Detailed information for compound 436005

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 605.647 | Formula: C34H34F3N3O4
  • H donors: 1 H acceptors: 3 LogP: 6.38 Rotable bonds: 12
    Rule of 5 violations (Lipinski): 2
  • SMILES: CC(C[C@H](N1C(=O)[C@H]([C@H]1/C=C/c1ccccc1)N1C(=O)OC[C@@H]1c1ccccc1)C(=O)NCc1cccc(c1)C(F)(F)F)C
  • InChi: 1S/C34H34F3N3O4/c1-22(2)18-28(31(41)38-20-24-12-9-15-26(19-24)34(35,36)37)39-27(17-16-23-10-5-3-6-11-23)30(32(39)42)40-29(21-44-33(40)43)25-13-7-4-8-14-25/h3-17,19,22,27-30H,18,20-21H2,1-2H3,(H,38,41)/b17-16+/t27-,28+,29-,30+/m1/s1
  • InChiKey: LHKPORVJCBWXML-KBGXRLPSSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens arginine vasopressin receptor 1A Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma brucei DNA polymerase kappa, putative 0.0018 0.0088 0.0185
Loa Loa (eye worm) hypothetical protein 0.0007 0.0002 0.0011
Brugia malayi Pao retrotransposon peptidase family protein 0.0012 0.0043 0.03
Schistosoma mansoni retinoic acid receptor RXR 0.003 0.0183 0.0347
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0067 0.0478 0.0914
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0026 0.0152 0.069
Wolbachia endosymbiont of Brugia malayi ribonuclease HI 0.0145 0.109 1
Schistosoma mansoni neuropeptide receptor 0.0007 0.0003 0.0001
Brugia malayi Protein kinase domain containing protein 0.0008 0.0006 0.0041
Echinococcus multilocularis fibropellin Ia 0.0011 0.0037 0.0036
Onchocerca volvulus 0.0007 0.0003 0.0005
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0064 0.0448 0.0447
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0029 0.0177 0.122
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0037 0.0235 0.1581
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0011 0.0037 0.0067
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0007 0.0003 0.0015
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0007 0.0003 0.0019
Brugia malayi hypothetical protein 0.0014 0.0058 0.04
Echinococcus granulosus phd:f box containing protein 0.0013 0.0047 0.0089
Echinococcus multilocularis rhodopsin orphan GPCR 0.0007 0.0003 0.0002
Loa Loa (eye worm) Ras association domain family 1 isoform A 0.0007 0.0002 0.0011
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.003 0.0183 0.0182
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0027 0.0161 0.0723
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.003 0.0183 0.0182
Trypanosoma brucei DNA polymerase kappa, putative 0.0018 0.0088 0.0185
Echinococcus multilocularis G-protein coupled receptor, putative 0.0007 0.0003 0.0002
Echinococcus granulosus ribonuclease H1 0.0145 0.109 0.2092
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0007 0.0003 0.0019
Onchocerca volvulus 0.0007 0.0003 0.0005
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0012 0.0038 0.0037
Loa Loa (eye worm) hypothetical protein 0.0029 0.0177 0.122
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0064 0.0448 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0026 0.0152 0.0335
Mycobacterium tuberculosis Conserved protein 0.0029 0.0177 0.12
Brugia malayi nuclear receptor RXR 0.0016 0.0071 0.0492
Toxoplasma gondii PPIC-type PPIASE domain-containing protein 0.0008 0.0013 0.01
Schistosoma mansoni hypothetical protein 0.0011 0.0037 0.0067
Loa Loa (eye worm) hypothetical protein 0.0014 0.0058 0.0395
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0012 0.0038 0.0134
Brugia malayi Calcium binding EGF domain containing protein 0.0011 0.0037 0.0255
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0016 0.0071 0.0136
Schistosoma mansoni amine GPCR 0.0007 0.0003 0.0001
Schistosoma mansoni smad1 5 8 and 0.0013 0.0046 0.0084
Schistosoma mansoni opsin-like receptor 0.0007 0.0003 0.0001
Brugia malayi Nuclear hormone receptor family member nhr-49 0.003 0.0183 0.1263
Loa Loa (eye worm) hypothetical protein 0.0011 0.0037 0.025
Mycobacterium ulcerans lipase LipD 0.0029 0.0177 0.3818
Brugia malayi ImpB/MucB/SamB family protein 0.0042 0.0275 0.1899
Toxoplasma gondii hypothetical protein 0.0022 0.0119 0.1075
Loa Loa (eye worm) hypothetical protein 0.0011 0.0037 0.025
Echinococcus granulosus myotubularin protein 13 0.0009 0.0017 0.0032
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0012 0.0039 0.0071
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0027 0.0161 0.0432
Schistosoma mansoni ap endonuclease 0.0029 0.0176 0.0334
Loa Loa (eye worm) hypothetical protein 0.0016 0.0071 0.0488
Loa Loa (eye worm) hypothetical protein 0.0036 0.0227 0.1563
Echinococcus granulosus Nuclear hormone receptor HR96 0.0014 0.0058 0.011
Trichomonas vaginalis CAMK family protein kinase 0.0077 0.0554 0.3795
Brugia malayi Pao retrotransposon peptidase family protein 0.0012 0.0043 0.03
Echinococcus granulosus expressed protein 0.0028 0.0166 0.0318
Brugia malayi EGF-like domain containing protein 0.0011 0.0037 0.0255
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0029 0.0177 0.0336
Brugia malayi Cadherin domain containing protein 0.0011 0.0037 0.0255
Echinococcus multilocularis microtubule associated protein 2 0.0509 0.3957 0.3957
Brugia malayi Nuclear hormone receptor E75 0.0014 0.0058 0.04
Trypanosoma brucei ingi protein (ORF1) 0.0157 0.1187 0.2786
Trichomonas vaginalis CAMK family protein kinase 0.0077 0.0554 0.3795
Echinococcus granulosus tm gpcr rhodopsin 0.0007 0.0003 0.0004
Brugia malayi jmjC domain containing protein 0.0013 0.0047 0.0324
Echinococcus granulosus delta-like protein 1 0.0011 0.0037 0.007
Echinococcus granulosus neurogenic locus notch protein 0.0011 0.0037 0.007
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.003 0.0183 0.035
Trichomonas vaginalis CAMK family protein kinase 0.0077 0.0554 0.3795
Echinococcus multilocularis protein jagged 2 0.0011 0.0037 0.0036
Brugia malayi C1-like domain containing protein 0.0065 0.0457 0.3158
Giardia lamblia Reverse transcriptase/endonuclease, putative 0.0012 0.0043 0.0309
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0008 0.0006 0.0005
Entamoeba histolytica P-glycoprotein-1 0.0008 0.0008 0.0014
Schistosoma mansoni atypical protein kinase C 0.0008 0.0006 0.0007
Echinococcus granulosus Nuclear hormone receptor HR96 0.0014 0.0058 0.011
Echinococcus multilocularis neuropeptide s receptor 0.0346 0.2677 0.2676
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0029 0.0176 0.383
Loa Loa (eye worm) hypothetical protein 0.0014 0.0058 0.0395
Toxoplasma gondii peptidylprolyl isomerase 0.0027 0.0161 0.146
Loa Loa (eye worm) hypothetical protein 0.0036 0.0227 0.1563
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0007 0.0003 0.0004
Schistosoma mansoni terminal deoxycytidyl transferase 0.0026 0.0152 0.0287
Echinococcus multilocularis fat cadherin tumor suppressor 0.0011 0.0037 0.0036
Trichomonas vaginalis glucosylceramidase, putative 0.0125 0.0931 0.6415
Giardia lamblia DINP protein human, muc B family 0.0026 0.0152 0.1313
Brugia malayi N-terminal motif family protein 0.0133 0.0996 0.6878
Onchocerca volvulus Neurogenic locus notch homolog 0.0011 0.0037 0.0319
Onchocerca volvulus 0.0007 0.0003 0.0005
Schistosoma mansoni jumonji/arid domain-containing protein 0.0049 0.0333 0.0636
Loa Loa (eye worm) hypothetical protein 0.001 0.0026 0.0173
Loa Loa (eye worm) nuclear receptor NHR-67 0.0014 0.0058 0.0395
Loa Loa (eye worm) animal heme peroxidase 0.0036 0.0227 0.1563
Echinococcus multilocularis g-protein coupled receptor 0.0007 0.0003 0.0002
Echinococcus granulosus neurogenic locus notch protein 4 0.0011 0.0037 0.007
Trypanosoma brucei PAB1-binding protein , putative 0.0021 0.0108 0.0232
Echinococcus granulosus 7tm_1 domain containing protein 0.0007 0.0003 0.0004
Trichomonas vaginalis glucosylceramidase, putative 0.0125 0.0931 0.6415
Brugia malayi Protein kinase c protein 2 0.0008 0.0006 0.0041
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0007 0.0003 0.0002
Plasmodium vivax hypothetical protein, conserved 0.0029 0.0177 0.3853
Echinococcus multilocularis protein jagged 1 0.0011 0.0037 0.0036
Schistosoma mansoni opsin-like receptor 0.0007 0.0003 0.0001
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0008 0.0008 0.0007
Echinococcus granulosus neural cadherin 0.0011 0.0037 0.007
Echinococcus multilocularis fmrfamide receptor 0.0007 0.0003 0.0002
Trypanosoma brucei DNA polymerase kappa, putative 0.0018 0.0088 0.0185
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0007 0.0003 0.0001
Echinococcus multilocularis fmrfamide receptor 0.0007 0.0003 0.0002
Trypanosoma cruzi DNA polymerase kappa, putative 0.0026 0.0152 0.0678
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0007 0.0002 0.0011
Brugia malayi G protein-coupled receptor 0.0007 0.0003 0.0019
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0007 0.0003 0.0001
Loa Loa (eye worm) hypothetical protein 0.0007 0.0003 0.0015
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0042 0.0275 0.1892
Trypanosoma brucei DNA polymerase kappa, putative 0.0026 0.0152 0.0335
Schistosoma mansoni nuclear receptor 0.0014 0.0058 0.0107
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0024 0.0133 0.1204
Plasmodium falciparum JmjC domain-containing protein, putative 0.0013 0.0047 0.0893
Echinococcus granulosus GPCR family 2 0.0036 0.0233 0.0447
Brugia malayi Nuclear hormone receptor E75 0.0014 0.0058 0.04
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0016 0.0071 0.0133
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0009 0.0019 0.0018
Echinococcus granulosus thyroid hormone receptor alpha 0.0014 0.0058 0.011
Schistosoma mansoni Tr4/Tr2 (homologue) 0.003 0.0183 0.0347
Trichomonas vaginalis MYB72, putative 0.0037 0.0235 0.1581
Brugia malayi RNase H family protein 0.0145 0.109 0.7529
Trichomonas vaginalis rotamase, putative 0.0027 0.0161 0.1066
Brugia malayi steroid hormone receptor 0.003 0.0183 0.1263
Echinococcus granulosus rhodopsin orphan GPCR 0.0007 0.0003 0.0004
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0012 0.0038 0.0134
Echinococcus granulosus cpg binding protein 0.0022 0.0123 0.0234
Echinococcus granulosus biogenic amine 5HT receptor 0.0007 0.0003 0.0004
