TDR Targets

Basic information

Technical information

TDR Targets ID: 731166
Name: 5-(3-methoxyphenyl)-N-(5-methyl-2-phenylpyraz ol-3-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]py rimidine-2-carboxamide
MW: 492.453 | Formula: C25H19F3N6O2
H donors: 1 H acceptors: 4 LogP: 4.75 Rotable bonds: 7
Rule of 5 violations (Lipinski): 1
SMILES: COc1cccc(c1)c1nc2cc(nn2c(c1)C(F)(F)F)C(=O)Nc1cc(nn1c1ccccc1)C
InChi: 1S/C25H19F3N6O2/c1-15-11-22(33(31-15)17-8-4-3-5-9-17)30-24(35)20-14-23-29-19(16-7-6-10-18(12-16)36-2)13-21(25(26,27)28)34(23)32-20/h3-14H,1-2H3,(H,30,35)
InChiKey: XMIYYCZLVMIGBC-UHFFFAOYSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

5-(3-methoxyphenyl)-N-(5-methyl-2-phenyl-pyrazol-3-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide
5-(3-methoxyphenyl)-N-(5-methyl-2-phenyl-3-pyrazolyl)-7-(trifluoromethyl)-2-pyrazolo[1,5-a]pyrimidinecarboxamide
CBKinase1_011600
ZINC02879542
CBKinase1_024000

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Echinococcus multilocularis	methyl CpG binding domain protein 2	0.0015	0.0005	0.0001
Echinococcus granulosus	histone lysine methyltransferase setb	0.0078	0.0315	0.0311
Loa Loa (eye worm)	hypothetical protein	0.0015	0.0008	0.0018
Echinococcus multilocularis	cpg binding protein	0.0066	0.0257	0.0254
Echinococcus granulosus	nibrin	0.0015	0.0006	0.0002
Brugia malayi	MH2 domain containing protein	0.0025	0.0056	0.0135
Giardia lamblia	Endonuclease/Exonuclease/phosphatase	0.0019	0.0024	1
Trichomonas vaginalis	D-aminoacylase, putative	0.0039	0.0122	0.0299
Echinococcus multilocularis	cadherin EGF LAG seven pass G type receptor	0.0046	0.0159	0.0155
Loa Loa (eye worm)	intermediate filament tail domain-containing protein	0.0027	0.0063	0.0154
Trypanosoma cruzi	cytochrome P450, putative	0.0025	0.0054	0.0347
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-41	0.0032	0.0092	0.0225
Trypanosoma cruzi	Plus-3 domain/Zinc finger, C3HC4 type (RING finger), putative	0.0015	0.0007	0.0011
Loa Loa (eye worm)	hypothetical protein	0.0032	0.0092	0.0225
Loa Loa (eye worm)	hypothetical protein	0.0079	0.0319	0.0781
Schistosoma mansoni	nuclear hormone receptor	0.0015	0.0008	0.0006
Trypanosoma cruzi	UEV domain/Zinc finger, C3HC4 type (RING finger), putative	0.0015	0.0007	0.0011
Giardia lamblia	Zinc finger domain	0.0015	0.0007	0.0832
Loa Loa (eye worm)	hypothetical protein	0.0064	0.0247	0.0602
Giardia lamblia	Protein 21.1	0.0015	0.0007	0.0832
Echinococcus multilocularis	Basic leucine zipper (bZIP) transcription	0.0036	0.011	0.0107
Echinococcus granulosus	Zinc finger RanBP2 type	0.03	0.141	0.1406
Echinococcus multilocularis	protein dispatched 1	0.0073	0.0293	0.0289
Mycobacterium leprae	PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE)	0.0036	0.0109	0.8901
Brugia malayi	DKFZp564C0469 protein	0.0015	0.0006	0.0013
Echinococcus multilocularis	nibrin	0.0015	0.0006	0.0002
Schistosoma mansoni	topbp1	0.0015	0.0006	0.0003
Schistosoma mansoni	cpg binding protein	0.0066	0.0257	0.0362
Schistosoma mansoni	hepatocyte nuclear factor 4-alpha (hnf-4-alpha)	0.0015	0.0008	0.0006
Loa Loa (eye worm)	hypothetical protein	0.0039	0.0122	0.0298
Echinococcus granulosus	cell growth regulator with ring finger domain	0.0015	0.0007	0.0004
Echinococcus multilocularis	microtubule associated protein 2	0.1433	0.7	0.6998
Echinococcus granulosus	E3 ubiquitin protein ligase LRSAM1	0.0015	0.0007	0.0004
Echinococcus granulosus	voltage gated potassium channel	0.0021	0.0037	0.0033
Mycobacterium tuberculosis	Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase)	0.0025	0.0057	0.037
Echinococcus granulosus	ecdysone induced protein 78C	0.0032	0.0092	0.0089
Trichomonas vaginalis	hypothetical protein	0.0015	0.0007	0.0018
Echinococcus multilocularis	expressed conserved protein	0.014	0.0624	0.0621
Giardia lamblia	Protein 21.1	0.0015	0.0007	0.0832
Loa Loa (eye worm)	hypothetical protein	0.0015	0.0008	0.0018
Schistosoma mansoni	thyroid hormone receptor	0.0032	0.0092	0.0127
Onchocerca volvulus		0.0039	0.0122	0.0286
Onchocerca volvulus		0.0015	0.0007	0.0004
Loa Loa (eye worm)	hypothetical protein	0.0027	0.0065	0.0157
Schistosoma mansoni	hypothetical protein	0.0866	0.4204	0.6004
Trichomonas vaginalis	ankyrin, putative	0.0015	0.0007	0.0018
Trichomonas vaginalis	conserved hypothetical protein	0.0015	0.0007	0.0018
Trichomonas vaginalis	voltage and ligand gated potassium channel, putative	0.0015	0.0004	0.0009
Schistosoma mansoni	voltage-gated potassium channel	0.008	0.0328	0.0463
Trypanosoma brucei	mitochondrial RNA binding complex 1 subunit	0.03	0.141	1
Loa Loa (eye worm)	cytoplasmic intermediate filament protein	0.0014	0.0002	0.0005
Trypanosoma cruzi	hypothetical protein, conserved	0.0015	0.0007	0.0011
Brugia malayi	Cytochrome P450 family protein	0.0025	0.0054	0.0132
Trichomonas vaginalis	conserved hypothetical protein	0.0015	0.0007	0.0018
Brugia malayi	conserved hypotetical protein	0.0015	0.0008	0.0018
Giardia lamblia	Protein 21.1	0.0015	0.0007	0.0832
Echinococcus granulosus	cpg binding protein	0.0066	0.0257	0.0254
Trichomonas vaginalis	glucosylceramidase, putative	0.0141	0.0628	0.1537
Loa Loa (eye worm)	hypothetical protein	0.0017	0.0017	0.004
Giardia lamblia	Zinc finger domain	0.0015	0.0007	0.0832
Trichomonas vaginalis	conserved hypothetical protein	0.0015	0.0007	0.0018
Plasmodium falciparum	RING zinc finger protein, putative	0.0015	0.0007	0.0004
Trichomonas vaginalis	conserved hypothetical protein	0.0015	0.0006	0.0014
Trypanosoma cruzi	hypothetical protein, conserved	0.03	0.141	1
Leishmania major	hypothetical protein, conserved	0.03	0.141	1
Schistosoma mansoni	lamin	0.0027	0.0063	0.0085
Trypanosoma cruzi	isocitrate dehydrogenase [NADP], mitochondrial precursor, putative	0.0017	0.0016	0.007
Trichomonas vaginalis	conserved hypothetical protein	0.0015	0.0006	0.0014
Echinococcus granulosus	DNA apurinic or apyrimidinic site lyase	0.0019	0.0024	0.002
Trypanosoma cruzi	Zinc finger, C3HC4 type (RING finger), putative	0.0015	0.0007	0.0011
Echinococcus multilocularis	neuropeptide receptor A26	0.0496	0.2376	0.2373
Trypanosoma cruzi	hypothetical protein, conserved	0.03	0.141	1
Entamoeba histolytica	zinc finger domain containing protein	0.0015	0.0007	0.0023
Onchocerca volvulus		0.0039	0.0122	0.0286
Giardia lamblia	Kinase, NEK	0.0015	0.0007	0.0832
Echinococcus granulosus	RING finger and transmembrane domain containing protein	0.0015	0.0007	0.0004
Trypanosoma cruzi	Plus-3 domain/Zinc finger, C3HC4 type (RING finger), putative	0.0015	0.0007	0.0011
Schistosoma mansoni	hypothetical protein	0.0062	0.0237	0.0333
Echinococcus multilocularis	replication factor c subunit 1	0.0015	0.0006	0.0002
Brugia malayi	nuclear receptor RXR	0.0017	0.0017	0.004
Plasmodium vivax	zinc finger protein, putative	0.0015	0.0007	0.0004
Onchocerca volvulus	Huntingtin homolog	0.0128	0.0564	0.1368
Brugia malayi	MH1 domain containing protein	0.0025	0.0056	0.0135
Brugia malayi	nuclear receptor RXR	0.0015	0.0008	0.0018
Giardia lamblia	Protein 21.1	0.0015	0.0007	0.0832
Onchocerca volvulus		0.0314	0.1481	0.3615
Schistosoma mansoni	survival motor neuron protein	0.0115	0.0499	0.0708
Loa Loa (eye worm)	hypothetical protein	0.0015	0.0006	0.0013
Trichomonas vaginalis	conserved hypothetical protein	0.0015	0.0007	0.0018
Brugia malayi	Iron-sulfur cluster assembly accessory protein	0.0115	0.0499	0.122
Schistosoma mansoni	hypothetical protein	0.0842	0.4086	0.5835
Schistosoma mansoni	hypothetical protein	0.0016	0.0009	0.0007
Onchocerca volvulus	Ubiquitin thioesterase ZRANB1 homolog	0.03	0.141	0.3441
Mycobacterium tuberculosis	Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase)	0.0025	0.0057	0.037
Schistosoma mansoni	ecdysone-induced protein 78c (dr-78)	0.0017	0.0017	0.0019
Echinococcus multilocularis	mixed lineage leukemia protein mll	0.0017	0.0018	0.0014
Brugia malayi	Bromodomain containing protein	0.0033	0.0095	0.0233
Echinococcus multilocularis	survival motor neuron protein 1	0.0563	0.2711	0.2708
Loa Loa (eye worm)	hypothetical protein	0.0039	0.0122	0.0298
Brugia malayi	CHE-14 protein	0.0064	0.0248	0.0607
Trichomonas vaginalis	glucosylceramidase, putative	0.0149	0.0665	0.1629
