Detailed information for compound 801621

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 472.94 | Formula: C24H26ClFN4O3
  • H donors: 2 H acceptors: 2 LogP: 3.17 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCOC(=O)C1=C(CN2CCN(CC2)c2ccc(cc2)F)NC(=O)NC1c1ccc(cc1)Cl
  • InChi: 1S/C24H26ClFN4O3/c1-2-33-23(31)21-20(27-24(32)28-22(21)16-3-5-17(25)6-4-16)15-29-11-13-30(14-12-29)19-9-7-18(26)8-10-19/h3-10,22H,2,11-15H2,1H3,(H2,27,28,32)
  • InChiKey: GQKKAQHBGSDVTI-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0189 0.0129 0.0129
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0167 0.0114 0.0316
Loa Loa (eye worm) intermediate filament protein 0.0025 0.001 0.001
Echinococcus multilocularis carboxylesterase 5A 0.0063 0.0038 0.0106
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0029 0.0013 0.0033
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0058 0.0034 0.0094
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0058 0.0034 0.0034
Brugia malayi G-protein coupled receptor 0.0167 0.0114 0.0114
Onchocerca volvulus 0.0167 0.0114 0.0314
Onchocerca volvulus 0.0021 0.0007 0.0019
Echinococcus multilocularis neuropeptides capa receptor 0.0167 0.0114 0.0316
Schistosoma mansoni hypothetical protein 0.0082 0.0051 0.0142
Echinococcus multilocularis musashi 0.0025 0.001 0.0029
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0167 0.0114 0.0316
Brugia malayi Cytochrome P450 family protein 0.002 0.0007 0.0007
Onchocerca volvulus 0.0167 0.0114 0.0314
Loa Loa (eye worm) hypothetical protein 0.0065 0.004 0.004
Onchocerca volvulus 0.0151 0.0102 0.0281
Mycobacterium tuberculosis Probable dehydrogenase 0.019 0.013 0.0356
Loa Loa (eye worm) hypothetical protein 0.0012 0.0001 0.0001
Leishmania major hypothetical protein, conserved 0.0151 0.0102 0.0102
Loa Loa (eye worm) hypothetical protein 1.3771 1 1
Plasmodium vivax amine transporter, putative 0.0058 0.0034 0.0484
Loa Loa (eye worm) hypothetical protein 0.0021 0.0007 0.0007
Echinococcus granulosus glutamate receptor ionotropic kainate 0.0325 0.0228 0.0636
Loa Loa (eye worm) hypothetical protein 0.0167 0.0114 0.0114
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0021 0.0007 0.002
Trypanosoma brucei trypanothione reductase 0.0083 0.0052 0.0052
Loa Loa (eye worm) hypothetical protein 0.0339 0.0238 0.0238
Loa Loa (eye worm) hypothetical protein 0.0167 0.0114 0.0114
Loa Loa (eye worm) hypothetical protein 0.0012 0.0001 0.0001
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0021 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0021 0.0007 0.0007
Echinococcus multilocularis cpg binding protein 0.003 0.0014 0.0038
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0073 0.0045 0.0125
Trypanosoma brucei protein kinase, putative 0.0053 0.0031 0.0031
Plasmodium falciparum M1-family alanyl aminopeptidase 0.0541 0.0385 0.5613
Schistosoma mansoni voltage-gated potassium channel 0.0015 0.0003 0.0008
Brugia malayi Patched family protein 0.0012 0.0001 0.0001
Echinococcus multilocularis rhodopsin orphan GPCR 0.0167 0.0114 0.0316
Schistosoma mansoni Protoporphyrinogen oxidase chloroplast/mitochondrial precursor 0.0381 0.0269 0.0747
Mycobacterium tuberculosis 3-oxoacyl-[acyl-carrier-protein] synthase III FabH (beta-ketoacyl-ACP synthase III) (KAS III) 0.0954 0.0685 0.1882
Entamoeba histolytica fatty acid elongase, putative 0.0124 0.0082 0.5839
Brugia malayi hypothetical protein 0.0016 0.0004 0.0004
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.001 0.001
Plasmodium falciparum lysine-specific histone demethylase 1, putative 0.0381 0.0269 0.3912
Echinococcus multilocularis acetylcholinesterase 0.0063 0.0038 0.0106
Loa Loa (eye worm) hypothetical protein 0.0077 0.0048 0.0048
Loa Loa (eye worm) G-protein coupled receptor 0.0167 0.0114 0.0114
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0091 0.0058 0.0162
Onchocerca volvulus 0.0167 0.0114 0.0314
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0015 0.0003 0.0008
Loa Loa (eye worm) cytochrome P450 family protein 0.002 0.0007 0.0007
Trichomonas vaginalis CMGC family protein kinase 0.0053 0.0031 0.2811
Schistosoma mansoni amine GPCR 0.0513 0.0365 0.1015
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0091 0.0058 0.0058
Trypanosoma cruzi trypanothione reductase, putative 0.0083 0.0052 0.0052
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0167 0.0114 0.0114
Mycobacterium tuberculosis Probable reductase 0.019 0.013 0.0356
Loa Loa (eye worm) hypothetical protein 0.0077 0.0048 0.0048
Toxoplasma gondii hypothetical protein 0.0012 0.0001 0.0016
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0021 0.0007 0.0021
Echinococcus granulosus lipoxygenase domain containing protein 0.0021 0.0007 0.0019
Echinococcus multilocularis NMDA receptor 0.0325 0.0228 0.0636
Echinococcus multilocularis neuropeptide Y receptor 0.0167 0.0114 0.0316
Mycobacterium leprae PROBABLE PROTOPORPHYRINOGEN OXIDASE HEMY (PROTOPORPHYRINOGEN-IX OXIDASE) (PROTOPORPHYRINOGENASE) (PPO) 0.0381 0.0269 1
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0016 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0021 0.0007 0.0007
Echinococcus granulosus metabotropic glutamate receptor 2 0.0077 0.0048 0.0133
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0029 0.0013 0.0013
Echinococcus multilocularis neuropeptide s receptor 0.0167 0.0114 0.0316
Echinococcus multilocularis protein patched 0.0085 0.0053 0.0149
Brugia malayi RNA binding protein 0.0189 0.0129 0.0129
Brugia malayi Patched family protein 0.0012 0.0001 0.0001
Onchocerca volvulus 0.0013 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0012 0.0001 0.0001
Onchocerca volvulus 0.0021 0.0007 0.0018
Echinococcus multilocularis fmrfamide receptor 0.0167 0.0114 0.0316
Loa Loa (eye worm) patched family protein 0.0012 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0339 0.0238 0.0238
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0852 0.0611 0.17
Brugia malayi Kringle domain containing protein 0.0041 0.0022 0.0022
Echinococcus multilocularis G-protein coupled receptor, putative 0.0167 0.0114 0.0316
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.019 0.013 0.0356
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0029 0.0013 0.0033
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0021 0.0007 0.002
Loa Loa (eye worm) hypothetical protein 0.0012 0.0001 0.0001
Brugia malayi amine oxidase, flavin-containing family protein 0.0381 0.0269 0.0269
Brugia malayi Patched family protein 0.0012 0.0001 0.0001
Echinococcus granulosus acetylcholinesterase 0.0063 0.0038 0.0106
Brugia malayi hypothetical protein 0.0012 0.0001 0.0001
Echinococcus multilocularis beta LACTamase domain containing family member 0.0151 0.0102 0.0283
Schistosoma mansoni netrin receptor unc5 0.0015 0.0003 0.0008
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0021 0.0007 0.0021
Mycobacterium ulcerans aminopeptidase N PepN 0.0021 0.0007 0.0019
Schistosoma mansoni protein kinase 0.0079 0.0049 0.0136
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.0003 0.0086
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0151 0.0102 0.0102
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0029 0.0013 0.0013
Trypanosoma brucei cytochrome P450, putative 0.002 0.0007 0.0007
Brugia malayi MAP kinase sur-1 0.0053 0.0031 0.0031
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0029 0.0013 0.0013
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0091 0.0058 0.0162
Echinococcus granulosus serotonin receptor 0.0167 0.0114 0.0316
Brugia malayi isocitrate dehydrogenase 0.0016 0.0003 0.0003
Onchocerca volvulus 0.0025 0.001 0.0027
Echinococcus multilocularis lipoxygenase domain containing protein 0.0021 0.0007 0.0019
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0167 0.0114 0.0316
Brugia malayi Glutamate receptor 2 precursor 0.0775 0.0555 0.0555
Schistosoma mansoni ATP-binding cassette transporter 0.0775 0.0555 0.1545
Loa Loa (eye worm) hypothetical protein 0.0167 0.0114 0.0114
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.0021 0.0007 0.0472
Echinococcus multilocularis sterol regulatory element binding protein 0.0085 0.0053 0.0149
Echinococcus granulosus 7TM GPCR rhodopsin 0.0167 0.0114 0.0316
Loa Loa (eye worm) hypothetical protein 0.0012 0.0001 0.0001
Brugia malayi hypothetical protein 0.0167 0.0114 0.0114
Echinococcus multilocularis nmda type glutamate receptor 0.0717 0.0513 0.1427
Loa Loa (eye worm) hypothetical protein 0.0012 0.0001 0.0001
Brugia malayi Isocitrate dehydrogenase 0.0016 0.0003 0.0003
Loa Loa (eye worm) glutamate receptor 0.0077 0.0048 0.0048
Brugia malayi Patched family protein 0.0012 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0167 0.0114 0.0114
Trichomonas vaginalis penicillin-binding protein, putative 0.0151 0.0102 1
Loa Loa (eye worm) hypothetical protein 0.0012 0.0001 0.0001
Echinococcus multilocularis expressed conserved protein 0.0185 0.0126 0.0352
Echinococcus granulosus nmda type glutamate receptor 0.0717 0.0513 0.1427
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0058 0.0034 0.0094
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.019 0.013 0.4832
Schistosoma mansoni tyrosine kinase 0.0093 0.006 0.0166
Echinococcus granulosus sodium and chloride dependent glycine 0.0058 0.0034 0.0094
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0021 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0015 0.0003 0.0003
Trichomonas vaginalis CMGC family protein kinase 0.0053 0.0031 0.2811
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0167 0.0114 0.0114
Plasmodium vivax protoporphyrinogen oxidase, putative 0.0381 0.0269 0.3912
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0053 0.0031 0.0031
Echinococcus multilocularis Ribosomal protein S1, RNA binding domain 0.0325 0.0228 0.0636
