Detailed information for compound 562177

Basic information

Technical information
  • TDR Targets ID: 562177
  • Name: potassium (9E,12E,15E)-octadeca-9,12,15-trien oate
  • MW: 317.528 | Formula: C18H30KO2
  • H donors: 0 H acceptors: 2 LogP: 6.54 Rotable bonds: 13
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC/C=C/CC=CCC=CCCCCCCCC(=O)[O-].[KH+]
  • InChi: 1S/C18H30O2.K/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20;/h3-4,6-7,9-10H,2,5,8,11-17H2,1H3,(H,19,20);/q;+1/p-1/b4-3+,7-6+,10-9+;
  • InChiKey: FKEDIMSDTKPZNV-ICUOVBAUSA-M  


Substructure search Similarity search

Network

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Synonyms

  • 38660-45-6
  • EINECS 254-068-3
  • Potassium (9Z,12Z,15Z)-9,12,15-octadecatrienoate

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0008 0.0875
Brugia malayi cytoplasmic intermediate filament protein 0.003 0.0018 0.0018
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0013 0.0916
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.004 0.0028 0.0996
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0098 0.0083 0.0083
Mycobacterium tuberculosis Conserved protein 0.0037 0.0025 0.1122
Echinococcus granulosus neuropeptide receptor A26 0.0971 0.0923 0.0923
Loa Loa (eye worm) oxidoreductase 0.0012 0.0001 0.0001
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0004 0.0004
Schistosoma mansoni smad1 5 8 and 0.0017 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0037 0.0025 0.0025
Onchocerca volvulus 0.0048 0.0036 0.1483
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.0025 0.0025
Echinococcus multilocularis jumonji domain containing 1A 0.0041 0.0029 0.0029
Schistosoma mansoni short chain dehydrogenase 0.0012 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0029 0.0017 0.0017
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0021 0.001 0.0383
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0008 0.0875
Brugia malayi Bloom's syndrome protein homolog 0.0024 0.0012 0.0012
Trypanosoma cruzi polo-like protein kinase, putative 0.0094 0.008 1
Loa Loa (eye worm) lipocalin/cytosolic fatty-acid binding protein family protein 0.0042 0.0029 0.0029
Echinococcus multilocularis estradiol 17 beta dehydrogenase 12 0.0012 0.0001 0.0001
Loa Loa (eye worm) dehydrogenase 0.0012 0.0001 0.0001
Trypanosoma brucei metacaspase 0.0044 0.0032 0.3916
Echinococcus granulosus carbonyl reductase 1 0.0012 0.0001 0.0001
Echinococcus multilocularis geminin 0.0361 0.0336 0.0336
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.0004 0.027
Brugia malayi Smad1 0.0017 0.0006 0.0006
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0021 0.001 0.001
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0016 0.0004 0.0004
Echinococcus multilocularis musashi 0.0057 0.0044 0.0044
Echinococcus granulosus fatty acid binding protein FABP2 0.0123 0.0107 0.0107
Echinococcus granulosus lamin 0.0057 0.0044 0.0044
Loa Loa (eye worm) hypothetical protein 0.0021 0.001 0.001
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0016 0.0004 0.0484
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0098 0.0083 0.0083
Schistosoma mansoni hypothetical protein 0.0083 0.0069 0.0069
Onchocerca volvulus Serine\/threonine kinase homolog 0.0094 0.008 0.3343
Loa Loa (eye worm) oxidoreductase 0.0012 0.0001 0.0001
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0037 0.0025 0.1122
Trypanosoma cruzi metacaspase, putative 0.0044 0.0032 0.3916
Echinococcus multilocularis steroid dehydrogenase 0.0012 0.0001 0.0001
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0037 0.0025 0.1723
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0041 0.0029 0.3583
Loa Loa (eye worm) hypothetical protein 0.0257 0.0237 0.0236
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0037 0.0025 0.1122
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0041 0.0029 0.2002
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0008 0.0875
Echinococcus multilocularis isocitrate dehydrogenase 0.0016 0.0004 0.0004
Echinococcus granulosus WW domain containing oxidoreductase 0.0012 0.0001 0.0001
Plasmodium falciparum steroid dehydrogenase, putative 0.0012 0.0001 0.0034
Schistosoma mansoni short-chain dehydrogenase/reductase 0.0012 0.0001 0.0001
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0159 0.0142 1
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0032 0.1146
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0021 0.001 0.001
Trichomonas vaginalis CAMK family protein kinase 0.0094 0.008 0.2925
Schistosoma mansoni steroid dehydrogenase 0.0012 0.0001 0.0001
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0044 0.0032 0.0032
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0044 0.0032 0.2189
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0292 0.027 1
Brugia malayi PHD-finger family protein 0.0011 0.0000081896 0.00000076486
Loa Loa (eye worm) oxidoreductase 0.0012 0.0001 0.0001
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0163 0.0146 0.5405
Loa Loa (eye worm) RecQ helicase 0.0024 0.0012 0.0012
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0098 0.0083 0.0083
Echinococcus multilocularis mothers against decapentaplegic 5 0.0017 0.0006 0.0006
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0013 0.0916
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0237 0.0217 1
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0021 0.001 0.001
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0041 0.0029 0.3583
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0094 0.008 0.008
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0008 0.0875
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0032 0.1146
Trypanosoma brucei polo-like protein kinase 0.0094 0.008 1
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0208 0.0189 0.0189
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0012 0.0001 0.0034
Loa Loa (eye worm) hypothetical protein 0.0021 0.001 0.001
Plasmodium vivax SET domain protein, putative 0.003 0.0018 0.1288
Loa Loa (eye worm) hypothetical protein 0.0159 0.0142 0.0142
Mycobacterium leprae conserved hypothetical protein 0.0037 0.0025 0.1723
Echinococcus multilocularis transient receptor potential cation channel 0.0012 0.0001 0.0001
Toxoplasma gondii histone lysine methyltransferase SET1 0.0057 0.0044 0.3097
Trypanosoma brucei metacaspase MCA2 0.0044 0.0032 0.3916
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0013 0.0002 0.0089