Loa Loa (eye worm)	hypothetical protein	0.0027	0.0065	0.0157
Loa Loa (eye worm)	hypothetical protein	0.0015	0.0004	0.0008
Brugia malayi	RING finger protein 20	0.0015	0.0007	0.0017
Loa Loa (eye worm)	cyclic-nucleotide gated cation channel	0.0015	0.0004	0.0008
Brugia malayi	Pax transcription activation domain interacting protein	0.0015	0.0006	0.0013
Brugia malayi	Muscleblind-like protein	0.048	0.2301	0.5631
Onchocerca volvulus		0.0027	0.0063	0.0141
Mycobacterium leprae	conserved hypothetical protein	0.0039	0.0122	1
Loa Loa (eye worm)	PHD-finger family protein	0.0018	0.002	0.0048
Echinococcus granulosus	sterol regulatory element binding protein	0.0064	0.0248	0.0245
Entamoeba histolytica	hypothetical protein	0.0036	0.011	0.1578
Onchocerca volvulus	Protein neuralized homolog	0.0015	0.0007	0.0004
Loa Loa (eye worm)	SWIB/MDM2 domain-containing protein	0.0842	0.4086	1
Giardia lamblia	Protein 21.1	0.0015	0.0007	0.0832
Trypanosoma brucei	Zinc finger, C3HC4 type (RING finger), putative	0.0015	0.0007	0.0011
Toxoplasma gondii	helicase, putative	0.0015	0.0007	0.0004
Trypanosoma cruzi	UEV domain/Zinc finger, C3HC4 type (RING finger), putative	0.0015	0.0007	0.0011
Trypanosoma cruzi	hypothetical protein, conserved	0.0015	0.0007	0.0011
Echinococcus multilocularis	NADP dependent isocitrate dehydrogenase	0.0017	0.0016	0.0012
Toxoplasma gondii	aldehyde dehydrogenase	0.0195	0.0895	0.218
Brugia malayi	hypothetical protein	0.0017	0.0017	0.004
Schistosoma mansoni	fusion	0.03	0.141	0.201
Brugia malayi	nuclear hormone receptor	0.0032	0.0092	0.0225
Loa Loa (eye worm)	hypothetical protein	0.0046	0.0159	0.0388
Trichomonas vaginalis	RNA polymerase II ctd phosphatase, putative	0.0015	0.0006	0.0014
Echinococcus multilocularis	histone lysine N methyltransferase MLL3	0.0021	0.0036	0.0032
Brugia malayi	Cytochrome P450 family protein	0.0025	0.0054	0.0132
Toxoplasma gondii	histone lysine methyltransferase SET1	0.012	0.0522	0.1264
Giardia lamblia	Protein 21.1	0.0015	0.0007	0.0832
Onchocerca volvulus		0.03	0.141	0.3441
Loa Loa (eye worm)	hypothetical protein	0.0563	0.2711	0.6635
Echinococcus granulosus	lamin dm0	0.0027	0.0063	0.006
Echinococcus granulosus	neuropeptide receptor A26	0.0496	0.2376	0.2373
Loa Loa (eye worm)	hypothetical protein	0.0128	0.0564	0.138
Brugia malayi	MH2 domain containing protein	0.0368	0.1746	0.4274
Schistosoma mansoni	intermediate filament proteins	0.0027	0.0063	0.0085
Brugia malayi	Nuclear hormone receptor-like 1	0.0017	0.0017	0.004
Brugia malayi	hypothetical protein	0.0017	0.0017	0.004
Brugia malayi	latrophilin 2 splice variant baaae	0.0099	0.0422	0.1033
Schistosoma mansoni	histone-lysine n-methyltransferase setb1	0.0063	0.0242	0.034
Leishmania major	hypothetical protein, conserved	0.0015	0.0007	0.000000090562
Schistosoma mansoni	inhibitor of apoptosis 1 diap1	0.0015	0.0007	0.0005
Loa Loa (eye worm)	D-ets-4 DNA binding domain-containing protein	0.0052	0.0189	0.0462
Mycobacterium tuberculosis	Probable esterase LipL	0.0039	0.0122	0.0943
Trypanosoma cruzi	UEV domain/Zinc finger, C3HC4 type (RING finger), putative	0.0015	0.0007	0.0011
Giardia lamblia	Protein 21.1	0.0015	0.0007	0.0832
Brugia malayi	Intermediate filament tail domain containing protein	0.0027	0.0063	0.0154
Loa Loa (eye worm)	hypothetical protein	0.0039	0.0122	0.0298
Trichomonas vaginalis	conserved hypothetical protein	0.0015	0.0007	0.0018
Entamoeba histolytica	acyl-CoA synthetase, putative	0.0036	0.0109	0.1565
Mycobacterium tuberculosis	Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase)	0.0027	0.0065	0.0434
Loa Loa (eye worm)	hypothetical protein	0.0032	0.0092	0.0225
Schistosoma mansoni	methyl-cpg binding protein mbd	0.0015	0.0005	0.0002
Trichomonas vaginalis	esterase, putative	0.0039	0.0122	0.0299
Trichomonas vaginalis	ankyrin repeat-containing protein, putative	0.0015	0.0007	0.0018
Giardia lamblia	Hypothetical protein	0.0015	0.0007	0.0832
Schistosoma mansoni	nuclear receptor	0.0015	0.0008	0.0006
Schistosoma mansoni	mixed-lineage leukemia protein mll	0.0131	0.0579	0.0823
Loa Loa (eye worm)	beta-LACTamase domain containing family member	0.0039	0.0122	0.0298
Trypanosoma cruzi	Zinc finger, C3HC4 type (RING finger), putative	0.0015	0.0007	0.0011
Schistosoma mansoni	photoreceptor-specific nuclear receptor related	0.0032	0.0092	0.0127
Schistosoma mansoni	acetyl-CoA C-acetyltransferase	0.0023	0.0045	0.0059
Trypanosoma brucei	ring finger containing protein	0.0015	0.0007	0.0011
Plasmodium falciparum	ataxin-2 like protein, putative	0.0025	0.0057	0.0126
Echinococcus granulosus	nuclear receptor nhr 48	0.0015	0.0008	0.0004
Echinococcus multilocularis	thyroid hormone receptor alpha	0.0032	0.0092	0.0089
Plasmodium falciparum	SWIB/MDM2 domain-containing protein	0.0842	0.4086	1
Schistosoma mansoni	peter pan-related	0.0015	0.0007	0.0005
Brugia malayi	Nuclear hormone receptor E75	0.0015	0.0008	0.0018
Schistosoma mansoni	hypothetical protein	0.0062	0.0237	0.0333
Plasmodium vivax	trophozoite exported protein 1, putative	0.0015	0.0007	0.0004
Trichomonas vaginalis	penicillin-binding protein, putative	0.0039	0.0122	0.0299
Trichomonas vaginalis	conserved hypothetical protein	0.0015	0.0007	0.0018
Loa Loa (eye worm)	nuclear receptor NHR-67	0.0015	0.0008	0.0018
Loa Loa (eye worm)	MH1 domain-containing protein	0.0025	0.0056	0.0135
Mycobacterium leprae	PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE)	0.0036	0.0109	0.8901
Loa Loa (eye worm)	DR-78	0.0015	0.0008	0.0018
Brugia malayi	topoisomerase	0.0015	0.0006	0.0013
Loa Loa (eye worm)	hypothetical protein	0.0015	0.0008	0.0018
Brugia malayi	Zn-finger in Ran binding protein and others containing protein	0.03	0.141	0.3449
Brugia malayi	beta-lactamase	0.0039	0.0122	0.0298
Giardia lamblia	Protein 21.1	0.0015	0.0007	0.0832
Echinococcus multilocularis	Niemann Pick C1 protein	0.0149	0.0669	0.0665
Trichomonas vaginalis	glucosylceramidase, putative	0.0149	0.0665	0.1629
Schistosoma mansoni	hypothetical protein	0.0046	0.0159	0.0222
Brugia malayi	F/Y-rich N-terminus family protein	0.0022	0.0043	0.0104
Trypanosoma cruzi	UEV domain/Zinc finger, C3HC4 type (RING finger), putative	0.0015	0.0007	0.0011
Trypanosoma cruzi	hypothetical protein	0.0015	0.0007	0.0011
Mycobacterium ulcerans	lipase LipD	0.0039	0.0122	0.1311
Trypanosoma brucei	hypothetical protein, conserved	0.03	0.141	1
Echinococcus multilocularis	muscleblind protein	0.048	0.2301	0.2298
Loa Loa (eye worm)	hypothetical protein	0.0099	0.0422	0.1033
Echinococcus multilocularis	COUP TF:Svp nuclear hormone receptor	0.0032	0.0092	0.0089
Giardia lamblia	Kinase	0.0015	0.0007	0.0832
Toxoplasma gondii	isocitrate dehydrogenase	0.0017	0.0016	0.0024
Brugia malayi	CXXC zinc finger family protein	0.0061	0.0232	0.0567
Echinococcus granulosus	lamin	0.0027	0.0063	0.006
Trypanosoma cruzi	isocitrate dehydrogenase, putative	0.0017	0.0016	0.007
Brugia malayi	hypothetical protein	0.0015	0.0007	0.0017
Schistosoma mansoni	smad1 5 8 and	0.0025	0.0056	0.0074
Loa Loa (eye worm)	hypothetical protein	0.0036	0.0109	0.0267
Brugia malayi	Ligand-binding domain of nuclear hormone receptor family protein	0.0032	0.0092	0.0225
Brugia malayi	Nuclear hormone receptor family member nhr-31	0.0032	0.0092	0.0225
Mycobacterium ulcerans	long-chain-fatty-acid--CoA ligase	0.0036	0.0109	0.1167
Schistosoma mansoni	hypothetical protein	0.0046	0.0159	0.0222
Plasmodium vivax	isocitrate dehydrogenase [NADP], mitochondrial, putative	0.0017	0.0016	0.0024
Onchocerca volvulus	Huntingtin homolog	0.0128	0.0564	0.1368
Trichomonas vaginalis	ubiquitin-protein ligase BRE1, putative	0.0015	0.0007	0.0018
Brugia malayi	hypothetical protein	0.0015	0.0006	0.0013
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-31	0.0032	0.0092	0.0225
Entamoeba histolytica	Niemann-Pick C1 protein, putative	0.0149	0.0669	1
Plasmodium vivax	DNA repair protein RAD5, putative	0.0015	0.0007	0.0004
Brugia malayi	nuclear receptor NHR-88	0.0032	0.0092	0.0225
Mycobacterium tuberculosis	Conserved protein	0.0039	0.0122	0.0943
Schistosoma mansoni	topbp1	0.0015	0.0006	0.0003
Schistosoma mansoni	nuclear hormone receptor superfamily protein-related	0.0015	0.0008	0.0006
