Detailed information for compound 452910

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 538.686 | Formula: C31H56BrNO
  • H donors: 0 H acceptors: 1 LogP: 11.83 Rotable bonds: 22
    Rule of 5 violations (Lipinski): 2
  • SMILES: CCCCCCCCN(C(=O)/C=C/C(C/C=C(/CC/C=C(/Br)\C)\C)(C)C)CCCCCCCC
  • InChi: 1S/C31H56BrNO/c1-7-9-11-13-15-17-26-33(27-18-16-14-12-10-8-2)30(34)23-25-31(5,6)24-22-28(3)20-19-21-29(4)32/h21-23,25H,7-20,24,26-27H2,1-6H3/b25-23+,28-22+,29-21+
  • InChiKey: PMOSKGLLDFIAMN-OJQICJQXSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis serotonin receptor 0.0034 0.0069 0.0139
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0006 0.0003 0.0015
Echinococcus granulosus multidrug resistance protein 1 0.0011 0.0015 0.003
Trypanosoma brucei DNA topoisomerase IB, large subunit 0.0078 0.0169 1
Trypanosoma brucei DNA polymerase IV, putative 0.0006 0.0003 0.0156
Echinococcus granulosus replication protein A 70 kDa DNA binding 0.001 0.0014 0.0027
Brugia malayi jmjC domain containing protein 0.0019 0.0035 0.0234
Loa Loa (eye worm) histone methyltransferase 0.0013 0.002 0.0132
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0007 0.0006 0.0012
Loa Loa (eye worm) hypothetical protein 0.0034 0.0069 0.0465
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0034 0.0069 0.0139
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0006 0.0003 0.009
Entamoeba histolytica hypothetical protein 0.0112 0.0247 1
Brugia malayi acetyltransferase, GNAT family protein 0.0164 0.0364 0.2448
Brugia malayi Isocitrate dehydrogenase 0.0015 0.0025 0.0166
Echinococcus multilocularis agrin 0.0009 0.001 0.0021
Echinococcus multilocularis expressed protein 0.0097 0.0212 0.0427
Schistosoma mansoni amine GPCR 0.0034 0.0069 0.0139
Loa Loa (eye worm) steroid hormone receptor 0.0007 0.0006 0.0039
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.002 0.0036 0.0034
Echinococcus multilocularis neuropeptide Y receptor 0.0034 0.0069 0.0139
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0006 0.0003 0.0007
Leishmania major DNA topoisomerase IB, large subunit 0.0078 0.0169 1
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0034 0.0069 0.0139
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.004 0.0082 0.3292
Echinococcus granulosus axis inhibition protein axin 0.0005 0.0002 0.0004
Loa Loa (eye worm) hypothetical protein 0.0043 0.0089 0.0596
Mycobacterium tuberculosis Probable reductase 0.0083 0.0179 0.0177
Trichomonas vaginalis alpha-glucosidase, putative 0.004 0.0082 0.0478
Echinococcus granulosus regulator of G protein signaling 7 0.0005 0.0002 0.0004
Trichomonas vaginalis alpha-glucosidase, putative 0.0015 0.0024 0.0141
Echinococcus multilocularis FTZ F1 alpha 0.0007 0.0006 0.0012
Echinococcus granulosus tm gpcr rhodopsin 0.0034 0.0069 0.0139
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0007 0.0006 0.0012
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0015 0.0025 0.005
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0091 0.0197 0.0397
Trypanosoma cruzi major cysteine proteinase, putative 0.0011 0.0017 0.0945
Echinococcus multilocularis multidrug resistance protein 1 0.0007 0.0008 0.0015
Echinococcus granulosus zinc finger protein 0.0006 0.0004 0.0007
Brugia malayi Patched family protein 0.0006 0.0004 0.003
Schistosoma mansoni tsg101-related 0.005 0.0104 0.0209
Schistosoma mansoni hypothetical protein 0.007 0.0151 0.0305
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0021 0.0039 0.2289
Echinococcus granulosus histone acetyltransferase KAT2B 0.0159 0.0354 0.0712
Echinococcus granulosus 7tm_1 domain containing protein 0.0034 0.0069 0.0139
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0034 0.0069 0.0139
Loa Loa (eye worm) TYRA-2 protein 0.0034 0.0069 0.0465
Schistosoma mansoni organic anion transporter 0.0013 0.0019 0.0039
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0019 0.0035 0.203
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0034 0.0069 0.0139
Giardia lamblia Thioredoxin reductase 0.0006 0.0003 0.0016
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0007 0.0006 0.0012
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0011 0.0015 0.003
Mycobacterium ulcerans NADH dehydrogenase Ndh 0.0006 0.0003 0.0001
Echinococcus granulosus mothers against decapentaplegic 5 0.0009 0.001 0.0021
Brugia malayi SET domain containing protein 0.0006 0.0004 0.0026
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0007 0.0006 0.0012
Echinococcus granulosus dro:myosuppressin receptor 0.0034 0.0069 0.0139
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0006 0.0003 0.0001
Loa Loa (eye worm) ATP-binding cassette sub-family B member 2 0.0011 0.0015 0.0099
Schistosoma mansoni SET domain protein 0.0006 0.0004 0.0008
Echinococcus multilocularis regulator of G protein signaling 0.0005 0.0002 0.0004
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0014 0.0024 0.1365
Schistosoma mansoni hypothetical protein 0.0033 0.0065 0.0131
Echinococcus multilocularis g protein coupled receptor 0.0034 0.0069 0.0139
Schistosoma mansoni hypothetical protein 0.006 0.0128 0.0257
Loa Loa (eye worm) hypothetical protein 0.0034 0.0069 0.0465
Echinococcus multilocularis Niemann Pick C1 protein 0.01 0.022 0.0442
Plasmodium falciparum glutathione reductase 0.0062 0.0131 0.7722
Trypanosoma cruzi hypothetical protein, conserved 0.0006 0.0003 0.0167
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0009 0.001 0.0423
Schistosoma mansoni follistatin 0.0009 0.001 0.0021
Brugia malayi hypothetical protein 0.0013 0.0019 0.0131
Mycobacterium ulcerans aldehyde dehydrogenase 0.0064 0.0137 0.0134
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0034 0.0069 0.0139
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0034 0.0069 0.0139
Brugia malayi Niemann-Pick C1 protein precursor 0.01 0.022 0.1475
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0015 0.0025 0.005
Trypanosoma brucei glucosidase, putative 0.004 0.0082 0.4807
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0043 0.0089 0.0596
Brugia malayi hypothetical protein 0.0053 0.0113 0.0756
Schistosoma mansoni neuropeptide f receptor 76f 0.0034 0.0069 0.0139
Trichomonas vaginalis conserved hypothetical protein 0.0005 0.0002 0.0008
Schistosoma mansoni DNA topoisomerase type I 0.0078 0.0169 0.034
Loa Loa (eye worm) hypothetical protein 0.0034 0.0069 0.0465
Loa Loa (eye worm) transcription factor SMAD2 0.0127 0.028 0.1879
Echinococcus granulosus sterol regulatory element binding protein 0.0043 0.0089 0.0179
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0011 0.0016 0.0014
Schistosoma mansoni RAR-like nuclear receptor 0.0007 0.0006 0.0012
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0034 0.0069 0.0465
Trichomonas vaginalis alpha-glucosidase, putative 0.0015 0.0024 0.0141
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0005 0.0002 0.0012
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0021 0.0039 0.1833
Echinococcus granulosus regulator of G protein signaling 3 0.0005 0.0002 0.0004
Brugia malayi ABC transporter family protein 0.0008 0.001 0.0066
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0005 0.0002 0.0004
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0011 0.0016 0.0942
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0064 0.0137 0.0275
Onchocerca volvulus 0.0034 0.0069 0.0395
Brugia malayi hypothetical protein 0.0006 0.0004 0.003
Entamoeba histolytica thioredoxin reductase, putative 0.0006 0.0003 0.0121
Schistosoma mansoni organic anion transporter 0.0013 0.0019 0.0039
Schistosoma mansoni tar DNA-binding protein 0.0133 0.0294 0.0592
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0064 0.0137 0.8079
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0015 0.0025 0.0022
Trichomonas vaginalis replication factor A 1, rfa1, putative 0.001 0.0012 0.007
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0021 0.0039 0.2289
Echinococcus multilocularis g protein coupled receptor 0.0034 0.0069 0.0139
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0007 0.0006 0.0039
Echinococcus multilocularis rhodopsin orphan GPCR 0.0034 0.0069 0.0139
Brugia malayi G protein-coupled receptor 0.0034 0.0069 0.0466
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0014 0.0022 0.015
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0098 0.0215 0.0212
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0011 0.0016 0.3649
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0016 0.0026 0.0177
Loa Loa (eye worm) hypothetical protein 0.0021 0.0039 0.0264
Echinococcus multilocularis thioredoxin glutathione reductase 0.0062 0.0131 0.0264
Brugia malayi RNA binding protein 0.0133 0.0294 0.1975
Loa Loa (eye worm) hypothetical protein 0.0006 0.0004 0.0029
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0007 0.0006 0.0039
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0015 0.0025 0.005
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0034 0.0069 0.0139
Brugia malayi SPARC precursor 0.0009 0.001 0.0069
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0006 0.0003 0.0017
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0017 0.003 0.0199
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0021 0.0039 0.0037
Loa Loa (eye worm) hypothetical protein 0.0033 0.0065 0.0436
Onchocerca volvulus Bile acid receptor homolog 0.0007 0.0006 0.002
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0034 0.0069 0.0139
Echinococcus granulosus microtubule associated protein 2 0.218 0.4969 1
Trypanosoma cruzi ATP-binding cassette protein, putative 0.001 0.0013 0.0751
Echinococcus multilocularis carbonic anhydrase II 0.0015 0.0025 0.005
Schistosoma mansoni hypothetical protein 0.0033 0.0065 0.0131
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0012 0.0018 0.1054
Echinococcus multilocularis GPCR, family 2 0.0033 0.0065 0.0131
Plasmodium falciparum histone acetyltransferase GCN5 0.0044 0.0091 0.5354
Onchocerca volvulus 0.0011 0.0015 0.0073
Loa Loa (eye worm) phosphofructokinase 0.0011 0.0016 0.011
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0034 0.0069 0.0139
Brugia malayi hypothetical protein 0.0034 0.0069 0.0466
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0007 0.0007 0.0048
Onchocerca volvulus 0.0014 0.0023 0.0122
Schistosoma mansoni nuclear hormone receptor 0.0007 0.0006 0.0012
Trypanosoma cruzi DNA polymerase kappa, putative 0.0006 0.0003 0.0156
Trichomonas vaginalis apoptosis inducing factor, putative 0.0006 0.0003 0.0017
Brugia malayi secreted modular calcium-binding protein 1 0.0009 0.001 0.0069
Echinococcus granulosus hypothetical protein 0.0034 0.0069 0.0139
Loa Loa (eye worm) hypothetical protein 0.0034 0.0069 0.0465
Loa Loa (eye worm) hypothetical protein 0.0034 0.0069 0.0465
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0014 0.0024 0.1365
Schistosoma mansoni thyroid hormone receptor 0.0007 0.0006 0.0012
Schistosoma mansoni DNA polymerase eta 0.0006 0.0003 0.0007
Leishmania major protein kinase, putative 0.0007 0.0008 0.041
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0034 0.0069 0.0139
Loa Loa (eye worm) hypothetical protein 0.0034 0.0069 0.0465
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0007 0.0008 0.041
Loa Loa (eye worm) RNA binding protein 0.0133 0.0294 0.1975
Plasmodium falciparum ferrodoxin reductase-like protein 0.0006 0.0003 0.011
Loa Loa (eye worm) hypothetical protein 0.0034 0.0069 0.0465
Onchocerca volvulus Protein ultraspiracle homolog 0.0007 0.0006 0.002
Trichomonas vaginalis set domain proteins, putative 0.0747 0.1695 1
Schistosoma mansoni carbonic anhydrase-related 0.0015 0.0025 0.005
Loa Loa (eye worm) hypothetical protein 0.0006 0.0004 0.0029
Echinococcus granulosus nuclear factor of activated T cells 5 0.0021 0.0039 0.0079
Brugia malayi Glycosyl hydrolases family 31 protein 0.018 0.0401 0.2695
Mycobacterium tuberculosis Isocitrate lyase Icl (isocitrase) (isocitratase) 0.4383 1 1
Echinococcus multilocularis PHD finger protein rhinoceros 0.006 0.0128 0.0257
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0013 0.002 0.004
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.001 0.0013 0.0011
Schistosoma mansoni tar DNA-binding protein 0.0133 0.0294 0.0592
Schistosoma mansoni jumonji domain containing protein 0.0156 0.0348 0.07
Brugia malayi hypothetical protein 0.0035 0.0069 0.0466
Trypanosoma brucei unspecified product 0.0006 0.0003 0.0156
Schistosoma mansoni agrin 0.0009 0.001 0.0021
Brugia malayi hypothetical protein 0.0034 0.0069 0.0466
Schistosoma mansoni z-protein (S1r protein) 0.0005 0.0002 0.0004
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0007 0.0006 0.0012
Onchocerca volvulus 0.0006 0.0004 0.0011
Mycobacterium tuberculosis Probable epoxide hydrolase EphA (epoxide hydratase) (arene-oxide hydratase) 0.0046 0.0095 0.0093
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0014 0.0024 0.1365
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0034 0.0069 0.0139
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0034 0.0069 0.0139
