Detailed information for compound 899494

Basic information

Technical information
  • TDR Targets ID: 899494
  • Name: N-[1-(4-chlorophenyl)-2,4,6-trioxo-5-(trifluo romethyl)-7H-pyrrolo[4,5-e]pyrimidin-5-yl]-4- methoxybenzamide
  • MW: 494.808 | Formula: C21H14ClF3N4O5
  • H donors: 3 H acceptors: 4 LogP: 2.48 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1ccc(cc1)C(=O)NC1(C(=O)Nc2c1c(=O)[nH]c(=O)n2c1ccc(cc1)Cl)C(F)(F)F
  • InChi: 1S/C21H14ClF3N4O5/c1-34-13-8-2-10(3-9-13)16(30)28-20(21(23,24)25)14-15(26-18(20)32)29(19(33)27-17(14)31)12-6-4-11(22)5-7-12/h2-9H,1H3,(H,26,32)(H,28,30)(H,27,31,33)
  • InChiKey: BHNFOTHVERHHOF-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N-[1-(4-chlorophenyl)-2,4,6-trioxo-5-(trifluoromethyl)-7H-pyrrolo[4,5-e]pyrimidin-5-yl]-4-methoxy-benzamide
  • N-[1-(4-chlorophenyl)-2,4,6-triketo-5-(trifluoromethyl)-7H-pyrrolo[4,5-e]pyrimidin-5-yl]-4-methoxy-benzamide
  • A2927/0123180

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0026 0.0056 0.0048
Echinococcus multilocularis smad 0.0047 0.0133 0.0133
Entamoeba histolytica cysteine protease, putative 0.0085 0.0273 0.0253
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0085 0.0273 0.0253
Brugia malayi mothers against decapentaplegic homolog 3 0.0021 0.0036 0.0036
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0091 0.0298 0.0298
Loa Loa (eye worm) isocitrate dehydrogenase 0.0034 0.0084 0.0084
Trypanosoma brucei heat shock protein, putative 0.0017 0.002 0.0005
Entamoeba histolytica cysteine proteinase, putative 0.0327 0.1176 0.1158
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0029 0.0066 0.0059
Loa Loa (eye worm) hypothetical protein 0.003 0.0069 0.0069
Giardia lamblia Cysteine protease 0.0085 0.0273 0.0266
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0062 0.0189 0.0189
Schistosoma mansoni zinc finger protein 0.005 0.0145 0.0145
Brugia malayi MH1 domain containing protein 0.0026 0.0055 0.0055
Toxoplasma gondii aldehyde dehydrogenase 0.0029 0.0067 0.0413
Echinococcus granulosus polycomb protein SCMH1 0.0025 0.005 0.005
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0032 0.0077 0.0056
Schistosoma mansoni hypothetical protein 0.004 0.0107 0.0107
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0012 0.0004 0.0004
Schistosoma mansoni zinc finger protein 0.0034 0.0084 0.0084
Loa Loa (eye worm) hypothetical protein 0.005 0.0145 0.0145
Entamoeba histolytica hypothetical protein 0.0025 0.0052 0.0032
Loa Loa (eye worm) MH1 domain-containing protein 0.0021 0.0036 0.0036
Trypanosoma brucei heat shock protein 90, putative 0.0017 0.002 0.0005
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0106 0.0353 0.0353
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0085 0.0273 0.2256
Entamoeba histolytica cysteine proteinase 2 0.0183 0.0639 0.062
Echinococcus multilocularis GPCR, family 2 0.0172 0.0599 0.0599
Entamoeba histolytica cysteine protease, putative 0.0183 0.0639 0.062
Brugia malayi RNA, U transporter 1 0.0102 0.0338 0.0338
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0106 0.0353 0.0353
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0085 0.0273 0.2256
Entamoeba histolytica cysteine protease, putative 0.0183 0.0639 0.062
Onchocerca volvulus 0.0327 0.1176 0.1176
Brugia malayi cathepsin F-like cysteine proteinase 0.0098 0.0324 0.0324
Brugia malayi mbt repeat family protein 0.0025 0.005 0.005
Echinococcus granulosus cathepsin l1 0.0327 0.1176 0.1176
Onchocerca volvulus 0.0025 0.005 0.005
Giardia lamblia Cathepsin L precursor 0.0085 0.0273 0.0266
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0032 0.0077 0.0077
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0327 0.1176 0.1169
Leishmania major cathepsin L-like protease 0.0327 0.1176 0.1169
Schistosoma mansoni ap endonuclease 0.0019 0.0028 0.0028
Schistosoma mansoni hypothetical protein 0.0037 0.0095 0.0095
Plasmodium falciparum serine repeat antigen 3 0.0085 0.0273 0.2256
Plasmodium falciparum cysteine proteinase falcipain 3 0.0327 0.1176 1
Echinococcus granulosus endoplasmin 0.0013 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0043 0.0118 0.0118
Brugia malayi fibroinase precursor 0.0085 0.0273 0.0273
Brugia malayi ImpB/MucB/SamB family protein 0.0033 0.0082 0.0082
Brugia malayi Fli-1 protein 0.0106 0.0354 0.0354
Schistosoma mansoni chromobox protein 0.0034 0.0083 0.0083
Trypanosoma brucei DNA polymerase eta, putative 0.0033 0.0082 0.0066
Schistosoma mansoni endoplasmin 0.0017 0.002 0.002
Echinococcus multilocularis snurportin 1 0.0383 0.1385 0.1385
Brugia malayi Papain family cysteine protease containing protein 0.0183 0.0639 0.0639
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.054 0.1969 0.1952
Echinococcus granulosus lysine specific demethylase 5A 0.0091 0.0298 0.0298
Trypanosoma cruzi major cysteine proteinase, putative 0.0412 0.1493 0.1487
Schistosoma mansoni apoptosis regulator bax 0.0083 0.0266 0.0266
Echinococcus granulosus cathepsin b 0.1049 0.3865 0.3865
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0032 0.0077 0.0069
Brugia malayi nuclear receptor NHR-88 0.0106 0.0353 0.0353
Schistosoma mansoni thyroid hormone receptor 0.0106 0.0353 0.0353
Entamoeba histolytica Flap nuclease, putative 0.0026 0.0056 0.0035
Schistosoma mansoni tar DNA-binding protein 0.0101 0.0336 0.0336
Trypanosoma brucei DNA polymerase kappa, putative 0.0033 0.0082 0.0066
Onchocerca volvulus Alhambra homolog 0.0014 0.001 0.001
Brugia malayi Cathepsin L-like precursor 0.0327 0.1176 0.1176
Echinococcus multilocularis cysteine protease 0.0327 0.1176 0.1176
Trypanosoma brucei protein kinase, putative 0.0019 0.0029 0.0013
Onchocerca volvulus 0.0229 0.081 0.081
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0056 0.0167 0.0167
Toxoplasma gondii exonuclease III APE 0.0019 0.0028 0.0128
Schistosoma mansoni aldehyde dehydrogenase 0.0029 0.0067 0.0067
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0033 0.0082 0.0795
Loa Loa (eye worm) hypothetical protein 0.005 0.0145 0.0145
Brugia malayi nuclear receptor NHR-88 0.005 0.0145 0.0145
Loa Loa (eye worm) jmjC domain-containing protein 0.0023 0.0045 0.0045
Schistosoma mansoni niemann-pick C1 (NPC1) 0.009 0.0294 0.0294
Echinococcus multilocularis heat shock protein 0.0017 0.002 0.002
Schistosoma mansoni hypothetical protein 0.0172 0.0599 0.0599
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0012 0.0002 0.0002
Echinococcus multilocularis phd:f box containing protein 0.0023 0.0045 0.0045
Schistosoma mansoni hypothetical protein 0.0014 0.001 0.001
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0043 0.0028
Trypanosoma brucei DNA polymerase kappa, putative 0.0033 0.0082 0.0066
Loa Loa (eye worm) hypothetical protein 0.0106 0.0353 0.0353
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0512 0.1864 0.1864
Trypanosoma cruzi polo-like protein kinase, putative 0.2695 1 1
Schistosoma mansoni DNA polymerase eta 0.0033 0.0082 0.0082
Leishmania major DNA polymerase kappa, putative 0.0033 0.0082 0.0074
Echinococcus multilocularis lamin 0.0035 0.009 0.009
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0034 0.0084 0.0084
Echinococcus granulosus dna polymerase eta 0.0033 0.0082 0.0082
Echinococcus granulosus Protein patched homolog 1 0.0038 0.01 0.01
Echinococcus multilocularis tar DNA binding protein 0.0101 0.0336 0.0336
Echinococcus granulosus cathepsin L cysteine proteinase 0.0327 0.1176 0.1176
Loa Loa (eye worm) hypothetical protein 0.005 0.0145 0.0145
Giardia lamblia Cathepsin B precursor 0.0383 0.1384 0.1378
Brugia malayi hypothetical protein 0.1042 0.384 0.384
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0085 0.0273 0.0273
Giardia lamblia Encystation-specific protease 0.0085 0.0273 0.0266
Schistosoma mansoni jumonji domain containing protein 0.0108 0.0359 0.0359
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.054 0.1969 0.1962
Echinococcus multilocularis GA binding protein alpha chain 0.0035 0.0088 0.0088
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0085 0.0273 0.2256
Echinococcus multilocularis musashi 0.0035 0.009 0.009
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0327 0.1176 0.1176
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0079 0.0251 0.0251
Trypanosoma brucei RNA helicase, putative 0.0072 0.0227 0.0211
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0039 0.0103 0.0103
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0327 0.1176 0.1169
Echinococcus multilocularis polycomb protein SCMH1 0.0025 0.005 0.005
Loa Loa (eye worm) hypothetical protein 0.005 0.0145 0.0145
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0085 0.0273 0.2256
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0085 0.0273 0.0273
Echinococcus multilocularis expressed conserved protein 0.0083 0.0269 0.0269
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0106 0.0353 0.0353
Schistosoma mansoni hypothetical protein 0.0083 0.0266 0.0266
Schistosoma mansoni hypothetical protein 0.0153 0.053 0.053
Onchocerca volvulus 0.005 0.0145 0.0145
Brugia malayi hypothetical protein 0.0031 0.0074 0.0074
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0085 0.0273 0.2256
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0085 0.0273 0.0273
Loa Loa (eye worm) jmjC domain-containing protein 0.0091 0.0298 0.0298
Brugia malayi cathepsin Z-like cysteine proteinase 0.0085 0.0273 0.0273
Plasmodium falciparum ataxin-2 like protein, putative 0.0031 0.0074 0.0546
Trypanosoma cruzi cysteine peptidase, putative 0.0098 0.0324 0.0316
Loa Loa (eye worm) hypothetical protein 0.0035 0.009 0.009
Brugia malayi steroid hormone receptor 0.0106 0.0353 0.0353
Trypanosoma brucei heat shock protein, putative 0.0017 0.002 0.0005
Schistosoma mansoni gabp alpha 0.0035 0.0088 0.0088
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0106 0.0353 0.0353
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.054 0.1969 0.1962
Loa Loa (eye worm) hypothetical protein 0.0085 0.0273 0.0273
Schistosoma mansoni alpha-glucosidase 0.0068 0.021 0.021