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-40	0.0032	0.0092	0.0225
Trypanosoma cruzi	WLM domain containing protein, putative	0.03	0.141	1
Schistosoma mansoni	zinc finger protein	0.0015	0.0007	0.0005
Brugia malayi	Nuclear hormone receptor-like 1	0.0017	0.0017	0.004
Trichomonas vaginalis	sex-determining protein fem-1, putative	0.0015	0.0007	0.0018
Trypanosoma brucei	hypothetical protein, conserved	0.0039	0.0122	0.083
Giardia lamblia	Kinase, NEK	0.0015	0.0007	0.0832
Echinococcus multilocularis	ring finger protein 170	0.0015	0.0007	0.0004
Loa Loa (eye worm)	beta-lactamase	0.0039	0.0122	0.0298
Leishmania major	hypothetical protein, conserved	0.03	0.141	1
Toxoplasma gondii	SWI2/SNF2-containing protein RAD5	0.0015	0.0007	0.0004
Brugia malayi	Nuclear hormone receptor family member nhr-40	0.0032	0.0092	0.0225
Trichomonas vaginalis	RNA polymerase II ctd phosphatase, putative	0.0015	0.0006	0.0014
Brugia malayi	hypothetical protein	0.0016	0.0013	0.003
Trypanosoma cruzi	UEV domain/Zinc finger, C3HC4 type (RING finger), putative	0.0015	0.0007	0.0011
Schistosoma mansoni	smad1 5 8 and	0.0025	0.0056	0.0074
Onchocerca volvulus		0.03	0.141	0.3441
Echinococcus granulosus	hepatocyte nuclear factor 4 alpha	0.0032	0.0092	0.0089
Trypanosoma cruzi	UEV domain/Zinc finger, C3HC4 type (RING finger), putative	0.0015	0.0007	0.0011
Schistosoma mansoni	ring finger protein 151	0.0015	0.0007	0.0005
Trypanosoma cruzi	Zn-finger in Ran binding protein and others, putative	0.03	0.141	1
Trypanosoma cruzi	hypothetical protein, conserved	0.0015	0.0007	0.0011
Schistosoma mansoni	niemann-pick C1 (NPC1)	0.0152	0.068	0.0967
Trichomonas vaginalis	conserved hypothetical protein	0.0015	0.0006	0.0014
Loa Loa (eye worm)	hypothetical protein	0.0039	0.0122	0.0298
Trichomonas vaginalis	glucosylceramidase, putative	0.0215	0.0993	0.243
Loa Loa (eye worm)	hypothetical protein	0.0061	0.0234	0.0571
Onchocerca volvulus		0.0489	0.2345	0.5732
Loa Loa (eye worm)	hypothetical protein	0.0027	0.0063	0.0154
Brugia malayi	ecdysone receptor	0.0015	0.0008	0.0018
Entamoeba histolytica	zinc finger domain containing protein	0.0015	0.0007	0.0023
Echinococcus granulosus	zinc finger protein	0.002	0.0033	0.0029
Schistosoma mansoni	zinc finger protein	0.002	0.0033	0.0041
Schistosoma mansoni	voltage-gated potassium channel	0.0021	0.0037	0.0048
Echinococcus multilocularis	histone lysine N methyltransferase MLL3	0.0017	0.0018	0.0014
Trypanosoma cruzi	hypothetical protein, conserved	0.0015	0.0007	0.0011
Brugia malayi	hypothetical protein	0.0015	0.0006	0.0013
Onchocerca volvulus		0.0015	0.0007	0.0004
Brugia malayi	hypothetical protein	0.0015	0.0008	0.0018
Loa Loa (eye worm)	hypothetical protein	0.0033	0.0096	0.0233
Entamoeba histolytica	hypothetical protein	0.0036	0.011	0.1578
Trichomonas vaginalis	conserved hypothetical protein	0.0015	0.0007	0.0018
Onchocerca volvulus	Glucosylceramidase homolog	0.0141	0.0628	0.1525
Echinococcus multilocularis	ecdysone induced protein 78C	0.0032	0.0092	0.0089
Trichomonas vaginalis	conserved hypothetical protein	0.0015	0.0007	0.0018
Brugia malayi	calcium-independent alpha-latrotoxin receptor 2, putative	0.0046	0.0159	0.0388
Schistosoma mansoni	ets-related	0.0158	0.0713	0.1013
Loa Loa (eye worm)	hypothetical protein	0.0015	0.0008	0.0018
Trichomonas vaginalis	ubiquitin-protein ligase BRE1, putative	0.0015	0.0007	0.0018
Toxoplasma gondii	Zn-finger in Ran binding protein and others domain-containing protein	0.03	0.141	0.3441
Brugia malayi	B-box zinc finger family protein	0.0015	0.0007	0.0017
Mycobacterium ulcerans	beta-lactamase	0.0039	0.0122	0.1311
Brugia malayi	hypothetical protein	0.0015	0.0007	0.0017
Echinococcus granulosus	Upstream activation factor subunit UAF30	0.0842	0.4086	0.4084
Echinococcus granulosus	bromodomain adjacent to zinc finger domain	0.0031	0.0085	0.0082
Trichomonas vaginalis	glucosylceramidase, putative	0.0141	0.0628	0.1537
Trypanosoma cruzi	UEV domain/Zinc finger, C3HC4 type (RING finger), putative	0.0015	0.0007	0.0011
Echinococcus multilocularis	dnaJ subfamily B	0.0866	0.4204	0.4202
Trypanosoma cruzi	UEV domain/Zinc finger, C3HC4 type (RING finger), putative	0.0015	0.0007	0.0011
Plasmodium falciparum	AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative	0.0019	0.0024	0.0044
Loa Loa (eye worm)	fli-1 protein	0.0158	0.0713	0.1743
Loa Loa (eye worm)	isocitrate dehydrogenase	0.0017	0.0016	0.0037
Trypanosoma cruzi	hypothetical protein, conserved	0.0015	0.0007	0.0011
Trypanosoma cruzi	hypothetical protein, conserved	0.0039	0.0122	0.083
Onchocerca volvulus		0.0015	0.0007	0.0004
Brugia malayi	Calcitonin receptor-like protein seb-1	0.0145	0.0649	0.1588
Leishmania major	4-coumarate:coa ligase-like protein	0.0036	0.0109	0.0729
Trichomonas vaginalis	conserved hypothetical protein	0.0015	0.0007	0.0018
Echinococcus multilocularis	isocitrate dehydrogenase 2 (NADP+)	0.0017	0.0016	0.0012
Leishmania major	aldehyde dehydrogenase, mitochondrial precursor	0.0195	0.0895	0.633
Trypanosoma cruzi	PAB1-binding protein , putative	0.0025	0.0057	0.0365
Brugia malayi	Isocitrate dehydrogenase	0.0017	0.0016	0.0037
Schistosoma mansoni	rnf5	0.0015	0.0007	0.0005
Trypanosoma cruzi	Zinc finger, C3HC4 type (RING finger), putative	0.0015	0.0007	0.0011
Schistosoma mansoni	hypothetical protein	0.0182	0.0828	0.1178
Trichomonas vaginalis	conserved hypothetical protein	0.0015	0.0007	0.0018
Brugia malayi	Nuclear hormone receptor family member nhr-25	0.0032	0.0092	0.0225
Brugia malayi	brahma associated protein 60 kDa	0.0842	0.4086	1
Onchocerca volvulus	Nuclear receptor subfamily 6 group A member 1 homolog	0.0015	0.0008	0.0005
Brugia malayi	steroid hormone receptor	0.0032	0.0092	0.0225
Trichomonas vaginalis	ankyrin repeat-containing protein, putative	0.0015	0.0007	0.0018
Schistosoma mansoni	serine/threonine protein kinase	0.0015	0.0007	0.0005
Mycobacterium tuberculosis	Probable conserved lipoprotein	0.0039	0.0122	0.0943
Trichomonas vaginalis	ankyrin repeat domain protein, putative	0.0015	0.0007	0.0018
Echinococcus multilocularis	nuclear receptor 2DBD gamma	0.0032	0.0092	0.0089
Plasmodium falciparum	E3 ubiquitin-protein ligase, putative	0.0015	0.0007	0.0004
Trypanosoma brucei	Zinc finger, C3HC4 type (RING finger), putative	0.0015	0.0007	0.0011
Trichomonas vaginalis	ubiquitin-protein ligase BRE1, putative	0.0015	0.0007	0.0018
Trichomonas vaginalis	conserved hypothetical protein	0.0842	0.4086	1
Loa Loa (eye worm)	hypothetical protein	0.0015	0.0008	0.0018
Plasmodium vivax	E3 ubiquitin-protein ligase RNF5, putative	0.0015	0.0007	0.0004
Echinococcus granulosus	ring finger protein 170	0.0015	0.0007	0.0004
Mycobacterium tuberculosis	Conserved protein	0.0039	0.0122	0.0943
Schistosoma mansoni	cpg binding protein	0.0066	0.0257	0.0362
Plasmodium falciparum	trophozoite exported protein 1	0.0015	0.0007	0.0004
Brugia malayi	hypothetical protein	0.0015	0.0007	0.0017
Loa Loa (eye worm)	hypothetical protein	0.0017	0.0017	0.004
Brugia malayi	Fli-1 protein	0.0158	0.0713	0.1743
Echinococcus multilocularis	nuclear receptor subfamily 4 group A	0.0015	0.0008	0.0004
Echinococcus granulosus	histone lysine N methyltransferase MLL3	0.0021	0.0036	0.0032
Loa Loa (eye worm)	hypothetical protein	0.03	0.141	0.3449
Trichomonas vaginalis	penicillin-binding protein, putative	0.0039	0.0122	0.0299
Loa Loa (eye worm)	MH2 domain-containing protein	0.0368	0.1746	0.4274
Loa Loa (eye worm)	hypothetical protein	0.0015	0.0008	0.0018
Loa Loa (eye worm)	hypothetical protein	0.03	0.141	0.3449
Trypanosoma cruzi	hypothetical protein	0.0015	0.0007	0.0011
Schistosoma mansoni	nuclear receptor 2DBD-gamma	0.0032	0.0092	0.0127
Brugia malayi	Cyclic-nucleotide gated cation channel	0.0015	0.0004	0.0008
Trypanosoma cruzi	Plus-3 domain/Zinc finger, C3HC4 type (RING finger), putative	0.0015	0.0007	0.0011
Mycobacterium ulcerans	acyl-CoA synthetase	0.0036	0.0109	0.1167
Loa Loa (eye worm)	RING finger protein 20	0.0015	0.0007	0.0017
Echinococcus granulosus	muscleblind protein	0.048	0.2301	0.2298
Schistosoma mansoni	hypothetical protein	0.0062	0.0237	0.0333
Loa Loa (eye worm)	hypothetical protein	0.0015	0.0006	0.0013