Echinococcus multilocularis protein dispatched 1 0.0049 0.0103 0.0207
Echinococcus granulosus rhodopsin orphan GPCR 0.0034 0.0069 0.0139
Giardia lamblia NADH oxidase lateral transfer candidate 0.0021 0.0039 0.2887
Onchocerca volvulus 0.0034 0.0069 0.0395
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0011 0.0015 0.0084
Loa Loa (eye worm) hypothetical protein 0.0034 0.0069 0.0465
Loa Loa (eye worm) hypothetical protein 0.0007 0.0006 0.0039
Trypanosoma brucei DNA polymerase kappa, putative 0.0006 0.0003 0.0156
Loa Loa (eye worm) hypothetical protein 0.0014 0.0023 0.0155
Loa Loa (eye worm) hypothetical protein 0.0034 0.0069 0.0465
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0006 0.0003 0.0016
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0007 0.0007 0.0015
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0006 0.0003 0.009
Schistosoma mansoni biogenic amine receptor 0.0034 0.0069 0.0139
Schistosoma mansoni regulator of G protein signaling 0.0005 0.0002 0.0004
Echinococcus granulosus tm gpcr rhodopsin 0.0034 0.0069 0.0139
Mycobacterium tuberculosis NADPH:adrenodoxin oxidoreductase FprA (NADPH-ferredoxin reductase) 0.0006 0.0003 0.0001
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0036 0.1679
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0006 0.0003 0.0007
Brugia malayi Regulator of G protein signaling domain containing protein 0.0005 0.0002 0.0013
Echinococcus granulosus carbonic anhydrase 0.0015 0.0025 0.005
Loa Loa (eye worm) hypothetical protein 0.0073 0.0157 0.1055
Leishmania major trypanothione reductase 0.0062 0.0131 0.7735
Toxoplasma gondii DNA topoisomerase I, putative 0.0078 0.0169 0.817
Loa Loa (eye worm) hypothetical protein 0.0013 0.0019 0.013
Loa Loa (eye worm) hypothetical protein 0.0034 0.0069 0.0465
Onchocerca volvulus 0.0034 0.0069 0.0395
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0021 0.0039 0.2244
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0011 0.0016 0.0031
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0007 0.0006 0.0012
Toxoplasma gondii patched family protein 0.0006 0.0004 0.0137
Brugia malayi jmjC domain containing protein 0.0019 0.0035 0.0234
Loa Loa (eye worm) hypothetical protein 0.0007 0.0006 0.0039
Toxoplasma gondii PHD-finger domain-containing protein 0.002 0.0035 0.1647
Brugia malayi hypothetical protein 0.0073 0.0157 0.1055
Trichomonas vaginalis conserved hypothetical protein 0.0005 0.0002 0.0008
Loa Loa (eye worm) hypothetical protein 0.0006 0.0004 0.0029
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0007 0.0006 0.0039
Trichomonas vaginalis guanylate cyclase, putative 0.0007 0.0007 0.0039
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0005 0.0002 0.0004
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0011 0.0015 0.0084
Loa Loa (eye worm) multidrug resistance protein 3 0.0011 0.0015 0.0099
Schistosoma mansoni single-minded 0.0028 0.0055 0.011
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0007 0.0006 0.0012
Brugia malayi Patched family protein 0.0006 0.0004 0.003
Echinococcus multilocularis dna polymerase eta 0.0006 0.0003 0.0007
Giardia lamblia Glutamate synthase 0.0006 0.0003 0.0016
Schistosoma mansoni amine GPCR 0.0034 0.0069 0.0139
Echinococcus granulosus neuropeptide s receptor 0.0034 0.0069 0.0139
Echinococcus granulosus histone acetyltransferase KAT2B 0.0048 0.01 0.0202
Trichomonas vaginalis ABC transporter, putative 0.0011 0.0015 0.0084
Trypanosoma brucei DNA polymerase kappa, putative 0.0006 0.0003 0.0156
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0021 0.0039 0.2289
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0826 0.1877 0.3778
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0021 0.0039 0.1833
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0034 0.0069 0.0139
Brugia malayi sodium-independent organic anion transporter family protein 0.0013 0.0019 0.0131
Schistosoma mansoni terminal deoxycytidyl transferase 0.0006 0.0003 0.0007
Loa Loa (eye worm) hypothetical protein 0.0006 0.0004 0.0029
Loa Loa (eye worm) hypothetical protein 0.0006 0.0004 0.0029
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0012 0.0018 0.1054
Schistosoma mansoni hypothetical protein 0.0033 0.0065 0.0131
Brugia malayi Patched family protein 0.0006 0.0004 0.003
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0034 0.0069 0.0465
Brugia malayi prostaglandin transporter 0.0013 0.0019 0.0131
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0007 0.0006 0.0012
Echinococcus multilocularis DNA topoisomerase 1 0.0078 0.0169 0.034
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0011 0.0015 0.003
Entamoeba histolytica phosphofructokinase, putative 0.0011 0.0016 0.065
Brugia malayi Patched family protein 0.0006 0.0004 0.003
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.002 0.0036 0.0242
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0006 0.0003 0.009
Echinococcus granulosus mixed lineage leukemia protein mll 0.0011 0.0016 0.0031
Loa Loa (eye worm) hypothetical protein 0.0006 0.0004 0.0024
Loa Loa (eye worm) MH2 domain-containing protein 0.0127 0.028 0.1879
Schistosoma mansoni biogenic amine (5HT) receptor 0.0034 0.0069 0.0139
Schistosoma mansoni glutamate synthase 0.0006 0.0003 0.0007
Echinococcus granulosus rhodopsin orphan GPCR 0.0034 0.0069 0.0139
Loa Loa (eye worm) hypothetical protein 0.0011 0.0015 0.0099
Trypanosoma cruzi DNA polymerase kappa, putative 0.0006 0.0003 0.0156
Loa Loa (eye worm) hypothetical protein 0.0034 0.0069 0.0465
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.002 0.0036 0.0034
Mycobacterium tuberculosis Conserved hypothetical protein 0.0006 0.0003 0.0001
Brugia malayi RNA recognition motif domain containing protein 0.0133 0.0294 0.1975
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0037 0.0074 0.438
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0014 0.0024 0.1365
Schistosoma mansoni DNA topoisomerase type I 0.0078 0.0169 0.034
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0011 0.0015 0.0084
Onchocerca volvulus 0.0034 0.0069 0.0395
Brugia malayi hypothetical protein 0.0034 0.0069 0.0466
Loa Loa (eye worm) hypothetical protein 0.0034 0.0069 0.0465
Loa Loa (eye worm) hypothetical protein 0.0006 0.0004 0.0024
Trypanosoma cruzi Vps23 core domain containing protein, putative 0.0023 0.0044 0.2562
Trichomonas vaginalis conserved hypothetical protein 0.0005 0.0002 0.0008
Onchocerca volvulus 0.0009 0.001 0.0046
Brugia malayi DNA topoisomerase I 0.0078 0.0169 0.1136
Schistosoma mansoni multidrug resistance protein 0.0011 0.0015 0.003
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0006 0.0003 0.0021
Loa Loa (eye worm) hypothetical protein 0.0034 0.0069 0.0465
Echinococcus multilocularis tar DNA binding protein 0.0133 0.0294 0.0592
Loa Loa (eye worm) hypothetical protein 0.0015 0.0025 0.0167
Brugia malayi jmjC domain containing protein 0.0197 0.044 0.2956
Schistosoma mansoni hypothetical protein 0.0041 0.0085 0.0172
Loa Loa (eye worm) sodium-independent organic anion transporter 0.0013 0.0019 0.013
Trypanosoma brucei glycosyl hydrolase-like protein 0.0015 0.0024 0.1414
Trypanosoma brucei DNA polymerase kappa, putative 0.0006 0.0003 0.0156
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0007 0.0006 0.0039
Echinococcus multilocularis carbonic anhydrase 0.0015 0.0025 0.005
Echinococcus multilocularis lysine specific demethylase 5A 0.0073 0.0157 0.0315
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0034 0.0069 0.0139
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.004 0.0082 0.3903
Schistosoma mansoni smad1 5 8 and 0.0009 0.001 0.0021
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0011 0.0015 0.0084
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0015 0.0025 0.138
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0005 0.0002 0.0004
Echinococcus multilocularis allatostatin A receptor 0.0034 0.0069 0.0139
Loa Loa (eye worm) hypothetical protein 0.0034 0.0069 0.0465
Echinococcus granulosus regulator of G protein signaling 3 0.0005 0.0002 0.0004
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0021 0.0039 0.2289
Schistosoma mansoni glutamate synthase 0.0006 0.0003 0.0007
Loa Loa (eye worm) hypothetical protein 0.0034 0.0069 0.0465
Schistosoma mansoni hypothetical protein 0.0041 0.0085 0.0172
Loa Loa (eye worm) hypothetical protein 0.0015 0.0025 0.0167
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.006 0.0128 0.0257
Schistosoma mansoni neuropeptide receptor 0.0034 0.0069 0.0139
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0006 0.0003 0.0001
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0007 0.0006 0.0012
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0006 0.0003 0.0167
Trichomonas vaginalis maltase-glucoamylase, putative 0.004 0.0082 0.0478
Echinococcus multilocularis organic anion transporting polypeptide 30B 0.0013 0.0019 0.0039
Loa Loa (eye worm) hypothetical protein 0.0019 0.0035 0.0233
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0011 0.0015 0.0084
Schistosoma mansoni hypothetical protein 0.0034 0.0069 0.0139
Trichomonas vaginalis phosphofructokinase, putative 0.0011 0.0016 0.0094
Trichomonas vaginalis ABC transporter, putative 0.0011 0.0015 0.0084
Onchocerca volvulus 0.0013 0.0019 0.01
Schistosoma mansoni hypothetical protein 0.0013 0.0021 0.0043
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0006 0.0003 0.0023
Toxoplasma gondii patched family protein 0.0006 0.0004 0.0137
Loa Loa (eye worm) hypothetical protein 0.0006 0.0004 0.0029
Loa Loa (eye worm) hypothetical protein 0.0034 0.0069 0.0465
Schistosoma mansoni neuropeptide F-like receptor 0.0034 0.0069 0.0139
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0007 0.0006 0.0012
Leishmania major alpha glucosidase II subunit, putative 0.004 0.0082 0.4807
Brugia malayi hypothetical protein 0.0034 0.0069 0.0466
Entamoeba histolytica hypothetical protein 0.0112 0.0247 1
Loa Loa (eye worm) hypothetical protein 0.0011 0.0015 0.0099
Echinococcus granulosus peptide allatostatin:somatostatin 0.0034 0.0069 0.0139
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0048 0.01 0.0589
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0095 0.0207 0.0416
Echinococcus granulosus 5'partial|ATP binding cassette sub family B 0.001 0.0014 0.0029
Loa Loa (eye worm) hypothetical protein 0.0006 0.0004 0.0029
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0021 0.0039 0.2289
Echinococcus multilocularis tumor protein p63 0.0098 0.0214 0.043
Trypanosoma cruzi cysteine peptidase, putative 0.0014 0.0024 0.1365
Schistosoma mansoni steroid hormone receptor ad4bp 0.0007 0.0006 0.0012
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.018 0.0401 0.2694
Brugia malayi hypoxia-induced factor 1 0.0087 0.0189 0.1273
Brugia malayi cytoplasmic intermediate filament protein 0.0007 0.0008 0.0051
Loa Loa (eye worm) carbonic anhydrase 3 0.0015 0.0025 0.0167
Schistosoma mansoni ATP-binding cassette sub-family g2 (white protein) (abcg2) 0.001 0.0013 0.0027
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0034 0.0069 0.0139
Onchocerca volvulus 0.0007 0.0006 0.002
Loa Loa (eye worm) hypothetical protein 0.0115 0.0254 0.1704
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0006 0.0032
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0189 0.0422 0.0849
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0006 0.0032
Echinococcus multilocularis lamin 0.0014 0.0022 0.0045
Brugia malayi hypothetical protein 0.0034 0.0069 0.0466
Schistosoma mansoni cpg binding protein 0.0032 0.0063 0.0127
Schistosoma mansoni aldehyde dehydrogenase 0.0064 0.0137 0.0275
Brugia malayi PHD-finger family protein 0.0021 0.0039 0.0264
Echinococcus multilocularis replication protein A 70 kDa DNA binding 0.001 0.0014 0.0027
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0006 0.0003 0.0167
Loa Loa (eye worm) melatonin receptor type 1A 0.0034 0.0069 0.0465
Echinococcus multilocularis lysine specific demethylase 6a 0.0019 0.0035 0.007
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.002 0.0036 0.0034
Echinococcus multilocularis lamin dm0 0.0014 0.0022 0.0045
Echinococcus granulosus rhodopsin orphan GPCR 0.0034 0.0069 0.0139
Mycobacterium leprae THIOREDOXIN TRXC (TRX) (MPT46) 0.0006 0.0003 0.0001
Echinococcus granulosus ATP binding cassette sub family G 0.001 0.0013 0.0027
Loa Loa (eye worm) hypothetical protein 0.0006 0.0004 0.0029
Loa Loa (eye worm) hypothetical protein 0.01 0.022 0.1475
Toxoplasma gondii PHD-finger domain-containing protein 0.006 0.0128 0.6152
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0007 0.0006 0.0039
Loa Loa (eye worm) hypothetical protein 0.0034 0.0069 0.0465
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.002 0.0036 0.2101
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0007 0.0006 0.0039
Loa Loa (eye worm) hypothetical protein 0.0005 0.0001 0.0009
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0011 0.0016 0.0014
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0019 0.0035 0.162
