schistosoma mansoni serine/threonine protein kinase 0.0023 0.0036 0.0051
Plasmodium vivax basic transcription factor 3b, putative 0.0112 0.032 0.8656
Leishmania major pyruvate kinase 0.0033 0.0066 0.0721
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0022 0.0031 0.0342
Echinococcus granulosus expressed protein 0.0435 0.1363 0.1946
Schistosoma mansoni pyruvate kinase 0.0017 0.0015 0.0021
Trichomonas vaginalis Heterochromatin protein, putative 0.0013 0.0003 0.0009
Echinococcus granulosus Chromo domain 0.0013 0.0003 0.0005
Brugia malayi hypothetical protein 0.0142 0.0418 0.1499
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0087 0.0241 0.0344
Onchocerca volvulus Pyruvate kinase homolog 0.0033 0.0066 0.0207
Plasmodium vivax NLI interacting factor-like phosphatase, putative 0.0014 0.0007 0.0194
Brugia malayi cytochrome P450 0.0055 0.0138 0.0494
Loa Loa (eye worm) pyruvate kinase 0.0033 0.0066 0.0236
Echinococcus multilocularis JmjC domain containing protein 4 0.0018 0.0019 0.0028
Entamoeba histolytica hypothetical protein 0.0013 0.0003 0.0009
Echinococcus multilocularis pyruvate kinase 0.0017 0.0015 0.0021
Loa Loa (eye worm) hypothetical protein 0.0118 0.0341 0.1223
Brugia malayi hypothetical protein 0.0022 0.0033 0.0117
Echinococcus multilocularis pyruvate kinase 0.0033 0.0066 0.0094
Leishmania major hypothetical protein, conserved 0.0014 0.0007 0.0079
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.014 0.0412 0.4505
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0028 0.0072
Trichomonas vaginalis chromobox protein, putative 0.0013 0.0003 0.0009
Trypanosoma cruzi hypothetical protein, conserved 0.0013 0.0002 0.0022
Trypanosoma cruzi DNA polymerase eta, putative 0.0041 0.0094 0.1029
Brugia malayi jmjC domain containing protein 0.0018 0.0019 0.007
Echinococcus multilocularis mixed lineage leukemia protein mll 0.002 0.0026 0.0037
Echinococcus multilocularis transcription factor Dp 1 0.0045 0.0104 0.0149
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0055 0.0138 0.0738
Echinococcus granulosus dna polymerase kappa 0.0041 0.0094 0.0134
Trypanosoma brucei DNA polymerase IV, putative 0.0041 0.0094 0.1029
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0006 0.0016
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0055 0.0138 0.0738
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0022 0.0031 0.0342
Giardia lamblia Sgs1 DNA helicase, putative 0.0019 0.0023 0.0058
Brugia malayi Pyruvate kinase, muscle isozyme 0.0033 0.0066 0.0236
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0077 0.0209 0.2284
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0055 0.0138 0.0738
Toxoplasma gondii phosphofructokinase PFKII 0.0064 0.0167 0.0167
Loa Loa (eye worm) thioredoxin reductase 0.0092 0.0258 0.0924
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0055 0.0138 0.0738
Schistosoma mansoni axis inhibition protein axin 0.0022 0.0033 0.0047
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0105 0.03 0.328
Echinococcus multilocularis dna polymerase kappa 0.0041 0.0094 0.0134
Loa Loa (eye worm) hypothetical protein 0.0127 0.037 0.1327
Schistosoma mansoni hypothetical protein 0.006 0.0155 0.0221
Echinococcus multilocularis axis inhibition protein axin 0.0022 0.0033 0.0047
Mycobacterium leprae Conserved hypothetical protein 0.0055 0.0138 0.0738
Loa Loa (eye worm) hypothetical protein 0.0022 0.0033 0.0117
Schistosoma mansoni pyruvate kinase 0.0033 0.0066 0.0094
Loa Loa (eye worm) hypothetical protein 0.037 0.1152 0.4133
Trichomonas vaginalis CMGC family protein kinase 0.0105 0.03 0.0775
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0003 0.0009
Echinococcus granulosus Ankyrin repeat domain containing protein 0.0105 0.0298 0.0426
Schistosoma mansoni hypothetical protein 0.0014 0.0007 0.0009
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0032 0.0063 0.0091
Toxoplasma gondii pyruvate kinase PyKII 0.0017 0.0015 0.0015

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) > 100 uM The compound was tested for the inhibitory activity of FK506 binding protein ChEMBL. 1447733

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

No external resources registered for this compound

Bibliographic References

1 literature reference was collected for this gene.

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