Detailed information for compound 676766

Basic information

Technical information
  • TDR Targets ID: 676766
  • Name: N-(1,3-benzothiazol-2-yl)-4-(4-chlorophenoxy) butanamide
  • MW: 346.831 | Formula: C17H15ClN2O2S
  • H donors: 1 H acceptors: 2 LogP: 4.47 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: Clc1ccc(cc1)OCCCC(=O)Nc1nc2c(s1)cccc2
  • InChi: 1S/C17H15ClN2O2S/c18-12-7-9-13(10-8-12)22-11-3-6-16(21)20-17-19-14-4-1-2-5-15(14)23-17/h1-2,4-5,7-10H,3,6,11H2,(H,19,20,21)
  • InChiKey: ZBWXFGQUIVSACZ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • N-(1,3-benzothiazol-2-yl)-4-(4-chlorophenoxy)butyramide
  • EU-0081889
  • ST5016777
  • BAS 03311296
  • N-Benzothiazol-2-yl-4-(4-chloro-phenoxy)-butyramide
  • ZINC01773653

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.027 0.0964 0.1632
Echinococcus multilocularis solute carrier family 5 0.0115 0.037 0.0397
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.003 0.0043 0.0137
Schistosoma mansoni intermediate filament proteins 0.0027 0.0031 0.0053
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0073 0.0207 0.0351
Brugia malayi beta-lactamase family protein 0.0412 0.1505 0.4486
Schistosoma mansoni steroid hormone receptor ad4bp 0.0073 0.0207 0.0351
Loa Loa (eye worm) acetyltransferase 0.0149 0.0499 0.0846
Schistosoma mansoni cpg binding protein 0.0121 0.0391 0.0663
Mycobacterium leprae possible long-chain acyl-CoA synthase 0.0818 0.3058 1
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0073 0.0207 0.0617
Trypanosoma brucei glucose transporter, putative 0.0033 0.0056 0.0368
Echinococcus granulosus Polycystic kidney disease protein 0.004 0.008 0.0136
Loa Loa (eye worm) pyruvate kinase 0.0067 0.0185 0.0312
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0159 0.0538 0.3223
Toxoplasma gondii isocitrate dehydrogenase 0.0032 0.0051 0.0335
Echinococcus multilocularis acetylcholinesterase 0.007 0.0198 0.0212
Echinococcus granulosus serine protein kinase ATM 0.0026 0.0027 0.0045
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0073 0.0207 0.0351
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0073 0.0207 0.0351
Trypanosoma cruzi polo-like protein kinase, putative 0.01 0.031 0.0999
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0032 0.0051 0.0055
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0034 0.006 0.0064
Brugia malayi latrophilin 2 splice variant baaae 0.0344 0.1246 0.3712
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.003 0.0043 0.0282
Entamoeba histolytica acyl-CoA synthetase, putative 0.0078 0.0227 0.1507
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.003 0.0043 0.0282
Entamoeba histolytica acyl-CoA synthetase, putative 0.0078 0.0227 0.1507
Echinococcus granulosus mitogen activated protein kinase 0.0111 0.0352 0.0596
Onchocerca volvulus 0.0061 0.0163 0.0779
Trypanosoma cruzi hexose transporter, putative 0.0033 0.0056 0.0179
Leishmania major alpha glucosidase II subunit, putative 0.0153 0.0514 0.1679
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0078 0.0227 0.0732
Schistosoma mansoni hypothetical protein 0.0159 0.0539 0.0912
Loa Loa (eye worm) hypothetical protein 0.0412 0.1505 0.255
Trichomonas vaginalis DNA polymerase eta, putative 0.004 0.0083 0.0483
Echinococcus granulosus calcium dependent protein kinase 0.0031 0.0046 0.0078
Trichomonas vaginalis glucosylceramidase, putative 0.0177 0.0608 0.3543
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0061 0.0163 0.1078
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0073 0.0207 0.0351
Entamoeba histolytica hypothetical protein 0.0412 0.1505 1
Giardia lamblia Lysyl-tRNA synthetase 0.0024 0.002 0.0566
Schistosoma mansoni glucose transport protein 0.0107 0.0337 0.0571
Onchocerca volvulus Pyruvate kinase homolog 0.0067 0.0185 0.091
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0111 0.0352 0.1136
Echinococcus granulosus importin subunit beta 1 0.0146 0.0489 0.0827
Brugia malayi F/Y-rich N-terminus family protein 0.0056 0.0144 0.0428
Trichomonas vaginalis glucosylceramidase, putative 0.027 0.0964 0.5618
Treponema pallidum exodeoxyribonuclease (exoA) 0.0077 0.0223 0.3652
Brugia malayi Pyruvate kinase, muscle isozyme 0.0067 0.0185 0.0549
Brugia malayi hypothetical protein 0.004 0.008 0.0239
Echinococcus granulosus phd:f box containing protein 0.0019 0.0001 0.0001
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0073 0.0207 0.0617
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0028 0.0163
Brugia malayi ImpB/MucB/SamB family protein 0.004 0.0083 0.0247
Plasmodium vivax SET domain protein, putative 0.0061 0.0163 0.097
Echinococcus multilocularis importin 5 0.0028 0.0035 0.0037
Loa Loa (eye worm) hypothetical protein 0.0412 0.1505 0.255
Echinococcus granulosus neuropeptide s receptor 0.0502 0.1851 0.3135
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0032 0.0051 0.0087
Brugia malayi CXXC zinc finger family protein 0.0114 0.0366 0.1091
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0078 0.0227 0.0723
Echinococcus multilocularis geminin 0.1428 0.5392 0.5792
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0077 0.0223 0.024
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0078 0.0227 0.0221
Loa Loa (eye worm) hypothetical protein 0.0412 0.1505 0.255
Schistosoma mansoni lamin 0.0027 0.0031 0.0053
Onchocerca volvulus Glucosylceramidase homolog 0.0177 0.0608 0.3424
Mycobacterium leprae Probable lipase LipE 0.0412 0.1505 0.4912
Mycobacterium tuberculosis Probable lipase LipD 0.0412 0.1505 0.15
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0412 0.1505 0.15
Trypanosoma cruzi hypothetical protein, conserved 0.0153 0.0514 0.1657
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0034 0.006 0.0064
Schistosoma mansoni nuclear hormone receptor 0.0034 0.006 0.0102
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0195 0.0677 0.2196
Trichomonas vaginalis ap endonuclease, putative 0.0077 0.0223 0.1301
Plasmodium vivax hypothetical protein, conserved 0.0412 0.1505 0.9034
Plasmodium falciparum calcium-dependent protein kinase 2 0.0034 0.0059 0.0349
Brugia malayi Glycosyl hydrolases family 31 protein 0.0153 0.0514 0.153
Trichomonas vaginalis hypothetical protein 0.0028 0.0035 0.0202
Schistosoma mansoni ap endonuclease 0.0077 0.0223 0.0378
Loa Loa (eye worm) transcription factor SMAD2 0.0237 0.0834 0.1413
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0078 0.0227 0.1507
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0026 0.0029 0.0166
Mycobacterium ulcerans acyl-CoA synthetase 0.0078 0.0227 0.0671
Trypanosoma cruzi trypanothione reductase, putative 0.0086 0.0257 0.0828
Brugia malayi Cam kinase protein 1 0.0034 0.0059 0.0175
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0038 0.0076 0.0128
Plasmodium falciparum calcium-dependent protein kinase 4 0.0034 0.0059 0.0349
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0034 0.0059 0.01
Leishmania major glycosyl hydrolase-like protein 0.0057 0.0147 0.0479
Plasmodium vivax transportin, putative 0.0028 0.0035 0.0204
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0159 0.0538 0.1741
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0038 0.0076 0.0129
Echinococcus granulosus pyruvate kinase 0.0034 0.006 0.0102
Brugia malayi jmjC domain containing protein 0.0019 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0412 0.1505 0.255
Trichomonas vaginalis penicillin-binding protein, putative 0.0412 0.1505 0.8776
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0073 0.0207 0.1044
Plasmodium vivax pyruvate kinase 2, putative 0.0034 0.006 0.0356
Plasmodium vivax thioredoxin reductase, putative 0.0086 0.0257 0.1536
Loa Loa (eye worm) hypothetical protein 0.0412 0.1505 0.255
Brugia malayi beta-lactamase family protein 0.0412 0.1505 0.4486
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0111 0.0352 0.0596
Mycobacterium tuberculosis Conserved hypothetical protein 0.0154 0.0517 0.0511
Brugia malayi jmjC domain containing protein 0.0019 0.0001 0.0002
Leishmania major acetyl-CoA synthetase, putative 0.0078 0.0227 0.0742
Loa Loa (eye worm) hypothetical protein 0.0034 0.006 0.0102
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0034 0.006 0.0064
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.003 0.0043 0.0126
Trypanosoma cruzi pyruvate kinase 2, putative 0.0067 0.0185 0.0595
Trypanosoma cruzi hypothetical protein, conserved 0.0153 0.0514 0.1657
Echinococcus granulosus sodium:glucose cotransporter 2 0.0115 0.037 0.0626
Entamoeba histolytica HEAT repeat domain containing protein 0.0028 0.0035 0.0231
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0028 0.0163
Echinococcus granulosus mixed lineage leukemia protein mll 0.0031 0.0046 0.0077
Plasmodium falciparum thioredoxin reductase 0.003 0.0043 0.025
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0041 0.0086 0.057
Trichomonas vaginalis glucose transporter, putative 0.0033 0.0056 0.0323
Loa Loa (eye worm) acetylcholinesterase 1 0.007 0.0198 0.0334
Trypanosoma cruzi hypothetical protein, conserved 0.0412 0.1505 0.4857
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0159 0.0539 0.0578
Loa Loa (eye worm) importin-beta domain-containing protein 0.0028 0.0035 0.0059
Toxoplasma gondii isocitrate dehydrogenase 0.0032 0.0051 0.0335
Mycobacterium ulcerans hypothetical protein 0.0412 0.1505 0.4483
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.003 0.0043 0.0282
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0078 0.0227 0.0671
Loa Loa (eye worm) kap beta 3 protein 0.0028 0.0035 0.0059
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0032 0.0051 0.0299
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0159 0.0538 0.3571
Schistosoma mansoni nuclear hormone receptor 0.0034 0.006 0.0102
Schistosoma mansoni alpha-glucosidase 0.0593 0.2197 0.3721
Echinococcus granulosus mitogen activated protein kinase 3 0.0111 0.0352 0.0596
Trypanosoma brucei DNA polymerase kappa, putative 0.0028 0.0035 0.0233
Brugia malayi hypothetical protein 0.0033 0.0054 0.0161