Loa Loa (eye worm) hypothetical protein 0.0006 0.0004 0.0029
Toxoplasma gondii endonuclease IV APN 0.002 0.0036 0.1681
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0015 0.0025 0.1128
Brugia malayi Serotonin receptor 0.0034 0.0069 0.0466
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0007 0.0006 0.0012
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0014 0.0024 0.1365
Trypanosoma cruzi MFS transporter, putative 0.0013 0.0019 0.1118
Mycobacterium ulcerans thioredoxin reductase TrxB2 0.0006 0.0003 0.0001
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0007 0.0006 0.0039
Schistosoma mansoni ap endonuclease 0.002 0.0036 0.0073
Loa Loa (eye worm) patched family protein 0.0006 0.0004 0.0029
Brugia malayi Patched related family protein 4 0.0006 0.0004 0.003
Brugia malayi Tachykinin-like peptides receptor 99D 0.0034 0.0069 0.0466
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0021 0.0039 0.2289
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0034 0.0069 0.0465
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0034 0.0069 0.0139
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.004 0.0082 0.0548
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0024 0.0045 0.0091
Plasmodium falciparum thioredoxin reductase 0.0062 0.0131 0.7722
Schistosoma mansoni neuropeptide F-like receptor 0.0034 0.0069 0.0139
Brugia malayi MH2 domain containing protein 0.0009 0.001 0.0069
Loa Loa (eye worm) hypothetical protein 0.0006 0.0004 0.0029
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0006 0.0003 0.0076
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0017 0.003 0.006
Loa Loa (eye worm) hypothetical protein 0.0034 0.0069 0.0465
Echinococcus multilocularis sex peptide receptor 0.0034 0.0069 0.0139
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0008 0.0008 0.0017
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0007 0.0006 0.0032
Mycobacterium tuberculosis Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0006 0.0003 0.0001
Brugia malayi intermediate filament protein 0.0014 0.0022 0.015
Trichomonas vaginalis conserved hypothetical protein 0.0005 0.0002 0.0008
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0197 0.044 0.0886
Brugia malayi exodeoxyribonuclease III family protein 0.002 0.0036 0.0242
Onchocerca volvulus 0.0006 0.0004 0.0011
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0005 0.0002 0.0004
Echinococcus granulosus GPCR family 2 0.0033 0.0065 0.0131
Echinococcus multilocularis neutral alpha glucosidase AB 0.004 0.0082 0.0164
Brugia malayi replication factor A 73 kDa subunit 0.001 0.0014 0.0092
Echinococcus multilocularis carbonic anhydrase 0.0015 0.0025 0.005
Echinococcus multilocularis aryl hydrocarbon receptor 0.0007 0.0007 0.0015
Plasmodium falciparum phd finger protein, putative 0.006 0.0128 0.7531
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0007 0.0007 0.0015
Echinococcus multilocularis rhodopsin orphan GPCR 0.0034 0.0069 0.0139
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0007 0.0007 0.0039
Trichomonas vaginalis conserved hypothetical protein 0.0005 0.0002 0.0008
Echinococcus multilocularis sterol regulatory element binding protein 0.0043 0.0089 0.0179
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0037 0.0074 0.0499
Loa Loa (eye worm) hypothetical protein 0.0006 0.0004 0.0029
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0007 0.0006 0.0012
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0024 0.0045 0.0091
Echinococcus granulosus JmjC domain containing protein 4 0.0019 0.0035 0.007
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0083 0.0179 0.0177
Loa Loa (eye worm) hypothetical protein 0.0034 0.0069 0.0465
Echinococcus multilocularis ATP binding cassette sub family G 0.001 0.0013 0.0027
Brugia malayi Melatonin receptor type 1A 0.0034 0.0069 0.0466
Trichomonas vaginalis phosphofructokinase, putative 0.0011 0.0016 0.0094
Loa Loa (eye worm) MH1 domain-containing protein 0.0009 0.001 0.0068
Echinococcus granulosus transcription factor Dp 1 0.001 0.0013 0.0027
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0006 0.0032
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0006 0.0003 0.0007
Mycobacterium ulcerans epoxide hydrolase EphA 0.0046 0.0095 0.0093
Loa Loa (eye worm) patched family protein 0.0006 0.0004 0.0029
Echinococcus multilocularis dro:myosuppressin receptor 0.0034 0.0069 0.0139
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0009 0.001 0.0021
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0021 0.0039 0.2289
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0095 0.0207 0.0416
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0005 0.0002 0.0008
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0021 0.0039 0.0079
Schistosoma mansoni adenoreceptor 0.0034 0.0069 0.0139
Plasmodium falciparum JmjC domain-containing protein, putative 0.0019 0.0035 0.1983
Echinococcus granulosus neuropeptide Y receptor 0.0034 0.0069 0.0139
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0014 0.0024 0.1365
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0034 0.0069 0.0139
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0007 0.0007 0.0039
Schistosoma mansoni smad1 5 8 and 0.0009 0.001 0.0021
Schistosoma mansoni hypothetical protein 0.0006 0.0003 0.0007
Mycobacterium tuberculosis Probable isocitrate lyase AceAa [first part] (isocitrase) (isocitratase) (Icl) 0.4383 1 1
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0015 0.0024 0.0973
Trypanosoma cruzi DNA polymerase kappa, putative 0.0006 0.0003 0.0156
Echinococcus granulosus neuropeptide Y receptor 0.0034 0.0069 0.0139
Schistosoma mansoni alpha-1 adrenergic receptor 0.0034 0.0069 0.0139
Echinococcus multilocularis transcription factor Dp 1 0.001 0.0013 0.0027
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0006 0.0003 0.0001
Plasmodium falciparum topoisomerase I 0.0078 0.0169 1
Trypanosoma brucei NADH dehydrogenase 0.0006 0.0003 0.0167
Brugia malayi Thioredoxin reductase 0.0062 0.0131 0.088
Echinococcus multilocularis rhodopsin orphan GPCR 0.0034 0.0069 0.0139
Toxoplasma gondii LsmAD domain-containing protein 0.0053 0.0113 0.5412
Echinococcus granulosus geminin 0.017 0.0378 0.076
Echinococcus multilocularis ATP binding cassette sub family G 0.001 0.0013 0.0027
Toxoplasma gondii hypothetical protein 0.0006 0.0004 0.0137
Echinococcus granulosus peregrin 0.0064 0.0137 0.0276
Loa Loa (eye worm) hypothetical protein 0.0115 0.0254 0.1704
Loa Loa (eye worm) hypothetical protein 0.0486 0.11 0.7388
Entamoeba histolytica exodeoxyribonuclease III, putative 0.002 0.0036 0.1442
Echinococcus multilocularis multidrug resistance protein 1 0.0011 0.0015 0.003
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0018 0.0105
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.0082 0.4807
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0014 0.0024 0.1365
Trypanosoma cruzi PAB1-binding protein , putative 0.0053 0.0113 0.6644
Loa Loa (eye worm) TAR-binding protein 0.0133 0.0294 0.1975
Echinococcus multilocularis isocitrate dehydrogenase 0.0015 0.0025 0.005
Echinococcus granulosus regulator of G protein signaling 7 0.0005 0.0002 0.0004
Loa Loa (eye worm) hypothetical protein 0.0125 0.0276 0.1851
Echinococcus granulosus FTZ F1 alpha 0.0007 0.0006 0.0012
Brugia malayi regulator of G-protein signaling rgs-7 0.0005 0.0002 0.0013
Echinococcus multilocularis geminin 0.017 0.0378 0.076
Loa Loa (eye worm) patched family protein 0.0006 0.0004 0.0029
Brugia malayi Patched family protein 0.0006 0.0004 0.003
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0006 0.0003 0.0007
Echinococcus multilocularis regulator of G protein signaling 7 0.0005 0.0002 0.0004
Entamoeba histolytica P-glycoprotein-1 0.0011 0.0015 0.0584
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0095 0.0207 0.0416
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0011 0.0015 0.003
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0034 0.0069 0.0139
Echinococcus multilocularis protein patched 0.0043 0.0089 0.0179
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0012 0.0018 0.1054
Brugia malayi isocitrate dehydrogenase 0.0015 0.0025 0.0166
Schistosoma mansoni growth hormone secretagogue receptor 0.0034 0.0069 0.0139
Trichomonas vaginalis glutathione reductase, putative 0.0021 0.0039 0.0228
Loa Loa (eye worm) 6-phosphofructokinase 0.0011 0.0016 0.011
Schistosoma mansoni multidrug resistance protein 0.0011 0.0015 0.003
Loa Loa (eye worm) hypothetical protein 0.0094 0.0206 0.1384
Trypanosoma brucei ABC transporter, putative 0.001 0.0013 0.0751
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.0005 0.0001 0.0002
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0006 0.0032
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0006 0.0003 0.0023
Loa Loa (eye worm) hypothetical protein 0.0013 0.0019 0.013
Loa Loa (eye worm) 6-phosphofructokinase 0.0011 0.0016 0.011
Brugia malayi nuclear hormone receptor 0.0007 0.0006 0.0039
Loa Loa (eye worm) hypothetical protein 0.0034 0.0069 0.0465
Echinococcus multilocularis neuropeptide receptor A26 0.0034 0.0069 0.0139
Trichomonas vaginalis alpha-glucosidase, putative 0.0015 0.0024 0.0141
Schistosoma mansoni glutamate synthase 0.0006 0.0003 0.0007
Toxoplasma gondii patched family protein 0.0006 0.0004 0.0137
Trichomonas vaginalis alpha-glucosidase, putative 0.004 0.0082 0.0478
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0011 0.0015 0.0084
Loa Loa (eye worm) runx1 0.0014 0.0024 0.0158
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0034 0.0069 0.0139
Onchocerca volvulus 0.0034 0.0069 0.0395
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0656 0.1489 1
Entamoeba histolytica acetyltransferase, GNAT family 0.0044 0.0091 0.3684
Brugia malayi MH1 domain containing protein 0.0009 0.001 0.0069
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprB 0.0006 0.0003 0.0001
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0015 0.0024 0.013
Echinococcus multilocularis follistatin 0.0009 0.001 0.0021
Brugia malayi Patched family protein 0.0006 0.0004 0.003
Leishmania major ATP-binding cassette protein subfamily G, member 6, putative 0.001 0.0013 0.0751
Echinococcus granulosus rhodopsin orphan GPCR 0.0034 0.0069 0.0139
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0006 0.0003 0.0121
Trypanosoma brucei ATP-binding cassette protein, putative 0.001 0.0013 0.0751
Echinococcus multilocularis somatostatin receptor 0.0034 0.0069 0.0139
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0006 0.0003 0.009
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0021 0.0039 0.0078
Mycobacterium tuberculosis Probable isocitrate lyase AceAb [second part] (isocitrase) (isocitratase) (Icl) 0.4383 1 1
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.002 0.0036 0.0073
Trichomonas vaginalis replication factor A 1, rfa1, putative 0.0005 0.0002 0.0006
Trypanosoma brucei DNA polymerase eta, putative 0.0006 0.0003 0.0156
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.004 0.0082 0.3292
Loa Loa (eye worm) hypothetical protein 0.0005 0.0002 0.0012
Entamoeba histolytica P-glycoprotein-5 0.0011 0.0015 0.0584
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0007 0.0006 0.0012
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0021 0.0039 0.1833
Trichomonas vaginalis taga, putative 0.0011 0.0015 0.0084
Toxoplasma gondii NADPH-glutathione reductase 0.0021 0.0039 0.1833
Echinococcus granulosus biogenic amine 5HT receptor 0.0034 0.0069 0.0139
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0007 0.0007 0.0039
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0133 0.0294 0.1975
Loa Loa (eye worm) hypothetical protein 0.0007 0.0006 0.0039
Brugia malayi multidrug resistance protein 3 0.0011 0.0015 0.01
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.002 0.0036 0.2101
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0007 0.0006 0.0039
Onchocerca volvulus 0.0021 0.0038 0.021
Brugia malayi PAS domain containing protein 0.0028 0.0055 0.0368
Echinococcus granulosus multidrug resistance protein 1 0.0011 0.0015 0.003
Loa Loa (eye worm) hypothetical protein 0.0034 0.0069 0.0465
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0103 0.0226 0.1517
Onchocerca volvulus 0.0104 0.0228 0.1332
Plasmodium vivax multidrug resistance protein 1, putative 0.0011 0.0015 0.0647
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0007 0.0008 0.0041
Loa Loa (eye worm) hypothetical protein 0.0006 0.0004 0.0029
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0006 0.0003 0.0121
Loa Loa (eye worm) isocitrate dehydrogenase 0.0015 0.0025 0.0166
Leishmania major hypothetical protein, conserved 0.0019 0.0035 0.203
Echinococcus granulosus g protein coupled receptor 0.0034 0.0069 0.0139
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0007 0.0007 0.0392
Echinococcus multilocularis mitogen activated protein kinase 14 0.0037 0.0074 0.015
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0006 0.0003 0.0007
