Detailed information for compound 982642

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 437.28 | Formula: C15H8F9NO2S
  • H donors: 1 H acceptors: 2 LogP: 5.1 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=S(=O)(c1ccc(cc1)C(F)(F)F)Nc1cc(cc(c1)C(F)(F)F)C(F)(F)F
  • InChi: 1S/C15H8F9NO2S/c16-13(17,18)8-1-3-12(4-2-8)28(26,27)25-11-6-9(14(19,20)21)5-10(7-11)15(22,23)24/h1-7,25H
  • InChiKey: XWIMTSBJNRIAGD-UHFFFAOYSA-N  


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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Cyclin, N-terminal domain containing protein 0.0019 0.0007 0.0008
Plasmodium vivax cyclic nucleotide phosphodiesterase, putative 0.0226 0.0257 0.3717
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.1726 0.2063 0.5442
Trichomonas vaginalis cyclin D, putative 0.0019 0.0007 0.0029
Schistosoma mansoni fkbp-rapamycin associated protein 0.0965 0.1147 0.2914
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0226 0.0257 0.1247
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0226 0.0257 0.0653
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0813 0.0964 0.3937
Onchocerca volvulus 0.0019 0.0007 0.0041
Toxoplasma gondii LsmAD domain-containing protein 0.0047 0.0041 0.0198
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0038 0.003 0.003
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0038 0.003 0.0377
Entamoeba histolytica hypothetical protein 0.0329 0.0381 0.1838
Trypanosoma brucei target of rapamycin kinase 3, putative 0.1726 0.2063 0.8427
Onchocerca volvulus 0.0477 0.0559 1
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0813 0.0964 0.3937
Entamoeba histolytica phosphatidylinositol 4-kinase, putative 0.0329 0.0381 0.1838
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0015 0.0002 0.0007
Trichomonas vaginalis conserved hypothetical protein 0.1075 0.1279 0.5225
Brugia malayi aspartic protease BmAsp-2, identical 0.0021 0.0009 0.001
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0015 0.0003 0.0013
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0813 0.0964 0.245
Loa Loa (eye worm) hypothetical protein 0.0019 0.0007 0.0008
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0226 0.0257 0.0257
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0329 0.0381 0.1555
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0329 0.0381 0.1555
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0226 0.0257 0.1049
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.2045 0.2448 1
Loa Loa (eye worm) hypothetical protein 0.0335 0.0387 0.046
Plasmodium vivax glycogen synthase kinase 3, putative 0.0079 0.0079 0.1142
Brugia malayi Calcitonin receptor-like protein seb-1 0.012 0.0128 0.0148
Echinococcus multilocularis phosphatidylinositol 4 phosphate 3 kinase C2 0.0329 0.0381 0.0381
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0021 0.0009 0.0023
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0329 0.0381 0.1555
Echinococcus multilocularis BC026374 protein (S09 family) 0.0017 0.0004 0.0004
Echinococcus multilocularis tumor protein p63 0.0417 0.0486 0.0486
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0226 0.0257 0.0653
Loa Loa (eye worm) hypothetical protein 0.0019 0.0007 0.0009
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0257 0.0293 0.0349
Brugia malayi PHD-finger family protein 0.0032 0.0023 0.0026
Trypanosoma cruzi cyclic nucleotide phosphodiesterase 0.0226 0.0257 0.0653
Loa Loa (eye worm) hypothetical protein 0.0019 0.0007 0.0008
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.7224 0.8687 0.8687
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0037 0.0028 0.0072
Echinococcus multilocularis microtubule associated protein 2 0.1317 0.1571 0.1571
Trichomonas vaginalis PIKK family atypical protein kinase 0.1717 0.2053 0.8386
Loa Loa (eye worm) carboxylesterase 0.0017 0.0004 0.0005
Echinococcus granulosus cyclins 0.0019 0.0007 0.0007
Echinococcus granulosus cyclins 0.0019 0.0007 0.0007
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.1099 0.1308 0.3325
Plasmodium vivax hypothetical protein 0.0329 0.0381 0.5507
Loa Loa (eye worm) RNA binding protein 0.0148 0.0162 0.0193
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.1711 0.2045 0.8354
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.0037 0.0095
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0019 0.0007 0.0037
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0329 0.0381 0.0438
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0021 0.0009 0.0023
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0329 0.0381 0.1555
Onchocerca volvulus 0.0079 0.0079 0.1347
Loa Loa (eye worm) phosphatidylinositol 3 0.0329 0.0381 0.0452
Echinococcus granulosus phosphatidylinositol 4 kinase beta 0.0329 0.0381 0.0381
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0813 0.0964 0.3937
Schistosoma mansoni acetylcholinesterase 0.0017 0.0004 0.0011
Toxoplasma gondii hypothetical protein 0.0014 0.0001 0.0007
Brugia malayi hypothetical protein 0.0021 0.0009 0.001
Trichomonas vaginalis conserved hypothetical protein 0.0587 0.0691 0.2823
Trypanosoma cruzi PAB1-binding protein , putative 0.0047 0.0041 0.0104
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0226 0.0257 0.1049
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0226 0.0257 0.3717
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.1428 0.1705 0.4333
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0025 0.0014 0.0017
Trypanosoma cruzi fatty acid desaturase, putative 0.0063 0.006 0.0152
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0226 0.0257 0.1247
Brugia malayi Protein kinase domain containing protein 0.0279 0.032 0.0368
Echinococcus multilocularis high affinity cAMP specific 3',5' cyclic 0.0226 0.0257 0.0257
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0021 0.001 0.001
Trypanosoma cruzi hypothetical protein, conserved 0.0226 0.0257 0.0653
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0329 0.0381 0.0967
Plasmodium vivax plasmepsin IV, putative 0.0021 0.0009 0.0132
Trichomonas vaginalis PIKK family atypical protein kinase 0.1428 0.1705 0.6964
Onchocerca volvulus 0.0292 0.0336 0.5983
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0059 0.0055 0.0139
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0329 0.0381 0.0381
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0813 0.0964 0.3937
Echinococcus multilocularis serine protein kinase ATM 0.1428 0.1705 0.1705
Entamoeba histolytica acyl-CoA synthetase, putative 0.0025 0.0014 0.007
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0813 0.0964 0.3937
Trichomonas vaginalis cyclin A, putative 0.0019 0.0007 0.0029
Plasmodium vivax phosphatidylinositol 3- and 4-kinase, putative 0.0329 0.0381 0.5507
Echinococcus multilocularis geminin 0.0079 0.0079 0.0079
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0329 0.0381 0.1847
Trypanosoma cruzi CYC2-like cyclin, putative 0.0019 0.0007 0.0018
Leishmania major DNA polymerase eta, putative 0.0015 0.0003 0.0007
Echinococcus multilocularis PIK kinase, FAT and Armadillo domain containing protein 0.0746 0.0883 0.0883
Leishmania major cAMP phosphodiesterase A, putative;with=GeneDB:LinJ18_V3.1100 0.0226 0.0257 0.0678
Trichomonas vaginalis PIKK family atypical protein kinase 0.1732 0.2071 0.8459
Echinococcus multilocularis Zinc finger, PHD finger 0.0329 0.0381 0.0381
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.1428 0.1705 0.6964
Brugia malayi ImpB/MucB/SamB family protein 0.0022 0.001 0.0012
Loa Loa (eye worm) aspartic protease BmAsp-1 0.0021 0.0009 0.0011
