Detailed information for compound 771760

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 446.538 | Formula: C27H30N2O4
  • H donors: 1 H acceptors: 3 LogP: 4.26 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: COC(=O)c1ccc(cc1)C1C2=C(O)CC(CC2=Nc2c(N1C(=O)C(C)C)cccc2)(C)C
  • InChi: 1S/C27H30N2O4/c1-16(2)25(31)29-21-9-7-6-8-19(21)28-20-14-27(3,4)15-22(30)23(20)24(29)17-10-12-18(13-11-17)26(32)33-5/h6-13,16,24,30H,14-15H2,1-5H3
  • InChiKey: SFMNJJGEYIVAIA-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0058 0.0505 0.0503
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0021 0.0114 0.0163
Brugia malayi AMP-binding enzyme family protein 0.0021 0.0114 0.0163
Echinococcus granulosus survival motor neuron protein 1 0.0256 0.2633 0.2633
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0114 0.0187
Echinococcus granulosus dnaJ subfamily B 0.04 0.4174 0.4174
Schistosoma mansoni zinc finger protein 0.0027 0.018 0.018
Plasmodium vivax endonuclease/exonuclease/phosphatase domain containing protein 0.0011 0.0011 0.0032
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0072 0.0656 0.1022
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0056 0.0493 0.112
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0027 0.018 0.018
Giardia lamblia Glutamate synthase 0.0022 0.0122 0.0399
Mycobacterium ulcerans citrate lyase beta subunit, CitE_2 0.0048 0.0399 0.0669
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0021 0.0114 0.0187
Onchocerca volvulus 0.0022 0.0122 0.0153
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0021 0.0114 0.0163
Trypanosoma cruzi DNA damage repair protein, putative 0.0019 0.0093 0.0208
Mycobacterium ulcerans esterase/lipase LipP 0.0078 0.0727 0.1222
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0027 0.018 0.0177
Toxoplasma gondii selenide, water dikinase 0.0022 0.0122 0.0491
Loa Loa (eye worm) hypothetical protein 0.009 0.0855 0.0852
Giardia lamblia DINP protein human, muc B family 0.0061 0.0547 0.1822
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0082 0.0767 0.0767
Echinococcus multilocularis sterol regulatory element binding protein 0.0046 0.0379 0.0379
Echinococcus granulosus CCR4 NOT transcription complex subunit 6 0.0011 0.0011 0.0011
Toxoplasma gondii HEAT repeat-containing protein 0.0088 0.0836 0.344
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0058 0.0505 0.0503
Trichomonas vaginalis esterase, putative 0.0078 0.0727 0.0933
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0138 0.1368 0.1368
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0058 0.0505 0.0739
Echinococcus multilocularis protein dispatched 1 0.0052 0.0448 0.0448
Schistosoma mansoni acetyl-CoA synthetase 0.0021 0.0114 0.0114
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0022 0.0122 0.0491
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0022 0.0122 0.0276
Mycobacterium tuberculosis Putative ferredoxin reductase 0.054 0.5672 0.8977
Mycobacterium leprae PROBABLE NADPH:ADRENODOXIN OXIDOREDUCTASE FPRB (ADRENODOXIN REDUCTASE) (AR) (FERREDOXIN-NADP(+) REDUCTASE) 0.0022 0.0122 0.0188
Brugia malayi Nuclear hormone receptor-like 1 0.003 0.0215 0.0311
Trypanosoma cruzi Inositol phosphosphingolipids phospholipase C 0.0011 0.0011 0.0018
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0078 0.0727 0.1064
Leishmania major GTP-binding protein, putative 0.0041 0.033 0.0741
Schistosoma mansoni hypothetical protein 0.0044 0.0361 0.0361
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0114 0.0187
Entamoeba histolytica acyl-coA synthetase, putative 0.0072 0.0656 0.2187
Loa Loa (eye worm) hypothetical protein 0.0072 0.0656 0.0653
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0153 0.0346
Trypanosoma cruzi hypothetical protein, conserved 0.0414 0.432 1
Onchocerca volvulus Putative neutral sphingomyelinase 0.0011 0.0011 0.001
Schistosoma mansoni glutamate synthase 0.0022 0.0122 0.0122
Trypanosoma brucei chrX additional, unordered contigs 0.0019 0.0093 0.0208
Brugia malayi N-terminal motif family protein 0.02 0.2027 0.2975
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0058 0.0505 0.0739
Trypanosoma brucei unspecified product 0.0042 0.0342 0.0786
Echinococcus multilocularis JmjC domain containing protein 4 0.0018 0.0083 0.0083
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0031 0.0222 0.0222
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0022 0.0122 0.0122
Schistosoma mansoni DNA polymerase eta 0.009 0.0855 0.0855
Loa Loa (eye worm) hypothetical protein 0.0025 0.0153 0.015
Leishmania major hypothetical protein, conserved 0.0018 0.0083 0.0167
Schistosoma mansoni tar DNA-binding protein 0.0124 0.1212 0.1212
Entamoeba histolytica hypothetical protein 0.007 0.0637 0.2126
Plasmodium falciparum thioredoxin reductase 0.0237 0.2424 1
Schistosoma mansoni RAR-like nuclear receptor 0.0058 0.0505 0.0505
Schistosoma mansoni hypothetical protein 0.0044 0.0361 0.0361
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0058 0.0505 0.0503
Trypanosoma brucei hypothetical protein, conserved 0.0414 0.432 1
Treponema pallidum NADH oxidase 0.0082 0.0767 0.2562
Loa Loa (eye worm) hypothetical protein 0.0027 0.018 0.0177
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0022 0.0122 0.0276
Toxoplasma gondii aldehyde dehydrogenase 0.0119 0.1169 0.4814
Mycobacterium tuberculosis Probable reductase 0.054 0.5672 0.8977
Trichomonas vaginalis replication factor C large subunit, putative 0.0011 0.0003 0.00000041586
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0072 0.0657 0.0843
Plasmodium falciparum glutathione reductase 0.0237 0.2424 1
Loa Loa (eye worm) hypothetical protein 0.0053 0.0462 0.0459
Trypanosoma brucei DNA polymerase kappa, putative 0.0061 0.0547 0.1259
Echinococcus granulosus thyroid hormone receptor alpha 0.0027 0.018 0.018
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0058 0.0505 0.0505
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0011 0.0011 0.0032
Trichomonas vaginalis type IV inositol 5-phosphatase, putative 0.0011 0.0011 0.001
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0114 0.0187
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0027 0.018 0.018
Echinococcus granulosus jumonji domain containing 1A 0.0018 0.0083 0.0083
Brugia malayi latrophilin 2 splice variant baaae 0.0067 0.061 0.0892
Schistosoma mansoni ap endonuclease 0.0056 0.0493 0.0493
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0031 0.0222 0.0222
Brugia malayi Calcitonin receptor-like protein seb-1 0.0098 0.0943 0.1382
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0022 0.0122 0.0399
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0011 0.0011 0.0012
Echinococcus multilocularis replication factor c subunit 1 0.0011 0.0003 0.0003
Mycobacterium tuberculosis Conserved protein 0.0048 0.0399 0.0616
Loa Loa (eye worm) hypothetical protein 0.0053 0.0462 0.0459
Echinococcus multilocularis neutral sphingomyelinase 0.0011 0.0011 0.0011
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0878 0.9298 0.9298
Trichomonas vaginalis D-aminoacylase, putative 0.0078 0.0727 0.0933
Loa Loa (eye worm) jmjC domain-containing protein 0.0018 0.0083 0.008
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0093 0.0208
Brugia malayi conserved hypotetical protein 0.0027 0.018 0.026
Onchocerca volvulus 0.0735 0.776 1
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0058 0.0505 0.0739
Mycobacterium ulcerans dehydrogenase 0.0022 0.0122 0.0201
Trypanosoma cruzi pantothenate kinase subunit, putative 0.0014 0.0042 0.0091
Echinococcus granulosus JmjC domain containing protein 4 0.0018 0.0083 0.0083
Schistosoma mansoni hypothetical protein 0.0044 0.0361 0.0361
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0022 0.0122 0.0399
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0056 0.0493 0.1644
Schistosoma mansoni hypothetical protein 0.036 0.3743 0.3743
Mycobacterium ulcerans glutamate synthase subunit beta 0.0022 0.0122 0.0201
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0022 0.0122 0.0258
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0056 0.0493 0.0493
Echinococcus granulosus nuclear receptor nhr 48 0.0027 0.018 0.018
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0021 0.0114 0.0187
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0058 0.0505 0.0505
Loa Loa (eye worm) MH2 domain-containing protein 0.0115 0.1125 0.1122
Mycobacterium tuberculosis Conserved hypothetical protein 0.0061 0.0547 0.0849
Brugia malayi glutathione reductase 0.0237 0.2424 0.3559
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0012 0.0013 0.0013
Onchocerca volvulus 0.0027 0.018 0.0228
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0082 0.0767 1
Schistosoma mansoni hypothetical protein 0.0031 0.0222 0.0222