Brugia malayi GnHR receptor homolog 0.0007 0.0003 0.0019
Brugia malayi hypothetical protein 0.0016 0.0071 0.0492
Trichomonas vaginalis D-aminoacylase, putative 0.0029 0.0177 0.1179
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0064 0.0448 1
Loa Loa (eye worm) hypothetical protein 0.0007 0.0003 0.0015
Echinococcus granulosus nuclear receptor 2DBD gamma 0.003 0.0183 0.035
Schistosoma mansoni cpg binding protein 0.0022 0.0123 0.0231
Loa Loa (eye worm) raf kinase 0.0007 0.0002 0.0011
Giardia lamblia Reverse transcriptase/endonuclease 0.0012 0.0043 0.0309
Brugia malayi Isocitrate dehydrogenase 0.0012 0.0038 0.0263
Schistosoma mansoni jumonji domain containing protein 0.0013 0.0047 0.0086
Loa Loa (eye worm) hypothetical protein 0.0013 0.0047 0.0319
Loa Loa (eye worm) hypothetical protein 0.0011 0.0037 0.025
Loa Loa (eye worm) hypothetical protein 0.0007 0.0003 0.0015
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0013 0.0046 0.0084
Echinococcus granulosus rhodopsin orphan GPCR 0.0007 0.0003 0.0004
Brugia malayi nuclear receptor NHR-88 0.0014 0.0058 0.04
Trichomonas vaginalis reverse transcriptases, putative 0.0012 0.0043 0.0249
Schistosoma mansoni DNA polymerase eta 0.0042 0.0275 0.0524
Schistosoma mansoni nuclear receptor 0.0014 0.0058 0.0107
Schistosoma mansoni jumonji/arid domain-containing protein 0.0049 0.0333 0.0636
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0007 0.0003 0.0002
Echinococcus granulosus Alpha N acetylgalactosaminidase 0.0083 0.0603 0.1158
Schistosoma mansoni phosphoglucomutase 0.0145 0.109 0.209
Echinococcus multilocularis protein kinase c epsilon type 0.0008 0.0006 0.0005
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0012 0.0038 0.0146
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0067 0.0478 0.3302
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0007 0.0003 0.0002
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0029 0.0176 0.0796
Loa Loa (eye worm) nuclear hormone receptor 0.0014 0.0058 0.0395
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0008 0.0008 0.0007
Brugia malayi MH2 domain containing protein 0.0013 0.0046 0.0316
Loa Loa (eye worm) hypothetical protein 0.0122 0.0905 0.6248
Echinococcus granulosus hypothetical protein 0.0007 0.0003 0.0004
Schistosoma mansoni hypothetical protein 0.0011 0.0037 0.0067
Schistosoma mansoni nuclear receptor nhr-48 0.0014 0.0058 0.0107
Echinococcus multilocularis expressed protein 0.0028 0.0166 0.0166
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0083 0.0603 0.1155
Brugia malayi RE15519p 0.0007 0.0003 0.0019
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0064 0.0448 0.4039
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0056 0.0384 0.0734
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0058 0.0401 0.2767
Leishmania major DNA polymerase eta, putative 0.0042 0.0275 0.1278
Schistosoma mansoni smdr2 0.0008 0.0008 0.001
Onchocerca volvulus Peroxidase homolog 0.0036 0.0227 0.2066
Leishmania major hypothetical protein, conserved 0.0013 0.0047 0.0188
Trichomonas vaginalis C-MYB, putative 0.0037 0.0235 0.1581
Loa Loa (eye worm) hypothetical protein 0.0007 0.0003 0.0015
Entamoeba histolytica P-glycoprotein-2 0.0008 0.0008 0.0014
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0029 0.0176 0.1539
Trypanosoma brucei DNA polymerase IV, putative 0.0026 0.0152 0.0335
Trichomonas vaginalis CAMK family protein kinase 0.0077 0.0554 0.3795
Toxoplasma gondii melibiase subfamily protein 0.0083 0.0603 0.5528
Loa Loa (eye worm) hypothetical protein 0.0016 0.0071 0.0488
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.001 0.0026 0.0025
Schistosoma mansoni slit 0.0011 0.0037 0.0067
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0014 0.0058 0.04
Brugia malayi Ras association domain family 1 isoform A 0.0007 0.0002 0.0015
Schistosoma mansoni hypothetical protein 0.0079 0.0567 0.1085
Schistosoma mansoni multidrug resistance protein 0.0008 0.0008 0.001
Echinococcus multilocularis allatostatin A receptor 0.0007 0.0003 0.0002
Trypanosoma brucei ingi protein (ORF1) 0.0157 0.1187 0.2786
Echinococcus multilocularis protein kinase c eta type 0.0007 0.0002 0.0002
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0007 0.0003 0.0001
Loa Loa (eye worm) hypothetical protein 0.0007 0.0002 0.0011
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0013 0.0047 0.0087
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0012 0.0038 0.0072
Echinococcus granulosus dna polymerase kappa 0.0026 0.0152 0.029
Echinococcus granulosus tm gpcr rhodopsin 0.0007 0.0003 0.0004
Loa Loa (eye worm) hypothetical protein 0.0007 0.0002 0.0011
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0007 0.0003 0.0001
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0008 0.0008 0.0013
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0037 0.0235 0.1581
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0045 0.0303 0.0578
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0007 0.0003 0.0019
Brugia malayi Animal haem peroxidase family protein 0.0036 0.0227 0.1567
Brugia malayi RNase H family protein 0.0145 0.109 0.7529
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0007 0.0003 0.0001
Echinococcus multilocularis multidrug resistance protein 1 0.0008 0.0008 0.0007
Echinococcus multilocularis RNA directed DNA polymerase (reverse transcriptase) 0.0012 0.0043 0.0043
Loa Loa (eye worm) hypothetical protein 0.0014 0.0058 0.0395
Giardia lamblia Reverse transcriptase/endonuclease, putative 0.0012 0.0043 0.0309
Schistosoma mansoni smad1 5 8 and 0.0013 0.0046 0.0084
Onchocerca volvulus Slit protein homolog 0.0011 0.0037 0.0319
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0007 0.0003 0.0015
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0029 0.0176 0.0337
Brugia malayi protein kinase C II. 0.0008 0.0006 0.0041
Brugia malayi Pao retrotransposon peptidase family protein 0.0012 0.0043 0.03
Brugia malayi hypothetical protein 0.0007 0.0003 0.0019
Brugia malayi G-protein coupled receptor 0.0007 0.0003 0.0019
Trypanosoma brucei DNA polymerase kappa, putative 0.0026 0.0152 0.0335
Brugia malayi Dopamine receptor protein 1 0.0007 0.0003 0.0019
Echinococcus multilocularis Rac GTPase activating protein 1 0.0007 0.0002 0.0002
Trichomonas vaginalis glucosylceramidase, putative 0.0125 0.0931 0.6415
Onchocerca volvulus 0.0036 0.0227 0.2066
Brugia malayi Animal haem peroxidase family protein 0.0036 0.0227 0.1567
Schistosoma mansoni hypothetical protein 0.0036 0.0233 0.0444
Trypanosoma cruzi PAB1-binding protein , putative 0.0021 0.0108 0.0469
Schistosoma mansoni vav2 0.0009 0.0017 0.0029
Loa Loa (eye worm) hypothetical protein 0.003 0.0183 0.1259
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0013 0.0047 0.0086
Entamoeba histolytica P-glycoprotein-5 0.0008 0.0008 0.0014
Loa Loa (eye worm) hypothetical protein 0.0011 0.0037 0.025
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0037 0.0235 0.1581
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0067 0.0478 0.3299
Mycobacterium tuberculosis Probable hydrolase 0.0029 0.0177 0.12
Echinococcus multilocularis peroxidasin 0.0036 0.0227 0.0226
Brugia malayi Pre-SET motif family protein 0.001 0.0026 0.0177
Brugia malayi G-protein coupled receptor 0.0007 0.0003 0.0019
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0007 0.0003 0.0019
Toxoplasma gondii ribonuclease HI protein 0.0145 0.109 1
Echinococcus multilocularis neurogenic locus protein delta 0.0011 0.0037 0.0036
Schistosoma mansoni protein kinase 0.0012 0.0043 0.0079
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0007 0.0003 0.0019
Schistosoma mansoni hypothetical protein 0.0036 0.0233 0.0444
Leishmania major ribonuclease H1, putative 0.0145 0.109 0.5174
Echinococcus granulosus allatostatin A receptor 0.0007 0.0003 0.0004
Echinococcus granulosus protein jagged 2 0.0011 0.0037 0.007
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0009 0.0019 0.0036
Brugia malayi nuclear receptor RXR 0.0014 0.0058 0.04
Loa Loa (eye worm) nuclear factor I 0.0007 0.0001 0.0004
Loa Loa (eye worm) hypothetical protein 0.0007 0.0002 0.0011
Loa Loa (eye worm) hypothetical protein 0.0007 0.0003 0.0015
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.003 0.0183 0.1259
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0008 0.0006 0.0036
Schistosoma mansoni peptidase Clp (S14 family) 0.0064 0.0448 0.0856
Schistosoma mansoni hypothetical protein 0.0012 0.0043 0.0079
Schistosoma mansoni hypothetical protein 0.0007 0.0003 0.0001
Echinococcus granulosus TGF beta signal transducer SmadC 0.0013 0.0046 0.0087
Schistosoma mansoni laminin gamma-3 chain 0.0011 0.0037 0.0067
Loa Loa (eye worm) hypothetical protein 0.0007 0.0003 0.0015
Toxoplasma gondii Myb family DNA-binding domain-containing protein 0.0037 0.0236 0.2154
Schistosoma mansoni histamine h1 receptor 0.0007 0.0003 0.0001
Echinococcus granulosus fmrfamide receptor 0.0007 0.0003 0.0004
Brugia malayi Pao retrotransposon peptidase family protein 0.0012 0.0043 0.03
Brugia malayi beta-lactamase 0.0029 0.0177 0.1224
Schistosoma mansoni hypothetical protein 0.0011 0.0037 0.0067
Echinococcus multilocularis Alpha N acetylgalactosaminidase 0.0083 0.0603 0.0603
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0029 0.0177 0.12
Brugia malayi ImpB/MucB/SamB family protein 0.0026 0.0152 0.1048
Loa Loa (eye worm) hypothetical protein 0.0057 0.0397 0.2742
Brugia malayi CXXC zinc finger family protein 0.0021 0.0113 0.0782
Trichomonas vaginalis DNA polymerase eta, putative 0.0026 0.0152 0.1002
Brugia malayi hypothetical protein 0.0036 0.0227 0.1567
Echinococcus multilocularis RNA directed DNA polymerase (reverse transcriptase) 0.0012 0.0043 0.0043
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.003 0.0183 0.1259
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0027 0.0161 0.0357
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0012 0.0038 0.0066
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0067 0.0478 0.3299
Schistosoma mansoni phosphatidylserine receptor 0.0013 0.0047 0.0086
