Detailed information for compound 1052161

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 365.469 | Formula: C22H27N3O2
  • H donors: 2 H acceptors: 2 LogP: 2.68 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: CNC[C@H]([C@@H](n1c(=O)n(c2c1cccc2)C1CCCC1)c1ccccc1)O
  • InChi: 1S/C22H27N3O2/c1-23-15-20(26)21(16-9-3-2-4-10-16)25-19-14-8-7-13-18(19)24(22(25)27)17-11-5-6-12-17/h2-4,7-10,13-14,17,20-21,23,26H,5-6,11-12,15H2,1H3/t20-,21+/m1/s1
  • InChiKey: PUQYZIQIINNNTQ-RTWAWAEBSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens solute carrier family 6 (neurotransmitter transporter), member 2 Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Schistosoma japonicum Sodium-dependent dopamine transporter, putative Get druggable targets OG5_128364 All targets in OG5_128364
Loa Loa (eye worm) norepinephrine transporter Get druggable targets OG5_128364 All targets in OG5_128364
Onchocerca volvulus Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma mansoni norepinephrine/norepinephrine transporter Get druggable targets OG5_128364 All targets in OG5_128364
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma japonicum ko:K05336 solute carrier family 6 (neurotransmitter transporter), invertebrate, putative Get druggable targets OG5_128364 All targets in OG5_128364
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128364 All targets in OG5_128364
Echinococcus multilocularis serotonin transporter Get druggable targets OG5_128364 All targets in OG5_128364
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128364 All targets in OG5_128364
Loa Loa (eye worm) serotonin transporter b Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma japonicum Sodium-dependent noradrenaline transporter, putative Get druggable targets OG5_128364 All targets in OG5_128364
Brugia malayi Sodium:neurotransmitter symporter family protein Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma japonicum Sodium-dependent dopamine transporter, putative Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma japonicum IPR000175,Sodium:neurotransmitter symporter,domain-containing Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma mansoni sodium/chloride dependent transporter Get druggable targets OG5_128364 All targets in OG5_128364
Loa Loa (eye worm) solute carrier family 6 member 4 Get druggable targets OG5_128364 All targets in OG5_128364
Echinococcus granulosus serotonin transporter Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma japonicum Sodium-dependent dopamine transporter, putative Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma japonicum Sodium-dependent dopamine transporter, putative Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma japonicum Sodium-dependent dopamine transporter, putative Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma japonicum Sodium-dependent dopamine transporter, putative Get druggable targets OG5_128364 All targets in OG5_128364
Treponema pallidum sodium- and chloride- dependent transporter Get druggable targets OG5_128364 All targets in OG5_128364
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Brugia malayi Sodium:neurotransmitter symporter family protein solute carrier family 6 (neurotransmitter transporter), member 2 617 aa 638 aa 32.5 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni serine/threonine protein kinase 0.3062 0.3044 0.7606
Trichomonas vaginalis CAMK family protein kinase 0.0372 0.0144 0.1202
Echinococcus multilocularis serine:threonine protein kinase 0.0341 0.011 0.011
Echinococcus multilocularis titin 0.0408 0.0183 0.0183
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.2089 0.1996 0.1996
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.026 0.0023 0.0023
Brugia malayi Protein kinase domain containing protein 0.026 0.0023 0.0026
Loa Loa (eye worm) AGC/PKN protein kinase 0.1788 0.1671 0.2169
Trypanosoma cruzi casein kinase, putative 0.0645 0.0439 0.0707
Trypanosoma cruzi cdc2-related kinase 1 0.0484 0.0265 0.0426
Echinococcus multilocularis tyrosine protein kinase shark 0.071 0.0508 0.0508
Schistosoma mansoni hypothetical protein 0.0353 0.0124 0.0301
Loa Loa (eye worm) hypothetical protein 0.026 0.0023 0.0026
Entamoeba histolytica protein kinase, putative 0.026 0.0023 0.0175
Schistosoma mansoni serine/threonine protein kinase 0.0372 0.0144 0.0351
Loa Loa (eye worm) hypothetical protein 0.0353 0.0124 0.0157
Trypanosoma cruzi cdc2-related kinase 3 0.0484 0.0265 0.0426
Echinococcus granulosus tyrosine protein kinase Btk29A 0.2472 0.2408 0.391
Echinococcus granulosus maternal embryonic leucine zipper kinase 0.0257 0.002 0.0027
Loa Loa (eye worm) TK/FER protein kinase 0.0488 0.027 0.0347
Entamoeba histolytica protein kinase domain containing protein 0.0405 0.018 0.1578
Loa Loa (eye worm) TK protein kinase 0.026 0.0023 0.0026
Onchocerca volvulus 0.0488 0.027 0.0322
Echinococcus multilocularis casein kinase I delta 0.0645 0.0439 0.0439
Entamoeba histolytica ankyrin repeat protein 0.026 0.0023 0.0175
Echinococcus granulosus casein kinase i 0.0645 0.0439 0.0707
Echinococcus multilocularis peroxidasin 0.0299 0.0065 0.0065
Onchocerca volvulus 0.0995 0.0816 0.1034
Entamoeba histolytica protein kinase domain containing protein 0.026 0.0023 0.0175
Brugia malayi intracellular kinase 0.1218 0.1057 0.1371
Loa Loa (eye worm) hypothetical protein 0.0353 0.0124 0.0157
Trypanosoma cruzi rac serine-threonine kinase, putative 0.03 0.0066 0.0103
Echinococcus granulosus slit 2 protein 0.0287 0.0053 0.008
Entamoeba histolytica protein kinase domain containing protein 0.026 0.0023 0.0175
Brugia malayi Protein kinase domain containing protein 0.0346 0.0116 0.0146
Brugia malayi putative serine/threonine kinase SADA gamma 0.0372 0.0144 0.0183
Echinococcus multilocularis casein kinase ii subunit alpha 0.0241 0.0003 0.0003
Schistosoma mansoni nck2/grb4 0.0409 0.0184 0.0451
Brugia malayi Immunoglobulin I-set domain containing protein 0.3684 0.3714 0.4829
Trichomonas vaginalis AGC family protein kinase 0.0279 0.0044 0.0344
Echinococcus granulosus casein kinase I delta 0.0645 0.0439 0.0707
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0279 0.0044 0.0382
Echinococcus granulosus tyrosine protein kinase Src42A 0.0703 0.0501 0.0809
Trichomonas vaginalis br serine/threonine-protein kinase, putative 0.026 0.0023 0.0168
Loa Loa (eye worm) TK/EGFR protein kinase 0.1054 0.088 0.1141
Entamoeba histolytica serine/threonine protein kinase, putative 0.032 0.0088 0.0754
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0372 0.0144 0.0228
Schistosoma mansoni tyrosine kinase 0.0651 0.0445 0.1105
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.0985 0.0805 0.1043
Echinococcus granulosus hypothetical protein 0.094 0.0757 0.1225
Echinococcus multilocularis atrial natriuretic peptide receptor 1 0.026 0.0023 0.0023
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0579 0.0367 0.0367
Schistosoma mansoni serine/threonine protein kinase 0.2933 0.2905 0.726
Trichomonas vaginalis CK1 family protein kinase 0.0645 0.0439 0.3723
Schistosoma mansoni serine/threonine protein kinase 0.0372 0.0144 0.0351
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.1218 0.1057 0.1713
Loa Loa (eye worm) hypothetical protein 0.0593 0.0382 0.0493
Plasmodium vivax casein kinase 1, putative 0.0645 0.0439 0.4131
Trichomonas vaginalis TKL family protein kinase 0.026 0.0023 0.0168
Trichomonas vaginalis TKL family protein kinase 0.026 0.0023 0.0168
Trichomonas vaginalis TKL family protein kinase 0.026 0.0023 0.0168
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0639 0.0432 0.0697
Leishmania major protein kinase A catalytic subunit isoform 1 0.0794 0.0599 0.0969
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0346 0.0117 0.0184
Trichomonas vaginalis CMGC family protein kinase 0.0282 0.0047 0.0371
Giardia lamblia Kinase, NEK 0.026 0.0023 0.0168
Echinococcus multilocularis 0.0985 0.0805 0.0805
Trichomonas vaginalis STE family protein kinase 0.1326 0.1172 1
Schistosoma mansoni src-type protein tyrosine kinase-related 0.026 0.0023 0.0049
Leishmania major protein kinase A catalytic subunit isoform 2 0.0794 0.0599 0.0969
Schistosoma mansoni protein kinase 0.026 0.0023 0.0049
Echinococcus multilocularis protein kinase 0.026 0.0023 0.0023
Echinococcus granulosus insulin receptor 0.1436 0.1291 0.2093
Plasmodium vivax serine/threonine kinase-1, putative 0.1112 0.0942 0.8912
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0372 0.0144 0.0228
Echinococcus multilocularis mitogen activated protein kinase 11 0.5947 0.6154 0.6154
Schistosoma mansoni tyrosine kinase 0.3949 0.4001 1
Echinococcus multilocularis STE20 serine:threonine protein kinase 0.065 0.0444 0.0444
Schistosoma mansoni titin 0.0295 0.0062 0.0146
Trichomonas vaginalis TKL family protein kinase 0.026 0.0023 0.0168
Echinococcus granulosus serine:threonine protein kinase MARK2 0.051 0.0293 0.0471
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.072 0.0519 0.0838
Echinococcus multilocularis growth factor receptor bound protein 2 0.0409 0.0184 0.0184
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0473 0.0253 0.0406
Plasmodium vivax tyrosine kinase-like protein, putative 0.026 0.0023 0.0186
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.026 0.0023 0.0175
Giardia lamblia Protein 21.1 0.026 0.0023 0.0168
Entamoeba histolytica tyrosin kinase, putative 0.0308 0.0076 0.0646
Trichomonas vaginalis CAMK family protein kinase 0.0372 0.0144 0.1202
Loa Loa (eye worm) hypothetical protein 0.026 0.0023 0.0026
Echinococcus multilocularis calcium dependent protein kinase 0.0407 0.0182 0.0182