Leishmania major DNA polymerase eta, putative 0.0044 0.0032 0.2898
Schistosoma mansoni steroid dehydrogenase 0.0012 0.0001 0.0001
Brugia malayi isocitrate dehydrogenase 0.0016 0.0004 0.0004
Trichomonas vaginalis CAMK family protein kinase 0.0094 0.008 0.2925
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0013 0.1584
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0159 0.0142 1
Schistosoma mansoni short chain dehydrogenase 0.0012 0.0001 0.0001
Schistosoma mansoni short chain dehydrogenase 0.0012 0.0001 0.0001
Trypanosoma brucei DNA polymerase eta, putative 0.0044 0.0032 0.3933
Loa Loa (eye worm) hypothetical protein 0.0021 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0011 0.0000081896 0.00000076486
Echinococcus multilocularis carbonyl reductase 1 0.0012 0.0001 0.0001
Echinococcus multilocularis caspase 0.0116 0.0101 0.0101
Loa Loa (eye worm) hypothetical protein 0.003 0.0018 0.0018
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0263 0.0242 0.0242
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0215 0.0196 0.0196
Onchocerca volvulus 0.0104 0.0089 0.3741
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0123 0.0108 0.494
Echinococcus multilocularis Smad4 0.0017 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0257 0.0237 0.0236
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.012 0.0105 0.4816
Trichomonas vaginalis CAMK family protein kinase 0.0046 0.0034 0.1235
Schistosoma mansoni short chain dehydrogenase 0.0012 0.0001 0.0001
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0031 0.0019 0.1305
Brugia malayi Pre-SET motif family protein 0.003 0.0018 0.0018
Schistosoma mansoni jumonji/arid domain-containing protein 0.0156 0.0139 0.0139
Onchocerca volvulus 0.0041 0.0029 0.1186
Loa Loa (eye worm) steroid hormone receptor 0.0021 0.001 0.001
Echinococcus granulosus jumonji domain containing 1A 0.0041 0.0029 0.0029
Trypanosoma cruzi metacaspase, putative 0.0044 0.0032 0.3916
Echinococcus multilocularis JmjC domain containing protein 4 0.0041 0.0029 0.0029
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0044 0.0032 0.1146
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0019 0.0008 0.0008
Echinococcus multilocularis neutral alpha glucosidase AB 0.004 0.0028 0.0028
Loa Loa (eye worm) hypothetical protein 0.0021 0.001 0.001
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0215 0.0196 0.0196
Onchocerca volvulus Bile acid receptor homolog 0.0021 0.001 0.0383
Loa Loa (eye worm) hypothetical protein 0.0012 0.0001 0.0001
Brugia malayi beta-lactamase 0.0037 0.0025 0.0025
Echinococcus granulosus oxidoreductase 0.0012 0.0001 0.0001
Schistosoma mansoni smad1 5 8 and 0.0017 0.0006 0.0006
Echinococcus granulosus apoptotic protease activating factor 1 0.0041 0.0029 0.0029
Plasmodium vivax metacaspase 1, putative 0.0044 0.0032 0.2215
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0029 0.0017 0.0017
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.004 0.0028 0.0996
Echinococcus multilocularis caspase 2 0.0085 0.0071 0.0071
Schistosoma mansoni lamin 0.0057 0.0044 0.0044
Echinococcus granulosus peregrin 0.0029 0.0017 0.0017
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0001 0.0001
Brugia malayi ImpB/MucB/SamB family protein 0.0044 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0021 0.001 0.001
Schistosoma mansoni transcription factor LCR-F1 0.0075 0.0061 0.0061
Echinococcus multilocularis peregrin 0.0029 0.0017 0.0017
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0016 0.0005 0.0332
Echinococcus multilocularis beta LACTamase domain containing family member 0.0037 0.0025 0.0025
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0044 0.0032 0.1146
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0013 0.1584
Brugia malayi CXXC zinc finger family protein 0.003 0.0018 0.0018
Brugia malayi nuclear receptor NHR-88 0.0021 0.001 0.001
Echinococcus multilocularis PHD finger protein rhinoceros 0.0029 0.0017 0.0017
Treponema pallidum fructose-bisphosphate aldolase 0.0292 0.027 1
Schistosoma mansoni short chain dehydrogenase 0.0012 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0021 0.001 0.001
Schistosoma mansoni caspase-7 (C14 family) 0.0085 0.0071 0.0071
Brugia malayi hypothetical protein 0.0012 0.0001 0.0001
Onchocerca volvulus Cell death protein 3 homolog 0.0085 0.0071 0.2977
Loa Loa (eye worm) oxidoreductase 0.0012 0.0001 0.0001
Entamoeba histolytica hypothetical protein 0.0075 0.0061 0.2253
Brugia malayi MH1 domain containing protein 0.0017 0.0006 0.0006
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.0028 0.3405
Brugia malayi MH1 domain containing protein 0.0017 0.0006 0.0006
Schistosoma mansoni hypothetical protein 0.0083 0.0069 0.0069
Trichomonas vaginalis maltase-glucoamylase, putative 0.004 0.0028 0.0996
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0008 0.0875
Loa Loa (eye worm) CXXC zinc finger family protein 0.003 0.0018 0.0018
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.012 0.0105 0.0105
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0032 0.1146
Trichomonas vaginalis alpha-glucosidase, putative 0.004 0.0028 0.0996
Plasmodium falciparum phd finger protein, putative 0.0029 0.0017 0.121
Schistosoma mansoni lamin 0.0057 0.0044 0.0044
Loa Loa (eye worm) hypothetical protein 0.0044 0.0032 0.0031
Brugia malayi hypothetical protein 0.0041 0.0029 0.0029
Echinococcus granulosus smad 0.0017 0.0006 0.0006
Echinococcus multilocularis carbonyl reductase 1 0.0012 0.0001 0.0001
Trypanosoma cruzi DNA polymerase eta, putative 0.0031 0.0019 0.2335
Trypanosoma brucei DNA polymerase kappa, putative 0.0013 0.0002 0.0156
Leishmania major DNA polymerase eta, putative 0.0031 0.0019 0.1721
Brugia malayi jmjC domain containing protein 0.0041 0.0029 0.0029
Schistosoma mansoni cpg binding protein 0.0031 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.0012 0.0001 0.0001
Trypanosoma brucei DNA polymerase kappa, putative 0.0013 0.0002 0.0156
Schistosoma mansoni short chain dehydrogenase 0.0012 0.0001 0.0001
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0025 0.0902
Loa Loa (eye worm) hypothetical protein 0.0012 0.0001 0.0001
Trichomonas vaginalis DNA helicase recq, putative 0.0013 0.0002 0.0035
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.0017 0.0017
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0123 0.0108 1
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0064 0.0051 0.0051