Echinococcus multilocularis muscleblind protein 1 0.0122 0.0905 0.0904
Plasmodium falciparum DNA repair protein REV1, putative 0.0008 0.001 0.0057
Trichomonas vaginalis glucosylceramidase, putative 0.019 0.1447 1
Echinococcus granulosus FTZ F1 alpha 0.003 0.0183 0.035
Brugia malayi hypothetical protein 0.0007 0.0003 0.0019
Echinococcus granulosus serotonin receptor 0.0007 0.0003 0.0004
Schistosoma mansoni biogenic amine receptor 0.0007 0.0003 0.0001
Echinococcus multilocularis ecdysone induced protein 78C 0.003 0.0183 0.0182
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.003 0.0183 0.0347
Schistosoma mansoni microtubule-associated protein tau 0.0509 0.3957 0.76
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0007 0.0003 0.0001
Loa Loa (eye worm) hypothetical protein 0.003 0.0183 0.1259
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.003 0.0183 0.1259
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0029 0.0177 0.12
Schistosoma mansoni notch 0.0011 0.0037 0.0067
Echinococcus multilocularis g protein coupled receptor 0.0007 0.0003 0.0002
Onchocerca volvulus Neuropeptide F receptor homolog 0.0007 0.0003 0.0005
Brugia malayi Pao retrotransposon peptidase family protein 0.0012 0.0043 0.03
Schistosoma mansoni thyroid hormone receptor 0.003 0.0183 0.0347
Schistosoma mansoni kinase 0.0039 0.0256 0.0488
Brugia malayi jmjC domain containing protein 0.0013 0.0047 0.0324
Onchocerca volvulus Ribonuclease H1 homolog 0.0145 0.109 1
Loa Loa (eye worm) hypothetical protein 0.0007 0.0003 0.0015
Echinococcus multilocularis rhodopsin orphan GPCR 0.0007 0.0003 0.0002
Brugia malayi Nuclear hormone receptor family member nhr-19 0.003 0.0183 0.1263
Loa Loa (eye worm) hypothetical protein 0.0007 0.0003 0.0015
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.003 0.0183 0.1259
Leishmania major DNA polymerase eta, putative 0.0024 0.0133 0.0601
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0064 0.0448 1
Loa Loa (eye worm) hypothetical protein 0.0011 0.0037 0.025
Trichomonas vaginalis MYB3r3, putative 0.0037 0.0235 0.1581
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0083 0.0603 0.1155
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0007 0.0003 0.0001
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0014 0.0058 0.0057
Loa Loa (eye worm) neuropeptide F receptor 0.0007 0.0003 0.0015
Brugia malayi hypothetical protein 0.0007 0.0003 0.0019
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0065 0.0457 0.3154
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0007 0.0002 0.0002
Brugia malayi Nuclear hormone receptor-like 1 0.0016 0.0071 0.0492
Schistosoma mansoni serine/threonine protein kinase 0.0008 0.0006 0.0007
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.019 0.1447 1
Loa Loa (eye worm) hypothetical protein 0.0011 0.0037 0.025
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0014 0.0058 0.0512
Trypanosoma cruzi hypothetical protein, conserved 0.0029 0.0177 0.08
Echinococcus granulosus protein kinase c epsilon type 0.0008 0.0006 0.001
Loa Loa (eye worm) hypothetical protein 0.0036 0.0227 0.1563
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0029 0.0176 0.0393
Schistosoma mansoni amine GPCR 0.0007 0.0003 0.0001
Schistosoma mansoni cpg binding protein 0.0022 0.0123 0.0231
Trichomonas vaginalis CAMK family protein kinase 0.0077 0.0554 0.3795
Loa Loa (eye worm) hypothetical protein 0.0016 0.0071 0.0488
Loa Loa (eye worm) hypothetical protein 0.0036 0.0227 0.1563
Plasmodium vivax DNA repair protein REV1, putative 0.0008 0.001 0.0057
Brugia malayi RhoGAP domain containing protein 0.0007 0.0002 0.0015
Brugia malayi Nuclear hormone receptor family member nhr-3 0.003 0.0183 0.1263
Trichomonas vaginalis pc-MYB2, putative 0.0037 0.0235 0.1581
Schistosoma mansoni hypothetical protein 0.0056 0.0386 0.0738
Echinococcus multilocularis notch 0.0011 0.0037 0.0036
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0029 0.0177 0.12
Echinococcus granulosus multidrug resistance protein 1 0.0008 0.0008 0.0013
Brugia malayi putative neuropeptide receptor 0.0007 0.0003 0.0019
Brugia malayi Variant SH3 domain containing protein 0.0007 0.0002 0.0015
Trypanosoma cruzi hypothetical protein, conserved 0.0029 0.0177 0.08
Loa Loa (eye worm) hypothetical protein 0.0007 0.0003 0.0015
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0029 0.0176 0.0176
Echinococcus multilocularis GPCR, family 2 0.0036 0.0233 0.0233
Echinococcus multilocularis jumonji domain containing 1A 0.0013 0.0047 0.0046
Echinococcus granulosus RNA directed DNA polymerase reverse transcriptase 0.0012 0.0043 0.0082
Loa Loa (eye worm) hypothetical protein 0.0115 0.0854 0.5899
Brugia malayi Nuclear hormone receptor family member nhr-31 0.003 0.0183 0.1263
Brugia malayi larval opioid receptor 0.0007 0.0003 0.0019
Brugia malayi jmjC domain containing protein 0.0013 0.0047 0.0324
Schistosoma mansoni alpha-1 adrenergic receptor 0.0007 0.0003 0.0001
Brugia malayi jmjC domain containing protein 0.0049 0.0333 0.2301
Brugia malayi Animal haem peroxidase family protein 0.0036 0.0227 0.1567
Mycobacterium tuberculosis Probable esterase LipL 0.0029 0.0177 0.12
Trypanosoma brucei DNA polymerase kappa, putative 0.0026 0.0152 0.0335
Brugia malayi Nuclear hormone receptor family member nhr-14 0.003 0.0183 0.1263
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0007 0.0003 0.0001
Loa Loa (eye worm) animal heme peroxidase 0.0036 0.0227 0.1563
Loa Loa (eye worm) hypothetical protein 0.0007 0.0003 0.0015
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0014 0.0058 0.0057
Echinococcus granulosus protein kinase c eta type 0.0007 0.0002 0.0003
Toxoplasma gondii isocitrate dehydrogenase 0.0012 0.0038 0.033
Schistosoma mansoni hypothetical protein 0.0012 0.0043 0.0079
Trypanosoma cruzi polo-like protein kinase, putative 0.0077 0.0554 0.2604
Loa Loa (eye worm) hypothetical protein 0.0011 0.0037 0.025
Echinococcus multilocularis rhodopsin orphan GPCR 0.0007 0.0003 0.0002
Schistosoma mansoni biogenic amine (5HT) receptor 0.0007 0.0003 0.0001
Schistosoma mansoni biogenic amine receptor 0.0007 0.0003 0.0001
Echinococcus multilocularis neurogenic locus notch protein 0.0011 0.0037 0.0036
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0012 0.0038 0.0066
Echinococcus granulosus neurogenic locus notch protein 0.0011 0.0037 0.007
Schistosoma mansoni neuropeptide receptor 0.012 0.0894 0.1714
Leishmania major DNA polymerase kappa, putative 0.0026 0.0152 0.069
Loa Loa (eye worm) hypothetical protein 0.0007 0.0003 0.0015
Onchocerca volvulus Chorion peroxidase homolog 0.0036 0.0227 0.2066
Echinococcus granulosus orexin receptor type 2 0.0007 0.0003 0.0004
Trypanosoma brucei DNA polymerase eta, putative 0.0042 0.0275 0.0627
Trypanosoma cruzi DNA polymerase kappa, putative 0.0026 0.0152 0.0678
Toxoplasma gondii histone lysine methyltransferase SET1 0.004 0.0265 0.2419
Brugia malayi MH2 domain containing protein 0.0185 0.1406 0.9715
Entamoeba histolytica hypothetical protein 0.0056 0.0386 0.1045
Loa Loa (eye worm) hypothetical protein 0.0007 0.0003 0.0015
Onchocerca volvulus 0.001 0.0026 0.0215
Toxoplasma gondii Alpha-galactosidase 0.0012 0.0039 0.034
Schistosoma mansoni hypothetical protein 0.0007 0.0003 0.0001
Onchocerca volvulus 0.0007 0.0003 0.0005
Echinococcus granulosus alpha 1A adrenergic receptor 0.0007 0.0003 0.0004
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0115 0.0854 0.5901
Mycobacterium leprae Probable lipase LipE 0.0029 0.0177 0.1768
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0012 0.0038 0.0037
Onchocerca volvulus Dual oxidase homolog 0.0036 0.0227 0.2066
Trypanosoma cruzi PAB1-binding protein , putative 0.0021 0.0108 0.0469
Echinococcus multilocularis g protein coupled receptor 0.0007 0.0003 0.0002
Loa Loa (eye worm) hypothetical protein 0.0007 0.0003 0.0015
Brugia malayi hypothetical protein 0.0021 0.0108 0.0746
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0008 0.0008 0.0007
Echinococcus multilocularis neuropeptide Y receptor 0.0007 0.0003 0.0002
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0016 0.0071 0.0133
Loa Loa (eye worm) hypothetical protein 0.0007 0.0003 0.0015
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0007 0.0003 0.0002
Echinococcus granulosus dna polymerase eta 0.0042 0.0275 0.0527
Giardia lamblia High cysteine protein 0.0011 0.0037 0.0249
Brugia malayi Serotonin receptor 0.0007 0.0003 0.0019
Echinococcus granulosus geminin 0.0667 0.5206 1
Brugia malayi Dopamine receptor protein 2 0.0007 0.0003 0.0019
Onchocerca volvulus 0.0007 0.0003 0.0005
Schistosoma mansoni hypothetical protein 0.0017 0.0077 0.0145
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0037 0.0237 0.159
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0008 0.0013 0.0015
Trichomonas vaginalis glucosylceramidase, putative 0.0125 0.0931 0.6415
Mycobacterium tuberculosis Conserved hypothetical protein 0.0026 0.0152 0.102
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0037 0.0235 0.1581
Trichomonas vaginalis CAMK family protein kinase 0.0038 0.0248 0.167
Loa Loa (eye worm) isocitrate dehydrogenase 0.0012 0.0038 0.0259
Loa Loa (eye worm) hypothetical protein 0.0007 0.0003 0.0015
Trichomonas vaginalis glucosylceramidase, putative 0.0125 0.0931 0.6415
Brugia malayi hypothetical protein 0.0012 0.0043 0.03
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0036 0.0233 0.0233
Echinococcus multilocularis lysine specific demethylase 6a 0.0013 0.0047 0.0046
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0011 0.0037 0.0255
Mycobacterium ulcerans DNA polymerase IV 0.0026 0.0152 0.3236
Brugia malayi Calcium binding EGF domain containing protein 0.0011 0.0037 0.0255
Loa Loa (eye worm) hypothetical protein 0.003 0.0183 0.1259
Brugia malayi EGF-like domain containing protein 0.0011 0.0037 0.0255
Brugia malayi AKH receptor 0.0007 0.0003 0.0019
Echinococcus granulosus neuropeptide Y receptor 0.0007 0.0003 0.0004
Loa Loa (eye worm) hypothetical protein 0.0014 0.0058 0.0395