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0892 0.1059 0.1059
Trichomonas vaginalis PIKK family atypical protein kinase 0.1726 0.2063 0.8426
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.1732 0.2071 0.8459
Loa Loa (eye worm) hypothetical protein 0.0053 0.0048 0.0057
Loa Loa (eye worm) hypothetical protein 0.0017 0.0004 0.0005
Echinococcus granulosus cyclin b3 0.0019 0.0007 0.0007
Mycobacterium ulcerans two component sensor histidine kinase DevS 0.0587 0.0691 1
Toxoplasma gondii aspartyl protease ASP3 0.0021 0.0009 0.0044
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0813 0.0964 0.3937
Toxoplasma gondii hypothetical protein 0.0587 0.0691 0.3353
Loa Loa (eye worm) hypothetical protein 0.0022 0.001 0.0012
Giardia lamblia Hypothetical protein 0.0226 0.0257 0.1241
Trypanosoma brucei fatty acid desaturase, putative 0.0063 0.006 0.0244
Echinococcus granulosus tar DNA binding protein 0.0148 0.0162 0.0162
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0813 0.0964 0.3937
Brugia malayi hypothetical protein 0.0047 0.0041 0.0047
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0059 0.0055 0.0055
Leishmania major phosphatidylinositol 3-related kinase, putative 0.2045 0.2448 0.6459
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0329 0.0381 0.5507
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0226 0.0257 0.1247
Plasmodium vivax plasmepsin V, putative 0.0021 0.0009 0.0132
Entamoeba histolytica cell division protein kinase 2, putative 0.0025 0.0014 0.0069
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0793 0.0939 0.2387
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.3279 0.3934 1
Giardia lamblia Kinase, CMGC GSK 0.0079 0.0079 0.0381
Trichomonas vaginalis cyclin B, putative 0.0019 0.0007 0.0029
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0329 0.0381 0.0967
Mycobacterium ulcerans putative regulatory protein 0.0587 0.0691 1
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0192 0.0215 0.0256
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0038 0.003 0.0377
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0226 0.0257 0.0257
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0226 0.0257 0.1247
Trichomonas vaginalis conserved hypothetical protein 0.0226 0.0257 0.1049
Schistosoma mansoni lamin 0.0019 0.0007 0.0017
Brugia malayi plexin A 0.0023 0.0012 0.0013
Trypanosoma brucei ISWI complex protein 0.002 0.0008 0.0031
Echinococcus granulosus histone lysine methyltransferase setb 0.0059 0.0055 0.0055
Echinococcus multilocularis snurportin 1 0.0192 0.0215 0.0215
Loa Loa (eye worm) hypothetical protein 0.0226 0.0257 0.0305
Mycobacterium leprae conserved hypothetical protein 0.0329 0.0381 0.5413
Loa Loa (eye worm) acyl-CoA desaturase 0.0063 0.006 0.0071
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0014 0.0017
Trypanosoma brucei mitotic cyclin 6 0.0019 0.0007 0.0029
Trypanosoma cruzi ISWI complex protein 0.002 0.0008 0.002
Brugia malayi Bromodomain containing protein 0.0096 0.01 0.0115
Echinococcus multilocularis GPCR, family 2 0.0038 0.003 0.003
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0279 0.032 0.0368
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0226 0.0257 0.0296
Trypanosoma cruzi cyclin, putative 0.0019 0.0007 0.0018
Echinococcus multilocularis cyclin dependent kinase 0.0025 0.0014 0.0014
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0329 0.0381 0.1838
Schistosoma mansoni phosphatidylinositol 3-kinase class 0.0329 0.0381 0.0967
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0226 0.0257 0.3717
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0025 0.0014 0.0149
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0226 0.0257 0.0257
Leishmania major hypothetical protein, conserved 0.0226 0.0257 0.0678
Trypanosoma brucei cdc2-related kinase 3 0.0025 0.0014 0.0058
Onchocerca volvulus 0.0063 0.006 0.0999
Loa Loa (eye worm) TAR-binding protein 0.0148 0.0162 0.0193
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0021 0.0009 0.0023
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0017 0.0004 0.0011
Echinococcus granulosus serine:threonine protein kinase SMG1 0.0965 0.1147 0.1147
Trichomonas vaginalis PIKK family atypical protein kinase 0.1711 0.2045 0.8354
Schistosoma mansoni zinc finger protein 0.0025 0.0014 0.0036
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.3279 0.3934 0.4529
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0813 0.0964 0.3937
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0813 0.0964 0.3937
Loa Loa (eye worm) carboxylesterase 0.0099 0.0103 0.0123
Plasmodium falciparum plasmepsin I 0.0021 0.0009 0.0132
Trypanosoma cruzi DNA polymerase eta, putative 0.0015 0.0003 0.0007
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0079 0.0079 0.0094
Trichomonas vaginalis cyclin B, putative 0.0019 0.0007 0.0029
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0022 0.001 0.001
Trichomonas vaginalis PIKK family atypical protein kinase 0.1724 0.2061 0.8418
Trichomonas vaginalis cyclins, putative 0.0019 0.0007 0.0029
Loa Loa (eye worm) phosphatidylinositol kinase 0.0329 0.0381 0.0452
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0226 0.0257 0.3717
Leishmania major phosphatidylinositol 4-kinase alpha, putative 0.0329 0.0381 0.1004
Echinococcus granulosus snurportin 1 0.0192 0.0215 0.0215
Trypanosoma cruzi fatty acid desaturase, putative 0.0063 0.006 0.0152
Trichomonas vaginalis PIKK family atypical protein kinase 0.0965 0.1147 0.4683
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0226 0.0257 0.1049
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.0014 0.0149
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.1428 0.1705 0.4333
Trypanosoma cruzi PAB1-binding protein , putative 0.0047 0.0041 0.0104
Echinococcus granulosus protein kinase shaggy 0.0079 0.0079 0.0079
Echinococcus granulosus para nitrobenzyl esterase 0.0017 0.0004 0.0004
Trypanosoma cruzi cyclin, putative 0.0019 0.0007 0.0018
Trichomonas vaginalis cyclin B3, putative 0.0019 0.0007 0.0029
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0021 0.0009 0.0023
Schistosoma mansoni importin beta-1 0.0018 0.0006 0.0015
Giardia lamblia G2/mitotic-specific cyclin B 0.0019 0.0007 0.0034
Plasmodium falciparum glycogen synthase kinase 3 0.0079 0.0079 0.1142
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0021 0.0009 0.0023
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0813 0.0964 0.3937
Toxoplasma gondii target of rapamycin (TOR), putative 0.1724 0.2061 1
Brugia malayi Eukaryotic aspartyl protease family protein 0.0021 0.0009 0.001
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0038 0.003 0.0146
Trichomonas vaginalis PIKK family atypical protein kinase 0.1726 0.2063 0.8426
Trichomonas vaginalis PIKK family atypical protein kinase 0.1724 0.2061 0.8418
Echinococcus granulosus cyclins 0.0019 0.0007 0.0007
Echinococcus multilocularis high affinity cgmp specific 3' 5' cyclic 0.0226 0.0257 0.0257
Loa Loa (eye worm) latrophilin receptor protein 2 0.0038 0.003 0.0035
Plasmodium vivax phosphatidylinositol 3-kinase, putative 0.0329 0.0381 0.5507
Schistosoma mansoni cathepsin D (A01 family) 0.0021 0.0009 0.0023
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0017 0.0004 0.0011
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0038 0.003 0.003
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit gamma, putative 0.0329 0.0381 0.1555
Leishmania major phosphatidylinositol 4-kinase, putative 0.0329 0.0381 0.1004
