Detailed information for compound 424065

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 555.625 | Formula: C32H44Cl2N4
  • H donors: 2 H acceptors: 0 LogP: 10 Rotable bonds: 13
    Rule of 5 violations (Lipinski): 2
  • SMILES: Nc1cc(C)[n+](c2c1cccc2)CCCCCCCCCCCC[n+]1c(C)cc(c2c1cccc2)N.[Cl-].[Cl-]
  • InChi: 1S/C32H42N4.2ClH/c1-25-23-29(33)27-17-11-13-19-31(27)35(25)21-15-9-7-5-3-4-6-8-10-16-22-36-26(2)24-30(34)28-18-12-14-20-32(28)36;;/h11-14,17-20,23-24,33-34H,3-10,15-16,21-22H2,1-2H3;2*1H
  • InChiKey: YQDOXSAJOLACNP-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Plasmodium falciparum protein kinase 7 0.0563 0.5584 0.6602
Schistosoma mansoni calcium-activated potassium channel 0.0023 0.0115 0.0115
Trypanosoma brucei glucose transporter, putative 0.0061 0.0503 0.1635
Schistosoma mansoni glucose transport protein 0.0198 0.189 0.189
Toxoplasma gondii LsmAD domain-containing protein 0.0018 0.0059 0.0081
Echinococcus granulosus RUN 0.0016 0.0041 0.0041
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0085 0.0142
Echinococcus multilocularis synaptic vesicle 2 protein 0.0028 0.0163 0.0163
Schistosoma mansoni glucose transport protein 0.0198 0.189 0.189
Echinococcus multilocularis ubiquitin conjugating enzyme E2 N 0.0314 0.3068 0.3068
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0059 0.0483 0.5152
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0132 0.122 0.3975
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0145 0.0242
Entamoeba histolytica recQ family helicase, putative 0.0017 0.0052 0.0169
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0086 0.0753 0.2454
Schistosoma mansoni polycystin 1-related 0.0016 0.0041 0.0041
Schistosoma mansoni hypothetical protein 0.0198 0.189 0.189
Schistosoma mansoni lipoxygenase 0.0095 0.0845 0.0845
Trypanosoma brucei THT1 - hexose transporter, putative 0.0061 0.0503 0.1635
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0021 0.0097 0.0159
Schistosoma mansoni serine/threonine protein kinase 0.0086 0.0753 0.0753
Plasmodium vivax SET domain protein, putative 0.0035 0.0239 0.0236
Mycobacterium ulcerans endonuclease IV 0.0093 0.0818 0.3121
Onchocerca volvulus 0.0023 0.0115 0.0367
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0093 0.0155
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0021 0.0093 0.0296
Loa Loa (eye worm) cytochrome P450 family protein 0.0015 0.0031 0.005
Brugia malayi Neuronal symmetry protein 1 0.0076 0.0653 0.2129
Plasmodium falciparum cysteine proteinase falcipain 2b 0.002 0.0085 0.0052
Brugia malayi Sugar transporter family protein 0.0028 0.0163 0.053
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0018 0.0059 0.0191
Mycobacterium ulcerans epimerase 0.0024 0.0127 0.0381
Onchocerca volvulus 0.0028 0.0163 0.0547
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0163 0.0271
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0059 0.0483 0.1575
Echinococcus multilocularis serine:threonine protein kinase N2 0.0146 0.1361 0.1361
Onchocerca volvulus 0.0028 0.0163 0.0547
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0034 0.0227 0.0227
Schistosoma mansoni twik family of potassium channels-related 0.0023 0.0115 0.0115
Trypanosoma brucei DNA polymerase kappa, putative 0.005 0.0383 0.1241
Trypanosoma cruzi cruzipain precursor, putative 0.0077 0.0661 0.2155
Echinococcus multilocularis solute carrier family 22 0.0028 0.0163 0.0163
Schistosoma mansoni sugar transporter 0.0028 0.0163 0.0163
Brugia malayi cytoplasmic intermediate filament protein 0.0017 0.0057 0.0185
Brugia malayi intermediate filament protein 0.0033 0.021 0.0685
Toxoplasma gondii facilitative glucose transporter GT1 0.0198 0.189 0.3369
Schistosoma mansoni vav2 0.0047 0.0359 0.0359
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0021 0.0097 0.0097
Trichomonas vaginalis sugar transporter, putative 0.0028 0.0163 0.0271
Brugia malayi hypothetical protein 0.0018 0.0059 0.0191
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0013 0.0014 0.0038
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0093 0.0155
Echinococcus multilocularis cpg binding protein 0.0037 0.0252 0.0252
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0093 0.0155
Plasmodium falciparum potassium channel 0.0023 0.0115 0.0087
Toxoplasma gondii protein kinase, putative 0.0563 0.5584 1
Loa Loa (eye worm) potassium voltage-gated channel subfamily Q member 5 0.0023 0.0115 0.0189
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0085 0.0142
Brugia malayi Major Facilitator Superfamily protein 0.0028 0.0163 0.053
Loa Loa (eye worm) hypothetical protein 0.0014 0.0017 0.0028
Echinococcus multilocularis ecdysone induced protein 78C 0.0021 0.0097 0.0097
Loa Loa (eye worm) hypothetical protein 0.0023 0.0115 0.0189
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0086 0.0753 0.2448
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0261 0.0843
Mycobacterium ulcerans phosphotyrosine protein phosphatase PtpA 0.0264 0.2555 1
Echinococcus granulosus epidermal growth factor receptor 0.01 0.0892 0.0892
Trichomonas vaginalis low molecular weight protein-tyrosine-phosphatase, putative 0.0264 0.2555 0.4262
Echinococcus granulosus cathepsin L cysteine proteinase 0.002 0.0085 0.0085
Schistosoma mansoni twik family of potassium channels-related 0.0023 0.0115 0.0115
Plasmodium vivax potassium channel, putative 0.0023 0.0115 0.0087
Schistosoma mansoni cellular tumor antigen P53 0.006 0.0486 0.0486
Brugia malayi Bloom's syndrome protein homolog 0.005 0.0384 0.1251
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 21 0.0023 0.0115 0.0374
Echinococcus multilocularis epidermal growth factor receptor 0.0054 0.0424 0.0424
Onchocerca volvulus 0.0023 0.0115 0.0367
Trichomonas vaginalis sugar transporter, putative 0.0028 0.0163 0.0271
Plasmodium vivax CDK-related protein kinase 6, putative 0.0844 0.8437 1
Brugia malayi Inositol-1 0.0045 0.0332 0.1083
Schistosoma mansoni hypothetical protein 0.061 0.6066 0.6066
Loa Loa (eye worm) CXXC zinc finger family protein 0.0035 0.0232 0.0382
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 5 0.0023 0.0115 0.0374
Echinococcus multilocularis cysteine protease 0.002 0.0085 0.0085
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0021 0.0093 0.0093
Giardia lamblia Sugar-proton symporter 0.0028 0.0163 0.0284
Trypanosoma brucei DNA polymerase kappa, putative 0.005 0.0383 0.1241
Echinococcus granulosus twik family of potassium channels 0.0023 0.0115 0.0115
Loa Loa (eye worm) hypothetical protein 0.0028 0.0163 0.0268
Entamoeba histolytica hypothetical protein 0.0044 0.0329 0.1071
Toxoplasma gondii ubiquitin-conjugating enzyme subfamily protein 0.0314 0.3068 0.5483
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0172 0.0287
Trypanosoma cruzi PAB1-binding protein , putative 0.0018 0.0059 0.0191
Echinococcus multilocularis serine threonine protein kinase 0.0137 0.127 0.127
Schistosoma mansoni tyrosine kinase 0.0054 0.0424 0.0424
Trichomonas vaginalis low molecular weight protein-tyrosine-phosphatase, putative 0.0264 0.2555 0.4262
Echinococcus multilocularis protein kinase c epsilon type 0.0195 0.1855 0.1855
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0264 0.2555 0.4262
Trichomonas vaginalis sugar transporter, putative 0.0028 0.0163 0.0271
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0034 0.0227 0.0227
Echinococcus granulosus tumor protein p63 0.0408 0.4017 0.4017
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0021 0.0097 0.0315
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0063 0.052 0.052
Loa Loa (eye worm) hypothetical protein 0.0238 0.2294 0.3782
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0453 0.0755
Schistosoma mansoni serine/threonine protein kinase 0.0054 0.0425 0.0425
Leishmania major phosphatidylinositol 3-kinase, putative 0.0021 0.0093 0.0205
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.004 0.0285 0.0797
Echinococcus granulosus myotubularin protein 13 0.0047 0.0359 0.0359
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0028 0.0163 0.0163
Echinococcus multilocularis neuropeptide s receptor 0.0558 0.5542 0.5542
Loa Loa (eye worm) hypothetical protein 0.0023 0.0115 0.0189
Leishmania major basic transcription factor 3a, putative 0.0026 0.0145 0.0376
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.008 0.069 0.069
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0085 0.0142
Plasmodium falciparum ubiquitin-conjugating enzyme E2 N, putative 0.0314 0.3068 0.3605
Echinococcus granulosus X box binding protein 1 0.0215 0.2063 0.2063
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 45 0.0023 0.0115 0.0374
Trypanosoma brucei sugar transporter, putative 0.0028 0.0163 0.0523
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0085 0.0142
Schistosoma mansoni twik family of potassium channels-related 0.0023 0.0115 0.0115
Trypanosoma brucei DNA polymerase kappa, putative 0.005 0.0383 0.1241
Echinococcus granulosus twik family of potassium channels 0.0023 0.0115 0.0115
Brugia malayi Low molecular weight phosphotyrosine protein phosphatase containing protein 0.0264 0.2555 0.8328
Brugia malayi beta-NAC-like protein 0.0026 0.0145 0.0472
Trypanosoma cruzi target of rapamycin kinase 3 0.0021 0.0093 0.0303
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0035 0.023 0.023
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0035 0.023 0.038
Brugia malayi ImpB/MucB/SamB family protein 0.0017 0.0057 0.0186
Brugia malayi RhoGAP domain containing protein 0.0044 0.0331 0.1079
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.0028 0.0163 0.0523
Loa Loa (eye worm) hypothetical protein 0.0028 0.0163 0.0268
Loa Loa (eye worm) TK/EGFR protein kinase 0.01 0.0892 0.147
Loa Loa (eye worm) hypothetical protein 0.0015 0.0033 0.0055
Echinococcus multilocularis cathepsin l cysteine peptidase 0.002 0.0085 0.0085
Onchocerca volvulus 0.0081 0.0706 0.259
Schistosoma mansoni nuclear hormone receptor 0.0021 0.0097 0.0097
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0093 0.0155
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0198 0.189 0.189
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0085 0.0142
Trichomonas vaginalis DNA polymerase eta, putative 0.005 0.0383 0.0639
Plasmodium falciparum calcium-dependent protein kinase 1 0.0063 0.052 0.057
Echinococcus multilocularis potassium channel subfamily K 0.0023 0.0115 0.0115
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0085 0.0142
Schistosoma mansoni diacylglycerol kinase theta 0.0044 0.0331 0.0331