Echinococcus multilocularis neural cadherin 0.0011 0.0037 0.0036
Echinococcus multilocularis N chimaerin 0.0007 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0007 0.0003 0.0015
Loa Loa (eye worm) hypothetical protein 0.0007 0.0003 0.0015
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0007 0.0003 0.0002
Trichomonas vaginalis glucosylceramidase, putative 0.019 0.1447 1
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0007 0.0003 0.0001
Onchocerca volvulus 0.0014 0.0058 0.0512
Echinococcus granulosus rhodopsin orphan GPCR 0.0007 0.0003 0.0004
Echinococcus granulosus lysine specific demethylase 6a 0.0013 0.0047 0.0089
Loa Loa (eye worm) hypothetical protein 0.0036 0.0227 0.1563
Loa Loa (eye worm) DR-78 0.0014 0.0058 0.0395
Brugia malayi Muscleblind-like protein 0.0122 0.0905 0.625
Brugia malayi Smad1 0.0013 0.0046 0.0316
Brugia malayi latrophilin 2 splice variant baaae 0.0079 0.0567 0.3916
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.001 0.0026 0.0215
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0027 0.0161 0.0734
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.001 0.0026 0.0045
Brugia malayi Calcium binding EGF domain containing protein 0.0011 0.0037 0.0255
Loa Loa (eye worm) hypothetical protein 0.0007 0.0003 0.0015
Echinococcus granulosus g protein coupled receptor 0.0007 0.0003 0.0004
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0014 0.0058 0.0057
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0014 0.0058 0.011
Loa Loa (eye worm) hypothetical protein 0.0007 0.0003 0.0015
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0009 0.0019 0.0035
Loa Loa (eye worm) hypothetical protein 0.0007 0.0003 0.0015
Loa Loa (eye worm) hypothetical protein 0.0011 0.0037 0.025
Toxoplasma gondii isocitrate dehydrogenase 0.0012 0.0038 0.033
Loa Loa (eye worm) hypothetical protein 0.0011 0.0037 0.025
Onchocerca volvulus 0.0007 0.0003 0.0005
Loa Loa (eye worm) hypothetical protein 0.0066 0.0469 0.3234
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.001 0.0026 0.0045
Leishmania major hypothetical protein, conserved 0.0021 0.0108 0.048
Giardia lamblia Ribonuclease H 0.0145 0.109 1
Mycobacterium ulcerans esterase/lipase LipP 0.0029 0.0177 0.3818
Loa Loa (eye worm) hypothetical protein 0.0036 0.0227 0.1563
Loa Loa (eye worm) hypothetical protein 0.0007 0.0003 0.0015
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0007 0.0003 0.0001
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0064 0.0448 0.4098
Trichomonas vaginalis alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative 0.0056 0.0384 0.2618
Echinococcus multilocularis cpg binding protein 0.0022 0.0123 0.0122
Schistosoma mansoni phosphoglucomutase 0.0145 0.109 0.209
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.003 0.0183 0.0347
Schistosoma mansoni hypothetical protein 0.0007 0.0003 0.0001
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0007 0.0003 0.0002
Echinococcus multilocularis protein kinase c iota type 0.0008 0.0006 0.0005
Brugia malayi Pao retrotransposon peptidase family protein 0.0012 0.0043 0.03
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0064 0.0448 1
Echinococcus multilocularis RNA directed DNA polymerase (reverse transcriptase) 0.0012 0.0043 0.0043
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0013 0.0047 0.0176
Echinococcus multilocularis neuropeptides capa receptor 0.0007 0.0003 0.0002
Echinococcus granulosus RNA directed DNA polymerase reverse transcriptase 0.0012 0.0043 0.0082
Echinococcus multilocularis unc 13 (munc13) 0.0007 0.0002 0.0002
Schistosoma mansoni cpg binding protein 0.0021 0.0113 0.0213
Loa Loa (eye worm) hypothetical protein 0.0007 0.0002 0.0011
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0007 0.0003 0.0015
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0064 0.0448 1
Brugia malayi Muscle positioning protein 4 0.0011 0.0037 0.0255
Brugia malayi nuclear receptor NHR-88 0.003 0.0183 0.1263
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0029 0.0176 0.1193
Entamoeba histolytica hypothetical protein 0.0056 0.0386 0.1045
Echinococcus multilocularis dna polymerase kappa 0.0026 0.0152 0.0151
Trichomonas vaginalis penicillin-binding protein, putative 0.0029 0.0177 0.1179
Echinococcus multilocularis rhodopsin orphan GPCR 0.0007 0.0003 0.0002
Brugia malayi hypothetical protein 0.0012 0.0043 0.03
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.003 0.0183 0.1259
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0007 0.0003 0.0002
Echinococcus granulosus 7TM GPCR rhodopsin 0.0007 0.0003 0.0004
Toxoplasma gondii EGF family domain-containing protein 0.0011 0.0037 0.0319
Brugia malayi serine/threonine-protein kinase plk-2 0.0077 0.0554 0.3827
Brugia malayi hypothetical protein 0.0013 0.0051 0.035
Loa Loa (eye worm) hypothetical protein 0.0007 0.0003 0.0015
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0014 0.0058 0.0057
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0029 0.0176 0.0806
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0036 0.0233 0.0447
Loa Loa (eye worm) hypothetical protein 0.0008 0.0008 0.0047
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.003 0.0183 0.035
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0133 0.0996 0.9134
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0083 0.0603 0.1155
Echinococcus multilocularis dnaJ subfamily B 0.0301 0.2324 0.2323
Loa Loa (eye worm) hypothetical protein 0.0011 0.0037 0.025
Giardia lamblia Reverse transcriptase/endonuclease, putative 0.0012 0.0043 0.0309
Brugia malayi Animal haem peroxidase family protein 0.0036 0.0227 0.1567
Onchocerca volvulus Protein ultraspiracle homolog 0.003 0.0183 0.1661
Loa Loa (eye worm) jmjC domain-containing protein 0.0013 0.0047 0.0319
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0007 0.0003 0.0001
Onchocerca volvulus 0.0029 0.0177 0.1609
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0077 0.0554 0.3824
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0012 0.0038 0.0069
Loa Loa (eye worm) hypothetical protein 0.0036 0.0227 0.1563
Trypanosoma cruzi DNA polymerase eta, putative 0.0042 0.0275 0.1268
Loa Loa (eye worm) melatonin receptor type 1A 0.0007 0.0003 0.0015
Brugia malayi MH1 domain containing protein 0.0007 0.0001 0.0009
Echinococcus granulosus dnaJ subfamily B 0.0301 0.2324 0.4463
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0029 0.0176 0.1213
Onchocerca volvulus 0.0012 0.0043 0.0378
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0012 0.0038 0.0216
Schistosoma mansoni smad 0.0013 0.0046 0.0084
Brugia malayi hypothetical protein 0.0007 0.0003 0.0019
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0026 0.0152 0.0287
Onchocerca volvulus 0.0007 0.0003 0.0005
Echinococcus granulosus nuclear receptor nhr 48 0.0014 0.0058 0.011
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0064 0.0448 0.4098
Brugia malayi EGF-like domain containing protein 0.0011 0.0037 0.0255
Brugia malayi hypothetical protein 0.0014 0.0058 0.04
Trypanosoma brucei Endonuclease-reverse transcriptase/Reverse transcriptase (RNA-dependent DNA polymerase), putative 0.0012 0.0043 0.0079
Trypanosoma brucei DNA polymerase kappa, putative 0.0026 0.0152 0.0335
Brugia malayi jmjC domain containing protein 0.0013 0.0047 0.0324
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0077 0.0554 0.1063
Mycobacterium ulcerans hypothetical protein 0.0029 0.0177 0.3818
Brugia malayi G protein-coupled receptor F59B2.13 0.0007 0.0003 0.0019
Loa Loa (eye worm) hypothetical protein 0.0057 0.0397 0.2742
Brugia malayi hypothetical protein 0.0007 0.0003 0.0019
Schistosoma mansoni phosphoglucomutase 0.0145 0.109 0.209
Brugia malayi EGF-like domain containing protein 0.0011 0.0037 0.0255
Loa Loa (eye worm) hypothetical protein 0.0007 0.0002 0.0011
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0007 0.0003 0.0001
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0067 0.0478 0.0917
Trypanosoma cruzi ribonuclease H1, putative 0.0145 0.109 0.5168
Loa Loa (eye worm) hypothetical protein 0.0079 0.0567 0.3913
Trichomonas vaginalis ap endonuclease, putative 0.0029 0.0176 0.1172
Loa Loa (eye worm) hypothetical protein 0.0036 0.0227 0.1563
Schistosoma mansoni amine GPCR 0.0007 0.0003 0.0001
Brugia malayi hypothetical protein 0.0007 0.0003 0.0019
Brugia malayi Nuclear hormone receptor-like 1 0.0016 0.0071 0.0492
Echinococcus granulosus multidrug resistance protein 1 0.0008 0.0008 0.0013
Loa Loa (eye worm) hypothetical protein 0.0029 0.0177 0.122
Schistosoma mansoni coup transcription factor 0.003 0.0183 0.0347
Trichomonas vaginalis penicillin-binding protein, putative 0.0029 0.0177 0.1179
Onchocerca volvulus 0.0007 0.0003 0.0005
Echinococcus multilocularis neuropeptide receptor 0.012 0.0894 0.0894
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.003 0.0183 0.035
Echinococcus multilocularis G protein coupled receptor 139 0.012 0.0894 0.0894
Echinococcus granulosus microtubule associated protein 2 0.0509 0.3957 0.7601
Brugia malayi notch-like transmembrane receptor 0.0011 0.0037 0.0255
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0007 0.0003 0.0001
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0029 0.0176 0.3795
Onchocerca volvulus 0.0007 0.0003 0.0005
Loa Loa (eye worm) hypothetical protein 0.0011 0.0037 0.025
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0056 0.0384 0.0734
Mycobacterium tuberculosis Probable lipase LipE 0.0029 0.0177 0.12
Mycobacterium ulcerans beta-lactamase 0.0029 0.0177 0.3818
Schistosoma mansoni serine/threonine protein kinase 0.0008 0.0006 0.0007
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0007 0.0003 0.0004
Trypanosoma brucei RNA helicase, putative 0.0544 0.4234 1
Echinococcus granulosus RNA directed DNA polymerase 0.0012 0.0043 0.0082
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0011 0.0037 0.0319
Schistosoma mansoni hypothetical protein 0.0544 0.4234 0.8132
Echinococcus multilocularis lysine specific demethylase 5A 0.0048 0.0324 0.0323
Plasmodium vivax SET domain protein, putative 0.001 0.0026 0.0411