Loa Loa (eye worm) hypothetical protein 0.0053 0.0048 0.0057
Trichomonas vaginalis PIKK family atypical protein kinase 0.1732 0.2071 0.8459
Brugia malayi Cyclin, N-terminal domain containing protein 0.0131 0.0142 0.0164
Brugia malayi cell division control protein 2 homolog 0.0025 0.0014 0.0016
Schistosoma mansoni serine/threonine protein kinase 0.0025 0.0014 0.0036
Loa Loa (eye worm) hypothetical protein 0.0017 0.0004 0.0005
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0329 0.0381 0.0438
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0079 0.0079 0.0201
Entamoeba histolytica protein kinase domain containing protein 0.0079 0.0079 0.0381
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0019 0.0007 0.0008
Brugia malayi intracellular kinase 0.0079 0.0079 0.0091
Schistosoma mansoni gliotactin 0.0017 0.0004 0.0011
Onchocerca volvulus Huntingtin homolog 0.0059 0.0055 0.0908
Leishmania major hypothetical protein, conserved 0.316 0.3791 1
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0226 0.0257 0.1049
Schistosoma mansoni hypothetical protein 0.0329 0.0381 0.0967
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0226 0.0257 0.1247
Echinococcus multilocularis cyclins 0.0019 0.0007 0.0007
Loa Loa (eye worm) aspartic protease BmAsp-2 0.0021 0.0009 0.0011
Loa Loa (eye worm) hypothetical protein 0.0226 0.0257 0.0305
Brugia malayi hypothetical protein 0.0053 0.0048 0.0055
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0079 0.0079 0.0094
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0226 0.0257 0.0653
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0015 0.0002 0.0007
Trypanosoma brucei phosphatidylinositol 3-kinase catalytic subunit, putative 0.0329 0.0381 0.1555
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0226 0.0257 0.0257
Plasmodium vivax importin-beta 2, putative 0.0018 0.0006 0.0083
Echinococcus granulosus importin subunit beta 1 0.0018 0.0006 0.0006
Echinococcus granulosus phosphatidylinositol 45 bisphosphate 3 kinase 0.0329 0.0381 0.0381
Echinococcus multilocularis acetylcholinesterase 0.0099 0.0103 0.0103
Loa Loa (eye worm) hypothetical protein 0.0017 0.0004 0.0005
Brugia malayi Bromodomain containing protein 0.0049 0.0043 0.005
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0226 0.0257 0.1049
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0029 0.0019 0.0048
Echinococcus granulosus GPCR family 2 0.0038 0.003 0.003
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0813 0.0964 0.3937
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0038 0.003 0.0436
Plasmodium falciparum importin beta, putative 0.0018 0.0006 0.0083
Trichomonas vaginalis PIKK family atypical protein kinase 0.0336 0.0389 0.1587
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.1732 0.2071 0.8459
Loa Loa (eye worm) hypothetical protein 0.0335 0.0387 0.046
Loa Loa (eye worm) hypothetical protein 0.0025 0.0014 0.0017
Trichomonas vaginalis PIKK family atypical protein kinase 0.0329 0.0381 0.1555
Trypanosoma brucei importin beta-1 subunit, putative 0.0018 0.0006 0.0023
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0329 0.0381 0.1555
Brugia malayi RNA binding protein 0.0148 0.0162 0.0187
Leishmania major importin beta-1 subunit, putative 0.0015 0.0002 0.0004
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.0037 0.0095
Loa Loa (eye worm) phosphatidylinositol 3 0.0329 0.0381 0.0452
Mycobacterium leprae conserved hypothetical protein 0.0587 0.0691 1
Loa Loa (eye worm) hypothetical protein 0.0023 0.0012 0.0014
Loa Loa (eye worm) intermediate filament protein 0.0019 0.0007 0.0008
Trichomonas vaginalis cyclin D, putative 0.0019 0.0007 0.0029
Echinococcus granulosus plexin a4 0.0023 0.0012 0.0012
Trichomonas vaginalis PIKK family atypical protein kinase 0.1726 0.2063 0.8426
Brugia malayi Pepsin A precursor 0.0021 0.0009 0.001
Echinococcus multilocularis cyclin dependent kinase 5 0.0025 0.0014 0.0014
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0006 0.0019
Leishmania major stearic acid desaturase, putative 0.0063 0.006 0.0157
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0226 0.0257 0.1247
Loa Loa (eye worm) hypothetical protein 0.012 0.0128 0.0153
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0044 0.0037 0.0037
Trichomonas vaginalis PIKK family atypical protein kinase 0.2045 0.2448 1
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0025 0.0014 0.0149
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0813 0.0964 0.3937
Trypanosoma cruzi hypothetical protein, conserved 0.0226 0.0257 0.0653
Echinococcus multilocularis dna polymerase eta 0.0022 0.001 0.001
Echinococcus multilocularis lamin 0.0019 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0226 0.0257 0.0305
Echinococcus multilocularis carboxylesterase 5A 0.0099 0.0103 0.0103
Plasmodium falciparum ataxin-2 like protein, putative 0.0047 0.0041 0.0591
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0329 0.0381 0.0438
Loa Loa (eye worm) aspartyl protease 6 0.0021 0.0009 0.0011
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0226 0.0257 0.0257
Echinococcus multilocularis DNA dependent protein kinase catalytic subunit 0.8313 1 1
Echinococcus multilocularis phosphatidylinositol 4 kinase alpha 0.0329 0.0381 0.0381
Giardia lamblia Kinase, CMGC CDK 0.0025 0.0014 0.0069
Loa Loa (eye worm) transcription factor SMAD2 0.0186 0.0208 0.0247
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0329 0.0381 0.1555
Schistosoma mansoni tar DNA-binding protein 0.0148 0.0162 0.0412
Onchocerca volvulus 0.0063 0.006 0.0999
Echinococcus multilocularis neuroligin 0.0017 0.0004 0.0004
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0813 0.0964 0.245
Brugia malayi latrophilin 2 splice variant baaae 0.0082 0.0083 0.0095
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.3279 0.3934 0.3934
Onchocerca volvulus 0.0021 0.0009 0.0088
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0329 0.0381 0.0967
Echinococcus multilocularis 0.0329 0.0381 0.0381
Trichomonas vaginalis conserved hypothetical protein 0.0636 0.075 0.3063
Brugia malayi Probable ClpP-like protease 0.0038 0.003 0.0035
Loa Loa (eye worm) calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase 0.0226 0.0257 0.0305
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0025 0.0014 0.0069
Schistosoma mansoni bromodomain containing protein 0.0081 0.0082 0.0208
Entamoeba histolytica acyl-coA synthetase, putative 0.0025 0.0014 0.007
Schistosoma mansoni hypothetical protein 0.0078 0.0078 0.0199
Onchocerca volvulus 0.0019 0.0007 0.0041
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0226 0.0257 0.0257
Trypanosoma cruzi cAMP-specific phosphodiesterase, putative 0.0226 0.0257 0.0653
Trichomonas vaginalis conserved hypothetical protein 0.0746 0.0883 0.3606
Echinococcus granulosus cyclin dependent kinase 0.0025 0.0014 0.0014
Loa Loa (eye worm) phosphatidylinositol 4-kinase type 3 alpha isoform 1 0.0329 0.0381 0.0452
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0044 0.0037 0.0043
Trichomonas vaginalis PIKK family atypical protein kinase 0.1717 0.2053 0.8386
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0329 0.0381 0.0967
Echinococcus granulosus lamin 0.0019 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0813 0.0964 0.1146
Schistosoma mansoni hypothetical protein 0.0038 0.003 0.0076
Loa Loa (eye worm) hypothetical protein 0.0477 0.0559 0.0664
Loa Loa (eye worm) hypothetical protein 0.0099 0.0103 0.0123
Loa Loa (eye worm) hypothetical protein 0.6997 0.8414 1
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0813 0.0964 0.3937