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0029 0.0172 0.0562
Echinococcus multilocularis microtubule associated protein 2 0.0998 1 1
Brugia malayi Major Facilitator Superfamily protein 0.0028 0.0163 0.053
Brugia malayi F/Y-rich N-terminus family protein 0.0012 0 0.0001
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0093 0.0155
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0145 0.0242
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0021 0.0097 0.0097
Schistosoma mansoni thyroid hormone receptor 0.0021 0.0097 0.0097
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.005 0.0383 0.0639
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0021 0.0097 0.0097
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0038 0.0262 0.0855
Echinococcus granulosus neuropeptide s receptor 0.0558 0.5542 0.5542
Trypanosoma cruzi cysteine peptidase, putative 0.0077 0.0661 0.2155
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0021 0.0093 0.0205
Leishmania major potassium channel subunit-like protein 0.0023 0.0115 0.0277
Schistosoma mansoni protein kinase C mu 0.0044 0.0331 0.0331
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0044 0.0331 0.0331
Echinococcus granulosus inositol monophosphatase 1 0.0045 0.0332 0.0332
Onchocerca volvulus 0.0028 0.0163 0.0547
Plasmodium falciparum calcium-dependent protein kinase 3 0.0063 0.052 0.057
Loa Loa (eye worm) hypothetical protein 0.0023 0.0115 0.0189
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.0097 0.0315
Schistosoma mansoni protein kinase C mu 0.0132 0.122 0.122
Schistosoma mansoni retinoic acid receptor RXR 0.0021 0.0097 0.0097
Plasmodium vivax potassium channel, putative 0.0023 0.0115 0.0087
Onchocerca volvulus 0.002 0.0085 0.0255
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0021 0.0097 0.0315
Entamoeba histolytica cysteine proteinase, putative 0.002 0.0085 0.0277
Loa Loa (eye worm) hypothetical protein 0.0028 0.0163 0.0268
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0059 0.0483 0.0483
Echinococcus granulosus insulin receptor 0.0032 0.0203 0.0203
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0035 0.0239 0.0239
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0093 0.0155
Loa Loa (eye worm) hypothetical protein 0.0028 0.0163 0.0268
Mycobacterium ulcerans integral membrane transport protein 0.0028 0.0163 0.0523
Brugia malayi CXXC zinc finger family protein 0.0035 0.0232 0.0755
Entamoeba histolytica recQ family helicase, putative 0.0038 0.0262 0.0855
Onchocerca volvulus 0.0023 0.0115 0.0367
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0023 0.0115 0.0191
Echinococcus granulosus lipoxygenase domain containing protein 0.0016 0.0041 0.0041
Echinococcus granulosus potassium channel subfamily K 8 0.0023 0.0115 0.0115
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0097 0.0097
Trypanosoma brucei THT1 - hexose transporter, putative 0.0061 0.0503 0.1635
Trichomonas vaginalis DNA helicase recq, putative 0.0038 0.0262 0.0437
Trypanosoma brucei unspecified product 0.0042 0.0302 0.0978
Schistosoma mansoni tyrosine kinase 0.0053 0.0418 0.0418
Loa Loa (eye worm) STE/STE11/ASK protein kinase 0.0027 0.0157 0.0259
Echinococcus granulosus Sugar transporter ERD6 protein 0.0028 0.0163 0.0163
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0054 0.0425 0.0425
Toxoplasma gondii cathepsin CPL 0.002 0.0085 0.0128
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0063 0.052 0.052
Loa Loa (eye worm) sugar transporter 0.0198 0.189 0.3116
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0198 0.189 0.189
Loa Loa (eye worm) hypothetical protein 0.0023 0.0115 0.0189
Plasmodium vivax ataxin-2 like protein, putative 0.0018 0.0059 0.0021
Toxoplasma gondii FATC domain-containing protein 0.0029 0.0172 0.0285
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0035 0.0239 0.0239
Loa Loa (eye worm) hypothetical protein 0.0023 0.0115 0.0189
Mycobacterium ulcerans DNA polymerase IV 0.005 0.0383 0.1395
Echinococcus multilocularis serine protein kinase ATM 0.0029 0.0172 0.0172
Brugia malayi hypothetical protein 0.0016 0.0041 0.0134
Loa Loa (eye worm) hypothetical protein 0.0023 0.0115 0.0189
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0085 0.0142
Loa Loa (eye worm) hypothetical protein 0.0033 0.0212 0.035
Onchocerca volvulus 0.0023 0.0115 0.0367
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0033 0.021 0.0346
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0051 0.0394 0.0394
Onchocerca volvulus Cathepsin L homolog 0.002 0.0085 0.0255
Onchocerca volvulus 0.0264 0.2555 0.9545
Echinococcus granulosus dna polymerase kappa 0.005 0.0383 0.0383
Echinococcus granulosus synaptic vesicle 2 protein 0.0028 0.0163 0.0163
Echinococcus multilocularis transcription factor btf3 0.0026 0.0145 0.0145
Trypanosoma brucei PAB1-binding protein , putative 0.0018 0.0059 0.0184
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0044 0.0331 0.0331
Loa Loa (eye worm) hypothetical protein 0.0021 0.0097 0.0159
Schistosoma mansoni microtubule-associated protein tau 0.0998 1 1
Onchocerca volvulus 0.0028 0.0163 0.0547
Trypanosoma brucei DNA polymerase kappa, putative 0.005 0.0383 0.1241
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0029 0.0172 0.0562
Schistosoma mansoni serine/threonine protein kinase 0.0054 0.0425 0.0425
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0021 0.0097 0.0159
Schistosoma mansoni lysyl-tRNA synthetase 0.0044 0.0329 0.0329
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0034 0.0227 0.0227
Echinococcus granulosus protein kinase c iota type 0.0153 0.1435 0.1435
Trichomonas vaginalis sugar transporter, putative 0.0061 0.0503 0.084
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0021 0.0093 0.0205
Loa Loa (eye worm) hypothetical protein 0.0018 0.0059 0.0097
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0021 0.0097 0.0097
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0021 0.0097 0.0159
Leishmania major cathepsin L-like protease 0.0077 0.0661 0.2076
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.002 0.0085 0.014
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0035 0.023 0.023
Trichomonas vaginalis sugar transporter, putative 0.0028 0.0163 0.0271
Onchocerca volvulus 0.0113 0.1025 0.379
Trichomonas vaginalis inositol monophosphatase, putative 0.0045 0.0332 0.0554
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0093 0.0155
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0086 0.0753 0.0753
Echinococcus multilocularis cathepsin L cysteine protease 0.002 0.0085 0.0085
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0044 0.0331 0.0331
Leishmania major hypothetical protein, conserved 0.0018 0.0059 0.0092
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.007 0.0593 0.1934
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0063 0.052 0.052
Loa Loa (eye worm) hypothetical protein 0.0037 0.0258 0.0425
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0063 0.052 0.057
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0021 0.0097 0.0097
Echinococcus granulosus transcription factor btf3 0.0026 0.0145 0.0145
Echinococcus multilocularis RUN 0.0016 0.0041 0.0041
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0044 0.0331 0.0546
Leishmania major cathepsin L-like protease 0.002 0.0085 0.0179
Onchocerca volvulus 0.002 0.0085 0.0255
Mycobacterium ulcerans hypothetical protein 0.0024 0.0127 0.0381
Brugia malayi Cathepsin L-like cysteine proteinase 0.0014 0.0017 0.0056
Trypanosoma brucei ubiquitin-protein ligase, putative 0.0314 0.3068 1
Trypanosoma cruzi hexose transporter, putative 0.0028 0.0163 0.053
Loa Loa (eye worm) hypothetical protein 0.0023 0.0115 0.0189
Schistosoma mansoni tyrosine kinase 0.0054 0.0424 0.0424
Loa Loa (eye worm) hypothetical protein 0.0023 0.0115 0.0189
Loa Loa (eye worm) hypothetical protein 0.007 0.0591 0.0974
Onchocerca volvulus 0.0023 0.0115 0.0367
Echinococcus multilocularis protein kinase c iota type 0.0153 0.1435 0.1435
Loa Loa (eye worm) fibroinase 0.002 0.0085 0.014
Echinococcus multilocularis X box binding protein 1 0.0215 0.2063 0.2063
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 0.0314 0.3068 0.5058
Plasmodium vivax proline--tRNA ligase, putative 0.0069 0.0583 0.0645
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0025 0.0138 0.0283
Echinococcus granulosus RNA directed DNA polymerase 0.0079 0.0682 0.0682
Mycobacterium tuberculosis Phosphotyrosine protein phosphatase PtpA (protein-tyrosine-phosphatase) (PTPase) (LMW phosphatase) 0.0264 0.2555 0.8751
Entamoeba histolytica transcription factor BTF3, putative 0.0026 0.0145 0.0472
Echinococcus multilocularis neuropeptide receptor A26 0.0558 0.5542 0.5542
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0021 0.0097 0.0097
Toxoplasma gondii sugar transporter ST3 0.0028 0.0163 0.0267
Loa Loa (eye worm) TWK-7 protein 0.0023 0.0115 0.0189
Leishmania major protein kinase A catalytic subunit isoform 2 0.0086 0.0753 0.2378
Plasmodium falciparum hexose transporter 0.0198 0.189 0.2202
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0086 0.0753 0.0753
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0012 0.0002 0.0002
Entamoeba histolytica hypothetical protein 0.0044 0.0331 0.1079
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0314 0.3068 0.5118
Echinococcus multilocularis RNA directed DNA polymerase 0.0079 0.0682 0.0682
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0093 0.0155
Schistosoma mansoni survival motor neuron protein 0.0058 0.0471 0.0471
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0093 0.0155
Trypanosoma brucei Enriched in surface-labeled proteome protein 12 0.0105 0.0944 0.3072
Plasmodium vivax ubiquitin-conjugating enzyme E2 N, putative 0.0314 0.3068 0.3605
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.002 0.0085 0.0142
Onchocerca volvulus 0.0129 0.1185 0.4391
Plasmodium falciparum basic transcription factor 3b, putative 0.0026 0.0145 0.0123
Echinococcus granulosus FTZ F1 alpha 0.0021 0.0097 0.0097
Toxoplasma gondii diacylglycerol kinase, putative 0.0044 0.0331 0.057
Onchocerca volvulus 0.0016 0.0041 0.0091
Echinococcus multilocularis geminin 0.0205 0.1955 0.1955
Loa Loa (eye worm) hypothetical protein 0.0135 0.125 0.2061
Echinococcus granulosus ecdysone induced protein 78C 0.0021 0.0097 0.0097
Leishmania major cathepsin L-like protease 0.0077 0.0661 0.2076
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0035 0.023 0.023