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0579 0.0367 0.0592
Brugia malayi p70 ribosomal S6 kinase beta 0.0699 0.0496 0.0642
Schistosoma mansoni serine/threonine protein kinase 0.0319 0.0088 0.021
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.1112 0.0942 0.1526
Echinococcus multilocularis rac serine:threonine kinase 0.0346 0.0117 0.0117
Echinococcus multilocularis cyclin dependent kinase 19 0.1812 0.1696 0.1696
Trichomonas vaginalis TKL family protein kinase 0.026 0.0023 0.0168
Echinococcus granulosus tyrosine protein kinase shark 0.071 0.0508 0.0821
Trichomonas vaginalis AGC family protein kinase 0.0745 0.0547 0.4647
Schistosoma mansoni adapter molecule crk 0.0409 0.0184 0.0451
Schistosoma mansoni vav2 0.0437 0.0215 0.0528
Brugia malayi Protein kinase domain containing protein 0.026 0.0023 0.0026
Entamoeba histolytica PH domain containing protein kinase, putative 0.0346 0.0117 0.1014
Loa Loa (eye worm) TK protein kinase 0.0717 0.0516 0.0667
Entamoeba histolytica PH domain containing protein kinase, putative 0.0841 0.0649 0.5781
Loa Loa (eye worm) hypothetical protein 0.072 0.0519 0.0671
Plasmodium falciparum tyrosine kinase-like protein 0.026 0.0023 0.0186
Echinococcus multilocularis serine:threonine protein kinase N2 0.1217 0.1055 0.1055
Trichomonas vaginalis TKL family protein kinase 0.026 0.0023 0.0168
Brugia malayi EGF-like domain containing protein 0.0287 0.0053 0.0064
Brugia malayi Raf kinase 0.026 0.0023 0.0026
Brugia malayi hypothetical protein 0.072 0.0519 0.0671
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0391 0.0164 0.0209
Echinococcus multilocularis transfer RNA-Thr 0.1815 0.17 0.17
Schistosoma mansoni protein tyrosine kinase 0.026 0.0023 0.0049
Echinococcus multilocularis mitogen activated protein kinase 14 0.5947 0.6154 0.6154
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.1446 0.1302 0.1302
Echinococcus granulosus serine:threonine kinase SAD 1 0.0372 0.0144 0.0228
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0277 0.0041 0.005
Trichomonas vaginalis conserved hypothetical protein 0.026 0.0023 0.0168
Entamoeba histolytica tyrosine kinase, putative 0.026 0.0023 0.0175
Brugia malayi Variant SH3 domain containing protein 0.0391 0.0164 0.0209
Loa Loa (eye worm) hypothetical protein 0.0295 0.0062 0.0076
Loa Loa (eye worm) TK/FER protein kinase 0.026 0.0023 0.0026
Schistosoma mansoni tyrosine-protein kinase fps85d 0.026 0.0023 0.0049
Loa Loa (eye worm) hypothetical protein 0.0295 0.0062 0.0076
Entamoeba histolytica protein kinase domain containing protein 0.026 0.0023 0.0175
Echinococcus granulosus serine threonine protein kinase nrc 0.03 0.0066 0.0103
Brugia malayi Protein kinase domain containing protein 0.0602 0.0393 0.0506
Loa Loa (eye worm) hypothetical protein 0.026 0.0023 0.0026
Entamoeba histolytica hypothetical protein 0.0263 0.0026 0.0206
Echinococcus multilocularis tyrosine protein kinase Fyn 0.1126 0.0957 0.0957
Giardia lamblia Kinase, NEK 0.0279 0.0044 0.0344
Entamoeba histolytica protein kinase domain containing protein 0.0639 0.0432 0.3835
Echinococcus multilocularis MAM 0.0353 0.0124 0.0124
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0794 0.0599 0.5658
Schistosoma mansoni protein kinase 0.2543 0.2484 0.6207
Trichomonas vaginalis STE family protein kinase 0.1326 0.1172 1
Brugia malayi Protein kinase domain containing protein 0.2077 0.1982 0.2574
Brugia malayi cyclin-dependent kinase 7 homolog 0.0692 0.0489 0.0632
Loa Loa (eye worm) hypothetical protein 0.0699 0.0496 0.0642
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.1126 0.0957 0.0957
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.072 0.0519 0.0838
Echinococcus multilocularis G protein coupled receptor kinase 6 0.15 0.1361 0.1361
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.1126 0.0957 0.0957
Trichomonas vaginalis CAMK family protein kinase 0.0257 0.002 0.0143
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0622 0.0414 0.0414
Schistosoma mansoni roundabout 0.0295 0.0062 0.0146
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0794 0.0599 0.0969
Echinococcus granulosus serine:threonine protein kinase mig 15 0.1533 0.1395 0.2263
Echinococcus multilocularis tyrosine protein kinase HCK 0.0717 0.0516 0.0516
Echinococcus multilocularis roundabout 2 0.0994 0.0815 0.0815
Echinococcus granulosus protein kinase C gamma type 0.0613 0.0404 0.0651
Echinococcus multilocularis neurotracting:lsamp:neurotrimin:obcam 0.0295 0.0062 0.0062
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.026 0.0023 0.0175
Trichomonas vaginalis CAMK family protein kinase 0.032 0.0088 0.0721
Echinococcus granulosus cGMP dependent protein kinase 1 0.0277 0.0042 0.0063
Loa Loa (eye worm) hypothetical protein 0.0275 0.004 0.0048
Schistosoma mansoni septate junction protein 0.0295 0.0062 0.0146
Schistosoma mansoni tyrosine kinase 0.1126 0.0957 0.2385
Echinococcus granulosus neuroglian 0.0862 0.0673 0.1088
Brugia malayi C1-like domain containing protein 0.112 0.0951 0.1233
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.072 0.0519 0.0519
Entamoeba histolytica protein kinase, putative 0.026 0.0023 0.0175
Brugia malayi Immunoglobulin I-set domain containing protein 0.0408 0.0183 0.0233
Echinococcus granulosus retinal guanylyl cyclase 2 0.026 0.0023 0.0032
Entamoeba histolytica protein kinase, putative 0.026 0.0023 0.0175
Entamoeba histolytica protein kinase, putative 0.0282 0.0047 0.0388
Trichomonas vaginalis AGC family protein kinase 0.0794 0.0599 0.5098
Brugia malayi serine/threonine kinase 12 0.0639 0.0432 0.0558
Schistosoma mansoni tyrosine protein kinase 0.026 0.0023 0.0049
Echinococcus granulosus lachesin 0.0295 0.0062 0.0095
Trichomonas vaginalis TKL family protein kinase 0.026 0.0023 0.0168
Plasmodium vivax protein kinase, putative 0.0275 0.004 0.0346
Trichomonas vaginalis CMGC family protein kinase 0.0282 0.0047 0.0371
Echinococcus granulosus titin 0.0408 0.0183 0.0292
Echinococcus granulosus tyrosine protein kinase otk 0.0295 0.0062 0.0095
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.1112 0.0942 0.1526
Echinococcus multilocularis serine:threonine protein kinase receptor R3 0.0921 0.0736 0.0736
Leishmania major hypothetical protein, conserved 0.026 0.0023 0.0032
Schistosoma mansoni protein kinase 0.026 0.0023 0.0049
Loa Loa (eye worm) camk/dcamkl protein kinase 0.0294 0.006 0.0074
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.112 0.0951 0.1233
Brugia malayi Protein kinase domain containing protein 0.026 0.0023 0.0026
Schistosoma mansoni serine/threonine protein kinase 0.1787 0.167 0.4169
Echinococcus multilocularis FL cytokine receptor 0.026 0.0023 0.0023
Brugia malayi Protein kinase domain containing protein 0.0488 0.027 0.0347
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.2472 0.2408 0.2408
Trypanosoma cruzi protein kinase, putative 0.026 0.0023 0.0032
Brugia malayi Immunoglobulin I-set domain containing protein 0.0295 0.0062 0.0076
Trichomonas vaginalis CMGC family protein kinase 0.0282 0.0047 0.0371
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.0602 0.0393 0.0506
Echinococcus multilocularis natriuretic peptide receptor 1 0.026 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0478 0.0258 0.0332
Entamoeba histolytica protein kinase domain containing protein 0.026 0.0023 0.0175
Loa Loa (eye worm) hypothetical protein 0.0995 0.0816 0.1057
Echinococcus multilocularis dual specificity 0.0282 0.0047 0.0047
Echinococcus granulosus casein kinase I alpha 0.0645 0.0439 0.0707
Brugia malayi Protein kinase domain containing protein 0.026 0.0023 0.0026
Loa Loa (eye worm) hypothetical protein 0.0295 0.0062 0.0076
Schistosoma mansoni tyrosine kinase 0.1126 0.0957 0.2385
Loa Loa (eye worm) hypothetical protein 0.0341 0.011 0.0139
Brugia malayi Stress-activated protein kinase jnk-1 0.3062 0.3044 0.3956
Loa Loa (eye worm) TKL/STKR/TYPE2 protein kinase 0.081 0.0617 0.0798
Trichomonas vaginalis TKL family protein kinase 0.026 0.0023 0.0168
Brugia malayi hypothetical protein 0.0353 0.0124 0.0157
Echinococcus multilocularis hemicentin 1 0.0295 0.0062 0.0062
Loa Loa (eye worm) hypothetical protein 0.0758 0.0561 0.0725
Giardia lamblia Kinase, CMGC CLK 0.1112 0.0942 0.8031
Giardia lamblia Kinase, STE STE20 0.039 0.0163 0.1369
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.026 0.0023 0.0049
Loa Loa (eye worm) hypothetical protein 0.1555 0.142 0.1843
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.1075 0.0902 0.117
Trichomonas vaginalis TKL family protein kinase 0.026 0.0023 0.0168
Brugia malayi Protein kinase domain containing protein 0.1812 0.1696 0.2203
Echinococcus multilocularis tyrosine protein kinase ABL1 0.2432 0.2364 0.2364
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.1112 0.0942 0.1526
Entamoeba histolytica tyrosine kinase, putative 0.026 0.0023 0.0175
Trichomonas vaginalis TKL family protein kinase 0.026 0.0023 0.0168
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0794 0.0599 0.5658
Loa Loa (eye worm) hypothetical protein 0.0699 0.0496 0.0642
Echinococcus multilocularis ephrin type A receptor 4 A 0.0326 0.0094 0.0094
Echinococcus granulosus cGMP dependent protein kinase 1 0.0277 0.0042 0.0063
Loa Loa (eye worm) TK/FER protein kinase 0.0488 0.027 0.0347
Giardia lamblia Kinase, NEK 0.026 0.0023 0.0168
Loa Loa (eye worm) CAMK/PHK protein kinase 0.0308 0.0075 0.0093
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0639 0.0432 0.3835
Trichomonas vaginalis TKL family protein kinase 0.026 0.0023 0.0168
Leishmania major protein kinase, putative 0.026 0.0023 0.0032