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0073 0.0207 0.0617
Echinococcus multilocularis calcium dependent protein kinase 0.0031 0.0046 0.005
Giardia lamblia PHD finger protein 15 0.0058 0.0152 0.431
Schistosoma mansoni cpg binding protein 0.0121 0.0391 0.0663
Onchocerca volvulus 0.0412 0.1505 0.8753
Plasmodium falciparum importin beta, putative 0.0146 0.0489 0.2929
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0037 0.0072 0.0231
Brugia malayi Isocitrate dehydrogenase 0.0032 0.0051 0.015
Schistosoma mansoni rab6-interacting 0.004 0.008 0.0136
Leishmania major lysyl-tRNA synthetase, putative 0.0024 0.002 0.0065
Trichomonas vaginalis sucrase-isomaltase, putative 0.0153 0.0514 0.2993
Echinococcus multilocularis General substrate transporter 0.0092 0.028 0.03
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.003 0.0043 0.0137
Trichomonas vaginalis glutathione reductase, putative 0.003 0.0043 0.0247
Trichomonas vaginalis sugar transporter, putative 0.0033 0.0056 0.0323
Loa Loa (eye worm) hypothetical protein 0.0034 0.006 0.0102
Schistosoma mansoni phd/f-box containing protein 0.0019 0.0001 0.0002
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0159 0.0538 0.1597
Loa Loa (eye worm) hypothetical protein 0.0086 0.0258 0.0437
Echinococcus granulosus JmjC domain containing protein 4 0.0019 0.0001 0.0001
Echinococcus granulosus histone acetyltransferase KAT2B 0.0044 0.0097 0.0164
Schistosoma mansoni hypothetical protein 0.0023 0.0016 0.0027
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0159 0.0538 0.3571
Onchocerca volvulus 0.0115 0.037 0.201
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0019 0.0001 0.0005
Echinococcus multilocularis peptidase Clp (S14 family) 0.0104 0.0328 0.0352
Trypanosoma brucei ULK family serine/threonine-protein kinase, putative 0.0031 0.0048 0.0315
Onchocerca volvulus 0.0078 0.0227 0.1162
Toxoplasma gondii lysine-tRNA ligase 0.0024 0.002 0.0132
Trichomonas vaginalis glucose transporter, putative 0.0033 0.0056 0.0323
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0073 0.0207 0.0617
Trypanosoma brucei glucose transporter, putative 0.0033 0.0056 0.0368
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0107 0.0337 0.0362
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0078 0.0227 0.1357
Brugia malayi Pre-SET motif family protein 0.0411 0.15 0.4469
Loa Loa (eye worm) jmjC domain-containing protein 0.012 0.0389 0.0659
Brugia malayi photoreceptor-specific nuclear receptor 0.0073 0.0207 0.0617
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0032 0.0051 0.0163
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0073 0.0207 0.0617
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.003 0.0043 0.0121
Loa Loa (eye worm) hypothetical protein 0.0159 0.0538 0.091
Trypanosoma brucei glucose transporter, putative 0.0033 0.0056 0.0368
Toxoplasma gondii exonuclease III APE 0.0077 0.0223 0.1483
Plasmodium falciparum calcium-dependent protein kinase 1 0.0034 0.0059 0.0349
Leishmania major dihydrolipoamide dehydrogenase, putative 0.003 0.0043 0.0139
Entamoeba histolytica hypothetical protein 0.0412 0.1505 1
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0078 0.0227 0.1507
Leishmania major 4-coumarate:coa ligase-like protein 0.0078 0.0227 0.0742
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0159 0.0538 0.1597
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0086 0.0257 0.0251
Plasmodium falciparum protein kinase 7 0.0303 0.1087 0.6522
Schistosoma mansoni hypothetical protein 0.0107 0.0337 0.0571
Echinococcus granulosus survival motor neuron protein 1 0.0256 0.0908 0.1538
Brugia malayi RNA, U transporter 1 0.0416 0.152 0.453
Loa Loa (eye worm) hypothetical protein 0.0159 0.0539 0.0912
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0032 0.0051 0.0086
Brugia malayi hypothetical protein 0.0086 0.0258 0.0769
Brugia malayi Intermediate filament tail domain containing protein 0.0027 0.0031 0.0093
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0159 0.0539 0.1604
Toxoplasma gondii HEAT repeat-containing protein 0.0028 0.0035 0.023
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0026 0.0028 0.0163
Brugia malayi AMP-binding enzyme family protein 0.0896 0.3356 1
Brugia malayi ImpB/MucB/SamB family protein 0.004 0.0083 0.0247
Loa Loa (eye worm) beta-lactamase 0.0412 0.1505 0.255
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0083 0.0267
Mycobacterium ulcerans DNA polymerase IV 0.004 0.0083 0.0242
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0292 0.1045 0.3373
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.003 0.0043 0.025
Trichomonas vaginalis sugar transporter, putative 0.0033 0.0056 0.0323
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0028 0.0163
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0032 0.0051 0.0165
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0034 0.0059 0.0063
Echinococcus multilocularis dna polymerase eta 0.004 0.0083 0.0089
Brugia malayi Carboxylesterase family protein 0.007 0.0198 0.0588
Trypanosoma brucei trypanothione reductase 0.0086 0.0257 0.1705
Echinococcus multilocularis PHD finger protein rhinoceros 0.0058 0.0152 0.0163
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0044 0.0097 0.0641
Schistosoma mansoni hypothetical protein 0.0019 0.0002 0.0003
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0028 0.0163
Loa Loa (eye worm) hypothetical protein 0.0412 0.1505 0.255
Brugia malayi hypothetical protein 0.0034 0.006 0.0179
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0083 0.0551
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0073 0.0207 0.0351
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0078 0.0227 0.0221
Mycobacterium ulcerans hypothetical protein 0.0154 0.0517 0.1536
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0034 0.006 0.0064
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0078 0.0227 0.0221
Schistosoma mansoni ran 0.0087 0.0262 0.0444
Loa Loa (eye worm) cytochrome P450 family protein 0.0048 0.0113 0.0191
Echinococcus multilocularis jumonji domain containing protein 0.0081 0.0239 0.0257
Loa Loa (eye worm) glutathione reductase 0.0086 0.0257 0.0435
Brugia malayi MAP kinase sur-1 0.0111 0.0352 0.1049
Trichomonas vaginalis alpha-glucosidase, putative 0.0057 0.0147 0.0854
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0026 0.0027 0.0079
Brugia malayi tailless protein 0.0034 0.006 0.0179
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0031 0.0046 0.0049
Trichomonas vaginalis importin beta-1, putative 0.0119 0.0383 0.2231
Brugia malayi hypothetical protein 0.0256 0.0908 0.2706
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0109 0.0346 0.0586
Brugia malayi nuclear hormone receptor family member nhr-6 0.0034 0.006 0.0179
Echinococcus granulosus lysyl tRNA synthetase 0.0024 0.002 0.0034
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0024 0.002 0.0064
Plasmodium falciparum hexose transporter 0.0107 0.0337 0.2019
Giardia lamblia Histone acetyltransferase GCN5 0.004 0.0083 0.2346
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0896 0.3356 1
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0153 0.0514 0.3412
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0287 0.1027 0.1739
Trypanosoma brucei glucose transporter, putative 0.0033 0.0056 0.0368
Brugia malayi Glycosyl hydrolases family 31 protein 0.0689 0.2563 0.7639
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0078 0.0227 0.0384
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0083 0.0551
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0078 0.0227 0.0723
Entamoeba histolytica hypothetical protein 0.0119 0.0383 0.2543
Mycobacterium tuberculosis Probable dehydrogenase 0.0195 0.0677 0.0671
Loa Loa (eye worm) doublecortin family protein 0.004 0.008 0.0136
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0073 0.0207 0.0617
Schistosoma mansoni inositol transporter 0.0115 0.037 0.0626
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0073 0.0207 0.0351
Echinococcus multilocularis neuropeptide s receptor 0.0502 0.1851 0.1988
Mycobacterium ulcerans acyl-CoA synthetase 0.0078 0.0227 0.0671
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0078 0.0227 0.0384
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0077 0.0223 0.3652
Brugia malayi AF-10 protein 0.0019 0.0002 0.0005
Brugia malayi nuclear hormone receptor 0.0034 0.006 0.0179
Trypanosoma brucei unspecified product 0.004 0.0083 0.0551
Brugia malayi jmjC domain containing protein 0.0191 0.0659 0.1963
Plasmodium falciparum pyruvate kinase 2 0.0034 0.006 0.0356
Onchocerca volvulus 0.0034 0.006 0.0171
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0032 0.0051 0.0087
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.003 0.0043 0.0137
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0078 0.0227 0.0671
Schistosoma mansoni mixed-lineage leukemia protein mll 0.005 0.0119 0.0201
Echinococcus multilocularis lysosomal alpha glucosidase 0.0689 0.2563 0.2754
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0034 0.0059 0.01
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0078 0.0227 0.0221
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.003 0.0043 0.0282
Schistosoma mansoni importin beta-1 0.0146 0.0489 0.0828
Brugia malayi intermediate filament protein 0.0027 0.0031 0.0093
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0412 0.1505 0.4483
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0503 0.1855 0.5529
Echinococcus multilocularis lipoxygenase domain containing protein 0.004 0.008 0.0086
Schistosoma mansoni nuclear receptor 0.0034 0.006 0.0102
Entamoeba histolytica hypothetical protein 0.0412 0.1505 1
Plasmodium falciparum histone acetyltransferase GCN5 0.004 0.0083 0.0491
Loa Loa (eye worm) hypothetical protein 0.004 0.0083 0.014
Loa Loa (eye worm) hypothetical protein 0.0078 0.0227 0.0384
Echinococcus multilocularis pyruvate kinase 0.0067 0.0185 0.0198