Loa Loa (eye worm) hypothetical protein 0.0053 0.0462 0.0459
Echinococcus granulosus thioredoxin glutathione reductase 0.0237 0.2424 0.2424
Loa Loa (eye worm) glutathione reductase 0.0237 0.2424 0.2422
Trypanosoma cruzi DNA polymerase eta, putative 0.009 0.0855 0.1973
Plasmodium vivax JmjC domain containing protein 0.0018 0.0083 0.033
Echinococcus granulosus importin subunit beta 1 0.0088 0.0836 0.0836
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0011 0.0011 0.0018
Schistosoma mansoni phd/f-box containing protein 0.0018 0.0083 0.0083
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0041 0.033 0.1352
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0061 0.0547 0.0547
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0022 0.0122 0.0122
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0058 0.0505 0.0739
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0058 0.0505 0.0505
Loa Loa (eye worm) hypothetical protein 0.0019 0.0093 0.009
Trypanosoma cruzi trypanothione reductase, putative 0.0082 0.0767 0.177
Entamoeba histolytica Ran family GTPase 0.0041 0.033 0.1097
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0058 0.0505 0.0505
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0011 0.0011 0.0011
Loa Loa (eye worm) latrophilin receptor protein 2 0.0031 0.0222 0.0219
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0018 0.0083 0.0083
Leishmania major NADH dehydrogenase, putative 0.0022 0.0122 0.0258
Onchocerca volvulus 0.0078 0.0727 0.0933
Echinococcus granulosus FTZ F1 alpha 0.0058 0.0505 0.0505
Schistosoma mansoni hypothetical protein 0.0022 0.0122 0.0122
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0056 0.0493 0.2026
Brugia malayi ecdysone receptor 0.0027 0.018 0.026
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0058 0.0505 0.0503
Echinococcus granulosus translational activator gcn1 0.0017 0.0068 0.0068
Brugia malayi AMP-binding enzyme family protein 0.0072 0.0656 0.0959
Trichomonas vaginalis set domain proteins, putative 0.0735 0.776 1
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0056 0.0493 0.6417
Echinococcus granulosus Niemann Pick C1 protein 0.0152 0.1521 0.1521
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0022 0.0122 0.0399
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0011 0.0011 0.0012
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0041 0.033 0.033
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0048 0.0403 0.0926
Schistosoma mansoni hypothetical protein 0.0031 0.0222 0.0222
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0018 0.0083 0.033
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0021 0.0114 0.0257
Entamoeba histolytica sphingomyelinase C precursor, putative 0.0011 0.0011 0.0026
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0022 0.0122 0.0276
Loa Loa (eye worm) hypothetical protein 0.0021 0.0114 0.0111
Plasmodium falciparum DNase I-like protein, putative 0.0011 0.0011 0.0032
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0022 0.0122 0.0491
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.003 0.0215 0.0215
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0021 0.0114 0.0458
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0011 0.0011 0.0008
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0041 0.033 0.1352
Mycobacterium ulcerans UDP-galactopyranose mutase Glf 0.0563 0.5926 1
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0093 0.0886 0.0886
Leishmania major hypothetical protein, conserved 0.0022 0.0122 0.0258
Brugia malayi CCR4 0.0012 0.0013 0.0015
Entamoeba histolytica endonuclease/exonuclease/phosphatase domain containing protein 0.0011 0.0011 0.0026
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0082 0.0767 0.129
Schistosoma mansoni hypothetical protein 0.007 0.0637 0.0637
Loa Loa (eye worm) hypothetical protein 0.0088 0.0836 0.0833
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0022 0.0122 0.0153
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0082 0.0767 0.177
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.019 0.0187
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0011 0.0011 0.0032
Entamoeba histolytica inositol polyphosphate-5-phosphatase, putative 0.0011 0.0011 0.0026
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0011 0.0011 0.0026
Plasmodium vivax exodeoxyribonuclease III, putative 0.0011 0.0011 0.0032
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0078 0.0727 0.1222
Mycobacterium tuberculosis Probable NADPH:adrenodoxin oxidoreductase FprB (adrenodoxin reductase) (AR) (ferredoxin-NADP(+) reductase) 0.0022 0.0122 0.0176
Trypanosoma cruzi RNA-editing complex protein MP100, putative 0.0011 0.0011 0.0018
Loa Loa (eye worm) hypothetical protein 0.0078 0.0727 0.0724
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.003 0.0215 0.0212
Schistosoma mansoni glutamate synthase 0.0022 0.0122 0.0122
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0061 0.0547 0.0547
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0022 0.0122 0.0491
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0114 0.0187
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0021 0.0114 0.0163
Plasmodium falciparum carbon catabolite repressor protein 4, putative 0.0011 0.0011 0.0032
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0098 0.0943 0.1382
Entamoeba histolytica thioredoxin reductase, putative 0.0022 0.0122 0.0399
Toxoplasma gondii ATPase, AAA family protein 0.0011 0.0003 0.0000013324
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0119 0.1169 0.2687
Trypanosoma brucei DNA polymerase kappa, putative 0.0061 0.0547 0.1259
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0022 0.0122 0.0399
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0021 0.0114 0.0163
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0141 0.1402 0.2216
Trichomonas vaginalis mercuric reductase, putative 0.0082 0.0767 0.0985
Brugia malayi hypothetical protein 0.0025 0.0153 0.022
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0072 0.0656 0.1102
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0027 0.018 0.018
Schistosoma mansoni tar DNA-binding protein 0.0124 0.1212 0.1212
Leishmania major importin beta-1 subunit, putative 0.0072 0.0657 0.1499
Mycobacterium tuberculosis Probable oxidoreductase 0.06 0.6317 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0061 0.0547 0.1259
Mycobacterium tuberculosis Conserved hypothetical protein 0.018 0.1814 0.286
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0114 0.0187
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0018 0.0083 0.0114
Echinococcus multilocularis FTZ F1 alpha 0.0058 0.0505 0.0505
Echinococcus multilocularis lysine specific demethylase 5A 0.0068 0.0616 0.0616
Mycobacterium ulcerans hypothetical protein 0.018 0.1814 0.3058
Brugia malayi kap beta 3 protein 0.0017 0.0068 0.0095
Mycobacterium tuberculosis Possible penicillin-binding protein 0.05 0.5241 0.8294
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0141 0.1402 0.2206
Leishmania major DNA polymerase kappa, putative 0.0019 0.0093 0.019
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0022 0.0122 0.0122
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0289 0.2987 0.3847
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0141 0.1402 0.2362
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0022 0.0122 0.0153
Trypanosoma brucei DNA polymerase IV, putative 0.0061 0.0547 0.1259
Schistosoma mansoni thyroid hormone receptor 0.0058 0.0505 0.0505
Trichomonas vaginalis glutathione reductase, putative 0.0082 0.0767 0.0985
Loa Loa (eye worm) hypothetical protein 0.0107 0.1031 0.1028
Brugia malayi jmjC domain containing protein 0.0068 0.0616 0.0902
Mycobacterium tuberculosis Conserved protein 0.0078 0.0727 0.1135
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0021 0.0114 0.0176
Trichomonas vaginalis Phospholipase C precursor, putative 0.0011 0.0011 0.001
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0108 0.1049 0.1049
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0056 0.0493 0.2026
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0082 0.0767 0.3157
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0138 0.1368 0.1368
Echinococcus granulosus dna polymerase eta 0.009 0.0855 0.0855
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0022 0.0122 0.0119
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0138 0.1368 0.1365
Mycobacterium tuberculosis Probable dehydrogenase 0.054 0.5672 0.8977
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.06 0.6317 1
Brugia malayi jmjC domain containing protein 0.0018 0.0083 0.0117
Mycobacterium ulcerans monoxygenase 0.0022 0.0122 0.0201
Brugia malayi TAR-binding protein 0.0124 0.1212 0.1778
Echinococcus granulosus synaptojanin 1 0.0011 0.0011 0.0011