Trichomonas vaginalis rotamase, putative 0.0028 0.0166 0.1102
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0007 0.0003 0.0001
Brugia malayi Steroid receptor seven-up type 2 0.003 0.0183 0.1263
Loa Loa (eye worm) hypothetical protein 0.0007 0.0003 0.0015
Echinococcus granulosus KRAB A domain containing protein 0.0012 0.0043 0.0082
Echinococcus multilocularis Glycoside hydrolase, family 27 0.0083 0.0603 0.0603
Brugia malayi neuropeptide F receptor 0.0007 0.0003 0.0019
Echinococcus granulosus neurogenic locus protein delta 0.0011 0.0037 0.007
Echinococcus granulosus muscleblind protein 0.0122 0.0905 0.1736
Loa Loa (eye worm) hypothetical protein 0.0011 0.0037 0.025
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0007 0.0003 0.0001
Schistosoma mansoni hypothetical protein 0.0667 0.5206 1
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0007 0.0003 0.0002
Echinococcus granulosus lysine specific demethylase 5A 0.0049 0.0333 0.0639
Brugia malayi hypothetical protein 0.0007 0.0003 0.0019
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0029 0.0176 0.1515
Loa Loa (eye worm) hypothetical protein 0.0011 0.0037 0.025
Echinococcus granulosus g-protein coupled receptor 0.0007 0.0003 0.0004
Echinococcus multilocularis orexin receptor type 2 0.0007 0.0003 0.0002
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0007 0.0003 0.0015
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.003 0.0183 0.1661
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0012 0.0038 0.0037
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.003 0.0183 0.0182
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0012 0.0038 0.0694
Loa Loa (eye worm) hypothetical protein 0.003 0.0183 0.1259
Trichomonas vaginalis set domain proteins, putative 0.0077 0.0551 0.3774
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0007 0.0003 0.0001
Brugia malayi RhoGEF domain containing protein 0.0007 0.0002 0.0015
Loa Loa (eye worm) hypothetical protein 0.0007 0.0003 0.0015
Brugia malayi Nuclear hormone receptor family member nhr-25 0.003 0.0183 0.1263
Trichomonas vaginalis MYB, putative 0.0037 0.0237 0.159
Echinococcus granulosus neuropeptide receptor A26 0.0346 0.2677 0.5141
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0056 0.0386 0.0741
Echinococcus granulosus somatostatin receptor 0.0007 0.0003 0.0004
Loa Loa (eye worm) MH2 domain-containing protein 0.0185 0.1406 0.9715
Echinococcus granulosus beta LACTamase domain containing family member 0.0029 0.0177 0.0339
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0007 0.0003 0.0002
Loa Loa (eye worm) hypothetical protein 0.0007 0.0003 0.0015
Schistosoma mansoni rotamase 0.0028 0.0166 0.0315
Echinococcus multilocularis JmjC domain containing protein 4 0.0013 0.0047 0.0046
Brugia malayi MH1 domain containing protein 0.0007 0.0001 0.0009
Loa Loa (eye worm) hypothetical protein 0.003 0.0183 0.1259
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0008 0.0008 0.0013
Brugia malayi Nuclear hormone receptor-like 1 0.003 0.0183 0.1263
Echinococcus granulosus Protein kinase C brain isozyme 0.0008 0.0006 0.001
Brugia malayi Latrophilin receptor protein 2 0.0036 0.0233 0.1613
Echinococcus multilocularis RNA directed DNA polymerase 0.0012 0.0043 0.0043
Trichomonas vaginalis CAMK family protein kinase 0.0038 0.0248 0.167
Echinococcus multilocularis neuropeptide Y receptor 0.0007 0.0003 0.0002
Brugia malayi Nuclear hormone receptor family member nhr-25 0.003 0.0183 0.1263
Brugia malayi Tachykinin-like peptides receptor 99D 0.0007 0.0003 0.0019
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.003 0.0183 0.0182
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0067 0.0478 0.0917
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0016 0.0071 0.0071
Schistosoma mansoni neuropeptide f receptor 76f 0.0007 0.0003 0.0001
Echinococcus granulosus sex peptide receptor 0.0007 0.0003 0.0004
Loa Loa (eye worm) hypothetical protein 0.0014 0.0058 0.0395
Onchocerca volvulus 0.0057 0.0397 0.3633
Schistosoma mansoni protein phosphatase 2C 0.0013 0.0047 0.0086
Onchocerca volvulus Serine\/threonine kinase homolog 0.0077 0.0554 0.5073
Trypanosoma brucei DNA polymerase kappa, putative 0.0026 0.0152 0.0335
Echinococcus multilocularis somatostatin receptor 0.0007 0.0003 0.0002
Loa Loa (eye worm) neuropeptide F receptor 0.0007 0.0003 0.0015
Schistosoma mansoni neuropeptide F-like receptor 0.0007 0.0003 0.0001
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0008 0.0006 0.0036
Trichomonas vaginalis ap endonuclease, putative 0.0029 0.0176 0.1172
Brugia malayi conserved hypotetical protein 0.0014 0.0058 0.04
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0014 0.0058 0.0512
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0026 0.0152 0.0151
Echinococcus granulosus rhodopsin orphan GPCR 0.0007 0.0003 0.0004
Loa Loa (eye worm) hypothetical protein 0.0007 0.0003 0.0015
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0013 0.0046 0.0045
Trypanosoma brucei DNA polymerase kappa, putative 0.0026 0.0152 0.0335
Echinococcus granulosus tachykinin peptides receptor 99D 0.0007 0.0003 0.0004
Echinococcus multilocularis neurogenic locus notch protein 4 0.0011 0.0037 0.0036
Loa Loa (eye worm) Notch2 0.0011 0.0037 0.025
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0008 0.001 0.0072
Trichomonas vaginalis reverse transcriptases, putative 0.0012 0.0043 0.0249
Schistosoma mansoni Smad4 0.0013 0.0046 0.0084
Trypanosoma brucei ribonuclease H1 0.0145 0.109 0.2556
Brugia malayi polk-prov protein 0.0008 0.001 0.0069
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0007 0.0003 0.0001
Echinococcus granulosus raf serine:threonine protein kinase 0.0007 0.0002 0.0003
Brugia malayi photoreceptor-specific nuclear receptor 0.003 0.0183 0.1263
Loa Loa (eye worm) TYRA-2 protein 0.0007 0.0003 0.0015
Schistosoma mansoni unc-13 (munc13) 0.0009 0.0013 0.0021
Brugia malayi MH1 domain containing protein 0.0013 0.0046 0.0316
Loa Loa (eye worm) hypothetical protein 0.0036 0.0227 0.1563
Schistosoma mansoni peroxidasin 0.0036 0.0227 0.0432
Loa Loa (eye worm) hypothetical protein 0.0007 0.0003 0.0015
Echinococcus multilocularis neuropeptide FF receptor 2 0.0007 0.0003 0.0002
Echinococcus granulosus neuropeptides capa receptor 0.0007 0.0003 0.0004
Loa Loa (eye worm) hypothetical protein 0.0016 0.0071 0.0488
Trypanosoma brucei DNA polymerase IV, putative 0.0026 0.0152 0.0335
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.003 0.0183 0.1263
Trypanosoma cruzi DNA polymerase kappa, putative 0.0026 0.0152 0.0678
Loa Loa (eye worm) hypothetical protein 0.0007 0.0003 0.0015
Schistosoma mansoni jumonji domain containing protein 0.0048 0.0324 0.0617
Schistosoma mansoni hypothetical protein 0.0007 0.0003 0.0001
Leishmania major hypothetical protein, conserved 0.0029 0.0177 0.0811
Brugia malayi Pao retrotransposon peptidase family protein 0.0012 0.0043 0.03
Brugia malayi Pleckstrin Homology Domain 0.0009 0.0017 0.012
Echinococcus granulosus protein jagged 1 0.0011 0.0037 0.007
Schistosoma mansoni multidrug resistance protein 0.0008 0.0008 0.001
Echinococcus multilocularis myotubularin protein 13 0.0009 0.0017 0.0017
Echinococcus multilocularis rhodopsin orphan GPCR 0.0007 0.0003 0.0002
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0007 0.0003 0.0004
Brugia malayi Pao retrotransposon peptidase family protein 0.0012 0.0043 0.03
Loa Loa (eye worm) hypothetical protein 0.0029 0.0177 0.122
Onchocerca volvulus Telomerase reverse transcriptase homolog 0.0012 0.0043 0.0378
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0083 0.0603 0.1155
Echinococcus multilocularis dro:myosuppressin receptor 0.0007 0.0003 0.0002
Brugia malayi orphan nuclear receptor NR2E1 0.0014 0.0058 0.04
Brugia malayi Pre-SET motif family protein 0.0067 0.0478 0.3302
Loa Loa (eye worm) hypothetical protein 0.0007 0.0002 0.0011
Loa Loa (eye worm) hypothetical protein 0.0064 0.0448 0.3092
Brugia malayi MH1 domain containing protein 0.0013 0.0046 0.0316
Brugia malayi diacylglycerol kinase 0.0007 0.0002 0.0015
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0007 0.0002 0.0011
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0029 0.0176 0.0796
Onchocerca volvulus 0.0007 0.0003 0.0005
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0029 0.0177 0.0336
Schistosoma mansoni biogenic amine (5HT) receptor 0.0007 0.0003 0.0001
Brugia malayi beta-lactamase family protein 0.0029 0.0177 0.1224
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.003 0.0183 0.0182
Loa Loa (eye worm) hypothetical protein 0.0007 0.0003 0.0015
Schistosoma mansoni cell polarity protein 0.0011 0.0037 0.0067
Brugia malayi Blistered cuticle protein 3 0.0036 0.0227 0.1567
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0028 0.0166 0.1148
Onchocerca volvulus 0.0007 0.0003 0.0005
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.003 0.0183 0.0347
Trypanosoma brucei hypothetical protein, conserved 0.0029 0.0177 0.0396
Loa Loa (eye worm) hypothetical protein 0.0007 0.0002 0.0011
Schistosoma mansoni serine/threonine protein kinase 0.0077 0.0554 0.106
Trichomonas vaginalis esterase, putative 0.0029 0.0177 0.1179
Loa Loa (eye worm) hypothetical protein 0.0007 0.0003 0.0015
Trichomonas vaginalis D-aminoacylase, putative 0.0029 0.0177 0.1179
Loa Loa (eye worm) hypothetical protein 0.0029 0.0177 0.122
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0014 0.0056 0.0107
Loa Loa (eye worm) hypothetical protein 0.003 0.0183 0.1259
Onchocerca volvulus 0.0064 0.0453 0.4148
Trichomonas vaginalis glucosylceramidase, putative 0.0125 0.0931 0.6415
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0027 0.0161 0.0723
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0077 0.0554 0.0553
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0007 0.0003 0.0002
Mycobacterium tuberculosis Conserved protein 0.0029 0.0177 0.12
Schistosoma mansoni opsin-like receptor 0.0007 0.0003 0.0001
Loa Loa (eye worm) latrophilin receptor protein 2 0.0036 0.0233 0.1609
Trypanosoma brucei unspecified product 0.0026 0.0152 0.0335