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0037 0.0072 0.0231
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0078 0.0227 0.0221
Brugia malayi Pyruvate kinase, M2 isozyme 0.0067 0.0185 0.0549
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0083 0.0551
Plasmodium falciparum calcium-dependent protein kinase 5 0.0034 0.0059 0.0349
Mycobacterium leprae Probable pyruvate kinase PykA 0.0067 0.0185 0.0584
Trypanosoma cruzi hypothetical protein, conserved 0.0412 0.1505 0.4857
Echinococcus granulosus cpg binding protein 0.0121 0.0391 0.0662
Giardia lamblia Pyruvate kinase 0.0067 0.0185 0.5237
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0078 0.0227 0.0671
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0019 0.0001 0.0005
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0078 0.0227 0.0671
Trypanosoma cruzi hexose transporter, putative 0.0033 0.0056 0.0179
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0061 0.0163 0.0275
Echinococcus granulosus geminin 0.1428 0.5392 0.9134
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0078 0.0227 0.0221
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0067 0.0186 0.0179
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0191 0.0659 0.1116
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0032 0.0051 0.0335
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.01 0.031 0.1013
Plasmodium vivax importin-beta 2, putative 0.0146 0.0489 0.2929
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0153 0.0514 0.087
Echinococcus granulosus lysine specific demethylase 6a 0.0019 0.0001 0.0001
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0034 0.006 0.0102
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0107 0.0337 0.0362
Loa Loa (eye worm) hypothetical protein 0.0038 0.0076 0.0128
Plasmodium vivax hypothetical protein, conserved 0.0058 0.0152 0.0906
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0067 0.0185 0.0178
Schistosoma mansoni alpha-glucosidase 0.0593 0.2197 0.3721
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0078 0.0227 0.0221
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0073 0.0207 0.0351
Trypanosoma brucei pyruvate kinase 1, putative 0.0067 0.0185 0.1225
Loa Loa (eye worm) hypothetical protein 0.0073 0.0207 0.0351
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0078 0.0227 0.1507
Leishmania major pyruvate kinase 0.0067 0.0185 0.0603
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.01 0.031 0.0525
Loa Loa (eye worm) CXXC zinc finger family protein 0.0114 0.0366 0.062
Trichomonas vaginalis D-aminoacylase, putative 0.0412 0.1505 0.8776
Brugia malayi exodeoxyribonuclease III family protein 0.0077 0.0223 0.0665
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0412 0.1505 0.255
Trypanosoma cruzi cytochrome P450, putative 0.0019 0.0002 0.0006
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0022 0.0012 0.0037
Plasmodium vivax hypothetical protein, conserved 0.0026 0.0029 0.0166
Toxoplasma gondii hypothetical protein 0.0047 0.0109 0.0723
Trypanosoma brucei importin beta-1 subunit, putative 0.0146 0.0489 0.3245
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.003 0.0043 0.0282
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0034 0.0059 0.0175
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0159 0.0538 1
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0087 0.0262 0.7437
Entamoeba histolytica protein kinase, putative 0.0034 0.0059 0.0391
Leishmania major hypothetical protein, conserved 0.0028 0.0035 0.0113
Schistosoma mansoni ran 0.0087 0.0262 0.0444
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0077 0.0223 0.066
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0111 0.0352 0.1151
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0119 0.0383 0.2231
Echinococcus multilocularis pyruvate kinase 0.0034 0.006 0.0064
Trichomonas vaginalis glucosylceramidase, putative 0.0177 0.0608 0.3543
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0026 0.0027 0.0045
Schistosoma mansoni thyroid hormone receptor 0.0073 0.0207 0.0351
Echinococcus multilocularis pyruvate kinase 0.0034 0.006 0.0064
Mycobacterium ulcerans acyl-CoA synthetase 0.0078 0.0227 0.0671
Echinococcus granulosus neuropeptide receptor A26 0.0502 0.1851 0.3135
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0083 0.0551
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0073 0.0207 0.0617
Brugia malayi Importin beta-1 subunit 0.0146 0.0489 0.1456
Plasmodium falciparum proline--tRNA ligase 0.0037 0.0072 0.0425
Echinococcus granulosus Nuclear hormone receptor HR96 0.0034 0.006 0.0102
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0078 0.0227 0.0671
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0078 0.0227 0.0244
Trypanosoma brucei glucose transporter, putative 0.0033 0.0056 0.0368
Mycobacterium ulcerans glutaminase 0.0303 0.1089 0.3242
Schistosoma mansoni cpg binding protein 0.0114 0.0366 0.0621
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0023 0.0016 0.0027
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0073 0.0207 0.0351
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0195 0.0677 0.0671
Echinococcus multilocularis survival motor neuron protein 1 0.0256 0.0908 0.0976
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0041 0.0086 0.0277
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0117 0.0376 0.037
Onchocerca volvulus 0.0086 0.0257 0.134
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0138 0.0457 0.1495
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0061 0.0163 0.0275
Entamoeba histolytica protein kinase, putative 0.0034 0.0059 0.0391
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0055 0.0139 0.1941
Schistosoma mansoni protein kinase 0.0034 0.0059 0.01
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0034 0.0059 0.0063
Trichomonas vaginalis alpha-glucosidase, putative 0.0153 0.0514 0.2993
Loa Loa (eye worm) hypothetical protein 0.0034 0.006 0.0102
Trypanosoma brucei cytochrome P450, putative 0.0019 0.0002 0.0012
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.2451 0.9308 1
Echinococcus granulosus peptidase Clp S14 family 0.0104 0.0328 0.0555
Brugia malayi Carboxylesterase family protein 0.007 0.0198 0.0588
Brugia malayi hypothetical protein 0.0038 0.0076 0.0226
Leishmania major glucose transporter/membrane transporter D2, putative 0.0033 0.0056 0.0181
Trypanosoma brucei glucose transporter, putative 0.0033 0.0056 0.0368
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0153 0.0514 0.2993
Echinococcus multilocularis lysosomal alpha glucosidase 0.0689 0.2563 0.2754
Loa Loa (eye worm) hypothetical protein 0.0026 0.003 0.005
Loa Loa (eye worm) hypothetical protein 0.007 0.0198 0.0334
Echinococcus multilocularis pyruvate kinase 0.0053 0.0131 0.014
Echinococcus granulosus lysine specific demethylase 5A 0.0077 0.0224 0.0379
Loa Loa (eye worm) MH2 domain-containing protein 0.0237 0.0834 0.1413
Loa Loa (eye worm) hypothetical protein 0.0024 0.002 0.0034
Toxoplasma gondii PHD-finger domain-containing protein 0.0019 0.0002 0.0011
Echinococcus granulosus histone lysine methyltransferase setb 0.0061 0.0163 0.0275
Schistosoma mansoni transcription factor LCR-F1 0.0412 0.1505 0.2549
Trypanosoma cruzi pantothenate kinase subunit, putative 0.0026 0.003 0.0096
Entamoeba histolytica hypothetical protein 0.0412 0.1505 1
Onchocerca volvulus 0.0412 0.1505 0.8753
Mycobacterium tuberculosis Probable lipase LipE 0.0412 0.1505 0.15
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0057 0.0147 0.0854
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0034 0.0059 0.0391
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0117 0.0376 0.0637
Plasmodium falciparum ataxin-2 like protein, putative 0.0051 0.0123 0.0734
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.003 0.0043 0.0072
Schistosoma mansoni loxhd1 0.004 0.008 0.0136
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0073 0.0207 0.0351
Brugia malayi Sodium:solute symporter family protein 0.0115 0.037 0.1101
Trichomonas vaginalis CAMK family protein kinase 0.01 0.031 0.1806
Echinococcus granulosus sodium coupled monocarboxylate transporter 1 0.0115 0.037 0.0626
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0032 0.0051 0.0044
Trichomonas vaginalis CAMK family protein kinase 0.01 0.031 0.1806
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0111 0.0352 0.1136
Echinococcus granulosus beta LACTamase domain containing family member 0.0412 0.1505 0.255
Loa Loa (eye worm) hypothetical protein 0.0034 0.006 0.0102
Loa Loa (eye worm) hypothetical protein 0.0086 0.0258 0.0437
Echinococcus multilocularis lipoxygenase domain containing protein 0.004 0.008 0.0086
Loa Loa (eye worm) steroid hormone receptor 0.0073 0.0207 0.0351
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0078 0.0227 0.0671
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0896 0.3356 0.5684
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0503 0.1855 0.3143
Loa Loa (eye worm) hypothetical protein 0.0344 0.1246 0.211
Loa Loa (eye worm) hypothetical protein 0.0032 0.0051 0.0087
Plasmodium falciparum calcium-dependent protein kinase 3 0.0034 0.0059 0.0349
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0117 0.0376 0.1115
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0032 0.0051 0.0299
Plasmodium falciparum ataxin-2 like protein, putative 0.0051 0.0123 0.0734
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0153 0.0514 0.2993
Leishmania major 4-coumarate:coa ligase-like protein 0.0078 0.0227 0.0742
Trichomonas vaginalis glucosylceramidase, putative 0.027 0.0964 0.5618
Schistosoma mansoni survival motor neuron protein 0.0052 0.0129 0.0218
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0287 0.1027 0.1739
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0032 0.0051 0.0335
Trichomonas vaginalis alpha-glucosidase, putative 0.0153 0.0514 0.2993
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0412 0.1505 0.1616
Trichomonas vaginalis glucosylceramidase, putative 0.0187 0.0644 0.3756