Brugia malayi	MH2 domain containing protein	0.0025	0.0056	0.0135
Brugia malayi	Zinc finger, C2H2 type family protein	0.0015	0.0007	0.0017
Toxoplasma gondii	hypothetical protein	0.0015	0.0007	0.0004
Mycobacterium ulcerans	fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE	0.0039	0.0122	0.1311
Echinococcus granulosus	intermediate filament protein	0.0027	0.0063	0.006
Loa Loa (eye worm)	hypothetical protein	0.0015	0.0008	0.0018
Loa Loa (eye worm)	hypothetical protein	0.03	0.141	0.3449
Trichomonas vaginalis	conserved hypothetical protein	0.0015	0.0007	0.0018
Brugia malayi	YY1-associated factor 2	0.03	0.141	0.3449
Loa Loa (eye worm)	pre-SET domain-containing protein family protein	0.043	0.2053	0.5023
Loa Loa (eye worm)	histone methyltransferase	0.0021	0.0036	0.0087
Trypanosoma cruzi	cytochrome P450, putative	0.0025	0.0054	0.0347
Loa Loa (eye worm)	hypothetical protein	0.0032	0.0092	0.0225
Brugia malayi	isocitrate dehydrogenase	0.0017	0.0016	0.0037
Echinococcus multilocularis	E3 ubiquitin protein ligase MYLIP	0.0015	0.0007	0.0004
Brugia malayi	Nuclear hormone receptor family member nhr-1	0.0032	0.0092	0.0225
Trypanosoma cruzi	Zinc finger, C3HC4 type (RING finger), putative	0.0015	0.0007	0.0011
Echinococcus granulosus	dnaJ subfamily B	0.0866	0.4204	0.4202
Schistosoma mansoni	RAR-like nuclear receptor	0.0032	0.0092	0.0127
Trypanosoma brucei	Zinc finger, C3HC4 type (RING finger), putative	0.0015	0.0007	0.0011
Brugia malayi	nuclear hormone receptor family member nhr-6	0.0015	0.0008	0.0018
Echinococcus granulosus	E3 ubiquitin protein ligase mib1	0.0015	0.0007	0.0004
Schistosoma mansoni	voltage-gated potassium channel	0.008	0.0328	0.0463
Schistosoma mansoni	gabp alpha	0.0052	0.0189	0.0265
Schistosoma mansoni	voltage-gated potassium channel	0.0021	0.0037	0.0048
Schistosoma mansoni	Tr4/Tr2 (homologue)	0.0032	0.0092	0.0127
Trichomonas vaginalis	ankyrin 2,3/unc44, putative	0.0015	0.0007	0.0018
Trypanosoma cruzi	hypothetical protein, conserved	0.03	0.141	1
Brugia malayi	nuclear hormone receptor family member odr-7	0.0015	0.0008	0.0018
Echinococcus multilocularis	zinc finger protein	0.002	0.0033	0.0029
Echinococcus multilocularis	Nuclear hormone receptor family member nhr 41	0.0032	0.0092	0.0089
Echinococcus multilocularis	diuretic hormone 44 receptor GPRdih2	0.0046	0.0159	0.0155
Giardia lamblia	Protein 21.1	0.0015	0.0007	0.0832
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-49	0.0032	0.0092	0.0225
Brugia malayi	AMP-binding enzyme family protein	0.0036	0.0109	0.0267
Brugia malayi	Pre-SET motif family protein	0.043	0.2053	0.5023
Loa Loa (eye worm)	hypothetical protein	0.0021	0.0037	0.009
Trichomonas vaginalis	cell cycle control protein cwf24, putative	0.0016	0.0009	0.0021
Schistosoma mansoni	hypothetical protein	0.0842	0.4086	0.5835
Echinococcus granulosus	microtubule associated protein 2	0.1433	0.7	0.6998
Loa Loa (eye worm)	hypothetical protein	0.0015	0.0008	0.0018
Echinococcus multilocularis	smad	0.0025	0.0056	0.0052
Loa Loa (eye worm)	transcription factor SMAD2	0.0368	0.1746	0.4274
Trichomonas vaginalis	ion channel nompc, putative	0.0015	0.0007	0.0018
Trichomonas vaginalis	conserved hypothetical protein	0.0015	0.0007	0.0018
Echinococcus multilocularis	GA binding protein alpha chain	0.0052	0.0189	0.0186
Chlamydia trachomatis	acylglycerophosphoethanolamine acyltransferase	0.0027	0.0065	0.0144
Toxoplasma gondii	histone lysine methyltransferase SET/SUV39	0.0063	0.0242	0.0579
Trypanosoma cruzi	Ankyrin repeats (3 copies)/Zinc finger, C3HC4 type (RING finger), putative	0.0015	0.0007	0.0011
Echinococcus granulosus	Niemann Pick C1 protein	0.0149	0.0669	0.0665
Onchocerca volvulus		0.0015	0.0007	0.0004
Trichomonas vaginalis	conserved hypothetical protein	0.0015	0.0007	0.0018
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-1	0.0032	0.0092	0.0225
Echinococcus multilocularis	GPCR, family 2	0.0046	0.0159	0.0155
Echinococcus granulosus	E3 ubiquitin protein ligase RNF146	0.0015	0.0007	0.0004
Echinococcus granulosus	Nuclear pore complex protein Nup153	0.03	0.141	0.1406
Mycobacterium tuberculosis	Possible conserved lipoprotein LpqK	0.0039	0.0122	0.0943
Trypanosoma cruzi	PAB1-binding protein , putative	0.0025	0.0057	0.0365
Schistosoma mansoni	hypothetical protein	0.0015	0.0007	0.0005
Echinococcus granulosus	beta LACTamase domain containing family member	0.0039	0.0122	0.0119
Giardia lamblia	Protein 21.1	0.0015	0.0007	0.0832
Schistosoma mansoni	aldehyde dehydrogenase	0.0195	0.0895	0.1274
Entamoeba histolytica	zinc finger domain containing protein	0.0015	0.0007	0.0023
Schistosoma mansoni	hypothetical protein	0.0015	0.0007	0.0005
Echinococcus granulosus	nuclear receptor subfamily 4 group A	0.0015	0.0008	0.0004
Trypanosoma cruzi	UEV domain/Zinc finger, C3HC4 type (RING finger), putative	0.0015	0.0007	0.0011
Loa Loa (eye worm)	hypothetical protein	0.0032	0.0092	0.0225
Loa Loa (eye worm)	hypothetical protein	0.0064	0.0248	0.0607
Echinococcus multilocularis	Zinc finger, RanBP2 type	0.03	0.141	0.1406
Echinococcus granulosus	nuclear receptor subfamily 1 group D	0.0017	0.0017	0.0013
Echinococcus granulosus	mothers against decapentaplegic 5	0.0025	0.0056	0.0052
Chlamydia trachomatis	DNA topoisomerase I	0.0842	0.4086	1
Schistosoma mansoni	peter pan-related	0.0015	0.0007	0.0005
Loa Loa (eye worm)	hypothetical protein	0.0299	0.1406	0.344
Entamoeba histolytica	exodeoxyribonuclease III, putative	0.0019	0.0024	0.0271
Leishmania major	hypothetical protein, conserved	0.0039	0.0122	0.0821
Chlamydia trachomatis	SWIB complex protein	0.0842	0.4086	1
Echinococcus granulosus	5'partial\|histone lysine N methyltransferase SETDB2	0.0059	0.0224	0.022
Echinococcus granulosus	Basic leucine zipper bZIP transcription	0.0036	0.011	0.0107
Schistosoma mansoni	patched 1	0.0064	0.0248	0.035
Trypanosoma brucei	isocitrate dehydrogenase [NADP], mitochondrial precursor, putative	0.0017	0.0016	0.007
Mycobacterium tuberculosis	Probable aldehyde dehydrogenase	0.0195	0.0895	0.7768
Echinococcus granulosus	COUP TF:Svp nuclear hormone receptor	0.0032	0.0092	0.0089
Brugia malayi	hypothetical protein	0.0015	0.0007	0.0017
Giardia lamblia	Protein 21.1	0.0015	0.0007	0.0832
Plasmodium falciparum	isocitrate dehydrogenase [NADP], mitochondrial	0.0017	0.0016	0.0024
Loa Loa (eye worm)	hypothetical protein	0.0015	0.0006	0.0013
Trichomonas vaginalis	conserved hypothetical protein	0.0015	0.0006	0.0014
Onchocerca volvulus	Bile acid receptor homolog	0.0032	0.0092	0.0212
Schistosoma mansoni	family S12 unassigned peptidase (S12 family)	0.0039	0.0122	0.017
Brugia malayi	ATP dependent DNA ligase C terminal region family protein	0.0015	0.0006	0.0013
Brugia malayi	Zn-finger in Ran binding protein and others containing protein	0.03	0.141	0.3449
Trichomonas vaginalis	conserved hypothetical protein	0.0064	0.0248	0.0608
Loa Loa (eye worm)	hypothetical protein	0.0078	0.0315	0.0769
Leishmania major	hypothetical protein, conserved	0.03	0.141	1
Schistosoma mansoni	smad	0.0025	0.0056	0.0074
Trichomonas vaginalis	conserved hypothetical protein	0.0015	0.0007	0.0018
Schistosoma mansoni	microtubule-associated protein tau	0.1433	0.7	1
Loa Loa (eye worm)	hypothetical protein	0.0015	0.0007	0.0017
Mycobacterium ulcerans	acyl-CoA synthetase	0.0036	0.0109	0.1167
Toxoplasma gondii	zinc finger, C3HC4 type (RING finger) domain-containing protein	0.0015	0.0007	0.0004
Trichomonas vaginalis	conserved hypothetical protein	0.0015	0.0007	0.0018
Schistosoma mansoni	nuclear hormone receptor nor-1/nor-2	0.0032	0.0092	0.0127
Giardia lamblia	Protein 21.1	0.0015	0.0007	0.0832
Trypanosoma brucei	Zn-finger in Ran binding protein and others/FYVE zinc finger, putative	0.03	0.141	1
Giardia lamblia	Protein 21.1	0.0015	0.0007	0.0832
Echinococcus multilocularis	mothers against decapentaplegic 5	0.0025	0.0056	0.0052
Echinococcus multilocularis	lamin dm0	0.0027	0.0063	0.006
Schistosoma mansoni	transcription factor LCR-F1	0.0036	0.011	0.0152
Echinococcus multilocularis	potassium voltage gated channel subfamily H	0.0021	0.0037	0.0033
Echinococcus granulosus	thyroid hormone receptor alpha	0.0015	0.0008	0.0004
Loa Loa (eye worm)	Smad1	0.0025	0.0056	0.0135