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.1732 0.2071 0.5463
Brugia malayi RNA recognition motif domain containing protein 0.0148 0.0162 0.0187
Loa Loa (eye worm) hypothetical protein 0.0055 0.005 0.0059
Leishmania major phosphatidylinositol kinase, putative 0.0329 0.0381 0.1004
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0813 0.0964 0.3937
Brugia malayi Cyclin, N-terminal domain containing protein 0.0019 0.0007 0.0008
Echinococcus multilocularis zinc finger protein 0.0025 0.0014 0.0014
Plasmodium falciparum stearoyl-CoA desaturase 0.0063 0.006 0.0863
Schistosoma mansoni cyclin B3 0.0019 0.0007 0.0018
Giardia lamblia Kinase, CMGC GSK 0.0079 0.0079 0.0381
Trypanosoma brucei cAMP-specific phosphodiesterase, putative 0.0226 0.0257 0.1049
Entamoeba histolytica hypothetical protein 0.0015 0.0002 0.0008
Trichomonas vaginalis CMGC family protein kinase 0.0025 0.0014 0.0058
Trypanosoma cruzi DNA polymerase eta, putative 0.0022 0.001 0.0027
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0006 0.0019
Trichomonas vaginalis PIKK family atypical protein kinase 0.1724 0.2061 0.8418
Loa Loa (eye worm) cyclin domain-containing protein 0.0019 0.0007 0.0008
Plasmodium falciparum plasmepsin III 0.0021 0.0009 0.0132
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0329 0.0381 0.0381
Trichomonas vaginalis calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0226 0.0257 0.1049
Giardia lamblia Phosphoinositide-3-kinase, catalytic, alpha polypeptide 0.0329 0.0381 0.1838
Trypanosoma cruzi target of rapamycin kinase 3 0.1726 0.2063 0.5244
Onchocerca volvulus 0.0037 0.0028 0.0436
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0226 0.0257 0.1049
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.1082 0.1287 0.5258
Trichomonas vaginalis PIKK family atypical protein kinase 0.1717 0.2053 0.8386
Echinococcus multilocularis cyclins 0.0019 0.0007 0.0007
Echinococcus multilocularis cyclins 0.0019 0.0007 0.0007
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.1732 0.2071 0.2071
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0813 0.0964 0.3937
Echinococcus multilocularis cyclin dependent kinase 1 0.0025 0.0014 0.0014
Brugia malayi Carboxylesterase family protein 0.0099 0.0103 0.0119
Brugia malayi Carboxylesterase family protein 0.0017 0.0004 0.0005
Loa Loa (eye worm) hypothetical protein 0.0082 0.0083 0.0098
Plasmodium falciparum phosphodiesterase gamma, putative 0.0226 0.0257 0.3717
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0078 0.0078 0.0078
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0329 0.0381 0.1847
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0279 0.032 0.038
Entamoeba histolytica hypothetical protein 0.0329 0.0381 0.1838
Echinococcus granulosus cyclin dependent kinase 5 0.0025 0.0014 0.0014
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0226 0.0257 0.0257
Echinococcus multilocularis para nitrobenzyl esterase 0.0017 0.0004 0.0004
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0079 0.0079 0.0383
Echinococcus granulosus zinc finger protein 0.0025 0.0014 0.0014
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0025 0.0014 0.0003
Trypanosoma brucei phosphatidylinositol 4-kinase alpha, putative 0.0329 0.0381 0.1555
Trypanosoma cruzi ISWI complex protein 0.002 0.0008 0.002
Toxoplasma gondii hypothetical protein 0.0587 0.0691 0.3353
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0025 0.0014 0.0017
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0007 0.0029
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0077 0.0076 0.0076
Giardia lamblia Hypothetical protein 0.0019 0.0007 0.0034
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0038 0.003 0.5
Toxoplasma gondii aspartyl protease 0.0021 0.0009 0.0044
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0226 0.0257 0.0653
Toxoplasma gondii HEAT repeat-containing protein 0.0018 0.0006 0.0028
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0329 0.0381 0.0381
Leishmania major CYC2-like cyclin, putative,cyclin 6, putative 0.0019 0.0007 0.0018
Entamoeba histolytica cyclin, putative 0.0019 0.0007 0.0034
Brugia malayi Protein kinase domain containing protein 0.0025 0.0014 0.0016
Toxoplasma gondii FATC domain-containing protein 0.1428 0.1705 0.8272
Brugia malayi TAR-binding protein 0.0148 0.0162 0.0187
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0025 0.0014 0.0146
Plasmodium vivax aspartyl protease, putative 0.0021 0.0009 0.0132
Schistosoma mansoni methyl-cpg binding protein mbd 0.0022 0.001 0.0026
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.3279 0.3934 1
Trypanosoma cruzi hypothetical protein, conserved 0.0226 0.0257 0.0653
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0813 0.0964 0.3937
Schistosoma mansoni thyroid hormone receptor 0.0091 0.0094 0.0238
Trichomonas vaginalis CMGC family protein kinase 0.0025 0.0014 0.0058
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0813 0.0964 0.3937
Toxoplasma gondii eukaryotic aspartyl protease superfamily protein 0.0021 0.0009 0.0044
Mycobacterium tuberculosis Conserved hypothetical protein 0.0329 0.0381 0.548
Brugia malayi Plexin repeat family protein 0.0019 0.0007 0.0008
Trypanosoma cruzi hypothetical protein, conserved 0.0226 0.0257 0.0653
Plasmodium vivax ataxin-2 like protein, putative 0.0047 0.0041 0.0591
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0279 0.032 0.038
Plasmodium vivax hypothetical protein, conserved 0.0329 0.0381 0.5507
Trypanosoma cruzi fatty acid desaturase, putative 0.0063 0.006 0.0152
Schistosoma mansoni hypothetical protein 0.0038 0.003 0.0076
Loa Loa (eye worm) hypothetical protein 0.0047 0.0041 0.0049
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0019 0.0007 0.0037
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.1732 0.2071 1
Trypanosoma cruzi cdc2-related kinase 1 0.0025 0.0014 0.0036
Trichomonas vaginalis PIKK family atypical protein kinase 0.0978 0.1162 0.4748
Schistosoma mansoni calcium/calmodulin-dependent 35-cyclic nucleotide phosphodiesterase 0.0226 0.0257 0.0653
Echinococcus granulosus cyclins 0.0019 0.0007 0.0007
Schistosoma mansoni methyl-cpg binding protein mbd 0.0022 0.001 0.0026
Schistosoma mansoni BC026374 protein (S09 family) 0.0017 0.0004 0.0011
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0226 0.0257 0.3717
Leishmania major hypothetical protein, conserved 0.0226 0.0257 0.0678
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0038 0.003 0.5
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0329 0.0381 0.0967
Trichomonas vaginalis CMGC family protein kinase 0.0079 0.0079 0.0322
Trichomonas vaginalis spcc417.12 protein, putative 0.0017 0.0004 0.0017
Leishmania major fatty-acid desaturase, putative 0.0063 0.006 0.0157
Loa Loa (eye worm) hypothetical protein 0.0059 0.0055 0.0065
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0226 0.0257 0.1247
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0046 0.004 0.004
Loa Loa (eye worm) hypothetical protein 0.0038 0.003 0.0036
Schistosoma mansoni phosphatidylinositol 4-kinase type-II 0.0329 0.0381 0.0967
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0226 0.0257 0.1247
Echinococcus multilocularis musashi 0.0019 0.0007 0.0007
Brugia malayi Carboxylesterase family protein 0.0017 0.0004 0.0005
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0226 0.0257 0.1247
Loa Loa (eye worm) hypothetical protein 0.0025 0.0014 0.0017
Giardia lamblia Phosphatidylinositol 4-kinase 0.0329 0.0381 0.1838
Entamoeba histolytica protein kinase, putative 0.0079 0.0079 0.0381