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0085 0.0273 0.0266
Echinococcus multilocularis cathepsin L cysteine protease 0.0327 0.1176 0.1176
Brugia malayi Glycosyl hydrolases family 31 protein 0.0079 0.0251 0.0251
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.005 0.0145 0.0145
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0023 0.0045 0.0255
Trichomonas vaginalis conserved hypothetical protein 0.0085 0.0273 0.0266
Onchocerca volvulus Serine\/threonine kinase homolog 0.2695 1 1
Trichomonas vaginalis glutaminase, putative 0.0199 0.0699 0.0692
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0327 0.1176 0.1169
Schistosoma mansoni nuclear hormone receptor 0.0106 0.0353 0.0353
Echinococcus multilocularis Nuclear hormone receptor HR96 0.005 0.0145 0.0145
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0029 0.0067 0.0638
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0033 0.0082 0.0082
Brugia malayi MH1 domain containing protein 0.0026 0.0055 0.0055
Loa Loa (eye worm) intermediate filament protein 0.0035 0.009 0.009
Brugia malayi Papain family cysteine protease containing protein 0.0085 0.0273 0.0273
Giardia lamblia Cysteine protease 0.0085 0.0273 0.0266
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0106 0.0353 0.0353
Schistosoma mansoni aldehyde dehydrogenase 0.0029 0.0067 0.0067
Trypanosoma brucei DNA polymerase IV, putative 0.0033 0.0082 0.0066
Loa Loa (eye worm) hypothetical protein 0.005 0.0145 0.0145
Echinococcus granulosus survival motor neuron protein 1 0.0196 0.0687 0.0687
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0106 0.0353 0.0353
Loa Loa (eye worm) hypothetical protein 0.0229 0.081 0.081
Loa Loa (eye worm) endoplasmin 0.0017 0.002 0.002
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0103 0.0341 0.0341
Giardia lamblia Kinase, PLK 0.2695 1 1
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.005 0.0145 0.0145
Schistosoma mansoni transcription factor btf3 0.0025 0.0052 0.0052
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0327 0.1176 0.1169
Plasmodium vivax SET domain protein, putative 0.0062 0.0189 0.1532
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0028 0.002
Schistosoma mansoni heat shock protein 0.0017 0.002 0.002
Brugia malayi PHD-finger family protein 0.0043 0.0118 0.0118
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0654 0.2396 0.2384
Trypanosoma brucei heat shock protein, putative 0.0017 0.002 0.0005
Schistosoma mansoni cathepsin S (C01 family) 0.0085 0.0273 0.0273
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0062 0.0189 0.0189
Leishmania major cathepsin L-like protease 0.0654 0.2396 0.239
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.018 0.063 0.063
Schistosoma mansoni thyroid hormone receptor 0.0106 0.0353 0.0353
Schistosoma mansoni tar DNA-binding protein 0.0101 0.0336 0.0336
Trichomonas vaginalis conserved hypothetical protein 0.0085 0.0273 0.0266
Schistosoma mansoni kinase 0.137 0.5062 0.5062
Brugia malayi nuclear receptor RXR 0.005 0.0145 0.0145
Schistosoma mansoni jumonji/arid domain-containing protein 0.0091 0.0298 0.0298
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0085 0.0273 0.0273
Loa Loa (eye worm) hypothetical protein 0.0056 0.0167 0.0167
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0028 0.0028
Trypanosoma cruzi ISWI complex protein 0.0026 0.0056 0.0048
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0327 0.1176 0.1169
Plasmodium falciparum serine repeat antigen 4 0.0085 0.0273 0.2256
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0026 0.0056 0.0049
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0085 0.0273 0.0266
Entamoeba histolytica cysteine protease, putative 0.0183 0.0639 0.062
Echinococcus granulosus methyl CpG binding domain protein 2 0.0029 0.0067 0.0067
Echinococcus granulosus protein tyrosine kinase 0.0173 0.0601 0.0601
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0085 0.0273 0.0266
Echinococcus granulosus ecdysone induced protein 78C 0.0106 0.0353 0.0353
Echinococcus multilocularis mothers against decapentaplegic 2 0.0021 0.0036 0.0036
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0106 0.0353 0.0353
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0327 0.1176 0.1169
Loa Loa (eye worm) glutaminase 0.0199 0.0699 0.0699
Mycobacterium ulcerans DNA polymerase IV 0.0033 0.0082 0.0795
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0043 0.0028
Loa Loa (eye worm) hypothetical protein 0.0014 0.001 0.001
Echinococcus granulosus cathepsin l cysteine peptidase 0.0327 0.1176 0.1176
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0085 0.0273 0.0266
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0383 0.1384 0.1378
Loa Loa (eye worm) flap endonuclease-1 0.0026 0.0056 0.0056
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0085 0.0273 0.2256
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0017 0.0023 0.0092
Entamoeba histolytica hypothetical protein 0.018 0.063 0.061
Mycobacterium ulcerans glutaminase 0.0199 0.0699 0.7414
Schistosoma mansoni lozenge 0.0029 0.0065 0.0065
Toxoplasma gondii cathepsin CPC1 0.0085 0.0273 0.1913
Trypanosoma brucei DNA polymerase kappa, putative 0.0033 0.0082 0.0066
Schistosoma mansoni hypothetical protein 0.0037 0.0095 0.0095
Brugia malayi cathepsin B-like cysteine proteinase 0.1049 0.3865 0.3865
Giardia lamblia Cathepsin B precursor 0.0085 0.0273 0.0266
Trypanosoma brucei polo-like protein kinase 0.2695 1 1
Echinococcus multilocularis Protein lozenge 0.0029 0.0065 0.0065
Trypanosoma brucei heat shock protein, putative 0.0017 0.002 0.0005
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0229 0.081 0.0803
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0026 0.0056 0.0049
Echinococcus multilocularis lysosomal alpha glucosidase 0.0079 0.0251 0.0251
Brugia malayi photoreceptor-specific nuclear receptor 0.0106 0.0353 0.0353
Schistosoma mansoni nuclear receptor 0.005 0.0145 0.0145
Trypanosoma cruzi PAB1-binding protein , putative 0.0031 0.0074 0.0066
Brugia malayi MH2 domain containing protein 0.0047 0.0133 0.0133
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0029 0.0067 0.0067
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0106 0.0353 0.0353
Trypanosoma cruzi cysteine protease, putative 0.0183 0.0639 0.0632
Entamoeba histolytica cysteine protease, putative 0.0183 0.0639 0.062
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0038 0.01 0.0092
Trypanosoma cruzi cysteine peptidase, putative 0.0327 0.1176 0.1169
Brugia malayi Endoplasmin precursor 0.0017 0.002 0.002
Brugia malayi Cathepsin L-like precursor 0.0327 0.1176 0.1176
Schistosoma mansoni nuclear hormone receptor 0.005 0.0145 0.0145
Trichomonas vaginalis sucrase-isomaltase, putative 0.0017 0.0023 0.0015
Schistosoma mansoni Smad4 0.0047 0.0133 0.0133
Onchocerca volvulus 0.0067 0.0209 0.0209
Entamoeba histolytica cysteine protease, putative 0.0085 0.0273 0.0253
Leishmania major heat shock protein 83-1 0.0017 0.002 0.0013
Echinococcus multilocularis neuropeptide receptor A26 0.1448 0.5352 0.5352
Schistosoma mansoni ran 0.0026 0.0056 0.0056
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0034 0.0084 0.0084
Loa Loa (eye worm) hypothetical protein 0.0229 0.081 0.081
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0026 0.0056 0.0394
Loa Loa (eye worm) MBCTL1 0.0028 0.0062 0.0062
Loa Loa (eye worm) hypothetical protein 0.0085 0.0273 0.0273
Echinococcus multilocularis heat shock protein 90 0.0013 0.0008 0.0008
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0106 0.0353 0.0353
Echinococcus granulosus chromobox protein 1 0.0034 0.0083 0.0083
Entamoeba histolytica cysteine protease, putative 0.0183 0.0639 0.062
Plasmodium vivax basic transcription factor 3b, putative 0.0025 0.0052 0.036
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0085 0.0273 0.0266
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0106 0.0353 0.0353
Entamoeba histolytica cysteine protease, putative 0.0183 0.0639 0.062
Echinococcus granulosus lamin dm0 0.0035 0.009 0.009
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0654 0.2396 0.2384
Schistosoma mansoni hypothetical protein 0.0172 0.0599 0.0599
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0106 0.0353 0.0353
Entamoeba histolytica cysteine proteinase, putative 0.0183 0.0639 0.062
Echinococcus multilocularis dna polymerase eta 0.0033 0.0082 0.0082
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0022 0.004 0.004
Echinococcus multilocularis Smad4 0.0047 0.0133 0.0133
Entamoeba histolytica protein kinase domain containing protein 0.0019 0.0029 0.0008
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0654 0.2396 0.2384
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0654 0.2396 0.2384
Echinococcus multilocularis cathepsin b 0.1049 0.3865 0.3865
Echinococcus multilocularis Nuclear hormone receptor HR96 0.005 0.0145 0.0145
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.054 0.1969 0.1962
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0327 0.1176 0.1169
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.054 0.1969 0.1962
Loa Loa (eye worm) hypothetical protein 0.0229 0.081 0.081
Schistosoma mansoni sex comb on midleg homolog 0.0025 0.005 0.005
Echinococcus granulosus TGF beta signal transducer SmadC 0.0047 0.0133 0.0133
Loa Loa (eye worm) hypothetical protein 0.0025 0.005 0.005
Entamoeba histolytica cysteine protease, putative 0.0183 0.0639 0.062
Schistosoma mansoni smad 0.0047 0.0133 0.0133
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0383 0.1385 0.1385
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0327 0.1176 1
Schistosoma mansoni tar DNA-binding protein 0.0101 0.0336 0.0336
Schistosoma mansoni cathepsin F (C01 family) 0.0229 0.081 0.081
Echinococcus granulosus microtubule associated protein 2 0.1186 0.4377 0.4377
Trichomonas vaginalis CAMK family protein kinase 0.2695 1 1
Toxoplasma gondii cathepsin CPC2 0.0085 0.0273 0.1913
Brugia malayi ImpB/MucB/SamB family protein 0.0033 0.0082 0.0082
Plasmodium falciparum JmjC domain-containing protein, putative 0.0023 0.0045 0.0301