Loa Loa (eye worm) hypothetical protein 0.0185 0.1752 0.2889
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.0024 0.0127 0.0413
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.002 0.0085 0.0142
Trypanosoma cruzi hexose transporter, putative 0.0061 0.0503 0.1641
Schistosoma mansoni glucose transport protein 0.0198 0.189 0.189
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0021 0.0097 0.0315
Brugia malayi Protein kinase domain containing protein 0.0051 0.0394 0.1283
Plasmodium falciparum lysine--tRNA ligase 0.0044 0.0329 0.0342
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0059 0.0483 0.0483
Loa Loa (eye worm) hypothetical protein 0.0016 0.0039 0.0065
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0069 0.0583 0.19
Echinococcus granulosus TWiK family of potassium channels protein 7 0.0023 0.0115 0.0115
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 38. C. elegans sup-9 ortholog 0.0023 0.0115 0.0374
Brugia malayi nuclear receptor NHR-88 0.0021 0.0097 0.0315
Trichomonas vaginalis sugar transporter, putative 0.0028 0.0163 0.0271
Schistosoma mansoni twik family of potassium channels-related 0.0023 0.0115 0.0115
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0054 0.0425 0.0425
Leishmania major phosphatidylinositol kinase related protein, putative 0.0021 0.0093 0.0206
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0021 0.0093 0.0205
Loa Loa (eye worm) CYP4Cod1 0.0015 0.0031 0.005
Onchocerca volvulus 0.002 0.0085 0.0255
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0063 0.052 0.0909
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0014 0.0017 0.0029
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0044 0.0329 0.2919
Echinococcus multilocularis C2 calcium dependent membrane targeting 0.0049 0.0374 0.0374
Schistosoma mansoni intermediate filament proteins 0.0033 0.021 0.021
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0069 0.0583 0.1895
Giardia lamblia Prolyl-tRNA synthetase 0.0059 0.0483 0.1585
Onchocerca volvulus 0.0028 0.0163 0.0547
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.008 0.0688 0.2165
Echinococcus multilocularis unc 13 (munc13) 0.0049 0.0374 0.0374
Trichomonas vaginalis sugar transporter, putative 0.0028 0.0163 0.0271
Schistosoma mansoni unc-13 (munc13) 0.0049 0.0374 0.0374
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0063 0.052 0.057
Toxoplasma gondii AGC kinase 0.0086 0.0753 0.1327
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0035 0.023 0.023
Entamoeba histolytica protein kinase, putative 0.0056 0.0453 0.1476
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0093 0.0155
Echinococcus multilocularis dna polymerase kappa 0.005 0.0383 0.0383
Loa Loa (eye worm) hypothetical protein 0.0059 0.0483 0.0796
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0085 0.0142
Brugia malayi hypothetical protein 0.0028 0.0163 0.053
Trypanosoma brucei glucose transporter, putative 0.0061 0.0503 0.1635
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0034 0.0227 0.0373
Trichomonas vaginalis sugar transporter, putative 0.0028 0.0163 0.0271
Brugia malayi major facilitator superfamily protein 0.0028 0.0163 0.053
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.0028 0.0163 0.0523
Loa Loa (eye worm) hypothetical protein 0.006 0.0486 0.08
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0085 0.0142
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0025 0.0131 0.0428
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 12 0.0023 0.0115 0.0374
Entamoeba histolytica cysteine proteinase, putative 0.002 0.0085 0.0277
Schistosoma mansoni unc-13 (munc13) 0.0049 0.0374 0.0374
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0028 0.0163 0.0145
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0017 0.0057 0.0057
Loa Loa (eye worm) hypothetical protein 0.0023 0.0115 0.0189
Echinococcus granulosus unc 13 munc13 0.0049 0.0374 0.0374
Trichomonas vaginalis sugar transporter, putative 0.0028 0.0163 0.0271
Echinococcus granulosus solute carrier family 22 0.0028 0.0163 0.0163
Trypanosoma cruzi hypothetical protein, conserved 0.0023 0.0115 0.0374
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0021 0.0097 0.0097
Echinococcus granulosus bloom syndrome protein 0.005 0.0384 0.0384
Loa Loa (eye worm) hypothetical protein 0.0081 0.0706 0.1164
Schistosoma mansoni serine/threonine protein kinase 0.0195 0.1855 0.1855
Trypanosoma brucei DNA polymerase eta, putative 0.0017 0.0057 0.0179
Leishmania major ubiquitin-conjugating enzyme e2, putative 0.0314 0.3068 1
Plasmodium falciparum ataxin-2 like protein, putative 0.0018 0.0059 0.0021
Trypanosoma cruzi ion transport protein, putative 0.0023 0.0115 0.0374
Trypanosoma brucei THT1 - hexose transporter, putative 0.0061 0.0503 0.1635
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0035 0.023 0.0751
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0086 0.0753 0.2448
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0033 0.0218 0.0218
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0093 0.0155
Loa Loa (eye worm) hypothetical protein 0.0013 0.0014 0.0023
Loa Loa (eye worm) intermediate filament protein 0.0033 0.021 0.0346
Trichomonas vaginalis conserved hypothetical protein 0.0603 0.5994 1
Loa Loa (eye worm) AGC/AKT protein kinase 0.0056 0.0453 0.0746
Brugia malayi Twik (KCNK-like) family of potasium channels, alpha subunit 40 0.0023 0.0115 0.0374
Brugia malayi Calcitonin receptor-like protein seb-1 0.0037 0.0258 0.084
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0023 0.0115 0.0191
Brugia malayi Protein kinase domain containing protein 0.0054 0.0425 0.1385
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.0661 0.2149
Loa Loa (eye worm) AGC/NDR protein kinase 0.0054 0.0425 0.07
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0021 0.0097 0.0315
Loa Loa (eye worm) histone methyltransferase 0.0012 0.0002 0.0003
Onchocerca volvulus 0.0035 0.0232 0.0806
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0021 0.0093 0.0303
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0097 0.0315
Onchocerca volvulus 0.002 0.0085 0.0255
Schistosoma mansoni DNA helicase recq1 0.0035 0.023 0.023
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0093 0.0818 1
Brugia malayi hypothetical protein 0.0028 0.0163 0.053
Echinococcus granulosus cathepsin l1 0.002 0.0085 0.0085
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0018 0.0059 0.0191
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0016 0.0039 0.0039
Schistosoma mansoni thyroid hormone receptor 0.0021 0.0097 0.0097
Trichomonas vaginalis sugar transporter, putative 0.0028 0.0163 0.0271
Loa Loa (eye worm) hypothetical protein 0.0017 0.0057 0.0094
Trypanosoma cruzi Enriched in surface-labeled proteome protein 12 0.0105 0.0944 0.3077
Schistosoma mansoni twik family of potassium channels-related 0.0023 0.0115 0.0115
Echinococcus multilocularis inositol monophosphatase 1 0.0045 0.0332 0.0332
Echinococcus multilocularis Rac GTPase activating protein 1 0.0044 0.0331 0.0331
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0035 0.0239 0.0239
Brugia malayi Cathepsin L-like precursor 0.0014 0.0017 0.0056
Echinococcus multilocularis serine:threonine protein kinase N2 0.0054 0.0425 0.0425
Brugia malayi hypothetical protein 0.0028 0.0163 0.053
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0093 0.0818 0.0926
Onchocerca volvulus 0.0028 0.0163 0.0547
Schistosoma mansoni serine/threonine protein kinase 0.0086 0.0753 0.0753
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0016 0.0039 0.0039
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0453 0.0755
Loa Loa (eye worm) phosphatidylinositol 3 0.0021 0.0093 0.0153
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0097 0.0315
Trichomonas vaginalis sugar transporter, putative 0.0028 0.0163 0.0271
Toxoplasma gondii NAC domain-containing protein 0.0026 0.0145 0.0235
Entamoeba histolytica diacylglycerol kinase, putative 0.0044 0.0331 0.1079
Chlamydia trachomatis endonuclease IV 0.0093 0.0818 1
Schistosoma mansoni lipoxygenase 0.0067 0.0555 0.0555
Trypanosoma brucei transcription factor BTF3, putative 0.0026 0.0145 0.0465
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0323 0.3153 0.3706
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0069 0.0583 0.1819
Toxoplasma gondii ion channel protein 0.0023 0.0115 0.0181
Trichomonas vaginalis sugar transporter, putative 0.0028 0.0163 0.0271
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0014 0.0023
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0085 0.0142
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0045 0.0332 0.1083
Loa Loa (eye worm) hypothetical protein 0.0035 0.023 0.038
Onchocerca volvulus 0.0021 0.0097 0.0298
Trypanosoma cruzi Enriched in surface-labeled proteome protein 12 0.0105 0.0944 0.3077
Loa Loa (eye worm) hypothetical protein 0.0023 0.0115 0.0189
Schistosoma mansoni inositol monophosphatase 0.0045 0.0332 0.0332
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0242 0.2337 0.3853
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0264 0.2555 0.4262
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0025 0.0138 0.0354
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0063 0.052 0.057
Onchocerca volvulus 0.0023 0.0115 0.0367
Schistosoma mansoni tyrosine kinase 0.01 0.0892 0.0892
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0261 0.0843
Trichomonas vaginalis conserved hypothetical protein 0.0061 0.0503 0.084
Trypanosoma brucei DNA polymerase kappa, putative 0.005 0.0383 0.1241
Brugia malayi steroid hormone receptor 0.0021 0.0097 0.0315
Schistosoma mansoni glucose transporter 0.0028 0.0163 0.0163
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0045 0.0332 0.0554
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0021 0.0097 0.0097
Echinococcus multilocularis Two pore potassium channel protein sup 9 0.0023 0.0115 0.0115
Leishmania major hypothetical protein, conserved 0.0028 0.0163 0.0435
Mycobacterium ulcerans transmembrane cation transporter 0.0023 0.0115 0.0333
Loa Loa (eye worm) hypothetical protein 0.0238 0.2297 0.3787
Schistosoma mansoni serine/threonine protein kinase 0.0054 0.0425 0.0425
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0045 0.0332 0.1077
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 19. C. elegans unc-58 ortholog 0.0023 0.0115 0.0374
Loa Loa (eye worm) hypothetical protein 0.0016 0.0041 0.0068
Echinococcus granulosus serine:threonine protein kinase N2 0.0099 0.0879 0.0879