Trichomonas vaginalis hypothetical protein 0.0017 0.0068 0.0084
Loa Loa (eye worm) hypothetical protein 0.0053 0.0462 0.0459
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0082 0.0767 0.177
Brugia malayi Nuclear hormone receptor E75 0.0027 0.018 0.026
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0018 0.0083 0.0185
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0161 0.1619 0.3732
Trichomonas vaginalis antibiotic synthetase, putative 0.0021 0.0114 0.0143
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0082 0.0767 1
Echinococcus granulosus lysine specific demethylase 5A 0.007 0.0633 0.0633
Schistosoma mansoni patched 1 0.0046 0.0379 0.0379
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.007 0.0637 0.0637
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0078 0.0727 0.0727
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0289 0.2987 0.3847
Mycobacterium tuberculosis Probable lipase LipD 0.0078 0.0727 0.1135
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0027 0.018 0.018
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0022 0.0122 0.0276
Schistosoma mansoni DNA ligase IV 0.0011 0.0003 0.0003
Brugia malayi Niemann-Pick C1 protein precursor 0.0107 0.1031 0.1512
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0061 0.0547 0.0547
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0011 0.0011 0.0012
Loa Loa (eye worm) hypothetical protein 0.0058 0.0505 0.0503
Echinococcus granulosus histone lysine methyltransferase setb 0.0093 0.0886 0.0886
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0341 0.3544 0.8204
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0119 0.1169 0.1836
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0051 0.043 0.0665
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0058 0.0505 0.0505
Schistosoma mansoni topbp1 0.0011 0.0003 0.0003
Mycobacterium tuberculosis Probable hydrolase 0.0078 0.0727 0.1135
Loa Loa (eye worm) jmjC domain-containing protein 0.0018 0.0083 0.008
Loa Loa (eye worm) hypothetical protein 0.0085 0.0802 0.0799
Schistosoma mansoni nocturnin 0.0011 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0031 0.0222 0.0219
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0082 0.0767 0.3157
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0119 0.1169 0.1169
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.02 0.2027 0.2609
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0021 0.0114 0.0163
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0289 0.2987 0.3847
Mycobacterium tuberculosis Possible dehydrogenase/reductase 0.0022 0.0122 0.0176
Echinococcus granulosus beta LACTamase domain containing family member 0.0078 0.0727 0.0727
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0078 0.0727 0.1135
Leishmania major acetyl-CoA synthetase, putative 0.0021 0.0114 0.0239
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0021 0.0114 0.0111
Schistosoma mansoni neutral sphingomyelinase 0.0011 0.0011 0.0011
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0237 0.2424 0.3827
Brugia malayi Importin beta-1 subunit 0.0088 0.0836 0.1225
Loa Loa (eye worm) hypothetical protein 0.0067 0.061 0.0607
Plasmodium vivax hypothetical protein, conserved 0.0078 0.0727 0.2989
Loa Loa (eye worm) hypothetical protein 0.0027 0.018 0.0177
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0022 0.0122 0.0276
Loa Loa (eye worm) hypothetical protein 0.0098 0.0943 0.094
Entamoeba histolytica inositol polyphosphate 5-phosphatase, putative 0.0011 0.0011 0.0026
Plasmodium falciparum acyl-CoA synthetase 0.0053 0.0462 0.1895
Plasmodium falciparum DNA repair protein REV1, putative 0.0019 0.0093 0.0371
Leishmania major hypothetical protein, conserved 0.0017 0.0068 0.0132
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0082 0.0767 0.177
Echinococcus granulosus sterol regulatory element binding protein 0.0046 0.0379 0.0379
Schistosoma mansoni synaptojanin 0.0011 0.0011 0.0011
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0011 0.0003 0.00000041586
Mycobacterium ulcerans hypothetical protein 0.0078 0.0727 0.1222
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0022 0.0122 0.0122
Leishmania major 4-coumarate:coa ligase-like protein 0.0072 0.0656 0.1496
Loa Loa (eye worm) hypothetical protein 0.003 0.0215 0.0212
Treponema pallidum oxidoreductase 0.0022 0.0122 0.0399
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0072 0.0656 0.1102
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0011 0.0011 0.0018
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0021 0.0114 0.0257
Brugia malayi beta-lactamase family protein 0.0078 0.0727 0.1064
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0011 0.0011 0.0026
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0021 0.0114 0.0163
Brugia malayi Pre-SET motif family protein 0.0645 0.6805 1
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0041 0.033 0.0481
Onchocerca volvulus 0.0021 0.0114 0.0143
Trypanosoma brucei DNA polymerase kappa, putative 0.0061 0.0547 0.1259
Echinococcus multilocularis dnaJ subfamily B 0.04 0.4174 0.4174
Mycobacterium ulcerans ferredoxin reductase 0.0022 0.0122 0.0201
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0022 0.0122 0.0153
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0058 0.0505 0.0739
Leishmania major hypothetical protein, conserved 0.0022 0.0122 0.0258
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0082 0.0767 0.3157
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0161 0.1619 0.3743
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0048 0.0399 0.0917
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0114 0.0187
Schistosoma mansoni hypothetical protein 0.0944 1 1
Schistosoma mansoni nuclear receptor nhr-48 0.0027 0.018 0.018
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0058 0.0505 0.0739
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0021 0.0114 0.0257
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0011 0.0011 0.0026
Leishmania major hypothetical protein, conserved 0.0025 0.0153 0.0329
Schistosoma mansoni retinoid-x-receptor (RXR) 0.003 0.0215 0.0215
Schistosoma mansoni protein phosphatase 2C 0.0018 0.0083 0.0083
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0011 0.0011 0.0008
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0058 0.0505 0.0648
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0289 0.2987 1
Trypanosoma cruzi hypothetical protein, conserved 0.0414 0.432 1
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0048 0.0401 0.1645
Brugia malayi nuclear receptor NHR-67 0.0027 0.018 0.026
Loa Loa (eye worm) beta-lactamase 0.0078 0.0727 0.0724
Loa Loa (eye worm) kap beta 3 protein 0.0017 0.0068 0.0065
Plasmodium vivax acetyl-CoA synthetase, putative 0.0021 0.0114 0.0458
Entamoeba histolytica acyl-CoA synthetase, putative 0.0072 0.0656 0.2187
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0011 0.0011 0.0008
Mycobacterium ulcerans aldehyde dehydrogenase 0.0119 0.1169 0.1968
Trichomonas vaginalis DNA polymerase eta, putative 0.0061 0.0547 0.0701
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0021 0.0114 0.0163
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0011 0.0011 0.001
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0022 0.0122 0.0175
Mycobacterium ulcerans beta-lactamase 0.0078 0.0727 0.1222
Loa Loa (eye worm) hypothetical protein 0.0058 0.0505 0.0503
Loa Loa (eye worm) hypothetical protein 0.0011 0.0011 0.0008
Trypanosoma brucei Inositol phosphosphingolipids phospholipase C 0.0011 0.0011 0.0018
Leishmania major DNA polymerase eta, putative 0.009 0.0855 0.1959
Loa Loa (eye worm) hypothetical protein 0.0058 0.0505 0.0503
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0138 0.1368 0.1368
Mycobacterium ulcerans aldehyde dehydrogenase 0.0119 0.1169 0.1968
Onchocerca volvulus 0.0021 0.0114 0.0143
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0138 0.1368 0.1368
Loa Loa (eye worm) histone methyltransferase 0.0012 0.0018 0.0015
Echinococcus granulosus expressed conserved protein 0.01 0.0962 0.0962
Echinococcus multilocularis protein patched 0.0046 0.0379 0.0379
Loa Loa (eye worm) hypothetical protein 0.0046 0.0379 0.0376
Trichomonas vaginalis penicillin-binding protein, putative 0.0078 0.0727 0.0933
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0153 0.0618
Giardia lamblia hypothetical protein 0.0011 0.0011 0.0026
Brugia malayi nuclear receptor NHR-88 0.0027 0.018 0.026
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0289 0.2987 1
Schistosoma mansoni terminal deoxycytidyl transferase 0.0061 0.0547 0.0547
Brugia malayi photoreceptor-specific nuclear receptor 0.0058 0.0505 0.0739
Echinococcus granulosus geminin 0.036 0.3743 0.3743
Toxoplasma gondii HEAT repeat-containing protein 0.0017 0.0068 0.0268