Schistosoma mansoni retinoid-x-receptor (RXR) 0.003 0.0183 0.0347
Echinococcus granulosus neuropeptide receptor 0.012 0.0894 0.1716
Schistosoma mansoni zinc finger protein 0.0014 0.0058 0.0107
Brugia malayi EGF-like domain containing protein 0.0011 0.0037 0.0255
Toxoplasma gondii ATP-binding cassette transporter ABC.B1 0.0008 0.0008 0.0049
Echinococcus granulosus RNA directed DNA polymerase reverse transcriptase 0.0012 0.0043 0.0082
Onchocerca volvulus 0.0011 0.0037 0.0319
Loa Loa (eye worm) hypothetical protein 0.0014 0.0058 0.0395
Loa Loa (eye worm) hypothetical protein 0.0036 0.0233 0.1609
Schistosoma mansoni scy1(yeast) protein kinase-like 0.0012 0.0043 0.0079
Echinococcus multilocularis RNA directed DNA polymerase (reverse transcriptase) 0.0012 0.0043 0.0043
Brugia malayi hypothetical protein 0.0007 0.0003 0.0019
Schistosoma mansoni hypothetical protein 0.0301 0.2324 0.4461
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0048 0.0324 0.0323
Loa Loa (eye worm) hypothetical protein 0.0008 0.0007 0.0043
Echinococcus multilocularis RNA directed DNA polymerase (reverse transcriptase) 0.0012 0.0043 0.0043
Echinococcus granulosus protein jagged 2 0.0011 0.0037 0.007
Schistosoma mansoni notch 0.0011 0.0037 0.0067
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.003 0.0183 0.1259
Trypanosoma brucei DNA polymerase IV, putative 0.0026 0.0152 0.0335
Echinococcus multilocularis muscleblind protein 0.0122 0.0905 0.0904
Trypanosoma brucei SLACS retrotransposable element (part), putative 0.0012 0.0043 0.0079
Plasmodium falciparum ataxin-2 like protein, putative 0.0021 0.0108 0.228
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0064 0.0448 0.0859
Loa Loa (eye worm) hypothetical protein 0.0014 0.0058 0.0395
Onchocerca volvulus Glucosylceramidase homolog 0.0125 0.0931 0.8542
Brugia malayi exodeoxyribonuclease III family protein 0.0029 0.0176 0.1217
Loa Loa (eye worm) hypothetical protein 0.0011 0.0037 0.025
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0067 0.0478 0.0914
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0056 0.0386 0.0386
Toxoplasma gondii ABC1 family protein 0.0029 0.0177 0.1609
Loa Loa (eye worm) hypothetical protein 0.0014 0.0058 0.0395
Trichomonas vaginalis glucosylceramidase, putative 0.019 0.1447 1
Loa Loa (eye worm) hypothetical protein 0.0029 0.0177 0.122
Echinococcus granulosus histone lysine methyltransferase setb 0.001 0.0026 0.0048
Loa Loa (eye worm) hypothetical protein 0.0036 0.0227 0.1563
Trypanosoma brucei unspecified product 0.0018 0.0088 0.0185
Brugia malayi Dopamine receptor 0.0007 0.0003 0.0019
Loa Loa (eye worm) hypothetical protein 0.003 0.0183 0.1259
Echinococcus granulosus peptidase Clp S14 family 0.0042 0.0275 0.0527
Loa Loa (eye worm) hypothetical protein 0.0007 0.0003 0.0015
Brugia malayi Nuclear hormone receptor family member nhr-19 0.003 0.0183 0.1263
Echinococcus multilocularis rhodopsin orphan GPCR 0.0007 0.0003 0.0002
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0013 0.0047 0.0176
Schistosoma mansoni hypothetical protein 0.0036 0.0233 0.0444
Loa Loa (eye worm) hypothetical protein 0.0007 0.0003 0.0015
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0008 0.0008 0.0013
Giardia lamblia Myb 1-like protein 0.0037 0.0236 0.2097
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0007 0.0003 0.0002
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0022 0.0119 0.2533
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0037 0.0235 0.1581
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0008 0.0008 0.0013
Echinococcus granulosus RNA directed DNA polymerase reverse transcriptase 0.0012 0.0043 0.0082
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0037 0.0235 0.1581
Echinococcus granulosus 5'partial|ATP binding cassette sub family B 0.0008 0.0007 0.0012
Echinococcus granulosus slit 2 protein 0.0011 0.0037 0.007
Loa Loa (eye worm) hypothetical protein 0.0011 0.0037 0.025
Onchocerca volvulus 0.0029 0.0177 0.1609
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.003 0.0183 0.035
Brugia malayi follicle stimulating hormone receptor 0.0007 0.0003 0.0019
Schistosoma mansoni nuclear hormone receptor 0.0014 0.0058 0.0107
Trypanosoma brucei squalene monooxygenase, putative 0.0273 0.2099 0.4945
Brugia malayi nuclear hormone receptor family member nhr-6 0.0014 0.0058 0.04
Onchocerca volvulus Bile acid receptor homolog 0.003 0.0183 0.1661
Plasmodium vivax JmjC domain containing protein 0.0013 0.0047 0.0893
Schistosoma mansoni adenoreceptor 0.0007 0.0003 0.0001
Loa Loa (eye worm) MH1 domain-containing protein 0.0013 0.0046 0.0311
Onchocerca volvulus Putative cubilin 0.0011 0.0037 0.0319
Loa Loa (eye worm) hypothetical protein 0.0007 0.0003 0.0015
Schistosoma mansoni amine GPCR 0.0007 0.0003 0.0001
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0077 0.0554 0.2612
Brugia malayi hypothetical protein 0.0012 0.0043 0.03
Entamoeba histolytica deoxycytidyl transferase, putative 0.0026 0.0152 0.0407
Trichomonas vaginalis CAMK family protein kinase 0.0077 0.0554 0.3795
Schistosoma mansoni neuropeptide receptor 0.0007 0.0003 0.0001
Schistosoma mansoni serine/threonine protein kinase 0.0008 0.0006 0.0007
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0007 0.0003 0.0001
Schistosoma mansoni hypothetical protein 0.0011 0.0037 0.0067
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0013 0.0047 0.041
Brugia malayi sulfakinin receptor protein 0.0007 0.0003 0.0019
Brugia malayi Nuclear hormone receptor family member nhr-41 0.003 0.0183 0.1263
Echinococcus multilocularis rhodopsin orphan GPCR 0.0007 0.0003 0.0002
Brugia malayi beta-lactamase family protein 0.0029 0.0177 0.1224
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0008 0.0008 0.0049
Brugia malayi ecdysone receptor 0.0014 0.0058 0.04
Echinococcus multilocularis ribonuclease H1 0.0145 0.109 0.1089
Schistosoma mansoni serine/threonine protein kinase 0.0008 0.0006 0.0007
Brugia malayi hypothetical protein 0.0016 0.0071 0.0492
Entamoeba histolytica hypothetical protein 0.0056 0.0386 0.1045
Loa Loa (eye worm) hypothetical protein 0.0014 0.0058 0.0395
Schistosoma mansoni notch 0.0011 0.0037 0.0067
Loa Loa (eye worm) steroid hormone receptor 0.003 0.0183 0.1259
Brugia malayi Peroxidasin 0.0036 0.0227 0.1567
Echinococcus multilocularis RNA directed DNA polymerase (reverse transcriptase) 0.0012 0.0043 0.0043
Loa Loa (eye worm) blistered cuticle protein 3 0.0036 0.0227 0.1563
Treponema pallidum ribonuclease H (rnhA) 0.0145 0.109 1
Loa Loa (eye worm) hypothetical protein 0.0008 0.001 0.0065
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0012 0.0038 0.0037
Trypanosoma cruzi polo-like protein kinase, putative 0.0077 0.0554 0.2604
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.0037 0.0235 0.0634
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0007 0.0003 0.0002
Schistosoma mansoni notch 0.0011 0.0037 0.0067
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0065 0.0457 0.3158
Echinococcus multilocularis phd:f box containing protein 0.0013 0.0047 0.0046
Echinococcus multilocularis rhodopsin orphan GPCR 0.0007 0.0003 0.0002
Entamoeba histolytica hypothetical protein, conserved 0.0473 0.3676 1
Brugia malayi Zinc knuckle family protein 0.0012 0.0043 0.03
Brugia malayi putative neuropeptide receptor NPR1 0.0007 0.0003 0.0019
Schistosoma mansoni ap endonuclease 0.0029 0.0176 0.0334
Echinococcus multilocularis FTZ F1 alpha 0.003 0.0183 0.0182
Schistosoma mansoni biogenic amine receptor 0.0007 0.0003 0.0001
Brugia malayi Calcitonin receptor-like protein seb-1 0.0115 0.0854 0.5901
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0007 0.0003 0.0001
Brugia malayi ORL1-like opioid receptor 0.0007 0.0003 0.0019
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0187 0.1422 1
Trypanosoma cruzi hypothetical protein, conserved 0.0012 0.0043 0.016
Loa Loa (eye worm) transcription factor SMAD2 0.0185 0.1406 0.9715
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0008 0.0008 0.0007
Echinococcus granulosus rhodopsin orphan GPCR 0.0007 0.0003 0.0004
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0042 0.0275 0.4744
Loa Loa (eye worm) G-protein coupled receptor 0.0007 0.0003 0.0015
Echinococcus multilocularis mothers against decapentaplegic 5 0.0013 0.0046 0.0045
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.0008 0.0013 0.0007
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0026 0.0152 0.029
Echinococcus multilocularis geminin 0.0667 0.5206 0.5206
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0028 0.0166 0.1144
Onchocerca volvulus 0.0036 0.0227 0.2066
Onchocerca volvulus 0.0011 0.0037 0.0319
Schistosoma mansoni DNA polymerase IV / kappa 0.0008 0.001 0.0015
Onchocerca volvulus 0.0007 0.0003 0.0005
Trichomonas vaginalis reverse transcriptase [C. elegans], putative 0.0012 0.0043 0.0249
Brugia malayi Animal haem peroxidase family protein 0.0036 0.0227 0.1567
Brugia malayi nuclear hormone receptor 0.0014 0.0058 0.04
Toxoplasma gondii LsmAD domain-containing protein 0.0021 0.0108 0.0972
Echinococcus granulosus protein jagged 1 0.0011 0.0037 0.007
Brugia malayi Pao retrotransposon peptidase family protein 0.0012 0.0043 0.03
Onchocerca volvulus Peroxidasin homolog 0.0036 0.0227 0.2066
Loa Loa (eye worm) beta-lactamase 0.0029 0.0177 0.122
Brugia malayi Pao retrotransposon peptidase family protein 0.0012 0.0043 0.03
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0007 0.0003 0.0001
Echinococcus multilocularis nuclear receptor nhr 48 0.0014 0.0058 0.0057
Echinococcus granulosus protein kinase c iota type 0.0008 0.0006 0.001
Loa Loa (eye worm) CXXC zinc finger family protein 0.0021 0.0113 0.0778
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0014 0.0058 0.0395
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.003 0.0183 0.1263
Echinococcus granulosus Smad4 0.0013 0.0046 0.0087
Brugia malayi jmjC domain containing protein 0.0048 0.0324 0.2235
Onchocerca volvulus 0.0007 0.0003 0.0005
Trichomonas vaginalis D-aminoacylase, putative 0.0029 0.0177 0.1179