Schistosoma mansoni memapsin-2 (A01 family) 0.0518 0.0608 0.1544
Echinococcus multilocularis cyclins 0.0019 0.0007 0.0007
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0021 0.001 0.001
Entamoeba histolytica protein kinase rad3, putative 0.0965 0.1147 0.5536
Mycobacterium tuberculosis Two component sensor histidine kinase DosT 0.0587 0.0691 1
Loa Loa (eye worm) hypothetical protein 0.0017 0.0004 0.0005
Plasmodium falciparum plasmepsin VI 0.0021 0.0009 0.0132
Brugia malayi Probable 3',5'-cyclic phosphodiesterase T04D3.3, putative 0.0226 0.0257 0.0296
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0279 0.032 0.5689
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0813 0.0964 0.3937
Echinococcus multilocularis cyclin B3 1 0.0019 0.0007 0.0007
Loa Loa (eye worm) bromodomain containing protein 0.0023 0.0011 0.0014
Brugia malayi RNA, U transporter 1 0.0051 0.0046 0.0052
Trichomonas vaginalis PIKK family atypical protein kinase 0.1724 0.2061 0.8418
Entamoeba histolytica hypothetical protein 0.0329 0.0381 0.1838
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0017 0.0004 0.0017
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.0813 0.0964 0.0964
Trichomonas vaginalis cyclins, putative 0.0019 0.0007 0.0029
Trichomonas vaginalis PIKK family atypical protein kinase 0.1726 0.2063 0.8426
Plasmodium vivax aspartyl protease, putative 0.0021 0.0009 0.0132
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.1732 0.2071 0.5463
Brugia malayi acyl-CoA desaturase 0.0063 0.006 0.0069
Trypanosoma brucei DNA polymerase eta, putative 0.0022 0.001 0.0043
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.0813 0.0964 0.245
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0813 0.0964 0.111
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0329 0.0381 0.0967
Echinococcus multilocularis acetylcholinesterase 0.0099 0.0103 0.0103
Loa Loa (eye worm) hypothetical protein 0.0329 0.0381 0.0452
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0329 0.0381 0.1555
Leishmania major hypothetical protein, conserved 0.0047 0.0041 0.0108
Schistosoma mansoni cathepsin D (A01 family) 0.0021 0.0009 0.0023
Loa Loa (eye worm) hypothetical protein 0.0017 0.0004 0.0005
Mycobacterium ulcerans hypothetical protein 0.0025 0.0014 0.0149
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0965 0.1147 0.132
Echinococcus granulosus cyclin B 0.0019 0.0007 0.0007
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0025 0.0014 0.0149
Plasmodium falciparum phosphodiesterase delta, putative 0.0226 0.0257 0.3717
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0078 0.0078 0.0078
Entamoeba histolytica phosphatidylinositol 3-kinase 3, putative 0.0329 0.0381 0.1838
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0014 0.0038
Entamoeba histolytica cyclin family protein 0.0019 0.0007 0.0034
Schistosoma mansoni lozenge 0.006 0.0056 0.0143
Echinococcus granulosus phosphatidylinositol 4 phosphate 3 kinase C2 0.0329 0.0381 0.0381
Echinococcus granulosus methyl CpG binding domain protein 2 0.0022 0.001 0.001
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0226 0.0257 0.1049
Brugia malayi hypothetical protein 0.003 0.0021 0.0024
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0021 0.0009 0.0023
Plasmodium falciparum plasmepsin IV 0.0021 0.0009 0.0132
Trichomonas vaginalis PIKK family atypical protein kinase 0.1724 0.2061 0.8418
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0038 0.003 0.0234
Schistosoma mansoni cyclin B 0.0019 0.0007 0.0018
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0329 0.0381 0.1555
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.1299 0.155 0.7483
Trichomonas vaginalis importin beta-1, putative 0.0015 0.0002 0.0007
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0037 0.0028 0.0028
Loa Loa (eye worm) hypothetical protein 0.0329 0.0381 0.0452
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0226 0.0257 0.1247
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0025 0.0014 0.0149
Giardia lamblia Cyclin A 0.0019 0.0007 0.0034
Loa Loa (eye worm) hypothetical protein 0.0019 0.0007 0.0008
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0226 0.0257 0.1247
Plasmodium falciparum acyl-CoA synthetase 0.0019 0.0007 0.0098
Trichomonas vaginalis cyclin B, putative 0.0019 0.0007 0.0029
Loa Loa (eye worm) pigment dispersing factor receptor c 0.012 0.0128 0.0153
Entamoeba histolytica acyl-CoA synthetase, putative 0.0025 0.0014 0.007
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0813 0.0964 0.3937
Schistosoma mansoni neuroligin 3 (S09 family) 0.0017 0.0004 0.0011
Trypanosoma brucei hypothetical protein, conserved 0.0226 0.0257 0.1049
Loa Loa (eye worm) cyclin domain-containing protein 0.0131 0.0142 0.0169
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.0014 0.0149
Entamoeba histolytica protein kinase domain containing protein 0.0079 0.0079 0.0381
Brugia malayi Importin beta-1 subunit 0.0018 0.0006 0.0007
Loa Loa (eye worm) hypothetical protein 0.0061 0.0058 0.0068
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.0965 0.1147 0.1147
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0014 0.0038
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0329 0.0381 0.1838
Schistosoma mansoni serine/threonine protein kinase 0.0279 0.032 0.0813
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0279 0.032 0.032
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0226 0.0257 0.3717
Trichomonas vaginalis PIKK family atypical protein kinase 0.1711 0.2045 0.8354
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0044 0.0037 0.0037
Trichomonas vaginalis PIKK family atypical protein kinase 0.1726 0.2063 0.8426
Plasmodium vivax SET domain protein, putative 0.0037 0.0028 0.0412
Schistosoma mansoni DNA polymerase eta 0.0022 0.001 0.0027
Schistosoma mansoni tar DNA-binding protein 0.0148 0.0162 0.0412
Entamoeba histolytica cyclin, putative 0.0019 0.0007 0.0034
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0226 0.0257 0.3717
Trichomonas vaginalis cyclins, putative 0.0019 0.0007 0.0029
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0017 0.0004 0.0004
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0014 0.0017
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.0037 0.0095
Plasmodium falciparum plasmepsin X 0.0021 0.0009 0.0132
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0226 0.0257 0.0653
Plasmodium vivax phosphodiesterase gamma, putative 0.0226 0.0257 0.3717
Trichomonas vaginalis PIKK family atypical protein kinase 0.0978 0.1162 0.4748
Echinococcus granulosus lamin dm0 0.0019 0.0007 0.0007
Loa Loa (eye worm) MH2 domain-containing protein 0.0186 0.0208 0.0247
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0025 0.0014 0.0149
Onchocerca volvulus 0.0019 0.0007 0.0055
Echinococcus granulosus BC026374 protein S09 family 0.0017 0.0004 0.0004
Schistosoma mansoni camp-specific cyclic nucleotide phosphodiesterase 0.0226 0.0257 0.0653
Trypanosoma cruzi cdc2-related kinase 3 0.0025 0.0014 0.0036
Brugia malayi hypothetical protein 0.0017 0.0004 0.0005
Brugia malayi Carboxylesterase family protein 0.0099 0.0103 0.0119
Echinococcus granulosus dna polymerase eta 0.0022 0.001 0.001
Echinococcus multilocularis lamin dm0 0.0019 0.0007 0.0007
Schistosoma mansoni tar DNA-binding protein 0.0148 0.0162 0.0412
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.0021 0.0009 0.0009
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0038 0.003 0.0034
Loa Loa (eye worm) hypothetical protein 0.641 0.7707 0.916