Plasmodium falciparum ferrodoxin reductase-like protein 0.0022 0.0122 0.0491
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0058 0.0505 0.0505
Echinococcus multilocularis synaptojanin 1 0.0011 0.0011 0.0011
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0058 0.0505 0.0503
Giardia lamblia Thioredoxin reductase 0.0022 0.0122 0.0399
Echinococcus granulosus GPCR family 2 0.0031 0.0222 0.0222
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0021 0.0114 0.0114
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0011 0.0011 0.0026
Trypanosoma cruzi inositol 5-phosphatase 1, putative 0.0011 0.0011 0.0018
Brugia malayi tailless protein 0.0027 0.018 0.026
Brugia malayi Nuclear hormone receptor E75 0.0027 0.018 0.026
Onchocerca volvulus 0.0021 0.0114 0.0143
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0058 0.0505 0.0505
Leishmania major trypanothione reductase 0.0237 0.2424 0.56
Schistosoma mansoni cpg binding protein 0.0028 0.019 0.019
Echinococcus granulosus GTP binding nuclear protein Ran 0.0041 0.033 0.033
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0022 0.0122 0.0122
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0022 0.0122 0.0153
Entamoeba histolytica HEAT repeat domain containing protein 0.0017 0.0068 0.0218
Schistosoma mansoni cpg binding protein 0.003 0.0207 0.0207
Brugia malayi hypothetical protein 0.003 0.0215 0.0311
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0022 0.0122 0.0201
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0011 0.0011 0.0032
Echinococcus multilocularis GPCR, family 2 0.0031 0.0222 0.0222
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0027 0.018 0.018
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0082 0.0767 0.177
Trichomonas vaginalis skeletal muscle/kidney enriched inositol 5-phosphatase, putative 0.0011 0.0011 0.001
Echinococcus granulosus phd:f box containing protein 0.0018 0.0083 0.0083
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0011 0.0011 0.0026
Loa Loa (eye worm) jmjC domain-containing protein 0.0018 0.0083 0.008
Onchocerca volvulus 0.0072 0.0656 0.0841
Leishmania major DNA damage repair protein, putative 0.0019 0.0093 0.019
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0031 0.0222 0.0222
Schistosoma mansoni hypothetical protein 0.0031 0.0222 0.0222
Trichomonas vaginalis D-aminoacylase, putative 0.0078 0.0727 0.0933
Loa Loa (eye worm) hypothetical protein 0.0058 0.0505 0.0503
Brugia malayi F/Y-rich N-terminus family protein 0.0012 0.0017 0.0021
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0093 0.0208
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0058 0.0505 0.0505
Leishmania major pantothenate kinase subunit, putative 0.0014 0.0042 0.0073
Schistosoma mansoni nuclear receptor 0.0027 0.018 0.018
Brugia malayi ImpB/MucB/SamB family protein 0.0061 0.0547 0.0799
Mycobacterium ulcerans NADPH dependent 2,4-dienoyl-CoA reductase FadH 0.0022 0.0122 0.0201
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0021 0.0114 0.0187
Onchocerca volvulus 0.0058 0.0505 0.0648
Treponema pallidum thioredoxin reductase (trxB) 0.0022 0.0122 0.0399
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0058 0.0505 0.0505
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0072 0.0657 0.0843
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0072 0.0656 0.1034
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.054 0.5672 0.8977
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0011 0.0011 0.0012
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0119 0.1169 0.1169
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0021 0.0114 0.0257
Echinococcus multilocularis citrate lyase subunit beta protein 0.0048 0.0399 0.0399
Brugia malayi AMP-binding enzyme family protein 0.0072 0.0656 0.0959
Entamoeba histolytica disulphide oxidoreductase, putative 0.0022 0.0122 0.0399
Brugia malayi AMP-binding enzyme family protein 0.0021 0.0114 0.0163
Trichomonas vaginalis ran, putative 0.0041 0.033 0.0422
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0053 0.0462 0.0715
Mycobacterium leprae Probable UDP-galactopyranose mutase Glf (UDP-galp mutase) (NAD+-flavin adenine dinucleotide-requiring enzyme) 0.0563 0.5926 0.9381
Mycobacterium ulcerans acyl-CoA synthetase 0.0072 0.0656 0.1102
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0289 0.2987 0.3847
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0012 0.0018 0.0018
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0107 0.1031 0.3446
Treponema pallidum hypothetical protein 0.0011 0.0011 0.0026
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0011 0.0011 0.0032
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0124 0.1212 0.121
Trypanosoma cruzi mitochondrial protein 99, putative 0.0011 0.0011 0.0018
Brugia malayi jmjC domain containing protein 0.0018 0.0083 0.0117
Onchocerca volvulus 0.0028 0.019 0.0241
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0022 0.0122 0.0399
Brugia malayi nuclear hormone receptor 0.0027 0.018 0.026
Brugia malayi jmjC domain containing protein 0.007 0.0633 0.0927
Trypanosoma brucei DNA polymerase kappa, putative 0.0061 0.0547 0.1259
Loa Loa (eye worm) hypothetical protein 0.0058 0.0505 0.0503
Trypanosoma brucei DNA polymerase kappa, putative 0.0061 0.0547 0.1259
Loa Loa (eye worm) hypothetical protein 0.0078 0.0727 0.0724
Trypanosoma cruzi mitochondrial protein 99, putative 0.0011 0.0011 0.0018
Entamoeba histolytica hypothetical protein 0.0072 0.0657 0.2191
Brugia malayi ecdysteroid receptor 0.0058 0.0505 0.0739
Trypanosoma cruzi DNA polymerase eta, putative 0.0048 0.0401 0.0923
Loa Loa (eye worm) hypothetical protein 0.02 0.2027 0.2025
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0153 0.0346
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0944 1 1
Loa Loa (eye worm) hypothetical protein 0.0058 0.0505 0.0503
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0289 0.2987 0.3847
Trichomonas vaginalis glutamate synthase, putative 0.0022 0.0122 0.0153
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0021 0.0114 0.0187
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0011 0.0011 0.0032
Trypanosoma brucei hypothetical protein, conserved 0.0019 0.0093 0.0208
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0022 0.0122 0.0258
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0011 0.0011 0.0018
Mycobacterium ulcerans hypothetical protein 0.0022 0.0122 0.0201
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0011 0.0011 0.0018
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0058 0.0505 0.0739
Trypanosoma cruzi hypothetical protein, conserved 0.0022 0.0122 0.0276
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0031 0.0222 0.0222
Entamoeba histolytica hypothetical protein 0.007 0.0637 0.2126
Brugia malayi steroid hormone receptor 0.0058 0.0505 0.0739
Mycobacterium tuberculosis Probable esterase LipL 0.0078 0.0727 0.1135
Mycobacterium tuberculosis UDP-galactopyranose mutase Glf (UDP-GALP mutase) (NAD+-flavin adenine dinucleotide-requiring enzyme) 0.0563 0.5926 0.938
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0058 0.0505 0.0505
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0082 0.0767 0.3157
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0078 0.0727 0.0727
Trypanosoma brucei inositol-1,4,5-trisphosphate (IP3) 5-phosphatase, putative 0.0011 0.0011 0.0018
Brugia malayi RNA, U transporter 1 0.0251 0.2582 0.3792
Trichomonas vaginalis type II inositol 5-phosphatase, putative 0.0011 0.0011 0.001
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0021 0.0114 0.0163
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0089 0.0843 0.0843
Brugia malayi AMP-binding enzyme family protein 0.0072 0.0656 0.0959
Echinococcus multilocularis deoxyribonuclease 1 2 0.0011 0.0011 0.0011
Brugia malayi ImpB/MucB/SamB family protein 0.009 0.0855 0.1252
Schistosoma mansoni hypothetical protein 0.0031 0.0222 0.0222
Echinococcus multilocularis dna polymerase kappa 0.0061 0.0547 0.0547
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0053 0.0462 0.0774
Treponema pallidum fructose-bisphosphate aldolase 0.0289 0.2987 1
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0011 0.0011 0.0018
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0058 0.0505 0.0505
Plasmodium vivax acyl-CoA synthetase, putative 0.0053 0.0462 0.1895
Mycobacterium ulcerans NADH dehydrogenase Ndh1 0.0022 0.0122 0.0201
Brugia malayi jmjC domain containing protein 0.0018 0.0083 0.0117
Mycobacterium leprae Probable NADPH:adrenodoxin oxidoreductase FprA (NADPH-FERREDOXIN REDUCTASE) 0.0022 0.0122 0.0188
Echinococcus granulosus neutral sphingomyelinase 0.0011 0.0011 0.0011
Entamoeba histolytica acyl-CoA synthetase, putative 0.0072 0.0656 0.2187