Echinococcus granulosus serotonin receptor 0.0034 0.0069 0.0139
Trypanosoma cruzi hypothetical protein, conserved 0.0012 0.0018 0.1054
Echinococcus multilocularis ecdysone induced protein 78C 0.0007 0.0006 0.0012
Onchocerca volvulus 0.0006 0.0003 0.0006
Loa Loa (eye worm) hypothetical protein 0.0006 0.0003 0.0021
Echinococcus granulosus ATP binding cassette sub family G 0.001 0.0013 0.0027
Trypanosoma cruzi hypothetical protein, conserved 0.0006 0.0003 0.0167
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0034 0.0069 0.0466
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0012 0.0018 0.1054
Onchocerca volvulus 0.0034 0.0069 0.0395
Onchocerca volvulus 0.0034 0.0069 0.0395
Brugia malayi CXXC zinc finger family protein 0.003 0.0059 0.0398
Toxoplasma gondii protease inhibitor PI2 0.0009 0.001 0.0423
Toxoplasma gondii hypothetical protein 0.0015 0.0025 0.114
Loa Loa (eye worm) hypothetical protein 0.0005 0.0002 0.0012
Toxoplasma gondii isocitrate dehydrogenase 0.0015 0.0025 0.1128
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0033 0.0065 0.0131
Onchocerca volvulus 0.0034 0.0069 0.0395
Schistosoma mansoni sulfide quinone reductase 0.0006 0.0003 0.0007
Trypanosoma cruzi NADH dehydrogenase, putative 0.0006 0.0003 0.0167
Entamoeba histolytica P-glyco protein 6, putative 0.0011 0.0015 0.0584
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0011 0.0015 0.0084
Schistosoma mansoni disulfide oxidoreductase 0.0006 0.0003 0.0007
Onchocerca volvulus 0.0034 0.0069 0.0395
Loa Loa (eye worm) hypothetical protein 0.0034 0.0069 0.0465
Schistosoma mansoni neuropeptide receptor 0.0034 0.0069 0.0139
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0006 0.0003 0.0007
Toxoplasma gondii selenide, water dikinase 0.0006 0.0003 0.009
Brugia malayi glutamate synthase 0.0006 0.0003 0.0023
Brugia malayi Patched family protein 0.0006 0.0004 0.003
Schistosoma mansoni neuropeptide receptor 0.0034 0.0069 0.0139
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0006 0.0003 0.0007
Schistosoma mansoni phosphatidylserine receptor 0.0019 0.0035 0.007
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0021 0.0039 0.2289
Brugia malayi ImpB/MucB/SamB family protein 0.0006 0.0003 0.0022
Echinococcus granulosus dnaJ subfamily B 0.0429 0.097 0.1953
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0034 0.0069 0.0466
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0011 0.0015 0.0084
Brugia malayi MH2 domain containing protein 0.0127 0.028 0.188
Echinococcus granulosus tumor protein p63 0.0098 0.0214 0.043
Schistosoma mansoni tar DNA-binding protein 0.0133 0.0294 0.0592
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.002 0.0035 0.2063
Trichomonas vaginalis adenylate cyclase, putative 0.0007 0.0007 0.0039
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0095 0.0207 0.0416
Schistosoma mansoni amine GPCR 0.0034 0.0069 0.0139
Echinococcus multilocularis beta adrenergic receptor kinase 0.0005 0.0002 0.0004
Mycobacterium ulcerans dehydrogenase 0.0006 0.0003 0.0001
Schistosoma mansoni tar DNA-binding protein 0.0133 0.0294 0.0592
Brugia malayi jmjC domain containing protein 0.0019 0.0035 0.0234
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0034 0.0069 0.0465
Onchocerca volvulus 0.0013 0.0019 0.01
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0015 0.0025 0.0168
Echinococcus multilocularis neuropeptide s receptor 0.0034 0.0069 0.0139
Echinococcus granulosus lysosomal alpha glucosidase 0.018 0.0401 0.0807
Mycobacterium ulcerans isocitrate lyase AceAb 0.4383 1 1
Loa Loa (eye worm) hypothetical protein 0.0034 0.0069 0.0465
Schistosoma mansoni microtubule-associated protein tau 0.218 0.4969 1
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0021 0.004 0.2267
Onchocerca volvulus Protein patched homolog 0.0006 0.0004 0.0011
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0007 0.0006 0.0012
Toxoplasma gondii transporter, major facilitator family protein 0.0013 0.0019 0.0871
Mycobacterium ulcerans NADPH dependent 2,4-dienoyl-CoA reductase FadH 0.0006 0.0003 0.0001
Loa Loa (eye worm) hypothetical protein 0.0009 0.001 0.0069
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0015 0.0025 0.143
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0011 0.0015 0.003
Loa Loa (eye worm) programmed cell death 8 0.0006 0.0003 0.0023
Loa Loa (eye worm) hypothetical protein 0.0005 0.0002 0.0012
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0009 0.001 0.0423
Brugia malayi Patched family protein 0.0006 0.0004 0.003
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0006 0.0003 0.0083
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0112 0.0247 0.0497
Brugia malayi steroid hormone receptor 0.0007 0.0006 0.0039
Loa Loa (eye worm) hypothetical protein 0.0034 0.0069 0.0465
Brugia malayi protein C24B5.3 0.0006 0.0004 0.003
Echinococcus granulosus DNA topoisomerase 1 0.0078 0.0169 0.034
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0015 0.0024 0.1414
Mycobacterium tuberculosis Probable NADPH dependent 2,4-dienoyl-CoA reductase FadH (2,4-dienoyl coenzyme A reductase) (4-enoyl-CoA reductase) 0.0006 0.0003 0.0001
Echinococcus granulosus aryl hydrocarbon receptor 0.0007 0.0007 0.0015
Plasmodium vivax hypothetical protein, conserved 0.006 0.0128 0.6152
Leishmania major hypothetical protein, conserved 0.0023 0.0044 0.2562
Leishmania major DNA polymerase eta, putative 0.0006 0.0003 0.0156
Echinococcus multilocularis fmrfamide receptor 0.0034 0.0069 0.0139
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0007 0.0039
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.002 0.0036 0.9115
Echinococcus granulosus glutamate synthase 0.0006 0.0003 0.0007
Schistosoma mansoni alpha-glucosidase 0.0155 0.0344 0.0692
Echinococcus multilocularis carbonic anhydrase 0.0015 0.0025 0.005
Loa Loa (eye worm) hypothetical protein 0.0006 0.0004 0.0029
Onchocerca volvulus Protein patched homolog 0.0006 0.0004 0.0011
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0006 0.0003 0.009
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0011 0.0015 0.0084
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0021 0.0039 0.0037
Onchocerca volvulus 0.0013 0.0019 0.01
Echinococcus granulosus neuropeptides capa receptor 0.0034 0.0069 0.0139
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0012 0.0018 0.1054
Trypanosoma cruzi NADH dehydrogenase, putative 0.0006 0.0003 0.0167
Schistosoma mansoni retinoic acid receptor RXR 0.0007 0.0006 0.0012
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0006 0.0003 0.009
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0006 0.0003 0.0167
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0197 0.044 0.0886
Loa Loa (eye worm) hypothetical protein 0.0013 0.0019 0.013
Loa Loa (eye worm) hypothetical protein 0.0125 0.0276 0.1851
Leishmania major glycosyl hydrolase-like protein 0.0015 0.0024 0.1414
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0007 0.0006 0.0012
Echinococcus granulosus muscleblind protein 0.0486 0.11 0.2214
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0011 0.0016 0.0031
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0006 0.0003 0.0023
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0015 0.0025 0.0167
Leishmania major hypothetical protein, conserved 0.0053 0.0113 0.6644
Loa Loa (eye worm) hypothetical protein 0.0006 0.0004 0.0029
Loa Loa (eye worm) hypothetical protein 0.0006 0.0004 0.0029
Loa Loa (eye worm) hypothetical protein 0.002 0.0036 0.0242
Echinococcus granulosus carbonic anhydrase II 0.0015 0.0025 0.005
Trypanosoma cruzi trypanothione reductase, putative 0.0021 0.0039 0.2289
Mycobacterium leprae PROBABLE NADPH:ADRENODOXIN OXIDOREDUCTASE FPRB (ADRENODOXIN REDUCTASE) (AR) (FERREDOXIN-NADP(+) REDUCTASE) 0.0006 0.0003 0.0001
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0007 0.0007 0.0039
Entamoeba histolytica deoxycytidyl transferase, putative 0.0006 0.0003 0.0113
Brugia malayi Patched related family protein 12 0.0006 0.0004 0.003
Trypanosoma cruzi cysteine peptidase, putative 0.0014 0.0024 0.1365
Trichomonas vaginalis alpha-glucosidase, putative 0.0015 0.0024 0.0141
Plasmodium falciparum carbonic anhydrase 0.0015 0.0025 0.1396
Echinococcus granulosus histone lysine methyltransferase setb 0.0095 0.0207 0.0416
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0034 0.0069 0.0139
Trichomonas vaginalis replication factor A 1, rfa1, putative 0.001 0.0014 0.0077
Trichomonas vaginalis ABC transporter, putative 0.0011 0.0015 0.0084
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0006 0.0003 0.011
Plasmodium vivax SET domain containing protein 0.0008 0.0009 0.0365
Schistosoma mansoni patched 1 0.0043 0.0089 0.0179
Schistosoma mansoni hypothetical protein 0.002 0.0035 0.0071
Brugia malayi hypothetical protein 0.0034 0.0069 0.0466
Echinococcus granulosus Smad4 0.0009 0.001 0.0021
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0006 0.0003 0.0007
Brugia malayi glutathione reductase 0.0062 0.0131 0.088
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0031 0.006 0.0122
Brugia malayi latrophilin 2 splice variant baaae 0.007 0.0151 0.1017
Echinococcus multilocularis axis inhibition protein axin 0.0005 0.0002 0.0004
Brugia malayi hypothetical protein 0.0006 0.0004 0.003
Trichomonas vaginalis abcb9, putative 0.0011 0.0015 0.0084
Loa Loa (eye worm) hypothetical protein 0.0007 0.0006 0.0039
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0014 0.0024 0.1365
Echinococcus multilocularis peregrin 0.0064 0.0137 0.0276
Brugia malayi jmjC domain containing protein 0.0074 0.0161 0.1079
Trypanosoma cruzi DNA polymerase kappa, putative 0.0006 0.0003 0.0156
Loa Loa (eye worm) hypothetical protein 0.0007 0.0007 0.0048
Entamoeba histolytica hypothetical protein 0.0112 0.0247 1
Brugia malayi Nuclear hormone receptor-like 1 0.0007 0.0006 0.0039
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0015 0.0025 0.005
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0112 0.0247 0.0497
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0164 0.0364 0.0733
Schistosoma mansoni opsin-like receptor 0.0034 0.0069 0.0139
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0006 0.0003 0.0017
Echinococcus granulosus expressed conserved protein 0.0094 0.0206 0.0414
Brugia malayi Dopamine receptor protein 2 0.0034 0.0069 0.0466
Brugia malayi hypothetical protein 0.0005 0.0002 0.0013
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0006 0.0032
Schistosoma mansoni hypothetical protein 0.0112 0.0247 0.0497
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0007 0.0006 0.0012
Onchocerca volvulus 0.0747 0.1696 1
Mycobacterium ulcerans NADH dehydrogenase Ndh1 0.0006 0.0003 0.0001
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0013 0.002 0.004
Echinococcus granulosus neuropeptide receptor A26 0.0034 0.0069 0.0139
Brugia malayi hypothetical protein 0.0013 0.0019 0.0131
Echinococcus granulosus fmrfamide receptor 0.0034 0.0069 0.0139
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0011 0.0015 0.0084
Loa Loa (eye worm) hypothetical protein 0.0013 0.0019 0.013
Toxoplasma gondii patched family protein 0.0006 0.0004 0.0137
Brugia malayi Serotonin receptor 0.0034 0.0069 0.0466
Loa Loa (eye worm) hypothetical protein 0.0006 0.0004 0.0029
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0005 0.0002 0.0014
Echinococcus granulosus tar DNA binding protein 0.0133 0.0294 0.0592
Schistosoma mansoni DNA topoisomerase type I 0.0078 0.0169 0.034
Brugia malayi TAR-binding protein 0.0133 0.0294 0.1975
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0007 0.0006 0.0039
Onchocerca volvulus 0.0013 0.0019 0.01
Trypanosoma brucei DNA polymerase IV, putative 0.0006 0.0003 0.0156
Schistosoma mansoni multidrug resistance protein 0.0011 0.0015 0.003
Loa Loa (eye worm) hypothetical protein 0.0009 0.001 0.0069
Toxoplasma gondii aldehyde dehydrogenase 0.0064 0.0137 0.6592
Onchocerca volvulus 0.0034 0.0069 0.0395
Brugia malayi Patched family protein 0.0006 0.0004 0.003
Echinococcus multilocularis ATP binding cassette sub family G 0.001 0.0013 0.0027
Schistosoma mansoni cellular tumor antigen P53 0.0014 0.0023 0.0047
Brugia malayi Patched related family protein 10 0.0006 0.0004 0.003
Brugia malayi Pre-SET motif family protein 0.0656 0.1489 1
Schistosoma mansoni 6-phosphofructokinase 0.0011 0.0016 0.0033
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0007 0.0006 0.0039
Treponema pallidum exodeoxyribonuclease (exoA) 0.002 0.0036 0.9115
Schistosoma mansoni serine/threonine protein kinase 0.0005 0.0002 0.0004
Trichomonas vaginalis replication factor A 1, rfa1, putative 0.001 0.0014 0.0077
Mycobacterium ulcerans DNA polymerase IV 0.0006 0.0003 0.0001
Trypanosoma brucei DNA polymerase kappa, putative 0.0006 0.0003 0.0156
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0006 0.0032
Loa Loa (eye worm) latrophilin receptor protein 2 0.0033 0.0065 0.0436
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0005 0.0002 0.0015