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0025 0.0014 0.0146
Trichomonas vaginalis PIKK family atypical protein kinase 0.1717 0.2053 0.8386
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0813 0.0964 0.3937
Brugia malayi MH2 domain containing protein 0.0186 0.0208 0.0239
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0025 0.0014 0.0014
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0025 0.0014 0.0149
Schistosoma mansoni zinc finger protein 0.002 0.0008 0.002
Trypanosoma cruzi phosphatidylinositol 3-kinase vps34-like 0.0329 0.0381 0.0967
Trichomonas vaginalis PIKK family atypical protein kinase 0.0636 0.075 0.3063
Loa Loa (eye worm) hypothetical protein 0.0017 0.0004 0.0005
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0038 0.003 0.003
Loa Loa (eye worm) hypothetical protein 0.0965 0.1147 0.1363
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0329 0.0381 0.1555
Schistosoma mansoni lamin 0.0019 0.0007 0.0017
Trypanosoma cruzi importin beta-1 subunit, putative 0.0015 0.0002 0.0004
Echinococcus granulosus phosphatidylinositol 3 kinase catalytic subunit 0.0329 0.0381 0.0381
Trichomonas vaginalis PIKK family atypical protein kinase 0.1711 0.2045 0.8354
Loa Loa (eye worm) hypothetical protein 0.0091 0.0093 0.0111
Plasmodium vivax aspartyl proteinase, putative 0.0021 0.0009 0.0132
Trichomonas vaginalis PIKK family atypical protein kinase 0.1299 0.155 0.6329
Plasmodium falciparum phosphatidylinositol 3-kinase 0.0329 0.0381 0.5507
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0329 0.0381 0.0967
Loa Loa (eye worm) PHD-finger family protein 0.0026 0.0016 0.0019
Leishmania major phosphatidylinositol 3-kinase, putative 0.0329 0.0381 0.1004
Brugia malayi FAT domain containing protein 0.0746 0.0883 0.1016
Echinococcus granulosus peptidase Clp S14 family 0.0025 0.0014 0.0014
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0017 0.0004 0.0004
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0079 0.0079 0.0079
Echinococcus granulosus high affinity cgmp specific 3' 5' cyclic 0.0226 0.0257 0.0257
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0025 0.0014 0.0003
Loa Loa (eye worm) hypothetical protein 0.0018 0.0006 0.0007
Schistosoma mansoni peptidase Clp (S14 family) 0.0038 0.003 0.0077
Echinococcus multilocularis G2:mitotic specific cyclin B3 0.0019 0.0007 0.0007
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0226 0.0257 0.0653
Schistosoma mansoni intermediate filament proteins 0.0019 0.0007 0.0017
Brugia malayi intermediate filament protein 0.0019 0.0007 0.0008
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.012 0.0128 0.0148
Onchocerca volvulus 0.0021 0.0009 0.0088
Brugia malayi Carboxylesterase family protein 0.0017 0.0004 0.0005
Entamoeba histolytica phosphatidylinositol-4,5-bisphosphate 3-kinase, putative 0.0329 0.0381 0.1838
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0813 0.0964 0.3937
Echinococcus granulosus geminin 0.0079 0.0079 0.0079
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0226 0.0257 0.0257
Trichomonas vaginalis cyclin B, putative 0.0019 0.0007 0.0029
Brugia malayi Pre-SET motif family protein 0.0257 0.0293 0.0338
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0079 0.0079 0.0201
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0329 0.0381 0.1838
Toxoplasma gondii hypothetical protein 0.0587 0.0691 0.3353
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0226 0.0257 0.1049
Loa Loa (eye worm) hypothetical protein 0.0099 0.0103 0.0123
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0226 0.0257 0.1049
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0148 0.0162 0.0193
Loa Loa (eye worm) hypothetical protein 0.0021 0.0009 0.0011
Echinococcus multilocularis phosphatidylinositol 4,5 bisphosphate 3 kinase 0.0329 0.0381 0.0381
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0279 0.032 0.032
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0038 0.003 0.003
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0226 0.0257 0.0296
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.7224 0.8687 1
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0329 0.0381 0.0967
Echinococcus granulosus PIK kinase FAT and Armadillo domain containing protein 0.0746 0.0883 0.0883
Trichomonas vaginalis PIKK family atypical protein kinase 0.0329 0.0381 0.1555
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0025 0.0014 0.0038
Plasmodium vivax protein kinase Crk2 0.0025 0.0014 0.0207
Brugia malayi hypothetical protein 0.0477 0.0559 0.0643
Entamoeba histolytica cyclin family protein 0.0019 0.0007 0.0034
Leishmania major phosphatidylinositol 3-kinase, putative 0.1711 0.2045 0.5395
Brugia malayi hypothetical protein 0.0059 0.0055 0.0063
Loa Loa (eye worm) hypothetical protein 0.0746 0.0883 0.1049
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0038 0.003 0.003
Entamoeba histolytica cell division protein kinase 2, putative 0.0025 0.0014 0.0069
Brugia malayi Carboxylesterase family protein 0.0017 0.0004 0.0005
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0329 0.0381 0.1847
Loa Loa (eye worm) phosphatidylinositol 3 0.1732 0.2071 0.2461
Trypanosoma brucei protein kinase, putative 0.0079 0.0079 0.0322
Echinococcus granulosus tumor protein p63 0.0417 0.0486 0.0486
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0226 0.0257 0.1247
Loa Loa (eye worm) acetylcholinesterase 1 0.0099 0.0103 0.0123
Loa Loa (eye worm) hypothetical protein 0.0021 0.0009 0.0011
Toxoplasma gondii aspartyl protease ASP1 0.0021 0.0009 0.0044
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0226 0.0257 0.1049
Mycobacterium ulcerans putative regulatory protein 0.0587 0.0691 1
Trypanosoma cruzi hypothetical protein, conserved 0.283 0.3394 0.8627
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0813 0.0964 0.3937
Schistosoma mansoni eyes absent homolog 0.0053 0.0048 0.0121
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0226 0.0257 0.0653
Trichomonas vaginalis PIKK family atypical protein kinase 0.098 0.1164 0.4756
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0038 0.003 1
Toxoplasma gondii GAF domain-containing protein 0.0587 0.0691 0.3353
Schistosoma mansoni plexin 0.0019 0.0007 0.0018
Onchocerca volvulus 0.0061 0.0058 0.0962
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0226 0.0257 0.0653
Entamoeba histolytica hypothetical protein 0.0329 0.0381 0.1838
Loa Loa (eye worm) phosphatidylinositol 3 0.2045 0.2448 0.291
Trichomonas vaginalis CMGC family protein kinase 0.0025 0.0014 0.0058
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0006 0.0019
Schistosoma mansoni tar DNA-binding protein 0.0148 0.0162 0.0412
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0038 0.003 0.0146
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0226 0.0257 0.1049
Echinococcus granulosus acetylcholinesterase 0.0099 0.0103 0.0103
Toxoplasma gondii non-specific serine/threonine protein kinase 0.1075 0.1279 0.6207
Loa Loa (eye worm) hypothetical protein 0.0198 0.0222 0.0264
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0329 0.0381 0.0967
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0226 0.0257 0.1247
Echinococcus multilocularis cyclin B 0.0019 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0477 0.0559 0.0664
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0017 0.0004 0.0011
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0021 0.0009 0.0023
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0813 0.0964 0.3937
Plasmodium vivax hypothetical protein, conserved 0.0587 0.0691 1