Trichomonas vaginalis sphingomyelinase C 2 precursor, putative 0.0011 0.0011 0.001
Mycobacterium ulcerans acyl-CoA synthetase 0.0072 0.0656 0.1102
Schistosoma mansoni cript-related 0.0011 0.0011 0.0011
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0011 0.0011 0.0032
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0022 0.0122 0.1556
Onchocerca volvulus Protein ultraspiracle homolog 0.0058 0.0505 0.0648
Plasmodium vivax thioredoxin reductase, putative 0.0237 0.2424 1
Loa Loa (eye worm) programmed cell death 8 0.0022 0.0122 0.0119
Trichomonas vaginalis penicillin-binding protein, putative 0.0078 0.0727 0.0933
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0056 0.0493 0.0491
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0019 0.0093 0.0371
Plasmodium vivax DNA repair protein REV1, putative 0.0019 0.0093 0.0371
Brugia malayi nuclear hormone receptor family member odr-7 0.0027 0.018 0.026
Echinococcus multilocularis dna polymerase eta 0.009 0.0855 0.0855
Echinococcus multilocularis Niemann Pick C1 protein 0.0152 0.1521 0.1521
Echinococcus granulosus lysine specific demethylase 6a 0.0018 0.0083 0.0083
Echinococcus granulosus glutamate synthase 0.0022 0.0122 0.0122
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0011 0.0011 0.0012
Mycobacterium tuberculosis Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0022 0.0122 0.0176
Trypanosoma brucei importin beta-1 subunit, putative 0.0088 0.0836 0.1929
Leishmania major acetyl-CoA synthetase, putative 0.0021 0.0114 0.0239
Schistosoma mansoni hypothetical protein 0.0044 0.0361 0.0361
Mycobacterium tuberculosis Probable lipase LipE 0.0078 0.0727 0.1135
Brugia malayi AMP-binding enzyme family protein 0.0021 0.0114 0.0163
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0021 0.0114 0.0176
Leishmania major hypothetical protein, conserved 0.0414 0.432 1
Echinococcus multilocularis nibrin 0.0011 0.0003 0.0003
Trypanosoma brucei DNA damage repair protein, putative 0.0019 0.0093 0.0208
Onchocerca volvulus 0.0078 0.0727 0.0933
Leishmania major 4-coumarate:coa ligase-like protein 0.0072 0.0656 0.1496
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0022 0.0122 0.0175
Loa Loa (eye worm) hypothetical protein 0.0027 0.018 0.0177
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0056 0.0493 0.1644
Echinococcus multilocularis inositol polyphosphate 5 phosphatase OCRL 1 0.0011 0.0011 0.0011
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0093 0.0886 0.0886
Loa Loa (eye worm) CCR4-NOT transcription complex subunit 6 family protein 0.0012 0.0013 0.001
Plasmodium falciparum JmjC domain-containing protein, putative 0.0018 0.0083 0.033
Trypanosoma cruzi trypanothione reductase, putative 0.0237 0.2424 0.5608
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0053 0.0462 0.6002
Echinococcus granulosus inositol polyphosphate 5 phosphatase OCRL 1 0.0011 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0027 0.018 0.0177
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.054 0.5672 0.8977
Echinococcus granulosus nibrin 0.0011 0.0003 0.0003
Mycobacterium ulcerans NADH dehydrogenase 0.0022 0.0122 0.0201
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0078 0.0727 0.1135
Giardia lamblia Inositol 5-phosphatase 4 0.0011 0.0011 0.0026
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0018 0.0083 0.033
Loa Loa (eye worm) hypothetical protein 0.0027 0.018 0.0177
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0018 0.0083 0.0185
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0093 0.0886 0.0886
Mycobacterium leprae Probable lipase LipE 0.0078 0.0727 0.1146
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0052 0.0448 0.0655
Echinococcus granulosus Nuclear hormone receptor HR96 0.0027 0.018 0.018
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0082 0.0767 0.12
Schistosoma mansoni aldehyde dehydrogenase 0.0119 0.1169 0.1169
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0011 0.0011 0.0018
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0027 0.018 0.018
Echinococcus multilocularis phd:f box containing protein 0.0018 0.0083 0.0083
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0041 0.033 0.0327
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0058 0.0505 0.0505
Trypanosoma brucei unspecified product 0.0061 0.0547 0.1259
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0022 0.0122 0.0491
Trypanosoma brucei DNA polymerase kappa, putative 0.0061 0.0547 0.1259
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0072 0.0656 0.1102
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0082 0.0767 1
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0022 0.0122 0.0153
Echinococcus multilocularis importin subunit beta 1 0.0088 0.0836 0.0836
Schistosoma mansoni cpg binding protein 0.003 0.0207 0.0207
Schistosoma mansoni hypothetical protein 0.0067 0.061 0.061
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0022 0.0122 0.0153
Onchocerca volvulus 0.0027 0.018 0.0228
Echinococcus multilocularis traf and tnf receptor associated protein 0.0011 0.0011 0.0011
Brugia malayi AMP-binding enzyme family protein 0.0021 0.0114 0.0163
Mycobacterium ulcerans acetyl-CoA synthetase 0.0021 0.0114 0.0187
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0289 0.2987 0.3847
Mycobacterium ulcerans DNA polymerase IV 0.0061 0.0547 0.0918
Onchocerca volvulus Bile acid receptor homolog 0.0058 0.0505 0.0648
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0093 0.0886 0.0886
Trypanosoma cruzi DNA polymerase kappa, putative 0.0061 0.0547 0.1259
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.06 0.6317 1
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0022 0.0122 0.0491
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0027 0.018 0.026
Schistosoma mansoni DNA polymerase IV / kappa 0.0019 0.0093 0.0093
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0056 0.0493 0.1136
Brugia malayi nuclear receptor NHR-88 0.0058 0.0505 0.0739
Loa Loa (eye worm) hypothetical protein 0.003 0.0215 0.0212
Loa Loa (eye worm) hypothetical protein 0.0018 0.0083 0.008
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0041 0.033 0.0758
Toxoplasma gondii exonuclease III APE 0.0056 0.0493 0.2026
Plasmodium vivax hypothetical protein, conserved 0.0011 0.0011 0.0032
Schistosoma mansoni disulfide oxidoreductase 0.0022 0.0122 0.0122
Echinococcus multilocularis beta LACTamase domain containing family member 0.0078 0.0727 0.0727
Schistosoma mansoni steroid hormone receptor ad4bp 0.0058 0.0505 0.0505
Schistosoma mansoni transcription factor LCR-F1 0.007 0.0637 0.0637
Loa Loa (eye worm) steroid hormone receptor 0.0058 0.0505 0.0503
Loa Loa (eye worm) hypothetical protein 0.0027 0.018 0.0177
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0021 0.0114 0.0163
Onchocerca volvulus 0.0011 0.0011 0.001
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0011 0.0011 0.0018
Brugia malayi nuclear receptor RXR 0.0027 0.018 0.026
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0022 0.0122 0.0153
Loa Loa (eye worm) hypothetical protein 0.0011 0.0011 0.0008
Wolbachia endosymbiont of Brugia malayi NADPH-dependent glutamate synthase beta chain 0.0022 0.0122 0.1556
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0021 0.0114 0.0163
Trypanosoma brucei importin beta-1 subunit, putative 0.0088 0.0836 0.1929
Trichomonas vaginalis importin beta-1, putative 0.0072 0.0657 0.0843
Loa Loa (eye worm) hypothetical protein 0.0053 0.0462 0.0459
Plasmodium falciparum transportin 0.0017 0.0068 0.0268
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0058 0.0505 0.0505
Mycobacterium ulcerans NADH dehydrogenase Ndh 0.0022 0.0122 0.0201
Echinococcus multilocularis glutamate synthase 0.0022 0.0122 0.0122
Trypanosoma brucei DNA polymerase kappa, putative 0.0061 0.0547 0.1259
Schistosoma mansoni thyroid hormone receptor 0.0058 0.0505 0.0505
Schistosoma mansoni retinoic acid receptor RXR 0.0058 0.0505 0.0505
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0022 0.0122 0.0122
Chlamydia trachomatis thioredoxin reductase 0.0022 0.0122 0.1556
Trypanosoma brucei DNA damage repair protein, putative 0.0019 0.0093 0.0208
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0058 0.0505 0.0505
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0021 0.0114 0.0163
Echinococcus granulosus tar DNA binding protein 0.0124 0.1212 0.1212
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0022 0.0122 0.0276
Loa Loa (eye worm) hypothetical protein 0.0056 0.0489 0.0486
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0011 0.0011 0.001
Echinococcus multilocularis transportin 1 0.0017 0.0068 0.0068
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0022 0.0122 0.0399
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0056 0.0493 0.0765