Loa Loa (eye worm) hypothetical protein 0.0034 0.0069 0.0465
Brugia malayi hypothetical protein 0.0112 0.0247 0.166
Plasmodium falciparum ABC transporter G family member 2 0.001 0.0013 0.0697
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0017 0.003 0.1728
Loa Loa (eye worm) hypothetical protein 0.0013 0.0019 0.013
Giardia lamblia Histone acetyltransferase GCN5 0.0044 0.0091 0.7072
Chlamydia trachomatis endonuclease IV 0.002 0.0036 0.9126
Schistosoma mansoni carbonic anhydrase-related 0.0015 0.0025 0.005
Echinococcus granulosus somatostatin receptor 0.0034 0.0069 0.0139
Brugia malayi Patched family protein 0.0006 0.0004 0.003
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0021 0.0039 0.2289
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0006 0.0032
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0009 0.001 0.0423
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0011 0.0015 0.0084
Brugia malayi nuclear receptor NHR-88 0.0007 0.0006 0.0039
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0034 0.0069 0.0466
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0037 0.0074 0.438
Schistosoma mansoni hypothetical protein 0.0033 0.0065 0.0131
Echinococcus multilocularis glutamate synthase 0.0006 0.0003 0.0007
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.002 0.0036 0.2633
Brugia malayi sodium-independent organic anion transporter family protein 0.0013 0.0019 0.0131
Mycobacterium tuberculosis Probable transmembrane multidrug efflux pump 0.0011 0.0015 0.0012
Leishmania major p-glycoprotein 0.0011 0.0015 0.0846
Brugia malayi ORL1-like opioid receptor 0.0034 0.0069 0.0466
Leishmania major cathepsin L-like protease 0.0014 0.0024 0.1365
Brugia malayi Bloom's syndrome protein homolog 0.0008 0.0009 0.0063
Loa Loa (eye worm) hypothetical protein 0.0013 0.0019 0.013
Brugia malayi PHD-finger family protein 0.006 0.0128 0.0858
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.002 0.0035 0.1647
Loa Loa (eye worm) hypothetical protein 0.0007 0.0006 0.0039
Schistosoma mansoni smad 0.0009 0.001 0.0021
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0034 0.0069 0.0139
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0034 0.0069 0.0139
Onchocerca volvulus 0.0006 0.0004 0.0008
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0007 0.0039
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0021 0.0039 0.0079
Giardia lamblia PHD finger protein 15 0.006 0.0128 1
Plasmodium vivax hypothetical protein, conserved 0.0021 0.004 0.1852
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0036 0.0209
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0015 0.0025 0.143
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0034 0.0069 0.0139
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0098 0.0215 0.0212
Schistosoma mansoni smad1 5 8 and 0.0009 0.001 0.0021
Brugia malayi bHLH-PAS transcription factor 0.0021 0.0038 0.0256
Loa Loa (eye worm) CXXC zinc finger family protein 0.003 0.0059 0.0398
Plasmodium vivax ataxin-2 like protein, putative 0.0053 0.0113 0.5412
Loa Loa (eye worm) hypothetical protein 0.0006 0.0004 0.0029
Leishmania major ATP-binding cassette protein subfamily B, member 2, putative 0.0011 0.0015 0.0846
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0036 0.2055
Echinococcus granulosus biogenic amine 5HT receptor 0.0034 0.0069 0.0139
Schistosoma mansoni tsg101-related 0.0061 0.0129 0.026
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0033 0.0065 0.0437
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0083 0.0179 0.0177
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0011 0.0015 0.0084
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0006 0.0003 0.0156
Entamoeba histolytica P-glycoprotein-2 0.0011 0.0015 0.0584
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0007 0.0006 0.0012
Mycobacterium ulcerans hypothetical protein 0.0006 0.0003 0.0001
Echinococcus granulosus alpha 1A adrenergic receptor 0.0034 0.0069 0.0139
Echinococcus granulosus g-protein coupled receptor 0.0034 0.0069 0.0139
Echinococcus multilocularis muscleblind protein 1 0.0486 0.11 0.2214
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0012 0.0018 0.1054
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0021 0.0039 1
Echinococcus multilocularis multidrug resistance protein 1 0.0011 0.0015 0.003
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0006 0.0003 0.0121
Plasmodium vivax thioredoxin reductase, putative 0.0062 0.0131 0.6309
Leishmania major hypothetical protein, conserved 0.0006 0.0003 0.0167
Brugia malayi Regulator of G protein signaling domain containing protein 0.0005 0.0002 0.0013
Trypanosoma cruzi trypanothione reductase, putative 0.0062 0.0131 0.7735
Mycobacterium leprae Probable NADPH:adrenodoxin oxidoreductase FprA (NADPH-FERREDOXIN REDUCTASE) 0.0006 0.0003 0.0001
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0036 0.0209
Loa Loa (eye worm) RecQ helicase 0.0008 0.0009 0.0063
Loa Loa (eye worm) jmjC domain-containing protein 0.0019 0.0035 0.0233
Echinococcus granulosus rhodopsin orphan GPCR 0.0034 0.0069 0.0139
Echinococcus multilocularis expressed protein 0.0009 0.001 0.0021
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.002 0.0036 0.0242
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0015 0.0025 0.005
Echinococcus granulosus thioredoxin glutathione reductase 0.0062 0.0131 0.0264
Loa Loa (eye worm) hypothetical protein 0.0034 0.0069 0.0465
Schistosoma mansoni hypothetical protein 0.0429 0.097 0.1953
Brugia malayi Steroid receptor seven-up type 2 0.0007 0.0006 0.0039
Plasmodium vivax JmjC domain containing protein 0.0019 0.0035 0.162
Plasmodium falciparum thioredoxin reductase 0.0021 0.0039 0.2244
Schistosoma mansoni hypothetical protein 0.0041 0.0085 0.0172
Trypanosoma brucei DNA polymerase IV, putative 0.0006 0.0003 0.0156
Mycobacterium leprae Possible regulatory protein 0.0007 0.0007 0.0005
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0034 0.0069 0.0139
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0009 0.001 0.0021
Echinococcus multilocularis neuropeptide receptor 0.0034 0.0069 0.0139
Entamoeba histolytica hypothetical protein 0.0012 0.0018 0.0727
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0011 0.0015 0.003
Loa Loa (eye worm) hypothetical protein 0.0015 0.0024 0.0164
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0034 0.0069 0.0139
Brugia malayi Putative carbonic anhydrase 5 precursor 0.0015 0.0025 0.0168
Echinococcus multilocularis smad 0.0009 0.001 0.0021
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.0005 0.0003 0.0017
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0011 0.0015 0.0084
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0006 0.0003 0.0007
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0033 0.0065 0.0131
Schistosoma mansoni regulator of G protein signaling 0.0005 0.0002 0.0004
Echinococcus multilocularis Protein lozenge 0.0014 0.0024 0.0047
Entamoeba histolytica disulphide oxidoreductase, putative 0.0006 0.0003 0.0121
Echinococcus granulosus jumonji domain containing 1A 0.0019 0.0035 0.007
Echinococcus granulosus lysine specific demethylase 6a 0.0019 0.0035 0.007
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0017 0.003 0.02
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0083 0.0179 0.0177
Schistosoma mansoni replication factor A 1 rfa1 0.001 0.0014 0.0027
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0034 0.0069 0.0395
Loa Loa (eye worm) hypothetical protein 0.0034 0.0069 0.0465
Leishmania major hypothetical protein, conserved 0.0006 0.0003 0.0167
Echinococcus multilocularis transfer RNA-Lys 0.0021 0.0038 0.0077
Trypanosoma cruzi DNA topoisomerase IB, large subunit, putative 0.0078 0.0169 1
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0018 0.0105
Mycobacterium tuberculosis Probable thioredoxin reductase TrxB2 (TRXR) (TR) 0.0006 0.0003 0.0001
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0006 0.0003 0.0167
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0015 0.0025 0.1446
Trichomonas vaginalis conserved hypothetical protein 0.0005 0.0002 0.0008
Brugia malayi MH2 domain containing protein 0.0009 0.001 0.0069
Brugia malayi Patched family protein 0.0006 0.0004 0.003
Loa Loa (eye worm) hypothetical protein 0.0095 0.0207 0.1388
Schistosoma mansoni tar DNA-binding protein 0.0133 0.0294 0.0592
Echinococcus granulosus phd:f box containing protein 0.0019 0.0035 0.007
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0007 0.0008 0.041
Onchocerca volvulus 0.0034 0.0069 0.0395
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0021 0.0039 1
Brugia malayi hypothetical protein 0.0034 0.0069 0.0466
Mycobacterium ulcerans aldehyde dehydrogenase 0.0064 0.0137 0.0134
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0011 0.0016 0.0031
Mycobacterium ulcerans ferredoxin reductase 0.0006 0.0003 0.0001
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0019 0.0035 0.007
Schistosoma mansoni biogenic amine (5HT) receptor 0.0034 0.0069 0.0139
Loa Loa (eye worm) hypothetical protein 0.0006 0.0004 0.0029
Echinococcus granulosus G protein coupled receptor 139 0.0034 0.0069 0.0139
Loa Loa (eye worm) hypothetical protein 0.0103 0.0226 0.1517
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0006 0.0003 0.0167
Echinococcus granulosus PHD finger protein rhinoceros 0.006 0.0128 0.0257
Loa Loa (eye worm) thioredoxin reductase 0.0062 0.0131 0.0879
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0005 0.0002 0.0004
Trypanosoma cruzi hypothetical protein, conserved 0.0012 0.0018 0.1054
Loa Loa (eye worm) jmjC domain-containing protein 0.0019 0.0035 0.0233
Schistosoma mansoni jumonji domain containing protein 0.0019 0.0035 0.007
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0009 0.001 0.0069
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0021 0.0039 0.0037
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0006 0.0003 0.011
Echinococcus granulosus smad 0.0009 0.001 0.0021
Brugia malayi hypothetical protein 0.0125 0.0276 0.1851
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.0006 0.0032
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0006 0.0003 0.0167
Loa Loa (eye worm) hypothetical protein 0.0006 0.0004 0.0029
Schistosoma mansoni hypothetical protein 0.0034 0.0069 0.0139
Plasmodium falciparum lipid/sterol:H+ symporter 0.0006 0.0004 0.0168
Loa Loa (eye worm) hypothetical protein 0.0034 0.0069 0.0465
Brugia malayi ABC transporter family protein 0.0011 0.0015 0.01
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0017 0.003 0.006
Loa Loa (eye worm) hypothetical protein 0.006 0.0128 0.0858
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0007 0.0006 0.0032
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.01 0.022 0.8885
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0006 0.0032
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0034 0.0069 0.0139
Echinococcus granulosus lamin dm0 0.0014 0.0022 0.0045
Schistosoma mansoni jumonji/arid domain-containing protein 0.0074 0.0161 0.0323
Echinococcus multilocularis G protein coupled receptor 139 0.0034 0.0069 0.0139
Mycobacterium tuberculosis Probable conserved transmembrane ATP-binding protein ABC transporter 0.0008 0.0009 0.0007
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0015 0.0024 0.0141
Echinococcus multilocularis rhodopsin orphan GPCR 0.0034 0.0069 0.0139
Brugia malayi Myosin head containing protein 0.0006 0.0004 0.003
Loa Loa (eye worm) hypothetical protein 0.0006 0.0004 0.0029
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0015 0.0025 0.005
Echinococcus multilocularis mitogen activated protein kinase 11 0.0037 0.0074 0.015
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0021 0.0039 0.0079
Schistosoma mansoni serine/threonine protein kinase 0.0005 0.0002 0.0004
Trichomonas vaginalis abcb9, putative 0.0011 0.0015 0.0084
Echinococcus multilocularis lysosomal alpha glucosidase 0.018 0.0401 0.0807
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0037 0.0074 0.438
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0007 0.0007 0.0392
Trypanosoma brucei DNA polymerase kappa, putative 0.0006 0.0003 0.0156
Loa Loa (eye worm) hypothetical protein 0.0006 0.0004 0.0029
Loa Loa (eye worm) hypothetical protein 0.0006 0.0004 0.0029
Brugia malayi Calcitonin receptor-like protein seb-1 0.0103 0.0226 0.1518
Echinococcus granulosus axis inhibition protein axin 0.0005 0.0002 0.0004
Entamoeba histolytica hypothetical protein 0.0012 0.0018 0.0727
Echinococcus granulosus Niemann Pick C1 protein 0.01 0.022 0.0442
Onchocerca volvulus 0.003 0.0059 0.0336
Giardia lamblia ABC transporter 0.001 0.0013 0.0763
Schistosoma mansoni cpg binding protein 0.0032 0.0063 0.0127
Echinococcus multilocularis rhodopsin orphan GPCR 0.0034 0.0069 0.0139
Echinococcus multilocularis serotonin receptor 0.0034 0.0069 0.0139
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0016 0.0026 0.0177
Treponema pallidum NADH oxidase 0.0021 0.0039 1
Brugia malayi GnHR receptor homolog 0.0034 0.0069 0.0466