Loa Loa (eye worm) hypothetical protein 0.1848 0.1335 0.1335
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0021 0.0007 0.0007
Echinococcus multilocularis acetylcholinesterase 0.0063 0.0038 0.0106
Schistosoma mansoni sodium-dependent amino acid transporter 0.0058 0.0034 0.0094
Trypanosoma cruzi hypothetical protein, conserved 0.0041 0.0022 0.0022
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0021 0.0007 0.002
Onchocerca volvulus Neuropeptide F receptor homolog 0.0167 0.0114 0.0314
Mycobacterium tuberculosis Probable lipase LipD 0.0151 0.0102 0.0279
Loa Loa (eye worm) hypothetical protein 0.0381 0.0269 0.0269
Brugia malayi Tachykinin-like peptides receptor 99D 0.0167 0.0114 0.0114
Loa Loa (eye worm) vesicular acetylcholine transporter unc-17 0.4955 0.3593 0.3593
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0021 0.0007 0.0007
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0058 0.0034 0.0094
Onchocerca volvulus 0.0058 0.0034 0.0092
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0016 0.0003 0.0009
Echinococcus multilocularis Polycystic kidney disease protein 0.0021 0.0007 0.0019
Mycobacterium ulcerans beta-ketoacyl synthase-like protein 0.0954 0.0685 0.1749
Loa Loa (eye worm) glutamate receptor 2 0.0775 0.0555 0.0555
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0007 0.002
Echinococcus granulosus Ribosomal protein S1 RNA binding domain 0.0325 0.0228 0.0636
Loa Loa (eye worm) metabotropic GABA-B receptor subtype 2 0.0077 0.0048 0.0048
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0075 0.0047 0.0047
Schistosoma mansoni hypothetical protein 0.0073 0.0045 0.0125
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.019 0.013 0.0356
Brugia malayi metabotropic glutamate receptor type 2 0.0077 0.0048 0.0048
Brugia malayi protein C24B5.3 0.0012 0.0001 0.0001
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0053 0.0031 0.0031
Echinococcus granulosus epidermal growth factor receptor 0.0292 0.0204 0.0568
Schistosoma mansoni P2X receptor subunit 0.0033 0.0016 0.0044
Onchocerca volvulus 0.0167 0.0114 0.0314
Echinococcus granulosus fatty acid amide hydrolase 1 0.0076 0.0047 0.0131
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0058 0.0034 0.0094
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0075 0.0047 0.013
Loa Loa (eye worm) hypothetical protein 0.0012 0.0001 0.0001
Echinococcus granulosus nmda type glutamate receptor 0.0311 0.0218 0.0606
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0007 0.0007
Onchocerca volvulus 0.0167 0.0114 0.0314
Schistosoma mansoni glutamate receptor AMPA 0.0775 0.0555 0.1545
Plasmodium falciparum beta-ketoacyl-ACP synthase III 0.0954 0.0685 1
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0211 0.0145 0.5404
Brugia malayi Dopamine receptor protein 2 0.0167 0.0114 0.0114
Echinococcus multilocularis sodium and chloride dependent glycine 0.0058 0.0034 0.0094
Mycobacterium ulcerans esterase/lipase LipP 0.0151 0.0102 0.026
Schistosoma mansoni tyrosine kinase 0.0093 0.006 0.0166
Treponema pallidum sodium- and chloride- dependent transporter 0.0339 0.0238 1
Schistosoma mansoni vesicular acetylcholine transporter 0.4955 0.3593 1
Trypanosoma cruzi aminopeptidase, putative 0.0021 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0167 0.0114 0.0114
Mycobacterium ulcerans 3-oxoacyl-ACP synthase 0.0954 0.0685 0.1749
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0021 0.0007 0.002
Loa Loa (eye worm) hypothetical protein 0.0021 0.0007 0.0007
Leishmania major UDP-galactopyranose mutase 0.0381 0.0269 0.0269
Brugia malayi Peptidase family M1 containing protein 0.0021 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0012 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0012 0.0001 0.0001
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0021 0.0007 0.0007
Onchocerca volvulus 0.0167 0.0114 0.0314
Brugia malayi Patched family protein 0.0012 0.0001 0.0001
Echinococcus granulosus receptor type guanylyl cyclase 0.0079 0.0049 0.0136
Echinococcus granulosus alpha 1A adrenergic receptor 0.0167 0.0114 0.0316
Loa Loa (eye worm) hypothetical protein 0.0058 0.0034 0.0034
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0075 0.0047 0.0047
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0083 0.0052 0.0144
Schistosoma mansoni voltage-gated potassium channel 0.0022 0.0008 0.0022
Echinococcus multilocularis tissue type plasminogen activator 0.0041 0.0022 0.0061
Loa Loa (eye worm) hypothetical protein 0.0151 0.0102 0.0102
Plasmodium vivax lysine-specific histone demethylase 1, putative 0.0381 0.0269 0.3912
Loa Loa (eye worm) TAR-binding protein 0.0189 0.0129 0.0129
Brugia malayi Doublecortin family protein 0.0021 0.0007 0.0007
Brugia malayi Furin-like cysteine rich region family protein 0.0292 0.0204 0.0204
Loa Loa (eye worm) hypothetical protein 0.0058 0.0034 0.0034
Onchocerca volvulus Protein ultraspiracle homolog 0.0021 0.0007 0.0018
Loa Loa (eye worm) aminopeptidase N 0.0021 0.0007 0.0007
Schistosoma mansoni cpg binding protein 0.0028 0.0013 0.0035
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0007 0.0007
Brugia malayi Latrophilin receptor protein 2 0.0073 0.0045 0.0045
Brugia malayi hypothetical protein 0.0021 0.0007 0.0007
Echinococcus multilocularis rhodopsin orphan GPCR 0.0167 0.0114 0.0316
Brugia malayi Metabotropic glutamate receptor precursor. 0.0077 0.0048 0.0048
Brugia malayi sulfakinin receptor protein 0.0167 0.0114 0.0114
Schistosoma mansoni P2X receptor subunit 0.0033 0.0016 0.0044
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0015 0.0003 0.0008
Schistosoma mansoni neuropeptide F-like receptor 0.0167 0.0114 0.0316
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0029 0.0013 0.0036
Echinococcus granulosus rhodopsin orphan GPCR 0.0167 0.0114 0.0316
Trypanosoma brucei metallo-peptidase, Clan MA(E) Family M1 0.0021 0.0007 0.0007
Brugia malayi ORL1-like opioid receptor 0.0167 0.0114 0.0114
Brugia malayi Cytochrome P450 family protein 0.002 0.0007 0.0007
Schistosoma mansoni voltage-gated potassium channel 0.0082 0.0052 0.0144
Echinococcus granulosus expressed conserved protein 0.0185 0.0126 0.0352
Schistosoma mansoni amine GPCR 0.0167 0.0114 0.0316
Brugia malayi hypothetical protein 0.0167 0.0114 0.0114
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0073 0.0045 0.0125
Schistosoma mansoni mixed-lineage leukemia protein mll 0.006 0.0036 0.01
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.0003 0.0086
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0085 0.0053 0.0053
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0058 0.0034 0.0094
Echinococcus multilocularis sex peptide receptor 0.0167 0.0114 0.0316
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0167 0.0114 0.0316
Plasmodium vivax hypothetical protein, conserved 0.0058 0.0034 0.0484
Schistosoma mansoni cytosol alanyl aminopeptidase (M01 family) 0.0021 0.0007 0.0021
Echinococcus multilocularis fatty acid amide hydrolase 1 0.0076 0.0047 0.0131
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0021 0.0007 0.002
Loa Loa (eye worm) solute carrier family 6 member 4 0.0339 0.0238 0.0238
Schistosoma mansoni amine GPCR 0.0167 0.0114 0.0316
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0021 0.0007 0.002
Brugia malayi RNA recognition motif domain containing protein 0.0189 0.0129 0.0129
Loa Loa (eye worm) leukotriene A4 hydrolase 0.0021 0.0007 0.0007
Schistosoma mansoni sodium/chloride dependent transporter 0.0058 0.0034 0.0095
Onchocerca volvulus 0.0151 0.0102 0.0281
Echinococcus granulosus death domain containing protein 0.0015 0.0003 0.0008
Brugia malayi Death domain containing protein 0.0015 0.0003 0.0003
Echinococcus multilocularis thioredoxin glutathione reductase 0.0084 0.0053 0.0147
Brugia malayi hypothetical protein 0.0167 0.0114 0.0114
Loa Loa (eye worm) hypothetical protein 0.0167 0.0114 0.0114
Brugia malayi vesicular acetylcholine transporter unc-17 0.4955 0.3593 0.3593
Echinococcus multilocularis rhodopsin orphan GPCR 0.0167 0.0114 0.0316
Echinococcus multilocularis hyperpolarization activated cyclic 0.0015 0.0003 0.0008
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0021 0.0007 0.0007
Wolbachia endosymbiont of Brugia malayi 3-oxoacyl-ACP synthase 0.0954 0.0685 1
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0053 0.0031 0.0031
Brugia malayi Niemann-Pick C1 protein precursor 0.0197 0.0135 0.0135
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0016 0.0003 0.0009
Loa Loa (eye worm) hypothetical protein 0.0167 0.0114 0.0114
Entamoeba histolytica fatty acid elongase, putative 0.0124 0.0082 0.5839
Echinococcus granulosus vesicular acetylcholine transporter 0.4955 0.3593 1
Schistosoma mansoni glutamate receptor kainate 0.0775 0.0555 0.1545
Echinococcus granulosus leukotriene A 4 hydrolase 0.0021 0.0007 0.0021
Loa Loa (eye worm) G-protein coupled receptor 0.0167 0.0114 0.0114
Echinococcus granulosus glutamate receptor 2 0.0852 0.0611 0.17
Trypanosoma brucei hypothetical protein, conserved 0.0151 0.0102 0.0102
Loa Loa (eye worm) hypothetical protein 0.0077 0.0048 0.0048
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0003 0.0009
Mycobacterium ulcerans beta-lactamase 0.0151 0.0102 0.026
Echinococcus multilocularis allatostatin A receptor 0.0167 0.0114 0.0316
Onchocerca volvulus 0.0028 0.0013 0.0033
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0022 0.0008 0.0022
Brugia malayi Patched related family protein 4 0.0012 0.0001 0.0001
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0029 0.0013 0.0179
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0007 0.002
Brugia malayi hypothetical protein 0.0167 0.0114 0.0114
Loa Loa (eye worm) hypothetical protein 0.0022 0.0008 0.0008