Brugia malayi Nuclear hormone receptor-like 1 0.0073 0.0207 0.0617
Leishmania major pyruvate kinase 0.0067 0.0185 0.0603
Loa Loa (eye worm) hypothetical protein 0.0034 0.006 0.0102
Mycobacterium tuberculosis Probable reductase 0.0195 0.0677 0.0671
Trypanosoma cruzi cytochrome P450, putative 0.0019 0.0002 0.0006
Brugia malayi hypothetical protein 0.0038 0.0076 0.0226
Echinococcus granulosus Nuclear hormone receptor HR96 0.0034 0.006 0.0102
Loa Loa (eye worm) jmjC domain-containing protein 0.0077 0.0224 0.0379
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0077 0.0223 0.0378
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0078 0.0227 0.1507
Plasmodium falciparum glutathione reductase 0.003 0.0043 0.025
Trichomonas vaginalis CAMK family protein kinase 0.0051 0.0123 0.0718
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0034 0.0059 0.0063
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0117 0.0376 0.1229
Brugia malayi GH02984p 0.0115 0.037 0.1101
Trichomonas vaginalis CMGC family protein kinase 0.0111 0.0352 0.2052
Trypanosoma brucei glycosyl hydrolase-like protein 0.0057 0.0147 0.0974
Loa Loa (eye worm) hypothetical protein 0.0078 0.0227 0.0384
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0087 0.0262 0.078
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0028 0.0163
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.003 0.0043 0.0046
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0032 0.0051 0.0153
Schistosoma mansoni serine/threonine protein kinase 0.0034 0.0059 0.01
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0034 0.0059 0.01
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0032 0.0051 0.0163
Mycobacterium ulcerans DNA polymerase IV 0.004 0.0083 0.0242
Loa Loa (eye worm) pyruvate kinase-PB 0.0047 0.0107 0.0181
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0034 0.006 0.0171
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0061 0.0163 0.0174
Entamoeba histolytica pyruvate kinase, putative 0.0047 0.0107 0.0712
Mycobacterium ulcerans acyl-CoA synthetase 0.0078 0.0227 0.0671
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0034 0.0059 0.039
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0083 0.0551
Echinococcus granulosus lamin dm0 0.0027 0.0031 0.0053
Loa Loa (eye worm) hypothetical protein 0.0256 0.0908 0.1538
Trichomonas vaginalis glucosylceramidase, putative 0.027 0.0964 0.5618
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0078 0.0227 0.0671
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0195 0.0677 0.0671
Trichomonas vaginalis glucosylceramidase, putative 0.0187 0.0644 0.3756
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0034 0.0059 0.0349
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0032 0.0051 0.0341
Schistosoma mansoni nuclear hormone receptor 0.0073 0.0207 0.0351
Onchocerca volvulus 0.0078 0.0227 0.1162
Entamoeba histolytica Ran family GTPase 0.0087 0.0262 0.174
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0078 0.0227 0.0221
Trichomonas vaginalis sugar transporter, putative 0.0033 0.0056 0.0323
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0078 0.0227 0.0676
Loa Loa (eye worm) latrophilin receptor protein 2 0.0159 0.0539 0.0912
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0117 0.0376 0.0404
Trypanosoma cruzi hexose transporter, putative 0.0033 0.0056 0.0179
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0078 0.0227 0.0221
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0104 0.0328 0.1054
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0087 0.0262 0.1567
Plasmodium vivax calcium-dependent protein kinase, putative 0.0034 0.0059 0.0349
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0038 0.0073 0.0078
Plasmodium vivax acetyl-CoA synthetase, putative 0.0078 0.0227 0.1357
Mycobacterium ulcerans lipase LipD 0.0412 0.1505 0.4483
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0138 0.0457 0.1475
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0287 0.1027 0.1103
Plasmodium vivax CDK-related protein kinase 6, putative 0.0454 0.1666 1
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0073 0.0207 0.0222
Loa Loa (eye worm) glutaminase 2 0.0303 0.1089 0.1845
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.004 0.0083 0.0089
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0038 0.0076 0.0081
Schistosoma mansoni serine/threonine protein kinase 0.01 0.031 0.0525
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0021 0.0009 0.0051
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0037 0.0072 0.0476
Brugia malayi Nuclear hormone receptor E75 0.0034 0.006 0.0179
Echinococcus granulosus snurportin 1 0.1561 0.5903 1
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.004 0.0083 0.0077
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0078 0.0227 0.0732
Brugia malayi nuclear receptor NHR-67 0.0034 0.006 0.0179
Brugia malayi Nuclear hormone receptor-like 1 0.0038 0.0076 0.0226
Echinococcus granulosus dna polymerase eta 0.004 0.0083 0.014
Echinococcus multilocularis jumonji domain containing 1A 0.0019 0.0001 0.0001
Trypanosoma cruzi trypanothione reductase, putative 0.003 0.0043 0.0137
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0111 0.0352 0.2339
Loa Loa (eye worm) hypothetical protein 0.0019 0.0001 0.0001
Schistosoma mansoni eyes absent homolog 0.0086 0.0258 0.0437
Schistosoma mansoni hypothetical protein 0.0344 0.1246 0.2111
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0038 0.0076 0.0128
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.003 0.0043 0.0139
Loa Loa (eye worm) hypothetical protein 0.0038 0.0076 0.0128
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0034 0.006 0.0102
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0078 0.0227 0.1507
Mycobacterium ulcerans pyruvate kinase 0.0067 0.0185 0.0544
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.003 0.0043 0.0137
Loa Loa (eye worm) PHD-finger family protein 0.0058 0.0152 0.0257
Schistosoma mansoni lamin 0.0027 0.0031 0.0053
Schistosoma mansoni jumonji domain containing protein 0.0152 0.0509 0.0862
Echinococcus granulosus pyruvate kinase 0.0067 0.0185 0.0312
Trypanosoma brucei DNA polymerase kappa, putative 0.0028 0.0035 0.0233
Brugia malayi MH2 domain containing protein 0.0237 0.0834 0.2486
Echinococcus granulosus GPCR family 2 0.0159 0.0539 0.0912
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0078 0.0227 0.0221
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0057 0.0147 0.0854
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0077 0.0223 0.072
Trichomonas vaginalis bromodomain-containing protein, putative 0.0044 0.0097 0.0563
Echinococcus granulosus carboxylesterase 5A 0.007 0.0198 0.0334
Echinococcus multilocularis lysine specific demethylase 5A 0.0071 0.0199 0.0213
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0032 0.0051 0.0086
Trichomonas vaginalis glucosylceramidase, putative 0.0177 0.0608 0.3543
Echinococcus multilocularis beta LACTamase domain containing family member 0.0412 0.1505 0.1617
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0107 0.0337 0.0571
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0077 0.0223 0.0217
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0073 0.0207 0.0617
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0412 0.1505 0.15
Echinococcus granulosus lipoxygenase domain containing protein 0.004 0.008 0.0136
Schistosoma mansoni hypothetical protein 0.0159 0.0539 0.0912
Mycobacterium ulcerans acyl-CoA synthetase 0.0078 0.0227 0.0671
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.004 0.0083 0.014
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0195 0.0677 0.0671
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0287 0.1027 0.1739
Echinococcus granulosus PHD finger protein rhinoceros 0.0058 0.0152 0.0257
Schistosoma mansoni DNA polymerase eta 0.004 0.0083 0.0141
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0019 0.0001 0.0003
Loa Loa (eye worm) hypothetical protein 0.0073 0.0207 0.0351
Mycobacterium tuberculosis Probable esterase LipL 0.0412 0.1505 0.15
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0087 0.0262 0.0845
Echinococcus granulosus RUN 0.004 0.008 0.0136
Mycobacterium ulcerans acyl-CoA synthetase 0.0078 0.0227 0.0671
Schistosoma mansoni zinc finger protein 0.0034 0.006 0.0102
Brugia malayi AMP-binding enzyme family protein 0.0078 0.0227 0.0676
Schistosoma mansoni acetyl-CoA synthetase 0.0078 0.0227 0.0384
Brugia malayi serine/threonine-protein kinase plk-2 0.01 0.031 0.0923
Trichomonas vaginalis CMGC family protein kinase 0.0111 0.0352 0.2052
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0077 0.0223 0.1483
Mycobacterium ulcerans hypothetical protein 0.0078 0.0227 0.0671
Schistosoma mansoni protein kinase 0.0034 0.0059 0.01
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0056 0.0145 0.0245
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0107 0.0337 0.0362
Onchocerca volvulus 0.0073 0.0207 0.1044
Echinococcus multilocularis ecdysone induced protein 78C 0.0073 0.0207 0.0222
Echinococcus granulosus lipoxygenase domain containing protein 0.004 0.008 0.0136
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0034 0.006 0.0171
Mycobacterium ulcerans acyl-CoA synthetase 0.0078 0.0227 0.0671
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0073 0.0207 0.0617
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0174 0.0594 0.3558
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0149 0.0499 0.0536
Brugia malayi hypothetical protein 0.0034 0.006 0.0179
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0034 0.0059 0.01
Trichomonas vaginalis alpha-glucosidase, putative 0.0057 0.0147 0.0854
Trichomonas vaginalis CAMK family protein kinase 0.01 0.031 0.1806
Schistosoma mansoni FFA transport protein 0.0829 0.3099 0.525
Schistosoma mansoni retinoic acid receptor RXR 0.0073 0.0207 0.0351
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0073 0.0207 0.0351