Loa Loa (eye worm) hypothetical protein 0.0044 0.0331 0.0546
Leishmania major glucose transporter/membrane transporter D2, putative 0.0061 0.0503 0.1557
Schistosoma mansoni loxhd1 0.0016 0.0041 0.0041
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 35 0.0023 0.0115 0.0374
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0085 0.0142
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0021 0.0093 0.0093
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0021 0.0093 0.0303
Trypanosoma cruzi cytochrome P450, putative 0.0015 0.0031 0.01
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0059 0.0483 0.0483
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0035 0.023 0.0225
Schistosoma mansoni coup transcription factor 0.0021 0.0097 0.0097
Echinococcus granulosus small conductance calcium activated potassium 0.061 0.6066 0.6066
Plasmodium vivax basic transcription factor 3b, putative 0.0026 0.0145 0.0123
Schistosoma mansoni cpg binding protein 0.0037 0.0252 0.0252
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0023 0.0115 0.0191
Trypanosoma cruzi cysteine peptidase, putative 0.0077 0.0661 0.2155
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0035 0.023 0.0751
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0093 0.0155
Trichomonas vaginalis sugar transporter, putative 0.0028 0.0163 0.0271
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0032 0.0203 0.0203
Echinococcus multilocularis potassium channel subfamily K 8 0.0023 0.0115 0.0115
Loa Loa (eye worm) hypothetical protein 0.0032 0.0204 0.0336
Trichomonas vaginalis sugar transporter, putative 0.0028 0.0163 0.0271
Loa Loa (eye worm) AGC/PKA protein kinase 0.0086 0.0753 0.1241
Giardia lamblia Low molecular weight protein-tyrosine-phosphatase 0.0264 0.2555 1
Echinococcus granulosus NDR protein kinase 0.0054 0.0425 0.0425
Trypanosoma cruzi transcription factor btf3, putative 0.0026 0.0145 0.0472
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0085 0.0142
Echinococcus granulosus Rac GTPase activating protein 1 0.0044 0.0331 0.0331
Leishmania major hypothetical protein, conserved 0.0023 0.0115 0.0277
Trichomonas vaginalis glucose transporter, putative 0.0061 0.0503 0.084
Loa Loa (eye worm) hypothetical protein 0.0185 0.1752 0.2889
Echinococcus granulosus cathepsin l cysteine peptidase 0.002 0.0085 0.0085
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 7 0.0023 0.0115 0.0374
Loa Loa (eye worm) phosphotyrosine protein phosphatase 0.0264 0.2555 0.4212
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0086 0.0753 0.0847
Trichomonas vaginalis sugar transporter, putative 0.0028 0.0163 0.0271
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0093 0.0155
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0035 0.0239 0.0239
Echinococcus granulosus Diacylglycerol kinase theta 0.0044 0.0331 0.0331
Mycobacterium leprae Probable lysyl-tRNA synthase LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0038 0.0261 0.1941
Brugia malayi nuclear hormone receptor 0.0021 0.0097 0.0315
Loa Loa (eye worm) hypothetical protein 0.0049 0.0374 0.0616
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0017 0.0057 0.0057
Trypanosoma cruzi hypothetical protein, conserved 0.0023 0.0115 0.0374
Brugia malayi lysyl-tRNA synthetase 0.0044 0.0329 0.1071
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0059 0.0483 0.1575
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0145 0.0242
Brugia malayi Hr1 repeat family protein 0.0054 0.0425 0.1385
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.0661 0.2149
Trypanosoma cruzi DNA polymerase kappa, putative 0.005 0.0383 0.1248
Schistosoma mansoni blooms syndrome DNA helicase 0.0032 0.0205 0.0205
Trichomonas vaginalis set domain proteins, putative 0.0276 0.2676 0.4464
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0063 0.052 0.0857
Trypanosoma brucei glucose transporter, putative 0.0061 0.0503 0.1635
Loa Loa (eye worm) hypothetical protein 0.0021 0.0097 0.0159
Loa Loa (eye worm) hypothetical protein 0.002 0.0085 0.014
Leishmania major cathepsin L-like protease 0.0077 0.0661 0.2076
Brugia malayi ubiquitin conjugating enzyme protein 13 0.0314 0.3068 1
Plasmodium falciparum protein kinase 6 0.0844 0.8437 1
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.008 0.0688 0.0688
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 28 0.0023 0.0115 0.0374
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0093 0.0155
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0264 0.2555 0.4262
Echinococcus multilocularis solute carrier family 22 0.0028 0.0163 0.0163
Onchocerca volvulus 0.0033 0.021 0.0726
Brugia malayi Pre-SET motif family protein 0.0242 0.2337 0.7619
Brugia malayi Cytochrome P450 family protein 0.0015 0.0031 0.01
Schistosoma mansoni protein kinase C 0.0049 0.0374 0.0374
Trypanosoma cruzi cytochrome P450, putative 0.0015 0.0031 0.01
Trichomonas vaginalis Sialidase-1 precursor, putative 0.0603 0.5994 1
Echinococcus multilocularis serine:threonine protein kinase 38 0.0054 0.0425 0.0425
Brugia malayi RhoGEF domain containing protein 0.0044 0.0331 0.1079
Schistosoma mansoni cathepsin F (C01 family) 0.002 0.0085 0.0085
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0093 0.0155
Trypanosoma cruzi DNA polymerase kappa, putative 0.005 0.0383 0.1248
Leishmania major lysyl-tRNA synthetase, putative 0.0044 0.0329 0.0982
Leishmania major DNA polymerase kappa, putative 0.0025 0.0138 0.0354
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0044 0.0329 0.1071
Brugia malayi Cathepsin L-like precursor 0.002 0.0085 0.0277
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0083 0.0263
Loa Loa (eye worm) hypothetical protein 0.0023 0.0115 0.0189
Loa Loa (eye worm) hypothetical protein 0.0016 0.0041 0.0068
Loa Loa (eye worm) hypothetical protein 0.0129 0.1185 0.1953
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0093 0.0818 0.2667
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.0661 0.2149
Brugia malayi Intermediate filament tail domain containing protein 0.0033 0.021 0.0685
Echinococcus multilocularis survival motor neuron protein 1 0.0286 0.2775 0.2775
Echinococcus multilocularis lipoxygenase domain containing protein 0.0016 0.0041 0.0041
Trypanosoma brucei DNA polymerase kappa, putative 0.005 0.0383 0.1241
Loa Loa (eye worm) cysteine protease 0.002 0.0085 0.014
Echinococcus multilocularis Sugar transporter ERD6 protein 0.0028 0.0163 0.0163
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0063 0.052 0.1694
Brugia malayi protein kinase C3,putative 0.0106 0.0953 0.3106
Onchocerca volvulus 0.0028 0.0163 0.0547
Echinococcus granulosus protein kinase c eta type 0.0044 0.0331 0.0331
Trypanosoma cruzi Enriched in surface-labeled proteome protein 12 0.0105 0.0944 0.3077
Plasmodium falciparum calcium-dependent protein kinase 5 0.0063 0.052 0.057
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0075 0.0639 0.0639
Schistosoma mansoni rac gtpase activating protein 0.0044 0.0331 0.0331
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0097 0.0097
Schistosoma mansoni serine/threonine protein kinase 0.0182 0.1721 0.1721
Trypanosoma cruzi sugar transporter, putative 0.0028 0.0163 0.053
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0017 0.0057 0.0094
Onchocerca volvulus 0.006 0.0486 0.1762
Giardia lamblia Hexose transporter 0.0028 0.0163 0.0284
Toxoplasma gondii ion channel protein 0.0023 0.0115 0.0181
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0085 0.0142
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0045 0.0332 1
Brugia malayi Protein kinase domain containing protein 0.0056 0.0453 0.1476
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0198 0.189 0.189
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 0.0314 0.3068 0.5058
Loa Loa (eye worm) hypothetical protein 0.0028 0.0163 0.0268
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0044 0.0331 0.0546
Loa Loa (eye worm) hypothetical protein 0.0023 0.0115 0.0189
Trypanosoma cruzi Enriched in surface-labeled proteome protein 12 0.0105 0.0944 0.3077
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0021 0.0093 0.0093
Loa Loa (eye worm) hypothetical protein 0.0014 0.0017 0.0028
Loa Loa (eye worm) hypothetical protein 0.0023 0.0115 0.0189
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0086 0.0753 0.2454
Echinococcus multilocularis N chimaerin 0.0044 0.0331 0.0331
Schistosoma mansoni protein kinase 0.0076 0.0653 0.0653
Brugia malayi diacylglycerol kinase 0.0044 0.0331 0.1079
Loa Loa (eye worm) hypothetical protein 0.0023 0.0115 0.0189
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0085 0.0142
Onchocerca volvulus 0.0028 0.0163 0.0547
Echinococcus granulosus intermediate filament protein 0.0033 0.021 0.021
Onchocerca volvulus Protein ultraspiracle homolog 0.0021 0.0097 0.0298
Brugia malayi Furin-like cysteine rich region family protein 0.01 0.0892 0.2906
Brugia malayi Ras association domain family 1 isoform A 0.0044 0.0331 0.1079
Loa Loa (eye worm) hypothetical protein 0.0229 0.2203 0.3633
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0093 0.0155
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0054 0.0424 0.0424
Brugia malayi Variant SH3 domain containing protein 0.0044 0.0331 0.1079
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0086 0.0753 0.2454
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 39B 0.0023 0.0115 0.0374
Loa Loa (eye worm) hypothetical protein 0.0021 0.0097 0.0159
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0198 0.189 0.189
Onchocerca volvulus 0.0028 0.0163 0.0547
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0069 0.0583 0.19
Onchocerca volvulus 0.0058 0.0471 0.1705
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0076 0.0653 0.0653
Loa Loa (eye worm) hypothetical protein 0.0079 0.0682 0.1125
Schistosoma mansoni hypothetical protein 0.0025 0.0138 0.0138
Echinococcus granulosus cpg binding protein 0.0037 0.0252 0.0252
Chlamydia trachomatis lysine--tRNA ligase 0.0044 0.0329 0.3249
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.008 0.0688 0.2243
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0045 0.0332 0.1083
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0086 0.0753 0.1327
Echinococcus granulosus protein kinase c epsilon type 0.0195 0.1855 0.1855
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0021 0.0097 0.0159
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0083 0.0263
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0051 0.0394 0.0394
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0097 0.0315