Onchocerca volvulus 0.0021 0.0113 0.102
Loa Loa (eye worm) MH2 domain-containing protein 0.0013 0.0046 0.0311
Echinococcus multilocularis dna polymerase eta 0.0042 0.0275 0.0274
Trypanosoma brucei SLACS reverse transcriptase, putative 0.0012 0.0043 0.0079
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0067 0.0478 0.0477
Onchocerca volvulus Peroxidasin homolog 0.0036 0.0227 0.2066
Echinococcus multilocularis RNA directed DNA polymerase (reverse transcriptase) 0.0012 0.0043 0.0043
Treponema pallidum exodeoxyribonuclease (exoA) 0.0029 0.0176 0.0589
Trypanosoma brucei DNA polymerase kappa, putative 0.0026 0.0152 0.0335
Loa Loa (eye worm) hypothetical protein 0.0029 0.0177 0.122
Echinococcus multilocularis slit 2 protein 0.0011 0.0037 0.0036
Loa Loa (eye worm) hypothetical protein 0.0007 0.0003 0.0015
Schistosoma mansoni amine GPCR 0.0007 0.0003 0.0001
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0048 0.0324 0.062
Loa Loa (eye worm) hypothetical protein 0.0064 0.0453 0.3129
Loa Loa (eye worm) Smad1 0.0013 0.0046 0.0311
Echinococcus multilocularis sex peptide receptor 0.0007 0.0003 0.0002
Schistosoma mansoni myosin xvIII 0.0007 0.0003 0.0001
Loa Loa (eye worm) hypothetical protein 0.0007 0.0001 0.0004
Loa Loa (eye worm) hypothetical protein 0.0036 0.0227 0.1563
Echinococcus granulosus nuclear receptor 2DBD gamma 0.003 0.0183 0.035
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.0037 0.0235 0.0634
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0067 0.0478 0.0914
Leishmania major squalene monooxygenase-like protein 0.0273 0.2099 1
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0007 0.0003 0.0002
Brugia malayi Melibiase family protein 0.0056 0.0384 0.2656
Brugia malayi Pao retrotransposon peptidase family protein 0.0012 0.0043 0.03
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0036 0.0233 0.0447
Mycobacterium ulcerans DNA polymerase IV 0.0026 0.0152 0.3236
Loa Loa (eye worm) ATP-binding cassette sub-family B member 2 0.0008 0.0008 0.0047
Brugia malayi isocitrate dehydrogenase 0.0012 0.0038 0.0263
Schistosoma mansoni nuclear hormone receptor 0.0014 0.0058 0.0107
Schistosoma mansoni hypothetical protein 0.0011 0.0037 0.0067
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0008 0.0008 0.0007
Leishmania major DNA polymerase kappa, putative 0.0008 0.001 0.0012
Trypanosoma cruzi squalene monooxygenase, putative 0.0273 0.2099 1
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0026 0.0152 0.1002
Schistosoma mansoni nuclear hormone receptor 0.003 0.0183 0.0347
Loa Loa (eye worm) hypothetical protein 0.0009 0.0017 0.0116
Trypanosoma brucei retrotransposon hot spot protein 4 (RHS4), interrupted 0.0157 0.1187 0.2786
Echinococcus granulosus g protein coupled receptor 0.0007 0.0003 0.0004
Loa Loa (eye worm) hypothetical protein 0.0042 0.0275 0.1896
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0037 0.0237 0.159
Entamoeba histolytica hypothetical protein 0.0056 0.0386 0.1045
Echinococcus multilocularis serotonin receptor 0.0007 0.0003 0.0002
Echinococcus multilocularis serotonin receptor 0.0007 0.0003 0.0002
Onchocerca volvulus 0.003 0.0183 0.1661
Entamoeba histolytica serine/threonine protein kinase, putative 0.0077 0.0554 0.1502
Giardia lamblia Reverse transcriptase/endonuclease, putative 0.0012 0.0043 0.0309
Echinococcus granulosus rhodopsin orphan GPCR 0.0007 0.0003 0.0004
Trichomonas vaginalis C-MYB, putative 0.0037 0.0235 0.1581
Trypanosoma cruzi ribonuclease H1, putative 0.0145 0.109 0.5168
Trichomonas vaginalis glucosylceramidase, putative 0.0132 0.0984 0.6783
Brugia malayi tailless protein 0.0014 0.0058 0.04
Schistosoma mansoni notch 0.0011 0.0037 0.0067
Loa Loa (eye worm) hypothetical protein 0.0007 0.0003 0.0015
Onchocerca volvulus 0.0007 0.0003 0.0005
Loa Loa (eye worm) animal heme peroxidase 0.0036 0.0227 0.1563
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.003 0.0183 0.1259
Echinococcus granulosus fibropellin Ia 0.0011 0.0037 0.007
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0012 0.0038 0.0694
Loa Loa (eye worm) hypothetical protein 0.0014 0.0058 0.0395
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0007 0.0003 0.0015
Brugia malayi hypothetical protein 0.0012 0.0043 0.03
Echinococcus granulosus mothers against decapentaplegic 5 0.0013 0.0046 0.0087
Loa Loa (eye worm) jmjC domain-containing protein 0.0013 0.0047 0.0319
Trypanosoma cruzi DNA polymerase eta, putative 0.0024 0.0133 0.059
Loa Loa (eye worm) jmjC domain-containing protein 0.0049 0.0333 0.2298
Echinococcus granulosus g protein coupled receptor 0.0007 0.0003 0.0004
Schistosoma mansoni hypothetical protein 0.0036 0.0233 0.0444
Toxoplasma gondii exonuclease III APE 0.0029 0.0176 0.16
Schistosoma mansoni RAR-like nuclear receptor 0.003 0.0183 0.0347
Onchocerca volvulus 0.0029 0.0177 0.1609
Onchocerca volvulus 0.0011 0.0037 0.0319
Brugia malayi reverse transcriptase 0.0012 0.0043 0.03
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0026 0.0152 0.1044
Plasmodium falciparum ataxin-2 like protein, putative 0.0021 0.0108 0.228
Mycobacterium tuberculosis Probable lipase LipD 0.0029 0.0177 0.12
Onchocerca volvulus 0.0077 0.0551 0.5045
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0067 0.0478 0.0477
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0014 0.0058 0.0107
Onchocerca volvulus 0.0007 0.0003 0.0005
Brugia malayi reverse transcriptase 0.0012 0.0043 0.03
Schistosoma mansoni smad1 5 8 and 0.0013 0.0046 0.0084
Loa Loa (eye worm) hypothetical protein 0.0007 0.0003 0.0015
Echinococcus granulosus neuropeptide Y receptor 0.0007 0.0003 0.0004
Schistosoma mansoni growth hormone secretagogue receptor 0.0007 0.0003 0.0001
Echinococcus multilocularis Diacylglycerol kinase theta 0.0007 0.0002 0.0002
Onchocerca volvulus 0.0007 0.0003 0.0005
Echinococcus granulosus multidrug resistance protein 1 0.0008 0.0008 0.0013
Echinococcus multilocularis raf serine:threonine protein kinase 0.0007 0.0002 0.0002
Brugia malayi multidrug resistance protein 3 0.0008 0.0008 0.0052
Onchocerca volvulus 0.0036 0.0227 0.2066
Loa Loa (eye worm) hypothetical protein 0.0007 0.0003 0.0015
Brugia malayi Melatonin receptor type 1A 0.0007 0.0003 0.0019
Brugia malayi ABC transporter family protein 0.0008 0.0008 0.0052
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0064 0.0448 0.3388
Brugia malayi nuclear hormone receptor family member odr-7 0.0014 0.0058 0.04
Brugia malayi Zinc knuckle family protein 0.0012 0.0043 0.03
Echinococcus multilocularis RNA directed DNA polymerase (reverse transcriptase) 0.0012 0.0043 0.0043
Echinococcus multilocularis telomerase reverse transcriptase subunit 0.0012 0.0043 0.0043
Schistosoma mansoni transcription factor LCR-F1 0.0056 0.0386 0.0738
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.001 0.0026 0.0045
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0026 0.0152 0.102
Brugia malayi nuclear receptor NHR-67 0.0014 0.0058 0.04
Onchocerca volvulus 0.0007 0.0003 0.0005
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0007 0.0003 0.0004
Mycobacterium leprae conserved hypothetical protein 0.0029 0.0177 0.1768
Loa Loa (eye worm) hypothetical protein 0.0133 0.0996 0.6877
Echinococcus multilocularis peptidase Clp (S14 family) 0.0042 0.0275 0.0274
Echinococcus multilocularis neuropeptide receptor A26 0.0346 0.2677 0.2676
Trypanosoma brucei hypothetical protein, conserved 0.0157 0.1187 0.2786
Brugia malayi RNase H family protein 0.0145 0.109 0.7529
Echinococcus multilocularis neurogenic locus notch protein 0.0011 0.0037 0.0036
Loa Loa (eye worm) hypothetical protein 0.0122 0.0905 0.6248
Echinococcus multilocularis protein jagged 1 0.0011 0.0037 0.0036
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.0037 0.0235 0.0634
Loa Loa (eye worm) hypothetical protein 0.0056 0.0384 0.2653
Brugia malayi hypothetical protein 0.0007 0.0003 0.0019
Schistosoma mansoni peroxidasin 0.0036 0.0227 0.0432
Entamoeba histolytica P-glyco protein 6, putative 0.0008 0.0008 0.0014
Echinococcus granulosus Diacylglycerol kinase theta 0.0007 0.0002 0.0003
Brugia malayi neuropeptide F receptor 0.0007 0.0003 0.0019
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0064 0.0448 1
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0042 0.0275 0.1892
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0007 0.0003 0.0005
Trypanosoma cruzi squalene monooxygenase, putative 0.0273 0.2099 1
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0014 0.0058 0.0057
Echinococcus granulosus JmjC domain containing protein 4 0.0013 0.0047 0.0089
Loa Loa (eye worm) hypothetical protein 0.0011 0.0037 0.025
Loa Loa (eye worm) hypothetical protein 0.0008 0.0008 0.0047
Echinococcus multilocularis isocitrate dehydrogenase 0.0012 0.0038 0.0037
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0007 0.0003 0.0001
Brugia malayi Serotonin receptor 0.0007 0.0003 0.0019
Loa Loa (eye worm) RasGEF domain-containing protein 0.0009 0.0015 0.0096
Brugia malayi GCC2 and GCC3 family protein 0.0011 0.0037 0.0255
Schistosoma mansoni phd/f-box containing protein 0.0013 0.0047 0.0086
Entamoeba histolytica P-glycoprotein-2, putative 0.0008 0.0008 0.0014
Loa Loa (eye worm) hypothetical protein 0.0007 0.0003 0.0015
Entamoeba histolytica P-glycoprotein-2 0.0008 0.0008 0.0014
Brugia malayi Pao retrotransposon peptidase family protein 0.0012 0.0043 0.03
Onchocerca volvulus 0.0011 0.0037 0.0319
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0008 0.0013 0.0015
Brugia malayi protein kinase C3,putative 0.0008 0.0006 0.0041
Loa Loa (eye worm) hypothetical protein 0.0016 0.0071 0.0488
Echinococcus multilocularis multidrug resistance protein 1 0.0008 0.0008 0.0007
Echinococcus multilocularis neurogenic locus protein delta 0.0011 0.0037 0.0036
Brugia malayi Nuclear hormone receptor family member nhr-1 0.003 0.0183 0.1263
Brugia malayi nuclear hormone receptor 0.003 0.0183 0.1263
Echinococcus granulosus retinoic acid receptor rxr beta a 0.003 0.0183 0.035
Schistosoma mansoni hypothetical protein 0.0011 0.0037 0.0067