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0123 0.0108 0.0108
Echinococcus granulosus histone lysine methyltransferase setb 0.003 0.0018 0.0018
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0109 0.0094 0.0094
Schistosoma mansoni steroid dehydrogenase 0.0012 0.0001 0.0001
Schistosoma mansoni short chain dehydrogenase 0.0012 0.0001 0.0001
Loa Loa (eye worm) PHD-finger family protein 0.0029 0.0017 0.0017
Trichomonas vaginalis alpha-glucosidase, putative 0.004 0.0028 0.0996
Loa Loa (eye worm) short chain dehydrogenase/reductase family oxidoreductase 0.0012 0.0001 0.0001
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0015 0.0004 0.0106
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0083 0.0069 0.0069
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0016 0.0005 0.0287
Brugia malayi hypothetical protein 0.0025 0.0013 0.0013
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0008 0.0875
Loa Loa (eye worm) hypothetical protein 0.0041 0.0029 0.0029
Brugia malayi serine/threonine-protein kinase plk-2 0.0094 0.008 0.0079
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0292 0.027 1
Schistosoma mansoni steroid dehydrogenase 0.0012 0.0001 0.0001
Brugia malayi hypothetical protein 0.0237 0.0217 0.0216
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.0004 0.027
Toxoplasma gondii hypothetical protein 0.0055 0.0042 0.2917
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0094 0.008 0.7368
Schistosoma mansoni terminal deoxycytidyl transferase 0.0019 0.0008 0.0008
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0104 0.0089 0.4089
Echinococcus granulosus caspase 0.0116 0.0101 0.0101
Brugia malayi hypothetical protein 0.0075 0.0061 0.0061
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.003 0.0018 0.0018
Brugia malayi Glycosyl hydrolases family 31 protein 0.0015 0.0004 0.0003
Loa Loa (eye worm) hypothetical protein 0.0012 0.0001 0.0001
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0057 0.0044 0.0044
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0004 0.0356
Echinococcus multilocularis dna polymerase kappa 0.0019 0.0008 0.0008
Brugia malayi dehydrogenases, short chain protein 2 0.0012 0.0001 0.0001
Mycobacterium ulcerans aldehyde dehydrogenase 0.0123 0.0108 0.7584
Plasmodium vivax hypothetical protein, conserved 0.0044 0.0032 0.2215
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0104 0.0089 0.4089
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0021 0.001 0.0662
Schistosoma mansoni DNA polymerase eta 0.0044 0.0032 0.0032
Leishmania major metacaspase, putative 0.0044 0.0032 0.2886
Echinococcus multilocularis retinol dehydrogenase 11 0.0012 0.0001 0.0001
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0098 0.0083 0.0083
Echinococcus granulosus FTZ F1 alpha 0.0021 0.001 0.001
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0001 0.0001
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0016 0.0004 0.0303
Onchocerca volvulus 0.0057 0.0044 0.1825
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0004 0.0484
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0021 0.001 0.001
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0021 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0037 0.0025 0.0025
Trypanosoma brucei unspecified product 0.0013 0.0002 0.0156
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0013 0.0002 0.0121
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0041 0.0029 0.0029
Echinococcus multilocularis caspase 3 0.0072 0.0059 0.0059
Schistosoma mansoni fatty acid binding protein 0.0123 0.0107 0.0107
Loa Loa (eye worm) jmjC domain-containing protein 0.0041 0.0029 0.0029
Echinococcus multilocularis retinol dehydrogenase 13 0.0012 0.0001 0.0001
Loa Loa (eye worm) transcription factor SMAD2 0.0251 0.023 0.023
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0019 0.0008 0.0008
Schistosoma mansoni jumonji/arid domain-containing protein 0.0156 0.0139 0.0139
Echinococcus multilocularis carbonyl reductase 1 0.0012 0.0001 0.0001
Trypanosoma brucei glucosidase, putative 0.004 0.0028 0.3405
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0013 0.0916
Echinococcus granulosus caspase 8 0.0044 0.0032 0.0032
Schistosoma mansoni retinal dehydrogenase 0.0012 0.0001 0.0001
Plasmodium vivax JmjC domain containing protein 0.0041 0.0029 0.2029
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0098 0.0083 0.0083
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0021 0.001 0.001
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.001 0.001
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0008 0.0875
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0083 0.0069 0.0069
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0001 0.0001
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0004 0.0484
Onchocerca volvulus 0.003 0.0018 0.0753
Brugia malayi hypothetical protein 0.0012 0.0001 0.0001
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0011 0.0000074247 0.0000074247
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0021 0.001 0.001
Trypanosoma brucei metacaspase 5, putative 0.0044 0.0032 0.3916
Loa Loa (eye worm) hypothetical protein 0.0021 0.001 0.001
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0021 0.001 0.001
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0021 0.001 0.001
Trypanosoma cruzi polo-like protein kinase, putative 0.0094 0.008 1
Schistosoma mansoni peptidase Clp (S14 family) 0.0159 0.0142 0.0142
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0044 0.0032 0.1146
Echinococcus granulosus hypothetical protein 0.0012 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0044 0.0032 0.0032
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0016 0.0004 0.0004
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0057 0.0044 0.0044
Trichomonas vaginalis alpha-glucosidase, putative 0.004 0.0028 0.0996
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0044 0.0032 0.1146
Loa Loa (eye worm) dehydrogenase 0.0012 0.0001 0.0001
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0143 0.0127 0.8919
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0292 0.027 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0021 0.001 0.001
Echinococcus multilocularis GPCR, family 2 0.0083 0.0069 0.0069
Leishmania major hypothetical protein, conserved 0.0037 0.0025 0.2272
Entamoeba histolytica hypothetical protein 0.0075 0.0061 0.2253
Leishmania major hypothetical protein, conserved 0.0025 0.0013 0.1167