Loa Loa (eye worm) carboxylesterase 0.007 0.0198 0.0334
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0031 0.0046 0.0077
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0159 0.0538 1
Onchocerca volvulus Protein ultraspiracle homolog 0.0073 0.0207 0.1044
Brugia malayi Bromodomain containing protein 0.0062 0.0166 0.0494
Trichomonas vaginalis CMGC family protein kinase 0.0111 0.0352 0.2052
Onchocerca volvulus 0.0412 0.1505 0.8753
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0028 0.0163
Schistosoma mansoni nuclear receptor nhr-48 0.0034 0.006 0.0102
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0034 0.0059 0.0391
Toxoplasma gondii pyruvate kinase PyKII 0.0034 0.006 0.0399
Schistosoma mansoni hypothetical protein 0.1222 0.4605 0.78
Brugia malayi jmjC domain containing protein 0.0077 0.0224 0.0666
Echinococcus granulosus GTP binding nuclear protein Ran 0.0087 0.0262 0.0443
Brugia malayi steroid hormone receptor 0.0073 0.0207 0.0617
Echinococcus multilocularis importin subunit beta 1 0.0146 0.0489 0.0525
Trypanosoma brucei DNA polymerase eta, putative 0.004 0.0083 0.0551
Trypanosoma cruzi pyruvate kinase 2, putative 0.0067 0.0185 0.0595
Entamoeba histolytica hypothetical protein 0.0026 0.0027 0.0177
Mycobacterium leprae conserved hypothetical protein 0.0412 0.1505 0.4912
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0217 0.076 0.0754
Brugia malayi ecdysteroid receptor 0.0073 0.0207 0.0617
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0083 0.0551
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0073 0.0207 0.0617
Brugia malayi PHD-finger family protein 0.0058 0.0152 0.0452
Echinococcus granulosus neutral alpha glucosidase AB 0.0153 0.0514 0.087
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0056 0.0323
Mycobacterium tuberculosis Conserved protein 0.0412 0.1505 0.15
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0107 0.0337 0.0571
Loa Loa (eye worm) hypothetical protein 0.0073 0.0207 0.0351
Brugia malayi beta-lactamase 0.0412 0.1505 0.4486
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0022 0.0013 0.0042
Loa Loa (eye worm) hypothetical protein 0.0034 0.006 0.0102
Mycobacterium ulcerans acyl-CoA synthetase 0.0078 0.0227 0.0671
Loa Loa (eye worm) CYP4Cod1 0.0019 0.0002 0.0003
Trypanosoma brucei DNA polymerase IV, putative 0.004 0.0083 0.0551
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0245 0.0865 0.1465
Trypanosoma cruzi fatty acid transporter protein-like, putative 0.0829 0.3099 1
Leishmania major glucose transporter, lmgt2 0.0033 0.0056 0.0181
Brugia malayi acetyltransferase, GNAT family protein 0.0149 0.0499 0.1488
Echinococcus granulosus dna polymerase kappa 0.004 0.0083 0.014
Trichomonas vaginalis penicillin-binding protein, putative 0.0412 0.1505 0.8776
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0041 0.0086 0.0277
Schistosoma mansoni RAR-like nuclear receptor 0.0073 0.0207 0.0351
Giardia lamblia NADH oxidase lateral transfer candidate 0.003 0.0043 0.1205
Trichomonas vaginalis alpha-glucosidase, putative 0.0153 0.0514 0.2993
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0019 0.0001 0.0005
Schistosoma mansoni hypothetical protein 0.004 0.008 0.0136
Trichomonas vaginalis alpha-glucosidase, putative 0.0057 0.0147 0.0854
Toxoplasma gondii LsmAD domain-containing protein 0.0051 0.0123 0.0817
Loa Loa (eye worm) oxidoreductase 0.0078 0.0227 0.0384
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0027 0.0031 0.0053
Echinococcus granulosus thioredoxin glutathione reductase 0.0086 0.0259 0.0438
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0034 0.0059 0.0349
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0044 0.0097 0.0641
Trichomonas vaginalis D-aminoacylase, putative 0.0412 0.1505 0.8776
Leishmania major protein kinase, putative 0.0034 0.0059 0.0192
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0028 0.0163
Mycobacterium tuberculosis Conserved protein 0.0412 0.1505 0.15
Onchocerca volvulus 0.004 0.008 0.0291
Echinococcus multilocularis dnaJ subfamily B 0.1222 0.4605 0.4947
Mycobacterium ulcerans beta-lactamase 0.0412 0.1505 0.4483
Schistosoma mansoni alpha glucosidase 0.0153 0.0514 0.087
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0117 0.0376 0.1115
Brugia malayi AMP-binding enzyme family protein 0.0078 0.0227 0.0676
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0077 0.0223 0.072
Onchocerca volvulus 0.0398 0.1453 0.844
Loa Loa (eye worm) hypothetical protein 0.0026 0.0027 0.0045
Trypanosoma brucei unspecified product 0.0028 0.0035 0.0233
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0077 0.0223 0.0378
Trypanosoma brucei DNA polymerase IV, putative 0.004 0.0083 0.0551
Brugia malayi orphan nuclear receptor NR2E1 0.0034 0.006 0.0179
Trypanosoma cruzi fatty acid transporter protein-like, putative 0.0829 0.3099 1
Schistosoma mansoni polycystin 1-related 0.004 0.008 0.0136
Plasmodium falciparum glutathione reductase 0.0086 0.0257 0.1536
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.027 0.0964 0.2871
Onchocerca volvulus 0.004 0.008 0.0291
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0024 0.002 0.0116
Loa Loa (eye worm) hypothetical protein 0.0038 0.0076 0.0128
Trichomonas vaginalis antibiotic synthetase, putative 0.0078 0.0227 0.1322
Loa Loa (eye worm) hypothetical protein 0.0034 0.006 0.0102
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0019 0.0002 0.0011
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0083 0.0551
Trichomonas vaginalis glucosylceramidase, putative 0.027 0.0964 0.5618
Echinococcus multilocularis sodium coupled monocarboxylate transporter 1 0.0115 0.037 0.0397
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.003 0.0043 0.0137
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0073 0.0207 0.0351
Brugia malayi jmjC domain containing protein 0.0019 0.0001 0.0002
Echinococcus granulosus sodium:myo inositol cotransporter 0.0115 0.037 0.0626
Entamoeba histolytica acetyltransferase, GNAT family 0.004 0.0083 0.0549
Trichomonas vaginalis glucosylceramidase, putative 0.0177 0.0608 0.3543
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0078 0.0227 0.0671
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0019 0.0002 0.0011
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.007 0.0198 0.0335
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.0019 0.0002 0.0011
Loa Loa (eye worm) pyruvate kinase 0.0067 0.0185 0.0312
Schistosoma mansoni pyruvate kinase 0.0067 0.0185 0.0313
Echinococcus multilocularis JmjC domain containing protein 4 0.0019 0.0001 0.0001
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0028 0.0163
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0078 0.0227 0.0676
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0073 0.0207 0.0351
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0073 0.0207 0.0617
Brugia malayi Thioredoxin reductase 0.0086 0.0257 0.0765
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0034 0.0059 0.01
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0034 0.006 0.0064
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0026 0.0027 0.0177
Mycobacterium ulcerans acyl-CoA synthetase 0.0078 0.0227 0.0671
Toxoplasma gondii histone lysine methyltransferase SET1 0.0222 0.078 0.5178
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0024 0.002 0.0132
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0159 0.0538 1
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0025 0.0026 0.0028
Trichomonas vaginalis D-aminoacylase, putative 0.0412 0.1505 0.8776
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0055 0.0139 0.0827
Trypanosoma cruzi hexose transporter 0.0033 0.0056 0.0179
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0032 0.0051 0.0054
Echinococcus multilocularis lysine specific demethylase 6a 0.0019 0.0001 0.0001
Trypanosoma brucei PAB1-binding protein , putative 0.0051 0.0123 0.0817
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0032 0.0051 0.0299
Onchocerca volvulus 0.0467 0.1715 1
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0073 0.0207 0.0351
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.004 0.0083 0.0271
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0026 0.0028 0.0163
Loa Loa (eye worm) hypothetical protein 0.01 0.0311 0.0527
Loa Loa (eye worm) hypothetical protein 0.0146 0.0489 0.0827
Trichomonas vaginalis esterase, putative 0.0412 0.1505 0.8776
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0078 0.0227 0.0742
Onchocerca volvulus 0.0114 0.0366 0.1989
Loa Loa (eye worm) hypothetical protein 0.0073 0.0207 0.0351
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0287 0.1027 0.1739
Schistosoma mansoni ap endonuclease 0.0077 0.0223 0.0378
Toxoplasma gondii hypothetical protein 0.0055 0.0139 0.092
Brugia malayi hypothetical protein 0.0412 0.1505 0.4483
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0073 0.0207 0.0222
Giardia lamblia Pyruvate kinase 0.0034 0.006 0.1704
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0038 0.0076 0.0129
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0412 0.1505 0.2549
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0078 0.0227 0.0671
Echinococcus multilocularis lysyl tRNA synthetase 0.0024 0.002 0.0021
Loa Loa (eye worm) glutaminase 0.0303 0.1089 0.1845
Plasmodium falciparum protein kinase 6 0.0454 0.1666 1
Plasmodium falciparum transportin 0.0028 0.0035 0.0204
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0034 0.0059 0.01
Schistosoma mansoni jumonji/arid domain-containing protein 0.0077 0.0224 0.0379
Brugia malayi nuclear receptor NHR-88 0.0073 0.0207 0.0617
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0078 0.0227 0.0671
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.003 0.0043 0.0137
Echinococcus granulosus acetylcholinesterase 0.007 0.0198 0.0334
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.01 0.031 0.0333
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0038 0.0073 0.0123
Trichomonas vaginalis glucosylceramidase, putative 0.0177 0.0608 0.3543