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.001 0.0256
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0167 0.0114 0.0316
Trypanosoma cruzi C-8 sterol isomerase, putative 1.3771 1 1
Onchocerca volvulus 0.0167 0.0114 0.0314
Toxoplasma gondii aminopeptidase n, putative 0.0541 0.0385 1
Brugia malayi Glutamate receptor 1 precursor 0.0775 0.0555 0.0555
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0029 0.0013 0.0013
Echinococcus granulosus neuropeptide Y receptor 0.0167 0.0114 0.0316
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0029 0.0013 0.0013
Plasmodium falciparum thioredoxin reductase 0.0029 0.0013 0.0179
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0075 0.0047 0.013
Brugia malayi Immunoglobulin I-set domain containing protein 0.0015 0.0003 0.0003
Mycobacterium tuberculosis Probable glutamine-binding lipoprotein GlnH (GLNBP) 0.0157 0.0106 0.0291
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.1547 0.1116 0.3107
Echinococcus granulosus lamin 0.0025 0.001 0.0029
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0167 0.0114 0.0316
Loa Loa (eye worm) hypothetical protein 0.0012 0.0001 0.0001
Echinococcus granulosus g protein coupled receptor 0.0167 0.0114 0.0316
Schistosoma mansoni neuropeptide receptor 0.0167 0.0114 0.0316
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0021 0.0007 0.0007
Loa Loa (eye worm) TK/INSR protein kinase 0.0093 0.006 0.006
Loa Loa (eye worm) hypothetical protein 0.0167 0.0114 0.0114
Loa Loa (eye worm) hypothetical protein 0.0167 0.0114 0.0114
Echinococcus granulosus acetylcholinesterase 0.0063 0.0038 0.0106
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0007 0.002
Trypanosoma brucei Aminopeptidase M1, putative 0.0021 0.0007 0.0007
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0167 0.0114 0.0316
Brugia malayi hypothetical protein 0.0021 0.0007 0.0007
Toxoplasma gondii NADPH-glutathione reductase 0.0029 0.0013 0.0334
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0053 0.0031 0.0031
Echinococcus multilocularis neuropeptide receptor 0.0167 0.0114 0.0316
Plasmodium vivax glutathione reductase, putative 0.0083 0.0052 0.0755
Mycobacterium tuberculosis Possible oxidoreductase 0.0381 0.0269 0.0737
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0021 0.0007 0.0007
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0077 0.0048 0.0048
Echinococcus granulosus Niemann Pick C1 protein 0.0197 0.0135 0.0376
Echinococcus multilocularis neuropeptides capa receptor 0.0167 0.0114 0.0316
Brugia malayi Patched family protein 0.0012 0.0001 0.0001
Schistosoma mansoni hypothetical protein 0.0041 0.0022 0.0061
Echinococcus granulosus allatostatin A receptor 0.0167 0.0114 0.0316
Onchocerca volvulus 0.0077 0.0048 0.0131
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0151 0.0102 0.0279
Loa Loa (eye worm) hypothetical protein 0.0012 0.0001 0.0001
Schistosoma mansoni amine oxidase 0.0381 0.0269 0.0747
Echinococcus granulosus glutamate receptor 2 0.0526 0.0374 0.1042
Schistosoma mansoni tar DNA-binding protein 0.0189 0.0129 0.036
Echinococcus multilocularis ecdysone induced protein 78C 0.0021 0.0007 0.002
Onchocerca volvulus 0.0013 0.0001 0.0001
Mycobacterium ulcerans monoamine oxidase 0.0381 0.0269 0.0685
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0167 0.0114 0.0316
Echinococcus multilocularis epidermal growth factor receptor 0.0157 0.0106 0.0295
Schistosoma mansoni hypothetical protein 0.0405 0.0286 0.0797
Schistosoma mansoni hypothetical protein 0.0325 0.0228 0.0636
Brugia malayi hypothetical protein 0.0167 0.0114 0.0114
Schistosoma mansoni cpg binding protein 0.003 0.0014 0.0038
Plasmodium vivax M1-family alanyl aminopeptidase, putative 0.0021 0.0007 0.01
Schistosoma mansoni glutamate receptor kainate 0.0775 0.0555 0.1545
Schistosoma mansoni fatty-acid amide hydrolase 0.0076 0.0047 0.0131
Echinococcus multilocularis mitogen activated protein kinase 3 0.0053 0.0031 0.0085
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0167 0.0114 0.0316
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0091 0.0058 0.0162
Trypanosoma cruzi puromycin-sensitive aminopeptidase-like protein, putative 0.0021 0.0007 0.0007
Echinococcus granulosus lipoxygenase domain containing protein 0.0021 0.0007 0.0019
Loa Loa (eye worm) hypothetical protein 0.0167 0.0114 0.0114
Echinococcus granulosus glutamate receptor subunit protein glur 0.0325 0.0228 0.0636
Brugia malayi hypothetical protein 0.0167 0.0114 0.0114
Echinococcus multilocularis FTZ F1 alpha 0.0021 0.0007 0.002
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0021 0.0007 0.002
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.001 0.001
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0123 0.0081 0.0227
Brugia malayi Patched related family protein 10 0.0012 0.0001 0.0001
Schistosoma mansoni voltage-gated potassium channel 0.0022 0.0008 0.0022
Plasmodium vivax hypothetical protein, conserved 0.0381 0.0269 0.3912
Loa Loa (eye worm) patched family protein 0.0012 0.0001 0.0001
Echinococcus multilocularis g protein coupled receptor 0.0167 0.0114 0.0316
Echinococcus granulosus rhodopsin orphan GPCR 0.0167 0.0114 0.0316
Schistosoma mansoni hypothetical protein 0.0073 0.0045 0.0125
Loa Loa (eye worm) patched family protein 0.0012 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0058 0.0034 0.0034
Loa Loa (eye worm) patched family protein 0.0012 0.0001 0.0001
Trypanosoma cruzi metallo-peptidase, clan MA(E), family M1, putative 0.0021 0.0007 0.0007
Brugia malayi follicle stimulating hormone receptor 0.0167 0.0114 0.0114
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0058 0.0034 0.0094
Echinococcus multilocularis conserved hypothetical protein 0.0669 0.0478 0.1331
Loa Loa (eye worm) hypothetical protein 0.0167 0.0114 0.0114
Echinococcus multilocularis p2X purinoceptor 4 0.0033 0.0016 0.0044
Schistosoma mansoni voltage-gated potassium channel 0.0012 0.0001 0.0002
Mycobacterium tuberculosis Probable conserved transmembrane transport protein 0.0015 0.0003 0.0007
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0167 0.0114 0.0114
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0021 0.0007 0.0007
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.001 0.0135
Schistosoma mansoni hypothetical protein 0.0073 0.0045 0.0125
Echinococcus granulosus RUN 0.0021 0.0007 0.0019
Echinococcus granulosus GPCR family 2 0.0073 0.0045 0.0125
Loa Loa (eye worm) hypothetical protein 0.7038 0.5107 0.5107
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0167 0.0114 0.0316
Loa Loa (eye worm) hypothetical protein 0.0167 0.0114 0.0114
Loa Loa (eye worm) hypothetical protein 0.0167 0.0114 0.0114
Loa Loa (eye worm) hypothetical protein 0.0167 0.0114 0.0114
Echinococcus granulosus hyperpolarization activated cyclic 0.0015 0.0003 0.0008
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0077 0.0048 0.0133
Loa Loa (eye worm) hypothetical protein 0.0021 0.0007 0.0007
Schistosoma mansoni lipoxygenase 0.0123 0.0081 0.0227
Schistosoma mansoni opsin-like receptor 0.0167 0.0114 0.0316
Onchocerca volvulus 0.0021 0.0007 0.0019
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0021 0.0007 0.0007
Echinococcus granulosus p2X purinoceptor 4 0.0033 0.0016 0.0044
Loa Loa (eye worm) hypothetical protein 0.0021 0.0007 0.0007
Echinococcus granulosus tissue type plasminogen activator 0.0041 0.0022 0.0061
Loa Loa (eye worm) hypothetical protein 0.0167 0.0114 0.0114
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0211 0.0145 0.0398
Echinococcus multilocularis dnaJ subfamily B 0.0405 0.0286 0.0797
Loa Loa (eye worm) TK/ROR protein kinase 0.0043 0.0023 0.0023
Loa Loa (eye worm) thioredoxin reductase 0.0083 0.0052 0.0052
Brugia malayi steroid hormone receptor 0.0021 0.0007 0.0007
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0211 0.0145 0.0398
Echinococcus granulosus tyrosine kinase 0.0079 0.0049 0.0136
Echinococcus multilocularis serotonin transporter 0.0339 0.0238 0.0663
Mycobacterium tuberculosis Probable oxidoreductase 0.0211 0.0145 0.0398
Brugia malayi Patched family protein 0.0012 0.0001 0.0001
Schistosoma mansoni glutamate receptor kainate 0.0775 0.0555 0.1545
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0015 0.0003 0.0008
Toxoplasma gondii thioredoxin reductase 0.0083 0.0052 0.136
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0021 0.0007 0.0007
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0021 0.0007 0.0021
Leishmania major aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 0.0021 0.0007 0.0007
Echinococcus multilocularis fatty acid amide hydrolase 1 0.0076 0.0047 0.0131
Leishmania major puromycin-sensitive aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 0.0021 0.0007 0.0007
Echinococcus multilocularis nmda type glutamate receptor 0.0311 0.0218 0.0606
Loa Loa (eye worm) hypothetical protein 0.0158 0.0106 0.0106
Brugia malayi Cyclic-nucleotide gated cation channel 0.0015 0.0003 0.0003
Echinococcus multilocularis voltage gated potassium channel 0.0022 0.0008 0.0022
Echinococcus multilocularis dro:myosuppressin receptor 0.0167 0.0114 0.0316
Echinococcus multilocularis p2X purinoceptor 4 0.0033 0.0016 0.0044
Onchocerca volvulus 0.0167 0.0114 0.0314
Loa Loa (eye worm) hypothetical protein 0.0012 0.0001 0.0001
Loa Loa (eye worm) steroid hormone receptor 0.0021 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0012 0.0001 0.0001
Brugia malayi nuclear receptor RXR 0.0011 0.0000040859 0.0000027371
Schistosoma mansoni amidase 0.0076 0.0047 0.0131
Schistosoma mansoni lamin 0.0025 0.001 0.0029
Schistosoma mansoni hypothetical protein 0.0158 0.0106 0.0296
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0029 0.0013 0.0013
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0058 0.0034 0.0311