Trichomonas vaginalis apoptosis inducing factor, putative 0.0022 0.0122 0.0153
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0061 0.0547 0.0849
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0058 0.0505 0.0739
Trypanosoma brucei RNA editing exonuclease 2 0.0011 0.0011 0.0018
Echinococcus multilocularis expressed conserved protein 0.01 0.0962 0.0962
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprB 0.0022 0.0122 0.0201
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0021 0.0114 0.0458
Schistosoma mansoni sulfide quinone reductase 0.0022 0.0122 0.0122
Schistosoma mansoni phosphatidylserine receptor 0.0018 0.0083 0.0083
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0082 0.0767 0.129
Brugia malayi RNA binding protein 0.0124 0.1212 0.1778
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0012 0.0018 0.0018
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0022 0.0122 0.0122
Schistosoma mansoni carbon catabolite repressor protein 0.0011 0.0011 0.0011
Schistosoma mansoni hypothetical protein 0.04 0.4174 0.4174
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.002 0.01 0.01
Onchocerca volvulus 0.0021 0.0114 0.0143
Toxoplasma gondii NADPH-glutathione reductase 0.0082 0.0767 0.3157
Loa Loa (eye worm) hypothetical protein 0.0027 0.018 0.0177
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.007 0.0637 0.0637
Plasmodium falciparum importin beta, putative 0.0088 0.0836 0.344
Brugia malayi Nuclear hormone receptor-like 1 0.003 0.0215 0.0311
Trichomonas vaginalis ap endonuclease, putative 0.0056 0.0493 0.0632
Trypanosoma brucei inositol/phosphatidylinositol phosphatase, putative 0.0011 0.0011 0.0018
Brugia malayi hypothetical protein 0.0027 0.018 0.026
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0114 0.0187
Brugia malayi hypothetical protein 0.0085 0.0802 0.1175
Schistosoma mansoni eyes absent homolog 0.0085 0.0802 0.0802
Mycobacterium leprae Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0022 0.0122 0.0188
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0048 0.0399 0.0669
Schistosoma mansoni sulfide quinone reductase 0.0022 0.0122 0.0122
Toxoplasma gondii histone lysine methyltransferase SET1 0.0057 0.0495 0.2034
Schistosoma mansoni hypothetical protein 0.036 0.3743 0.3743
Schistosoma mansoni ocrl type II inositol 5-phosphatase 0.0011 0.0011 0.0011
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0082 0.0767 0.3157
Loa Loa (eye worm) nuclear hormone receptor 0.0027 0.018 0.0177
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0061 0.0547 0.0544
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0072 0.0656 0.1034
Brugia malayi MH2 domain containing protein 0.0115 0.1125 0.1649
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0058 0.0505 0.0739
Loa Loa (eye worm) nuclear receptor NHR-67 0.0027 0.018 0.0177
Schistosoma mansoni synaptojanin 0.0011 0.0011 0.0011
Schistosoma mansoni nuclear receptor 0.0027 0.018 0.018
Trypanosoma cruzi DNA polymerase kappa, putative 0.0061 0.0547 0.1259
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0082 0.0767 0.129
Mycobacterium tuberculosis Conserved protein 0.0078 0.0727 0.1135
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0011 0.0003 0.00000041586
Mycobacterium leprae conserved hypothetical protein 0.0078 0.0727 0.1146
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0058 0.0505 0.0739
Trichomonas vaginalis ocrl type II inositol 5-phosphatase, putative 0.0011 0.0011 0.001
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0061 0.0547 0.1243
Schistosoma mansoni hypothetical protein 0.0011 0.0011 0.0011
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0022 0.0122 0.1556
Loa Loa (eye worm) hypothetical protein 0.0027 0.018 0.0177
Schistosoma mansoni jumonji domain containing protein 0.0068 0.0616 0.0616
Giardia lamblia DNA damage repair protein 0.0019 0.0093 0.0301
Schistosoma mansoni jumonji domain containing protein 0.0018 0.0083 0.0083
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0041 0.033 0.0758
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0021 0.0114 0.0187
Entamoeba histolytica hypothetical protein 0.007 0.0637 0.2126
Trypanosoma cruzi NADH dehydrogenase, putative 0.0022 0.0122 0.0276
Echinococcus multilocularis lysine specific demethylase 6a 0.0018 0.0083 0.0083
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0011 0.0011 0.0012
Loa Loa (eye worm) hypothetical protein 0.0027 0.018 0.0177
Plasmodium falciparum endonuclease/exonuclease/phosphatase family protein, putative 0.0011 0.0011 0.0032
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0011 0.0011 0.0012
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0058 0.0505 0.0505
Brugia malayi nuclear hormone receptor 0.0058 0.0505 0.0739
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0011 0.0011 0.0011
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0072 0.0656 0.1022
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0048 0.0403 0.0926
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0058 0.0505 0.0505
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0056 0.0493 0.1136
Schistosoma mansoni nuclear hormone receptor 0.0027 0.018 0.018
Loa Loa (eye worm) hypothetical protein 0.0078 0.0727 0.0724
Trichomonas vaginalis ap endonuclease, putative 0.0056 0.0493 0.0632
Mycobacterium ulcerans DNA polymerase IV 0.0061 0.0547 0.0918
Onchocerca volvulus 0.0052 0.0448 0.0574
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0011 0.0011 0.0012
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0082 0.0767 0.0767
Brugia malayi exodeoxyribonuclease III family protein 0.0056 0.0493 0.0721
Trypanosoma brucei hypothetical protein, conserved 0.0078 0.0727 0.1676
Trypanosoma cruzi DNA polymerase kappa, putative 0.0061 0.0547 0.1259
Giardia lamblia NADH oxidase lateral transfer candidate 0.0082 0.0767 0.2562
Schistosoma mansoni importin beta-1 0.0088 0.0836 0.0836
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0021 0.0114 0.0458
Echinococcus granulosus Niemann Pick C1 protein 0.0107 0.1031 0.1031
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0058 0.0505 0.0505
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0341 0.3544 0.8204
Echinococcus multilocularis survival motor neuron protein 1 0.0256 0.2633 0.2633
Mycobacterium ulcerans acyl-CoA synthetase 0.0072 0.0656 0.1102
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0048 0.0403 0.0926
Entamoeba histolytica endonuclease/exonuclease/phosphatase domain containing protein 0.0011 0.0011 0.0026
Trichomonas vaginalis antibiotic synthetase, putative 0.0021 0.0114 0.0143
Brugia malayi glutamate synthase 0.0022 0.0122 0.0175
Trypanosoma brucei hypothetical protein, conserved 0.0022 0.0122 0.0276
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0022 0.0122 0.0122
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0161 0.1619 0.3743
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0011 0.0011 0.0008
Loa Loa (eye worm) transcription factor SMAD2 0.0115 0.1125 0.1122
Leishmania major hypothetical protein, conserved 0.0078 0.0727 0.1661
Schistosoma mansoni tar DNA-binding protein 0.0124 0.1212 0.1212
Loa Loa (eye worm) hypothetical protein 0.0027 0.018 0.0177
Leishmania major mitochondrial DNA polymerase beta 0.0341 0.3544 0.82
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0098 0.0943 0.094
Toxoplasma gondii propionate-CoA ligase 0.0021 0.0114 0.0458
Entamoeba histolytica hypothetical protein 0.007 0.0637 0.2126
Brugia malayi hypothetical protein 0.007 0.0637 0.0932
Mycobacterium ulcerans lipase LipD 0.0078 0.0727 0.1222
Trypanosoma cruzi DNA damage repair protein, putative 0.0019 0.0093 0.0208
Loa Loa (eye worm) hypothetical protein 0.0011 0.0011 0.0008
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0068 0.0616 0.0616
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0138 0.1368 0.2006
Mycobacterium tuberculosis Probable citrate (pro-3S)-lyase (beta subunit) CitE (citrase) (citratase) (citritase) (citridesmolase) (citrase aldolase) 0.0048 0.0399 0.0616
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0058 0.0505 0.0505
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0058 0.0505 0.0503
Schistosoma mansoni glutamate synthase 0.0022 0.0122 0.0122
Brugia malayi hypothetical protein 0.0256 0.2633 0.3866
Trypanosoma brucei DNA polymerase IV, putative 0.0061 0.0547 0.1259
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0051 0.043 0.0665
Loa Loa (eye worm) hypothetical protein 0.0027 0.018 0.0177
Trypanosoma brucei ULK family serine/threonine-protein kinase, putative 0.0017 0.0068 0.015
Onchocerca volvulus 0.0078 0.0727 0.0933
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0021 0.0114 0.0163
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0021 0.0114 0.0176