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0059 0.0483 0.1575
Echinococcus granulosus solute carrier family 22 0.0028 0.0163 0.0163
Toxoplasma gondii target of rapamycin (TOR), putative 0.0021 0.0093 0.0142
Loa Loa (eye worm) doublecortin family protein 0.0016 0.0041 0.0068
Trichomonas vaginalis AGC family protein kinase 0.0054 0.0425 0.0709
Loa Loa (eye worm) hypothetical protein 0.0044 0.0329 0.0542
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0045 0.0332 0.0554
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 30. 0.0023 0.0115 0.0374
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0453 0.0755
Schistosoma mansoni protein kinase 0.0063 0.052 0.052
Schistosoma mansoni hypothetical protein 0.0205 0.1955 0.1955
Schistosoma mansoni transcription factor btf3 0.0026 0.0145 0.0145
Brugia malayi Protein kinase domain containing protein 0.0054 0.0425 0.1385
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0013 0.0016 0.0004
Loa Loa (eye worm) S-phase kinase-associated protein 1A 0.0023 0.0115 0.0189
Schistosoma mansoni hypothetical protein 0.0205 0.1955 0.1955
Echinococcus multilocularis tumor protein p63 0.0408 0.4017 0.4017
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 24 0.0023 0.0115 0.0374
Leishmania major cathepsin L-like protease 0.002 0.0085 0.0179
Echinococcus multilocularis solute carrier family 22 0.0028 0.0163 0.0163
Brugia malayi ImpB/MucB/SamB family protein 0.0017 0.0057 0.0186
Loa Loa (eye worm) hypothetical protein 0.0081 0.0706 0.1164
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0054 0.0425 0.0425
Loa Loa (eye worm) hypothetical protein 0.0018 0.0059 0.0097
Trypanosoma brucei glucose transporter, putative 0.0061 0.0503 0.1635
Brugia malayi C1-like domain containing protein 0.0132 0.122 0.3975
Mycobacterium tuberculosis Possible transmembrane cation transporter 0.0023 0.0115 0.0202
Plasmodium falciparum calcium-dependent protein kinase 4 0.0063 0.052 0.057
Entamoeba histolytica cysteine proteinase, putative 0.0014 0.0017 0.0056
Brugia malayi Pleckstrin Homology Domain 0.0047 0.0359 0.117
Trichomonas vaginalis sugar transporter, putative 0.0028 0.0163 0.0271
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0093 0.0155
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0086 0.0753 0.0753
Mycobacterium ulcerans sugar transporter 0.0028 0.0163 0.0523
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0093 0.0155
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0093 0.0155
Trypanosoma cruzi cysteine peptidase, putative 0.0077 0.0661 0.2155
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0038 0.0261 0.0714
Brugia malayi hypothetical protein 0.0113 0.1025 0.334
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0021 0.0097 0.0097
Trichomonas vaginalis conserved hypothetical protein 0.0061 0.0503 0.084
Mycobacterium tuberculosis Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter) 0.0028 0.0163 0.0369
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0093 0.0155
Trichomonas vaginalis myo-inositol transporter, putative 0.0028 0.0163 0.0271
Loa Loa (eye worm) major facilitator superfamily transporter 0.0028 0.0163 0.0268
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0021 0.0097 0.0097
Leishmania major protein kinase A catalytic subunit 0.0086 0.0753 0.2378
Plasmodium vivax hexose transporter 0.0198 0.189 0.2202
Loa Loa (eye worm) hypothetical protein 0.0021 0.0097 0.0159
Schistosoma mansoni serine/threonine protein kinase 0.0182 0.1721 0.1721
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0029 0.0172 0.0172
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0063 0.052 0.0909
Echinococcus granulosus transcription factor Dp 1 0.0046 0.0348 0.0348
Trichomonas vaginalis AGC family protein kinase 0.0054 0.0425 0.0709
Leishmania major protein kinase, putative 0.0063 0.052 0.1611
Loa Loa (eye worm) hypothetical protein 0.0023 0.0115 0.0189
Onchocerca volvulus 0.002 0.0085 0.0255
Schistosoma mansoni calcium-activated potassium channel 0.061 0.6066 0.6066
Brugia malayi RhoGAP domain containing protein 0.0044 0.0331 0.1079
Echinococcus multilocularis Diacylglycerol kinase theta 0.0044 0.0331 0.0331
Trypanosoma cruzi calcium/potassium channel (CAKC), putative 0.0023 0.0115 0.0374
Entamoeba histolytica calcium-gated potassium channel protein, putative 0.0023 0.0115 0.0374
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.004 0.0285 0.2285
Trichomonas vaginalis sugar transporter, putative 0.0028 0.0163 0.0271
Onchocerca volvulus 0.0028 0.0163 0.0547
Echinococcus multilocularis cysteine protease 0.002 0.0085 0.0085
Loa Loa (eye worm) uncoordinated protein 58 0.0023 0.0115 0.0189
Loa Loa (eye worm) hypothetical protein 0.0028 0.0163 0.0268
Loa Loa (eye worm) hypothetical protein 0.0044 0.0331 0.0546
Entamoeba histolytica PH domain containing protein kinase, putative 0.0101 0.0907 0.2955
Loa Loa (eye worm) hypothetical protein 0.0035 0.0239 0.0394
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0045 0.0332 0.0572
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0021 0.0097 0.0159
Loa Loa (eye worm) hypothetical protein 0.0021 0.0097 0.0159
Loa Loa (eye worm) hypothetical protein 0.0021 0.0094 0.0155
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0021 0.0093 0.0093
Loa Loa (eye worm) hypothetical protein 0.0093 0.0818 0.1349
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0044 0.0329 0.1181
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0163 0.0271
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0054 0.0425 0.0425
Echinococcus multilocularis lysyl tRNA synthetase 0.0044 0.0329 0.0329
Leishmania major protein kinase A catalytic subunit isoform 1 0.0086 0.0753 0.2378
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0038 0.0262 0.0763
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0017 0.0057 0.0057
Loa Loa (eye worm) hypothetical protein 0.0113 0.1025 0.169
Schistosoma mansoni hypothetical protein 0.0016 0.0041 0.0041
Treponema pallidum prolyl-tRNA synthetase 0.0021 0.0093 1
Brugia malayi hypothetical protein 0.0016 0.0041 0.0134
Schistosoma mansoni diacylglycerol kinase theta 0.0044 0.0331 0.0331
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0097 0.0097
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.0661 0.2149
Echinococcus granulosus potassium channel subfamily K 8 0.0023 0.0115 0.0115
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0085 0.0142
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0093 0.0155
Loa Loa (eye worm) hypothetical protein 0.0023 0.0115 0.0189
Schistosoma mansoni sugar transporter 0.0028 0.0163 0.0163
Loa Loa (eye worm) hypothetical protein 0.0048 0.037 0.061
Echinococcus multilocularis lamin 0.0033 0.021 0.021
Echinococcus granulosus C2 calcium dependent membrane targeting 0.0049 0.0374 0.0374
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0027 0.0157 0.0511
Loa Loa (eye worm) hypothetical protein 0.0059 0.0483 0.0796
Plasmodium falciparum cysteine proteinase falcipain 3 0.002 0.0085 0.0052
Trypanosoma cruzi hexose transporter, putative 0.0061 0.0503 0.1641
Giardia lamblia Lysyl-tRNA synthetase 0.0044 0.0329 0.0958
Schistosoma mansoni serine/threonine kinase 0.0054 0.0425 0.0425
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0054 0.0425 0.07
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0086 0.0753 0.2454
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0323 0.3153 0.5635
Echinococcus multilocularis General substrate transporter 0.017 0.1608 0.1608
Schistosoma mansoni serine/threonine protein kinase 0.0045 0.0337 0.0337
Schistosoma mansoni tyrosine kinase 0.0032 0.0203 0.0203
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0097 0.0097
Echinococcus multilocularis calcium activated potassium channel variant 0.0023 0.0115 0.0115
Loa Loa (eye worm) ICD-1 protein 0.0026 0.0145 0.0239
Brugia malayi Doublecortin family protein 0.0016 0.0041 0.0134
Echinococcus multilocularis Polycystic kidney disease protein 0.0016 0.0041 0.0041
Loa Loa (eye worm) hypothetical protein 0.0023 0.0115 0.0189
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0034 0.0227 0.0227
Trichomonas vaginalis sugar transporter, putative 0.0061 0.0503 0.084
Leishmania major cathepsin L-like protease 0.002 0.0085 0.0179
Loa Loa (eye worm) hypothetical protein 0.0028 0.0163 0.0268
Loa Loa (eye worm) hypothetical protein 0.0025 0.0131 0.0217
Schistosoma mansoni terminal deoxycytidyl transferase 0.0017 0.0057 0.0057
Trichomonas vaginalis sugar transporter, putative 0.0028 0.0163 0.0271
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.0038 0.0261 0.0714
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0044 0.0329 0.0548
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0044 0.0329 0.1181
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0012 0.0002 0.0002
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0063 0.052 0.052
Entamoeba histolytica hypothetical protein 0.0029 0.0172 0.0562
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0063 0.052 0.052
Echinococcus multilocularis twik family of potassium channels 0.0023 0.0115 0.0115
Loa Loa (eye worm) hypothetical protein 0.0044 0.0331 0.0546
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0095 0.0845 0.0845
Mycobacterium tuberculosis Probable conserved integral membrane transport protein 0.0028 0.0163 0.0369
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.003 0.018 0.0166
Brugia malayi polk-prov protein 0.0038 0.0261 0.0849
Entamoeba histolytica protein kinase, putative 0.0054 0.0425 0.1385
Onchocerca volvulus 0.0028 0.0163 0.0547
Trypanosoma cruzi transcription factor btf3, putative 0.0026 0.0145 0.0472
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.0314 0.3068 1
Brugia malayi Cam kinase protein 1 0.0063 0.052 0.1694
Mycobacterium ulcerans prolyl-tRNA synthetase 0.0021 0.0093 0.0247
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0047 0.0352 0.037
Entamoeba histolytica cysteine protease, putative 0.002 0.0085 0.0277
Trichomonas vaginalis sugar transporter, putative 0.0028 0.0163 0.0271
Onchocerca volvulus 0.0028 0.0163 0.0547
Leishmania major calcium/potassium channel (CAKC), putative 0.0023 0.0115 0.0277
Echinococcus multilocularis lipoxygenase domain containing protein 0.0016 0.0041 0.0041
Onchocerca volvulus 0.0033 0.021 0.0726
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.0661 0.2149
Brugia malayi hypothetical protein 0.0023 0.0115 0.0374