Brugia malayi SWIRM domain containing protein 0.0381 0.0269 0.0269
Brugia malayi hypothetical protein 0.0021 0.0007 0.0007
Plasmodium falciparum glutathione reductase 0.0029 0.0013 0.0179
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0058 0.0034 0.0094
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0167 0.0114 0.0316
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0167 0.0114 0.0316
Brugia malayi Guanylyl cyclase protein 23 0.0079 0.0049 0.0049
Mycobacterium ulcerans glutamine-binding lipoprotein GlnH 0.0157 0.0106 0.0271
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0058 0.0034 0.0094
Echinococcus granulosus rhodopsin orphan GPCR 0.0167 0.0114 0.0316
Onchocerca volvulus 0.0167 0.0114 0.0314
Onchocerca volvulus 0.0041 0.0022 0.006
Echinococcus granulosus serotonin transporter 0.0339 0.0238 0.0663
Loa Loa (eye worm) hypothetical protein 0.0381 0.0269 0.0269
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0021 0.0007 0.0021
Entamoeba histolytica fatty acid elongase, putative 0.0124 0.0082 0.5839
Brugia malayi Thioredoxin reductase 0.0083 0.0052 0.0052
Loa Loa (eye worm) hypothetical protein 0.0076 0.0047 0.0047
Loa Loa (eye worm) hypothetical protein 0.0167 0.0114 0.0114
Echinococcus granulosus mitogen activated protein kinase 0.0053 0.0031 0.0085
Loa Loa (eye worm) hypothetical protein 0.0079 0.0049 0.0049
Loa Loa (eye worm) hypothetical protein 0.0012 0.0001 0.0001
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0029 0.0013 0.0013
Schistosoma mansoni niemann-pick C1 (NPC1) 0.02 0.0137 0.0382
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0381 0.0269 0.3912
Brugia malayi hypothetical protein 0.0011 0.0000040859 0.0000027371
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0029 0.0013 0.0013
Echinococcus multilocularis serotonin receptor 0.1848 0.1335 0.3715
Toxoplasma gondii aminopeptidase N, putative 0.0541 0.0385 1
Chlamydia trachomatis protoporphyrinogen oxidase 0.0381 0.0269 0.3801
Echinococcus multilocularis glutamate receptor NMDA 0.0234 0.0162 0.0451
Toxoplasma gondii hypothetical protein 0.0058 0.0034 0.0877
Schistosoma mansoni hypothetical protein 0.0015 0.0003 0.0008
Loa Loa (eye worm) hypothetical protein 0.0063 0.0038 0.0038
Brugia malayi larval opioid receptor 0.0167 0.0114 0.0114
Loa Loa (eye worm) CYP4Cod1 0.002 0.0007 0.0007
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0021 0.0007 0.0007
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0167 0.0114 0.0316
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0021 0.0007 0.0021
Echinococcus granulosus mitogen activated protein kinase 3 0.0053 0.0031 0.0085
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0021 0.0007 0.002
Loa Loa (eye worm) hypothetical protein 0.0011 0.0000040859 0.0000027371
Loa Loa (eye worm) hypothetical protein 0.0167 0.0114 0.0114
Loa Loa (eye worm) hypothetical protein 0.0167 0.0114 0.0114
Loa Loa (eye worm) hypothetical protein 0.0167 0.0114 0.0114
Echinococcus granulosus Polycystic kidney disease protein 0.0021 0.0007 0.0019
Echinococcus granulosus 7tm_1 domain containing protein 0.0167 0.0114 0.0316
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0015 0.0003 0.0008
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0167 0.0114 0.0316
Echinococcus multilocularis neuropeptide receptor A26 0.0167 0.0114 0.0316
Echinococcus granulosus glutamate receptor NMDA 0.0234 0.0162 0.0451
Echinococcus granulosus G protein coupled receptor 139 0.0167 0.0114 0.0316
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0167 0.0114 0.0316
Schistosoma mansoni tar DNA-binding protein 0.0189 0.0129 0.036
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0012 0.0001 0.0002
Schistosoma mansoni hypothetical protein 0.0167 0.0114 0.0316
Schistosoma mansoni amine GPCR 0.0167 0.0114 0.0316
Brugia malayi beta-lactamase 0.0151 0.0102 0.0102
Brugia malayi photoreceptor-specific nuclear receptor 0.0021 0.0007 0.0007
Leishmania major hypothetical protein, conserved 0.0025 0.001 0.001
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0197 0.0135 1
Loa Loa (eye worm) receptor family ligand binding region containing protein 0.0077 0.0048 0.0048
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0091 0.0058 0.0162
Echinococcus multilocularis glutamate receptor subunit protein glur 0.0325 0.0228 0.0636
Trichomonas vaginalis D-aminoacylase, putative 0.0151 0.0102 1
Loa Loa (eye worm) hypothetical protein 0.0167 0.0114 0.0114
Echinococcus multilocularis 0.009 0.0058 0.0161
Brugia malayi Muscle positioning protein 4 0.0016 0.0003 0.0003
Mycobacterium tuberculosis Conserved hypothetical protein 0.0381 0.0269 0.0737
Echinococcus multilocularis g protein coupled receptor 0.0167 0.0114 0.0316
Trypanosoma cruzi extracellular receptor, putative 0.0077 0.0048 0.0048
Onchocerca volvulus 0.0025 0.001 0.0027
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0167 0.0114 0.0316
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0029 0.0013 0.0013
Mycobacterium ulcerans aminopeptidase N PepN 0.0021 0.0007 0.0019
Brugia malayi CHE-14 protein 0.0085 0.0053 0.0053
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0014 0.0002 0.0002
Echinococcus granulosus peptide allatostatin:somatostatin 0.0167 0.0114 0.0316
Echinococcus multilocularis neuropeptide receptor 0.0167 0.0114 0.0316
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0015 0.0003 0.0008
Loa Loa (eye worm) RGC/RGC protein kinase 0.0079 0.0049 0.0049
Echinococcus granulosus p2X purinoceptor 4 0.0033 0.0016 0.0044
Loa Loa (eye worm) hypothetical protein 0.0077 0.0048 0.0048
Echinococcus multilocularis Peptidase M1, membrane alanine aminopeptidase, N terminal 0.0021 0.0007 0.0021
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0053 0.0031 0.0031
Brugia malayi hypothetical protein 0.0167 0.0114 0.0114
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0015 0.0003 0.0008
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 0.0021 0.0007 0.0007
Chlamydia trachomatis oxoacyl-ACP synthase III 0.0954 0.0685 1
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0003 0.0009
Schistosoma mansoni biogenic amine (5HT) receptor 0.1848 0.1335 0.3715
Onchocerca volvulus 0.0167 0.0114 0.0314
Echinococcus granulosus Protein patched homolog 1 0.0085 0.0053 0.0149
Loa Loa (eye worm) hypothetical protein 0.0085 0.0053 0.0053
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0013 0.0002 0.0005
Echinococcus granulosus Niemann Pick C1 protein 0.0282 0.0197 0.0547
Schistosoma mansoni thyroid hormone receptor 0.0021 0.0007 0.002
Toxoplasma gondii histone lysine-specific demethylase LSD1/BHC110/KDMA1A 0.0382 0.027 0.7006
Echinococcus granulosus sodium and chloride dependent glycine 0.0058 0.0034 0.0094
Loa Loa (eye worm) melatonin receptor type 1A 0.0167 0.0114 0.0114
Echinococcus multilocularis lipoxygenase domain containing protein 0.0021 0.0007 0.0019
Loa Loa (eye worm) neuropeptide F receptor 0.0167 0.0114 0.0114
Onchocerca volvulus 0.0167 0.0114 0.0314
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0029 0.0013 0.0013
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0029 0.0013 0.0013
Trichomonas vaginalis CMGC family protein kinase 0.0053 0.0031 0.2811
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0021 0.0007 0.0007
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0091 0.0058 0.0162
Echinococcus granulosus hyperpolarization activated cyclic 0.0015 0.0003 0.0008
Schistosoma mansoni sodium/chloride dependent transporter 0.0339 0.0238 0.0663
Onchocerca volvulus 0.0021 0.0007 0.0019
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0167 0.0114 0.0316
Echinococcus multilocularis orexin receptor type 2 0.0167 0.0114 0.0316
Brugia malayi Patched related family protein 12 0.0012 0.0001 0.0001
Echinococcus granulosus tar DNA binding protein 0.0189 0.0129 0.036
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0157 0.0106 0.0295
Trypanosoma cruzi hypothetical protein, conserved 0.0151 0.0102 0.0102
Trypanosoma cruzi Aminopeptidase M1, putative 0.0021 0.0007 0.0007
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0021 0.0007 0.002
Echinococcus granulosus insulin receptor 0.0093 0.006 0.0166
Trypanosoma cruzi metallo-peptidase, Clan MA(E) Family M1 0.0021 0.0007 0.0007
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0013 0.0013
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0041 0.0022 0.0313
Loa Loa (eye worm) RGC/RGC protein kinase 0.0079 0.0049 0.0049
Schistosoma mansoni tyrosine kinase 0.0079 0.0049 0.0136
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0073 0.0045 0.0125
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0021 0.0007 0.002
Brugia malayi glutathione reductase 0.0083 0.0052 0.0052
Schistosoma mansoni hypothetical protein 0.0167 0.0114 0.0316
Entamoeba histolytica hypothetical protein 0.0077 0.0048 0.3161
Loa Loa (eye worm) acetylcholinesterase 1 0.0063 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.0012 0.0001 0.0001
Echinococcus granulosus tm gpcr rhodopsin 0.0167 0.0114 0.0316
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0167 0.0114 0.0316
Schistosoma mansoni amine GPCR 0.0167 0.0114 0.0316
Echinococcus granulosus intermediate filament protein 0.0025 0.001 0.0029
Trichomonas vaginalis mercuric reductase, putative 0.0029 0.0013 0.102
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.5404 0.3919 1
Loa Loa (eye worm) hypothetical protein 0.0381 0.0269 0.0269
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0053 0.0031 0.0795
Echinococcus multilocularis netrin receptor unc 5 0.0015 0.0003 0.0008
Mycobacterium ulcerans transmembrane transport protein 0.0015 0.0003 0.0006
Mycobacterium tuberculosis Probable hydrolase 0.0151 0.0102 0.0279
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0852 0.0611 0.17