Loa Loa (eye worm)	hypothetical protein	0.0015	0.0008	0.0018
Schistosoma mansoni	nuclear hormone receptor	0.0015	0.0008	0.0006
Echinococcus multilocularis	histone lysine N methyltransferase SETMAR	0.0063	0.0242	0.0238
Brugia malayi	Steroid receptor seven-up type 2	0.0032	0.0092	0.0225
Echinococcus multilocularis	nuclear receptor nhr 48	0.0015	0.0008	0.0004
Onchocerca volvulus		0.0015	0.0008	0.0005
Echinococcus granulosus	diuretic hormone 44 receptor GPRdih2	0.0046	0.0159	0.0155
Trichomonas vaginalis	chromosome transmission fidelity factor, putative	0.0015	0.0006	0.0014
Toxoplasma gondii	hypothetical protein	0.0015	0.0007	0.0004
Brugia malayi	Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog	0.0073	0.0294	0.0719
Echinococcus granulosus	fetal alzheimer antigen falz	0.0023	0.0045	0.0042
Schistosoma mansoni	TGF-beta signal transducer Smad2	0.0025	0.0056	0.0074
Onchocerca volvulus		0.0015	0.0007	0.0004
Mycobacterium ulcerans	cytochrome P450 185A4 Cyp185A4	0.0025	0.0054	0.0548
Echinococcus multilocularis	bromodomain adjacent to zinc finger domain	0.0055	0.0204	0.02
Echinococcus multilocularis	SWI:SNF matrix associated	0.0842	0.4086	0.4084
Giardia lamblia	Protein 21.1	0.0015	0.0007	0.0832
Brugia malayi	brahma associated protein 60 kDa	0.0842	0.4086	1
Loa Loa (eye worm)	hypothetical protein	0.0128	0.0564	0.138
Schistosoma mansoni	mixed-lineage leukemia protein mll	0.0017	0.0018	0.002
Brugia malayi	Nuclear hormone receptor family member nhr-25	0.0032	0.0092	0.0225
Loa Loa (eye worm)	bromodomain containing protein	0.0015	0.0007	0.0017
Brugia malayi	Nuclear hormone receptor family member nhr-49	0.0032	0.0092	0.0225
Trichomonas vaginalis	ap endonuclease, putative	0.0019	0.0024	0.0058
Loa Loa (eye worm)	hypothetical protein	0.0015	0.0007	0.0017
Echinococcus multilocularis	SWI:SNF matrix associated	0.0842	0.4086	0.4084
Trypanosoma cruzi	apurinic/apyrimidinic endonuclease	0.0019	0.0024	0.0128
Brugia malayi	Zn-finger in Ran binding protein and others containing protein	0.03	0.141	0.3449
Loa Loa (eye worm)	hypothetical protein	0.0314	0.1481	0.3623
Echinococcus granulosus	expressed conserved protein	0.014	0.0624	0.0621
Schistosoma mansoni	cpg binding protein	0.0061	0.0232	0.0326
Trichomonas vaginalis	conserved hypothetical protein	0.0015	0.0007	0.0018
Loa Loa (eye worm)	hypothetical protein	0.0015	0.0006	0.0013
Trichomonas vaginalis	ankyrin, putative	0.0015	0.0007	0.0018
Trypanosoma brucei	Plus-3 domain/Zinc finger, C3HC4 type (RING finger), putative	0.0015	0.0007	0.0011
Trichomonas vaginalis	ankyrin, putative	0.0015	0.0007	0.0018
Mycobacterium tuberculosis	Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase)	0.0036	0.0109	0.083
Loa Loa (eye worm)	hypothetical protein	0.0015	0.0007	0.0017
Echinococcus granulosus	potassium voltage gated channel subfamily H	0.0073	0.0294	0.0291
Echinococcus granulosus	methyl CpG binding domain protein 2	0.0015	0.0005	0.0001
Trichomonas vaginalis	voltage and ligand gated potassium channel, putative	0.0069	0.0271	0.0662
Echinococcus multilocularis	hepatocyte nuclear factor 4 alpha	0.0032	0.0092	0.0089
Schistosoma mansoni	bromodomain containing protein	0.0058	0.0219	0.0308
Onchocerca volvulus	Nuclear receptor subfamily 6 group A member 1 homolog	0.0015	0.0008	0.0005
Trypanosoma cruzi	hypothetical protein, conserved	0.0015	0.0007	0.0011
Echinococcus multilocularis	fetal alzheimer antigen, falz	0.0023	0.0045	0.0042
Trypanosoma cruzi	Zinc finger, C3HC4 type (RING finger), putative	0.0015	0.0007	0.0011
Loa Loa (eye worm)	pigment dispersing factor receptor c	0.0145	0.0649	0.1588
Echinococcus multilocularis	Smad4	0.0025	0.0056	0.0052
Trichomonas vaginalis	glucosylceramidase, putative	0.0215	0.0993	0.243
Brugia malayi	PHD-finger family protein	0.0025	0.0055	0.0135
Trichomonas vaginalis	set domain proteins, putative	0.0489	0.2345	0.5738
Trichomonas vaginalis	glucosylceramidase, putative	0.0141	0.0628	0.1537
Schistosoma mansoni	hypothetical protein	0.0182	0.0828	0.1178
Loa Loa (eye worm)	hypothetical protein	0.0032	0.0092	0.0225
Mycobacterium tuberculosis	Probable lipase LipD	0.0039	0.0122	0.0943
Loa Loa (eye worm)	hypothetical protein	0.0039	0.0122	0.0298
Trichomonas vaginalis	glucosylceramidase, putative	0.0141	0.0628	0.1537
Schistosoma mansoni	hypothetical protein	0.0842	0.4086	0.5835
Schistosoma mansoni	hypothetical protein	0.0018	0.002	0.0023
Brugia malayi	AMP-binding enzyme family protein	0.0036	0.0109	0.0267
Trichomonas vaginalis	ankyrin repeat-containing protein, putative	0.0015	0.0007	0.0018
Plasmodium vivax	hypothetical protein, conserved	0.0842	0.4086	1
Trypanosoma brucei	Zinc finger, C3HC4 type (RING finger) containing protein, putative	0.0015	0.0007	0.0011
Loa Loa (eye worm)	hypothetical protein	0.0015	0.0007	0.0017
Schistosoma mansoni	nuclear hormone receptor	0.0032	0.0092	0.0127
Loa Loa (eye worm)	nuclear hormone receptor	0.0015	0.0008	0.0018
Trypanosoma cruzi	WLM domain containing protein, putative	0.03	0.141	1
Echinococcus granulosus	ring finger protein 113a	0.0016	0.0009	0.0005
Mycobacterium tuberculosis	Possible penicillin-binding protein	0.0246	0.1148	1
Giardia lamblia	Protein 21.1	0.0015	0.0007	0.0832
Loa Loa (eye worm)	steroid hormone receptor	0.0032	0.0092	0.0225
Echinococcus multilocularis		0.0015	0.0007	0.0004
Echinococcus granulosus	Smad4	0.0025	0.0056	0.0052
Entamoeba histolytica	SPRY domain protein	0.0015	0.0007	0.0023
Echinococcus granulosus	neuropeptide s receptor	0.0496	0.2376	0.2373
Loa Loa (eye worm)	hypothetical protein	0.0032	0.0092	0.0225
Schistosoma mansoni	NADP-specific isocitrate dehydrogenase	0.0017	0.0016	0.0017
Brugia malayi	hypothetical protein	0.0015	0.0008	0.0018
Onchocerca volvulus		0.0032	0.0092	0.0212
Loa Loa (eye worm)	hypothetical protein	0.004	0.0131	0.032
Loa Loa (eye worm)	hypothetical protein	0.0032	0.0092	0.0225
Loa Loa (eye worm)	hypothetical protein	0.0145	0.0649	0.1588
Brugia malayi	ecdysteroid receptor	0.0032	0.0092	0.0225
Schistosoma mansoni	hypothetical protein	0.0115	0.0499	0.0708
Mycobacterium ulcerans	esterase/lipase LipP	0.0039	0.0122	0.1311
Trichomonas vaginalis	chromosome transmission fidelity factor, putative	0.0015	0.0006	0.0014
Loa Loa (eye worm)	hypothetical protein	0.0015	0.0008	0.0018
Giardia lamblia	Hypothetical protein	0.0015	0.0007	0.0832
Trypanosoma brucei	Zinc finger, C3HC4 type (RING finger), putative	0.0015	0.0007	0.0011
Giardia lamblia	Protein 21.1	0.0015	0.0007	0.0832
Onchocerca volvulus	Steroid hormone receptor family member cnr14 homolog	0.0032	0.0092	0.0212
Loa Loa (eye worm)	hypothetical protein	0.0027	0.0065	0.0157
Loa Loa (eye worm)	voltage and ligand gated potassium channel	0.0073	0.0294	0.0719
Plasmodium falciparum	zinc finger Ran-binding domain-containing protein 2, putative	0.03	0.141	0.3441
Loa Loa (eye worm)	nuclear receptor nhr-7B	0.0015	0.0008	0.0018
Brugia malayi	Pre-SET motif family protein	0.0063	0.0242	0.0591
Loa Loa (eye worm)	hypothetical protein	0.0045	0.0152	0.0371
Schistosoma mansoni	brg-1 associated factor	0.0842	0.4086	0.5835
Schistosoma mansoni	hypothetical protein	0.0099	0.0422	0.0598
Mycobacterium ulcerans	aldehyde dehydrogenase	0.0195	0.0895	1
Schistosoma mansoni	hypothetical protein	0.0062	0.0237	0.0333
Giardia lamblia	Protein 21.1	0.0015	0.0007	0.0832
Trypanosoma cruzi	Zinc finger, C3HC4 type (RING finger), putative	0.0015	0.0007	0.0011
Trypanosoma brucei	PAB1-binding protein , putative	0.0025	0.0057	0.0365
Loa Loa (eye worm)	cytochrome P450 family protein	0.0025	0.0054	0.0132
Trypanosoma cruzi	Zinc finger, C3HC4 type (RING finger), putative	0.0015	0.0007	0.0011
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-14	0.0032	0.0092	0.0225
Trypanosoma cruzi	Ankyrin repeats (3 copies)/Zinc finger, C3HC4 type (RING finger), putative	0.0015	0.0007	0.0011
Brugia malayi	orphan nuclear receptor NR2E1	0.0015	0.0008	0.0018
Echinococcus multilocularis	histone lysine methyltransferase setb histone lysine methyltransferase eggless	0.0078	0.0315	0.0311
Loa Loa (eye worm)	RiNg Finger protein family member	0.0016	0.0009	0.002
Loa Loa (eye worm)	CXXC zinc finger family protein	0.0061	0.0232	0.0567