Loa Loa (eye worm) papain family cysteine protease containing protein 0.002 0.0085 0.014
Schistosoma mansoni lysyl-tRNA synthetase 0.0044 0.0329 0.0329
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0058 0.0471 0.1534
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.008 0.0688 0.0688
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0054 0.0425 0.07
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.009 0.0788 0.1298
Echinococcus granulosus dna polymerase eta 0.0017 0.0057 0.0057
Echinococcus multilocularis raf serine:threonine protein kinase 0.0045 0.0337 0.0337
Brugia malayi Cathepsin L-like precursor 0.0014 0.0017 0.0056
Entamoeba histolytica protein kinase, putative 0.0063 0.052 0.1694
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0014 0.0017 0.0029
Echinococcus multilocularis bloom syndrome protein 0.005 0.0384 0.0384
Loa Loa (eye worm) hypothetical protein 0.0214 0.2047 0.3374
Echinococcus granulosus serine:threonine protein kinase N2 0.0054 0.0425 0.0425
Onchocerca volvulus 0.0276 0.2676 1
Trypanosoma cruzi ion transport protein, putative 0.0023 0.0115 0.0374
Schistosoma mansoni sugar transporter 0.0028 0.0163 0.0163
Echinococcus granulosus solute carrier family 22 0.0028 0.0163 0.0163
Trypanosoma cruzi major cysteine proteinase, putative 0.0061 0.0494 0.161
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0163 0.0271
Mycobacterium ulcerans DNA polymerase IV 0.005 0.0383 0.1395
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.0661 0.2149
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0086 0.0753 0.0847
Brugia malayi p70 ribosomal S6 kinase beta 0.0054 0.0425 0.1385
Echinococcus granulosus General substrate transporter 0.017 0.1608 0.1608
Schistosoma mansoni hypothetical protein 0.0494 0.4888 0.4888
Onchocerca volvulus Cathepsin F homolog 0.002 0.0085 0.0255
Plasmodium vivax calcium-dependent protein kinase, putative 0.0063 0.052 0.057
Loa Loa (eye worm) hypothetical protein 0.0028 0.0163 0.0268
Echinococcus granulosus neuropeptide receptor A26 0.0558 0.5542 0.5542
Echinococcus granulosus survival motor neuron protein 1 0.0286 0.2775 0.2775
Loa Loa (eye worm) hypothetical protein 0.0185 0.1752 0.2889
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0035 0.0239 0.0239
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0085 0.0142
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0085 0.0142
Leishmania major glucose transporter, lmgt2 0.0061 0.0503 0.1557
Echinococcus granulosus epidermal growth factor receptor 0.0054 0.0424 0.0424
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0453 0.0755
Echinococcus multilocularis protein kinase c eta type 0.0044 0.0331 0.0331
Loa Loa (eye worm) TWK-28 protein 0.0023 0.0115 0.0189
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0035 0.0239 0.0404
Echinococcus granulosus solute carrier family 22 0.0028 0.0163 0.0163
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.008 0.0688 0.2243
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0034 0.0227 0.0227
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0021 0.0093 0.0303
Brugia malayi hypothetical protein 0.0023 0.0115 0.0374
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.0661 0.2149
Loa Loa (eye worm) AGC/PKN protein kinase 0.0054 0.0425 0.07
Loa Loa (eye worm) large conductance calcium-activated potassium channel alpha subunit ai 0.0023 0.0115 0.0189
Plasmodium vivax vivapain-2 0.002 0.0085 0.0052
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 32 0.0023 0.0115 0.0374
Trypanosoma cruzi hexose transporter, putative 0.0034 0.0221 0.072
Loa Loa (eye worm) hypothetical protein 0.0023 0.0115 0.0189
Entamoeba histolytica protein kinase, putative 0.0056 0.0453 0.1476
Toxoplasma gondii AGC kinase 0.0054 0.0425 0.0738
Loa Loa (eye worm) hypothetical protein 0.0028 0.0163 0.0268
Trypanosoma cruzi PAB1-binding protein , putative 0.0018 0.0059 0.0191
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0063 0.052 0.0857
Schistosoma mansoni atypical protein kinase C 0.0157 0.1476 0.1476
Trypanosoma brucei DNA polymerase kappa, putative 0.0025 0.0138 0.0443
Loa Loa (eye worm) hypothetical protein 0.0126 0.1157 0.1907
Loa Loa (eye worm) hypothetical protein 0.0021 0.0097 0.0159
Echinococcus granulosus lysyl tRNA synthetase 0.0044 0.0329 0.0329
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.0661 0.2149
Echinococcus granulosus N chimaerin 0.0044 0.0331 0.0331
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0059 0.0483 0.0806
Mycobacterium tuberculosis Probable enoyl-CoA hydratase EchA14 (enoyl hydrase) (unsaturated acyl-CoA hydratase) (crotonase) 0.0299 0.2912 1
Brugia malayi Ubiquitin conjugating enzyme protein 13 0.0314 0.3068 1
Brugia malayi Steroid receptor seven-up type 2 0.0021 0.0097 0.0315
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0054 0.0425 0.0425
Trichomonas vaginalis sugar transporter, putative 0.0028 0.0163 0.0271
Echinococcus granulosus lipoxygenase domain containing protein 0.0016 0.0041 0.0041
Trichomonas vaginalis AGC family protein kinase 0.0054 0.0425 0.0709
Trypanosoma brucei DNA polymerase IV, putative 0.0042 0.0302 0.0978
Trypanosoma cruzi calcium/potassium channel (CAKC), putative 0.0023 0.0115 0.0374
Echinococcus multilocularis potassium channel subfamily K 8 0.0023 0.0115 0.0115
Mycobacterium ulcerans sugar phosphate isomerases/epimerases 0.0024 0.0127 0.0381
Loa Loa (eye worm) hypothetical protein 0.0014 0.0017 0.0028
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0086 0.0753 0.0753
Echinococcus granulosus geminin 0.0205 0.1955 0.1955
Schistosoma mansoni DNA helicase recq5 0.0035 0.023 0.023
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0021 0.0093 0.0303
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0035 0.023 0.0389
Schistosoma mansoni calcium-activated potassium channel 0.0023 0.0115 0.0115
Loa Loa (eye worm) hypothetical protein 0.0286 0.2775 0.4576
Echinococcus multilocularis twik family of potassium channels 0.0023 0.0115 0.0115
Plasmodium falciparum mitogen-activated protein kinase 2 0.0323 0.3153 0.3706
Loa Loa (eye worm) hypothetical protein 0.0023 0.0115 0.0189
Loa Loa (eye worm) hypothetical protein 0.0063 0.052 0.0857
Mycobacterium tuberculosis Conserved hypothetical protein 0.0024 0.0127 0.0244
Entamoeba histolytica recQ family DNA helicase 0.0018 0.0059 0.0191
Schistosoma mansoni RAR-like nuclear receptor 0.0021 0.0097 0.0097
Entamoeba histolytica protein kinase, putative 0.0067 0.0562 0.1833
Loa Loa (eye worm) hypothetical protein 0.0024 0.0127 0.0209
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0054 0.0425 0.07
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.0028 0.0163 0.0523
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0054 0.0425 0.07
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0093 0.0155
Echinococcus multilocularis epidermal growth factor receptor 0.01 0.0892 0.0892
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.0661 0.2149
Loa Loa (eye worm) hypothetical protein 0.0023 0.0115 0.0189
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 17 0.0023 0.0115 0.0374
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0021 0.0093 0.0296
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0021 0.0093 0.0303
Loa Loa (eye worm) hypothetical protein 0.0028 0.0163 0.0268
Loa Loa (eye worm) phosphatidylinositol 3 0.0021 0.0093 0.0153
Loa Loa (eye worm) hypothetical protein 0.0028 0.0163 0.0268
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0093 0.0155
Leishmania major hypothetical protein, conserved 0.0023 0.0115 0.0277
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.0661 0.2149
Loa Loa (eye worm) hypothetical protein 0.061 0.6066 1
Trichomonas vaginalis sugar transporter, putative 0.0061 0.0503 0.084
Brugia malayi Sugar transporter family protein 0.0028 0.0163 0.053
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0044 0.0329 0.1065
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0086 0.0753 0.2448
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0039 0.0273 0.0456
Brugia malayi cathepsin L-like precursor 0.0014 0.0017 0.0056
Toxoplasma gondii AGC kinase 0.0086 0.0753 0.1327
Onchocerca volvulus 0.002 0.0085 0.0255
Plasmodium falciparum potassium channel 0.0023 0.0115 0.0087
Trichomonas vaginalis PIKK family atypical protein kinase 0.0013 0.0014 0.0023
Leishmania major DNA polymerase eta, putative 0.0017 0.0057 0.0088
Trichomonas vaginalis sugar transporter, putative 0.0028 0.0163 0.0271
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0021 0.0097 0.0097
Trypanosoma brucei glucose transporter, putative 0.0061 0.0503 0.1635
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0093 0.0818 0.2668
Echinococcus granulosus calcium activated potassium channel variant 0.0023 0.0115 0.0115
Echinococcus multilocularis FTZ F1 alpha 0.0021 0.0097 0.0097
Echinococcus multilocularis small conductance calcium activated potassium 0.061 0.6066 0.6066
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0085 0.0142
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0198 0.189 0.189
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0198 0.189 0.189
Brugia malayi Cathepsin L-like precursor 0.002 0.0085 0.0277
Echinococcus granulosus raf serine:threonine protein kinase 0.0045 0.0337 0.0337
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0023 0.0115 0.0191
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0034 0.0227 0.0227
Trypanosoma brucei glucose transporter, putative 0.0061 0.0503 0.1635
Giardia lamblia DINP protein human, muc B family 0.0025 0.0138 0.0183
Trypanosoma cruzi cysteine peptidase, putative 0.002 0.0085 0.0277
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0076 0.0653 0.0653
Leishmania major glucose transporter, lmgt1 0.0061 0.0503 0.1557
Giardia lamblia Sgs1 DNA helicase, putative 0.0035 0.023 0.0559
Trichomonas vaginalis sugar transporter, putative 0.0028 0.0163 0.0271
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0132 0.122 0.201
Brugia malayi Cytochrome P450 family protein 0.0015 0.0031 0.01
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0054 0.0425 0.0425
Echinococcus granulosus Protein kinase C brain isozyme 0.0182 0.1721 0.1721
Entamoeba histolytica ubiquitin-conjugating enzyme family protein 0.0314 0.3068 1
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0264 0.2555 0.8328
Trypanosoma brucei DNA polymerase IV, putative 0.005 0.0383 0.1241
Brugia malayi Major Facilitator Superfamily protein 0.0028 0.0163 0.053
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0063 0.052 0.052