Brugia malayi TATA binding protein associated factor 0.0021 0.0007 0.0007
Echinococcus multilocularis rhodopsin orphan GPCR 0.0167 0.0114 0.0316
Echinococcus granulosus orexin receptor type 2 0.0167 0.0114 0.0316
Schistosoma mansoni amine oxidase 0.0381 0.0269 0.0747
Loa Loa (eye worm) hypothetical protein 0.0151 0.0102 0.0102
Schistosoma mansoni lamin 0.0025 0.001 0.0029
Echinococcus multilocularis fmrfamide receptor 0.0167 0.0114 0.0316
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0167 0.0114 0.0316
Brugia malayi Protein kinase domain containing protein 0.0093 0.006 0.006
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0015 0.0003 0.0008
Brugia malayi hypothetical protein 0.0012 0.0001 0.0001
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0077 0.0048 0.0133
Echinococcus granulosus rhodopsin orphan GPCR 0.0167 0.0114 0.0316
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1616 0.1167 0.3247
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0011 0.0000040859 0.0000027371
Schistosoma mansoni tyrosine kinase 0.0292 0.0204 0.0568
Echinococcus granulosus neuropeptide Y receptor 0.0167 0.0114 0.0316
Schistosoma mansoni retinoic acid receptor RXR 0.0021 0.0007 0.002
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0029 0.0013 0.0013
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0668 0.0477 0.1328
Schistosoma mansoni rab6-interacting 0.0021 0.0007 0.0019
Echinococcus multilocularis metabotropic glutamate receptor 2 0.0077 0.0048 0.0133
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0073 0.0045 0.0125
Loa Loa (eye worm) hypothetical protein 0.0151 0.0102 0.0102
Loa Loa (eye worm) hypothetical protein 0.0013 0.0001 0.0001
Onchocerca volvulus 0.0167 0.0114 0.0314
Loa Loa (eye worm) hypothetical protein 0.0012 0.0001 0.0001
Schistosoma mansoni rab6-interacting 0.0021 0.0007 0.0019
Mycobacterium tuberculosis Putative ferredoxin reductase 0.019 0.013 0.0356
Echinococcus granulosus neuropeptide receptor 0.0167 0.0114 0.0316
Brugia malayi Nuclear hormone receptor-like 1 0.0011 0.0000040859 0.0000027371
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0016 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0381 0.0269 0.0269
Schistosoma mansoni intermediate filament proteins 0.0025 0.001 0.0029
Onchocerca volvulus 0.0167 0.0114 0.0314
Loa Loa (eye worm) hypothetical protein 0.0012 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0104 0.0067 0.0067
Schistosoma mansoni hypothetical protein 0.0507 0.0361 0.1004
Echinococcus multilocularis receptor type guanylyl cyclase 0.0079 0.0049 0.0136
Echinococcus granulosus tm gpcr rhodopsin 0.0167 0.0114 0.0316
Plasmodium vivax hypothetical protein, conserved 0.0381 0.0269 0.3912
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0015 0.0003 0.0008
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0003 0.0009
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0021 0.0007 0.0021
Mycobacterium tuberculosis Conserved protein 0.0151 0.0102 0.0279
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0167 0.0114 0.0316
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0029 0.0013 0.0334
Schistosoma mansoni biogenic amine receptor 0.0167 0.0114 0.0316
Schistosoma mansoni myosin xvIII 0.0167 0.0114 0.0316
Loa Loa (eye worm) hypothetical protein 0.0167 0.0114 0.0114
Onchocerca volvulus Bile acid receptor homolog 0.0021 0.0007 0.0018
Schistosoma mansoni P2X receptor subunit 0.0033 0.0016 0.0044
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0167 0.0114 0.0316
Brugia malayi putative neuropeptide receptor NPR1 0.0167 0.0114 0.0114
Toxoplasma gondii ABC1 family protein 0.0151 0.0102 0.2641
Loa Loa (eye worm) hypothetical protein 0.0151 0.0102 0.0102
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0015 0.0003 0.0008
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0029 0.0013 0.0036
Echinococcus granulosus fmrfamide receptor 0.0167 0.0114 0.0316
Mycobacterium ulcerans oxidoreductase 0.0381 0.0269 0.0685
Chlamydia trachomatis glutamine binding protein 0.0157 0.0106 0.1387
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0231 0.016 0.0159
Loa Loa (eye worm) DOMON domain-containing protein 0.0013 0.0001 0.0001
Schistosoma mansoni metabotropic glutamate receptor 0.0077 0.0048 0.0133
Schistosoma mansoni neuropeptide receptor 0.0167 0.0114 0.0316
Loa Loa (eye worm) hypothetical protein 0.0025 0.001 0.001
Echinococcus multilocularis lysine specific histone demethylase 1A 0.0381 0.0269 0.0747
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0852 0.0611 0.17
Echinococcus granulosus neuropeptide receptor A26 0.0167 0.0114 0.0316
Loa Loa (eye worm) hypothetical protein 0.0381 0.0269 0.0269
Brugia malayi CXXC zinc finger family protein 0.0028 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0041 0.0022 0.0022
Toxoplasma gondii kringle domain-containing protein 0.0041 0.0022 0.0572
Trypanosoma cruzi puromycin-sensitive aminopeptidase-like protein, putative 0.0021 0.0007 0.0007
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0058 0.0034 0.0034
Schistosoma mansoni cytochrome P450 0.0011 0.0000013488 0.0000037538
Loa Loa (eye worm) hypothetical protein 0.0012 0.0001 0.0001
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0016 0.0003 0.0009
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0021 0.0007 0.002
Loa Loa (eye worm) RGC/RGC protein kinase 0.0079 0.0049 0.0049
Mycobacterium ulcerans protoporphyrinogen oxidase 0.0381 0.0269 0.0685
Loa Loa (eye worm) hypothetical protein 0.0021 0.0007 0.0007
Echinococcus multilocularis glutamate receptor 2 0.0526 0.0374 0.1042
Loa Loa (eye worm) hypothetical protein 0.0167 0.0114 0.0114
Brugia malayi Dopamine receptor protein 1 0.0167 0.0114 0.0114
Echinococcus multilocularis tar DNA binding protein 0.0189 0.0129 0.036
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0339 0.0238 0.0663
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0073 0.0045 0.0045
Loa Loa (eye worm) metabotropic glutamate receptor 8 0.0077 0.0048 0.0048
Loa Loa (eye worm) hypothetical protein 0.0167 0.0114 0.0114
Echinococcus granulosus tm gpcr rhodopsin 0.0668 0.0477 0.1328
Onchocerca volvulus 0.0021 0.0007 0.0017
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0167 0.0114 0.0316
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0058 0.0034 0.0034
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0021 0.0007 0.0018
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0167 0.0114 0.0316
Treponema pallidum amino acid ABC transporter, periplasmic binding protein 0.0157 0.0106 0.4139
Schistosoma mansoni 60S ribosomal protein L21 0.0012 0.0001 0.0002
Echinococcus multilocularis 0.0381 0.0269 0.0747
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0015 0.0003 0.0008
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0029 0.0013 0.0179
Brugia malayi neuropeptide F receptor 0.0167 0.0114 0.0114
Echinococcus granulosus netrin receptor unc 5 0.0015 0.0003 0.0008
Brugia malayi G protein-coupled receptor F59B2.13 0.0167 0.0114 0.0114
Trypanosoma cruzi hypothetical protein, conserved 0.0151 0.0102 0.0102
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0483 0.0343 0.0954
Trichomonas vaginalis D-aminoacylase, putative 0.0151 0.0102 1
Brugia malayi Receptor family ligand binding region containing protein 0.0077 0.0048 0.0048
Echinococcus multilocularis vesicular acetylcholine transporter 0.4955 0.3593 1
Mycobacterium ulcerans hypothetical protein 0.0151 0.0102 0.026
Loa Loa (eye worm) hypothetical protein 0.0012 0.0001 0.0001
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0151 0.0102 0.0283
Brugia malayi Patched family protein 0.0012 0.0001 0.0001
Loa Loa (eye worm) peptidase family M1 containing protein 0.0021 0.0007 0.0007
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0053 0.0031 0.0031
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0015 0.0003 0.0008
Loa Loa (eye worm) isocitrate dehydrogenase 0.0016 0.0003 0.0003
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0053 0.0031 0.0031
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0029 0.0013 0.0013
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0058 0.0034 0.0877
Schistosoma mansoni neuropeptide receptor 0.0167 0.0114 0.0316
Giardia lamblia Kinase, CMGC MAPK 0.0053 0.0031 1
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0965 0.0693 0.1903
Brugia malayi Myosin head containing protein 0.0012 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0231 0.016 0.0159
Loa Loa (eye worm) hypothetical protein 0.0167 0.0114 0.0114
Entamoeba histolytica fatty acid elongase, putative 0.0124 0.0082 0.5839
Loa Loa (eye worm) hypothetical protein 0.0012 0.0001 0.0001
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0029 0.0013 0.0179
Loa Loa (eye worm) hypothetical protein 0.0015 0.0003 0.0003
Plasmodium vivax beta-ketoacyl-acyl carrier protein synthase III precursor, putative 0.0954 0.0685 1
Brugia malayi hypothetical protein 0.0012 0.0001 0.0001
Onchocerca volvulus 0.0339 0.0238 0.0662
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.0021 0.0007 0.0472
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0167 0.0114 0.0316
Echinococcus granulosus lysine specific histone demethylase 1A 0.0381 0.0269 0.0747
Echinococcus granulosus rhodopsin orphan GPCR 0.0167 0.0114 0.0316
Echinococcus multilocularis g protein coupled receptor 0.0167 0.0114 0.0316
Loa Loa (eye worm) hypothetical protein 0.0167 0.0114 0.0114
Trypanosoma cruzi cytochrome P450, putative 0.002 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0012 0.0001 0.0001
Chlamydia trachomatis arginine ABC transporter substrate-binding protein ArtJ 0.0157 0.0106 0.1387
Echinococcus granulosus beta LACTamase domain containing family member 0.0151 0.0102 0.0283