Echinococcus multilocularis insulin receptor 0.0512 0.1864 0.1864
Schistosoma mansoni sex comb on midleg homolog 0.0025 0.005 0.005
Giardia lamblia Cathepsin L precursor 0.0085 0.0273 0.0266
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0183 0.0639 0.0639
Onchocerca volvulus 0.0106 0.0353 0.0353
Schistosoma mansoni tyrosine kinase 0.0512 0.1864 0.1864
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0106 0.0353 0.0353
Echinococcus multilocularis flap endonuclease 1 0.0026 0.0056 0.0056
Giardia lamblia Hypothetical protein 0.0085 0.0273 0.0266
Onchocerca volvulus 0.0327 0.1176 0.1176
Echinococcus multilocularis 0.0494 0.18 0.18
Loa Loa (eye worm) steroid hormone receptor 0.0106 0.0353 0.0353
Onchocerca volvulus 0.0327 0.1176 0.1176
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0101 0.0334 0.0334
Schistosoma mansoni tar DNA-binding protein 0.0101 0.0336 0.0336
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0654 0.2396 0.2384
Leishmania major cathepsin L-like protease 0.0327 0.1176 0.1169
Loa Loa (eye worm) hypothetical protein 0.1049 0.3865 0.3865
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0117 0.0394 0.0394
Trypanosoma cruzi DNA polymerase kappa, putative 0.0033 0.0082 0.0074
Schistosoma mansoni cathepsin B (C01 family) 0.0085 0.0273 0.0273
Loa Loa (eye worm) hypothetical protein 0.0023 0.0045 0.0045
Onchocerca volvulus 0.0327 0.1176 0.1176
Echinococcus granulosus mothers against decapentaplegic 6 0.0021 0.0036 0.0036
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0085 0.0273 0.0266
Plasmodium vivax flap endonuclease 1, putative 0.0026 0.0056 0.039
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0025 0.005 0.005
Echinococcus granulosus transcription factor Dp 1 0.0018 0.0027 0.0027
Brugia malayi mbt repeat family protein 0.0025 0.005 0.005
Trypanosoma brucei importin beta-1 subunit, putative 0.0036 0.0092 0.0076
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0012 0.0002 0.0002
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0022 0.004 0.004
Schistosoma mansoni hypothetical protein 0.0383 0.1385 0.1385
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0034 0.0084 0.063
Trichomonas vaginalis CAMK family protein kinase 0.2695 1 1
Echinococcus multilocularis transcription factor Dp 1 0.0018 0.0027 0.0027
Trypanosoma cruzi cysteine peptidase, putative 0.0654 0.2396 0.239
Brugia malayi Ets-domain containing protein 0.0035 0.0088 0.0088
Brugia malayi cytoplasmic intermediate filament protein 0.0019 0.0029 0.0029
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0106 0.0353 0.0353
Loa Loa (eye worm) ICD-1 protein 0.0025 0.0052 0.0052
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0327 0.1176 0.1169
Echinococcus granulosus jumonji domain containing protein 0.002 0.0031 0.0031
Echinococcus multilocularis ecdysone induced protein 78C 0.0106 0.0353 0.0353
Schistosoma mansoni hypothetical protein 0.0172 0.0599 0.0599
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0106 0.0353 0.0353
Mycobacterium ulcerans DNA polymerase IV 0.0033 0.0082 0.0795
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0028 0.002
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.005 0.0145 0.0145
Echinococcus multilocularis protein dispatched 1 0.0044 0.012 0.012
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0106 0.0353 0.0353
Onchocerca volvulus Protein ultraspiracle homolog 0.0106 0.0353 0.0353
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0544 0.1985 0.1985
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0033 0.0082 0.0082
Plasmodium falciparum flap endonuclease 1 0.0026 0.0056 0.039
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0271 0.0967 0.0953
Brugia malayi RNA recognition motif domain containing protein 0.0101 0.0336 0.0336
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0085 0.0273 0.0266
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.01 0.0092
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0034 0.0084 0.0084
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0026 0.0056 0.0048
Echinococcus granulosus peregrin 0.0018 0.0026 0.0026
Trichomonas vaginalis heat shock protein, putative 0.0017 0.002 0.0013
Loa Loa (eye worm) nuclear hormone receptor 0.005 0.0145 0.0145
Onchocerca volvulus 0.004 0.0107 0.0107
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0106 0.0353 0.0353
Echinococcus multilocularis lysosomal alpha glucosidase 0.0079 0.0251 0.0251
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0026 0.0056 0.0056
Loa Loa (eye worm) hypothetical protein 0.0091 0.0298 0.0298
Echinococcus multilocularis epidermal growth factor receptor 0.1598 0.5914 0.5914
Trichomonas vaginalis CAMK family protein kinase 0.2695 1 1
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0034 0.0084 0.063
Giardia lamblia Cathepsin B precursor 0.0383 0.1384 0.1378
Brugia malayi hypothetical protein 0.0229 0.081 0.081
Trypanosoma cruzi heat shock protein 85, putative 0.0017 0.002 0.0013
Echinococcus granulosus Niemann Pick C1 protein 0.0127 0.0431 0.0431
Leishmania major heat shock protein 83-1 0.0017 0.002 0.0013
Leishmania major cathepsin L-like protease 0.0327 0.1176 0.1169
Echinococcus granulosus cathepsin L 0.0183 0.0639 0.0639
Schistosoma mansoni jumonji domain containing protein 0.0023 0.0045 0.0045
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0033 0.0082 0.0074
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0128 0.0436 0.0428
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0085 0.0273 0.0273
Plasmodium falciparum serine repeat antigen 6 0.0085 0.0273 0.2256
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0085 0.0273 0.0266
Entamoeba histolytica cysteine proteinase, putative 0.0327 0.1176 0.1158
Brugia malayi Isocitrate dehydrogenase 0.0034 0.0084 0.0084
Brugia malayi cathepsin L-like cysteine proteinase 0.0085 0.0273 0.0273
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0085 0.0273 0.0266
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1049 0.3865 0.3865
Entamoeba histolytica cysteine proteinase, putative 0.0183 0.0639 0.062
Echinococcus granulosus cysteine protease 0.0183 0.0639 0.0639
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0034 0.0084 0.0076
Brugia malayi jmjC domain containing protein 0.0091 0.0298 0.0298
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0028 0.0062 0.0062
Loa Loa (eye worm) hypothetical protein 0.0196 0.0687 0.0687
Trypanosoma brucei unspecified product 0.0023 0.0043 0.0028
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0103 0.0341 0.0341
Brugia malayi Papain family cysteine protease containing protein 0.0085 0.0273 0.0273
Loa Loa (eye worm) hypothetical protein 0.0023 0.0045 0.0045
Echinococcus multilocularis neuropeptide s receptor 0.1448 0.5352 0.5352
Onchocerca volvulus 0.0046 0.0128 0.0128
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0034 0.0084 0.0076
Trichomonas vaginalis DNA polymerase eta, putative 0.0033 0.0082 0.0074
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0017 0.0022 0.0022
Echinococcus multilocularis transcription factor btf3 0.0025 0.0052 0.0052
Trypanosoma cruzi DNA polymerase kappa, putative 0.0033 0.0082 0.0074
Brugia malayi Flap endonuclease-1 0.0026 0.0056 0.0056
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0327 0.1176 0.1169
Plasmodium vivax vivapain-3 0.0183 0.0639 0.5395
Plasmodium falciparum serine repeat antigen 9 0.0085 0.0273 0.2256
Trichomonas vaginalis alpha-glucosidase, putative 0.0017 0.0023 0.0015
Echinococcus granulosus flap endonuclease 1 0.0026 0.0056 0.0056
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0085 0.0273 0.2256
Loa Loa (eye worm) hypothetical protein 0.0056 0.0167 0.0167
Schistosoma mansoni hypothetical protein 0.0037 0.0095 0.0095
Brugia malayi hypothetical protein 0.0056 0.0167 0.0167
Echinococcus granulosus epidermal growth factor receptor 0.0859 0.316 0.316
Brugia malayi conserved hypotetical protein 0.005 0.0145 0.0145
Trypanosoma cruzi DNA polymerase kappa, putative 0.0033 0.0082 0.0074
Toxoplasma gondii isocitrate dehydrogenase 0.0034 0.0084 0.0535
Brugia malayi nuclear receptor NHR-67 0.005 0.0145 0.0145
Leishmania major DNA polymerase eta, putative 0.0033 0.0082 0.0074
Onchocerca volvulus Bile acid receptor homolog 0.0106 0.0353 0.0353
Echinococcus multilocularis Niemann Pick C1 protein 0.0089 0.0289 0.0289
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.054 0.1969 0.1952
Brugia malayi chromobox protein homolog 3 0.0019 0.0028 0.0028
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0654 0.2396 0.2384
Schistosoma mansoni patched 1 0.0038 0.01 0.01
Plasmodium falciparum ataxin-2 like protein, putative 0.0031 0.0074 0.0546
Echinococcus granulosus chromobox protein 1 0.0034 0.0083 0.0083
Trichomonas vaginalis CAMK family protein kinase 0.1334 0.4929 0.4925
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0035 0.009 0.009
Loa Loa (eye worm) nuclear factor I 0.0026 0.0055 0.0055
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0019 0.0029 0.0029
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0052 0.0045
Brugia malayi Pre-SET motif family protein 0.0062 0.0189 0.0189
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0327 0.1176 0.1169
Brugia malayi nuclear hormone receptor family member odr-7 0.005 0.0145 0.0145
Schistosoma mansoni glutaminase 0.0199 0.0699 0.0699
Echinococcus granulosus epidermal growth factor receptor 0.1598 0.5914 0.5914
Giardia lamblia Cysteine protease 0.0085 0.0273 0.0266
Brugia malayi Papain family cysteine protease containing protein 0.0183 0.0639 0.0639
Loa Loa (eye worm) MH2 domain-containing protein 0.0689 0.2524 0.2524
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0085 0.0273 0.0266
Giardia lamblia Cathepsin L-like protease 0.0085 0.0273 0.0266
Leishmania major cysteine peptidase A (CPA) 0.0327 0.1176 0.1169
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0028 0.0028
Echinococcus multilocularis JmjC domain containing protein 4 0.0023 0.0045 0.0045