Giardia lamblia	Hypothetical protein	0.0015	0.0007	0.0832
Onchocerca volvulus		0.0039	0.0122	0.0286
Loa Loa (eye worm)	intermediate filament protein	0.0027	0.0063	0.0154
Echinococcus multilocularis	atpase aaa+ type core atpase aaa type core	0.1906	0.9332	0.9332
Echinococcus multilocularis	Nuclear pore complex protein Nup153	0.03	0.141	0.1406
Echinococcus multilocularis	E3 ubiquitin protein ligase Bre1	0.0015	0.0007	0.0004
Giardia lamblia	Hypothetical protein	0.0015	0.0007	0.0832
Loa Loa (eye worm)	hypothetical protein	0.0017	0.0017	0.004
Leishmania major	hypothetical protein, conserved	0.0025	0.0057	0.0355
Echinococcus multilocularis	Niemann Pick C1 protein	0.0214	0.0985	0.0982
Toxoplasma gondii	ABC1 family protein	0.0039	0.0122	0.0286
Echinococcus granulosus	nuclear receptor 2DBD gamma	0.0032	0.0092	0.0089
Onchocerca volvulus		0.0061	0.0232	0.0554
Mycobacterium ulcerans	long-chain-fatty-acid-CoA ligase	0.0036	0.0109	0.1167
Loa Loa (eye worm)	exodeoxyribonuclease III family protein	0.0019	0.0024	0.0057
Plasmodium falciparum	ataxin-2 like protein, putative	0.0025	0.0057	0.0126
Schistosoma mansoni	histone-lysine n-methyltransferase setb1	0.0078	0.0315	0.0444
Onchocerca volvulus		0.0842	0.4086	1
Loa Loa (eye worm)	hypothetical protein	0.0015	0.0006	0.0013
Schistosoma mansoni	retinoid-x-receptor (RXR)	0.0017	0.0017	0.0019
Loa Loa (eye worm)	hypothetical protein	0.0017	0.0017	0.004
Toxoplasma gondii	RING zinc finger protein	0.0015	0.0007	0.0004
Onchocerca volvulus		0.0015	0.0008	0.0005
Brugia malayi	intermediate filament protein	0.0027	0.0063	0.0154
Echinococcus granulosus	smad	0.0025	0.0056	0.0052
Loa Loa (eye worm)	hypothetical protein	0.03	0.141	0.3449
Trypanosoma cruzi	Zinc finger, C3HC4 type (RING finger)/EF-hand domain pair, putative	0.0015	0.0007	0.0011
Plasmodium vivax	AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative	0.0019	0.0024	0.0044
Onchocerca volvulus		0.03	0.141	0.3441
Loa Loa (eye worm)	hypothetical protein	0.0036	0.0109	0.0267
Schistosoma mansoni	retinoid-x-receptor (RXR)	0.0032	0.0092	0.0127
Treponema pallidum	exodeoxyribonuclease (exoA)	0.0019	0.0024	1
Entamoeba histolytica	hypothetical protein	0.0015	0.0007	0.0023
Trypanosoma brucei	Zinc finger, C3HC4 type (RING finger), putative	0.0015	0.0007	0.0011
Loa Loa (eye worm)	hypothetical protein	0.048	0.2301	0.5631
Loa Loa (eye worm)	O-glycosyl hydrolase family 30 protein	0.0215	0.0993	0.2429
Brugia malayi	AMP-binding enzyme family protein	0.0036	0.0109	0.0267
Echinococcus multilocularis	potassium voltage gated channel subfamily H	0.0073	0.0294	0.0291
Loa Loa (eye worm)	hypothetical protein	0.0015	0.0007	0.0017
Brugia malayi	beta-lactamase family protein	0.0039	0.0122	0.0298
Echinococcus multilocularis	TGF beta signal transducer SmadC	0.0025	0.0056	0.0052
Mycobacterium tuberculosis	Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase)	0.0025	0.0057	0.037
Mycobacterium tuberculosis	Conserved protein	0.0039	0.0122	0.0943
Giardia lamblia	Protein 21.1	0.0015	0.0007	0.0832
Trichomonas vaginalis	glucosylceramidase, putative	0.0215	0.0993	0.243
Echinococcus granulosus	retinoic acid receptor rxr beta a	0.0032	0.0092	0.0089
Echinococcus granulosus	mixed lineage leukemia protein mll	0.0017	0.0018	0.0014
Mycobacterium tuberculosis	Probable esterase/lipase LipP	0.0039	0.0122	0.0943
Onchocerca volvulus	Putative RING finger protein 207	0.0015	0.0007	0.0004
Brugia malayi	Bromodomain containing protein	0.0068	0.0269	0.0658
Trypanosoma brucei	apurinic/apyrimidinic endonuclease, putative	0.0019	0.0024	0.0128
Plasmodium vivax	hypothetical protein, conserved	0.0039	0.0122	0.0286
Trypanosoma brucei	hypothetical protein, conserved	0.03	0.141	1
Entamoeba histolytica	zinc finger domain containing protein	0.0015	0.0007	0.0023
Loa Loa (eye worm)	hypothetical protein	0.0018	0.0019	0.0046
Onchocerca volvulus		0.0299	0.1406	0.3431
Echinococcus multilocularis	protein patched	0.0064	0.0248	0.0245
Echinococcus multilocularis	tumor protein p63	0.2041	1	1
Trichomonas vaginalis	glucosylceramidase, putative	0.0215	0.0993	0.243
Echinococcus granulosus	aldehyde dehydrogenase mitochondrial	0.0195	0.0895	0.0892
Trichomonas vaginalis	conserved hypothetical protein	0.0015	0.0007	0.0018
Giardia lamblia	Ser/Thr protein kinase	0.0015	0.0007	0.0832
Plasmodium vivax	E3 ubiquitin-protein ligase, putative	0.0015	0.0007	0.0004
Schistosoma mansoni	lamin	0.0027	0.0063	0.0085
Schistosoma mansoni	aldehyde dehydrogenase	0.0195	0.0895	0.1274
Echinococcus multilocularis	nuclear receptor 2DBD gamma	0.0015	0.0008	0.0004
Echinococcus multilocularis	Upstream activation factor subunit UAF30	0.0842	0.4086	0.4084
Leishmania major	4-coumarate:coa ligase-like protein	0.0036	0.0109	0.0729
Echinococcus multilocularis	aldehyde dehydrogenase, mitochondrial	0.0195	0.0895	0.0892
Echinococcus multilocularis	E3 ubiquitin protein ligase LRSAM1	0.0015	0.0007	0.0004
Echinococcus multilocularis	nuclear receptor subfamily 1 group D	0.0017	0.0017	0.0013
Echinococcus multilocularis	RING finger protein 185	0.0015	0.0007	0.0004
Echinococcus granulosus	FTZ F1 nuclear receptor protein	0.0032	0.0092	0.0089
Trichomonas vaginalis	conserved hypothetical protein	0.0015	0.0007	0.0018
Plasmodium vivax	SWIB/MDM2 domain-containing protein, putative	0.0842	0.4086	1
Loa Loa (eye worm)	hypothetical protein	0.0015	0.0007	0.0017
Onchocerca volvulus	Protein ultraspiracle homolog	0.0032	0.0092	0.0212
Giardia lamblia	Hypothetical protein	0.0015	0.0007	0.0832
Trypanosoma cruzi	UEV domain/Zinc finger, C3HC4 type (RING finger), putative	0.0015	0.0007	0.0011
Brugia malayi	Ets-domain containing protein	0.0052	0.0189	0.0462
Entamoeba histolytica	hypothetical protein	0.0015	0.0007	0.0023
Brugia malayi	Zinc finger protein 183 homolog	0.0016	0.0009	0.002
Brugia malayi	hypothetical protein	0.0128	0.0564	0.138
Loa Loa (eye worm)	hypothetical protein	0.03	0.141	0.3449
Echinococcus granulosus	survival motor neuron protein 1	0.0563	0.2711	0.2708
Loa Loa (eye worm)	hypothetical protein	0.048	0.2301	0.5631
Entamoeba histolytica	Activator 1 140 kDa subunit, putative	0.0015	0.0006	0.000004859
Brugia malayi	nuclear receptor NHR-88	0.0015	0.0008	0.0018
Loa Loa (eye worm)	hypothetical protein	0.0025	0.0057	0.0138
Leishmania major	isocitrate dehydrogenase [NADP], mitochondrial precursor, putative	0.0017	0.0016	0.0059
Schistosoma mansoni	DNA ligase IV	0.0015	0.0006	0.0003
Leishmania major	cytochrome p450-like protein	0.0025	0.0054	0.0337
Brugia malayi	RING zinc finger protein	0.0015	0.0007	0.0017
Giardia lamblia	Ribonuclease	0.0015	0.0007	0.0832
Brugia malayi	exodeoxyribonuclease III family protein	0.0019	0.0024	0.0057
Schistosoma mansoni	cellular tumor antigen P53	0.0299	0.1406	0.2004
Echinococcus multilocularis	neuropeptide s receptor	0.0496	0.2376	0.2373
Trichomonas vaginalis	replication factor C large subunit, putative	0.0015	0.0006	0.0014
Trypanosoma brucei	isocitrate dehydrogenase, putative	0.0017	0.0016	0.007
Trypanosoma cruzi	hypothetical protein, conserved	0.0015	0.0007	0.0011
Loa Loa (eye worm)	CYP4Cod1	0.0025	0.0054	0.0132
Loa Loa (eye worm)	nuclear Hormone Receptor family member	0.0032	0.0092	0.0225
Schistosoma mansoni	ap endonuclease	0.0019	0.0024	0.0029
Brugia malayi	photoreceptor-specific nuclear receptor	0.0032	0.0092	0.0225
Loa Loa (eye worm)	hypothetical protein	0.0015	0.0007	0.0017
Echinococcus granulosus	nuclear receptor 2DBD gamma	0.0015	0.0008	0.0004
Entamoeba histolytica	zinc finger domain containing protein	0.0015	0.0007	0.0023
Toxoplasma gondii	zinc finger, C3HC4 type (RING finger) domain-containing protein	0.0015	0.0007	0.0004
Entamoeba histolytica	zinc finger domain containing protein	0.0015	0.0007	0.0023
Trypanosoma cruzi	Zn-finger in Ran binding protein and others, putative	0.03	0.141	1
Brugia malayi	Ligand-binding domain of nuclear hormone receptor family protein	0.0032	0.0092	0.0225
Toxoplasma gondii	exonuclease III APE	0.0019	0.0024	0.0044
Echinococcus multilocularis	voltage gated potassium channel	0.0021	0.0037	0.0033
Schistosoma mansoni	histone-lysine n-methyltransferase setb1	0.0078	0.0315	0.0444