Loa Loa (eye worm) hypothetical protein 0.0083 0.0069 0.0069
Schistosoma mansoni aldehyde dehydrogenase 0.0123 0.0108 0.0108
Echinococcus multilocularis lamin dm0 0.0057 0.0044 0.0044
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.001 0.001
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0013 0.1584
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0008 0.0875
Echinococcus multilocularis carbonyl reductase 1 0.0012 0.0001 0.0001
Schistosoma mansoni short chain dehydrogenase 0.0012 0.0001 0.0001
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0025 0.0902
Echinococcus granulosus cpg binding protein 0.0031 0.0019 0.0019
Echinococcus multilocularis epidermal retinal dehydrogenase 2 0.0012 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0082 0.0068 0.0068
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0075 0.0061 0.0061
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0016 0.0004 0.0176
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.004 0.0028 0.0027
Echinococcus granulosus epidermal retinal dehydrogenase 2 0.0012 0.0001 0.0001
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0021 0.001 0.001
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0292 0.027 1
Schistosoma mansoni RAR-like nuclear receptor 0.0021 0.001 0.001
Onchocerca volvulus 0.0037 0.0025 0.1031
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.0025 0.0025
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0018 0.0018
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0159 0.0142 0.0142
Echinococcus granulosus lysine specific demethylase 6a 0.0041 0.0029 0.0029
Brugia malayi Steroid receptor seven-up type 2 0.0021 0.001 0.001
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0015 0.0004 0.0106
Echinococcus granulosus retinol dehydrogenase 11 0.0012 0.0001 0.0001
Echinococcus granulosus carbonyl reductase 1 0.0012 0.0001 0.0001
Entamoeba histolytica hypothetical protein 0.0075 0.0061 0.2253
Echinococcus granulosus lamin dm0 0.0057 0.0044 0.0044
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0143 0.0127 0.8919
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0044 0.0032 0.1146
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0019 0.0008 0.0007
Schistosoma mansoni blooms syndrome DNA helicase 0.0019 0.0008 0.0008
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0018 0.0018
Trypanosoma brucei hypothetical protein, conserved 0.0037 0.0025 0.3084
Schistosoma mansoni short chain dehydrogenase 0.0012 0.0001 0.0001
Echinococcus multilocularis microtubule associated protein 2 0.1445 0.1378 0.1378
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0019 0.0008 0.0008
Brugia malayi Glycosyl hydrolases family 31 protein 0.004 0.0028 0.0027
Schistosoma mansoni phd/f-box containing protein 0.0041 0.0029 0.0029
Schistosoma mansoni hypothetical protein 0.0083 0.0069 0.0069
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0015 0.0004 0.0121
Trichomonas vaginalis alpha-glucosidase, putative 0.0015 0.0004 0.0106
Echinococcus granulosus retinol dehydrogenase 11 0.0012 0.0001 0.0001
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0008 0.0875
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0037 0.0025 0.1122
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0011 0.0000074247 0.0000074247
Plasmodium vivax steroid dehydrogenase, putative 0.0012 0.0001 0.0034
Loa Loa (eye worm) hypothetical protein 0.018 0.0162 0.0162
Brugia malayi Pre-SET motif family protein 0.0208 0.0189 0.0189
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0075 0.0061 0.0061
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.012 0.0105 0.7393
Schistosoma mansoni steroid dehydrogenase 0.0012 0.0001 0.0001
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0015 0.0004 0.0106
Loa Loa (eye worm) oxidoreductase 0.0012 0.0001 0.0001
Mycobacterium ulcerans aldehyde dehydrogenase 0.0123 0.0108 0.7584
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0041 0.0029 0.2002
Schistosoma mansoni steroid hormone receptor ad4bp 0.0021 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0015 0.0004 0.0003
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0098 0.0083 0.0083
Loa Loa (eye worm) hypothetical protein 0.0027 0.0016 0.0015
Brugia malayi F/Y-rich N-terminus family protein 0.002 0.0008 0.0008
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0098 0.0083 0.0083
Schistosoma mansoni oxidoreductase short chain dehydrogenase/reductase family 0.0012 0.0001 0.0001
Echinococcus granulosus 3 ketodihydrosphingosine reductase 0.0012 0.0001 0.0001
Brugia malayi MH2 domain containing protein 0.0017 0.0006 0.0006
Plasmodium vivax hypothetical protein, conserved 0.0012 0.0001 0.0034
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0021 0.001 0.001
Schistosoma mansoni steroid dehydrogenase 0.0012 0.0001 0.0001
Brugia malayi Cell death protein 3 precursor 0.0085 0.0071 0.0071
Echinococcus multilocularis lysosomal alpha glucosidase 0.0179 0.0162 0.0162
Brugia malayi ecdysteroid receptor 0.0021 0.001 0.001
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0021 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0021 0.001 0.001
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0008 0.0875
Entamoeba histolytica deoxycytidyl transferase, putative 0.0019 0.0008 0.0256
Brugia malayi Bromodomain containing protein 0.0029 0.0017 0.0017
Echinococcus multilocularis fatty acid binding protein FABP2 0.0123 0.0107 0.0107
Trichomonas vaginalis DNA polymerase eta, putative 0.0019 0.0008 0.0256
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0004 0.0004
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0018 0.0018
Schistosoma mansoni alpha-glucosidase 0.0154 0.0138 0.0138
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0055 0.0042 0.2941
Plasmodium vivax hypothetical protein, conserved 0.0037 0.0025 0.1751
Leishmania major alpha glucosidase II subunit, putative 0.004 0.0028 0.2509
Trichomonas vaginalis CAMK family protein kinase 0.0046 0.0034 0.1235
Brugia malayi jmjC domain containing protein 0.0041 0.0029 0.0029
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0044 0.0032 0.2189
Brugia malayi hypothetical protein 0.0257 0.0237 0.0236
Echinococcus multilocularis phd:f box containing protein 0.0041 0.0029 0.0029
Onchocerca volvulus 0.0236 0.0216 0.9135
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0179 0.0162 0.0161
Trichomonas vaginalis alpha-glucosidase, putative 0.0015 0.0004 0.0106