Brugia malayi hypothetical protein 0.018 0.063 0.063
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0034 0.0084 0.0068
Trypanosoma cruzi cruzipain precursor, putative 0.0654 0.2396 0.239
Brugia malayi hypothetical protein 0.005 0.0145 0.0145
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0085 0.0273 0.0266
Schistosoma mansoni phosphatidylserine receptor 0.0023 0.0045 0.0045
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0327 0.1176 0.1169
Echinococcus granulosus GPCR family 2 0.0172 0.0599 0.0599
Echinococcus granulosus heat shock protein 90 0.0013 0.0008 0.0008
Echinococcus granulosus nuclear receptor nhr 48 0.005 0.0145 0.0145
Loa Loa (eye worm) hypothetical protein 0.0327 0.1176 0.1176
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0101 0.0334 0.0334
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0271 0.0967 0.096
Entamoeba histolytica Ran family GTPase 0.0026 0.0056 0.0036
Brugia malayi jmjC domain containing protein 0.0023 0.0045 0.0045
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0022 0.004 0.004
Brugia malayi Niemann-Pick C1 protein precursor 0.0089 0.0289 0.0289
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0091 0.0298 0.0298
Loa Loa (eye worm) TK/INSR protein kinase 0.0512 0.1864 0.1864
Echinococcus granulosus phd:f box containing protein 0.0023 0.0045 0.0045
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0026 0.0056 0.0056
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0106 0.0353 0.0353
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0085 0.0273 0.0273
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0085 0.0273 0.0273
Schistosoma mansoni nuclear hormone receptor 0.005 0.0145 0.0145
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0019 0.0029 0.0021
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0556 0.203 0.2024
Brugia malayi intermediate filament protein 0.0035 0.009 0.009
Trypanosoma brucei Heat shock protein 83, putative 0.0017 0.002 0.0005
Giardia lamblia Cathepsin L precursor 0.0085 0.0273 0.0266
Entamoeba histolytica cysteine protease, putative 0.0085 0.0273 0.0253
Leishmania major cathepsin L-like protease 0.0327 0.1176 0.1169
Onchocerca volvulus 0.005 0.0145 0.0145
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0017 0.0023 0.0023
Brugia malayi Ets-domain containing protein 0.0035 0.0088 0.0088
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.006 0.018 0.018
Schistosoma mansoni tyrosine kinase 0.0014 0.0009 0.0009
Brugia malayi jmjC domain containing protein 0.0117 0.0394 0.0394
Brugia malayi nuclear hormone receptor 0.005 0.0145 0.0145
Trypanosoma cruzi hypothetical protein, conserved 0.0017 0.0023 0.0015
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0654 0.2396 0.2384
Echinococcus multilocularis survival motor neuron protein 1 0.0196 0.0687 0.0687
Schistosoma mansoni hypothetical protein 0.0172 0.0599 0.0599
Echinococcus granulosus geminin 0.0656 0.2401 0.2401
Entamoeba histolytica cysteine protease, putative 0.0085 0.0273 0.0253
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0264 0.094 1
Trichomonas vaginalis importin beta-1, putative 0.0029 0.0066 0.0059
Echinococcus multilocularis PHD finger protein rhinoceros 0.0014 0.001 0.001
Trypanosoma cruzi PAB1-binding protein , putative 0.0031 0.0074 0.0066
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0026 0.0056 0.004
Entamoeba histolytica cysteine protease, putative 0.0327 0.1176 0.1158
Onchocerca volvulus 0.1042 0.384 0.384
Echinococcus granulosus PHD finger protein rhinoceros 0.0014 0.001 0.001
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0327 0.1176 0.1169
Schistosoma mansoni hypothetical protein 0.0656 0.2401 0.2401
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.054 0.1969 0.1962
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0019 0.0029 0.0135
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0544 0.1985 0.1985
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0271 0.0967 0.096
Echinococcus multilocularis SAM and MBT domain containing protein 0.0025 0.005 0.005
Entamoeba histolytica hypothetical protein 0.018 0.063 0.061
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.1049 0.3865 0.3861
Brugia malayi RNA binding protein 0.0101 0.0336 0.0336
Giardia lamblia Hypothetical protein 0.0085 0.0273 0.0266
Trichomonas vaginalis CAMK family protein kinase 0.2695 1 1
Loa Loa (eye worm) hypothetical protein 0.0098 0.0324 0.0324
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.0083 0.0266 0.0266
Leishmania major cathepsin L-like protease 0.0654 0.2396 0.239
Brugia malayi Calcitonin receptor-like protein seb-1 0.0544 0.1985 0.1985
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0017 0.0023 0.0003
Echinococcus multilocularis chromobox protein 1 0.0034 0.0083 0.0083
Loa Loa (eye worm) bromodomain containing protein 0.003 0.0071 0.0071
Loa Loa (eye worm) hypothetical protein 0.0106 0.0353 0.0353
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0032 0.0077 0.0069
Loa Loa (eye worm) hypothetical protein 0.0033 0.0082 0.0082
Trichomonas vaginalis chromobox protein, putative 0.002 0.0034 0.0026
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0327 0.1176 0.1169
Loa Loa (eye worm) hypothetical protein 0.005 0.0145 0.0145
Loa Loa (eye worm) hypothetical protein 0.0031 0.0074 0.0074
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0034 0.0084 0.0084
Trypanosoma cruzi DNA polymerase kappa, putative 0.0033 0.0082 0.0074
Schistosoma mansoni tar DNA-binding protein 0.0101 0.0336 0.0336
Brugia malayi Papain family cysteine protease containing protein 0.0327 0.1176 0.1176
Plasmodium vivax serine-repeat antigen (SERA) 0.0085 0.0273 0.2256
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0106 0.0353 0.0353
Echinococcus granulosus tyrosine protein kinase Lyn 0.0019 0.0029 0.0029
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.0028 0.0217
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0085 0.0273 0.0273
Trypanosoma cruzi ISWI complex protein 0.0026 0.0056 0.0048
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0062 0.0189 0.0189
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0022 0.004 0.004
Loa Loa (eye worm) runx1 0.0029 0.0065 0.0065
Echinococcus granulosus tar DNA binding protein 0.0101 0.0336 0.0336
Mycobacterium ulcerans hypothetical protein 0.0143 0.049 0.5167
Echinococcus granulosus neutral alpha glucosidase AB 0.0017 0.0023 0.0023
Onchocerca volvulus 0.0327 0.1176 0.1176
Schistosoma mansoni tyrosine kinase 0.0849 0.3122 0.3122
Trypanosoma cruzi cysteine peptidase, putative 0.0654 0.2396 0.239
Loa Loa (eye worm) glutaminase 2 0.0199 0.0699 0.0699
Schistosoma mansoni tyrosine kinase 0.0512 0.1864 0.1864
Leishmania major heat shock protein 83-1 0.0017 0.002 0.0013
Echinococcus granulosus cathepsin l1 0.0229 0.081 0.081
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0106 0.0353 0.0353
Echinococcus granulosus intermediate filament protein 0.0035 0.009 0.009
Entamoeba histolytica transcription factor BTF3, putative 0.0025 0.0052 0.0032
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0033 0.0082 0.0074
Loa Loa (eye worm) hypothetical protein 0.0172 0.0599 0.0599
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0327 0.1176 0.1169
Toxoplasma gondii NAC domain-containing protein 0.0025 0.0052 0.0305
Trichomonas vaginalis CAMK family protein kinase 0.1334 0.4929 0.4925
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0032 0.0077 0.0077
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0028 0.002
Plasmodium falciparum serine repeat antigen 2 0.0085 0.0273 0.2256
Echinococcus granulosus jumonji domain containing 1A 0.0023 0.0045 0.0045
Plasmodium vivax vivapain-1 0.0183 0.0639 0.5395
Loa Loa (eye worm) hypothetical protein 0.005 0.0145 0.0145
Schistosoma mansoni protein phosphatase 2C 0.0023 0.0045 0.0045
Giardia lamblia Cathepsin L precursor 0.0085 0.0273 0.0266
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0026 0.0056 0.0049
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0028 0.0012
Echinococcus multilocularis epidermal growth factor receptor 0.0859 0.316 0.316
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0067 0.0209 0.0209
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.054 0.1969 0.1962
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0019 0.0029 0.0021
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0052 0.0045
Onchocerca volvulus 0.0327 0.1176 0.1176
Trypanosoma brucei glucosidase, putative 0.0017 0.0023 0.0007
Plasmodium falciparum protein kinase, putative 0.0019 0.0029 0.0159
Entamoeba histolytica cysteine proteinase, putative 0.0183 0.0639 0.062
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0264 0.094 1
Leishmania major basic transcription factor 3a, putative 0.0025 0.0052 0.0045
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0038 0.01 0.0092
Brugia malayi MH2 domain containing protein 0.0021 0.0036 0.0036
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0023 0.0045 0.0045
Trypanosoma cruzi transcription factor btf3, putative 0.0025 0.0052 0.0045
Leishmania major heat shock protein 83-1 0.0017 0.002 0.0013
Plasmodium vivax serine-repeat antigen (SERA) 0.0085 0.0273 0.2256
Brugia malayi nuclear hormone receptor 0.0106 0.0353 0.0353
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0023 0.0045 0.0255
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0017 0.0023 0.0015
Echinococcus granulosus fetal alzheimer antigen falz 0.0039 0.0103 0.0103
Toxoplasma gondii heat shock protein 90, putative 0.0017 0.002 0.0073
Loa Loa (eye worm) heat shock protein 90 0.0017 0.002 0.002
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0106 0.0353 0.0353
Onchocerca volvulus Cathepsin L homolog 0.0327 0.1176 0.1176
Entamoeba histolytica hypothetical protein 0.018 0.063 0.061
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0327 0.1176 0.1169
Schistosoma mansoni smad 0.0021 0.0036 0.0036
Trypanosoma brucei transcription factor BTF3, putative 0.0025 0.0052 0.0036