Trichomonas vaginalis TK family protein kinase 0.026 0.0023 0.0168
Brugia malayi Protein kinase domain containing protein 0.026 0.0023 0.0026
Onchocerca volvulus 0.0645 0.0439 0.0542
Brugia malayi Temporarily assigned gene name protein 59 0.072 0.0519 0.0671
Loa Loa (eye worm) TK/FER protein kinase 0.026 0.0023 0.0026
Brugia malayi Protein kinase domain containing protein 0.1278 0.1121 0.1454
Loa Loa (eye worm) TK/FER protein kinase 0.026 0.0023 0.0026
Loa Loa (eye worm) hypothetical protein 0.0699 0.0496 0.0642
Loa Loa (eye worm) hypothetical protein 0.0372 0.0144 0.0183
Loa Loa (eye worm) hypothetical protein 0.0353 0.0124 0.0157
Schistosoma mansoni cell adhesion molecule 0.0332 0.0101 0.0243
Echinococcus multilocularis tyrosine protein kinase 0.026 0.0023 0.0023
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0459 0.0238 0.0382
Loa Loa (eye worm) TK/FER protein kinase 0.026 0.0023 0.0026
Brugia malayi SRC-1 0.1126 0.0957 0.124
Plasmodium falciparum protein kinase, putative 0.026 0.0023 0.0186
Entamoeba histolytica PH domain containing protein kinase, putative 0.0346 0.0117 0.1014
Echinococcus granulosus serine:threonine protein kinase 0.0341 0.011 0.0174
Loa Loa (eye worm) RGC/RGC protein kinase 0.026 0.0023 0.0026
Schistosoma mansoni hypothetical protein 0.072 0.0519 0.129
Trichomonas vaginalis CAMK family protein kinase 0.0372 0.0144 0.1202
Schistosoma mansoni nephrin 0.0332 0.0101 0.0243
Entamoeba histolytica tyrosine kinase, putative 0.026 0.0023 0.0175
Loa Loa (eye worm) CMGC/CDK/CDK8 protein kinase 0.1812 0.1696 0.2203
Trichomonas vaginalis TKL family protein kinase 0.026 0.0023 0.0168
Loa Loa (eye worm) hypothetical protein 0.0543 0.0329 0.0423
Echinococcus granulosus activated cdc42 kinase 1 0.1815 0.17 0.2758
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0662 0.0457 0.0457
Echinococcus granulosus mitogen activated protein kinase 14 0.5947 0.6154 1
Entamoeba histolytica protein kinase, putative 0.026 0.0023 0.0175
Echinococcus multilocularis aurora kinase A 0.0639 0.0432 0.0432
Brugia malayi hypothetical protein 0.0699 0.0496 0.0642
Echinococcus multilocularis tyrosine protein kinase pr2 0.026 0.0023 0.0023
Trichomonas vaginalis conserved hypothetical protein 0.026 0.0023 0.0168
Brugia malayi hypothetical protein 0.2933 0.2905 0.3776
Echinococcus multilocularis neuroglian 0.0862 0.0673 0.0673
Loa Loa (eye worm) hypothetical protein 0.0287 0.0053 0.0064
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.1112 0.0942 0.1526
Echinococcus granulosus cyclin dependent kinase 19 0.1812 0.1696 0.2753
Brugia malayi C-terminal src kinase protein 1 0.026 0.0023 0.0026
Trichomonas vaginalis TKL family protein kinase 0.026 0.0023 0.0168
Brugia malayi Immunoglobulin I-set domain containing protein 0.1699 0.1574 0.2044
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.2334 0.2259 0.3667
Trichomonas vaginalis CMGC family protein kinase 0.1218 0.1057 0.9011
Schistosoma mansoni protein kinase 0.2507 0.2446 0.611
Entamoeba histolytica hypothetical protein 0.026 0.0023 0.0175
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.1218 0.1057 0.1713
Entamoeba histolytica tyrosin kinase, putative 0.026 0.0023 0.0175
Echinococcus granulosus beta-adrenergic receptor kinase 0.0319 0.0088 0.0137
Loa Loa (eye worm) STE/STE20/SLK protein kinase 0.0337 0.0107 0.0135
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.026 0.0023 0.0175
Trichomonas vaginalis TKL family protein kinase 0.026 0.0023 0.0168
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0332 0.0101 0.0101
Trichomonas vaginalis CAMK family protein kinase 0.026 0.0023 0.0168
Trichomonas vaginalis TKL family protein kinase 0.026 0.0023 0.0168
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.1112 0.0942 0.1526
Trichomonas vaginalis TKL family protein kinase 0.026 0.0023 0.0168
Loa Loa (eye worm) hypothetical protein 0.0639 0.0432 0.0557
Loa Loa (eye worm) CAMK/PIM protein kinase 0.2334 0.2259 0.2935
Brugia malayi Protein kinase domain containing protein 0.0852 0.0662 0.0857
Entamoeba histolytica hypothetical protein 0.026 0.0023 0.0175
Echinococcus multilocularis epidermal growth factor receptor 0.1054 0.088 0.088
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.2089 0.1996 0.3239
Schistosoma mansoni tyrosine kinase 0.026 0.0023 0.0049
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0794 0.0599 0.0775
Brugia malayi Protein kinase domain containing protein 0.0484 0.0265 0.0341
Loa Loa (eye worm) TK/FER protein kinase 0.0488 0.027 0.0347
Entamoeba histolytica cysteine surface protein, putative 0.026 0.0023 0.0175
Loa Loa (eye worm) TK protein kinase 0.026 0.0023 0.0026
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0391 0.0164 0.0164
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.026 0.0023 0.0175
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0431 0.0208 0.1945
Giardia lamblia Kinase, STE STE20 0.1326 0.1172 1
Loa Loa (eye worm) RGC/RGC protein kinase 0.026 0.0023 0.0026
Trichomonas vaginalis AGC family protein kinase 0.0639 0.0432 0.3667
Trichomonas vaginalis TKL family protein kinase 0.026 0.0023 0.0168
Trichomonas vaginalis AGC family protein kinase 0.0617 0.0408 0.3466
Schistosoma mansoni tyrosine-protein kinase fps85d 0.026 0.0023 0.0049
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0391 0.0164 0.0262
Schistosoma mansoni serine/threonine protein kinase 0.1812 0.1696 0.4236
Brugia malayi Protein kinase domain containing protein 0.026 0.0023 0.0026
Echinococcus granulosus cyclin dependent kinase 5 0.0484 0.0265 0.0426
Brugia malayi Protein kinase domain containing protein 0.0571 0.0358 0.0462
Echinococcus granulosus NDR protein kinase 0.0571 0.0358 0.0577
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0794 0.0599 0.0599
Echinococcus multilocularis phosphorylase kinase gamma subunit 0.0308 0.0075 0.0075
Echinococcus granulosus [G-protein-coupledreceptor] kinase 0.15 0.1361 0.2207
Echinococcus multilocularis dual specificity 0.0282 0.0047 0.0047
Trypanosoma cruzi casein kinase, putative 0.0645 0.0439 0.0707
Trypanosoma brucei casein kinase I, isoform 2 0.0645 0.0439 0.0707
Echinococcus granulosus cGMP dependent protein kinase 0.0277 0.0042 0.0063
Echinococcus granulosus dual specificity 0.0282 0.0047 0.0071
Schistosoma mansoni ephrin receptor 0.0296 0.0062 0.0147
Leishmania major protein kinase, putative 0.1112 0.0942 0.1526
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.1126 0.0957 0.155
Echinococcus multilocularis c src tyrosine kinase 0.0668 0.0464 0.0464
Entamoeba histolytica protein kinase, putative 0.026 0.0023 0.0175
Echinococcus multilocularis protein kinase c iota type 0.0818 0.0625 0.0625
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0484 0.0265 0.0341
Loa Loa (eye worm) TK/Met protein kinase 0.026 0.0023 0.0026
Trichomonas vaginalis CMGC family protein kinase 0.0282 0.0047 0.0371
Loa Loa (eye worm) TK/FER protein kinase 0.026 0.0023 0.0026
Entamoeba histolytica protein kinase domain containing protein 0.1218 0.1057 0.9425
Echinococcus granulosus cyclin dependent kinase 0.0484 0.0265 0.0426
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0579 0.0367 0.0367
Echinococcus multilocularis activated cdc42 kinase 1 0.1815 0.17 0.17
Entamoeba histolytica protein kinase, putative 0.026 0.0023 0.0175
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.0372 0.0144 0.0228
Echinococcus granulosus epidermal growth factor receptor 0.0911 0.0725 0.1173
Entamoeba histolytica tyrosin kinase, putative 0.026 0.0023 0.0175
Brugia malayi Variant SH3 domain containing protein 0.0277 0.0041 0.005
Brugia malayi Protein kinase domain containing protein 0.026 0.0023 0.0026
Trichomonas vaginalis STE family protein kinase 0.1326 0.1172 1
Brugia malayi Cam kinase protein 1 0.0579 0.0367 0.0474
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.026 0.0023 0.0026
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0579 0.0367 0.0367
Brugia malayi Serine/threonine-protein kinase Pim-3 0.2334 0.2259 0.2935
Trichomonas vaginalis TKL family protein kinase 0.026 0.0023 0.0168
Trichomonas vaginalis TKL family protein kinase 0.026 0.0023 0.0168
Loa Loa (eye worm) hypothetical protein 0.1003 0.0824 0.1068
Schistosoma mansoni serine/threonine protein kinase 0.0632 0.0424 0.1053
Brugia malayi Protein kinase domain containing protein 0.3993 0.4048 0.5263
Schistosoma mansoni serine/threonine protein kinase 0.1075 0.0902 0.2249
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0484 0.0265 0.0426
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.1218 0.1057 0.1057
Echinococcus granulosus tyrosine kinase 0.0488 0.027 0.0433
Brugia malayi ephrin receptor 1 precursor 0.0291 0.0057 0.0069
Brugia malayi Protein kinase domain containing protein 0.026 0.0023 0.0026
Brugia malayi Immunoglobulin I-set domain containing protein 0.0295 0.0062 0.0076
Trichomonas vaginalis STE family protein kinase 0.039 0.0163 0.1369
Plasmodium falciparum calcium-dependent protein kinase 3 0.0579 0.0367 0.3456
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0645 0.0439 0.0566
Loa Loa (eye worm) hypothetical protein 0.026 0.0023 0.0026
Trichomonas vaginalis STE family protein kinase 0.039 0.0163 0.1369
Onchocerca volvulus Serine\/threonine kinase homolog 0.0308 0.0075 0.0068
Echinococcus granulosus serine/threonine protein kinase 0.0346 0.0117 0.0184
Schistosoma mansoni serine/threonine protein kinase 0.0775 0.0578 0.1439
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0431 0.0208 0.0333
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0332 0.0101 0.0158