Brugia malayi F/Y-rich N-terminus family protein 0.0032 0.0064 0.0432
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.001 0.0013 0.0011
Schistosoma mansoni lozenge 0.0014 0.0024 0.0047
Schistosoma mansoni hypothetical protein 0.017 0.0378 0.076
Echinococcus granulosus lamin 0.0014 0.0022 0.0045
Brugia malayi hypothetical protein 0.0034 0.0069 0.0466
Schistosoma mansoni hypothetical protein 0.0008 0.0009 0.0019
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.004 0.0082 0.0478
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0034 0.0069 0.0139
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.0006 0.0032
Echinococcus multilocularis Solute carrier organic anion transporter family 0.0013 0.0019 0.0039
Echinococcus granulosus single minded 2 0.0021 0.0038 0.0077
Brugia malayi Patched family protein 0.0006 0.0004 0.003
Plasmodium falciparum ataxin-2 like protein, putative 0.0053 0.0113 0.6625
Trichomonas vaginalis phosphofructokinase, putative 0.0011 0.0016 0.0094
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0095 0.0207 1
Entamoeba histolytica hypothetical protein 0.0005 0.0002 0.0059
Onchocerca volvulus Alhambra homolog 0.006 0.0128 0.074
Trichomonas vaginalis mercuric reductase, putative 0.0021 0.0039 0.0228
Onchocerca volvulus Putative organic anion transporter 0.0013 0.0019 0.01
Loa Loa (eye worm) patched family protein 0.0006 0.0004 0.0029
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0021 0.0039 1
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0011 0.0015 0.003
Echinococcus multilocularis muscleblind protein 0.0486 0.11 0.2214
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0007 0.0006 0.0012
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0009 0.001 0.0069
Brugia malayi Glycosyl hydrolases family 31 protein 0.004 0.0082 0.0548
Echinococcus granulosus 6 phosphofructokinase 0.0011 0.0016 0.0033
Echinococcus granulosus multidrug resistance protein 1 0.0007 0.0008 0.0015
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0007 0.0006 0.002
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0015 0.0025 0.0168
Echinococcus multilocularis mitogen activated protein kinase 11 0.0037 0.0074 0.015
Trypanosoma cruzi cysteine peptidase, putative 0.0014 0.0024 0.1365
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0011 0.0015 0.0084
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0005 0.0002 0.0014
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0007 0.0006 0.0012
Plasmodium falciparum multidrug resistance protein 1 0.0011 0.0015 0.0792
Loa Loa (eye worm) hypothetical protein 0.0034 0.0069 0.0465
Loa Loa (eye worm) hypothetical protein 0.0007 0.0006 0.0039
Loa Loa (eye worm) hypothetical protein 0.0005 0.0002 0.0012
Schistosoma mansoni axis inhibition protein axin 0.0005 0.0002 0.0004
Echinococcus multilocularis orexin receptor type 2 0.0034 0.0069 0.0139
Loa Loa (eye worm) hypothetical protein 0.0007 0.0006 0.0039
Loa Loa (eye worm) hypothetical protein 0.0034 0.0069 0.0465
Brugia malayi hypothetical protein 0.0034 0.0069 0.0466
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0017 0.003 0.006
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0014 0.0024 0.1365
Onchocerca volvulus Putative replication factor A 73 kDa subunit 0.0009 0.0011 0.0051
Loa Loa (eye worm) hypothetical protein 0.0006 0.0005 0.0035
Leishmania major carbonic anhydrase-like protein 0.0015 0.0025 0.1446
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0009 0.001 0.0423
Echinococcus multilocularis Regulator of G protein signaling 20 0.0005 0.0002 0.0004
Mycobacterium tuberculosis Probable dehydrogenase 0.0083 0.0179 0.0177
Schistosoma mansoni biogenic amine receptor 0.0034 0.0069 0.0139
Loa Loa (eye worm) hypothetical protein 0.0034 0.0069 0.0465
Echinococcus granulosus g protein coupled receptor 0.0034 0.0069 0.0139
Echinococcus multilocularis musashi 0.0014 0.0022 0.0045
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0021 0.0039 0.0263
Trypanosoma brucei carbonic anhydrase-like protein 0.0015 0.0025 0.1446
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0011 0.0015 0.0084
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.004 0.0082 0.0478
Trichomonas vaginalis helicase, putative 0.0007 0.0006 0.0032
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0037 0.0074 0.438
Plasmodium falciparum ataxin-2 like protein, putative 0.0053 0.0113 0.6625
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.002 0.0035 0.2063
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0006 0.0003 0.0007
Brugia malayi A-kinase anchor protein 10, precursor 0.0005 0.0002 0.0013
Brugia malayi Patched protein homolog 1 0.0006 0.0004 0.003
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0012 0.0018 0.1054
Chlamydia trachomatis ABC transporter ATP binding protein/permease 0.0011 0.0015 0.3198
Echinococcus multilocularis dna polymerase kappa 0.0006 0.0003 0.0007
Echinococcus granulosus lysine specific demethylase 5A 0.0074 0.0161 0.0323
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0011 0.0015 0.0084
Plasmodium vivax patched family protein, putative 0.0006 0.0004 0.0137
Loa Loa (eye worm) hypothetical protein 0.0034 0.0069 0.0465
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0164 0.0364 0.0733
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0006 0.0003 0.0121
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0009 0.001 0.0069
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0007 0.0006 0.0012
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0012 0.0018 0.1054
Entamoeba histolytica hypothetical protein 0.0005 0.0002 0.0059
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0015 0.0024 0.0141
Mycobacterium ulcerans 6-phosphofructokinase 0.0011 0.0016 0.0014
Echinococcus granulosus mitogen activated protein kinase 14 0.0037 0.0074 0.015
Leishmania major replication factor A, 51kDa subunit, putative 0.0005 0.0002 0.0058
Loa Loa (eye worm) patched family protein 0.0006 0.0004 0.0029
Schistosoma mansoni Smad4 0.0009 0.001 0.0021
Onchocerca volvulus 0.0115 0.0254 0.1484
Onchocerca volvulus 0.0013 0.0019 0.01
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0006 0.0003 0.0007
Toxoplasma gondii exonuclease III APE 0.002 0.0036 0.1679
Echinococcus granulosus neuropeptide FF receptor 2 0.0034 0.0069 0.0139
Schistosoma mansoni neuropeptide receptor 0.0034 0.0069 0.0139
Loa Loa (eye worm) G-protein coupled receptor 0.0034 0.0069 0.0465
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.0082 0.4807
Loa Loa (eye worm) glutathione reductase 0.0062 0.0131 0.0879
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0011 0.0015 0.0084
Brugia malayi hypothetical protein 0.0006 0.0004 0.003
Loa Loa (eye worm) hypothetical protein 0.0034 0.0069 0.0465
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0067 0.0144 0.029
Brugia malayi MH1 domain containing protein 0.0005 0.0001 0.001
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0011 0.0015 0.0084
Loa Loa (eye worm) hypothetical protein 0.0034 0.0069 0.0465
Trichomonas vaginalis DNA helicase recq, putative 0.0008 0.0009 0.0052
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0006 0.0003 0.0007
Brugia malayi sulfakinin receptor protein 0.0034 0.0069 0.0466
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0007 0.0006 0.0039
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0021 0.0039 0.2289
Echinococcus multilocularis g-protein coupled receptor 0.0034 0.0069 0.0139
Schistosoma mansoni bromodomain containing protein 0.0006 0.0004 0.0007
Trichomonas vaginalis maltase-glucoamylase, putative 0.0015 0.0024 0.0141
Schistosoma mansoni zinc finger protein 0.0006 0.0004 0.0007
Echinococcus granulosus Niemann Pick C1 protein 0.0143 0.0318 0.064
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0007 0.0006 0.0039
Leishmania major protein kinase, putative 0.0007 0.0008 0.041
Loa Loa (eye worm) kazal-type serine protease inhibitor domain-containing protein 0.0009 0.001 0.0069
Schistosoma mansoni hypothetical protein 0.0024 0.0045 0.0091
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0006 0.0003 0.0167
Entamoeba histolytica hypothetical protein 0.0012 0.0018 0.0727
Echinococcus granulosus Protein patched homolog 1 0.0043 0.0089 0.0179
Brugia malayi putative neuropeptide receptor 0.0034 0.0069 0.0466
Echinococcus granulosus organic anion transporting polypeptide 30B 0.0013 0.0019 0.0039
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.0005 0.0001 0.0002
Echinococcus multilocularis fmrfamide receptor 0.0034 0.0069 0.0139
Brugia malayi larval opioid receptor 0.0034 0.0069 0.0466
Brugia malayi protein C24B5.3 0.0006 0.0004 0.003
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0007 0.0008 0.041
Echinococcus granulosus neuropeptide receptor 0.0034 0.0069 0.0139
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0006 0.0003 0.0017
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0015 0.0025 0.143
Echinococcus multilocularis lysosomal alpha glucosidase 0.018 0.0401 0.0807
Echinococcus multilocularis jumonji domain containing protein 0.0084 0.0182 0.0365
Echinococcus multilocularis Niemann Pick C1 protein 0.0143 0.0318 0.064
Loa Loa (eye worm) nuclear factor I 0.0005 0.0001 0.0009
Echinococcus granulosus allatostatin A receptor 0.0034 0.0069 0.0139
Loa Loa (eye worm) hypothetical protein 0.0006 0.0003 0.0023
Schistosoma mansoni ap endonuclease 0.002 0.0036 0.0073
Echinococcus granulosus mitogen activated protein kinase 11 0.0037 0.0074 0.015
Echinococcus multilocularis JmjC domain containing protein 4 0.0019 0.0035 0.007
Brugia malayi PHD-finger family protein 0.0006 0.0004 0.0024
Loa Loa (eye worm) hypothetical protein 0.0006 0.0004 0.0029
Brugia malayi PXA domain containing protein 0.0005 0.0002 0.0013
Echinococcus granulosus multidrug resistance protein 1 0.0007 0.0008 0.0015
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0019 0.0035 0.162
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0017 0.003 0.1728
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0011 0.0015 0.0084
Schistosoma mansoni lamin 0.0014 0.0022 0.0045
Loa Loa (eye worm) hypothetical protein 0.0034 0.0069 0.0465
Echinococcus granulosus tumor susceptibility gene 101 protein 0.0073 0.0157 0.0316
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0007 0.0006 0.0039
Mycobacterium ulcerans putative regulatory protein 0.0021 0.0038 0.0036
Schistosoma mansoni myosin xvIII 0.0034 0.0069 0.0139
Schistosoma mansoni carbonic anhydrase-related 0.0015 0.0025 0.005
Echinococcus granulosus jumonji domain containing protein 0.0084 0.0182 0.0365
Onchocerca volvulus Putative organic anion transporter 0.0013 0.0019 0.01
Trichomonas vaginalis DNA helicase recq1, putative 0.0008 0.0009 0.0052
Schistosoma mansoni smdr2 0.0011 0.0015 0.003
Echinococcus multilocularis regulator of G protein signaling 3 0.0005 0.0002 0.0004
Mycobacterium tuberculosis Probable oxidoreductase 0.0098 0.0215 0.0212
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0007 0.0006 0.0039
Onchocerca volvulus 0.0006 0.0004 0.0011
Schistosoma mansoni axis inhibition protein axin 0.0005 0.0002 0.0004
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0011 0.0015 0.003
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0015 0.0025 0.143
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0034 0.0069 0.0139
Loa Loa (eye worm) hypothetical protein 0.0007 0.0006 0.0037
Echinococcus granulosus tm gpcr rhodopsin 0.0034 0.0069 0.0139
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0034 0.0069 0.0139
Brugia malayi AF-10 protein 0.002 0.0035 0.0238
Loa Loa (eye worm) hypothetical protein 0.0005 0.0003 0.0016
Echinococcus granulosus orexin receptor type 2 0.0034 0.0069 0.0139
Brugia malayi ecdysteroid receptor 0.0007 0.0006 0.0039
Schistosoma mansoni serine/threonine protein kinase 0.0005 0.0002 0.0004
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0011 0.0015 0.0084
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0006 0.0004 0.0007
Schistosoma mansoni hypothetical protein 0.0041 0.0085 0.0172
Trypanosoma brucei PAB1-binding protein , putative 0.0053 0.0113 0.6644
Trichomonas vaginalis abcb9, putative 0.0011 0.0015 0.0084
Loa Loa (eye worm) hypothetical protein 0.0006 0.0004 0.0029
Trichomonas vaginalis phosphofructokinase, putative 0.0011 0.0016 0.0094
Onchocerca volvulus 0.0095 0.0207 0.1206
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0034 0.0069 0.0139
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0034 0.0069 0.0139
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0021 0.0039 0.2289
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0021 0.0039 0.2289
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0007 0.0006 0.0039
Schistosoma mansoni tsg101-related 0.0061 0.0129 0.026
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0007 0.0007 0.033
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0064 0.0137 0.0134
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0015 0.0024 0.1414