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0022 0.004 0.004
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0028 0.0062 0.0062
Trichomonas vaginalis alpha-glucosidase, putative 0.0017 0.0023 0.0015
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0028 0.002
Echinococcus granulosus sterol regulatory element binding protein 0.0038 0.01 0.01
Loa Loa (eye worm) hypothetical protein 0.007 0.022 0.022
Toxoplasma gondii isocitrate dehydrogenase 0.0034 0.0084 0.0535
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0017 0.0022 0.0022
Echinococcus multilocularis microtubule associated protein 2 0.1186 0.4377 0.4377
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0056 0.0167 0.0167
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0106 0.0353 0.0353
Echinococcus multilocularis peregrin 0.0018 0.0026 0.0026
Brugia malayi nuclear hormone receptor family member nhr-6 0.005 0.0145 0.0145
Brugia malayi Bromodomain containing protein 0.0018 0.0026 0.0026
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0098 0.0324 0.0324
Loa Loa (eye worm) hypothetical protein 0.0085 0.0273 0.0273
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0106 0.0353 0.0353
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0029 0.0067 0.0067
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0106 0.0353 0.0353
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0101 0.0336 0.0336
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0106 0.0353 0.0353
Brugia malayi jmjC domain containing protein 0.0023 0.0045 0.0045
Schistosoma mansoni tyrosine kinase 0.0173 0.0601 0.0601
Onchocerca volvulus 0.0035 0.009 0.009
Loa Loa (eye worm) hypothetical protein 0.1042 0.384 0.384
Loa Loa (eye worm) jmjC domain-containing protein 0.0023 0.0045 0.0045
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0183 0.0639 0.0632
Plasmodium vivax unspecified product 0.0183 0.0639 0.5395
Brugia malayi cathepsin L precursor 0.0085 0.0273 0.0273
Echinococcus granulosus smad 0.0047 0.0133 0.0133
Trypanosoma brucei PAB1-binding protein , putative 0.0031 0.0074 0.0058
Brugia malayi hypothetical protein 0.005 0.0145 0.0145
Brugia malayi beta-NAC-like protein 0.0025 0.0052 0.0052
Schistosoma mansoni endoplasmin 0.0017 0.002 0.002
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0432 0.1568 0.1568
Echinococcus granulosus zinc finger protein 0.0034 0.0084 0.0084
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0019 0.0028 1
Loa Loa (eye worm) hypothetical protein 0.0085 0.0273 0.0273
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0038 0.01 0.0084
Brugia malayi isocitrate dehydrogenase 0.0034 0.0084 0.0084
Onchocerca volvulus Cathepsin L homolog 0.0327 0.1176 0.1176
Brugia malayi TAR-binding protein 0.0101 0.0336 0.0336
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0183 0.0639 0.0639
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0028 0.0021
Echinococcus granulosus importin subunit beta 1 0.0036 0.0092 0.0092
Echinococcus multilocularis nuclear receptor nhr 48 0.005 0.0145 0.0145
Trypanosoma cruzi heat shock protein 85, putative 0.0017 0.002 0.0013
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0327 0.1176 0.1169
Giardia lamblia Cysteine protease 0.0085 0.0273 0.0266
Trypanosoma cruzi importin beta-1 subunit, putative 0.0029 0.0066 0.0059
Schistosoma mansoni hypothetical protein 0.0036 0.009 0.009
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0014 0.001 0.001
Brugia malayi Probable ATP-dependent helicase DHX35 0.0118 0.0396 0.0396
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0327 0.1176 0.1169
Trypanosoma cruzi Heat shock protein 83, putative 0.0017 0.002 0.0013
Leishmania major heat shock protein 83-1 0.0017 0.002 0.0013
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0046 0.0131 0.0123
Loa Loa (eye worm) hypothetical protein 0.0229 0.081 0.081
Plasmodium falciparum serine repeat antigen 5 0.0085 0.0273 0.2256
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0128 0.0436 0.0428
Loa Loa (eye worm) hypothetical protein 0.0118 0.0396 0.0396
Loa Loa (eye worm) TK/EGFR protein kinase 0.1598 0.5914 0.5914
Trichomonas vaginalis ran, putative 0.0026 0.0056 0.0049
Brugia malayi Cathepsin L-like cysteine proteinase 0.0229 0.081 0.081
Entamoeba histolytica cysteine protease, putative 0.0183 0.0639 0.062
Plasmodium falciparum heat shock protein 90 0.0017 0.002 0.0086
Trichomonas vaginalis CAMK family protein kinase 0.2695 1 1
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0027 0.0058 0.0058
Loa Loa (eye worm) hypothetical protein 0.0056 0.0167 0.0167
Loa Loa (eye worm) hypothetical protein 0.0038 0.01 0.01
Trypanosoma brucei DNA polymerase IV, putative 0.0033 0.0082 0.0066
Schistosoma mansoni Smad4 0.0021 0.0036 0.0036
Loa Loa (eye worm) apoptosis regulator protein 0.0083 0.0266 0.0266
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0085 0.0273 0.0266
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0106 0.0353 0.0353
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0654 0.2396 0.2384
Onchocerca volvulus Cathepsin L homolog 0.0085 0.0273 0.0273
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.005 0.0145 0.0145
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0039 0.0103 0.0103
Loa Loa (eye worm) hypothetical protein 0.0106 0.0353 0.0353
Loa Loa (eye worm) hypothetical protein 0.0106 0.0353 0.0353
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0085 0.0273 0.0266
Brugia malayi Cathepsin L-like precursor 0.0327 0.1176 0.1176
Echinococcus multilocularis cathepsin L 0.0183 0.0639 0.0639
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0056 0.0167 0.0167
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0085 0.0273 0.0266
Plasmodium vivax endoplasmin, putative 0.0017 0.002 0.0086
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0034 0.0084 0.0816
Schistosoma mansoni steroid hormone receptor ad4bp 0.0106 0.0353 0.0353
Leishmania major alpha glucosidase II subunit, putative 0.0017 0.0023 0.0015
Treponema pallidum exodeoxyribonuclease (exoA) 0.0019 0.0028 0.0103
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.0083 0.0266 0.0266
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.054 0.1969 0.1962
Echinococcus multilocularis cathepsin b 0.1049 0.3865 0.3865
Echinococcus granulosus neuropeptide receptor A26 0.1448 0.5352 0.5352
Trypanosoma brucei heat shock protein, putative 0.0017 0.002 0.0005
Trypanosoma brucei DNA polymerase IV, putative 0.0033 0.0082 0.0066
Echinococcus granulosus thyroid hormone receptor alpha 0.005 0.0145 0.0145
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0025 0.005 0.005
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0019 0.0029 0.0013
Echinococcus granulosus activin receptor type 0.0019 0.0029 0.0029
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0091 0.0298 0.0298
Plasmodium vivax unspecified product 0.0085 0.0273 0.2256
Entamoeba histolytica cysteine protease, putative 0.0183 0.0639 0.062
Brugia malayi Intermediate filament tail domain containing protein 0.0035 0.009 0.009
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0106 0.0353 0.0353
Brugia malayi Pre-SET motif family protein 0.0432 0.1568 0.1568
Echinococcus granulosus mothers against decapentaplegic 5 0.0047 0.0133 0.0133
Loa Loa (eye worm) jmjC domain-containing protein 0.0029 0.0066 0.0066
Echinococcus granulosus Niemann Pick C1 protein 0.0089 0.0289 0.0289
Echinococcus multilocularis protein tyrosine kinase 0.0173 0.0601 0.0601
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0183 0.0639 0.0632
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0034 0.0084 0.0068
Echinococcus granulosus expressed conserved protein 0.0083 0.0269 0.0269
Echinococcus multilocularis FTZ F1 alpha 0.0106 0.0353 0.0353
Plasmodium falciparum basic transcription factor 3b, putative 0.0025 0.0052 0.036
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.018 0.063 0.063
Brugia malayi Steroid receptor seven-up type 2 0.0106 0.0353 0.0353
Schistosoma mansoni heat shock protein 0.0017 0.002 0.002
Schistosoma mansoni alpha-glucosidase 0.0068 0.021 0.021
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.0083 0.0266 0.0266
Schistosoma mansoni coup transcription factor 0.0106 0.0353 0.0353
Trichomonas vaginalis alpha-glucosidase, putative 0.0017 0.0023 0.0015
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0172 0.0599 0.0599
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0019 0.0028 0.0028
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0085 0.0273 0.0273
Plasmodium falciparum serine repeat antigen 7 0.0085 0.0273 0.2256
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0028 0.002
Trypanosoma brucei heat shock protein, putative 0.0017 0.002 0.0005
Brugia malayi Nuclear hormone receptor E75 0.005 0.0145 0.0145
Echinococcus granulosus lysine specific demethylase 6a 0.0023 0.0045 0.0045
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0026 0.0056 0.0056
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0327 0.1176 0.1169
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0034 0.0084 0.0084
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0327 0.1176 0.1176
Trichomonas vaginalis heat shock protein, putative 0.0013 0.0008 0.0000027188
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0062 0.0189 0.1299
Onchocerca volvulus 0.0015 0.0013 0.0013
Loa Loa (eye worm) nuclear receptor NHR-67 0.005 0.0145 0.0145
Leishmania major heat shock protein 83-1 0.0017 0.002 0.0013
Brugia malayi Bromodomain containing protein 0.0129 0.044 0.044
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0047 0.0133 0.0133
Trypanosoma brucei importin beta-1 subunit, putative 0.0036 0.0092 0.0076
Echinococcus multilocularis mothers against decapentaplegic 6 0.0021 0.0036 0.0036
Schistosoma mansoni smad1 5 8 and 0.0047 0.0133 0.0133
Echinococcus multilocularis mothers against decapentaplegic 5 0.0047 0.0133 0.0133
Onchocerca volvulus Mothers against decapentaplegic homolog 0.0021 0.0036 0.0036
Echinococcus granulosus heat shock protein 0.0017 0.002 0.002