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0043 0.0031 0.0031
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0001 0.0001
Echinococcus multilocularis lamin 0.0057 0.0044 0.0044
Loa Loa (eye worm) hypothetical protein 1.042 1 1
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0263 0.0242 0.0242
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0004 0.0004
Onchocerca volvulus Protein ultraspiracle homolog 0.0021 0.001 0.0383
Brugia malayi D-beta-hydroxybutyrate dehydrogenase, mitochondrial precursor 0.0012 0.0001 0.0001
Trichomonas vaginalis CAMK family protein kinase 0.0094 0.008 0.2925
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0021 0.001 0.001
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0001 0.0001
Echinococcus multilocularis neuropeptide receptor A26 0.0971 0.0923 0.0923
Trichomonas vaginalis alpha-glucosidase, putative 0.004 0.0028 0.0996
Plasmodium vivax hypothetical protein, conserved 0.0029 0.0017 0.121
Loa Loa (eye worm) hypothetical protein 0.0163 0.0146 0.0146
Echinococcus granulosus fatty acid binding protein FABP2 0.0123 0.0107 0.0107
Onchocerca volvulus 0.0057 0.0044 0.1825
Schistosoma mansoni short chain dehydrogenase 0.0012 0.0001 0.0001
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.001 0.001
Mycobacterium ulcerans beta-lactamase 0.0037 0.0025 0.1723
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0021 0.001 0.001
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.003 0.0018 0.0018
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0021 0.001 0.001
Brugia malayi photoreceptor-specific nuclear receptor 0.0021 0.001 0.001
Trichomonas vaginalis sucrase-isomaltase, putative 0.004 0.0028 0.0996
Schistosoma mansoni short chain dehydrogenase 0.0012 0.0001 0.0001
Echinococcus granulosus peptidase Clp S14 family 0.0104 0.0089 0.0089
Schistosoma mansoni microtubule-associated protein tau 0.1445 0.1378 0.1378
Echinococcus multilocularis smad 0.0017 0.0006 0.0006
Trichomonas vaginalis DNA helicase recq1, putative 0.0024 0.0012 0.0434
Echinococcus multilocularis alpha 1,6 mannosyl glycoprotein 1.042 1 1
Schistosoma mansoni kinase 0.0048 0.0035 0.0035
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.001 0.001
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0027 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0263 0.0242 0.0242
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0001 0.0001
Echinococcus multilocularis FTZ F1 alpha 0.0021 0.001 0.001
Brugia malayi oxidoreductase 0.0012 0.0001 0.0001
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0017 0.118
Schistosoma mansoni steroid dehydrogenase 0.0012 0.0001 0.0001
Schistosoma mansoni hypothetical protein 0.018 0.0162 0.0162
Loa Loa (eye worm) beta-lactamase 0.0037 0.0025 0.0025
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.012 0.0105 0.0105
Echinococcus granulosus neutral alpha glucosidase AB 0.004 0.0028 0.0028
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0016 0.0004 0.0484
Brugia malayi Dehydrogenases, short chain protein 2 0.0012 0.0001 0.0001
Giardia lamblia PHD finger protein 15 0.0029 0.0017 0.0618
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0015 0.0004 0.0363
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0025 0.3084
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0037 0.0025 0.0025
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0021 0.001 0.001
Brugia malayi latrophilin 2 splice variant baaae 0.018 0.0162 0.0162
Schistosoma mansoni fatty acid binding protein 0.0123 0.0107 0.0107
Echinococcus granulosus jumonji domain containing protein 0.0041 0.0028 0.0028
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0163 0.0146 0.5405
Trichomonas vaginalis DNA helicase recq, putative 0.0024 0.0012 0.0434
Echinococcus multilocularis jumonji domain containing protein 0.0041 0.0028 0.0028
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0292 0.027 1
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0123 0.0108 0.0108
Loa Loa (eye worm) MH1 domain-containing protein 0.0017 0.0006 0.0006
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0001 0.0001
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0292 0.027 1
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0083 0.0069 0.0069
Trichomonas vaginalis penicillin-binding protein, putative 0.0037 0.0025 0.0902
Loa Loa (eye worm) isocitrate dehydrogenase 0.0016 0.0004 0.0004
Mycobacterium tuberculosis Conserved protein 0.0037 0.0025 0.1122
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0013 0.0885
Brugia malayi steroid hormone receptor 0.0021 0.001 0.001
Leishmania major hypothetical protein, conserved 0.0041 0.0029 0.264
Schistosoma mansoni Smad4 0.0017 0.0006 0.0006
Echinococcus multilocularis 3 ketodihydrosphingosine reductase 0.0012 0.0001 0.0001
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0001 0.0001
Echinococcus granulosus intermediate filament protein 0.0057 0.0044 0.0044
Schistosoma mansoni thyroid hormone receptor 0.0021 0.001 0.001
Schistosoma mansoni nuclear hormone receptor 0.0021 0.001 0.001
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0011 0.0000074247 0.0000074247
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0019 0.0008 0.0318
Schistosoma mansoni hypothetical protein 0.0361 0.0336 0.0336
Schistosoma mansoni carbonyl reductase 0.0012 0.0001 0.0001
Loa Loa (eye worm) oxidoreductase 0.0012 0.0001 0.0001
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0159 0.0142 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0292 0.027 1
Loa Loa (eye worm) jmjC domain-containing protein 0.0041 0.0029 0.0029
Trypanosoma brucei glycosyl hydrolase-like protein 0.0015 0.0004 0.0363
Loa Loa (eye worm) hypothetical protein 0.0041 0.0029 0.0029
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0008 0.0007
Schistosoma mansoni serine/threonine protein kinase 0.0094 0.008 0.008
Entamoeba histolytica recQ family helicase, putative 0.0013 0.0002 0.0035
Trichomonas vaginalis alpha-glucosidase, putative 0.0015 0.0004 0.0106
Schistosoma mansoni cpg binding protein 0.003 0.0018 0.0018
Schistosoma mansoni thyroid hormone receptor 0.0021 0.001 0.001
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0044 0.0032 0.1146
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0017 0.0006 0.0006
Giardia lamblia Fructose-bisphosphate aldolase 0.0292 0.027 1
Brugia malayi jmjC domain containing protein 0.0215 0.0196 0.0196
Brugia malayi Retinol dehydrogenase 12 0.0012 0.0001 0.0001