Echinococcus granulosus carbonic anhydrase 0.0015 0.0025 0.005
Entamoeba histolytica hypothetical protein 0.0005 0.0002 0.0059
Toxoplasma gondii histone lysine methyltransferase SET1 0.0065 0.0138 0.6647
Echinococcus multilocularis rhodopsin orphan GPCR 0.0034 0.0069 0.0139
Brugia malayi Bromodomain containing protein 0.0006 0.0004 0.0024
Brugia malayi small heat shock protein 0.0181 0.0405 0.272
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0011 0.0015 0.003
Brugia malayi Patched family protein 0.0006 0.0004 0.003
Brugia malayi putative neuropeptide receptor NPR1 0.0034 0.0069 0.0466
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.002 0.0036 0.1681
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0015 0.0025 0.1446
Entamoeba histolytica tumor susceptibility gene 101 protein, putative 0.005 0.0104 0.4192
Echinococcus granulosus intermediate filament protein 0.0014 0.0022 0.0045
Brugia malayi Smad1 0.0009 0.001 0.0069
Echinococcus multilocularis microtubule associated protein 2 0.218 0.4969 1
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0011 0.0015 0.0084
Trichomonas vaginalis ABC transporter, putative 0.0011 0.0015 0.0084
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0006 0.0003 0.0017
Leishmania major DNA polymerase kappa, putative 0.0006 0.0003 0.0156
Brugia malayi Glycosyl hydrolases family 31 protein 0.0015 0.0024 0.0164
Echinococcus granulosus agrin 0.0009 0.001 0.0021
Brugia malayi Patched family protein 0.0006 0.0004 0.003
Loa Loa (eye worm) hypothetical protein 0.0053 0.0111 0.0745
Brugia malayi sodium-independent organic anion transporter family protein 0.0013 0.0019 0.0131
Entamoeba histolytica hypothetical protein 0.0012 0.0018 0.0727
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0006 0.0003 0.0017
Trypanosoma cruzi cruzipain precursor, putative 0.0014 0.0024 0.1365
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0006 0.0003 0.009
Echinococcus granulosus 7TM GPCR rhodopsin 0.0034 0.0069 0.0139
Toxoplasma gondii isocitrate dehydrogenase 0.0015 0.0025 0.1128
Echinococcus granulosus rhodopsin orphan GPCR 0.0034 0.0069 0.0139
Loa Loa (eye worm) hypothetical protein 0.001 0.0014 0.0096
Loa Loa (eye worm) DNA topoisomerase I 0.0078 0.0169 0.1136
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0259 0.0583 0.3914
Brugia malayi 6-phosphofructokinase 0.0011 0.0016 0.0111
Trichomonas vaginalis hypothetical protein 0.0036 0.0072 0.0419
Schistosoma mansoni intermediate filament proteins 0.0014 0.0022 0.0045
Echinococcus multilocularis 6 phosphofructokinase 0.0011 0.0016 0.0033
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0007 0.0007 0.0039
Schistosoma mansoni alpha glucosidase 0.004 0.0082 0.0164
Leishmania major hypothetical protein, conserved 0.0006 0.0003 0.0167
Echinococcus multilocularis cpg binding protein 0.0032 0.0063 0.0127
Brugia malayi Patched family protein 0.0006 0.0004 0.003
Onchocerca volvulus Putative organic anion transporter 0.0013 0.0019 0.01
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0161 0.0358 0.2402
Entamoeba histolytica P-glycoprotein-2, putative 0.0011 0.0015 0.0584
Plasmodium vivax glutathione reductase, putative 0.0062 0.0131 0.6309
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0006 0.0003 0.0167
Brugia malayi hypothetical protein 0.0115 0.0254 0.1705
Loa Loa (eye worm) hypothetical protein 0.0006 0.0004 0.0029
Schistosoma mansoni aryl hydrocarbon receptor 0.0028 0.0055 0.011
Entamoeba histolytica ABC transporter, putative 0.001 0.0013 0.052
Schistosoma mansoni regulator of G protein signaling 0.0005 0.0002 0.0004
Onchocerca volvulus 0.0007 0.0007 0.0028
Echinococcus granulosus rhodopsin orphan GPCR 0.0034 0.0069 0.0139
Brugia malayi Pre-SET motif family protein 0.0095 0.0207 0.1388
Schistosoma mansoni hypothetical protein 0.017 0.0378 0.076
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0034 0.0069 0.0466
Leishmania major cathepsin L-like protease 0.0014 0.0024 0.1365
Echinococcus multilocularis bloom syndrome protein 0.0008 0.0009 0.0019
Brugia malayi RE15519p 0.0034 0.0069 0.0466
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0089 0.052
Loa Loa (eye worm) hypothetical protein 0.0019 0.0035 0.0233
Trypanosoma brucei Vps23 core domain containing protein, putative 0.0023 0.0044 0.2562
Echinococcus multilocularis expressed conserved protein 0.0094 0.0206 0.0414
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0012 0.0018 0.1054
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0021 0.0039 0.2289
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0007 0.0006 0.0039
Mycobacterium leprae Isocitrate lyase 0.2055 0.4682 0.4681
Echinococcus multilocularis mothers against decapentaplegic 5 0.0009 0.001 0.0021
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0012 0.0018 0.1054
Entamoeba histolytica hypothetical protein 0.0112 0.0247 1
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0102 0.0223 0.0449
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0007 0.0007 0.0392
Loa Loa (eye worm) hypothetical protein 0.0034 0.0069 0.0465
Echinococcus multilocularis phd:f box containing protein 0.0019 0.0035 0.007
Echinococcus multilocularis regulator of G protein signaling 7 0.0005 0.0002 0.0004
Toxoplasma gondii ATP-binding cassette G family transporter ABCG84 0.001 0.0013 0.0569
Brugia malayi Dopamine receptor 0.0034 0.0069 0.0466
Loa Loa (eye worm) jmjC domain-containing protein 0.0074 0.0161 0.1078
Loa Loa (eye worm) hypothetical protein 0.0006 0.0004 0.0029
Schistosoma mansoni lamin 0.0014 0.0022 0.0045
Trypanosoma brucei DNA polymerase kappa, putative 0.0006 0.0003 0.0156
Trichomonas vaginalis guanylate cyclase, putative 0.0007 0.0007 0.0039
Mycobacterium ulcerans DNA polymerase IV 0.0006 0.0003 0.0001
Brugia malayi ImpB/MucB/SamB family protein 0.0006 0.0003 0.0022
Mycobacterium tuberculosis Probable NADPH:adrenodoxin oxidoreductase FprB (adrenodoxin reductase) (AR) (ferredoxin-NADP(+) reductase) 0.0006 0.0003 0.0001
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0062 0.0131 0.0129
Onchocerca volvulus 0.0034 0.0069 0.0395
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.0006 0.0032
Trypanosoma cruzi DNA polymerase eta, putative 0.0006 0.0003 0.0156
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0006 0.0003 0.0017
Loa Loa (eye worm) G-protein coupled receptor 0.0034 0.0069 0.0465
Loa Loa (eye worm) hypothetical protein 0.0005 0.0002 0.0012
Brugia malayi Bromodomain containing protein 0.0064 0.0137 0.092
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0007 0.0006 0.0039
Brugia malayi neuropeptide F receptor 0.0034 0.0069 0.0466
Schistosoma mansoni amine GPCR 0.0034 0.0069 0.0139
Schistosoma mansoni hypothetical protein 0.0034 0.0069 0.0139
Mycobacterium leprae Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0006 0.0003 0.0001
Loa Loa (eye worm) hypothetical protein 0.0005 0.0002 0.0012
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0098 0.0215 0.0212
Schistosoma mansoni blooms syndrome DNA helicase 0.0007 0.0005 0.0011
Schistosoma mansoni cpg binding protein 0.003 0.0059 0.0119
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0015 0.0025 0.0168
Brugia malayi hypothetical protein 0.0005 0.0002 0.0013
Brugia malayi Muscleblind-like protein 0.0486 0.11 0.7389
Brugia malayi follicle stimulating hormone receptor 0.0161 0.0358 0.2402
Plasmodium vivax SET domain protein, putative 0.0095 0.0207 1
Loa Loa (eye worm) hypothetical protein 0.0486 0.11 0.7388
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0007 0.0039
Trichomonas vaginalis alpha-glucosidase, putative 0.004 0.0082 0.0478
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0034 0.0069 0.0466
Schistosoma mansoni protein phosphatase 2C 0.0019 0.0035 0.007
Echinococcus multilocularis zinc finger protein 0.0006 0.0004 0.0007
Loa Loa (eye worm) hypothetical protein 0.0034 0.0069 0.0465
Schistosoma mansoni regulator of G protein signaling 0.0005 0.0002 0.0004
Mycobacterium ulcerans NADH dehydrogenase 0.0006 0.0003 0.0001
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0006 0.0003 0.0017
Trypanosoma brucei trypanothione reductase 0.0062 0.0131 0.7735
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0048 0.01 0.4821
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0034 0.0069 0.0139
Loa Loa (eye worm) RGS-3 protein 0.0005 0.0002 0.0012
Onchocerca volvulus 0.0014 0.0022 0.0117
Mycobacterium ulcerans endonuclease IV 0.002 0.0036 0.0034
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0019 0.0035 0.203
Trichomonas vaginalis glutamate synthase, putative 0.0006 0.0003 0.0017
Onchocerca volvulus 0.0006 0.0004 0.0011
Loa Loa (eye worm) hypothetical protein 0.0034 0.0069 0.0465
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0006 0.0003 0.0007
Onchocerca volvulus Huntingtin homolog 0.0125 0.0276 0.1613
Schistosoma mansoni alpha-glucosidase 0.0155 0.0344 0.0692
Schistosoma mansoni histamine h1 receptor 0.0034 0.0069 0.0139
Mycobacterium tuberculosis Possible dehydrogenase/reductase 0.0006 0.0003 0.0001
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0006 0.0003 0.0167
Echinococcus multilocularis mitogen activated protein kinase 14 0.0037 0.0074 0.015
Onchocerca volvulus 0.0034 0.0069 0.0395
Loa Loa (eye worm) hypothetical protein 0.0014 0.0022 0.015
Entamoeba histolytica phosphofructokinase, putative 0.0011 0.0016 0.065
Brugia malayi Intermediate filament tail domain containing protein 0.0014 0.0022 0.015
Brugia malayi PXA domain containing protein 0.0005 0.0002 0.0013
Trypanosoma brucei hypothetical protein, conserved 0.0006 0.0003 0.0167
Echinococcus granulosus tachykinin peptides receptor 99D 0.0034 0.0069 0.0139
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0011 0.0015 0.003
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0017 0.003 0.1728
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0034 0.0069 0.0139
Loa Loa (eye worm) hypothetical protein 0.0007 0.0006 0.0039
Echinococcus multilocularis g protein coupled receptor 0.0034 0.0069 0.0139
Brugia malayi Protein kinase domain containing protein 0.0004 0 0.0002
Loa Loa (eye worm) hypothetical protein 0.0053 0.0113 0.0756
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0034 0.0069 0.0139
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0034 0.0069 0.0139
Loa Loa (eye worm) acetyltransferase 0.0164 0.0364 0.2448
Loa Loa (eye worm) hypothetical protein 0.0181 0.0405 0.2719
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0095 0.0207 0.0416
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0014 0.0024 0.1365
Loa Loa (eye worm) hypothetical protein 0.0009 0.001 0.0069
Loa Loa (eye worm) hypoxia-induced factor 1 0.0087 0.0189 0.1272
Echinococcus granulosus Regulator of G protein signaling 20 0.0005 0.0002 0.0004
Schistosoma mansoni biogenic amine receptor 0.0034 0.0069 0.0139
Schistosoma mansoni hypothetical protein 0.0034 0.0069 0.0139
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0015 0.0025 0.143
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.0006 0.0032
Brugia malayi hypothetical protein 0.0034 0.0069 0.0466
Echinococcus granulosus neuropeptide receptor 0.0034 0.0069 0.0139
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0006 0.0004 0.0007
Schistosoma mansoni 6-phosphofructokinase 0.0011 0.0016 0.0033
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0007 0.0008 0.041
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0013 0.0021 0.1195
Trypanosoma cruzi Replication factor A protein 1 0.0005 0.0002 0.0058
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0021 0.0039 0.2289
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0011 0.0015 0.0647
Loa Loa (eye worm) PHD-finger family protein 0.006 0.0128 0.0858
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0021 0.0039 0.2289
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0011 0.0015 0.0084
Onchocerca volvulus 0.0014 0.0022 0.0117
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0048 0.01 0.4821
Echinococcus multilocularis neuropeptide receptor 0.0034 0.0069 0.0139
Echinococcus granulosus cpg binding protein 0.0032 0.0063 0.0127
Leishmania major ATP-dependent phosphofructokinase 0.0011 0.0016 0.0942
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0019 0.0035 0.203
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0007 0.0008 0.005
Echinococcus multilocularis thyroid hormone receptor alpha 0.0007 0.0006 0.0012
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0014 0.0024 0.1365
Echinococcus granulosus dna polymerase eta 0.0006 0.0003 0.0007
Brugia malayi 6-phosphofructokinase 0.0012 0.0017 0.0114
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0021 0.0039 0.2289
Trypanosoma brucei DNA polymerase kappa, putative 0.0006 0.0003 0.0156
Brugia malayi Dopamine receptor protein 1 0.0034 0.0069 0.0466
Loa Loa (eye worm) ABC transporter 0.0008 0.001 0.0066
Schistosoma mansoni bromodomain containing protein 0.0006 0.0004 0.0007
Echinococcus granulosus beta-adrenergic receptor kinase 0.0005 0.0002 0.0004