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0085 0.0273 0.0266
Schistosoma mansoni protein kinase 0.0019 0.0029 0.0029
Entamoeba histolytica cysteine protease, putative 0.0183 0.0639 0.062
Loa Loa (eye worm) hypothetical protein 0.0083 0.0266 0.0266
Schistosoma mansoni bromodomain containing protein 0.0109 0.0364 0.0364
Trichomonas vaginalis chromobox protein, putative 0.0034 0.0083 0.0076
Leishmania major cathepsin L-like protease 0.0327 0.1176 0.1169
Entamoeba histolytica serine/threonine protein kinase, putative 0.2695 1 1
Brugia malayi glutaminase DH11.1 0.0199 0.0699 0.0699
Brugia malayi orphan nuclear receptor NR2E1 0.005 0.0145 0.0145
Trypanosoma cruzi DNA polymerase eta, putative 0.0033 0.0082 0.0074
Brugia malayi Latrophilin receptor protein 2 0.0172 0.0599 0.0599
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0383 0.1384 0.1384
Brugia malayi hypothetical protein 0.0056 0.0167 0.0167
Trichomonas vaginalis heat shock protein, putative 0.0013 0.0008 0.0000027188
Echinococcus multilocularis geminin 0.0656 0.2401 0.2401
Loa Loa (eye worm) hypothetical protein 0.0106 0.0353 0.0353
Brugia malayi Cathepsin L-like precursor 0.0327 0.1176 0.1176
Loa Loa (eye worm) PHD-finger family protein 0.0014 0.001 0.001
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0056 0.0167 0.0167
Brugia malayi ecdysteroid receptor 0.0106 0.0353 0.0353
Loa Loa (eye worm) ctsf protein 0.0327 0.1176 0.1176
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0327 0.1176 0.1169
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.004 0.0107 0.0107
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0327 0.1176 0.1169
Giardia lamblia Cathepsin L-like protease 0.0085 0.0273 0.0266
Schistosoma mansoni intermediate filament proteins 0.0035 0.009 0.009
Echinococcus granulosus lysosomal alpha glucosidase 0.0079 0.0251 0.0251
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0027 0.0058 0.0058
Echinococcus multilocularis sterol regulatory element binding protein 0.0038 0.01 0.01
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0107 0.0357 0.0357
Loa Loa (eye worm) latrophilin receptor protein 2 0.0172 0.0599 0.0599
Loa Loa (eye worm) hypothetical protein 0.0016 0.0019 0.0019
Trypanosoma brucei ISWI complex protein 0.0026 0.0056 0.004
Toxoplasma gondii hypothetical protein 0.0044 0.0121 0.0803
Trypanosoma cruzi cysteine peptidase, putative 0.0183 0.0639 0.0632
Echinococcus multilocularis thyroid hormone receptor alpha 0.0106 0.0353 0.0353
Schistosoma mansoni tyrosine kinase 0.0859 0.316 0.316
Echinococcus multilocularis lysine specific demethylase 5A 0.0088 0.0286 0.0286
Loa Loa (eye worm) hypothetical protein 0.0106 0.0353 0.0353
Brugia malayi MH2 domain containing protein 0.0047 0.0133 0.0133
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0013 0.0008 0.0008
Plasmodium vivax ataxin-2 like protein, putative 0.0031 0.0074 0.0546
Loa Loa (eye worm) hypothetical protein 0.0026 0.0055 0.0055
Brugia malayi hypothetical protein 0.0196 0.0687 0.0687
Echinococcus granulosus cathepsin L cysteine protease 0.0183 0.0639 0.0639
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0106 0.0353 0.0353
Loa Loa (eye worm) jmjC domain-containing protein 0.0023 0.0045 0.0045
Brugia malayi jmjC domain containing protein 0.0023 0.0045 0.0045
Brugia malayi nuclear receptor RXR 0.0056 0.0167 0.0167
Echinococcus multilocularis chromobox protein 1 0.0034 0.0083 0.0083
Brugia malayi Nuclear hormone receptor-like 1 0.0056 0.0167 0.0167
Brugia malayi tailless protein 0.005 0.0145 0.0145
Loa Loa (eye worm) DEAH box polypeptide 35 0.0118 0.0396 0.0396
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0106 0.0353 0.0353
Echinococcus granulosus serine:threonine protein kinase PLK1 0.2695 1 1
Plasmodium falciparum importin beta, putative 0.0036 0.0092 0.0697
Plasmodium vivax vivapain-2 0.0327 0.1176 1
Brugia malayi Immunoglobulin I-set domain containing protein 0.0107 0.0357 0.0357
Giardia lamblia DINP protein human, muc B family 0.0033 0.0082 0.0074
Entamoeba histolytica hypothetical protein 0.018 0.063 0.061
Leishmania major GTP-binding protein, putative 0.0026 0.0056 0.0049
Schistosoma mansoni tyrosine kinase 0.1598 0.5914 0.5914
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0327 0.1176 0.1169
Echinococcus multilocularis neutral alpha glucosidase AB 0.0017 0.0023 0.0023
Schistosoma mansoni lamin 0.0035 0.009 0.009
Echinococcus granulosus transcription factor btf3 0.0025 0.0052 0.0052
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0183 0.0639 0.0624
Trichomonas vaginalis set domain proteins, putative 0.0492 0.1791 0.1784
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0264 0.094 1
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0098 0.0324 0.0324
Trypanosoma brucei heat shock protein, putative 0.0017 0.002 0.0005
Onchocerca volvulus 0.0492 0.1791 0.1791
Echinococcus granulosus GTP binding nuclear protein Ran 0.0026 0.0056 0.0056
Leishmania major heat shock protein 83-1 0.0017 0.002 0.0013
Trypanosoma brucei DNA polymerase kappa, putative 0.0033 0.0082 0.0066
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0014 0.001 0.001
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0085 0.0273 0.0273
Loa Loa (eye worm) MH1 domain-containing protein 0.0047 0.0133 0.0133
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.005 0.0145 0.0145
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0183 0.0639 0.0639
Trichomonas vaginalis maltase-glucoamylase, putative 0.0017 0.0023 0.0015
Loa Loa (eye worm) hypothetical protein 0.0085 0.0273 0.0273
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0106 0.0353 0.0353
Schistosoma mansoni zinc finger protein 0.0026 0.0056 0.0056
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0035 0.0088 0.0088
Trichomonas vaginalis chromobox protein, putative 0.002 0.0034 0.0026
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0019 0.0029 0.0029
Entamoeba histolytica cysteine proteinase 1, putative 0.0183 0.0639 0.062
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0028 0.0028
Loa Loa (eye worm) hypothetical protein 0.0066 0.0204 0.0204
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0022 0.004 0.004
Loa Loa (eye worm) TK/FAK protein kinase 0.0174 0.0608 0.0608
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.2695 1 1
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0085 0.0273 0.0253
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0085 0.0273 0.0266
Plasmodium falciparum cysteine proteinase falcipain 1 0.0183 0.0639 0.5395
Trypanosoma cruzi cruzipain precursor, putative 0.0098 0.0324 0.0316
Loa Loa (eye worm) hypothetical protein 0.005 0.0145 0.0145
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0327 0.1176 0.1169
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0085 0.0273 0.2256
Loa Loa (eye worm) hypothetical protein 0.005 0.0145 0.0145
Toxoplasma gondii cathepsin CPL 0.0327 0.1176 0.8483
Leishmania major importin beta-1 subunit, putative 0.0029 0.0066 0.0059
Brugia malayi heat shock protein 90 0.0017 0.002 0.002
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0032 0.0077 0.0077
Schistosoma mansoni ap endonuclease 0.0019 0.0028 0.0028
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0106 0.0353 0.0353
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.0083 0.0266 0.0266
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.005 0.0145 0.0145
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.2508 0.9303 0.9303
Trypanosoma brucei DNA polymerase kappa, putative 0.0033 0.0082 0.0066
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0023 0.0045 0.003
Brugia malayi latrophilin 2 splice variant baaae 0.0372 0.1344 0.1344
Loa Loa (eye worm) hypothetical protein 0.005 0.0145 0.0145
Echinococcus granulosus dna polymerase kappa 0.0033 0.0082 0.0082
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0026 0.0056 0.0331
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0106 0.0353 0.0353
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0085 0.0273 0.2256
Schistosoma mansoni protein kinase 0.0019 0.0029 0.0029
Schistosoma mansoni alpha glucosidase 0.0017 0.0023 0.0023
Trypanosoma brucei DNA polymerase kappa, putative 0.0033 0.0082 0.0066
Brugia malayi cathepsin Z-like cysteine proteinase 0.0085 0.0273 0.0273
Trypanosoma brucei DNA polymerase kappa, putative 0.0033 0.0082 0.0066
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0383 0.1384 0.1378
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0052 0.0045
Brugia malayi Cathepsin L-like precursor 0.0229 0.081 0.081
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0085 0.0273 0.0266
Entamoeba histolytica hypothetical protein 0.0085 0.0273 0.0253
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0028 0.0151
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.1049 0.3865 0.3865
Echinococcus multilocularis cathepsin L cysteine protease 0.0327 0.1176 0.1176
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0034 0.0084 0.0084
Echinococcus granulosus insulin receptor 0.0512 0.1864 0.1864
Loa Loa (eye worm) hypothetical protein 0.0056 0.0167 0.0167
Brugia malayi CHE-14 protein 0.0038 0.01 0.01
Schistosoma mansoni myelin transcription factor 1 myt1 0.0028 0.0062 0.0062
Leishmania major heat shock protein 83-1 0.0017 0.002 0.0013
Loa Loa (eye worm) hypothetical protein 0.005 0.0145 0.0145
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0229 0.081 0.0803
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.0083 0.0266 0.0266
Entamoeba histolytica cysteine protease, putative 0.0183 0.0639 0.062
Echinococcus granulosus FTZ F1 alpha 0.0106 0.0353 0.0353
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0028 0.0028
Plasmodium vivax JmjC domain containing protein 0.0023 0.0045 0.0301
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0023 0.0045 0.0038
Loa Loa (eye worm) hypothetical protein 0.005 0.0145 0.0145
Brugia malayi Bromodomain containing protein 0.0066 0.0204 0.0204
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0026 0.0056 0.0394