Echinococcus multilocularis protein kinase shaggy 0.1218 0.1057 0.1057
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.1075 0.0902 0.1461
Loa Loa (eye worm) TK/ALK protein kinase 0.522 0.5371 0.6984
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0579 0.0367 0.3456
Trichomonas vaginalis TKL family protein kinase 0.026 0.0023 0.0168
Giardia lamblia Kinase, CMGC DYRK 0.0282 0.0047 0.0371
Trichomonas vaginalis TKL family protein kinase 0.026 0.0023 0.0168
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.1126 0.0957 0.0957
Plasmodium vivax protein kinase Crk2 0.0484 0.0265 0.2485
Entamoeba histolytica cell division protein kinase 2, putative 0.0525 0.0309 0.2737
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0579 0.0367 0.0474
Echinococcus multilocularis macrophage colony stimulating factor 1 receptor 0.026 0.0023 0.0023
Brugia malayi hypothetical protein 0.0488 0.027 0.0347
Schistosoma mansoni serine/threonine protein kinase 0.0571 0.0358 0.0888
Entamoeba histolytica protein kinase, putative 0.0745 0.0547 0.486
Schistosoma mansoni serine/threonine protein kinase 0.1648 0.152 0.3793
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.039 0.0163 0.026
Echinococcus granulosus tyrosine protein kinase csk 0.026 0.0023 0.0032
Loa Loa (eye worm) hypothetical protein 0.0786 0.0591 0.0765
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.039 0.0163 0.0163
Echinococcus multilocularis receptor type guanylyl cyclase 0.026 0.0023 0.0023
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0645 0.0439 0.0566
Schistosoma mansoni vesicular amine transporter 0.0662 0.0457 0.1136
Schistosoma mansoni cell adhesion molecule 0.0332 0.0101 0.0243
Echinococcus granulosus STE20 serine:threonine protein kinase 0.065 0.0444 0.0716
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0639 0.0432 0.4069
Echinococcus multilocularis casein kinase I delta 0.0645 0.0439 0.0439
Brugia malayi Immunoglobulin I-set domain containing protein 0.0332 0.0101 0.0127
Schistosoma mansoni protein kinase 0.0431 0.0208 0.0512
Loa Loa (eye worm) TK/FER protein kinase 0.0803 0.0609 0.0787
Echinococcus multilocularis serine:threonine protein kinase 38 0.0571 0.0358 0.0358
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0794 0.0599 0.0969
Loa Loa (eye worm) hypothetical protein 0.0543 0.0329 0.0423
Trichomonas vaginalis TKL family protein kinase 0.026 0.0023 0.0168
Echinococcus granulosus aurora kinase A 0.0639 0.0432 0.0697
Leishmania major protein kinase, putative 0.0639 0.0432 0.0697
Echinococcus granulosus cyclin dependent kinase 9 0.0446 0.0224 0.0358
Echinococcus multilocularis slit 2 protein 0.0287 0.0053 0.0053
Echinococcus granulosus protein kinase shaggy 0.1218 0.1057 0.1713
Schistosoma mansoni serine/threonine protein kinase 0.0408 0.0183 0.0449
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0503 0.0286 0.0368
Schistosoma mansoni serine/threonine protein kinase 0.051 0.0293 0.0725
Onchocerca volvulus 0.0389 0.0163 0.0183
Echinococcus granulosus tyrosine protein kinase Src64B 0.1126 0.0957 0.155
Echinococcus multilocularis casein kinase I alpha 0.0645 0.0439 0.0439
Schistosoma mansoni kinase 0.0387 0.016 0.0393
Echinococcus multilocularis tyrosine protein kinase csk 0.026 0.0023 0.0023
Brugia malayi probable protein kinase 0.1705 0.1581 0.2052
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0794 0.0599 0.5658
Toxoplasma gondii aurora kinase 0.0639 0.0432 0.4069
Plasmodium falciparum calcium-dependent protein kinase 1 0.0579 0.0367 0.3456
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.2543 0.2484 0.2484
Schistosoma mansoni tyrosine kinase 0.1436 0.1291 0.3221
Echinococcus granulosus leucine rich repeat serine:threonine protein 0.0478 0.0258 0.0414
Plasmodium falciparum glycogen synthase kinase 3 0.1218 0.1057 1
Echinococcus granulosus calcium dependent protein kinase 0.0407 0.0182 0.0291
Echinococcus granulosus c src tyrosine kinase 0.0668 0.0464 0.0748
Entamoeba histolytica protein kinase domain containing protein 0.0348 0.0118 0.1024
Trichomonas vaginalis CAMK family protein kinase 0.0372 0.0144 0.1202
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.039 0.0163 0.0163
Schistosoma mansoni hypothetical protein 0.0353 0.0124 0.0301
Brugia malayi Homeodomain interacting protein kinase protein 1 0.0348 0.0118 0.0149
Onchocerca volvulus 0.737 0.7689 1
Loa Loa (eye worm) G protein-coupled receptor kinase 1 0.15 0.1361 0.1766
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.072 0.0519 0.0838
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0279 0.0044 0.0382
Schistosoma mansoni serine/threonine protein kinase 0.0371 0.0144 0.0351
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.026 0.0023 0.0175
Entamoeba histolytica tyrosine kinase, putative 0.026 0.0023 0.0175
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0277 0.0042 0.0366
Loa Loa (eye worm) hypothetical protein 0.026 0.0023 0.0026
Entamoeba histolytica PH domain containing protein kinase, putative 0.0841 0.0649 0.5781
Entamoeba histolytica tyrosine kinase, putative 0.026 0.0023 0.0175
Trichomonas vaginalis STE family protein kinase 0.0279 0.0044 0.0344
Leishmania major casein kinase, putative 0.0645 0.0439 0.0707
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0484 0.0265 0.0426
Loa Loa (eye worm) TKL/LRRK protein kinase 0.0478 0.0259 0.0333
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0372 0.0144 0.0144
Loa Loa (eye worm) hypothetical protein 0.0332 0.0101 0.0127
Brugia malayi Probable tyrosine-protein kinase kin-31 0.026 0.0023 0.0026
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.1104 0.0933 0.0933
Onchocerca volvulus 0.0488 0.027 0.0322
Brugia malayi Protein kinase domain containing protein 0.026 0.0023 0.0026
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.1278 0.1121 0.1817
Echinococcus multilocularis tyrosine protein kinase Fyn 0.1126 0.0957 0.0957
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.026 0.0023 0.0175
Trichomonas vaginalis CAMK family protein kinase 0.036 0.0132 0.1098
Trichomonas vaginalis TKL family protein kinase 0.026 0.0023 0.0168
Brugia malayi Immunoglobulin I-set domain containing protein 0.0295 0.0062 0.0076
Entamoeba histolytica protein kinase, putative 0.0699 0.0496 0.4412
Trichomonas vaginalis serine/threonine-protein kinase wnk, putative 0.026 0.0023 0.0168
Loa Loa (eye worm) AGC/PKA protein kinase 0.0794 0.0599 0.0775
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0754 0.0557 0.072
Schistosoma mansoni serine/threonine protein kinase 0.0341 0.0111 0.0269
Trichomonas vaginalis TKL family protein kinase 0.026 0.0023 0.0168
Echinococcus multilocularis serine:threonine protein kinase N2 0.0571 0.0358 0.0358
Schistosoma mansoni protein kinase 0.2543 0.2484 0.6207
Echinococcus multilocularis fibroblast growth factor receptor 4 0.1499 0.1359 0.1359
Echinococcus multilocularis cyclin dependent kinase 7 0.0651 0.0445 0.0445
Echinococcus granulosus serine:threonine protein kinase N2 0.1788 0.1671 0.2711
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.1008 0.083 0.1076
Brugia malayi Tyrosine-protein kinase abl-1 0.1411 0.1265 0.1641
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.026 0.0023 0.0032
Loa Loa (eye worm) hypothetical protein 0.0786 0.0591 0.0765
Trichomonas vaginalis CAMK family protein kinase 0.0372 0.0144 0.1202
Brugia malayi Protein kinase domain containing protein 0.0359 0.013 0.0164
Entamoeba histolytica casein kinase 1, putative 0.0645 0.0439 0.3894
Entamoeba histolytica protein kinase domain containing protein 0.026 0.0023 0.0175
Onchocerca volvulus 0.0352 0.0122 0.013
Echinococcus granulosus NCK adaptor protein 0.0409 0.0184 0.0293
Trichomonas vaginalis TKL family protein kinase 0.026 0.0023 0.0168
Entamoeba histolytica protein kinase domain containing protein 0.026 0.0023 0.0175
Brugia malayi Dual specificity mitogen-activated protein kinase kinase mek-2 0.1326 0.1172 0.1521
Plasmodium falciparum casein kinase 1 0.0645 0.0439 0.4131
Loa Loa (eye worm) CMGC/CDK/CDK9 protein kinase 0.0405 0.018 0.023
Brugia malayi Protein kinase domain containing protein 0.026 0.0023 0.0026
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.026 0.0023 0.0026
Loa Loa (eye worm) STE/STE7/MEK1 protein kinase 0.1326 0.1172 0.1521
Echinococcus multilocularis retinal guanylyl cyclase 2 0.026 0.0023 0.0023
Echinococcus granulosus glycogen synthase kinase 3 beta 0.1218 0.1057 0.1713
Echinococcus granulosus serine:threonine protein kinase 0.0341 0.011 0.0174
Leishmania major protein kinase, putative 0.0579 0.0367 0.0592
Onchocerca volvulus Slit protein homolog 0.0287 0.0053 0.0039
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.1278 0.1121 0.1454
Trichomonas vaginalis conserved hypothetical protein 0.026 0.0023 0.0168
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0295 0.0062 0.0076
Echinococcus granulosus Immunoglobulin 0.0662 0.0457 0.0738
Echinococcus multilocularis tyrosine protein kinase Fyn 0.1126 0.0957 0.0957
Loa Loa (eye worm) TK protein kinase 0.0946 0.0763 0.0988
Brugia malayi serine/threonine protein kinase 6 0.0639 0.0432 0.0558
Brugia malayi Immunoglobulin I-set domain containing protein 0.0699 0.0496 0.0642
Trichomonas vaginalis AGC family protein kinase 0.0745 0.0547 0.4647
Echinococcus multilocularis tyrosine protein kinase Srms 0.0946 0.0763 0.0763
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0803 0.0609 0.0984
Trichomonas vaginalis AGC family protein kinase 0.026 0.0023 0.0168
Loa Loa (eye worm) hypothetical protein 0.0948 0.0765 0.0992
Trichomonas vaginalis AGC family protein kinase 0.0745 0.0547 0.4647