Trichomonas vaginalis sugar transporter, putative 0.0028 0.0163 0.0271
Onchocerca volvulus 0.002 0.0085 0.0255
Trichomonas vaginalis sugar transporter, putative 0.0028 0.0163 0.0271
Echinococcus granulosus ubiquitin conjugating enzyme E2 N 0.0314 0.3068 0.3068
Loa Loa (eye worm) hypothetical protein 0.0124 0.1133 0.1869
Schistosoma mansoni protein kinase 0.0076 0.0653 0.0653
Leishmania major glucose transporter, lmgt3 0.0061 0.0503 0.1557
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 13 0.0023 0.0115 0.0374
Schistosoma mansoni hypothetical protein 0.0044 0.0331 0.0331
Trypanosoma brucei glucose transporter, putative 0.0061 0.0503 0.1635
Brugia malayi Cathepsin L-like precursor 0.002 0.0085 0.0277
Trypanosoma brucei DNA polymerase kappa, putative 0.005 0.0383 0.1241
Trichomonas vaginalis sugar transporter, putative 0.0028 0.0163 0.0271
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0017 0.0057 0.0094
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0264 0.2555 0.8328
Brugia malayi Cathepsin L-like precursor 0.002 0.0085 0.0277
Echinococcus granulosus histone lysine methyltransferase setb 0.0035 0.0239 0.0239
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0021 0.0093 0.0093
Loa Loa (eye worm) hypothetical protein 0.0023 0.0115 0.0189
Loa Loa (eye worm) RasGEF domain-containing protein 0.0044 0.0331 0.0546
Onchocerca volvulus 0.0028 0.0163 0.0547
Leishmania major cysteine peptidase A (CPA) 0.002 0.0085 0.0179
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0085 0.0142
Trypanosoma cruzi hexose transporter, putative 0.0061 0.0503 0.1641
Onchocerca volvulus 0.0035 0.0239 0.0834
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0097 0.0315
Loa Loa (eye worm) RecQ helicase 0.005 0.0384 0.0633
Trypanosoma brucei DNA polymerase kappa, putative 0.005 0.0383 0.1241
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0069 0.0583 0.1022
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0045 0.0332 0.0993
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0453 0.0755
Loa Loa (eye worm) AGC/PKA protein kinase 0.0086 0.0753 0.1241
Onchocerca volvulus 0.0023 0.0115 0.0367
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0045 0.0332 0.1195
Entamoeba histolytica PH domain containing protein kinase, putative 0.0089 0.0781 0.2544
Loa Loa (eye worm) hypothetical protein 0.0028 0.0163 0.0268
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0088 0.0768 0.1267
Onchocerca volvulus 0.0028 0.0163 0.0547
Entamoeba histolytica PH domain containing protein kinase, putative 0.0089 0.0781 0.2544
Brugia malayi diacylglycerol kinase 0.0044 0.0331 0.1079
Mycobacterium ulcerans ion transport protein 0.0023 0.0115 0.0333
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.0314 0.3068 1
Brugia malayi Protein kinase c protein 2 0.0134 0.1239 0.4037
Trypanosoma brucei DNA polymerase kappa, putative 0.005 0.0383 0.1241
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0034 0.0227 0.0227
Echinococcus multilocularis calcium dependent protein kinase 0.0057 0.0457 0.0457
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0034 0.0227 0.0738
Schistosoma mansoni DNA polymerase eta 0.0017 0.0057 0.0057
Brugia malayi Cathepsin L-like precursor 0.002 0.0085 0.0277
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0086 0.0753 0.0753
Plasmodium falciparum proline--tRNA ligase 0.0069 0.0583 0.0645
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.008 0.0688 0.1135
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0021 0.0093 0.0304
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0021 0.0093 0.0303
Schistosoma mansoni cathepsin F (C01 family) 0.002 0.0085 0.0085
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0021 0.0093 0.0303
Schistosoma mansoni serine/threonine protein kinase 0.0054 0.0425 0.0425
Schistosoma mansoni rab6-interacting 0.0016 0.0041 0.0041
Schistosoma mansoni tyrosine kinase 0.0053 0.0418 0.0418
Schistosoma mansoni serine/threonine protein kinase 0.0051 0.0394 0.0394
Leishmania major myo-inositol/proton symporter (MIT) 0.0028 0.0163 0.0435
Schistosoma mansoni serine/threonine protein kinase 0.0051 0.0394 0.0394
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0195 0.1855 0.3058
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0085 0.0142
Loa Loa (eye worm) hypothetical protein 0.0023 0.0115 0.0189
Trichomonas vaginalis sugar transporter, putative 0.0028 0.0163 0.0271
Echinococcus granulosus calcium dependent protein kinase 0.0057 0.0457 0.0457
Echinococcus multilocularis solute carrier family 22 0.0028 0.0163 0.0163
Onchocerca volvulus 0.0126 0.1157 0.4287
Schistosoma mansoni hypothetical protein 0.0023 0.0115 0.0115
Leishmania major cathepsin L-like protease 0.002 0.0085 0.0179
Loa Loa (eye worm) hypothetical protein 0.0023 0.0115 0.0189
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0021 0.0093 0.0296
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0163 0.0271
Onchocerca volvulus Putative hydroxypyruvate isomerase 0.0024 0.0127 0.0412
Echinococcus multilocularis transcription factor Dp 1 0.0046 0.0348 0.0348
Toxoplasma gondii endonuclease IV APN 0.0093 0.0818 0.1445
Echinococcus multilocularis dna polymerase eta 0.0017 0.0057 0.0057
Echinococcus multilocularis insulin receptor 0.0032 0.0203 0.0203
Loa Loa (eye worm) major facilitator superfamily transporter 0.0028 0.0163 0.0268
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0021 0.0097 0.0159
Trypanosoma brucei rac serine-threonine kinase, putative 0.0056 0.0453 0.147
Trypanosoma brucei hypothetical protein, conserved 0.0105 0.0944 0.3072
Echinococcus multilocularis myotubularin protein 13 0.0047 0.0359 0.0359
Trypanosoma cruzi DNA polymerase kappa, putative 0.005 0.0383 0.1248
Schistosoma mansoni rab6-interacting 0.0016 0.0041 0.0041
Loa Loa (eye worm) raf kinase 0.0044 0.0331 0.0546
Onchocerca volvulus 0.0049 0.0374 0.134
Trypanosoma brucei glucose transporter 1E 0.0061 0.0503 0.1635
Trichomonas vaginalis sugar transporter, putative 0.0028 0.0163 0.0271
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0021 0.0097 0.0298
Brugia malayi latrophilin 2 splice variant baaae 0.0025 0.0138 0.045
Echinococcus granulosus Polycystic kidney disease protein 0.0016 0.0041 0.0041
Trypanosoma brucei cytochrome P450, putative 0.0015 0.0031 0.0093
Loa Loa (eye worm) hypothetical protein 0.0028 0.0163 0.0268
Trichomonas vaginalis CAMK family protein kinase 0.0063 0.052 0.0867
Loa Loa (eye worm) bifunctional aminoacyl-tRNA synthetase 0.0024 0.0128 0.021
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0021 0.0093 0.0296
Onchocerca volvulus 0.0016 0.0041 0.0091
Loa Loa (eye worm) hypothetical protein 0.0023 0.0115 0.0189
Schistosoma mansoni inositol monophosphatase 0.0045 0.0332 0.0332
Schistosoma mansoni lamin 0.0033 0.021 0.021
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0021 0.0093 0.0093
Echinococcus granulosus dnaJ subfamily B 0.0494 0.4888 0.4888
Echinococcus multilocularis cathepsin l cysteine peptidase 0.002 0.0085 0.0085
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0093 0.0155
Loa Loa (eye worm) hypothetical protein 0.0023 0.0115 0.0189
Toxoplasma gondii histone lysine methyltransferase SET1 0.0067 0.0559 0.0979
Loa Loa (eye worm) ctsf protein 0.002 0.0085 0.014
Plasmodium vivax ATP-dependent DNA helicase Q1, putative 0.0017 0.0052 0.0013
Schistosoma mansoni twik family of potassium channels-related 0.0023 0.0115 0.0115
Echinococcus multilocularis musashi 0.0033 0.021 0.021
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.008 0.0688 0.2243
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0021 0.0097 0.0315
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0182 0.1721 0.1721
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.008 0.069 0.069
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0032 0.0203 0.0203
Schistosoma mansoni twik family of potassium channels-related 0.0023 0.0115 0.0115
Trichomonas vaginalis glucose transporter, putative 0.0061 0.0503 0.084
Plasmodium falciparum cysteine proteinase falcipain 2a 0.002 0.0085 0.0052
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0063 0.052 0.1688
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0453 0.0755
Brugia malayi Protein kinase domain containing protein 0.0032 0.0203 0.0662
Trichomonas vaginalis sugar transporter, putative 0.0028 0.0163 0.0271
Brugia malayi Pre-SET motif family protein 0.0035 0.0239 0.0779
Trypanosoma brucei glucose transporter 2A 0.0061 0.0503 0.1635
Trypanosoma brucei calcium-activated potassium channel, putative 0.0023 0.0115 0.0367
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0093 0.0155
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0314 0.3068 0.5118
Trypanosoma brucei calcium/potassium channel (CAKC), putative 0.0023 0.0115 0.0367
Echinococcus granulosus potassium channel subfamily K 0.0023 0.0115 0.0115
Brugia malayi Sugar transporter family protein 0.0198 0.189 0.6162
Brugia malayi major facilitator superfamily protein 0.0028 0.0163 0.053
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0021 0.0097 0.0159
Onchocerca volvulus 0.0028 0.0163 0.0547
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0021 0.0097 0.0315
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0063 0.052 0.052
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0093 0.0155
Echinococcus multilocularis cathepsin L cysteine protease 0.002 0.0085 0.0085
Echinococcus granulosus Two pore potassium channel protein sup 9 0.0023 0.0115 0.0115
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0021 0.0097 0.0315
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0093 0.0818 0.0926
Brugia malayi photoreceptor-specific nuclear receptor 0.0021 0.0097 0.0315
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0045 0.0332 0.1083
Brugia malayi hypothetical protein 0.0286 0.2775 0.9046
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0023 0.0115 0.0191
Trichomonas vaginalis sugar transporter, putative 0.0028 0.0163 0.0271
Brugia malayi ecdysteroid receptor 0.0021 0.0097 0.0315
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0063 0.052 0.0909
Onchocerca volvulus Cathepsin L homolog 0.002 0.0085 0.0255
Schistosoma mansoni protein kinase 0.0063 0.052 0.052
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.0661 0.2149
Plasmodium vivax sugar transporter, putative 0.0028 0.0163 0.0145
Trypanosoma cruzi calcium-activated potassium channel, putative 0.0023 0.0115 0.0374
Echinococcus granulosus lamin dm0 0.0033 0.021 0.021