Loa Loa (eye worm) hypothetical protein 0.0013 0.0047 0.0319
Brugia malayi ecdysteroid receptor 0.003 0.0183 0.1263
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0008 0.001 0.0072
Echinococcus multilocularis C2 calcium dependent membrane targeting 0.0007 0.0002 0.0002
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.003 0.0183 0.0182
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.001 0.0026 0.0025
Loa Loa (eye worm) hypothetical protein 0.0014 0.0058 0.0395
Loa Loa (eye worm) hypothetical protein 0.0036 0.0227 0.1563
Loa Loa (eye worm) hypothetical protein 0.0036 0.0227 0.1563
Loa Loa (eye worm) hypothetical protein 0.0007 0.0003 0.0015
Brugia malayi RhoGAP domain containing protein 0.0007 0.0002 0.0015
Schistosoma mansoni steroid hormone receptor ad4bp 0.003 0.0183 0.0347
Brugia malayi reverse transcriptase 0.0012 0.0043 0.03
Schistosoma mansoni notch 0.0011 0.0037 0.0067
Loa Loa (eye worm) hypothetical protein 0.0011 0.0037 0.025
Trichomonas vaginalis glucosylceramidase, putative 0.019 0.1447 1
Onchocerca volvulus 0.0014 0.0058 0.0512
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0022 0.0119 0.2533
Echinococcus granulosus N chimaerin 0.0007 0.0002 0.0003
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0115 0.0854 0.5899
Onchocerca volvulus 0.0012 0.0043 0.0378
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0007 0.0003 0.0004
Schistosoma mansoni neuropeptide receptor 0.0007 0.0003 0.0001
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0013 0.0047 0.041
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0007 0.0003 0.0004
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0016 0.0071 0.0488
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0007 0.0003 0.0002
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0029 0.0177 0.3818
Brugia malayi Cadherin domain containing protein 0.0011 0.0037 0.0255
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.019 0.1447 1
Echinococcus granulosus peptide allatostatin:somatostatin 0.0007 0.0003 0.0004
Echinococcus granulosus smad 0.0013 0.0046 0.0087
Loa Loa (eye worm) hypothetical protein 0.0011 0.0037 0.025
Leishmania major DNA damage repair protein, putative 0.0008 0.001 0.0012
Brugia malayi Probable ClpP-like protease 0.0064 0.0448 0.3095
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0103 0.0194
Schistosoma mansoni thyroid hormone receptor 0.003 0.0183 0.0347
Trichomonas vaginalis glucosylceramidase, putative 0.0125 0.0931 0.6415
Brugia malayi Delta serrate ligand family protein 0.0011 0.0037 0.0255
Echinococcus granulosus neuropeptide s receptor 0.0346 0.2677 0.5141
Echinococcus multilocularis g protein coupled receptor 0.0007 0.0003 0.0002
Echinococcus multilocularis RNA directed DNA polymerase (reverse transcriptase) 0.0012 0.0043 0.0043
Brugia malayi MH2 domain containing protein 0.0013 0.0046 0.0316
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0014 0.0058 0.011
Loa Loa (eye worm) hypothetical protein 0.0013 0.0047 0.0319
Brugia malayi hypothetical protein 0.0007 0.0003 0.0019
Echinococcus granulosus G protein coupled receptor 139 0.0007 0.0003 0.0004
Schistosoma mansoni hypothetical protein 0.0011 0.0037 0.0067
Brugia malayi EGF-like domain containing protein 0.0011 0.0037 0.0255
Echinococcus granulosus biogenic amine 5HT receptor 0.0007 0.0003 0.0004
Brugia malayi Pao retrotransposon peptidase family protein 0.0012 0.0043 0.03
Loa Loa (eye worm) animal heme peroxidase 0.0036 0.0227 0.1563
Brugia malayi hypothetical protein 0.0056 0.0386 0.2668
Mycobacterium tuberculosis Possible maturase 0.0012 0.0043 0.0253
Echinococcus multilocularis ATP binding cassette sub family B 0.0008 0.0007 0.0006
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0014 0.0056 0.0056
Trichomonas vaginalis glucosylceramidase, putative 0.019 0.1447 1
Trypanosoma brucei unspecified product 0.0018 0.0088 0.0185
Trypanosoma cruzi DNA polymerase kappa, putative 0.0026 0.0152 0.0678
Loa Loa (eye worm) hypothetical protein 0.0007 0.0002 0.0011
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0029 0.0176 0.383
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0036 0.0233 0.1613
Trichomonas vaginalis CAMK family protein kinase 0.0077 0.0554 0.3795
Echinococcus multilocularis smad 0.0013 0.0046 0.0045
Brugia malayi diacylglycerol kinase 0.0007 0.0002 0.0015
Echinococcus granulosus tm gpcr rhodopsin 0.0007 0.0003 0.0004
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0007 0.0003 0.0001
Loa Loa (eye worm) jmjC domain-containing protein 0.0013 0.0047 0.0319
Echinococcus granulosus unc 13 munc13 0.0007 0.0002 0.0003
Giardia lamblia Kinase, PLK 0.0077 0.0554 0.5038
Echinococcus multilocularis thyroid hormone receptor alpha 0.003 0.0183 0.0182
Trichomonas vaginalis pc-MYB2, putative 0.0037 0.0235 0.1581
Loa Loa (eye worm) hypothetical protein 0.0007 0.0003 0.0015
Echinococcus granulosus dro:myosuppressin receptor 0.0007 0.0003 0.0004
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0014 0.0058 0.0107
Echinococcus granulosus jumonji domain containing 1A 0.0013 0.0047 0.0089
Loa Loa (eye worm) hypothetical protein 0.0007 0.0003 0.0015
Onchocerca volvulus Peroxidase homolog 0.0036 0.0227 0.2066
Echinococcus granulosus C2 calcium dependent membrane targeting 0.0007 0.0002 0.0003
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0008 0.0006 0.001
Loa Loa (eye worm) hypothetical protein 0.0011 0.0037 0.025
Loa Loa (eye worm) hypothetical protein 0.0011 0.0037 0.025
Echinococcus granulosus Rac GTPase activating protein 1 0.0007 0.0002 0.0003
Schistosoma mansoni septate junction protein 0.0011 0.0037 0.0067
Schistosoma mansoni hypothetical protein 0.0667 0.5206 1
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0166 0.1102
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.0037 0.0235 0.0634
Trichomonas vaginalis NeSL-1_NeSL reverse transcriptases, putative 0.0012 0.0043 0.0249
Mycobacterium tuberculosis Conserved protein 0.0029 0.0177 0.12
Loa Loa (eye worm) hypothetical protein 0.0036 0.0227 0.1563
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0008 0.0006 0.0005
Loa Loa (eye worm) hypothetical protein 0.0007 0.0003 0.0015
Schistosoma mansoni protein kinase C mu 0.0065 0.0457 0.0874
Loa Loa (eye worm) hypothetical protein 0.0014 0.0058 0.0395
Onchocerca volvulus 0.0066 0.0469 0.4288
Echinococcus granulosus neuropeptides capa receptor 0.0007 0.0003 0.0004
Echinococcus multilocularis neuropeptides capa receptor 0.0007 0.0003 0.0002
Echinococcus multilocularis Smad4 0.0013 0.0046 0.0045
Loa Loa (eye worm) hypothetical protein 0.0007 0.0003 0.0015
Loa Loa (eye worm) hypothetical protein 0.0007 0.0003 0.0015
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0029 0.0176 0.0474
Loa Loa (eye worm) hypothetical protein 0.0021 0.0108 0.0741
Loa Loa (eye worm) hypothetical protein 0.0011 0.0037 0.025
Schistosoma mansoni hypothetical protein 0.0009 0.0019 0.0032
Echinococcus granulosus ecdysone induced protein 78C 0.003 0.0183 0.035
Loa Loa (eye worm) multidrug resistance protein 3 0.0008 0.0008 0.0047
Loa Loa (eye worm) hypothetical protein 0.0007 0.0003 0.0015
Loa Loa (eye worm) hypothetical protein 0.003 0.0183 0.1259
Onchocerca volvulus 0.0008 0.0008 0.0049
Leishmania major peptidyl-prolyl cis-trans isomerase, putative 0.0008 0.0013 0.0027
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0007 0.0002 0.0003
Loa Loa (eye worm) hypothetical protein 0.0014 0.0058 0.0395
Loa Loa (eye worm) G-protein coupled receptor 0.0007 0.0003 0.0015
Entamoeba histolytica P-glycoprotein 5, putative 0.0008 0.0008 0.0014
Trichomonas vaginalis glucosylceramidase, putative 0.0132 0.0984 0.6783
Schistosoma mansoni neuropeptide F-like receptor 0.0007 0.0003 0.0001
Echinococcus granulosus peroxidasin 0.0036 0.0227 0.0435
Echinococcus multilocularis neuropeptide receptor 0.0007 0.0003 0.0002
Trypanosoma brucei DNA polymerase kappa, putative 0.0026 0.0152 0.0335
Brugia malayi Nuclear hormone receptor family member nhr-40 0.003 0.0183 0.1263
Trypanosoma brucei DNA polymerase kappa, putative 0.0026 0.0152 0.0335
Loa Loa (eye worm) hypothetical protein 0.0011 0.0037 0.025
Trichomonas vaginalis ribonuclease H1, putative 0.0145 0.109 0.7516
Onchocerca volvulus 0.0011 0.0037 0.0319
Brugia malayi Pao retrotransposon peptidase family protein 0.0012 0.0043 0.03
Echinococcus granulosus neuropeptide FF receptor 2 0.0007 0.0003 0.0004
Trypanosoma brucei polo-like protein kinase 0.0077 0.0554 0.1288
Plasmodium vivax ataxin-2 like protein, putative 0.0021 0.0108 0.228
Brugia malayi EGF-like domain containing protein 0.0011 0.0037 0.0255
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.001 0.0026 0.0045
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.003 0.0183 0.0347
Trichomonas vaginalis glucosylceramidase, putative 0.019 0.1447 1
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.0037 0.0235 0.0634
Echinococcus multilocularis beta LACTamase domain containing family member 0.0029 0.0177 0.0177
Echinococcus granulosus notch 0.0011 0.0037 0.007
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0036 0.0233 0.0233
Trypanosoma brucei unspecified product 0.0157 0.1187 0.2786
Echinococcus granulosus rhodopsin orphan GPCR 0.0007 0.0003 0.0004
Schistosoma mansoni multidrug resistance protein 0.0008 0.0008 0.001
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0029 0.0177 0.1224
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0064 0.0448 1
Echinococcus granulosus neuropeptide receptor 0.0007 0.0003 0.0004
Loa Loa (eye worm) notch protein 0.0011 0.0037 0.025

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 41 nM Binding affinity for human cloned vasopressin V1a receptor expressed in CHO cells ChEMBL. 17234419
IC50 (binding) = 41 nM Binding affinity for human cloned vasopressin V1a receptor expressed in CHO cells ChEMBL. 17234419

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

No external resources registered for this compound

Bibliographic References

1 literature reference was collected for this gene.

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