Brugia malayi casein kinase I 0.0645 0.0439 0.0566
Schistosoma mansoni tyrosine kinase 0.026 0.0023 0.0049
Onchocerca volvulus Basement membrane proteoglycan homolog 0.0295 0.0062 0.005
Entamoeba histolytica leucine-rich repeat domain-containing protein 0.0263 0.0026 0.0206
Schistosoma mansoni serine/threonine kinase 0.0467 0.0247 0.0609
Entamoeba histolytica serine/threonine protein kinase, putative 0.0372 0.0144 0.1257
Entamoeba histolytica protein kinase domain containing protein 0.026 0.0023 0.0175
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0409 0.0184 0.0235
Loa Loa (eye worm) TK/DDR protein kinase 0.026 0.0023 0.0026
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.0341 0.011 0.0139
Echinococcus granulosus neuroglian 0.0332 0.0101 0.0158
Echinococcus multilocularis lachesin 0.0295 0.0062 0.0062
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.03 0.0066 0.0599
Trichomonas vaginalis CMGC family protein kinase 0.0484 0.0265 0.224
Loa Loa (eye worm) TK/FER protein kinase 0.0488 0.027 0.0347
Entamoeba histolytica tyrosine kinase, putative 0.026 0.0023 0.0175
Plasmodium falciparum calcium-dependent protein kinase 4 0.0579 0.0367 0.3456
Schistosoma mansoni neuroglian 0.0332 0.0101 0.0243
Trichomonas vaginalis TKL family protein kinase 0.026 0.0023 0.0168
Echinococcus granulosus ephrin type A receptor 4 A 0.0326 0.0094 0.0148
Trypanosoma brucei protein kinase, putative 0.1218 0.1057 0.1713
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.026 0.0023 0.0175
Trichomonas vaginalis CAMK family protein kinase 0.0372 0.0144 0.1202
Echinococcus granulosus cyclin dependent kinase 7 0.0651 0.0445 0.0719
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0277 0.0042 0.0042
Loa Loa (eye worm) AUR protein kinase 0.0639 0.0432 0.0558
Plasmodium falciparum serine/threonine protein kinase, putative 0.0639 0.0432 0.4069
Giardia lamblia Kinase, CAMK CAMKL 0.0413 0.0188 0.1579
Loa Loa (eye worm) hypothetical protein 0.0312 0.008 0.01
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.15 0.1361 0.1766
Onchocerca volvulus 0.0353 0.0124 0.0132
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.0282 0.0047 0.0071
Echinococcus multilocularis casein kinase I alpha 0.0645 0.0439 0.0439
Echinococcus multilocularis mitogen activated protein kinase 11 0.5947 0.6154 0.6154
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.3062 0.3044 0.3956
Echinococcus granulosus dual specificity protein kinase clk2 0.1112 0.0942 0.1526
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0699 0.0496 0.0642
Loa Loa (eye worm) hypothetical protein 0.1432 0.1287 0.167
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0426 0.0202 0.0259
Schistosoma mansoni protein kinase 0.1326 0.1172 0.2924
Echinococcus granulosus tyrosine protein kinase Blk 0.0946 0.0763 0.1234
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0288 0.0053 0.0081
Echinococcus multilocularis NCK adaptor protein 0.0426 0.0202 0.0202
Echinococcus multilocularis retinal guanylyl cyclase 2 0.026 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0295 0.0062 0.0076
Loa Loa (eye worm) hypothetical protein 0.1106 0.0936 0.1213
Schistosoma mansoni protein kinase 0.1705 0.1581 0.3946
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.1218 0.1057 0.2635
Trypanosoma brucei protein kinase, putative 0.0431 0.0208 0.0333
Schistosoma mansoni protein kinase 0.2543 0.2484 0.6207
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.1648 0.152 0.1973
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.2077 0.1982 0.2574
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.2334 0.2259 0.2917
Brugia malayi hypothetical protein 0.026 0.0023 0.0026
Giardia lamblia Kinase, CAMK CAMKL 0.0413 0.0188 0.1579
Giardia lamblia Kinase 0.026 0.0023 0.0168
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0277 0.0041 0.0041
Brugia malayi Protein kinase domain containing protein 0.0341 0.011 0.0139
Brugia malayi protein-tyrosine kinase 0.0946 0.0763 0.0988
Trichomonas vaginalis TKL family protein kinase 0.026 0.0023 0.0168
Echinococcus multilocularis rho associated protein kinase 0.0784 0.0588 0.0588
Echinococcus multilocularis protein KINase family member (kin 25) 0.0858 0.0669 0.0669
Schistosoma mansoni tyrosine kinase 0.2203 0.2118 0.5289
Entamoeba histolytica protein kinase, putative 0.039 0.0163 0.1432
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0775 0.0578 0.0578
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0579 0.0367 0.3456
Echinococcus multilocularis tyrosine protein kinase Blk 0.0946 0.0763 0.0763
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0295 0.0062 0.0076
Echinococcus granulosus TGF-beta receptor type-1 0.0921 0.0736 0.119
Entamoeba histolytica serine/threonine kinase, putative 0.026 0.0023 0.0175
Trichomonas vaginalis CAMK family protein kinase 0.0372 0.0144 0.1202
Loa Loa (eye worm) hypothetical protein 0.072 0.0519 0.0671
Schistosoma mansoni serine/threonine protein kinase 0.0571 0.0358 0.0888
Trichomonas vaginalis CAMK family protein kinase 0.032 0.0088 0.0721
Entamoeba histolytica protein kinase 2, putative 0.03 0.0066 0.0565
Loa Loa (eye worm) hypothetical protein 0.1106 0.0936 0.1213
Trichomonas vaginalis CAMK family protein kinase 0.0372 0.0144 0.1202
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.03 0.0066 0.0066
Loa Loa (eye worm) TK/KIN16 protein kinase 0.3684 0.3714 0.4829
Schistosoma mansoni tyrosine kinase 0.026 0.0023 0.0049
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.026 0.0023 0.0175
Loa Loa (eye worm) RGC/RGC protein kinase 0.026 0.0023 0.0026
Trichomonas vaginalis AGC family protein kinase 0.0639 0.0432 0.3667
Brugia malayi SH2 domain containing protein 0.0488 0.027 0.0347
Brugia malayi Protein kinase domain containing protein 0.0426 0.0203 0.0259
Entamoeba histolytica hypothetical protein 0.026 0.0023 0.0175
Trichomonas vaginalis CMGC family protein kinase 0.0484 0.0265 0.224
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.1278 0.1121 0.1817
Trichomonas vaginalis protein kinase atn1, putative 0.026 0.0023 0.0168
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.026 0.0023 0.0032
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0408 0.0183 0.0233
Echinococcus multilocularis dual specificity mitogen activated protein 0.1326 0.1172 0.1172
Loa Loa (eye worm) hypothetical protein 0.0958 0.0776 0.1005
Trichomonas vaginalis TKL family protein kinase 0.026 0.0023 0.0168
Schistosoma mansoni protein kinase 0.1008 0.083 0.2068
Trichomonas vaginalis TKL family protein kinase 0.026 0.0023 0.0168
Echinococcus granulosus tyrosine protein kinase HCK 0.0717 0.0516 0.0833
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0332 0.0101 0.0101
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0431 0.0208 0.0333
Brugia malayi Immunoglobulin I-set domain containing protein 0.0332 0.0101 0.0127
Entamoeba histolytica cell division protein kinase 2, putative 0.0484 0.0265 0.2342
Trichomonas vaginalis protein tyrosine kinase, putative 0.026 0.0023 0.0168
Giardia lamblia Kinase, AGC PKA 0.0794 0.0599 0.5098
Echinococcus granulosus serine:threonine protein kinase MARK2 0.051 0.0293 0.0471
Entamoeba histolytica protein kinase domain containing protein 0.0308 0.0076 0.0646
Schistosoma mansoni serine/threonine protein kinase 0.032 0.0088 0.0211
Loa Loa (eye worm) CMGC/CLK protein kinase 0.1112 0.0942 0.1222
Echinococcus granulosus atrial natriuretic peptide receptor 1 0.026 0.0023 0.0032
Brugia malayi Protein kinase domain containing protein 0.737 0.7689 1
Trichomonas vaginalis TKL family protein kinase 0.026 0.0023 0.0168
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0622 0.0414 0.0668
Brugia malayi Serine/threonine-protein kinase SULU 0.2933 0.2905 0.3776
Brugia malayi STE20-like kinase MST 0.0404 0.0178 0.0228
Schistosoma mansoni serine/threonine protein kinase 0.0359 0.013 0.0316
Entamoeba histolytica protein kinase, putative 0.026 0.0023 0.0175
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0332 0.0101 0.0101
Echinococcus multilocularis casein kinase I alpha 0.0645 0.0439 0.0439
Brugia malayi Furin-like cysteine rich region family protein 0.1054 0.088 0.1141
Loa Loa (eye worm) hypothetical protein 0.0861 0.0671 0.0869
Trichomonas vaginalis TKL family protein kinase 0.026 0.0023 0.0168
Echinococcus granulosus tyrosine protein kinase csk 0.026 0.0023 0.0032
Trypanosoma brucei aurora B kinase 0.0639 0.0432 0.0697
Brugia malayi Immunoglobulin I-set domain containing protein 0.0295 0.0062 0.0076
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.1472 0.133 0.133
Loa Loa (eye worm) protein kinase domain-containing protein 0.026 0.0023 0.0026
Trichomonas vaginalis TKL family protein kinase 0.026 0.0023 0.0168
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0579 0.0367 0.0592
Echinococcus multilocularis dual specificity 0.1278 0.1121 0.1121
Entamoeba histolytica protein kinase domain containing protein 0.026 0.0023 0.0175
Entamoeba histolytica serine/threonine kinase, putative 0.026 0.0023 0.0175
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.1075 0.0902 0.0902
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0346 0.0116 0.0146
Plasmodium falciparum NIMA related kinase 1 0.0279 0.0044 0.0382
Onchocerca volvulus 0.1218 0.1057 0.1349
Loa Loa (eye worm) AGC/AKT protein kinase 0.0745 0.0547 0.0707
Trichomonas vaginalis TKL family protein kinase 0.026 0.0023 0.0168
Entamoeba histolytica hypothetical protein 0.0262 0.0026 0.0199
Trichomonas vaginalis AGC family protein kinase 0.0745 0.0547 0.4647
Schistosoma mansoni tyrosine kinase 0.0858 0.0669 0.1664