Entamoeba histolytica cysteine protease, putative 0.0085 0.0273 0.0253
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0028 0.0151
Echinococcus granulosus histone lysine methyltransferase setb 0.0091 0.0298 0.0298
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0106 0.0353 0.0353
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0032 0.0077 0.0069
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0019 0.0028 0.0008
Trichomonas vaginalis alpha-glucosidase, putative 0.0017 0.0023 0.0015
Giardia lamblia Cathepsin B precursor 0.0085 0.0273 0.0266
Echinococcus multilocularis Niemann Pick C1 protein 0.0127 0.0431 0.0431
Schistosoma mansoni importin beta-1 0.0036 0.0092 0.0092
Echinococcus multilocularis endoplasmin 0.0013 0.0008 0.0008
Schistosoma mansoni retinoic acid receptor RXR 0.0106 0.0353 0.0353
Loa Loa (eye worm) PHD-finger family protein 0.0036 0.009 0.009
Trypanosoma cruzi polo-like protein kinase, putative 0.2695 1 1
Schistosoma mansoni nuclear receptor 0.005 0.0145 0.0145
Onchocerca volvulus Heterochromatin protein 1 homolog 0.002 0.0034 0.0034
Brugia malayi ecdysone receptor 0.005 0.0145 0.0145
Brugia malayi Immunoglobulin I-set domain containing protein 0.0012 0.0002 0.0002
Schistosoma mansoni lamin 0.0035 0.009 0.009
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0085 0.0273 0.0266
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0033 0.0082 0.0082
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0172 0.0599 0.0599
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0085 0.0273 0.0273
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0183 0.0639 0.0632
Schistosoma mansoni Smad4 0.0021 0.0036 0.0036
Schistosoma mansoni chromobox protein 0.0034 0.0083 0.0083
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0172 0.0599 0.0599
Loa Loa (eye worm) hypothetical protein 0.005 0.0145 0.0145
Echinococcus granulosus Nuclear hormone receptor HR96 0.005 0.0145 0.0145
Loa Loa (eye worm) TK/ROR protein kinase 0.0012 0.0002 0.0002
Mycobacterium ulcerans aldehyde dehydrogenase 0.0029 0.0067 0.0638
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0029 0.0066 0.0059
Echinococcus multilocularis jumonji domain containing protein 0.002 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0056 0.0167 0.0167
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.005 0.0145 0.0145
Echinococcus multilocularis importin subunit beta 1 0.0036 0.0092 0.0092
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0085 0.0273 0.2256
Loa Loa (eye worm) fibroinase 0.0327 0.1176 0.1176
Brugia malayi Glycosyl hydrolases family 31 protein 0.0017 0.0023 0.0023
Echinococcus granulosus JmjC domain containing protein 4 0.0023 0.0045 0.0045
Schistosoma mansoni hypothetical protein 0.018 0.063 0.063
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0106 0.0353 0.0353
Loa Loa (eye worm) hypothetical protein 0.0016 0.0019 0.0019
Trichomonas vaginalis flap endonuclease-1, putative 0.0026 0.0056 0.0048
Loa Loa (eye worm) mbt repeat family protein 0.0025 0.005 0.005
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0383 0.1384 0.1378
Loa Loa (eye worm) hypothetical protein 0.0036 0.0092 0.0092
Trypanosoma brucei DNA polymerase kappa, putative 0.0033 0.0082 0.0066
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0085 0.0273 0.0266
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0085 0.0273 0.2256
Plasmodium vivax unspecified product 0.0098 0.0324 0.2689
Onchocerca volvulus Tyrosine kinase homolog 0.0101 0.0333 0.0333
Plasmodium vivax importin-beta 2, putative 0.0036 0.0092 0.0697
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0106 0.0353 0.0353
Schistosoma mansoni jumonji/arid domain-containing protein 0.0091 0.0298 0.0298
Entamoeba histolytica cysteine protease, putative 0.0183 0.0639 0.062
Schistosoma mansoni RAR-like nuclear receptor 0.0106 0.0353 0.0353
Schistosoma mansoni cathepsin F (C01 family) 0.0327 0.1176 0.1176
Trypanosoma cruzi heat shock protein 90, putative 0.0017 0.002 0.0013
Echinococcus granulosus neuropeptide s receptor 0.1448 0.5352 0.5352
Loa Loa (eye worm) hypothetical protein 0.0017 0.0022 0.0022
Trypanosoma brucei unspecified product 0.0023 0.0043 0.0028
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0859 0.316 0.316
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.0083 0.0266 0.0266
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0043 0.0028
Echinococcus granulosus mothers against decapentaplegic 2 0.0021 0.0036 0.0036
Echinococcus granulosus twitchin 0.0016 0.0019 0.0019
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0019 0.0029 0.0029
Brugia malayi hypothetical protein 0.002 0.0033 0.0033
Schistosoma mansoni cathepsin F (C01 family) 0.0327 0.1176 0.1176
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0026 0.0056 0.0334
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.005 0.0145 0.0145
Leishmania major mitochondrial DNA polymerase beta 0.0271 0.0967 0.096
Leishmania major heat shock protein 83-1 0.0017 0.002 0.0013
Toxoplasma gondii LsmAD domain-containing protein 0.0031 0.0074 0.0463
Giardia lamblia PHD finger protein 15 0.0014 0.001 0.0003
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0017 0.0023 0.0003
Toxoplasma gondii cathepsin B 0.0383 0.1384 1
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0327 0.1176 0.1176
Entamoeba histolytica cysteine protease, putative 0.0183 0.0639 0.062
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1049 0.3865 0.3865
Echinococcus granulosus Nuclear hormone receptor HR96 0.005 0.0145 0.0145
Loa Loa (eye worm) hypothetical protein 0.0089 0.0289 0.0289
Brugia malayi Furin-like cysteine rich region family protein 0.1598 0.5914 0.5914
Loa Loa (eye worm) TAR-binding protein 0.0101 0.0336 0.0336
Schistosoma mansoni serine/threonine protein kinase 0.2695 1 1
Plasmodium falciparum serine repeat antigen 8 0.0085 0.0273 0.2256
Loa Loa (eye worm) hypothetical protein 0.0085 0.0273 0.0273
Leishmania major heat shock protein 83-1 0.0017 0.002 0.0013
Loa Loa (eye worm) MH2 domain-containing protein 0.0047 0.0133 0.0133
Brugia malayi MH1 domain containing protein 0.0047 0.0133 0.0133
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0014 0.001 0.001
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0033 0.0082 0.0082
Loa Loa (eye worm) nuclear receptor nhr-7B 0.005 0.0145 0.0145
Treponema pallidum fructose-bisphosphate aldolase 0.054 0.1969 1
Schistosoma mansoni nuclear receptor nhr-48 0.005 0.0145 0.0145
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0128 0.0436 0.042
Loa Loa (eye worm) hypothetical protein 0.0122 0.0412 0.0412
Entamoeba histolytica deoxycytidyl transferase, putative 0.0033 0.0082 0.0062
Schistosoma mansoni hypothetical protein 0.0656 0.2401 0.2401
Loa Loa (eye worm) cysteine protease 0.0327 0.1176 0.1176
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0327 0.1176 0.1169
Loa Loa (eye worm) hypothetical protein 0.0098 0.0324 0.0324
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0028 0.0021
Echinococcus granulosus heat shock protein 90 0.0017 0.002 0.002
Echinococcus granulosus GA binding protein alpha chain 0.0035 0.0088 0.0088
Mycobacterium tuberculosis Conserved hypothetical protein 0.0143 0.049 0.5167
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0056 0.0167 0.0167
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0026 0.0056 0.004
Brugia malayi Heterochromatin protein 1 0.0034 0.0083 0.0083
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0029 0.0067 0.0067
Loa Loa (eye worm) hypothetical protein 0.0544 0.1985 0.1985
Loa Loa (eye worm) fli-1 protein 0.0106 0.0354 0.0354
Loa Loa (eye worm) hypothetical protein 0.0021 0.0036 0.0036
Schistosoma mansoni microtubule-associated protein tau 0.1186 0.4377 0.4377
Echinococcus granulosus nuclear receptor 2DBD gamma 0.005 0.0145 0.0145
Mycobacterium ulcerans aldehyde dehydrogenase 0.0029 0.0067 0.0638
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0029 0.0067 0.006
Schistosoma mansoni hypothetical protein 0.0026 0.0056 0.0056
Onchocerca volvulus Cathepsin F homolog 0.0327 0.1176 0.1176
Loa Loa (eye worm) cathepsin B 0.0383 0.1384 0.1384
Echinococcus granulosus histone acetyltransferase MYST2 0.0028 0.0062 0.0062
Schistosoma mansoni methyl-cpg binding protein mbd 0.0029 0.0067 0.0067
Loa Loa (eye worm) hypothetical protein 0.0047 0.0132 0.0132
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0106 0.0353 0.0353
Loa Loa (eye worm) TK protein kinase 0.0012 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0372 0.1344 0.1344
Leishmania major hypothetical protein, conserved 0.0031 0.0074 0.0066
Onchocerca volvulus 0.0327 0.1176 0.1176
Leishmania major heat shock protein 83-1 0.0017 0.002 0.0013
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0023 0.0045 0.0038
Trypanosoma brucei DNA polymerase kappa, putative 0.0033 0.0082 0.0066
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0022 0.004 0.004
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0085 0.0273 0.0273
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0106 0.0353 0.0353
Brugia malayi Nuclear hormone receptor-like 1 0.0106 0.0353 0.0353
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0022 0.004 0.004
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0106 0.0353 0.0353
Schistosoma mansoni phd/f-box containing protein 0.0023 0.0045 0.0045
Schistosoma mansoni smad1 5 8 and 0.0047 0.0133 0.0133
Echinococcus multilocularis cysteine protease 0.0327 0.1176 0.1176
Leishmania major heat shock protein 83-1 0.0017 0.002 0.0013
Echinococcus granulosus snurportin 1 0.0383 0.1385 0.1385
Entamoeba histolytica cysteine proteinase, putative 0.0229 0.081 0.0791
Brugia malayi MH2 domain containing protein 0.0689 0.2524 0.2524
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0032 0.0077 0.0077
Echinococcus multilocularis histone acetyltransferase MYST2 0.0028 0.0062 0.0062
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0172 0.0599 0.0599
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0017 0.0023 0.0015