Loa Loa (eye worm) hypothetical protein 0.0021 0.0097 0.0159
Schistosoma mansoni hypothetical protein 0.0215 0.2063 0.2063
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.008 0.0688 0.2243
Echinococcus granulosus cathepsin l1 0.0014 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0086 0.0753 0.1241
Loa Loa (eye worm) hypothetical protein 0.0023 0.0115 0.0189
Trichomonas vaginalis sugar transporter, putative 0.0028 0.0163 0.0271
Trichomonas vaginalis sugar transporter, putative 0.0028 0.0163 0.0271
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0093 0.0155
Echinococcus multilocularis 0.0031 0.0193 0.0193
Loa Loa (eye worm) hypothetical protein 0.0015 0.0033 0.0055
Schistosoma mansoni steroid hormone receptor ad4bp 0.0021 0.0097 0.0097
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0453 0.0755
Trichomonas vaginalis sugar transporter, putative 0.0028 0.0163 0.0271
Trichomonas vaginalis DNA helicase recq1, putative 0.005 0.0384 0.064
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0198 0.189 0.189
Loa Loa (eye worm) hypothetical protein 0.0038 0.0261 0.043
Loa Loa (eye worm) TK/INSR protein kinase 0.0032 0.0203 0.0335
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0086 0.0753 0.2454
Trypanosoma brucei glucose transporter, putative 0.0061 0.0503 0.1635
Echinococcus granulosus protein kinase C gamma type 0.0137 0.127 0.127
Trichomonas vaginalis low molecular weight protein-tyrosine-phosphatase, putative 0.0264 0.2555 0.4262
Trichomonas vaginalis sugar transporter, putative 0.0028 0.0163 0.0271
Brugia malayi Papain family cysteine protease containing protein 0.002 0.0085 0.0277
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0029 0.0174 0.0287
Trypanosoma cruzi Enriched in surface-labeled proteome protein 12 0.0105 0.0944 0.3077
Loa Loa (eye worm) hypothetical protein 0.0023 0.0115 0.0189
Schistosoma mansoni cathepsin F (C01 family) 0.0014 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0028 0.0163 0.0268
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0093 0.0155
Trichomonas vaginalis sugar transporter, putative 0.0028 0.0163 0.0271
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0021 0.0097 0.0097
Trypanosoma brucei hypothetical protein, conserved 0.0105 0.0944 0.3072
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0038 0.0262 0.0848
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0048 0.0362 0.0604
Trichomonas vaginalis sugar transporter, putative 0.0028 0.0163 0.0271
Trichomonas vaginalis sugar transporter, putative 0.0028 0.0163 0.0271
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0198 0.189 0.189
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0021 0.0093 0.0303
Schistosoma mansoni cpg binding protein 0.0035 0.0232 0.0232
Loa Loa (eye worm) Ras association domain family 1 isoform A 0.0044 0.0331 0.0546
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0035 0.023 0.0389
Toxoplasma gondii lysine-tRNA ligase 0.0044 0.0329 0.0565
Trichomonas vaginalis conserved hypothetical protein 0.0198 0.189 0.3154
Loa Loa (eye worm) hypothetical protein 0.0023 0.0115 0.0189
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0097 0.0315
Schistosoma mansoni ubiquitin conjugating enzyme 13 0.0314 0.3068 0.3068
Schistosoma mansoni protein kinase 0.0063 0.052 0.052
Plasmodium vivax vivapain-2 0.002 0.0085 0.0052
Onchocerca volvulus Putative transporter 0.0028 0.0163 0.0547
Plasmodium falciparum calcium-dependent protein kinase 2 0.0063 0.052 0.057
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0029 0.0172 0.0555
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0095 0.0845 0.0845
Entamoeba histolytica diacylglycerol kinase, putative 0.0044 0.0331 0.1079
Brugia malayi Cathepsin L-like precursor 0.002 0.0085 0.0277
Onchocerca volvulus 0.0028 0.0163 0.0547
Loa Loa (eye worm) hypothetical protein 0.0044 0.0331 0.0546
Plasmodium falciparum ataxin-2 like protein, putative 0.0018 0.0059 0.0021
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0059 0.0483 0.0483
Leishmania major ion transport protein-like protein 0.0023 0.0115 0.0277
Loa Loa (eye worm) hypothetical protein 0.0023 0.0115 0.0189
Trichomonas vaginalis sugar transport protein, putative 0.0028 0.0163 0.0271
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.008 0.0688 0.0688
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0018 0.0059 0.0081
Brugia malayi protein kinase C II. 0.0195 0.1855 0.6045
Trypanosoma cruzi DNA polymerase eta, putative 0.0017 0.0057 0.0186
Loa Loa (eye worm) cytochrome P450 family protein 0.0015 0.0031 0.005
Schistosoma mansoni hypothetical protein 0.0058 0.0471 0.0471
Loa Loa (eye worm) inositol-1 0.0045 0.0332 0.0548
Trypanosoma brucei DNA polymerase IV, putative 0.005 0.0383 0.1241
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0086 0.0753 0.0753
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0037 0.0258 0.084
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.011 0.0994 0.1639
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0021 0.0093 0.0296
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0083 0.0263
Onchocerca volvulus 0.0023 0.0115 0.0367
Echinococcus granulosus lamin 0.0033 0.021 0.021
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0035 0.0239 0.0239
Echinococcus multilocularis telomerase reverse transcriptase subunit 0.0079 0.0682 0.0682
Loa Loa (eye worm) hypothetical protein 0.0023 0.0115 0.0189
Echinococcus granulosus serine protein kinase ATM 0.0029 0.0172 0.0172
Loa Loa (eye worm) hypothetical protein 0.0044 0.0331 0.0546
Onchocerca volvulus 0.0185 0.1752 0.6527
Loa Loa (eye worm) hypothetical protein 0.0021 0.0097 0.0159
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.008 0.0688 0.2238
Loa Loa (eye worm) hypothetical protein 0.0033 0.021 0.0346
Toxoplasma gondii sugar transporter ST2 0.0028 0.0163 0.0267
Loa Loa (eye worm) hypothetical protein 0.0028 0.0163 0.0268
Entamoeba histolytica deoxycytidyl transferase, putative 0.0017 0.0057 0.0186
Loa Loa (eye worm) steroid hormone receptor 0.0021 0.0097 0.0159
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0453 0.0755
Loa Loa (eye worm) hypothetical protein 0.0044 0.0331 0.0546
Schistosoma mansoni blooms syndrome DNA helicase 0.0018 0.0059 0.0059
Echinococcus multilocularis lamin dm0 0.0033 0.021 0.021
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0063 0.052 0.052
Loa Loa (eye worm) hypothetical protein 0.0023 0.0115 0.0189
Loa Loa (eye worm) hypothetical protein 0.0023 0.0115 0.0189
Loa Loa (eye worm) hypothetical protein 0.0025 0.0138 0.0228
Onchocerca volvulus Bile acid receptor homolog 0.0021 0.0097 0.0298
Schistosoma mansoni twik family of potassium channels-related 0.0023 0.0115 0.0115
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0086 0.0753 0.0753
Trypanosoma cruzi glucose transporter, putative 0.0028 0.0163 0.053
Schistosoma mansoni serine/threonine protein kinase 0.0063 0.052 0.052
Toxoplasma gondii transporter, major facilitator family protein 0.0028 0.0163 0.0267
Schistosoma mansoni cpg binding protein 0.0037 0.0252 0.0252
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 39A 0.0023 0.0115 0.0374
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0093 0.0155
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0097 0.0315
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0085 0.0142
Trypanosoma cruzi hexose transporter 0.0061 0.0503 0.1641
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0037 0.0258 0.0425
Trypanosoma cruzi calcium-activated potassium channel, putative 0.0023 0.0115 0.0374
Plasmodium vivax lysine--tRNA ligase, putative 0.0044 0.0329 0.0342
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0044 0.0331 0.0331
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0021 0.0097 0.0097
Loa Loa (eye worm) hypothetical protein 0.0023 0.0115 0.0189
Echinococcus multilocularis TWiK family of potassium channels protein 7 0.0023 0.0115 0.0115
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0027 0.0157 0.0511
Trypanosoma cruzi DNA polymerase kappa, putative 0.005 0.0383 0.1248
Loa Loa (eye worm) sugar transporter 0.0028 0.0163 0.0268
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0021 0.0097 0.0097
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0021 0.0093 0.0205
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0069 0.0583 0.1819
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0085 0.0142
Trichomonas vaginalis AGC family protein kinase 0.0086 0.0753 0.1256
Loa Loa (eye worm) hypothetical protein 0.0047 0.0359 0.0592
Schistosoma mansoni calcium-activated potassium channel 0.0452 0.4461 0.4461
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0085 0.0142
Schistosoma mansoni tyrosine kinase 0.0032 0.0203 0.0203
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0163 0.0271
Echinococcus multilocularis thyroid hormone receptor alpha 0.0021 0.0097 0.0097
Schistosoma mansoni sugar transporter 0.0028 0.0163 0.0163
Entamoeba histolytica hypothetical protein 0.0026 0.0145 0.0472
Toxoplasma gondii sugar transporter ST1 0.0028 0.0163 0.0267
Leishmania major cathepsin L-like protease 0.002 0.0085 0.0179
Schistosoma mansoni tyrosine kinase 0.0053 0.0418 0.0418
Trichomonas vaginalis glucose transporter, putative 0.0028 0.0163 0.0271
Giardia lamblia Hypothetical protein 0.0023 0.0115 0.0089
Schistosoma mansoni lamin 0.0033 0.021 0.021
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0021 0.0097 0.0097
Giardia lamblia Kinase, AGC PKA 0.0086 0.0753 0.268
Schistosoma mansoni serine/threonine protein kinase 0.0086 0.0753 0.0753
Trichomonas vaginalis DNA helicase recq, putative 0.005 0.0384 0.064
Entamoeba histolytica protein kinase, putative 0.0054 0.0425 0.1385
Echinococcus multilocularis dnaJ subfamily B 0.0494 0.4888 0.4888

Activities

Activity type Activity value Assay description Source Reference
Activity (ADMET) 0 Cytotoxicity against human erythrocytes assessed as hemolytic activity at 500 uM ChEMBL. 17383187
MIC (functional) = 22 uM Antifungal activity against Candida albicans ATCC 10231 ChEMBL. 17383187
MIC (functional) = 22 uM Antifungal activity against Candida albicans ATCC 10231 ChEMBL. 17383187
MIC (functional) = 88 uM Antifungal activity against Cryptococcus neoformans ATCC 90112 ChEMBL. 17383187
MIC (functional) = 88 uM Antifungal activity against Cryptococcus neoformans ATCC 90112 ChEMBL. 17383187

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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