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0813 0.0964 0.3937
Trypanosoma cruzi hypothetical protein, conserved 0.0226 0.0257 0.0653
Trichomonas vaginalis set domain proteins, putative 0.0292 0.0336 0.1373
Schistosoma mansoni serine/threonine protein kinase 0.0025 0.0014 0.0036
Echinococcus granulosus cyclin B3 1 0.0019 0.0007 0.0007
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.3279 0.3934 1
Giardia lamblia CAMP-specific 3,5-cyclic phosphodiesterase 4B 0.0226 0.0257 0.1241
Loa Loa (eye worm) hypothetical protein 0.0038 0.003 0.0035
Loa Loa (eye worm) runx1 0.006 0.0056 0.0067
Trichomonas vaginalis cyclins, putative 0.0019 0.0007 0.0029
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.0021 0.0009 0.0009
Leishmania major phosphatidylinositol kinase related protein, putative 0.0793 0.0939 0.2477
Loa Loa (eye worm) hypothetical protein 0.0018 0.0006 0.0007
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0226 0.0257 0.1247
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0014 0.0017
Loa Loa (eye worm) hypothetical protein 0.0049 0.0043 0.0052
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.1732 0.2071 0.5264
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0329 0.0381 0.1847
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0038 0.003 1
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0329 0.0381 0.0967
Loa Loa (eye worm) phosphatidylinositol 3 0.0329 0.0381 0.0452
Brugia malayi Latrophilin receptor protein 2 0.0038 0.003 0.0034
Onchocerca volvulus 0.0329 0.0381 0.6785
Plasmodium falciparum plasmepsin IX 0.0021 0.0009 0.0132
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0006 0.0019
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0813 0.0964 0.245
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0329 0.0381 0.5507
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.0021 0.0009 0.0037
Trichomonas vaginalis PIKK family atypical protein kinase 0.109 0.1297 0.5298
Loa Loa (eye worm) hypothetical protein 0.1075 0.1279 0.152
Plasmodium falciparum ataxin-2 like protein, putative 0.0047 0.0041 0.0591
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0813 0.0964 0.3937
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0813 0.0964 0.3937
Trichomonas vaginalis PIKK family atypical protein kinase 0.1719 0.2055 0.8394
Echinococcus granulosus cyclin dependent kinase 1 0.0025 0.0014 0.0014
Trichomonas vaginalis PIKK family atypical protein kinase 0.1719 0.2055 0.8394
Schistosoma mansoni hypothetical protein 0.002 0.0008 0.002
Trichomonas vaginalis PIKK family atypical protein kinase 0.1711 0.2045 0.8354
Schistosoma mansoni cellular tumor antigen P53 0.0061 0.0058 0.0146
Loa Loa (eye worm) hypothetical protein 0.0059 0.0055 0.0065
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0037 0.0028 0.0072
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.1732 0.2071 0.2384
Brugia malayi Pre-SET motif family protein 0.0037 0.0028 0.0033
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0025 0.0014 0.0017
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0329 0.0381 0.1838
Trypanosoma brucei PAB1-binding protein , putative 0.0047 0.0041 0.0167
Trichomonas vaginalis PIKK family atypical protein kinase 0.1717 0.2053 0.8386
Giardia lamblia Kinase, CMGC CDK 0.0025 0.0014 0.0069
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0226 0.0257 0.1247
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.0813 0.0964 0.245
Plasmodium vivax acyl-CoA synthetase, putative 0.0019 0.0007 0.0098
Onchocerca volvulus 0.0198 0.0222 0.3931
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0021 0.0009 0.0023
Trichomonas vaginalis CMGC family protein kinase 0.0079 0.0079 0.0322
Loa Loa (eye worm) hypothetical protein 0.0025 0.0014 0.0017
Trichomonas vaginalis conserved hypothetical protein 0.0813 0.0964 0.3937
Leishmania major hypothetical protein, conserved 0.002 0.0008 0.002
Schistosoma mansoni hypothetical protein 0.0021 0.001 0.0024
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0329 0.0381 0.0438
Echinococcus multilocularis tar DNA binding protein 0.0148 0.0162 0.0162
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.7224 0.8687 0.8687
Echinococcus granulosus intermediate filament protein 0.0019 0.0007 0.0007
Echinococcus multilocularis cyclin b3 0.0019 0.0007 0.0007
Trypanosoma brucei cAMP phosphodiesterase A, putative 0.0226 0.0257 0.1049
Trypanosoma cruzi cdc2-related kinase 3 0.0025 0.0014 0.0036
Onchocerca volvulus 0.0019 0.0007 0.005
Schistosoma mansoni tar DNA-binding protein 0.0148 0.0162 0.0412
Leishmania major cAMP-specific phosphodiesterase, putative 0.0226 0.0257 0.0678
Trichomonas vaginalis cyclins, putative 0.0019 0.0007 0.0029
Plasmodium falciparum cyclin 0.0019 0.0007 0.0101
Loa Loa (eye worm) plexin A 0.0023 0.0012 0.0014
Schistosoma mansoni hypothetical protein 0.0079 0.0079 0.02
Trichomonas vaginalis PIKK family atypical protein kinase 0.1717 0.2053 0.8386
Loa Loa (eye worm) phosphatidylinositol 3 0.0329 0.0381 0.0452
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0329 0.0381 0.1555
Leishmania major cyclin 0.0019 0.0007 0.0018
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0029 0.0019 0.0019
Plasmodium falciparum GAF domain-related protein, putative 0.0587 0.0691 1
Giardia lamblia GTOR 0.1732 0.2071 1
Echinococcus multilocularis importin subunit beta 1 0.0018 0.0006 0.0006
Trichomonas vaginalis PIKK family atypical protein kinase 0.1717 0.2053 0.8386
Loa Loa (eye worm) hypothetical protein 0.0059 0.0055 0.0065
Leishmania major hypothetical protein, unknown function 0.0329 0.0381 0.1004
Echinococcus multilocularis cyclins 0.0019 0.0007 0.0007
Echinococcus granulosus G2:mitotic specific cyclin B3 0.0019 0.0007 0.0007
Schistosoma mansoni hypothetical protein 0.0079 0.0079 0.02
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0059 0.0055 0.0139
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0329 0.0381 0.0438
Loa Loa (eye worm) hypothetical protein 0.1099 0.1308 0.1555
Schistosoma mansoni cyclins 0.0019 0.0007 0.0018
Trypanosoma cruzi phosphatidylinositol kinase, putative 0.0329 0.0381 0.0967
Trichomonas vaginalis PIKK family atypical protein kinase 0.1724 0.2061 0.8418
Trichomonas vaginalis cyclin B, putative 0.0019 0.0007 0.0029
Trichomonas vaginalis conserved hypothetical protein 0.0587 0.0691 0.2823
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0038 0.003 0.0436
Echinococcus granulosus microtubule associated protein 2 0.1317 0.1571 0.1571
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0226 0.0257 0.1247
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0813 0.0964 0.3937
Trichomonas vaginalis conserved hypothetical protein 0.0587 0.0691 0.2823
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.0813 0.0964 0.0964
Trypanosoma cruzi cyclin 6, putative 0.0019 0.0007 0.0018
Trichomonas vaginalis PIKK family atypical protein kinase 0.1724 0.2061 0.8418
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0329 0.0381 0.1555
Leishmania major DNA polymerase eta, putative 0.0022 0.001 0.0028
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0329 0.0381 0.1847
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0099 0.0103 0.0263
Trypanosoma brucei cdc2-related kinase 1 0.0025 0.0014 0.0058
Echinococcus multilocularis cyclins 0.0019 0.0007 0.0007
Echinococcus granulosus acetylcholinesterase 0.0099 0.0103 0.0103
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0342 0.0396 0.1619
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0226 0.0257 0.0653