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0639 0.0432 0.0432
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0332 0.0101 0.0101
Loa Loa (eye worm) hypothetical protein 0.0958 0.0776 0.1005
Plasmodium vivax calcium-dependent protein kinase, putative 0.0579 0.0367 0.3456
Echinococcus granulosus phosphorylase kinase gamma subunit 0.0308 0.0075 0.0116
Schistosoma mansoni protein kinase 0.0645 0.0439 0.1089
Entamoeba histolytica protein kinase, putative 0.1218 0.1057 0.9425
Schistosoma mansoni serine/threonine protein kinase 0.0308 0.0075 0.0179
Loa Loa (eye worm) hypothetical protein 0.026 0.0023 0.0026
Brugia malayi Probable tyrosine-protein kinase kin-31 0.026 0.0023 0.0026
Brugia malayi Immunoglobulin I-set domain containing protein 0.0487 0.0268 0.0344
Brugia malayi Protein kinase domain containing protein 0.0571 0.0358 0.0462
Schistosoma mansoni serine/threonine protein kinase 0.0651 0.0445 0.1106
Trypanosoma cruzi cdc2-related kinase 1 0.0484 0.0265 0.0426
Onchocerca volvulus Tyrosine kinase homolog 0.3125 0.3112 0.403
Toxoplasma gondii AGC kinase 0.0699 0.0496 0.4681
Loa Loa (eye worm) hypothetical protein 0.0579 0.0367 0.0474
Loa Loa (eye worm) hypothetical protein 0.0861 0.0671 0.0869
Loa Loa (eye worm) hypothetical protein 0.0759 0.0562 0.0726
Loa Loa (eye worm) TK/CSK protein kinase 0.026 0.0023 0.0026
Echinococcus granulosus activated cdc42 kinase 1 0.1815 0.17 0.2758
Loa Loa (eye worm) TK/FER protein kinase 0.0488 0.027 0.0347
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0639 0.0432 0.3835
Schistosoma mansoni tyrosine kinase 0.2309 0.2233 0.5577
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.026 0.0023 0.0175
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0409 0.0184 0.0451
Echinococcus granulosus retinal guanylyl cyclase 2 0.026 0.0023 0.0032
Brugia malayi Protein kinase domain containing protein 0.026 0.0023 0.0026
Loa Loa (eye worm) TK/FER protein kinase 0.0488 0.027 0.0347
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.1218 0.1057 1
Loa Loa (eye worm) hypothetical protein 0.0295 0.0062 0.0076
Giardia lamblia Kinase, CMGC CDK 0.0484 0.0265 0.224
Brugia malayi P38 map kinase family protein 2 0.5947 0.6154 0.8003
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0703 0.0501 0.0501
Entamoeba histolytica protein kinase domain containing protein 0.026 0.0023 0.0175
Schistosoma mansoni serine/threonine protein kinase 0.1104 0.0933 0.2325
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0794 0.0599 0.0599
Echinococcus granulosus epidermal growth factor receptor 0.1054 0.088 0.1425
Schistosoma mansoni protein kinase 0.0367 0.0139 0.034
Echinococcus multilocularis cyclin dependent kinase 1 0.0484 0.0265 0.0265
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0332 0.0101 0.0127
Trichomonas vaginalis TKL family protein kinase 0.026 0.0023 0.0168
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0794 0.0599 0.0969
Schistosoma mansoni growth factor receptor-bound protein 0.0426 0.0202 0.0497
Schistosoma mansoni protein kinase 0.026 0.0023 0.0049
Trichomonas vaginalis conserved hypothetical protein 0.026 0.0023 0.0168
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.0282 0.0047 0.0056
Loa Loa (eye worm) hypothetical protein 0.0662 0.0457 0.0591
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.026 0.0023 0.0175
Entamoeba histolytica hypothetical protein 0.026 0.0023 0.0175
Loa Loa (eye worm) thyroid receptor interactor 0.0858 0.0668 0.0865
Trichomonas vaginalis CAMK family protein kinase 0.032 0.0088 0.0721
Echinococcus multilocularis calcium activated potassium channel 0.0341 0.0111 0.0111
Brugia malayi Protein kinase domain containing protein 0.2334 0.2259 0.2935
Brugia malayi Protein kinase domain containing protein 0.1436 0.1291 0.1676
Trichomonas vaginalis CMGC family protein kinase 0.1112 0.0942 0.8031
Schistosoma mansoni serine/threonine RGC 0.026 0.0023 0.0049
Trichomonas vaginalis conserved hypothetical protein 0.026 0.0023 0.0168
Echinococcus multilocularis tyrosine protein kinase Fgr 0.1126 0.0957 0.0957
Echinococcus granulosus growth factor receptor bound protein 2 0.0426 0.0202 0.0323
Trichomonas vaginalis CMGC family protein kinase 0.0282 0.0047 0.0371
Entamoeba histolytica protein kinase, putative 0.026 0.0023 0.0175
Entamoeba histolytica protein kinase, putative 0.0745 0.0547 0.486
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0277 0.0042 0.0042
Schistosoma mansoni serine/threonine protein kinase 0.0734 0.0534 0.1328
Onchocerca volvulus 0.0786 0.0591 0.0741
Entamoeba histolytica protein kinase, putative 0.0639 0.0432 0.3835
Loa Loa (eye worm) AGC/PKG protein kinase 0.0277 0.0042 0.005
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.0282 0.0047 0.0412
Echinococcus multilocularis casein kinase I gamma 0.0359 0.013 0.013
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.026 0.0023 0.0049
Loa Loa (eye worm) CAMK/PKD protein kinase 0.112 0.0951 0.1233
Schistosoma mansoni protein kinase 0.0337 0.0107 0.0259
Entamoeba histolytica tyrosine kinase, putative 0.026 0.0023 0.0175
Leishmania major mitogen-activated protein kinase kinase 5, putative;with=GeneDB:LmxM36.0860 0.1326 0.1172 0.19
Loa Loa (eye worm) hypothetical protein 0.072 0.0519 0.0671
Brugia malayi protein kinase C3,putative 0.042 0.0195 0.025
Echinococcus multilocularis roundabout 2 0.0332 0.0101 0.0101
Trichomonas vaginalis CAMK family protein kinase 0.032 0.0088 0.0721
Echinococcus multilocularis insulin receptor 0.1436 0.1291 0.1291
Plasmodium falciparum protein serine/threonine kinase-1 0.1112 0.0942 0.8912
Giardia lamblia Kinase, AGC PKA 0.03 0.0066 0.054
Echinococcus granulosus roundabout 2 0.0332 0.0101 0.0158
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0484 0.0265 0.0341
Trypanosoma cruzi polo-like protein kinase, putative 0.032 0.0088 0.0137
Echinococcus granulosus c-Jun N-terminal kinases 0.3062 0.3044 0.4943
Entamoeba histolytica protein kinase, putative 0.0263 0.0026 0.0206
Schistosoma mansoni vam6/vps39 related 0.072 0.0519 0.129
Brugia malayi Hr1 repeat family protein 0.1788 0.1671 0.2169
Brugia malayi serine/threonine-protein kinase plk-2 0.032 0.0088 0.011
Schistosoma mansoni serine/threonine protein kinase 0.0372 0.0144 0.0351
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0319 0.0088 0.0109
Trypanosoma brucei cdc2-related kinase 3 0.0484 0.0265 0.0426
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0803 0.0609 0.0609
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.039 0.0163 0.026
Trichomonas vaginalis TKL family protein kinase 0.026 0.0023 0.0168
Entamoeba histolytica protein kinase domain containing protein 0.026 0.0023 0.0175
Brugia malayi Protein kinase domain containing protein 0.026 0.0023 0.0026
Echinococcus multilocularis Immunoglobulin 0.0662 0.0457 0.0457
Giardia lamblia Kinase, CMGC GSK 0.1218 0.1057 0.9011
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.1126 0.0957 0.155
Loa Loa (eye worm) CAMK/PIM protein kinase 0.2334 0.2259 0.2935
Echinococcus multilocularis homeodomain interacting protein kinase 3 0.0348 0.0118 0.0118
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0794 0.0599 0.0969
Loa Loa (eye worm) TK/FER protein kinase 0.026 0.0023 0.0026
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0484 0.0265 0.0426
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0794 0.0599 0.0969
Schistosoma mansoni tyrosine kinase 0.0455 0.0234 0.0576
Schistosoma mansoni serine/threonine protein kinase 0.1788 0.1671 0.4171
Loa Loa (eye worm) CMGC/DYRK/HIPK protein kinase 0.0348 0.0118 0.0149
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.026 0.0023 0.0175
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0413 0.0188 0.1752
Entamoeba histolytica protein kinase domain containing protein 0.0431 0.0208 0.1833
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.026 0.0023 0.0049
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0579 0.0367 0.3456
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.5947 0.6154 1
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0571 0.0358 0.0577
Trichomonas vaginalis TKL family protein kinase 0.026 0.0023 0.0168
Schistosoma mansoni tyrosine kinase 0.0668 0.0464 0.1151
Trichomonas vaginalis TKL family protein kinase 0.026 0.0023 0.0168
Echinococcus granulosus activin receptor type 0.4255 0.4331 0.7035
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0645 0.0439 0.0707
Echinococcus multilocularis cyclin dependent kinase 1 0.0484 0.0265 0.0265
Echinococcus granulosus serine:threonine protein kinase TAO1 0.2933 0.2905 0.4718
Echinococcus granulosus TGF beta receptor type 1 0.0921 0.0736 0.119
Echinococcus granulosus tyrosine protein kinase Src42A 0.1126 0.0957 0.155
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.1446 0.1302 0.2111
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.026 0.0023 0.0175
Trichomonas vaginalis CAMK family protein kinase 0.0257 0.002 0.0143
Entamoeba histolytica protein kinase domain containing protein 0.026 0.0023 0.0175
Brugia malayi Immunoglobulin I-set domain containing protein 0.0332 0.0101 0.0127
Schistosoma mansoni protein kinase 0.026 0.0023 0.0049
Leishmania major protein kinase, putative 0.1112 0.0942 0.1526
Plasmodium falciparum protein kinase, putative 0.0431 0.0208 0.1945
Entamoeba histolytica receptor protein kinase, putative 0.026 0.0023 0.0175
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.03 0.0066 0.0599
Entamoeba histolytica protein kinase, putative 0.1278 0.1121 1
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.026 0.0023 0.0186