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0032 0.0051 0.0153
Loa Loa (eye worm) hypothetical protein 0.0051 0.0123 0.0208
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0061 0.0163 0.0275
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.1561 0.5903 1
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0083 0.0267
Echinococcus granulosus General substrate transporter 0.0092 0.028 0.0474
Schistosoma mansoni terminal deoxycytidyl transferase 0.004 0.0083 0.0141
Echinococcus multilocularis pyruvate kinase 0.0067 0.0185 0.0198
Echinococcus granulosus translational activator gcn1 0.0028 0.0035 0.0059
Brugia malayi Sugar transporter family protein 0.0107 0.0337 0.1004
Brugia malayi nuclear hormone receptor 0.0073 0.0207 0.0617
Trypanosoma cruzi DNA polymerase eta, putative 0.004 0.0083 0.0267
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0026 0.0027 0.0086
Leishmania major trypanothione reductase 0.0086 0.0257 0.0839
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0034 0.0059 0.0391
Schistosoma mansoni jumonji domain containing protein 0.0019 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0034 0.006 0.0102
Loa Loa (eye worm) pyruvate kinase 0.0067 0.0185 0.0312
Echinococcus granulosus importin 5 0.0028 0.0035 0.0059
Trichomonas vaginalis CAMK family protein kinase 0.0034 0.0059 0.0343
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0057 0.0147 0.0473
Schistosoma mansoni lipoxygenase 0.0111 0.0353 0.0597
Echinococcus multilocularis dna polymerase kappa 0.004 0.0083 0.0089
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.003 0.0043 0.0434
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0061 0.0163 0.0174
Brugia malayi nuclear hormone receptor family member odr-7 0.0034 0.006 0.0179
Schistosoma mansoni serine/threonine protein kinase 0.0111 0.0352 0.0597
Schistosoma mansoni thyroid hormone receptor 0.0073 0.0207 0.0351
Echinococcus granulosus solute carrier family 5 0.0115 0.037 0.0626
Mycobacterium ulcerans acyl-CoA synthetase 0.0078 0.0227 0.0671
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0078 0.0227 0.0732
Onchocerca volvulus 0.0078 0.0227 0.1162
Brugia malayi AMP-binding enzyme family protein 0.0078 0.0227 0.0676
Echinococcus granulosus ecdysone induced protein 78C 0.0073 0.0207 0.0351
Leishmania major DNA polymerase eta, putative 0.004 0.0083 0.0271
Giardia lamblia Kinase, PLK 0.01 0.031 0.8797
Loa Loa (eye worm) hypothetical protein 0.0038 0.0076 0.0128
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0292 0.1045 0.6944
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0083 0.0267
Loa Loa (eye worm) cytochrome P450 family protein 0.0019 0.0002 0.0003
Trypanosoma brucei THT1 - hexose transporter, putative 0.0033 0.0056 0.0368
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0032 0.0051 0.0087
Echinococcus multilocularis sodium:glucose cotransporter 2 0.0115 0.037 0.0397
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.003 0.0043 0.025
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0024 0.002 0.0054
Brugia malayi Doublecortin family protein 0.004 0.008 0.0239
Loa Loa (eye worm) hypothetical protein 0.0061 0.0163 0.0275
Schistosoma mansoni hypothetical protein 0.0159 0.0539 0.0912
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0078 0.0227 0.0671
Trichomonas vaginalis helicase, putative 0.0026 0.0028 0.0163
Toxoplasma gondii HEAT repeat-containing protein 0.0028 0.0035 0.023
Onchocerca volvulus 0.0034 0.006 0.0171
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0217 0.076 0.0754
Loa Loa (eye worm) cytochrome P450 family protein 0.0019 0.0002 0.0003
Leishmania major acetoin dehydrogenase e3 component-like protein 0.003 0.0043 0.0139
Echinococcus granulosus jumonji domain containing 1A 0.0019 0.0001 0.0001
Echinococcus granulosus lysosomal alpha glucosidase 0.0689 0.2563 0.4342
Plasmodium vivax lysine--tRNA ligase, putative 0.0024 0.002 0.0115
Leishmania major dihydrolipoamide dehydrogenase, putative 0.003 0.0043 0.0139
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.003 0.0043 0.0121
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0073 0.0207 0.0222
Leishmania major hypothetical protein, conserved 0.0412 0.1505 0.4923
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0087 0.0262 0.1739
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0195 0.0677 0.0671
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0117 0.0376 0.112
Trichomonas vaginalis CAMK family protein kinase 0.01 0.031 0.1806
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0078 0.0227 0.0723
Leishmania major acetyl-CoA synthetase, putative 0.0078 0.0227 0.0742
Plasmodium vivax ataxin-2 like protein, putative 0.0051 0.0123 0.0734
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0055 0.0139 0.0827
Brugia malayi ecdysone receptor 0.0034 0.006 0.0179
Plasmodium falciparum lysine--tRNA ligase 0.0024 0.002 0.0115
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0073 0.0207 0.0351
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0073 0.0207 0.0351
Echinococcus multilocularis snurportin 1 0.1561 0.5903 0.6342
Toxoplasma gondii PHD-finger domain-containing protein 0.0058 0.0152 0.1008
Echinococcus multilocularis neuropeptide receptor A26 0.0502 0.1851 0.1988
Echinococcus granulosus sodium:glucose cotransporter 0.0115 0.037 0.0626
Leishmania major mitochondrial DNA polymerase beta 0.0292 0.1045 0.3418
Schistosoma mansoni peptidase Clp (S14 family) 0.0159 0.0538 0.0911
Echinococcus multilocularis long chain fatty acid transport protein 4 0.0829 0.3099 0.3329
Trichomonas vaginalis antibiotic synthetase, putative 0.0078 0.0227 0.1322
Schistosoma mansoni pyruvate kinase 0.0034 0.006 0.0102
Brugia malayi lysyl-tRNA synthetase 0.0024 0.002 0.0059
Brugia malayi Cytochrome P450 family protein 0.0019 0.0002 0.0005
Trypanosoma brucei glucosidase, putative 0.0153 0.0514 0.3411
Trichomonas vaginalis alpha-glucosidase, putative 0.0057 0.0147 0.0854
Echinococcus multilocularis pyruvate kinase 0.0034 0.006 0.0064
Loa Loa (eye worm) hypothetical protein 0.0067 0.0185 0.0312
Loa Loa (eye worm) hypothetical protein 0.0034 0.006 0.0102
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0412 0.1505 0.255
Loa Loa (eye worm) hypothetical protein 0.004 0.008 0.0136
Brugia malayi jmjC domain containing protein 0.0019 0.0001 0.0002
Toxoplasma gondii FATC domain-containing protein 0.0026 0.0027 0.0177
Brugia malayi AMP-binding enzyme family protein 0.0078 0.0227 0.0676
Trichomonas vaginalis glucosylceramidase, putative 0.0177 0.0608 0.3543
Trichomonas vaginalis CMGC family protein kinase 0.0111 0.0352 0.2052
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.004 0.0083 0.0141
Schistosoma mansoni hypothetical protein 0.0159 0.0539 0.0912
Toxoplasma gondii ABC1 family protein 0.0412 0.1505 1
Mycobacterium ulcerans esterase/lipase LipP 0.0412 0.1505 0.4483
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0057 0.0147 0.0974
Brugia malayi conserved hypotetical protein 0.0034 0.006 0.0179
Toxoplasma gondii facilitative glucose transporter GT1 0.0107 0.0337 0.2239
Echinococcus multilocularis mitogen activated protein kinase 3 0.0111 0.0352 0.0378
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0061 0.0163 0.0275
Echinococcus multilocularis GPCR, family 2 0.0159 0.0539 0.0578
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0034 0.006 0.0102
Trichomonas vaginalis glucosylceramidase, putative 0.027 0.0964 0.5618
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0032 0.0051 0.0054
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0037 0.0072 0.0234
Loa Loa (eye worm) hypothetical protein 0.0026 0.0029 0.0048
Loa Loa (eye worm) thioredoxin reductase 0.0086 0.0257 0.0435
Echinococcus granulosus thyroid hormone receptor alpha 0.0034 0.006 0.0102
Trypanosoma cruzi PAB1-binding protein , putative 0.0051 0.0123 0.0397
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0159 0.0538 0.0577
Loa Loa (eye worm) hypothetical protein 0.0034 0.006 0.0102
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0287 0.1027 0.1739
Brugia malayi Calcitonin receptor-like protein seb-1 0.0503 0.1855 0.5529
Mycobacterium ulcerans flavoprotein disulfide reductase 0.003 0.0043 0.0121
Toxoplasma gondii thioredoxin reductase 0.0086 0.0257 0.1705
Trypanosoma brucei THT1 - hexose transporter, putative 0.0033 0.0056 0.0368
Echinococcus granulosus pyruvate kinase 0.0034 0.006 0.0102
Plasmodium falciparum phd finger protein, putative 0.0058 0.0152 0.0906
Loa Loa (eye worm) nuclear receptor NHR-67 0.0034 0.006 0.0102
Loa Loa (eye worm) isocitrate dehydrogenase 0.0032 0.0051 0.0086
Schistosoma mansoni protein phosphatase 2C 0.0019 0.0001 0.0002
Brugia malayi AMP-binding enzyme family protein 0.0078 0.0227 0.0676
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0052 0.0129 0.0383
Entamoeba histolytica hypothetical protein 0.0024 0.002 0.0133
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0111 0.0352 0.1136
Loa Loa (eye worm) hypothetical protein 0.0034 0.006 0.0102
Schistosoma mansoni protein kinase 0.0034 0.0059 0.01
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0412 0.1505 0.4486
Schistosoma mansoni kinase 0.0052 0.0128 0.0217
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0031 0.0046 0.0049
Trichomonas vaginalis alpha-glucosidase, putative 0.0153 0.0514 0.2993
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0287 0.1027 0.3059
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0028 0.0163
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0159 0.0538 1
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0087 0.0262 0.0443
Echinococcus granulosus serine:threonine protein kinase PLK1 0.01 0.031 0.0525
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0077 0.0223 0.1336
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.003 0.0043 0.025
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0087 0.0262 0.0845
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.003 0.0043 0.0072