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0021 0.0007 0.0007
Trypanosoma cruzi UDP-galactopyranose mutase 0.0381 0.0269 0.0269
Loa Loa (eye worm) hypothetical protein 0.0058 0.0034 0.0034
Loa Loa (eye worm) TK/EGFR protein kinase 0.0292 0.0204 0.0204
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0167 0.0114 0.0316
Echinococcus granulosus neuropeptide s receptor 0.0167 0.0114 0.0316
Loa Loa (eye worm) hypothetical protein 0.0012 0.0001 0.0001
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0021 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0167 0.0114 0.0114
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0167 0.0114 0.0114
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0167 0.0114 0.0114
Loa Loa (eye worm) hypothetical protein 0.0077 0.0048 0.0048
Toxoplasma gondii patched family protein 0.0012 0.0001 0.0016
Plasmodium falciparum M1-family alanyl aminopeptidase, putative 0.0021 0.0007 0.01
Trichomonas vaginalis esterase, putative 0.0151 0.0102 1
Loa Loa (eye worm) hypothetical protein 0.1848 0.1335 0.1335
Loa Loa (eye worm) hypothetical protein 0.0021 0.0007 0.0007
Brugia malayi beta-lactamase family protein 0.0151 0.0102 0.0102
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0007 0.0007
Echinococcus granulosus sterol regulatory element binding protein 0.0085 0.0053 0.0149
Brugia malayi hypothetical protein 0.0011 0.0000040859 0.0000027371
Loa Loa (eye worm) hypothetical protein 0.0015 0.0003 0.0003
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.007 0.0043 0.4081
Loa Loa (eye worm) doublecortin family protein 0.0021 0.0007 0.0007
Brugia malayi hypothetical protein 0.0058 0.0034 0.0034
Echinococcus granulosus Ankyrin 0.0015 0.0003 0.0008
Echinococcus multilocularis RUN 0.0021 0.0007 0.0019
Echinococcus multilocularis rhodopsin orphan GPCR 0.0167 0.0114 0.0316
Loa Loa (eye worm) hypothetical protein 0.0197 0.0135 0.0135
Trypanosoma cruzi cytochrome P450, putative 0.002 0.0007 0.0007
Echinococcus multilocularis neuropeptide Y receptor 0.0167 0.0114 0.0316
Toxoplasma gondii aminopeptidase N protein 0.0541 0.0385 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0167 0.0114 0.0316
Loa Loa (eye worm) hypothetical protein 0.0012 0.0001 0.0001
Mycobacterium ulcerans 3-oxoacyl-ACP synthase 0.0954 0.0685 0.1749
Loa Loa (eye worm) carboxylesterase 0.0063 0.0038 0.0038
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0016 0.0003 0.0009
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0167 0.0114 0.0316
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0167 0.0114 0.0316
Brugia malayi Uncoordinated protein 44 0.0015 0.0003 0.0003
Onchocerca volvulus 0.0013 0.0001 0.0001
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0021 0.0007 0.0021
Echinococcus multilocularis protein dispatched 1 0.0097 0.0062 0.0173
Schistosoma mansoni loxhd1 0.0021 0.0007 0.0019
Loa Loa (eye worm) hypothetical protein 0.0016 0.0003 0.0003
Brugia malayi putative neuropeptide receptor 0.0167 0.0114 0.0114
Loa Loa (eye worm) hypothetical protein 0.0012 0.0001 0.0001
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0167 0.0114 0.0316
Schistosoma mansoni hypothetical protein 0.0507 0.0361 0.1004
Schistosoma mansoni opsin-like receptor 0.0167 0.0114 0.0316
Echinococcus multilocularis sodium and chloride dependent glycine 0.0058 0.0034 0.0094
Loa Loa (eye worm) hypothetical protein 0.0012 0.0001 0.0001
Mycobacterium tuberculosis Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) 0.5023 0.3643 1
Loa Loa (eye worm) hypothetical protein 0.0025 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0012 0.0001 0.0001
Brugia malayi Dopamine receptor 0.0167 0.0114 0.0114
Plasmodium vivax hypothetical protein, conserved 0.0151 0.0102 0.1476
Entamoeba histolytica fatty acid elongase, putative 0.0124 0.0082 0.5839
Leishmania major extracellular receptor, putative 0.0077 0.0048 0.0048
Loa Loa (eye worm) hypothetical protein 0.0021 0.0007 0.0007
Brugia malayi Receptor family ligand binding region containing protein 0.0079 0.0049 0.0049
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0167 0.0114 0.0316
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0029 0.0013 0.0036
Mycobacterium ulcerans lipase LipD 0.0151 0.0102 0.026
Echinococcus multilocularis p2X purinoceptor 4 0.0033 0.0016 0.0044
Schistosoma mansoni tyrosine kinase 0.0155 0.0105 0.0292
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0015 0.0003 0.0003
Trypanosoma cruzi metallo-peptidase, clan MA(E), family M1, putative 0.0021 0.0007 0.0007
Trichomonas vaginalis CMGC family protein kinase 0.0053 0.0031 0.2811
Loa Loa (eye worm) hypothetical protein 0.0381 0.0269 0.0269
Echinococcus granulosus neuropeptide receptor 0.0167 0.0114 0.0316
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0016 0.0003 0.0039
Onchocerca volvulus 0.0167 0.0114 0.0314
Echinococcus granulosus cpg binding protein 0.003 0.0014 0.0038
Loa Loa (eye worm) serotonin transporter b 0.0339 0.0238 0.0238
Echinococcus granulosus neuropeptides capa receptor 0.0167 0.0114 0.0316
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0058 0.0034 0.0034
Schistosoma mansoni histamine h1 receptor 0.0167 0.0114 0.0316
Loa Loa (eye worm) patched family protein 0.0012 0.0001 0.0001
Brugia malayi Nuclear hormone receptor-like 1 0.0011 0.0000040859 0.0000027371
Echinococcus multilocularis G protein coupled receptor 139 0.0167 0.0114 0.0316
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0021 0.0007 0.0007
Schistosoma mansoni steroid hormone receptor ad4bp 0.0021 0.0007 0.002
Echinococcus multilocularis somatostatin receptor 0.0167 0.0114 0.0316
Schistosoma mansoni Lysine-specific histone demethylase 1 0.0381 0.0269 0.0747
Schistosoma mansoni tyrosine kinase 0.0157 0.0106 0.0295
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0021 0.0007 0.0021
Echinococcus multilocularis neuropeptide FF receptor 2 0.0167 0.0114 0.0316
Schistosoma mansoni leukotriene A4 hydrolase (M01 family) 0.0021 0.0007 0.0021
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0021 0.0007 0.002
Loa Loa (eye worm) hypothetical protein 0.0167 0.0114 0.0114
Loa Loa (eye worm) hypothetical protein 0.0167 0.0114 0.0114
Brugia malayi latrophilin 2 splice variant baaae 0.0158 0.0106 0.0106
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0029 0.0013 0.0179
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.002 0.0007 0.0017
Echinococcus granulosus nuclear factor of activated T cells 5 0.0077 0.0048 0.0133
Schistosoma mansoni hypothetical protein 0.0021 0.0007 0.0019
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0058 0.0034 0.0094
Echinococcus multilocularis glutamate receptor ionotropic kainate 0.0325 0.0228 0.0636
Schistosoma mansoni tar DNA-binding protein 0.0189 0.0129 0.036
Plasmodium vivax thioredoxin reductase, putative 0.0083 0.0052 0.0755
Echinococcus multilocularis geminin 0.0507 0.0361 0.1004
Loa Loa (eye worm) hypothetical protein 0.0012 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0025 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0058 0.0034 0.0034
Mycobacterium tuberculosis Conserved protein 0.0151 0.0102 0.0279
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0015 0.0003 0.0008
Loa Loa (eye worm) hypothetical protein 0.0167 0.0114 0.0114
Echinococcus granulosus fatty acid amide hydrolase 1 0.0076 0.0047 0.0131
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0091 0.0058 0.0162
Brugia malayi Patched family protein 0.0012 0.0001 0.0001
Echinococcus granulosus dnaJ subfamily B 0.0405 0.0286 0.0797
Echinococcus granulosus p2X purinoceptor 4 0.0033 0.0016 0.0044
Trypanosoma brucei C-8 sterol isomerase, putative 1.3771 1 1
Schistosoma mansoni nuclear hormone receptor 0.0021 0.0007 0.002
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0167 0.0114 0.0316
Echinococcus multilocularis 0.0011 0.0000013488 0.0000035872
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0167 0.0114 0.0316
Schistosoma mansoni tyrosine kinase 0.0157 0.0106 0.0295
Brugia malayi GnHR receptor homolog 0.0167 0.0114 0.0114
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0015 0.0003 0.0008
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0029 0.0013 0.0035
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0007 0.002
Echinococcus granulosus sex peptide receptor 0.0167 0.0114 0.0316
Echinococcus granulosus thioredoxin glutathione reductase 0.0084 0.0053 0.0147
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0167 0.0114 0.0316
Schistosoma mansoni biogenic amine (5HT) receptor 0.0167 0.0114 0.0316
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0015 0.0003 0.0003
Brugia malayi hypothetical protein 0.0021 0.0007 0.0007
Schistosoma mansoni hypothetical protein 0.0011 0.0000013488 0.0000037538
Echinococcus granulosus neuropeptides capa receptor 0.0167 0.0114 0.0316
Brugia malayi Patched family protein 0.0012 0.0001 0.0001
Echinococcus granulosus ecdysone induced protein 78C 0.0021 0.0007 0.002
Echinococcus multilocularis insulin receptor 0.0093 0.006 0.0166
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.5404 0.3919 1
Mycobacterium leprae conserved hypothetical protein 0.0151 0.0102 0.3788
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0167 0.0114 0.0114
Loa Loa (eye worm) hypothetical protein 0.0167 0.0114 0.0114
Schistosoma mansoni opsin-like receptor 0.0167 0.0114 0.0316
Loa Loa (eye worm) hypothetical protein 0.0167 0.0114 0.0114
Echinococcus multilocularis g-protein coupled receptor 0.0167 0.0114 0.0316
Echinococcus multilocularis rhodopsin orphan GPCR 0.0167 0.0114 0.0316
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0093 0.006 0.0166
Echinococcus granulosus g-protein coupled receptor 0.0167 0.0114 0.0316
Schistosoma mansoni hypothetical protein 0.0082 0.0051 0.0142