Plasmodium falciparum protein kinase, putative 0.026 0.0023 0.0186
Entamoeba histolytica protein kinase, putative 0.026 0.0023 0.0175
Entamoeba histolytica hypothetical protein 0.0263 0.0026 0.0206
Giardia lamblia Kinase, NEK 0.0279 0.0044 0.0344
Trichomonas vaginalis TKL family protein kinase 0.026 0.0023 0.0168
Brugia malayi map kinase activated protein kinase protein 2 0.0546 0.0332 0.0427
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.2507 0.2446 0.2446
Giardia lamblia Kinase, NEK 0.0279 0.0044 0.0344
Trichomonas vaginalis TKL family protein kinase 0.026 0.0023 0.0168
Entamoeba histolytica ankyrin repeat protein 0.026 0.0023 0.0175
Echinococcus granulosus protein tyrosine kinase 0.3949 0.4001 0.6499
Schistosoma mansoni tyrosine kinase 0.026 0.0023 0.0049
Entamoeba histolytica hypothetical protein 0.1278 0.1121 1
Onchocerca volvulus 0.0948 0.0765 0.0969
Brugia malayi Protein kinase domain containing protein 0.0759 0.0562 0.0726
Trichomonas vaginalis TKL family protein kinase 0.026 0.0023 0.0168
Schistosoma mansoni tyrosine kinase 0.0651 0.0445 0.1105
Trypanosoma brucei rac serine-threonine kinase, putative 0.0745 0.0547 0.0883
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0401 0.0175 0.1536
Loa Loa (eye worm) hypothetical protein 0.0666 0.0461 0.0595
Loa Loa (eye worm) hypothetical protein 0.0662 0.0457 0.0591
Brugia malayi serine/threonine-protein kinase 6 0.0639 0.0432 0.0558
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0579 0.0367 0.0474
Trichomonas vaginalis STE family protein kinase 0.0367 0.0139 0.1162
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0391 0.0164 0.0403
Schistosoma mansoni serine/threonine protein kinase 0.1446 0.1302 0.3248
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0288 0.0053 0.0053
Brugia malayi Immunoglobulin I-set domain containing protein 0.0295 0.0062 0.0076
Entamoeba histolytica protein kinase, putative 0.026 0.0023 0.0175
Entamoeba histolytica hypothetical protein, conserved 0.026 0.0023 0.0175
Echinococcus granulosus rho-associated protein kinase 1 0.0784 0.0588 0.0951
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.0282 0.0047 0.0056
Schistosoma mansoni nephrin 0.0898 0.0712 0.1772
Echinococcus granulosus protein kinase 0.026 0.0023 0.0032
Echinococcus granulosus tyrosine protein kinase Fyn 0.1126 0.0957 0.155
Echinococcus multilocularis casein kinase i 0.0645 0.0439 0.0439
Echinococcus granulosus N chimaerin 0.0391 0.0164 0.0262
Trichomonas vaginalis CMGC family protein kinase 0.0484 0.0265 0.224
Plasmodium falciparum protein kinase 5 0.0484 0.0265 0.2485
Trypanosoma brucei Flagellum attachment zone protein 20 0.026 0.0023 0.0032
Schistosoma mansoni ephrin receptor 0.0326 0.0094 0.0228
Trichomonas vaginalis TKL family protein kinase 0.026 0.0023 0.0168
Trypanosoma cruzi polo-like protein kinase, putative 0.032 0.0088 0.0137
Echinococcus multilocularis protein kinase 0.026 0.0023 0.0023
Entamoeba histolytica protein kinase domain containing protein 0.026 0.0023 0.0175
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0484 0.0265 0.0341
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0459 0.0238 0.0238
Echinococcus granulosus protein kinase c iota type 0.0818 0.0625 0.1011
Entamoeba histolytica hypothetical protein 0.0263 0.0026 0.0206
Trichomonas vaginalis CAMK family protein kinase 0.0372 0.0144 0.1202
Schistosoma mansoni tyrosine kinase 0.0911 0.0725 0.1805
Trichomonas vaginalis CK1 family protein kinase 0.0645 0.0439 0.3723
Schistosoma mansoni serine/threonine protein kinase 0.0348 0.0118 0.0286
Schistosoma mansoni atypical protein kinase C 0.0825 0.0632 0.1573
Schistosoma mansoni serine/threonine protein kinase 0.0579 0.0367 0.0911
Schistosoma mansoni protein kinase 0.039 0.0163 0.04
Entamoeba histolytica protein kinase domain containing protein 0.026 0.0023 0.0175
Trypanosoma cruzi cdc2-related kinase 3 0.0484 0.0265 0.0426
Trypanosoma brucei Pseudokinase, putative 0.026 0.0023 0.0032
Giardia lamblia Kinase, CMGC CDK 0.0484 0.0265 0.224
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.5947 0.6154 1
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0391 0.0164 0.0403
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0758 0.0561 0.0906
Entamoeba histolytica protein kinase, putative 0.026 0.0023 0.0175
Entamoeba histolytica protein kinase with ankyrin repeats, putative 0.026 0.0023 0.0175
Echinococcus multilocularis heat shock protein 70 0.026 0.0023 0.0023
Entamoeba histolytica protein kinase domain containing protein 0.026 0.0023 0.0175
Entamoeba histolytica hypothetical protein 0.0394 0.0168 0.1469
Leishmania major protein kinase A catalytic subunit 0.0794 0.0599 0.0969
Echinococcus multilocularis serine threonine protein kinase 0.0613 0.0404 0.0404
Entamoeba histolytica tyrosine kinase, putative 0.026 0.0023 0.0175
Trichomonas vaginalis TKL family protein kinase 0.026 0.0023 0.0168
Brugia malayi integrin-linked kinase 0.026 0.0023 0.0026
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.072 0.0519 0.0838
Schistosoma mansoni serine/threonine protein kinase 0.0341 0.0111 0.0269
Echinococcus granulosus casein kinase I alpha 0.0645 0.0439 0.0707
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.2285 0.2206 0.2866
Giardia lamblia Aurora kinase 0.0639 0.0432 0.3667
Echinococcus granulosus tyrosine protein kinase ABL1 0.2432 0.2364 0.3839
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0571 0.0358 0.0358
Schistosoma mansoni protein kinase 0.0431 0.0208 0.0512
Echinococcus multilocularis roundabout 2 0.0332 0.0101 0.0101
Trichomonas vaginalis CAMK family protein kinase 0.0372 0.0144 0.1202
Echinococcus multilocularis neuroglian 0.0332 0.0101 0.0101
Entamoeba histolytica protein kinase, putative 0.0639 0.0432 0.3835
Trichomonas vaginalis AGC family protein kinase 0.0612 0.0402 0.3413
Echinococcus granulosus tyrosine protein kinase csk 0.026 0.0023 0.0032
Echinococcus granulosus insulin growth factor 1 receptor beta 0.1472 0.133 0.2157
Onchocerca volvulus 0.2666 0.2617 0.3384
Trichomonas vaginalis AGC family protein kinase 0.0263 0.0027 0.0199
Echinococcus granulosus casein kinase I alpha 0.0645 0.0439 0.0707
Schistosoma mansoni serine/threonine protein kinase 0.0277 0.0042 0.0096
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.051 0.0293 0.0293
Entamoeba histolytica tyrosine kinase, putative 0.026 0.0023 0.0175
Trichomonas vaginalis TKL family protein kinase 0.026 0.0023 0.0168
Giardia lamblia Kinase, CMGC GSK 0.1218 0.1057 0.9011
Echinococcus multilocularis hemicentin 1 0.0295 0.0062 0.0062
Brugia malayi Variant SH3 domain containing protein 0.0409 0.0184 0.0235
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0759 0.0562 0.0726
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0372 0.0144 0.0183
Loa Loa (eye worm) RGC/RGC protein kinase 0.026 0.0023 0.0026
Entamoeba histolytica hypothetical protein 0.026 0.0023 0.0175
Entamoeba histolytica tyrosine kinase, putative 0.026 0.0023 0.0175
Schistosoma mansoni serine/threonine protein kinase 0.0421 0.0197 0.0486
Entamoeba histolytica tyrosine kinase, putative 0.026 0.0023 0.0175
Trichomonas vaginalis TKL family protein kinase 0.026 0.0023 0.0168
Brugia malayi Protein kinase domain containing protein 0.1815 0.17 0.2207
Brugia malayi Immunoglobulin I-set domain containing protein 0.0295 0.0062 0.0076
Schistosoma mansoni protein kinase 0.0431 0.0208 0.0512
Echinococcus granulosus dual specificity 0.0282 0.0047 0.0071
Entamoeba histolytica protein kinase, putative 0.026 0.0023 0.0175
Entamoeba histolytica protein kinase, putative 0.0401 0.0175 0.1536
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0282 0.0047 0.0071
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.2933 0.2905 0.2905
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0579 0.0367 0.3456
Toxoplasma gondii STE kinase 0.026 0.0023 0.0186
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0668 0.0464 0.1151
Loa Loa (eye worm) hypothetical protein 0.0861 0.0671 0.0869
Trichomonas vaginalis AGC family protein kinase 0.0571 0.0358 0.3036
Schistosoma mansoni tyrosine kinase 0.1436 0.1291 0.3221
Giardia lamblia Kinase, AGC AKT 0.1047 0.0872 0.7429
Brugia malayi Protein kinase domain containing protein 0.0759 0.0562 0.0726
Trichomonas vaginalis TKL family protein kinase 0.026 0.0023 0.0168
Loa Loa (eye worm) hypothetical protein 0.1815 0.17 0.2207
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.072 0.0519 0.129
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.032 0.0088 0.0137
Schistosoma mansoni tyrosine kinase 0.026 0.0023 0.0049
Echinococcus granulosus defective proboscis extension response 0.0662 0.0457 0.0738
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0579 0.0367 0.0474
Loa Loa (eye worm) hypothetical protein 0.0599 0.0389 0.0501
Echinococcus multilocularis beta adrenergic receptor kinase 0.0319 0.0088 0.0088
Trichomonas vaginalis TKL family protein kinase 0.026 0.0023 0.0168
Brugia malayi Guanylyl cyclase protein 23 0.026 0.0023 0.0026
Trichomonas vaginalis TKL family protein kinase 0.026 0.0023 0.0168
Entamoeba histolytica casein kinase, putative 0.0645 0.0439 0.3894
Echinococcus multilocularis tyrosine protein kinase csk 0.026 0.0023 0.0023
Schistosoma mansoni serine/threonine protein kinase 0.026 0.0023 0.0049
Schistosoma mansoni serine/threonine protein kinase 0.1278 0.1121 0.2796
Schistosoma mansoni tyrosine kinase 0.026 0.0023 0.0049
Echinococcus multilocularis tyrosine protein kinase Src64B 0.1126 0.0957 0.0957
Echinococcus multilocularis PAK box P21 Rho binding 0.0367 0.0139 0.0139