Mycobacterium ulcerans thioredoxin reductase TrxB2 0.0022 0.0122 0.0201
Brugia malayi hypothetical protein 0.003 0.0215 0.0311
Brugia malayi RNA recognition motif domain containing protein 0.0124 0.1212 0.1778
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0082 0.0767 0.1755
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0056 0.0493 0.1136
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0342 0.0786
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0082 0.0767 0.1124
Trypanosoma cruzi NADH dehydrogenase, putative 0.0022 0.0122 0.0276
Schistosoma mansoni coup transcription factor 0.0058 0.0505 0.0505
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0011 0.0011 0.0018
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0022 0.0122 0.0122
Echinococcus multilocularis ecdysone induced protein 78C 0.0058 0.0505 0.0505
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0061 0.0547 0.0701
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0022 0.0122 0.0201
Loa Loa (eye worm) hypothetical protein 0.0018 0.0083 0.008
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0011 0.0011 0.0018
Brugia malayi orphan nuclear receptor NR2E1 0.0027 0.018 0.026
Echinococcus granulosus replication factor c subunit 1 0.0011 0.0003 0.0003
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0082 0.0767 0.177
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0082 0.0767 0.177
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0058 0.0505 0.0739
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0058 0.0505 0.0503
Loa Loa (eye worm) hypothetical protein 0.0058 0.0505 0.0503
Schistosoma mansoni hypothetical protein 0.0052 0.0448 0.0448
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0019 0.0093 0.0371
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.054 0.5672 0.8978
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0041 0.033 0.1097
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0082 0.0767 0.1755
Echinococcus multilocularis translational activator gcn1 0.0017 0.0068 0.0068
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.002 0.01 0.01
Loa Loa (eye worm) hypothetical protein 0.003 0.0215 0.0212
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0041 0.033 0.0758
Echinococcus granulosus citrate lyase subunit beta protein 0.0048 0.0399 0.0399
Plasmodium vivax endonuclease/exonuclease/phosphatase domain containing protein 0.0011 0.0011 0.0032
Brugia malayi hypothetical protein 0.0016 0.0059 0.0082
Loa Loa (eye worm) importin-beta domain-containing protein 0.0017 0.0068 0.0065
Trypanosoma cruzi hypothetical protein, conserved 0.0078 0.0727 0.1676
Trichomonas vaginalis Citrate lyase beta chain, putative 0.0048 0.0399 0.0511
Leishmania major 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0048 0.0399 0.0901
Brugia malayi hypothetical protein 0.0027 0.018 0.026
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0058 0.0515 0.1187
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0021 0.0114 0.0187
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0021 0.0114 0.0239
Plasmodium vivax ferrodoxin reductase, putative 0.0022 0.0122 0.0491
Schistosoma mansoni hypothetical protein 0.0011 0.0007 0.0007
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0078 0.0727 0.1135
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0048 0.0399 0.0669
Loa Loa (eye worm) thioredoxin reductase 0.0237 0.2424 0.2422
Brugia malayi Pre-SET motif family protein 0.0093 0.0886 0.1299
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0056 0.0493 0.0828
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0082 0.0767 0.177
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0082 0.0767 0.177
Mycobacterium ulcerans hypothetical protein 0.0019 0.0093 0.0152
Mycobacterium ulcerans hypothetical protein 0.0048 0.0399 0.0669
Schistosoma mansoni nuclear hormone receptor 0.0058 0.0505 0.0505
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.054 0.5672 0.8977
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0022 0.0122 0.0122
Loa Loa (eye worm) RNA binding protein 0.0124 0.1212 0.121
Brugia malayi beta-lactamase family protein 0.0078 0.0727 0.1064
Leishmania major DNA polymerase kappa, putative 0.0061 0.0547 0.1243
Loa Loa (eye worm) hypothetical protein 0.0078 0.0727 0.0724
Schistosoma mansoni nuclear hormone receptor 0.0027 0.018 0.018
Mycobacterium tuberculosis Conserved protein 0.0078 0.0727 0.1135
Mycobacterium tuberculosis Probable thioredoxin reductase TrxB2 (TRXR) (TR) 0.0022 0.0122 0.0176
Leishmania major DNA polymerase eta, putative 0.0048 0.0401 0.0906
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.006 0.0534 0.0781
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0041 0.033 0.1352
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0027 0.018 0.0228
Trypanosoma cruzi importin beta-1 subunit, putative 0.0072 0.0657 0.1514
Trypanosoma brucei Importin-beta N-terminal domain/HEAT-like repeat, putative 0.0017 0.0068 0.015
Echinococcus granulosus transportin 1 0.0017 0.0068 0.0068
Mycobacterium ulcerans aldehyde dehydrogenase 0.0119 0.1169 0.1968
Echinococcus multilocularis jumonji domain containing 1A 0.0018 0.0083 0.0083
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0021 0.0114 0.0163
Mycobacterium tuberculosis NADPH:adrenodoxin oxidoreductase FprA (NADPH-ferredoxin reductase) 0.0022 0.0122 0.0176
Trypanosoma brucei DNA polymerase kappa, putative 0.0061 0.0547 0.1259
Plasmodium falciparum glutathione reductase 0.0082 0.0767 0.3157
Mycobacterium tuberculosis Probable NADPH dependent 2,4-dienoyl-CoA reductase FadH (2,4-dienoyl coenzyme A reductase) (4-enoyl-CoA reductase) 0.0022 0.0122 0.0176
Leishmania major 4-coumarate:coa ligase-like protein 0.0072 0.0656 0.1496
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0018 0.0083 0.0185
Trypanosoma cruzi hypothetical protein, conserved 0.0022 0.0122 0.0276
Toxoplasma gondii hypothetical protein 0.0055 0.0478 0.1964
Loa Loa (eye worm) hypothetical protein 0.003 0.0215 0.0212
Loa Loa (eye worm) hypothetical protein 0.0022 0.0122 0.0119
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0138 0.1368 0.1368
Entamoeba histolytica deoxycytidyl transferase, putative 0.0061 0.0547 0.1822
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0022 0.0122 0.0153
Brugia malayi polk-prov protein 0.0019 0.0093 0.0132
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0289 0.2987 0.3847
Trypanosoma brucei unspecified product 0.0042 0.0342 0.0786
Onchocerca volvulus 0.0011 0.0011 0.001
Plasmodium falciparum exodeoxyribonuclease III, putative 0.0011 0.0011 0.0032
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.0011 0.0003 0.0000010811
Schistosoma mansoni jumonji/arid domain-containing protein 0.007 0.0633 0.0633
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0093 0.0886 0.0886
Plasmodium vivax SET domain protein, putative 0.0093 0.0886 0.3649
Echinococcus granulosus cpg binding protein 0.003 0.0207 0.0207
Echinococcus multilocularis Niemann Pick C1 protein 0.0107 0.1031 0.1031
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0082 0.0767 0.177
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0058 0.0505 0.0505
Toxoplasma gondii HEAT repeat-containing protein 0.0017 0.0068 0.0268
Plasmodium falciparum carbon catabolite repressor protein 4, putative 0.0011 0.0011 0.0032
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0027 0.018 0.018
Trichomonas vaginalis D-aminoacylase, putative 0.0078 0.0727 0.0933
Plasmodium vivax importin-beta 2, putative 0.0088 0.0836 0.344
Giardia lamblia Fructose-bisphosphate aldolase 0.0289 0.2987 1
Loa Loa (eye worm) hypothetical protein 0.0011 0.0011 0.0008
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0027 0.018 0.018
Brugia malayi CXXC zinc finger family protein 0.0028 0.019 0.0274
Brugia malayi beta-lactamase 0.0078 0.0727 0.1064
Brugia malayi Nuclear hormone receptor-like 1 0.0058 0.0505 0.0739
Plasmodium vivax transportin, putative 0.0017 0.0068 0.0268
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0153 0.0618
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0022 0.0122 0.0175
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0072 0.0656 0.1102
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0093 0.0886 0.3649
Schistosoma mansoni ran 0.0041 0.033 0.033
Schistosoma mansoni tar DNA-binding protein 0.0124 0.1212 0.1212
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0021 0.0114 0.0114
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0082 0.0767 0.177
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0027 0.018 0.018
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0078 0.0727 0.0724
Leishmania major hypothetical protein, conserved 0.0022 0.0122 0.0258
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0022 0.0122 0.0491