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0025 0.3084
Trypanosoma brucei DNA polymerase kappa, putative 0.0013 0.0002 0.0156
Loa Loa (eye worm) hypothetical protein 0.0012 0.0001 0.0001
Schistosoma mansoni steroid dehydrogenase 0.0012 0.0001 0.0001
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.001 0.001
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0027 0.0016 0.0016
Echinococcus granulosus TGF beta signal transducer SmadC 0.0017 0.0006 0.0006
Schistosoma mansoni alpha glucosidase 0.004 0.0028 0.0028
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.001 0.001
Loa Loa (eye worm) jmjC domain-containing protein 0.006 0.0047 0.0047
Schistosoma mansoni survival motor neuron protein 0.0048 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0012 0.0001 0.0001
Giardia lamblia Kinase, PLK 0.0094 0.008 0.2925
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0016 0.0004 0.0303
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.001 0.001
Echinococcus granulosus PHD finger protein rhinoceros 0.0029 0.0017 0.0017
Loa Loa (eye worm) jmjC domain-containing protein 0.0156 0.0139 0.0139
Trichomonas vaginalis CAMK family protein kinase 0.0094 0.008 0.2925
Echinococcus granulosus beta LACTamase domain containing family member 0.0037 0.0025 0.0025
Loa Loa (eye worm) intermediate filament protein 0.0057 0.0044 0.0044
Loa Loa (eye worm) hypothetical protein 0.0037 0.0025 0.0025
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0159 0.0142 0.5
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0032 0.1146
Brugia malayi beta-lactamase family protein 0.0037 0.0025 0.0025
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0839 0.0796 0.0796
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0292 0.027 1
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0159 0.0142 1
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0159 0.0142 0.0142
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0041 0.0029 0.3583
Schistosoma mansoni caspase-7 (C14 family) 0.0116 0.0101 0.0101
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.0028 0.3405
Loa Loa (eye worm) hypothetical protein 0.0037 0.0025 0.0025
Echinococcus granulosus caspase 3 0.0072 0.0059 0.0059
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0159 0.0142 0.4376
Brugia malayi MH2 domain containing protein 0.0251 0.023 0.023
Brugia malayi dehydrogenases, short chain protein 9 0.0012 0.0001 0.0001
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0001 0.0001
Echinococcus granulosus lysine specific demethylase 5A 0.0156 0.0139 0.0139
Trichomonas vaginalis CAMK family protein kinase 0.0094 0.008 0.2925
Brugia malayi Dehydrogenases, short chain protein 30 0.0012 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0026 0.0015 0.0014
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0083 0.0069 0.0069
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0044 0.0032 0.1146
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.012 0.0105 0.9748
Plasmodium falciparum JmjC domain-containing protein, putative 0.0041 0.0029 0.2029
Trichomonas vaginalis CAMK family protein kinase 0.0094 0.008 0.2925
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0008 0.0875
Echinococcus multilocularis fatty acid binding protein FABP2 0.0081 0.0067 0.0067
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0001 0.0001
Echinococcus granulosus fatty acid binding protein, adipocyte 0.0081 0.0067 0.0067
Schistosoma mansoni jumonji domain containing protein 0.0041 0.0029 0.0029
Echinococcus multilocularis oxidoreductase 0.0012 0.0001 0.0001
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0044 0.0032 0.0031
Trypanosoma cruzi metacaspase 5, putative 0.0044 0.0032 0.3916
Schistosoma mansoni short chain dehydrogenase 0.0012 0.0001 0.0001
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.012 0.0105 0.0105
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.004 0.0028 0.0996
Brugia malayi jmjC domain containing protein 0.0041 0.0029 0.0029
Loa Loa (eye worm) oxidoreductase 0.0012 0.0001 0.0001
Trypanosoma brucei unspecified product 0.0013 0.0002 0.0156
Echinococcus granulosus Dehydrogenase:reductase SDR family 0.0012 0.0001 0.0001
Echinococcus multilocularis peptidase Clp (S14 family) 0.0104 0.0089 0.0089
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0008 0.0875
Trypanosoma cruzi DNA polymerase eta, putative 0.0044 0.0032 0.3933
Leishmania major glycosyl hydrolase-like protein 0.0015 0.0004 0.0268
Echinococcus granulosus mothers against decapentaplegic 5 0.0017 0.0006 0.0006
Toxoplasma gondii aldehyde dehydrogenase 0.0123 0.0108 0.7584
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0001 0.0001
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0159 0.0142 1
Brugia malayi Latrophilin receptor protein 2 0.0083 0.0069 0.0069
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0001 0.0001
Echinococcus granulosus Smad4 0.0017 0.0006 0.0006
Onchocerca volvulus 0.0037 0.0025 0.1031
Loa Loa (eye worm) hypothetical protein 0.0025 0.0013 0.0013
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.003 0.0018 0.0018
Schistosoma mansoni steroid dehydrogenase 0.0012 0.0001 0.0001
Echinococcus granulosus dna polymerase eta 0.0044 0.0032 0.0032
Plasmodium falciparum oxidoreductase, short-chain dehydrogenase family, putative 0.0012 0.0001 0.0034
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0021 0.001 0.001
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0021 0.001 0.001
Schistosoma mansoni 3-keto-dihydrosphingosine reductase 0.0012 0.0001 0.0001
Echinococcus granulosus microtubule associated protein 2 0.1445 0.1378 0.1378
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0159 0.0142 1
Loa Loa (eye worm) hypothetical protein 0.0026 0.0015 0.0014
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0032 0.1146
Loa Loa (eye worm) hypothetical protein 0.0012 0.0001 0.0001
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0008 0.0875
Schistosoma mansoni steroid dehydrogenase 0.0012 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0012 0.0001 0.0001
Echinococcus multilocularis thyroid hormone receptor alpha 0.0021 0.001 0.001
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0098 0.0083 0.0083
Echinococcus multilocularis steroid dehydrogenase 0.0012 0.0001 0.0001
Schistosoma mansoni hypothetical protein 0.0423 0.0395 0.0395
Schistosoma mansoni retinoic acid receptor RXR 0.0021 0.001 0.001
Echinococcus granulosus dna polymerase kappa 0.0019 0.0008 0.0008