Schistosoma mansoni cathepsin s 0.0098 0.0324 0.0324
Leishmania major hypothetical protein, conserved 0.0023 0.0045 0.0038
Trypanosoma cruzi hypothetical protein, conserved 0.0017 0.0023 0.0015
Schistosoma mansoni smad1 5 8 and 0.0047 0.0133 0.0133
Plasmodium vivax vivapain-2 0.0327 0.1176 1
Loa Loa (eye worm) transcription factor SMAD2 0.0689 0.2524 0.2524
Echinococcus multilocularis protein patched 0.0038 0.01 0.01
Giardia lamblia Cathepsin B precursor 0.0085 0.0273 0.0266
Giardia lamblia Cathepsin L precursor 0.0085 0.0273 0.0266
Schistosoma mansoni hypothetical protein 0.0037 0.0095 0.0095
Loa Loa (eye worm) hypothetical protein 0.0019 0.0028 0.0028
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0062 0.0189 0.0189
Mycobacterium tuberculosis Conserved hypothetical protein 0.0033 0.0082 0.0795
Echinococcus multilocularis dna polymerase kappa 0.0033 0.0082 0.0082
Trypanosoma cruzi cysteine proteinase, putative 0.0183 0.0639 0.0632
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0106 0.0353 0.0353
Giardia lamblia Cathepsin B precursor 0.0085 0.0273 0.0266
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0085 0.0273 0.0273
Trichomonas vaginalis CAMK family protein kinase 0.2695 1 1
Brugia malayi Protein kinase domain containing protein 0.0512 0.1864 0.1864
Leishmania major heat shock protein 83-1 0.0017 0.002 0.0013
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0172 0.0599 0.0599
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0032 0.0077 0.0077
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0654 0.2396 0.2384
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0085 0.0273 0.0266
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0038 0.01 0.0092
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0038 0.01 0.01
Brugia malayi Cathepsin L-like precursor 0.0327 0.1176 0.1176
Echinococcus multilocularis lamin dm0 0.0035 0.009 0.009
Onchocerca volvulus 0.0229 0.081 0.081
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.2695 1 1
Schistosoma mansoni ran 0.0026 0.0056 0.0056
Plasmodium vivax heat shock protein 86, putative 0.0017 0.002 0.0086
Schistosoma mansoni tyrosine kinase 0.0849 0.3122 0.3122
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0117 0.0394 0.0394
Schistosoma mansoni hypothetical protein 0.0083 0.0266 0.0266
Loa Loa (eye worm) hypothetical protein 0.0015 0.0013 0.0013
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0085 0.0273 0.2256
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0028 0.0062 0.0062
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.005 0.0145 0.0145
Trypanosoma cruzi transcription factor btf3, putative 0.0025 0.0052 0.0045
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.054 0.1969 0.1962
Brugia malayi cathepsin L-like precursor 0.0229 0.081 0.081
Giardia lamblia Fructose-bisphosphate aldolase 0.054 0.1969 0.1962
Trichomonas vaginalis CAMK family protein kinase 0.2695 1 1
Brugia malayi Cathepsin L-like precursor 0.0229 0.081 0.081
Schistosoma mansoni tyrosine kinase 0.0859 0.316 0.316
Echinococcus multilocularis activin receptor type 0.0019 0.0029 0.0029
Trichomonas vaginalis chromobox protein, putative 0.0034 0.0083 0.0076
Schistosoma mansoni survival motor neuron protein 0.004 0.0107 0.0107
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0032 0.0077 0.0061
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0106 0.0353 0.0353
Onchocerca volvulus 0.0089 0.0289 0.0289
Loa Loa (eye worm) Smad1 0.0047 0.0133 0.0133
Schistosoma mansoni protein kinase 0.0019 0.0029 0.0029
Schistosoma mansoni terminal deoxycytidyl transferase 0.0033 0.0082 0.0082
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0654 0.2396 0.2384
Trypanosoma brucei heat shock protein 90, putative 0.0017 0.002 0.0005
Loa Loa (eye worm) hypothetical protein 0.0229 0.081 0.081
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0022 0.004 0.004
Loa Loa (eye worm) DR-78 0.005 0.0145 0.0145
Loa Loa (eye worm) hypothetical protein 0.0035 0.0087 0.0087
Schistosoma mansoni hypothetical protein 0.0372 0.1344 0.1344
Loa Loa (eye worm) hypothetical protein 0.0106 0.0353 0.0353
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.2695 1 1
Echinococcus granulosus lamin 0.0035 0.009 0.009
Leishmania major protein kinase, putative 0.0019 0.0029 0.0021
Trypanosoma brucei unspecified product 0.0033 0.0082 0.0066
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0034 0.0084 0.0076
Entamoeba histolytica cysteine protease, putative 0.0085 0.0273 0.0253
Loa Loa (eye worm) hypothetical protein 0.0098 0.0324 0.0324
Entamoeba histolytica cysteine proteinase, putative 0.0183 0.0639 0.062
Leishmania major heat shock protein 83-1 0.0017 0.002 0.0013
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0512 0.1864 0.1864
Schistosoma mansoni cathepsin C 0.0085 0.0273 0.0273
Trichomonas vaginalis alpha-glucosidase, putative 0.0017 0.0023 0.0015
Loa Loa (eye worm) hypothetical protein 0.0073 0.0232 0.0232
Echinococcus multilocularis heat shock protein 90 0.0017 0.002 0.002
Brugia malayi PHD-finger family protein 0.0014 0.001 0.001
Brugia malayi Nuclear hormone receptor-like 1 0.0056 0.0167 0.0167
Brugia malayi Nuclear hormone receptor E75 0.005 0.0145 0.0145
Brugia malayi Papain family cysteine protease containing protein 0.0085 0.0273 0.0273
Echinococcus multilocularis cathepsin L 0.0085 0.0273 0.0273
Schistosoma mansoni transcription factor LCR-F1 0.018 0.063 0.063
Echinococcus multilocularis jumonji domain containing 1A 0.0023 0.0045 0.0045
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0327 0.1176 1
Trypanosoma brucei heat shock protein, putative 0.0017 0.002 0.0005
Brugia malayi Importin beta-1 subunit 0.0036 0.0092 0.0092
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0327 0.1176 0.1169
Onchocerca volvulus 0.0035 0.009 0.009
Giardia lamblia Heat shock protein HSP 90-alpha 0.0017 0.002 0.0013
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0183 0.0639 0.0624
Loa Loa (eye worm) heterochromatin protein 1 0.0034 0.0083 0.0083
Loa Loa (eye worm) hypothetical protein 0.0028 0.0062 0.0062
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0089 0.0289 0.0269
Trypanosoma cruzi heat shock protein 85, putative 0.0017 0.002 0.0013
Trypanosoma brucei DNA polymerase kappa, putative 0.0033 0.0082 0.0066
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0327 0.1176 0.1176
Leishmania major heat shock protein 83-1 0.0017 0.002 0.0013
Brugia malayi Cathepsin L-like precursor 0.0327 0.1176 0.1176
Leishmania major heat shock protein 83-1 0.0017 0.002 0.0013
Brugia malayi cathepsin F-like cysteine proteinase 0.0085 0.0273 0.0273
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0019 0.0028 0.002
Leishmania major hypothetical protein, conserved 0.0026 0.0056 0.0048
Giardia lamblia Cathepsin L precursor 0.0085 0.0273 0.0266
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0085 0.0273 0.2256
Brugia malayi Cathepsin L-like precursor 0.0098 0.0324 0.0324
Leishmania major heat shock protein 83-1 0.0017 0.002 0.0013
Mycobacterium ulcerans aldehyde dehydrogenase 0.0029 0.0067 0.0638
Loa Loa (eye worm) hypothetical protein 0.0106 0.0353 0.0353
Trypanosoma cruzi cysteine peptidase, putative 0.0654 0.2396 0.239
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0106 0.0353 0.0353
Trypanosoma cruzi cysteine proteinase, putative 0.0183 0.0639 0.0632
Onchocerca volvulus 0.0085 0.0273 0.0273
Brugia malayi Protein kinase domain containing protein 0.0174 0.0608 0.0608
Giardia lamblia Cathepsin B precursor 0.0383 0.1384 0.1378
Loa Loa (eye worm) RNA binding protein 0.0101 0.0336 0.0336
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0019 0.0028 0.0217
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1049 0.3865 0.3865
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0085 0.0273 0.0266
Schistosoma mansoni flap endonuclease-1 0.0024 0.0046 0.0046
Toxoplasma gondii HEAT repeat-containing protein 0.0036 0.0092 0.0591
Trichomonas vaginalis heat shock protein, putative 0.0013 0.0008 0.0000027188
Brugia malayi Smad1 0.0047 0.0133 0.0133
Brugia malayi jmjC domain containing protein 0.0023 0.0045 0.0045
Giardia lamblia Flap structure-specific endonuclease 0.0026 0.0056 0.0048
Leishmania major cathepsin L-like protease 0.0654 0.2396 0.239
Echinococcus granulosus Smad4 0.0047 0.0133 0.0133
Schistosoma mansoni hypothetical protein 0.0014 0.001 0.001
Echinococcus multilocularis zinc finger protein 0.0034 0.0084 0.0084
Schistosoma mansoni ets-related 0.0106 0.0354 0.0354
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0047 0.0133 0.0133
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0327 0.1176 0.1169
Echinococcus granulosus SAM and MBT domain containing protein 0.0025 0.005 0.005
Schistosoma mansoni hypothetical protein 0.0072 0.0227 0.0227
Echinococcus multilocularis lysine specific demethylase 6a 0.0023 0.0045 0.0045
Plasmodium falciparum serine repeat antigen 1 0.0085 0.0273 0.2256
Trypanosoma brucei cysteine peptidase C (CPC) 0.0383 0.1384 0.137
Echinococcus granulosus cathepsin b 0.1049 0.3865 0.3865
Loa Loa (eye worm) MH2 domain-containing protein 0.0021 0.0036 0.0036
Toxoplasma gondii heat shock protein HSP90 0.0017 0.002 0.0073
Giardia lamblia Cathepsin B precursor 0.0085 0.0273 0.0266
Schistosoma mansoni methyl-cpg binding protein mbd 0.0029 0.0067 0.0067
Toxoplasma gondii preprocathepsin c precursor, putative 0.0085 0.0273 0.1913
Echinococcus multilocularis isocitrate dehydrogenase 0.0034 0.0084 0.0084
Entamoeba histolytica hypothetical protein 0.0029 0.0066 0.0046
Schistosoma mansoni hypothetical protein 0.0083 0.0266 0.0266
Schistosoma mansoni tyrosine kinase 0.0849 0.3122 0.3122
Brugia malayi MH1 domain containing protein 0.0047 0.0133 0.0133
Echinococcus granulosus cathepsin L 0.0085 0.0273 0.0273
Trypanosoma cruzi major cysteine proteinase, putative 0.0085 0.0273 0.0266
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0654 0.2396 0.2384

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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