Trypanosoma cruzi	Zn-finger in Ran binding protein and others/FYVE zinc finger, putative	0.03	0.141	1
Echinococcus granulosus	Nuclear hormone receptor HR96	0.0015	0.0008	0.0004
Loa Loa (eye worm)	brahma associated protein	0.0842	0.4086	1
Echinococcus granulosus	Niemann Pick C1 protein	0.0214	0.0985	0.0982
Brugia malayi	Nuclear hormone receptor family member nhr-3	0.0032	0.0092	0.0225
Echinococcus granulosus	Protein patched homolog 1	0.0064	0.0248	0.0245
Mycobacterium tuberculosis	Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI)	0.0019	0.0024	0.0072
Echinococcus multilocularis	NADP dependent isocitrate dehydrogenase	0.0017	0.0016	0.0012
Brugia malayi	hypothetical protein	0.0015	0.0007	0.0017
Loa Loa (eye worm)	abnormal chemotaxis protein 14	0.0064	0.0248	0.0607
Toxoplasma gondii	ran binding protein	0.03	0.141	0.3441
Brugia malayi	O-Glycosyl hydrolase family 30 protein	0.0215	0.0993	0.2429
Onchocerca volvulus		0.03	0.141	0.3441
Trichomonas vaginalis	conserved hypothetical protein	0.0015	0.0007	0.0018
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0106	0.0258
Schistosoma mansoni	retinoic acid receptor RXR	0.0032	0.0092	0.0127
Trypanosoma brucei	Ankyrin repeats (3 copies)/Zinc finger, C3HC4 type (RING finger), putative	0.0015	0.0007	0.0011
Trichomonas vaginalis	conserved hypothetical protein	0.0015	0.0007	0.0018
Loa Loa (eye worm)	hypothetical protein	0.0015	0.0007	0.0017
Echinococcus granulosus	GPCR family 2	0.0046	0.0159	0.0155
Giardia lamblia	E3 ubiquitin ligase for Rad6p required for the ubiquitination of histone H2B	0.0015	0.0007	0.0832
Entamoeba histolytica	hypothetical protein	0.0036	0.011	0.1578
Giardia lamblia	Hypothetical protein	0.0015	0.0007	0.0832
Mycobacterium tuberculosis	Probable lipase LipE	0.0039	0.0122	0.0943
Schistosoma mansoni	smad1 5 8 and	0.0025	0.0056	0.0074
Plasmodium vivax	SET domain protein, putative	0.0063	0.0242	0.0579
Toxoplasma gondii	Bardet-Biedl syndrome 5, putative	0.0015	0.0007	0.0004
Trichomonas vaginalis	D-aminoacylase, putative	0.0039	0.0122	0.0299
Toxoplasma gondii	isocitrate dehydrogenase	0.0017	0.0016	0.0024
Schistosoma mansoni	family S12 unassigned peptidase (S12 family)	0.0039	0.0122	0.017
Trypanosoma brucei	Plus-3 domain/Zinc finger, C3HC4 type (RING finger), putative	0.0015	0.0007	0.0011
Loa Loa (eye worm)	hypothetical protein	0.0027	0.0065	0.0157
Brugia malayi	hypothetical protein	0.0314	0.1481	0.3623
Trypanosoma brucei	SNF2 family N-terminal domain/Ring finger domain containing protein, putative	0.0015	0.0007	0.0011
Plasmodium vivax	RING zinc finger protein, putative	0.0015	0.0007	0.0004
Toxoplasma gondii	hypothetical protein	0.0015	0.0007	0.0004
Brugia malayi	Nuclear hormone receptor family member nhr-41	0.0032	0.0092	0.0225
Echinococcus granulosus	geminin	0.0182	0.0828	0.0824
Onchocerca volvulus		0.0027	0.0063	0.0141
Echinococcus multilocularis	nuclear receptor 2DBD gamma	0.0032	0.0092	0.0089
Trichomonas vaginalis	D-aminoacylase, putative	0.0039	0.0122	0.0299
Brugia malayi	Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog	0.0021	0.0037	0.009
Plasmodium vivax	ataxin-2 like protein, putative	0.0025	0.0057	0.0126
Brugia malayi	Latrophilin receptor protein 2	0.0046	0.0159	0.0388
Schistosoma mansoni	TRABID protein (C64 family)	0.03	0.141	0.201
Echinococcus multilocularis	SWI:SNF matrix associated	0.0842	0.4086	0.4084
Echinococcus multilocularis	retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha	0.0015	0.0008	0.0004
Brugia malayi	Ets-domain containing protein	0.0052	0.0189	0.0462
Echinococcus granulosus	FTZ F1 alpha	0.0032	0.0092	0.0089
Echinococcus granulosus	cadherin EGF LAG seven pass G type receptor	0.0046	0.0159	0.0155
Plasmodium falciparum	E3 ubiquitin-protein ligase RNF5, putative	0.0015	0.0007	0.0004
Echinococcus multilocularis	bromodomain adjacent to zinc finger domain	0.0031	0.0085	0.0082
Brugia malayi	hypothetical protein	0.0036	0.011	0.0269
Loa Loa (eye worm)	cyclic-nucleotide gated cation channel	0.0015	0.0004	0.0008
Entamoeba histolytica	acyl-CoA synthetase, putative	0.0036	0.0109	0.1565
Brugia malayi	Neuralized family protein	0.0015	0.0007	0.0017
Onchocerca volvulus		0.0036	0.0109	0.0254
Mycobacterium ulcerans	fatty-acid-CoA ligase	0.0036	0.0109	0.1167
Loa Loa (eye worm)	hypothetical protein	0.0015	0.0008	0.0018
Mycobacterium ulcerans	aldehyde dehydrogenase	0.0195	0.0895	1
Trichomonas vaginalis	glucosylceramidase, putative	0.0141	0.0628	0.1537
Plasmodium vivax	acyl-CoA synthetase, putative	0.0027	0.0065	0.0144
Schistosoma mansoni	nuclear receptor nhr-48	0.0015	0.0008	0.0006
Trypanosoma brucei	cytochrome P450, putative	0.0025	0.0054	0.0347
Schistosoma mansoni	FTZ-F1 nuclear receptor-like protein	0.0032	0.0092	0.0127
Toxoplasma gondii	LsmAD domain-containing protein	0.0025	0.0057	0.0126
Schistosoma mansoni	thyroid hormone receptor	0.0032	0.0092	0.0127
Giardia lamblia	Protein 21.1	0.0015	0.0007	0.0832
Schistosoma mansoni	coup transcription factor	0.0032	0.0092	0.0127
Brugia malayi	Zn-finger in Ran binding protein and others containing protein	0.03	0.141	0.3449
Echinococcus multilocularis	NADP dependent isocitrate dehydrogenase	0.0017	0.0016	0.0012
Echinococcus multilocularis	Nuclear hormone receptor HR96	0.0015	0.0008	0.0004
Schistosoma mansoni	steroid hormone receptor ad4bp	0.0032	0.0092	0.0127
Trichomonas vaginalis	conserved hypothetical protein	0.0015	0.0007	0.0018
Brugia malayi	nuclear hormone receptor	0.0015	0.0008	0.0018
Trichomonas vaginalis	voltage and ligand gated potassium channel, putative	0.0015	0.0004	0.0009
Echinococcus granulosus	zinc finger protein Ran binding	0.03	0.141	0.1406
Echinococcus multilocularis	RING finger and transmembrane domain containing protein	0.0015	0.0007	0.0004
Trypanosoma brucei	predicted zinc finger protein	0.0015	0.0007	0.0011
Schistosoma mansoni	hypothetical protein	0.03	0.141	0.201
Loa Loa (eye worm)	hypothetical protein	0.0036	0.0109	0.0267
Schistosoma mansoni	zinc finger protein	0.0015	0.0008	0.0006
Loa Loa (eye worm)	hypothetical protein	0.0015	0.0008	0.0018
Mycobacterium tuberculosis	Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase)	0.0036	0.0109	0.083
Brugia malayi	Smad1	0.0025	0.0056	0.0135
Brugia malayi	tailless protein	0.0015	0.0008	0.0018
Echinococcus multilocularis	E3 ubiquitin protein ligase mib1	0.0015	0.0007	0.0004
Echinococcus multilocularis	FTZ F1 alpha	0.0032	0.0092	0.0089
Loa Loa (eye worm)	latrophilin receptor protein 2	0.0046	0.0159	0.0388
Loa Loa (eye worm)	hypothetical protein	0.0027	0.0065	0.0157
Leishmania major	hypothetical protein, conserved	0.03	0.141	1
Trypanosoma cruzi	UEV domain/Zinc finger, C3HC4 type (RING finger), putative	0.0015	0.0007	0.0011
Trichomonas vaginalis	conserved hypothetical protein	0.0015	0.0007	0.0018
Loa Loa (eye worm)	hypothetical protein	0.0026	0.0061	0.0148
Trypanosoma cruzi	Zinc finger, C3HC4 type (RING finger)/EF-hand domain pair, putative	0.0015	0.0007	0.0011
Trichomonas vaginalis	conserved hypothetical protein	0.0015	0.0007	0.0018
Echinococcus multilocularis	FTZ F1 nuclear receptor protein	0.0032	0.0092	0.0089
Mycobacterium tuberculosis	Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase)	0.0025	0.0057	0.037
Brugia malayi	beta-lactamase family protein	0.0039	0.0122	0.0298
Loa Loa (eye worm)	hypothetical protein	0.0015	0.0008	0.0018
Loa Loa (eye worm)	hypothetical protein	0.0149	0.0669	0.1636
Toxoplasma gondii	DNA topoisomerase domain-containing protein	0.0842	0.4086	1
Trichomonas vaginalis	glucosylceramidase, putative	0.0215	0.0993	0.243
Mycobacterium ulcerans	acyl-CoA synthetase	0.0036	0.0109	0.1167
Giardia lamblia	Hypothetical protein	0.0015	0.0007	0.0832
Schistosoma mansoni	Smad4	0.0025	0.0056	0.0074
Mycobacterium ulcerans	aldehyde dehydrogenase	0.0195	0.0895	1
Entamoeba histolytica	acyl-coA synthetase, putative	0.0036	0.0109	0.1565
Trypanosoma cruzi	Plus-3 domain/Zinc finger, C3HC4 type (RING finger), putative	0.0015	0.0007	0.0011
Echinococcus granulosus	Nuclear hormone receptor HR96	0.0015	0.0008	0.0004
Echinococcus granulosus	replication factor c subunit 1	0.0015	0.0006	0.0002
Trypanosoma brucei	Zinc finger, C3HC4 type (RING finger), putative	0.0015	0.0007	0.0011