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0034 0.006 0.0102
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0083 0.0551
Onchocerca volvulus Bile acid receptor homolog 0.0073 0.0207 0.1044
Plasmodium vivax multidomain scavenger receptor, putative 0.004 0.008 0.0477
Brugia malayi Steroid receptor seven-up type 2 0.0073 0.0207 0.0617
Echinococcus multilocularis nuclear receptor nhr 48 0.0034 0.006 0.0064
Trichomonas vaginalis conserved hypothetical protein 0.0107 0.0337 0.1965
Loa Loa (eye worm) jmjC domain-containing protein 0.0019 0.0001 0.0001
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0111 0.0353 0.0597
Trypanosoma brucei pyruvate kinase 1 0.0067 0.0185 0.1225
Brugia malayi Probable ClpP-like protease 0.0159 0.0538 0.1602
Loa Loa (eye worm) hypothetical protein 0.0047 0.0107 0.0181
Loa Loa (eye worm) sugar transporter 0.0107 0.0337 0.0571
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0159 0.0539 0.0912
Trichomonas vaginalis glucosylceramidase, putative 0.0177 0.0608 0.3543
Plasmodium vivax pyruvate kinase, putative 0.0067 0.0185 0.1102
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0292 0.1045 0.3373
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0111 0.0352 0.1136
Plasmodium vivax proline--tRNA ligase, putative 0.0037 0.0072 0.0425
Echinococcus granulosus peregrin 0.0062 0.0166 0.0281
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0245 0.0868 0.147
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0412 0.1505 0.255
Plasmodium falciparum thioredoxin reductase 0.0086 0.0257 0.1536
Trichomonas vaginalis glucosylceramidase, putative 0.027 0.0964 0.5618
Mycobacterium tuberculosis Conserved hypothetical protein 0.004 0.0083 0.0077
Schistosoma mansoni hypothetical protein 0.1428 0.5392 0.9134
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0149 0.0499 0.0846
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0217 0.076 0.247
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0083 0.0551
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0107 0.0337 0.0571
Schistosoma mansoni hypothetical protein 0.1428 0.5392 0.9134
Plasmodium vivax glutathione reductase, putative 0.0086 0.0257 0.1536
Toxoplasma gondii pyruvate kinase PyK1 0.0067 0.0185 0.1225
Schistosoma mansoni glucose transport protein 0.0107 0.0337 0.0571
Brugia malayi Pre-SET motif family protein 0.0061 0.0163 0.0484
Toxoplasma gondii HEAT repeat-containing protein 0.0146 0.0489 0.3245
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0087 0.0262 0.1567
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0119 0.0383 0.2231
Brugia malayi nuclear receptor RXR 0.0038 0.0076 0.0226
Schistosoma mansoni pyruvate kinase 0.0067 0.0185 0.0313
Echinococcus multilocularis isocitrate dehydrogenase 0.0032 0.0051 0.0054
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.003 0.0043 0.0137
Echinococcus multilocularis thioredoxin glutathione reductase 0.0086 0.0259 0.0278
Brugia malayi Cytochrome P450 family protein 0.0048 0.0113 0.0335
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0138 0.0457 0.3037
Trypanosoma brucei glucose transporter, putative 0.0033 0.0056 0.0368
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0034 0.006 0.0102
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0055 0.0139 0.0434
Trichomonas vaginalis ran, putative 0.0087 0.0262 0.1526
Loa Loa (eye worm) hypothetical protein 0.0078 0.0227 0.0384
Trypanosoma brucei hypothetical protein, conserved 0.0412 0.1505 1
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0025 0.0026 0.0044
Leishmania major glucose transporter, lmgt1 0.0033 0.0056 0.0181
Toxoplasma gondii protein kinase, putative 0.0303 0.1087 0.7221
Brugia malayi Nuclear hormone receptor E75 0.0034 0.006 0.0179
Brugia malayi glutaminase DH11.1 0.0303 0.1089 0.3246
Loa Loa (eye worm) hypothetical protein 0.0115 0.037 0.0626
Brugia malayi isocitrate dehydrogenase 0.0032 0.0051 0.015
Leishmania major cytochrome p450-like protein 0.0019 0.0002 0.0006
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0078 0.0227 0.0723
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0153 0.0514 0.3411
Brugia malayi Latrophilin receptor protein 2 0.0159 0.0539 0.1604
Schistosoma mansoni rab6-interacting 0.004 0.008 0.0136
Loa Loa (eye worm) hypothetical protein 0.0019 0.0001 0.0001
Brugia malayi nuclear receptor RXR 0.0034 0.006 0.0179
Leishmania major fatty acid transporter protein-like protein 0.0818 0.3058 1
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0034 0.0059 0.0063
Echinococcus multilocularis high affinity choline transporter 1 0.0115 0.037 0.0397
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0028 0.0163
Schistosoma mansoni sodium/solute symporter 0.0115 0.037 0.0626
Trypanosoma cruzi polo-like protein kinase, putative 0.01 0.031 0.0999
Leishmania major glucose transporter, lmgt3 0.0033 0.0056 0.0181
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0073 0.0207 0.0351
Echinococcus multilocularis lamin 0.0027 0.0031 0.0033
Schistosoma mansoni importin-beta 2 0.0028 0.0035 0.0059
Schistosoma mansoni lipoxygenase 0.004 0.008 0.0136
Brugia malayi hypothetical protein 0.0051 0.0123 0.0366
Loa Loa (eye worm) hypothetical protein 0.0057 0.0147 0.0248
Schistosoma mansoni phosphatidylserine receptor 0.0019 0.0001 0.0002
Leishmania major importin beta-1 subunit, putative 0.0119 0.0383 0.1251
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0077 0.0223 0.1336
Echinococcus multilocularis phd:f box containing protein 0.0019 0.0001 0.0001
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0104 0.0328 0.0322
Loa Loa (eye worm) hypothetical protein 0.0027 0.0031 0.0053
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0034 0.0059 0.0349
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0058 0.0152 0.0257
Onchocerca volvulus 0.0078 0.0227 0.1162
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0024 0.002 0.0054
Echinococcus granulosus pyruvate kinase 0.0034 0.006 0.0102
Mycobacterium tuberculosis Probable oxidoreductase 0.0217 0.076 0.0754
Trypanosoma brucei importin beta-1 subunit, putative 0.0146 0.0489 0.3245
Echinococcus granulosus FTZ F1 alpha 0.0073 0.0207 0.0351
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0174 0.0594 0.3942
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0078 0.0227 0.0732
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0057 0.0147 0.0473
Toxoplasma gondii NADPH-glutathione reductase 0.003 0.0043 0.0282
Echinococcus multilocularis carboxylesterase 5A 0.007 0.0198 0.0212
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0077 0.0223 0.6341
Schistosoma mansoni hypothetical protein 0.1561 0.5903 1
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0111 0.0352 0.2339
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0037 0.0072 0.0476
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0022 0.0012 0.0037
Trypanosoma brucei THT1 - hexose transporter, putative 0.0033 0.0056 0.0368
Brugia malayi nuclear receptor NHR-88 0.0034 0.006 0.0179
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0078 0.0227 0.0221
Loa Loa (eye worm) intermediate filament protein 0.0027 0.0031 0.0053
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0104 0.0328 0.0322
Loa Loa (eye worm) hypothetical protein 0.0032 0.0051 0.0087
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0037 0.0072 0.0234
Loa Loa (eye worm) hypothetical protein 0.0058 0.0152 0.0257
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0287 0.1027 0.1103
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0073 0.0207 0.0222
Echinococcus granulosus long chain fatty acid transport protein 4 0.0829 0.3099 0.525
Trichomonas vaginalis alpha-glucosidase, putative 0.0057 0.0147 0.0854
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0411 0.15 0.254
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0041 0.0086 0.0277
Chlamydia trachomatis pyruvate kinase 0.0067 0.0185 0.3177
Trichomonas vaginalis set domain proteins, putative 0.0467 0.1715 1
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0159 0.0538 0.091
Brugia malayi Nuclear hormone receptor-like 1 0.0038 0.0076 0.0226
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0073 0.0207 0.0351
Trichomonas vaginalis alpha-glucosidase, putative 0.0153 0.0514 0.2993
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0032 0.0051 0.0148
Echinococcus granulosus transportin 1 0.0028 0.0035 0.0059
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0077 0.0223 0.1484
Mycobacterium ulcerans acyl-CoA synthetase 0.0078 0.0227 0.0671
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0287 0.1027 0.1739
Loa Loa (eye worm) hypothetical protein 0.0038 0.0076 0.0128
Toxoplasma gondii propionate-CoA ligase 0.0078 0.0227 0.1507
Echinococcus granulosus lamin 0.0027 0.0031 0.0053
Trichomonas vaginalis ap endonuclease, putative 0.0077 0.0223 0.1301
Loa Loa (eye worm) DR-78 0.0034 0.006 0.0102
Echinococcus multilocularis acetylcholinesterase 0.007 0.0198 0.0212
Echinococcus multilocularis lamin dm0 0.0027 0.0031 0.0033
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0087 0.0262 0.1739
Brugia malayi Glycosyl hydrolases family 31 protein 0.0057 0.0147 0.0437
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.003 0.0043 0.025
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0032 0.0051 0.0054
Onchocerca volvulus Alhambra homolog 0.0058 0.0152 0.0716
Trichomonas vaginalis maltase-glucoamylase, putative 0.0153 0.0514 0.2993
Toxoplasma gondii transporter, solute:sodium symporter (SSS) family protein 0.0115 0.037 0.2455
Loa Loa (eye worm) hypothetical protein 0.0073 0.0207 0.0351
Loa Loa (eye worm) nuclear hormone receptor 0.0034 0.006 0.0102
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0024 0.002 0.0045
Loa Loa (eye worm) hypothetical protein 0.0034 0.006 0.0102
Leishmania major 4-coumarate:coa ligase-like protein 0.0078 0.0227 0.0742
Entamoeba histolytica serine/threonine protein kinase, putative 0.01 0.031 0.2058