Echinococcus granulosus caspase 2 0.0085 0.0071 0.0071
Echinococcus granulosus bloom syndrome protein 0.0024 0.0012 0.0012
Loa Loa (eye worm) MH2 domain-containing protein 0.0017 0.0006 0.0006
Schistosoma mansoni jumonji domain containing protein 0.0195 0.0177 0.0177
Trichomonas vaginalis CAMK family protein kinase 0.0094 0.008 0.2925
Brugia malayi Glycosyl hydrolases family 31 protein 0.0179 0.0162 0.0161
Schistosoma mansoni hypothetical protein 0.0041 0.0029 0.0029
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0021 0.001 0.001
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0094 0.008 0.0079
Leishmania major DNA polymerase kappa, putative 0.0019 0.0008 0.0645
Echinococcus granulosus GPCR family 2 0.0083 0.0069 0.0069
Mycobacterium tuberculosis Probable lipase LipE 0.0037 0.0025 0.1122
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0021 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0037 0.0025 0.0025
Schistosoma mansoni short chain dehydrogenase 0.0012 0.0001 0.0001
Onchocerca volvulus 0.003 0.0018 0.0727
Schistosoma mansoni cpg binding protein 0.0031 0.0019 0.0019
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0001 0.0001
Schistosoma mansoni beta-12-n-acetylglucosaminyltransferase II 1.042 1 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0008 0.0875
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0021 0.001 0.001
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0159 0.0142 0.5
Schistosoma mansoni carbonyl reductase 0.0012 0.0001 0.0001
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0018 0.1259
Schistosoma mansoni hypothetical protein 0.0075 0.0061 0.0061
Echinococcus multilocularis survival motor neuron protein 1 0.0237 0.0217 0.0217
Mycobacterium leprae Probable lipase LipE 0.0037 0.0025 0.1723
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0008 0.0489
Trichomonas vaginalis maltase-glucoamylase, putative 0.0015 0.0004 0.0106
Trypanosoma brucei metacaspase MCA3 0.0044 0.0032 0.3916
Brugia malayi Lipocalin / cytosolic fatty-acid binding protein family protein 0.0042 0.0029 0.0029
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.012 0.0105 0.7393
Loa Loa (eye worm) Smad1 0.0017 0.0006 0.0006
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0292 0.027 1
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0021 0.001 0.001
Entamoeba histolytica serine/threonine protein kinase, putative 0.0094 0.008 0.2925
Mycobacterium tuberculosis Probable esterase LipL 0.0037 0.0025 0.1122
Trypanosoma brucei Metacaspase-4 0.0044 0.0032 0.3916
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0001 0.0001
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0037 0.0025 0.0025
Schistosoma mansoni protein phosphatase 2C 0.0041 0.0029 0.0029
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0021 0.001 0.001
Echinococcus granulosus carbonyl reductase 1 0.0012 0.0001 0.0001
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0104 0.0089 0.6277
Loa Loa (eye worm) hypothetical protein 0.0056 0.0043 0.0043
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0018 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0012 0.0001 0.0001
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0044 0.0032 0.2189
Plasmodium falciparum metacaspase 1 0.0044 0.0032 0.2215
Echinococcus granulosus ecdysone induced protein 78C 0.0021 0.001 0.001
Entamoeba histolytica hypothetical protein 0.0075 0.0061 0.2253
Echinococcus multilocularis neuropeptide s receptor 0.0971 0.0923 0.0923
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0055 0.0042 0.2941
Trypanosoma cruzi metacaspase, putative 0.0044 0.0032 0.3916
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0008 0.0875
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0001 0.0001
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0013 0.0002 0.0121
Echinococcus multilocularis retinol dehydrogenase 11 0.0012 0.0001 0.0001
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0292 0.027 1
Brugia malayi jmjC domain containing protein 0.0041 0.0029 0.0029
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0021 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0085 0.0071 0.0071
Plasmodium falciparum metacaspase-like protein 0.0044 0.0032 0.2215
Brugia malayi beta-lactamase family protein 0.0037 0.0025 0.0025
Brugia malayi nuclear hormone receptor 0.0021 0.001 0.001
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.012 0.0105 0.0105
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.001 0.001
Schistosoma mansoni hypothetical protein 0.0083 0.0069 0.0069
Loa Loa (eye worm) MH2 domain-containing protein 0.0251 0.023 0.023
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0159 0.0142 1
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0094 0.008 0.008
Schistosoma mansoni phosphatidylserine receptor 0.0041 0.0029 0.0029
Echinococcus multilocularis lysosomal alpha glucosidase 0.0179 0.0162 0.0162
Brugia malayi Intermediate filament tail domain containing protein 0.0057 0.0044 0.0044
Schistosoma mansoni short chain dehydrogenase 0.0012 0.0001 0.0001
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0044 0.0032 0.1146
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.001 0.001
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0143 0.0127 0.581
Loa Loa (eye worm) oxidoreductase 0.0012 0.0001 0.0001
Brugia malayi jmjC domain containing protein 0.0156 0.0139 0.0139
Echinococcus granulosus geminin 0.0361 0.0336 0.0336
Echinococcus granulosus neuropeptide s receptor 0.0971 0.0923 0.0923
Brugia malayi Probable ClpP-like protease 0.0159 0.0142 0.0142
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0017 0.0006 0.0006
Loa Loa (eye worm) latrophilin receptor protein 2 0.0083 0.0069 0.0069
Schistosoma mansoni caspase-3 (C14 family) 0.0116 0.0101 0.0101
Echinococcus granulosus carbonyl reductase 1 0.0012 0.0001 0.0001
Schistosoma mansoni smad 0.0017 0.0006 0.0006
Onchocerca volvulus Huntingtin homolog 0.0257 0.0237 1
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0032 0.1146
Echinococcus granulosus phd:f box containing protein 0.0041 0.0029 0.0029
Brugia malayi intermediate filament protein 0.0057 0.0044 0.0044
Loa Loa (eye worm) hypothetical protein 0.0041 0.0029 0.0029
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0021 0.001 0.001
Echinococcus granulosus fatty acid binding protein FABP2 0.0081 0.0067 0.0067
Onchocerca volvulus Huntingtin homolog 0.0257 0.0237 1