Mycobacterium leprae	Probable lipase LipE	0.0039	0.0122	1
Mycobacterium ulcerans	long-chain fatty-acid CoA ligase	0.0036	0.0109	0.1167
Brugia malayi	Nuclear hormone receptor E75	0.0015	0.0008	0.0018
Leishmania major	apurinic/apyrimidinic endonuclease-redox protein	0.0019	0.0024	0.0117
Echinococcus multilocularis	musashi	0.0027	0.0063	0.006
Schistosoma mansoni	nuclear receptor	0.0015	0.0008	0.0006
Giardia lamblia	Protein 21.1	0.0015	0.0007	0.0832
Toxoplasma gondii	hypothetical protein	0.0015	0.0007	0.0004
Brugia malayi	SWIB/MDM2 domain containing protein	0.0842	0.4086	1
Echinococcus granulosus	histone lysine N methyltransferase MLL3	0.0017	0.0018	0.0014
Loa Loa (eye worm)	hypothetical protein	0.0015	0.0006	0.0013
Loa Loa (eye worm)	cytochrome P450 family protein	0.0025	0.0054	0.0132
Echinococcus granulosus	nuclear receptor 2DBD gamma	0.0032	0.0092	0.0089
Plasmodium falciparum	SWIB/MDM2 domain-containing protein	0.0842	0.4086	1
Mycobacterium tuberculosis	Probable hydrolase	0.0039	0.0122	0.0943
Loa Loa (eye worm)	hypothetical protein	0.0015	0.0007	0.0017
Onchocerca volvulus	RING finger protein 141 homolog	0.0015	0.0007	0.0004
Brugia malayi	Nuclear hormone receptor family member nhr-19	0.0032	0.0092	0.0225
Echinococcus multilocularis	ring and YY1 binding protein	0.03	0.141	0.1406
Trichomonas vaginalis	conserved hypothetical protein	0.0015	0.0007	0.0018
Brugia malayi	Nuclear hormone receptor family member nhr-19	0.0032	0.0092	0.0225
Giardia lamblia	Protein 21.1	0.0015	0.0007	0.0832
Echinococcus granulosus	ring and YY1 binding protein	0.03	0.141	0.1406
Echinococcus granulosus	potassium voltage gated channel subfamily H	0.0021	0.0037	0.0033
Echinococcus granulosus	bromodomain adjacent to zinc finger domain	0.0055	0.0204	0.02
Plasmodium falciparum	zinc finger protein, putative	0.0015	0.0007	0.0004
Onchocerca volvulus		0.0015	0.0007	0.0004
Loa Loa (eye worm)	hypothetical protein	0.0032	0.0092	0.0225
Wolbachia endosymbiont of Brugia malayi	exonuclease III	0.0019	0.0024	1
Echinococcus multilocularis	muscleblind protein 1	0.048	0.2301	0.2298
Schistosoma mansoni	hypothetical protein	0.0046	0.0159	0.0222
Trypanosoma brucei	DNA repair protein, putative	0.0015	0.0007	0.0011
Trypanosoma cruzi	mitochondrial RNA binding complex 1 subunit, putative	0.03	0.141	1
Schistosoma mansoni	hypothetical protein	0.0046	0.0159	0.0222
Brugia malayi	hypothetical protein	0.0025	0.0057	0.0138
Brugia malayi	nuclear receptor subfamily 1, group D, member 1, putative	0.0015	0.0008	0.0018
Mycobacterium ulcerans	hypothetical protein	0.0036	0.0109	0.1167
Schistosoma mansoni	methyl-cpg binding protein mbd	0.0015	0.0005	0.0002
Leishmania major	4-coumarate:coa ligase-like protein	0.0036	0.0109	0.0729
Mycobacterium ulcerans	hypothetical protein	0.0039	0.0122	0.1311
Trypanosoma cruzi	hypothetical protein, conserved	0.0039	0.0122	0.083
Entamoeba histolytica	zinc finger domain containing protein	0.0015	0.0007	0.0023
Schistosoma mansoni	ap endonuclease	0.0019	0.0024	0.0029
Echinococcus multilocularis	lamin	0.0027	0.0063	0.006
Trichomonas vaginalis	conserved hypothetical protein	0.0015	0.0006	0.0014
Loa Loa (eye worm)	nuclear hormone receptor-like 1	0.0017	0.0017	0.004
Trichomonas vaginalis	conserved hypothetical protein	0.0015	0.0007	0.0018
Trichomonas vaginalis	voltage and ligand gated potassium channel, putative	0.0069	0.0271	0.0662
Trichomonas vaginalis	glucosylceramidase, putative	0.0215	0.0993	0.243
Trichomonas vaginalis	glucosylceramidase, putative	0.0141	0.0628	0.1537
Echinococcus granulosus	E3 ubiquitin protein ligase Bre1	0.0015	0.0007	0.0004
Trichomonas vaginalis	conserved hypothetical protein	0.0015	0.0007	0.0018
Brugia malayi	nuclear receptor NHR-67	0.0015	0.0008	0.0018
Loa Loa (eye worm)	hypothetical protein	0.0039	0.0122	0.0298
Echinococcus multilocularis	beta LACTamase domain containing family member	0.0039	0.0122	0.0119
Brugia malayi	Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative	0.0039	0.0122	0.0298
Trypanosoma cruzi	mitochondrial RNA binding complex 1 subunit, putative	0.03	0.141	1
Loa Loa (eye worm)	hypothetical protein	0.0017	0.0017	0.004
Schistosoma mansoni	RNA binding protein	0.03	0.141	0.201
Schistosoma mansoni	hypothetical protein	0.0036	0.011	0.0152
Echinococcus granulosus	SWI:SNF matrix associated	0.0842	0.4086	0.4084
Brugia malayi	Corticotropin releasing factor receptor 2 precursor, putative	0.0145	0.0649	0.1588
Echinococcus granulosus	RING finger protein 185	0.0015	0.0007	0.0004
Brugia malayi	hypothetical protein	0.0015	0.0007	0.0017
Mycobacterium ulcerans	exodeoxyribonuclease III protein XthA	0.0019	0.0024	0.0202
Entamoeba histolytica	hypothetical protein	0.0036	0.011	0.1578
Trypanosoma brucei	UEV domain/Zinc finger, C3HC4 type (RING finger), putative	0.0015	0.0007	0.0011
Echinococcus multilocularis	DNA (apurinic or apyrimidinic site) lyase	0.0019	0.0024	0.002
Echinococcus multilocularis	sterol regulatory element binding protein	0.0064	0.0248	0.0245
Schistosoma mansoni	mind bomb	0.0015	0.0007	0.0005
Loa Loa (eye worm)	MH2 domain-containing protein	0.0025	0.0056	0.0135
Brugia malayi	Hypothetical RING finger protein C16C10.7 in chromosome III	0.0015	0.0007	0.0017
Brugia malayi	Nuclear hormone receptor-like 1	0.0032	0.0092	0.0225
Brugia malayi	MH1 domain containing protein	0.0025	0.0056	0.0135
Plasmodium falciparum	acyl-CoA synthetase	0.0027	0.0065	0.0144
Echinococcus granulosus	Nuclear hormone receptor family member nhr 41	0.0032	0.0092	0.0089
Schistosoma mansoni	chromosome transmission fidelity factor	0.0015	0.0006	0.0003
Echinococcus granulosus	TGF beta signal transducer SmadC	0.0025	0.0056	0.0052
Onchocerca volvulus		0.0063	0.0242	0.0579
Trypanosoma brucei	Zinc finger, C3HC4 type (RING finger), putative	0.0015	0.0007	0.0011
Toxoplasma gondii	ATPase, AAA family protein	0.0015	0.0006	0.0000007898
Echinococcus granulosus	NADP dependent isocitrate dehydrogenase	0.0017	0.0016	0.0012
Leishmania major	hypothetical protein, conserved	0.03	0.141	1
Echinococcus granulosus	GA binding protein alpha chain	0.0052	0.0189	0.0186
Schistosoma mansoni	histone-lysine n-methyltransferase suv9	0.0063	0.0242	0.034
Toxoplasma gondii	SWIB/MDM2 domain-containing protein	0.0842	0.4086	1
Echinococcus multilocularis	ring finger protein 113a	0.0016	0.0009	0.0005
Brugia malayi	hypothetical protein	0.0563	0.2711	0.6635
Trypanosoma cruzi	apurinic/apyrimidinic endonuclease, putative	0.0019	0.0024	0.0128
Trichomonas vaginalis	conserved hypothetical protein	0.0015	0.0007	0.0018
Trichomonas vaginalis	ap endonuclease, putative	0.0019	0.0024	0.0058
Echinococcus multilocularis	Nuclear hormone receptor HR96	0.0015	0.0008	0.0004
Brugia malayi	Nuclear hormone receptor family member nhr-14	0.0032	0.0092	0.0225
Giardia lamblia	Protein 21.1	0.0015	0.0007	0.0832
Schistosoma mansoni	zinc finger protein	0.03	0.141	0.201
Echinococcus multilocularis	zinc finger protein Ran binding	0.03	0.141	0.1406
Mycobacterium ulcerans	fatty-acid-CoA ligase	0.0027	0.0065	0.0662
Loa Loa (eye worm)	hypothetical protein	0.0015	0.0007	0.0017
Giardia lamblia	Protein 21.1	0.0015	0.0007	0.0832
Echinococcus granulosus	E3 ubiquitin protein ligase MYLIP	0.0015	0.0007	0.0004
Brugia malayi	Niemann-Pick C1 protein precursor	0.0149	0.0669	0.1636
Entamoeba histolytica	zinc finger domain containing protein	0.0015	0.0007	0.0023
Onchocerca volvulus		0.0115	0.0499	0.1209
Echinococcus multilocularis	isocitrate dehydrogenase	0.0017	0.0016	0.0012
Trichomonas vaginalis	glucosylceramidase, putative	0.0141	0.0628	0.1537
Brugia malayi	cytoplasmic intermediate filament protein	0.0014	0.0002	0.0005
Giardia lamblia	Protein 21.1	0.0015	0.0007	0.0832
Echinococcus multilocularis	geminin	0.0182	0.0828	0.0824

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

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External resources for this compound

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Bibliographic References

No literature references available for this target.

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Detailed information for compound 731166