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0028 0.0163
Brugia malayi AMP-binding enzyme family protein 0.0078 0.0227 0.0676
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0028 0.0163
Onchocerca volvulus Pyruvate kinase homolog 0.0067 0.0185 0.091
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0107 0.0337 0.0362
Trypanosoma brucei polo-like protein kinase 0.01 0.031 0.2057
Loa Loa (eye worm) hypothetical protein 0.0073 0.0207 0.0351
Echinococcus granulosus acetylcholinesterase 0.007 0.0198 0.0334
Echinococcus granulosus pyruvate kinase 0.0067 0.0185 0.0312
Loa Loa (eye worm) hypothetical protein 0.0503 0.1855 0.3143
Loa Loa (eye worm) jmjC domain-containing protein 0.0019 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.004 0.008 0.0136
Plasmodium falciparum LCCL domain-containing protein 0.004 0.008 0.0477
Trypanosoma brucei DNA polymerase kappa, putative 0.0028 0.0035 0.0233
Trichomonas vaginalis maltase-glucoamylase, putative 0.0057 0.0147 0.0854
Schistosoma mansoni lysyl-tRNA synthetase 0.0024 0.002 0.0034
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0083 0.0267
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0078 0.0227 0.0221
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.004 0.0083 0.014
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0159 0.0539 0.0578
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0044 0.0097 0.0563
Brugia malayi PHD-finger family protein 0.0026 0.0027 0.0079
Echinococcus multilocularis cpg binding protein 0.0121 0.0391 0.042
Brugia malayi Pyruvate kinase, alpha/beta domain containing protein 0.002 0.0006 0.0018
Trichomonas vaginalis glutaminase, putative 0.0303 0.1089 0.6351
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0056 0.0323
Schistosoma mansoni nuclear receptor 0.0034 0.006 0.0102
Echinococcus multilocularis peregrin 0.0062 0.0166 0.0178
Trypanosoma cruzi PAB1-binding protein , putative 0.0051 0.0123 0.0397
Loa Loa (eye worm) hypothetical protein 0.0073 0.0207 0.0351
Echinococcus multilocularis translational activator gcn1 0.0028 0.0035 0.0037
Echinococcus multilocularis Polycystic kidney disease protein 0.004 0.008 0.0086
Trypanosoma cruzi importin beta-1 subunit, putative 0.0119 0.0383 0.1235
Echinococcus granulosus high affinity choline transporter 1 0.0115 0.037 0.0626
Entamoeba histolytica deoxycytidyl transferase, putative 0.004 0.0083 0.0551
Mycobacterium tuberculosis Conserved protein 0.0412 0.1505 0.15
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.003 0.0043 0.0137
Trypanosoma brucei protein kinase, putative 0.0111 0.0352 0.2339
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0078 0.0227 0.0221
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0032 0.0051 0.0054
Mycobacterium ulcerans acetyl-CoA synthetase 0.0078 0.0227 0.0671
Loa Loa (eye worm) hypothetical protein 0.0078 0.0227 0.0384
Echinococcus multilocularis mitogen activated protein kinase 0.0111 0.0352 0.0378
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.005 0.012 0.0388
Echinococcus multilocularis neutral alpha glucosidase AB 0.0153 0.0514 0.0552
Schistosoma mansoni lysyl-tRNA synthetase 0.0024 0.002 0.0034
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0028 0.0163
Plasmodium falciparum mitogen-activated protein kinase 2 0.0174 0.0594 0.3558
Plasmodium vivax hexose transporter 0.0107 0.0337 0.2019
Leishmania major DNA polymerase kappa, putative 0.004 0.0083 0.0271
Echinococcus granulosus nuclear receptor nhr 48 0.0034 0.006 0.0102
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0073 0.0207 0.0617
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0159 0.0538 0.3223
Brugia malayi glutathione reductase 0.0086 0.0257 0.0765
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0044 0.0097 0.0575
Brugia malayi follicle stimulating hormone receptor 0.0245 0.0868 0.2586
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0073 0.0207 0.0617
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0087 0.0262 0.0281
Onchocerca volvulus Serine\/threonine kinase homolog 0.01 0.031 0.1654
Schistosoma mansoni coup transcription factor 0.0073 0.0207 0.0351
Echinococcus multilocularis FTZ F1 alpha 0.0073 0.0207 0.0222
Trichomonas vaginalis mercuric reductase, putative 0.003 0.0043 0.0247
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0057 0.0147 0.0685
Loa Loa (eye worm) hypothetical protein 0.0073 0.0207 0.0351
Schistosoma mansoni hypothetical protein 0.0412 0.1505 0.2549
Loa Loa (eye worm) hypothetical protein 0.0034 0.006 0.0102
Echinococcus granulosus dnaJ subfamily B 0.1222 0.4605 0.78
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0027 0.0155
Schistosoma mansoni high-affinity choline transporter 0.0115 0.037 0.0626
Trichomonas vaginalis pyruvate kinase, putative 0.0067 0.0185 0.1075
Trypanosoma brucei DNA polymerase IV, putative 0.004 0.0083 0.0551
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0034 0.006 0.0179
Trypanosoma brucei glucose transporter 1E 0.0033 0.0056 0.0368
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD6 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0818 0.3058 0.3053
Schistosoma mansoni glucose transport protein 0.0107 0.0337 0.0571
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0153 0.0514 0.3412
Echinococcus multilocularis musashi 0.0027 0.0031 0.0033
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0078 0.0227 0.0723
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0019 0.0001 0.0003
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0689 0.2563 0.4342
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0412 0.1505 0.15
Mycobacterium tuberculosis Probable hydrolase 0.0412 0.1505 0.15
Leishmania major pantothenate kinase subunit, putative 0.0026 0.003 0.0097
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0073 0.0207 0.0351
Echinococcus multilocularis serine protein kinase ATM 0.0026 0.0027 0.0029
Trypanosoma brucei unspecified product 0.0028 0.0035 0.0233
Giardia lamblia Prolyl-tRNA synthetase 0.0032 0.0051 0.1457
Toxoplasma gondii PHD-finger domain-containing protein 0.0058 0.0152 0.1008
Loa Loa (eye worm) histone methyltransferase 0.0038 0.0073 0.0123
Trichomonas vaginalis CAMK family protein kinase 0.01 0.031 0.1806
Giardia lamblia DINP protein human, muc B family 0.004 0.0083 0.2354
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0023 0.0016 0.0017
Loa Loa (eye worm) hypothetical protein 0.0115 0.037 0.0626
Trichomonas vaginalis pyruvate kinase, putative 0.0067 0.0185 0.1075
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0073 0.0207 0.0351
Leishmania major hypothetical protein, conserved 0.0051 0.0123 0.0402
Schistosoma mansoni glutaminase 0.0303 0.1089 0.1846
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0111 0.0352 0.1151
Loa Loa (eye worm) hypothetical protein 0.0034 0.0059 0.01
Entamoeba histolytica acyl-coA synthetase, putative 0.0078 0.0227 0.1507
Brugia malayi hypothetical protein 0.004 0.008 0.0239
Trichomonas vaginalis CAMK family protein kinase 0.01 0.031 0.1806
Schistosoma mansoni inositol transporter 0.0115 0.037 0.0626
Schistosoma mansoni jumonji/arid domain-containing protein 0.0077 0.0224 0.0379
Onchocerca volvulus Pyruvate kinase homolog 0.0067 0.0185 0.091
Echinococcus multilocularis transportin 1 0.0028 0.0035 0.0037
Loa Loa (eye worm) hypothetical protein 0.0078 0.0227 0.0384
Leishmania major hypothetical protein, conserved 0.0019 0.0001 0.0003
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.003 0.0043 0.0036
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0077 0.0223 0.073
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0028 0.0163
Giardia lamblia Kinase, CMGC MAPK 0.0111 0.0352 1
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0073 0.0207 0.0222
Leishmania major GTP-binding protein, putative 0.0087 0.0262 0.0856
Loa Loa (eye worm) hypothetical protein 0.007 0.0198 0.0334
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0019 0.0001 0.0002
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.004 0.0083 0.0483
Echinococcus granulosus histone acetyltransferase KAT2B 0.0145 0.0483 0.0818
Trichomonas vaginalis CAMK family protein kinase 0.01 0.031 0.1806
Loa Loa (eye worm) hypothetical protein 0.0022 0.0013 0.0022
Echinococcus multilocularis sodium:myo inositol cotransporter 0.0115 0.037 0.0397
Trypanosoma brucei glucose transporter 2A 0.0033 0.0056 0.0368
Echinococcus multilocularis thyroid hormone receptor alpha 0.0073 0.0207 0.0222
Echinococcus granulosus jumonji domain containing protein 0.0081 0.0239 0.0405
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0107 0.0337 0.0571
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0117 0.0376 0.0637
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0073 0.0207 0.0222
Schistosoma mansoni hypothetical protein 0.0052 0.0129 0.0218
Trypanosoma brucei Importin-beta N-terminal domain/HEAT-like repeat, putative 0.0028 0.0035 0.023
Onchocerca volvulus 0.0052 0.0129 0.0579
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0083 0.0551
Echinococcus granulosus intermediate filament protein 0.0027 0.0031 0.0053
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0073 0.0207 0.0351
Brugia malayi Cytochrome P450 family protein 0.0019 0.0002 0.0005
Trichomonas vaginalis CAMK family protein kinase 0.0051 0.0123 0.0718
Brugia malayi kap beta 3 protein 0.0028 0.0035 0.0103
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0028 0.0163
Loa Loa (eye worm) jmjC domain-containing protein 0.0019 0.0001 0.0001
Plasmodium falciparum pyruvate kinase 0.0067 0.0185 0.1102
Schistosoma mansoni hypothetical protein 0.0058 0.0152 0.0257
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0111 0.0353 0.0379
Trypanosoma brucei glucose transporter, putative 0.0033 0.0056 0.0368
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0191 0.0659 0.0708
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0159 0.0539 0.0912
Echinococcus multilocularis RUN 0.004 0.008 0.0086

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.