Mycobacterium ulcerans aldehyde dehydrogenase 0.0123 0.0108 0.7584
Onchocerca volvulus 0.0037 0.0025 0.1031
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0098 0.0083 0.0083
Trichomonas vaginalis alpha-glucosidase, putative 0.004 0.0028 0.0996
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0043 0.0031 0.0031
Trypanosoma cruzi metacaspase, putative 0.0044 0.0032 0.3916
Echinococcus multilocularis conserved hypothetical protein 0.0012 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0037 0.0025 0.0025
Trichomonas vaginalis set domain proteins, putative 0.0236 0.0216 0.7995
Echinococcus granulosus alpha 16 mannosyl glycoprotein 1.042 1 1
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0159 0.0142 1
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0015 0.0004 0.0363
Brugia malayi PHD-finger family protein 0.0029 0.0017 0.0017
Echinococcus multilocularis ecdysone induced protein 78C 0.0021 0.001 0.001
Onchocerca volvulus Alhambra homolog 0.0029 0.0017 0.0706
Echinococcus granulosus hypothetical protein 0.0012 0.0001 0.0001
Echinococcus multilocularis Dehydrogenase:reductase SDR family 0.0012 0.0001 0.0001
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0083 0.0069 0.0069
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0048 0.0036 0.0036
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0025 0.0902
Trypanosoma cruzi metacaspase 5, putative 0.0044 0.0032 0.3916
Echinococcus multilocularis dnaJ subfamily B 0.0423 0.0395 0.0395
Schistosoma mansoni hypothetical protein 0.0029 0.0017 0.0017
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0001 0.0001
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0019 0.0008 0.0645
Echinococcus multilocularis lysine specific demethylase 6a 0.0041 0.0029 0.0029
Echinococcus multilocularis dna polymerase eta 0.0044 0.0032 0.0032
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0021 0.001 0.001
Schistosoma mansoni hypothetical protein 0.0361 0.0336 0.0336
Echinococcus multilocularis fatty acid binding protein FABP2 0.0123 0.0107 0.0107
Loa Loa (eye worm) hypothetical protein 0.0237 0.0217 0.0216
Echinococcus multilocularis caspase 8 0.0044 0.0032 0.0032
Brugia malayi Hypothetical oxidoreductase F56D1.5 0.0012 0.0001 0.0001
Echinococcus granulosus dnaJ subfamily B 0.0423 0.0395 0.0395
Echinococcus multilocularis bloom syndrome protein 0.0024 0.0012 0.0012
Schistosoma mansoni coup transcription factor 0.0021 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0012 0.0001 0.0001
Giardia lamblia DINP protein human, muc B family 0.0019 0.0008 0.0256
Schistosoma mansoni aldehyde dehydrogenase 0.0123 0.0108 0.0108
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0116 0.0101 0.0101
Trichomonas vaginalis penicillin-binding protein, putative 0.0037 0.0025 0.0902
Toxoplasma gondii ABC1 family protein 0.0037 0.0025 0.1723
Brugia malayi hypothetical protein 0.0016 0.0005 0.0005
Echinococcus multilocularis apoptotic protease activating factor 1 0.0041 0.0029 0.0029
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.004 0.0028 0.1903
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0001 0.0001
Echinococcus granulosus steroid dehydrogenase 0.0012 0.0001 0.0001
Mycobacterium tuberculosis Conserved hypothetical protein 0.0019 0.0008 0.0318
Trypanosoma brucei unspecified product 0.0019 0.0008 0.0875
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0008 0.0489
Loa Loa (eye worm) oxidoreductase 0.0012 0.0001 0.0001
Onchocerca volvulus 0.0021 0.001 0.0383
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0001 0.0001
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0008 0.0875
Schistosoma mansoni hypothetical protein 0.0048 0.0036 0.0036
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.001 0.001
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0008 0.0875
Loa Loa (eye worm) jmjC domain-containing protein 0.0041 0.0029 0.0029
Brugia malayi MH2 domain containing protein 0.0017 0.0006 0.0006
Schistosoma mansoni intermediate filament proteins 0.0057 0.0044 0.0044
Schistosoma mansoni smad1 5 8 and 0.0017 0.0006 0.0006
Mycobacterium tuberculosis Conserved protein 0.0037 0.0025 0.1122
Mycobacterium ulcerans lipase LipD 0.0037 0.0025 0.1723
Echinococcus granulosus JmjC domain containing protein 4 0.0041 0.0029 0.0029
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0044 0.0032 0.1146
Loa Loa (eye worm) hypothetical protein 0.0012 0.0001 0.0001
Mycobacterium ulcerans hypothetical protein 0.0037 0.0025 0.1723
Schistosoma mansoni short chain dehydrogenase 0.0012 0.0001 0.0001
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0011 0.0000074247 0.0000074247
Trichomonas vaginalis esterase, putative 0.0037 0.0025 0.0902
Mycobacterium tuberculosis Probable lipase LipD 0.0037 0.0025 0.1122
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0116 0.0101 0.0101
Echinococcus multilocularis lysine specific demethylase 5A 0.0155 0.0138 0.0138
Schistosoma mansoni alpha-glucosidase 0.0154 0.0138 0.0138
Loa Loa (eye worm) hypothetical protein 0.0121 0.0105 0.0105
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0017 0.118
Brugia malayi Calcitonin receptor-like protein seb-1 0.0263 0.0242 0.0242
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0019 0.0008 0.0256
Echinococcus granulosus survival motor neuron protein 1 0.0237 0.0217 0.0217
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.004 0.0028 0.0996
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.001 0.001
Trichomonas vaginalis alpha-glucosidase, putative 0.0015 0.0004 0.0106
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0055 0.0042 0.2917
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0021 0.001 0.001
Mycobacterium ulcerans esterase/lipase LipP 0.0037 0.0025 0.1723
Schistosoma mansoni carbonyl reductase 0.0012 0.0001 0.0001
Mycobacterium tuberculosis Probable hydrolase 0.0037 0.0025 0.1122
Trichomonas vaginalis alpha-glucosidase, putative 0.0015 0.0004 0.0106
Echinococcus granulosus lysosomal alpha glucosidase 0.0179 0.0162 0.0162
Echinococcus multilocularis cpg binding protein 0.0031 0.0019 0.0019
Brugia malayi Isocitrate dehydrogenase 0.0016 0.0004 0.0004
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0021 0.001 0.001
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0016 0.0004 0.0004

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

10 literature references were collected for this gene.

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