Loa Loa (eye worm) hypothetical protein 0.0012 0.0001 0.0001
Echinococcus granulosus lysine specific histone demethylase 1A 0.0381 0.0269 0.0747
Onchocerca volvulus 0.0058 0.0034 0.0092
Echinococcus granulosus epidermal growth factor receptor 0.0157 0.0106 0.0295
Schistosoma mansoni hypothetical protein 0.0073 0.0045 0.0125
Brugia malayi Serotonin receptor 0.1801 0.1301 0.1301
Schistosoma mansoni alpha-1 adrenergic receptor 0.0167 0.0114 0.0316
Brugia malayi protein C24B5.3 0.0012 0.0001 0.0001
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.0021 0.0007 0.0472
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0053 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0012 0.0001 0.0001
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0058 0.0034 0.0094
Schistosoma mansoni hypothetical protein 0.0167 0.0114 0.0316
Brugia malayi Peptidase family M1 containing protein 0.0021 0.0007 0.0007
Trichomonas vaginalis glutathione reductase, putative 0.0029 0.0013 0.102
Schistosoma mansoni neuropeptide F-like receptor 0.0167 0.0114 0.0316
Schistosoma mansoni coup transcription factor 0.0021 0.0007 0.002
Loa Loa (eye worm) hypothetical protein 0.0021 0.0007 0.0007
Schistosoma mansoni glutamate receptor NMDA 0.1547 0.1116 0.3107
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0852 0.0611 0.17
Loa Loa (eye worm) hypothetical protein 0.0167 0.0114 0.0114
Loa Loa (eye worm) hypothetical protein 0.0077 0.0048 0.0048
Loa Loa (eye worm) RNA binding protein 0.0189 0.0129 0.0129
Brugia malayi cytoplasmic intermediate filament protein 0.0014 0.0002 0.0002
Brugia malayi Carboxylesterase family protein 0.0063 0.0038 0.0038
Schistosoma mansoni RAR-like nuclear receptor 0.0021 0.0007 0.002
Echinococcus granulosus somatostatin receptor 0.0167 0.0114 0.0316
Brugia malayi Patched family protein 0.0012 0.0001 0.0001
Plasmodium falciparum protoporphyrinogen oxidase 0.0381 0.0269 0.3912
Toxoplasma gondii hypothetical protein 0.0058 0.0034 0.0877
Brugia malayi Calcitonin receptor-like protein seb-1 0.0231 0.016 0.0159
Schistosoma mansoni neuropeptide f receptor 76f 0.0167 0.0114 0.0316
Loa Loa (eye worm) beta-lactamase 0.0151 0.0102 0.0102
Loa Loa (eye worm) hypothetical protein 0.0167 0.0114 0.0114
Echinococcus granulosus g protein coupled receptor 0.0167 0.0114 0.0316
Loa Loa (eye worm) hypothetical protein 0.0011 0.0000040859 0.0000027371
Schistosoma mansoni hypothetical protein 0.0167 0.0114 0.0316
Echinococcus granulosus neuropeptide FF receptor 2 0.0167 0.0114 0.0316
Schistosoma mansoni hypothetical protein 0.0011 0.000000059849 0.00000016656
Loa Loa (eye worm) hypothetical protein 0.0012 0.0001 0.0001
Brugia malayi Patched family protein 0.0012 0.0001 0.0001
Brugia malayi hypothetical protein 0.0077 0.0048 0.0048
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0025 0.001 0.001
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0029 0.0013 0.0033
Schistosoma mansoni ankyrin 23/unc44 0.0015 0.0003 0.0008
Echinococcus multilocularis lamin 0.0025 0.001 0.0029
Echinococcus multilocularis epidermal growth factor receptor 0.0292 0.0204 0.0568
Loa Loa (eye worm) cytochrome P450 family protein 0.002 0.0007 0.0007
Treponema pallidum amino acid ABC transporter, periplasmic binding protein (hisJ) 0.0157 0.0106 0.4139
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0021 0.0007 0.002
Brugia malayi Patched family protein 0.0012 0.0001 0.0001
Echinococcus granulosus rhodopsin orphan GPCR 0.0167 0.0114 0.0316
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0015 0.0003 0.0003
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.019 0.013 0.0356
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0151 0.0102 0.026
Onchocerca volvulus 0.0016 0.0003 0.0007
Echinococcus multilocularis serotonin receptor 0.1848 0.1335 0.3715
Toxoplasma gondii patched family protein 0.0012 0.0001 0.0016
Loa Loa (eye worm) hypothetical protein 0.0012 0.0001 0.0001
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.001 0.0135
Schistosoma mansoni P2X receptor subunit 0.0033 0.0016 0.0044
Echinococcus multilocularis aminopeptidase N 0.0021 0.0007 0.0021
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0013 0.0001 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.0085 0.0053 0.5116
Brugia malayi Peptidase family M1 containing protein 0.0021 0.0007 0.0007
Brugia malayi nuclear receptor NHR-88 0.0021 0.0007 0.0007
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0063 0.0038 0.0106
Schistosoma mansoni metabotropic glutamate receptor 0.0077 0.0048 0.0133
Loa Loa (eye worm) hypothetical protein 0.0021 0.0007 0.0007
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0058 0.0034 0.0094
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0015 0.0003 0.0008
Brugia malayi hypothetical protein 0.0025 0.001 0.001
Schistosoma mansoni polycystin 1-related 0.0021 0.0007 0.0019
Echinococcus granulosus carboxylesterase 5A 0.0063 0.0038 0.0106
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0021 0.0007 0.002
Echinococcus granulosus biogenic amine 5HT receptor 0.1848 0.1335 0.3715
Brugia malayi neuropeptide F receptor 0.0167 0.0114 0.0114
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0167 0.0114 0.0114
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0167 0.0114 0.0114
Echinococcus granulosus glutamate NMDA receptor subunit 0.1547 0.1116 0.3107
Schistosoma mansoni tyrosine kinase 0.0155 0.0105 0.0292
Onchocerca volvulus 0.0151 0.0102 0.0281
Brugia malayi Patched family protein 0.0012 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0167 0.0114 0.0114
Echinococcus multilocularis Niemann Pick C1 protein 0.0197 0.0135 0.0376
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0167 0.0114 0.0114
Brugia malayi Patched protein homolog 1 0.0012 0.0001 0.0001
Echinococcus multilocularis leukotriene A 4 hydrolase 0.0021 0.0007 0.0021
Schistosoma mansoni hypothetical protein 0.0082 0.0051 0.0142
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0003 0.0003
Mycobacterium tuberculosis Conserved protein 0.0151 0.0102 0.0279
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0852 0.0611 0.17
Plasmodium vivax M1-family alanyl aminopeptidase, putative 0.0541 0.0385 0.5613
Echinococcus multilocularis protoporphyrinogen oxidase 0.0381 0.0269 0.0747
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0058 0.0034 0.0094
Loa Loa (eye worm) hypothetical protein 0.0167 0.0114 0.0114
Onchocerca volvulus 0.0167 0.0114 0.0314
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0167 0.0114 0.0316
Brugia malayi hypothetical protein 0.0381 0.0269 0.0269
Brugia malayi Protein kinase domain containing protein 0.0043 0.0023 0.0023
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0058 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0167 0.0114 0.0114
Schistosoma mansoni tyrosine kinase 0.0155 0.0105 0.0292
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0151 0.0102 0.0102
Mycobacterium tuberculosis Probable lipase LipE 0.0151 0.0102 0.0279
Echinococcus multilocularis isocitrate dehydrogenase 0.0016 0.0003 0.0009
Schistosoma mansoni hypothetical protein 0.0082 0.0051 0.0142
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0167 0.0114 0.0316
Onchocerca volvulus 0.0167 0.0114 0.0314
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0167 0.0114 0.0316
Trichomonas vaginalis penicillin-binding protein, putative 0.0151 0.0102 1
Loa Loa (eye worm) hypothetical protein 0.0011 0.0000040859 0.0000027371
Echinococcus granulosus glutamate receptor ionotropic kainate 3 0.0325 0.0228 0.0636
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0029 0.0013 0.0013
Brugia malayi hypothetical protein 0.0167 0.0114 0.0114
Loa Loa (eye worm) hypothetical protein 0.0012 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0167 0.0114 0.0114
Brugia malayi hypothetical protein 0.0167 0.0114 0.0114
Loa Loa (eye worm) hypothetical protein 0.0339 0.0238 0.0238
Loa Loa (eye worm) TATA binding protein associated factor 0.0021 0.0007 0.0007
Echinococcus multilocularis GPCR, family 2 0.0073 0.0045 0.0125
Schistosoma mansoni thyroid hormone receptor 0.0021 0.0007 0.002
Schistosoma mansoni Tata binding protein associated factor (M01 family) 0.0021 0.0007 0.0021
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0022 0.0008 0.0022
Onchocerca volvulus 0.0013 0.0001 0.0001
Echinococcus multilocularis glutamate receptor 2 0.0852 0.0611 0.17
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0003 0.0003
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0852 0.0611 0.17
Leishmania major hypothetical protein, conserved 0.0041 0.0022 0.0022
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0167 0.0114 0.0316
Plasmodium falciparum thioredoxin reductase 0.0083 0.0052 0.0755
Brugia malayi nuclear hormone receptor 0.0021 0.0007 0.0007
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0167 0.0114 0.0316
Schistosoma mansoni tar DNA-binding protein 0.0189 0.0129 0.036
Echinococcus granulosus biogenic amine 5HT receptor 0.0167 0.0114 0.0316
Brugia malayi Serotonin receptor 0.0167 0.0114 0.0114
Loa Loa (eye worm) hypothetical protein 0.0021 0.0007 0.0007
Schistosoma mansoni aminopeptidase A (M01 family) 0.0021 0.0007 0.0021
Brugia malayi Melatonin receptor type 1A 0.0167 0.0114 0.0114
Leishmania major C-8 sterol isomerase-like protein 1.3771 1 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0167 0.0114 0.0316
Loa Loa (eye worm) hypothetical protein 0.0011 0.0000040859 0.0000027371
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0852 0.0611 0.17
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0093 0.006 0.0166
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0151 0.0102 0.0279
Echinococcus multilocularis tyrosine kinase 0.0079 0.0049 0.0136