Plasmodium falciparum glutathione reductase 0.0021 0.0039 0.2244
Echinococcus multilocularis Smad4 0.0009 0.001 0.0021
Entamoeba histolytica phosphofructokinase, putative 0.0011 0.0016 0.065
Mycobacterium ulcerans aldehyde dehydrogenase 0.0064 0.0137 0.0134
Loa Loa (eye worm) hypothetical protein 0.0259 0.0583 0.3914
Loa Loa (eye worm) hypothetical protein 0.0006 0.0004 0.0029
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0006 0.0003 0.0017
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0095 0.0207 0.0416
Loa Loa (eye worm) neuropeptide F receptor 0.0034 0.0069 0.0465
Schistosoma mansoni ABC transporter 0.0008 0.001 0.002
Brugia malayi G protein-coupled receptor F59B2.13 0.0034 0.0069 0.0466
Loa Loa (eye worm) PXA domain-containing protein 0.0005 0.0002 0.0012
Schistosoma mansoni opsin-like receptor 0.0034 0.0069 0.0139
Entamoeba histolytica recQ family helicase, putative 0.0004 0.0001 0.0006
Echinococcus multilocularis G-protein coupled receptor, putative 0.0034 0.0069 0.0139
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0034 0.0069 0.0139
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0021 0.0039 0.0078
Loa Loa (eye worm) hypothetical protein 0.0034 0.0069 0.0465
Loa Loa (eye worm) hypothetical protein 0.0015 0.0025 0.0167
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0034 0.0069 0.0139
Mycobacterium ulcerans glutamate synthase subunit beta 0.0006 0.0003 0.0001
Toxoplasma gondii ATP-binding cassette transporter ABC.B1 0.0011 0.0015 0.0647
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.002 0.0036 0.0073
Loa Loa (eye worm) hypothetical protein 0.0034 0.0069 0.0465
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0034 0.0069 0.0139
Plasmodium vivax ABC transporter G family member 2, putative 0.001 0.0013 0.0569
Schistosoma mansoni thyroid hormone receptor 0.0007 0.0006 0.0012
Trypanosoma brucei UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0012 0.0018 0.1054
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0048 0.01 0.4821
Schistosoma mansoni regulator of G protein signaling 0.0005 0.0002 0.0004
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0009 0.001 0.0069
Loa Loa (eye worm) hypothetical protein 0.0007 0.0006 0.0039
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0083 0.0179 0.0177
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0007 0.0006 0.0039
Echinococcus granulosus ATP binding cassette sub family G 0.001 0.0013 0.0027
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0007 0.0006 0.0039
Leishmania major NADH dehydrogenase, putative 0.0006 0.0003 0.0167
Schistosoma mansoni sulfide quinone reductase 0.0006 0.0003 0.0007
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0006 0.0003 0.0017
Trichomonas vaginalis DNA polymerase eta, putative 0.0006 0.0003 0.0015
Trypanosoma cruzi PAB1-binding protein , putative 0.0053 0.0113 0.6644
Loa Loa (eye worm) hypothetical protein 0.007 0.0151 0.1017
Echinococcus granulosus g protein coupled receptor 0.0034 0.0069 0.0139
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0007 0.0006 0.0039
Loa Loa (eye worm) hypothetical protein 0.0034 0.0069 0.0465
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0006 0.0003 0.0023
Loa Loa (eye worm) hypothetical protein 0.0014 0.0022 0.0146
Trypanosoma brucei Replication factor A protein 1 0.0005 0.0002 0.0058
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0007 0.0006 0.0012
Trichomonas vaginalis bromodomain-containing protein, putative 0.0048 0.01 0.0589
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0021 0.0039 0.0079
Loa Loa (eye worm) hypothetical protein 0.0013 0.0019 0.013
Schistosoma mansoni coup transcription factor 0.0007 0.0006 0.0012
Echinococcus multilocularis neuropeptides capa receptor 0.0034 0.0069 0.0139
Loa Loa (eye worm) hypothetical protein 0.0006 0.0004 0.0029
Schistosoma mansoni amine GPCR 0.0034 0.0069 0.0139
Brugia malayi MH1 domain containing protein 0.0005 0.0001 0.001
Loa Loa (eye worm) hypothetical protein 0.0034 0.0069 0.0465
Brugia malayi photoreceptor-specific nuclear receptor 0.0007 0.0006 0.0039
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0017 0.003 0.1188
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0015 0.0025 0.0167
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0006 0.0003 0.0167
Echinococcus granulosus neuropeptides capa receptor 0.0034 0.0069 0.0139
Echinococcus granulosus carbonic anhydrase 0.0015 0.0025 0.005
Loa Loa (eye worm) hypothetical protein 0.0006 0.0005 0.0035
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0015 0.0025 0.005
Loa Loa (eye worm) hypothetical protein 0.0006 0.0004 0.0029
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0189 0.0422 0.0849
Trichomonas vaginalis alpha-glucosidase, putative 0.004 0.0082 0.0478
Loa Loa (eye worm) Smad1 0.0009 0.001 0.0068
Echinococcus multilocularis neuropeptides capa receptor 0.0034 0.0069 0.0139
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.002 0.0036 0.2101
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0021 0.0039 0.0037
Schistosoma mansoni jumonji/arid domain-containing protein 0.0074 0.0161 0.0323
Onchocerca volvulus 0.0034 0.0069 0.0395
Loa Loa (eye worm) hypothetical protein 0.0006 0.0004 0.0029
Trypanosoma brucei DNA polymerase kappa, putative 0.0006 0.0003 0.0156
Brugia malayi G-protein coupled receptor 0.0034 0.0069 0.0466
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.002 0.0036 0.0034
Brugia malayi G-protein coupled receptor 0.0034 0.0069 0.0466
Entamoeba histolytica P-glycoprotein 5, putative 0.0011 0.0015 0.0584
Echinococcus multilocularis jumonji domain containing 1A 0.0019 0.0035 0.007
Brugia malayi Latrophilin receptor protein 2 0.0033 0.0065 0.0437
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0034 0.0069 0.0139
Echinococcus multilocularis neuropeptide Y receptor 0.0034 0.0069 0.0139
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0015 0.0025 0.0168
Leishmania major cathepsin L-like protease 0.0014 0.0024 0.1365
Onchocerca volvulus 0.0006 0.0004 0.0011
Echinococcus multilocularis regulator of G protein signaling 3 0.0005 0.0002 0.0004
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0007 0.0007 0.1058
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0015 0.0025 0.0168
Loa Loa (eye worm) MH2 domain-containing protein 0.0009 0.001 0.0068
Echinococcus granulosus dna polymerase kappa 0.0006 0.0003 0.0007
Schistosoma mansoni transcription factor LCR-F1 0.0112 0.0247 0.0497
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0064 0.0137 0.0275
Echinococcus granulosus follistatin 0.0009 0.001 0.0021
Echinococcus granulosus expressed protein 0.0097 0.0212 0.0427
Trichomonas vaginalis alpha-glucosidase, putative 0.004 0.0082 0.0478
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.002 0.0036 0.2057
Onchocerca volvulus Neuropeptide F receptor homolog 0.0034 0.0069 0.0395
Echinococcus multilocularis axis inhibition protein axin 0.0005 0.0002 0.0004
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0083 0.0179 0.0177
Leishmania major ATP-binding cassette protein subfamily G, member 4, putative 0.001 0.0013 0.0751
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.002 0.0036 0.2101
Brugia malayi AKH receptor 0.0034 0.0069 0.0466
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.001 0.0013 0.0011
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0017 0.003 0.1728
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0006 0.0003 0.0167
Echinococcus multilocularis ATP binding cassette sub family B 0.001 0.0014 0.0029
Plasmodium vivax ferrodoxin reductase, putative 0.0006 0.0003 0.009
Brugia malayi MH1 domain containing protein 0.0009 0.001 0.0069
Brugia malayi CHE-14 protein 0.0043 0.0089 0.0597
Loa Loa (eye worm) replication factor A 73 kDa subunit 0.001 0.0014 0.0091
Schistosoma mansoni hypothetical protein 0.0015 0.0025 0.005
Toxoplasma gondii thioredoxin reductase 0.0062 0.0131 0.6309
Brugia malayi neuropeptide F receptor 0.0034 0.0069 0.0466
Entamoeba histolytica P-glycoprotein-2 0.0011 0.0015 0.0584
Brugia malayi hypothetical protein 0.0094 0.0206 0.1385
Echinococcus granulosus neutral alpha glucosidase AB 0.004 0.0082 0.0164
Trypanosoma brucei DNA polymerase kappa, putative 0.0006 0.0003 0.0156
Loa Loa (eye worm) hypothetical protein 0.0034 0.0069 0.0465
Schistosoma mansoni phd/f-box containing protein 0.0019 0.0035 0.007
Trichomonas vaginalis glutamate synthase, putative 0.0006 0.0003 0.0017
Echinococcus granulosus bloom syndrome protein 0.0008 0.0009 0.0019
Schistosoma mansoni carbonic anhydrase 0.0015 0.0025 0.005
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.0006 0.0032
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.0006 0.0032
Toxoplasma gondii PHD-finger domain-containing protein 0.006 0.0128 0.6152
Schistosoma mansoni opsin-like receptor 0.0034 0.0069 0.0139
Onchocerca volvulus 0.0006 0.0004 0.0011
Trypanosoma brucei DNA polymerase kappa, putative 0.0006 0.0003 0.0156
Onchocerca volvulus Huntingtin homolog 0.0125 0.0276 0.1613
Brugia malayi phosphofructokinase 0.0011 0.0016 0.0111
Echinococcus multilocularis dnaJ subfamily B 0.0429 0.097 0.1953
Echinococcus granulosus Solute carrier organic anion transporter family 0.0013 0.0019 0.0039
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0034 0.0069 0.0139
Brugia malayi P38 map kinase family protein 2 0.0037 0.0074 0.05
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0015 0.0025 0.005
Loa Loa (eye worm) jmjC domain-containing protein 0.0124 0.0274 0.184
Brugia malayi regulator of G-protein signaling egl-10 0.0005 0.0002 0.0013
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0034 0.0069 0.0139
Brugia malayi jmjC domain containing protein 0.0019 0.0035 0.0234
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0034 0.0069 0.0139
Echinococcus multilocularis neuropeptide FF receptor 2 0.0034 0.0069 0.0139
Schistosoma mansoni aldehyde dehydrogenase 0.0064 0.0137 0.0275
Onchocerca volvulus 0.0034 0.0069 0.0395
Trypanosoma cruzi ABC transporter, putative 0.001 0.0013 0.0751
Echinococcus multilocularis tumor susceptibility gene 101 protein 0.0073 0.0157 0.0316
Echinococcus multilocularis rhodopsin orphan GPCR 0.0034 0.0069 0.0139
Echinococcus granulosus TGF beta signal transducer SmadC 0.0009 0.001 0.0021
Loa Loa (eye worm) agrin synaptic family protein 0.0009 0.001 0.0069
Loa Loa (eye worm) hypothetical protein 0.0009 0.001 0.0069
Onchocerca volvulus 0.0006 0.0004 0.0011
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0006 0.0003 0.0121
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0021 0.0039 0.2244
Loa Loa (eye worm) hypothetical protein 0.0034 0.0069 0.0465
Loa Loa (eye worm) hypothetical protein 0.0006 0.0004 0.0029
Echinococcus multilocularis rhodopsin orphan GPCR 0.0034 0.0069 0.0139
Plasmodium vivax topoisomerase I, putative 0.0078 0.0169 0.817
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0012 0.0018 0.1054
Loa Loa (eye worm) intermediate filament protein 0.0014 0.0022 0.015
Onchocerca volvulus 0.0034 0.0069 0.0395
Loa Loa (eye worm) jmjC domain-containing protein 0.0019 0.0035 0.0233
Trichomonas vaginalis alpha-glucosidase, putative 0.0015 0.0024 0.0141
Echinococcus granulosus ecdysone induced protein 78C 0.0007 0.0006 0.0012
Echinococcus granulosus multidrug resistance protein 1 0.0011 0.0015 0.003
Mycobacterium ulcerans monoxygenase 0.0006 0.0003 0.0001
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0006 0.0003 0.0007
Brugia malayi hypothetical protein 0.0006 0.0004 0.003
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0015 0.0025 0.0168
Trichomonas vaginalis sucrase-isomaltase, putative 0.004 0.0082 0.0478
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0011 0.0016 0.0942
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0006 0.0032
Mycobacterium ulcerans isocitrate lyase Icl 0.4383 1 1
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0006 0.0003 0.0007
Loa Loa (eye worm) neuropeptide F receptor 0.0034 0.0069 0.0465
Onchocerca volvulus 0.0034 0.0069 0.0395
Loa Loa (eye worm) hypothetical protein 0.0006 0.0004 0.0029
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0006 0.0003 0.0017
Loa Loa (eye worm) hypothetical protein 0.0034 0.0069 0.0465
Echinococcus granulosus sex peptide receptor 0.0034 0.0069 0.0139

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) > 500 ug ml-1 Inhibition of Bacillus subtilis histidine kinase YycG ChEMBL. 17157007
IC50 (binding) > 500 ug ml-1 Inhibition of Bacillus subtilis histidine kinase YycG ChEMBL. 17157007
MIC (functional) > 100 ug ml-1 Antibacterial activity against methicillin-resistant staphylococcus aureus 870307 after 18 hrs by broth microdilution method ChEMBL. 17157007
MIC (functional) > 100 ug ml-1 Antibacterial activity against vancomycin-resistant Enterococcus faecalis NCTC12201 after 18 hrs by broth microdilution method ChEMBL. 17157007

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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