Loa Loa (eye worm) hypothetical protein 0.0093 0.0886 0.0884
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0046 0.0379 0.0376
Trypanosoma cruzi hypothetical protein, conserved 0.0078 0.0727 0.1676
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0022 0.0122 0.0491
Brugia malayi CHE-14 protein 0.0046 0.0379 0.0553
Trypanosoma brucei DNA polymerase eta, putative 0.009 0.0855 0.1973
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0021 0.0114 0.0111
Echinococcus granulosus Nuclear hormone receptor HR96 0.0027 0.018 0.018
Schistosoma mansoni ran 0.0041 0.033 0.033
Plasmodium vivax glutathione reductase, putative 0.0237 0.2424 1
Trypanosoma cruzi DNA polymerase kappa, putative 0.0061 0.0547 0.1259
Treponema pallidum exodeoxyribonuclease (exoA) 0.0056 0.0493 0.1644
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.06 0.6317 1
Loa Loa (eye worm) hypothetical protein 0.0021 0.0114 0.0111
Echinococcus granulosus importin 5 0.0017 0.0068 0.0068
Echinococcus granulosus ecdysone induced protein 78C 0.0058 0.0505 0.0505
Mycobacterium ulcerans hypothetical protein 0.0048 0.0399 0.0669
Mycobacterium leprae THIOREDOXIN TRXC (TRX) (MPT46) 0.0022 0.0122 0.0188
Schistosoma mansoni tar DNA-binding protein 0.0124 0.1212 0.1212
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0082 0.0767 0.1755
Trypanosoma brucei DNA-(apurinic or apyrimidinic site) lyase, putative 0.0011 0.0011 0.0018
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0051 0.043 0.0665
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0058 0.0505 0.0739
Schistosoma mansoni survival motor neuron protein 0.0052 0.0448 0.0448
Trypanosoma brucei DNA polymerase IV, putative 0.0061 0.0547 0.1259
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0051 0.043 0.0665
Loa Loa (eye worm) oxidoreductase 0.0021 0.0114 0.0111
Loa Loa (eye worm) hypothetical protein 0.003 0.0215 0.0212
Trypanosoma cruzi endonuclease/exonuclease/phosphatase, putative 0.0011 0.0011 0.0018
Schistosoma mansoni ap endonuclease 0.0056 0.0493 0.0493
Loa Loa (eye worm) TAR-binding protein 0.0124 0.1212 0.121
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0011 0.0011 0.0032
Echinococcus multilocularis nuclear receptor nhr 48 0.0027 0.018 0.018
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0048 0.0399 0.0917
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0021 0.0114 0.0257
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0048 0.0403 0.0926
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0342 0.0786
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.003 0.0215 0.0215
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0114 0.0187
Trypanosoma brucei DNA polymerase kappa, putative 0.0061 0.0547 0.1259
Toxoplasma gondii ABC1 family protein 0.0078 0.0727 0.2989
Echinococcus multilocularis thyroid hormone receptor alpha 0.0058 0.0505 0.0505
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0138 0.1368 0.1368
Loa Loa (eye worm) DR-78 0.0027 0.018 0.0177
Schistosoma mansoni importin-beta 2 0.0017 0.0068 0.0068
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0058 0.0505 0.0739
Loa Loa (eye worm) hypothetical protein 0.0072 0.0656 0.0653
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0341 0.3544 0.8204
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0289 0.2987 0.3847
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0011 0.0011 0.0008
Mycobacterium ulcerans hypothetical protein 0.0072 0.0656 0.1102
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0068 0.0616 0.0616
Loa Loa (eye worm) hypothetical protein 0.0078 0.0727 0.0724
Echinococcus multilocularis snurportin 1 0.0944 1 1
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0082 0.0767 0.0767
Echinococcus multilocularis geminin 0.036 0.3743 0.3743
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0153 0.0346
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0021 0.0114 0.0187
Loa Loa (eye worm) hypothetical protein 0.0072 0.0656 0.0653
Trypanosoma cruzi hypothetical protein, conserved 0.0019 0.0093 0.0208
Echinococcus multilocularis thioredoxin glutathione reductase 0.0237 0.2424 0.2424
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0011 0.0011 0.0026
Trichomonas vaginalis glutamate synthase, putative 0.0022 0.0122 0.0153
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0027 0.018 0.0228
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0011 0.0011 0.0018
Schistosoma mansoni aldehyde dehydrogenase 0.0119 0.1169 0.1169
Loa Loa (eye worm) hypothetical protein 0.0256 0.2633 0.263
Toxoplasma gondii thioredoxin reductase 0.0237 0.2424 1
Trypanosoma brucei NADH dehydrogenase 0.0022 0.0122 0.0276
Plasmodium falciparum thioredoxin reductase 0.0082 0.0767 0.3157
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0058 0.0505 0.0503
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0021 0.0114 0.0257
Onchocerca volvulus 0.0093 0.0886 0.1139
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0153 0.0618
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0063 0.0564 0.0564
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0021 0.0114 0.0372
Echinococcus multilocularis importin 5 0.0017 0.0068 0.0068
Echinococcus granulosus Protein patched homolog 1 0.0046 0.0379 0.0379
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0022 0.0122 0.0491
Echinococcus multilocularis tar DNA binding protein 0.0124 0.1212 0.1212
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0022 0.0122 0.0491
Schistosoma mansoni topbp1 0.0011 0.0003 0.0003
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0093 0.0886 0.0886
Brugia malayi Latrophilin receptor protein 2 0.0031 0.0222 0.0323
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0056 0.0493 0.0493
Trypanosoma cruzi hypothetical protein, conserved 0.0019 0.0093 0.0208
Brugia malayi Thioredoxin reductase 0.0237 0.2424 0.3559
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0022 0.0122 0.0153
Loa Loa (eye worm) hypothetical protein 0.0085 0.0802 0.0799
Echinococcus multilocularis CCR4 NOT transcription complex subunit 6 0.0011 0.0011 0.0011
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0379 0.0485
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0022 0.0122 0.0276
Loa Loa (eye worm) hypothetical protein 0.0027 0.018 0.0177
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0022 0.0122 0.0276
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0342 0.0786
Loa Loa (eye worm) jmjC domain-containing protein 0.007 0.0633 0.0631
Trypanosoma brucei hypothetical protein, conserved 0.0019 0.0093 0.0208
Trypanosoma brucei trypanothione reductase 0.0237 0.2424 0.5608
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0082 0.0767 0.177
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0082 0.0767 0.177
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0011 0.0011 0.0012
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0022 0.0122 0.0122
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0022 0.0122 0.0122
Brugia malayi jmjC domain containing protein 0.0018 0.0083 0.0117
Echinococcus granulosus traf and tnf receptor associated protein 0.0011 0.0011 0.0011
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0153 0.0618
Echinococcus granulosus dna polymerase kappa 0.0061 0.0547 0.0547
Schistosoma mansoni chromosome transmission fidelity factor 0.0011 0.0003 0.0003
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.003 0.0215 0.0215
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.006 0.0534 0.0781
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0645 0.6805 0.6804
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0011 0.0007 0.0007
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0022 0.0122 0.0276
Brugia malayi Steroid receptor seven-up type 2 0.0058 0.0505 0.0739
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0021 0.0114 0.0187
Echinococcus multilocularis cpg binding protein 0.003 0.0207 0.0207
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0138 0.1368 0.1368
Loa Loa (eye worm) hypothetical protein 0.0078 0.0727 0.0724
Brugia malayi nuclear receptor RXR 0.003 0.0215 0.0311
Loa Loa (eye worm) hypothetical protein 0.0018 0.0083 0.008
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0031 0.0222 0.0323
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0011 0.0007 0.0007
Brugia malayi nuclear hormone receptor family member nhr-6 0.0027 0.018 0.026
Loa Loa (eye worm) hypothetical protein 0.0027 0.018 0.0177
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0022 0.0122 0.0153
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0082 0.0767 0.1755
Schistosoma mansoni jumonji/arid domain-containing protein 0.007 0.0633 0.0633

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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