Schistosoma mansoni serine/threonine protein kinase 0.0053 0.0031 0.0085
Toxoplasma gondii histone lysine methyltransferase SET1 0.0054 0.0031 0.0808
Loa Loa (eye worm) norepinephrine transporter 0.0339 0.0238 0.0238
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0091 0.0058 0.0162
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0167 0.0114 0.0316
Echinococcus granulosus hypothetical protein 0.0836 0.06 0.1669
Loa Loa (eye worm) hypothetical protein 0.0063 0.0038 0.0038
Brugia malayi Carboxylesterase family protein 0.0063 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.0167 0.0114 0.0114
Loa Loa (eye worm) hypothetical protein 0.0167 0.0114 0.0114
Brugia malayi SEA domain containing protein 0.0013 0.0001 0.0001
Mycobacterium leprae Probable lipase LipE 0.0151 0.0102 0.3788
Loa Loa (eye worm) hypothetical protein 0.0151 0.0102 0.0102
Toxoplasma gondii patched family protein 0.0012 0.0001 0.0016
Echinococcus multilocularis hyperpolarization activated cyclic 0.0015 0.0003 0.0008
Brugia malayi intermediate filament protein 0.0025 0.001 0.001
Echinococcus multilocularis thyroid hormone receptor alpha 0.0021 0.0007 0.002
Toxoplasma gondii histone lysine-specific demethylase 0.0381 0.0269 0.6974
Schistosoma mansoni patched 1 0.0085 0.0053 0.0149
Brugia malayi G-protein coupled receptor 0.0167 0.0114 0.0114
Mycobacterium tuberculosis Probable esterase LipL 0.0151 0.0102 0.0279
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0022 0.0008 0.0008
Echinococcus multilocularis Niemann Pick C1 protein 0.0282 0.0197 0.0547
Brugia malayi Protein kinase domain containing protein 0.0015 0.0003 0.0003
Schistosoma mansoni voltage-gated potassium channel 0.0082 0.0052 0.0144
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.001 0.0135
Echinococcus multilocularis mitogen activated protein kinase 0.0053 0.0031 0.0085
Onchocerca volvulus Vesicular acetylcholine transporter homolog 0.4955 0.3593 1
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0231 0.016 0.0159
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.003 0.0014 0.0038
Schistosoma mansoni glutamate receptor AMPA 0.0775 0.0555 0.1545
Trypanosoma brucei aminopeptidase, putative 0.0021 0.0007 0.0007
Echinococcus granulosus metabotropic glutamate receptor 5 0.0077 0.0048 0.0133
Brugia malayi RE15519p 0.0167 0.0114 0.0114
Loa Loa (eye worm) hypothetical protein 0.0012 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0167 0.0114 0.0114
Echinococcus multilocularis lamin dm0 0.0025 0.001 0.0029
Onchocerca volvulus 0.0021 0.0007 0.0017
Loa Loa (eye worm) hypothetical protein 0.0012 0.0001 0.0001
Plasmodium falciparum LCCL domain-containing protein 0.0021 0.0007 0.0092
Plasmodium falciparum cysteine repeat modular protein 1 0.0041 0.0022 0.0313
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0079 0.0049 0.0135
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0015 0.0003 0.0008
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0058 0.0034 0.0094
Brugia malayi Steroid receptor seven-up type 2 0.0021 0.0007 0.0007
Onchocerca volvulus 0.0167 0.0114 0.0314
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0029 0.0013 0.0013
Echinococcus multilocularis rhodopsin orphan GPCR 0.0167 0.0114 0.0316
Loa Loa (eye worm) hypothetical protein 0.0151 0.0102 0.0102
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0058 0.0034 0.0877
Schistosoma mansoni lipoxygenase 0.0086 0.0055 0.0152
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0021 0.0007 0.0021
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0167 0.0114 0.0316
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0016 0.0003 0.0039
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0151 0.0102 0.0279
Echinococcus granulosus geminin 0.0507 0.0361 0.1004
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0123 0.0081 0.0227
Toxoplasma gondii patched family protein 0.0012 0.0001 0.0016
Plasmodium vivax multidomain scavenger receptor, putative 0.0021 0.0007 0.0092
Schistosoma mansoni biogenic amine receptor 0.0167 0.0114 0.0316
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0167 0.0114 0.0314
Echinococcus multilocularis rhodopsin orphan GPCR 0.0167 0.0114 0.0316
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0021 0.0007 0.0021
Echinococcus granulosus aminopeptidase N 0.0021 0.0007 0.0021
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0012 0.0001 0.0002
Trichomonas vaginalis D-aminoacylase, putative 0.0151 0.0102 1
Schistosoma mansoni tar DNA-binding protein 0.0189 0.0129 0.036
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0058 0.0034 0.0877
Mycobacterium ulcerans dehydrogenase 0.0381 0.0269 0.0685
Trypanosoma cruzi trypanothione reductase, putative 0.0029 0.0013 0.0013
Trypanosoma cruzi aminopeptidase, putative 0.0021 0.0007 0.0007
Echinococcus granulosus cytochrome P450 2K1 0.0011 0.0000013488 0.0000035872
Onchocerca volvulus 0.0381 0.0269 0.0746
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0091 0.0058 0.0058
Schistosoma mansoni growth hormone secretagogue receptor 0.0167 0.0114 0.0316
Brugia malayi Intermediate filament tail domain containing protein 0.0025 0.001 0.001
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0029 0.0013 0.0013
Echinococcus multilocularis Ankyrin 0.0015 0.0003 0.0008
Echinococcus granulosus lamin dm0 0.0025 0.001 0.0029
Brugia malayi G protein-coupled receptor 0.0167 0.0114 0.0114
Brugia malayi beta-lactamase family protein 0.0151 0.0102 0.0102
Brugia malayi hypothetical protein 0.0012 0.0001 0.0001
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0007 0.0007
Plasmodium falciparum amino acid transporter, putative 0.0058 0.0034 0.0484
Plasmodium falciparum glutathione reductase 0.0083 0.0052 0.0755
Brugia malayi amidase 0.0076 0.0047 0.0047
Loa Loa (eye worm) hypothetical protein 0.0167 0.0114 0.0114
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0021 0.0007 0.0021
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 0.0021 0.0007 0.0007
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0339 0.0238 0.0238
Loa Loa (eye worm) TYRA-2 protein 0.0167 0.0114 0.0114
Brugia malayi ecdysteroid receptor 0.0021 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0167 0.0114 0.0114
Onchocerca volvulus 0.0058 0.0034 0.0092
Loa Loa (eye worm) hypothetical protein 0.0073 0.0045 0.0045
Echinococcus granulosus atrial natriuretic peptide receptor 0.0077 0.0048 0.0133
Brugia malayi hypothetical protein 0.0167 0.0114 0.0114
Loa Loa (eye worm) hypothetical protein 0.0011 0.0000040859 0.0000027371
Leishmania major trypanothione reductase 0.0083 0.0052 0.0052
Brugia malayi TAR-binding protein 0.0189 0.0129 0.0129
Schistosoma mansoni neuropeptide receptor 0.0167 0.0114 0.0316
Trypanosoma cruzi UDP-galactopyranose mutase 0.0381 0.0269 0.0269
Loa Loa (eye worm) hypothetical protein 0.0058 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0077 0.0048 0.0048
Echinococcus multilocularis atrial natriuretic peptide receptor 0.0077 0.0048 0.0133
Plasmodium falciparum transporter, putative 0.0058 0.0034 0.0484
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0029 0.0013 0.0013
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.007 0.0043 0.4081
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.001 0.001
Loa Loa (eye worm) latrophilin receptor protein 2 0.0073 0.0045 0.0045
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0058 0.0034 0.0034
Loa Loa (eye worm) neuropeptide F receptor 0.0167 0.0114 0.0114
Schistosoma mansoni biogenic amine receptor 0.0167 0.0114 0.0316
Schistosoma mansoni cpg binding protein 0.003 0.0014 0.0038
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0058 0.0034 0.0094
Brugia malayi AKH receptor 0.0167 0.0114 0.0114
Schistosoma mansoni hypothetical protein 0.0013 0.0001 0.0003
Onchocerca volvulus Netrin receptor homolog 0.0015 0.0003 0.0006
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0167 0.0114 0.0316
Loa Loa (eye worm) hypothetical protein 0.0058 0.0034 0.0034
Echinococcus granulosus FTZ F1 alpha 0.0021 0.0007 0.002
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0007 0.0007
Loa Loa (eye worm) glutamate receptor 1 0.0775 0.0555 0.0555
Echinococcus granulosus tachykinin peptides receptor 99D 0.0167 0.0114 0.0316
Schistosoma mansoni sodium/chloride dependent transporter 0.0058 0.0034 0.0094
Echinococcus multilocularis glutamate receptor 2 0.0775 0.0555 0.1545
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0058 0.0034 0.0094
Echinococcus granulosus g protein coupled receptor 0.0167 0.0114 0.0316
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0151 0.0102 0.0283
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0167 0.0114 0.0114
Echinococcus granulosus voltage gated potassium channel 0.0022 0.0008 0.0022
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0021 0.0007 0.0007
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0167 0.0114 0.0114
Onchocerca volvulus 0.0079 0.0049 0.0135
Echinococcus granulosus dro:myosuppressin receptor 0.0167 0.0114 0.0316
Loa Loa (eye worm) hypothetical protein 0.0077 0.0048 0.0048
Trypanosoma brucei Aminopeptidase M1, putative 0.0021 0.0007 0.0007
Schistosoma mansoni tyrosine kinase 0.0079 0.0049 0.0136
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0852 0.0611 0.17
Brugia malayi Patched family protein 0.0012 0.0001 0.0001
Schistosoma mansoni adenoreceptor 0.0167 0.0114 0.0316
Loa Loa (eye worm) glutathione reductase 0.0083 0.0052 0.0052
Leishmania major cytochrome p450-like protein 0.002 0.0007 0.0007
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0021 0.0007 0.002
Schistosoma mansoni glutamate receptor NMDA 0.1086 0.0781 0.2174

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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