Plasmodium vivax stearoyl-CoA desaturase (acyl-CoA desaturase, faty acid desaturase), putative 0.0063 0.006 0.0863
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0014 0.0038
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0021 0.0009 0.0023
Giardia lamblia Hypothetical protein 0.0329 0.0381 0.1838
Brugia malayi Intermediate filament tail domain containing protein 0.0019 0.0007 0.0008
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.1732 0.2071 0.5264
Loa Loa (eye worm) hypothetical protein 0.0019 0.0007 0.0008
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0226 0.0257 0.1049
Trichomonas vaginalis PIKK family atypical protein kinase 0.0986 0.1172 0.4788
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.0014 0.0149
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0226 0.0257 0.1049
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0226 0.0257 0.1247
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.0813 0.0964 0.3937
Loa Loa (eye worm) hypothetical protein 0.0021 0.0009 0.0011
Schistosoma mansoni microtubule-associated protein tau 0.1317 0.1571 0.3992
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0813 0.0964 0.3937
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0329 0.0381 0.0967
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0813 0.0964 0.3937
Echinococcus granulosus fetal alzheimer antigen falz 0.0029 0.0019 0.0019
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0329 0.0381 0.1555
Echinococcus multilocularis plexin a4 0.0023 0.0012 0.0012
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0038 0.003 0.003
Schistosoma mansoni hypothetical protein 0.0038 0.003 0.0076
Echinococcus granulosus carboxylesterase 5A 0.0099 0.0103 0.0103
Echinococcus multilocularis protein kinase shaggy 0.0079 0.0079 0.0079
Plasmodium falciparum plasmepsin VIII, putative 0.0021 0.0009 0.0132
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0044 0.0037 0.0037
Mycobacterium tuberculosis Two component sensor histidine kinase DevS 0.0587 0.0691 1
Plasmodium vivax aspartyl proteinase, putative 0.0021 0.0009 0.0132
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0037 0.0028 0.0138
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0025 0.0014 0.0038
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0044 0.0037 0.0037
Loa Loa (eye worm) PDE1B protein 0.0226 0.0257 0.0305
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0329 0.0381 0.1555
Onchocerca volvulus 0.0025 0.0014 0.0184
Trypanosoma cruzi hypothetical protein, conserved 0.0226 0.0257 0.0653
Echinococcus multilocularis thyroid hormone receptor alpha 0.0091 0.0094 0.0094
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0813 0.0964 0.3937
Plasmodium falciparum plasmepsin V 0.0021 0.0009 0.0132
Brugia malayi hypothetical protein 0.0198 0.0222 0.0256
Loa Loa (eye worm) carboxylesterase 0.0017 0.0004 0.0005
Trypanosoma brucei importin beta-1 subunit, putative 0.0018 0.0006 0.0023
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0965 0.1147 0.2914
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0226 0.0257 0.1247
Echinococcus multilocularis peptidase Clp (S14 family) 0.0025 0.0014 0.0014
Trichomonas vaginalis conserved hypothetical protein 0.0226 0.0257 0.1049
Schistosoma mansoni hypothetical protein 0.0026 0.0016 0.0041
Echinococcus multilocularis cyclins 0.0019 0.0007 0.0007
Brugia malayi hypothetical protein 0.0021 0.0009 0.001
Plasmodium falciparum plasmepsin II 0.0021 0.0009 0.0132
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0226 0.0257 0.0296
Schistosoma mansoni hypothetical protein 0.0192 0.0215 0.0547
Loa Loa (eye worm) hypothetical protein 0.0019 0.0007 0.0008
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0329 0.0381 0.1838
Plasmodium falciparum plasmepsin VII 0.0021 0.0009 0.0132
Echinococcus multilocularis cyclin dependent kinase 1 0.0025 0.0014 0.0014
Onchocerca volvulus Huntingtin homolog 0.0059 0.0055 0.0908
Loa Loa (eye worm) hypothetical protein 0.0019 0.0007 0.0008
Echinococcus granulosus serine protein kinase ATM 0.1428 0.1705 0.1705
Echinococcus granulosus neuroligin 0.0017 0.0004 0.0004
Echinococcus granulosus high affinity cAMP specific 3'5' cyclic 0.0226 0.0257 0.0257
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0077 0.0076 0.0076
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0329 0.0381 0.0438
Plasmodium falciparum phosphatidylinositol 4-kinase 0.0329 0.0381 0.5507
Trichomonas vaginalis phosphatidylinositol 4-kinase, putative 0.0329 0.0381 0.1555
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0329 0.0381 0.0381
Echinococcus multilocularis Protein lozenge 0.006 0.0056 0.0056
Schistosoma mansoni hypothetical protein 0.0746 0.0883 0.2244
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0813 0.0964 0.3937
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0079 0.0079 0.0079
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0226 0.0257 0.0653
Trypanosoma cruzi cdc2-related kinase 1 0.0025 0.0014 0.0036
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0079 0.0079 0.0208
Trichomonas vaginalis PIKK family atypical protein kinase 0.1732 0.2071 0.8459
Trichomonas vaginalis conserved hypothetical protein 0.0587 0.0691 0.2823
Echinococcus granulosus cyclins 0.0019 0.0007 0.0007
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.1732 0.2071 1
Onchocerca volvulus 0.0329 0.0381 0.6785
Brugia malayi phosphatidylinositol 4-kinase, catalytic, alpha polypeptide 0.0329 0.0381 0.0438
Plasmodium vivax aspartyl protease, putative 0.0021 0.0009 0.0132
Echinococcus granulosus phosphatidylinositol 4 kinase alpha 0.0329 0.0381 0.0381
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0044 0.0037 0.0044
Loa Loa (eye worm) hypothetical protein 0.0019 0.0007 0.0008
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.1732 0.2071 0.5264
Plasmodium falciparum phosphatidylinositol 3- and 4-kinase, putative 0.0329 0.0381 0.5507
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.1732 0.2071 0.2071
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0329 0.0381 0.0967
Schistosoma mansoni thyroid hormone receptor 0.0091 0.0094 0.0238
Loa Loa (eye worm) hypothetical protein 0.0017 0.0004 0.0005
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0035 0.0027 0.0027
Schistosoma mansoni hypothetical protein 0.0082 0.0083 0.021
Plasmodium falciparum protein kinase 5 0.0025 0.0014 0.0207
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.0021 0.0009 0.0044
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.3279 0.3934 0.3934
Giardia lamblia Phosphoinositide-3-kinase, class 3 0.0329 0.0381 0.1838
Giardia lamblia hypothetical protein 0.0226 0.0257 0.1241
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.1428 0.1705 0.1962
Schistosoma mansoni hypothetical protein 0.0038 0.003 0.0076
Brugia malayi Cyclin, N-terminal domain containing protein 0.0019 0.0007 0.0008
Loa Loa (eye worm) hypothetical protein 0.0019 0.0007 0.0008
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0046 0.004 0.004
Trichomonas vaginalis PIKK family atypical protein kinase 0.0978 0.1162 0.4748
Brugia malayi aspartic protease BmAsp-1, identical 0.0021 0.0009 0.001
Loa Loa (eye worm) hypothetical protein 0.0052 0.0047 0.0056
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0813 0.0964 0.3937
Loa Loa (eye worm) phosphatidylinositol 3 0.0329 0.0381 0.0452
Entamoeba histolytica hypothetical protein 0.1428 0.1705 0.8232

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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