Schistosoma mansoni tyrosine kinase 0.026 0.0023 0.0049
Trypanosoma cruzi casein kinase, putative 0.0645 0.0439 0.0707
Trichomonas vaginalis CAMK family protein kinase 0.032 0.0088 0.0721
Loa Loa (eye worm) TKL/RAF/KSR protein kinase 0.026 0.0023 0.0026
Trichomonas vaginalis CAMK family protein kinase 0.0372 0.0144 0.1202
Entamoeba histolytica tyrosine kinase, putative 0.026 0.0023 0.0175
Trichomonas vaginalis TKL family protein kinase 0.026 0.0023 0.0168
Schistosoma mansoni tyrosine kinase 0.0911 0.0725 0.1805
Plasmodium falciparum serine/threonine protein kinase KIN 0.0372 0.0144 0.1334
Entamoeba histolytica protein kinase domain containing protein 0.1218 0.1057 0.9425
Echinococcus multilocularis serine:threonine protein kinase 3 0.0404 0.0178 0.0178
Trypanosoma cruzi mitogen-activated protein kinase kinase 5 0.1326 0.1172 0.19
Echinococcus granulosus receptor type guanylyl cyclase 0.026 0.0023 0.0032
Schistosoma mansoni serine/threonine protein kinase 0.0277 0.0042 0.0096
Echinococcus multilocularis epidermal growth factor receptor 0.0911 0.0725 0.0725
Entamoeba histolytica protein kinase, putative 0.0571 0.0358 0.3176
Giardia lamblia Kinase, CK1 Casein kinase 0.0645 0.0439 0.3723
Trichomonas vaginalis TKL family protein kinase 0.026 0.0023 0.0168
Trypanosoma brucei cdc2-related kinase 1 0.0484 0.0265 0.0426
Echinococcus multilocularis tyrosine kinase 0.0488 0.027 0.027
Entamoeba histolytica serine/threonine kinase, putative 0.026 0.0023 0.0175
Entamoeba histolytica serine/threonine kinase, putative 0.026 0.0023 0.0175
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.051 0.0293 0.0293
Entamoeba histolytica protein kinase, putative 0.026 0.0023 0.0175
Schistosoma mansoni serine/threonine protein kinase 0.0639 0.0432 0.1072
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.15 0.1361 0.1766
Schistosoma mansoni tyrosine kinase 0.026 0.0023 0.0049
Echinococcus granulosus tyrosine kinase 0.0946 0.0763 0.1234
Echinococcus multilocularis Immunoglobulin 0.0662 0.0457 0.0457
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0372 0.0144 0.0228
Loa Loa (eye worm) AUR protein kinase 0.0639 0.0432 0.0558
Schistosoma mansoni serine/threonine-protein kinase 0.0346 0.0117 0.0283
Brugia malayi hypothetical protein 0.026 0.0023 0.0026
Trichomonas vaginalis TKL family protein kinase 0.026 0.0023 0.0168
Trichomonas vaginalis TKL family protein kinase 0.026 0.0023 0.0168
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.039 0.0163 0.026
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.5745 0.5937 0.9646
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0734 0.0534 0.0691
Trypanosoma brucei mitogen-activated protein kinase kinase 5 0.1326 0.1172 0.19
Trichomonas vaginalis STE family protein kinase 0.039 0.0163 0.1369
Echinococcus multilocularis cyclin dependent kinase 9 0.0446 0.0224 0.0224
Echinococcus multilocularis expressed conserved protein 0.0277 0.0042 0.0042
Schistosoma mansoni serine/threonine protein kinase 0.1104 0.0933 0.2325
Echinococcus granulosus retinal guanylyl cyclase 2 0.026 0.0023 0.0032
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.1964 0.186 0.2416
Schistosoma mansoni ste20-related kinase 0.035 0.0121 0.0293
Entamoeba histolytica protein kinase, putative 0.026 0.0023 0.0175
Brugia malayi Receptor family ligand binding region containing protein 0.026 0.0023 0.0026
Trypanosoma cruzi casein kinase, putative 0.0645 0.0439 0.0707
Entamoeba histolytica protein kinase, putative 0.0414 0.0189 0.1664
Echinococcus granulosus Vam6:Vps39 protein 0.072 0.0519 0.0838
Loa Loa (eye worm) hypothetical protein 0.0409 0.0184 0.0235
Echinococcus granulosus calcium activated potassium channel 0.0341 0.0111 0.0175
Trichomonas vaginalis TKL family protein kinase 0.026 0.0023 0.0168
Trichomonas vaginalis CAMK family protein kinase 0.0372 0.0144 0.1202
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.026 0.0023 0.0186
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.2507 0.2446 0.397
Trichomonas vaginalis TKL family protein kinase 0.026 0.0023 0.0168
Brugia malayi Protein kinase domain containing protein 0.1112 0.0942 0.1222
Echinococcus multilocularis mitogen activated protein kinase 14 0.5947 0.6154 0.6154
Echinococcus multilocularis serine:threonine protein kinase N2 0.1788 0.1671 0.1671
Loa Loa (eye worm) TKL/MLK/TAK1 protein kinase 0.026 0.0023 0.0026
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.1112 0.0942 0.8912
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.1648 0.152 0.1973
Echinococcus granulosus hemicentin 1 0.0295 0.0062 0.0095
Echinococcus multilocularis cyclin dependent kinase 0.0484 0.0265 0.0265
Trichomonas vaginalis CAMK family protein kinase 0.032 0.0088 0.0721
Echinococcus granulosus casein kinase I delta 0.0645 0.0439 0.0707
Entamoeba histolytica hypothetical protein 0.026 0.0023 0.0175
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0571 0.0358 0.0358
Toxoplasma gondii AGC kinase 0.0794 0.0599 0.5658
Loa Loa (eye worm) TK/ABL protein kinase 0.2432 0.2364 0.3072
Echinococcus granulosus tyrosine protein kinase Fes:Fps 0.026 0.0023 0.0032
Brugia malayi Protein kinase domain containing protein 0.5222 0.5373 0.6986
Brugia malayi Peroxidasin 0.0299 0.0065 0.008
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.1093 0.0922 0.1493
Trichomonas vaginalis TKL family protein kinase 0.026 0.0023 0.0168
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.039 0.0163 0.0163
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.1278 0.1121 0.1817
Brugia malayi cyclin-dependent kinase 9 0.0405 0.018 0.023
Loa Loa (eye worm) TK protein kinase 0.026 0.0023 0.0026
Trichomonas vaginalis TKL family protein kinase 0.026 0.0023 0.0168
Echinococcus granulosus titin 0.0408 0.0183 0.0292
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0579 0.0367 0.3456
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.1964 0.186 0.2416
Echinococcus multilocularis serine:threonine protein kinase 0.0341 0.011 0.011
Loa Loa (eye worm) TK protein kinase 0.026 0.0023 0.0026
Brugia malayi SH2 domain containing protein 0.0803 0.0609 0.0787
Schistosoma mansoni protein kinase 0.026 0.0023 0.0049
Trichomonas vaginalis conserved hypothetical protein 0.026 0.0023 0.0168
Loa Loa (eye worm) gastrulation defective protein 1 0.164 0.1511 0.1962
Echinococcus granulosus mitogen activated protein kinase 11 0.5947 0.6154 1
Entamoeba histolytica protein kinase , putative 0.0639 0.0432 0.3835
Trichomonas vaginalis AGC family protein kinase 0.0745 0.0547 0.4647
Entamoeba histolytica protein kinase, putative 0.058 0.0369 0.327
Echinococcus granulosus twitchin 0.1034 0.0858 0.1389
Loa Loa (eye worm) TK/EPH protein kinase 0.0344 0.0114 0.0144
Schistosoma mansoni serine/threonine protein kinase 0.0341 0.0111 0.0269
Loa Loa (eye worm) hypothetical protein 0.0488 0.027 0.0347
Brugia malayi Protein kinase domain containing protein 0.026 0.0023 0.0026
Echinococcus multilocularis cyclin dependent kinase 9 0.0405 0.018 0.018
Schistosoma mansoni serine/threonine protein kinase 0.0635 0.0428 0.1061
Echinococcus granulosus cyclin dependent kinase 9 0.0405 0.018 0.0287
Onchocerca volvulus 0.0612 0.0403 0.0496
Schistosoma mansoni serine/threonine protein kinase 0.2334 0.2259 0.5643
Loa Loa (eye worm) hypothetical protein 0.026 0.0023 0.0026
Entamoeba histolytica protein kinase domain containing protein 0.1278 0.1121 1
Toxoplasma gondii AGC kinase 0.0794 0.0599 0.5658
Trichomonas vaginalis TKL family protein kinase 0.026 0.0023 0.0168
Echinococcus granulosus MAP kinase activated protein kinase 2 0.0546 0.0332 0.0534
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0946 0.0763 0.1234
Brugia malayi Protein kinase domain containing protein 0.026 0.0023 0.0026
Entamoeba histolytica protein kinase, putative 0.0579 0.0367 0.3257
Entamoeba histolytica protein kinase domain containing protein 0.026 0.0023 0.0175
Loa Loa (eye worm) hypothetical protein 0.026 0.0023 0.0026
Brugia malayi Variant SH3 domain containing protein 0.0409 0.0184 0.0235
Trichomonas vaginalis TKL family protein kinase 0.0262 0.0026 0.0191
Trichomonas vaginalis CAMK family protein kinase 0.0426 0.0203 0.1705
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0263 0.0027 0.003
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.0404 0.0178 0.0228
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.0426 0.0203 0.0259
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0794 0.0599 0.0969
Schistosoma mansoni serine/threonine protein kinase 0.026 0.0023 0.0049
Brugia malayi Protein kinase domain containing protein 0.0478 0.0259 0.0333
Entamoeba histolytica protein kinase domain containing protein 0.026 0.0023 0.0175
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0488 0.027 0.2383
Trichomonas vaginalis TKL family protein kinase 0.026 0.0023 0.0168
Entamoeba histolytica protein kinase, putative 0.026 0.0023 0.0175
Echinococcus multilocularis tyrosine protein kinase Src42A 0.1126 0.0957 0.0957
Entamoeba histolytica tyrosine kinase, putative 0.026 0.0023 0.0175
Trichomonas vaginalis CAMK family protein kinase 0.0372 0.0144 0.1202
Schistosoma mansoni cell adhesion molecule 0.0295 0.0062 0.0146
Plasmodium vivax glycogen synthase kinase 3, putative 0.1218 0.1057 1
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.026 0.0023 0.0026
Echinococcus multilocularis dual specificity 0.0282 0.0047 0.0047
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0484 0.0265 0.2485
Toxoplasma gondii casein kinase I 0.0645 0.0439 0.4131
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.026 0.0023 0.0026
Echinococcus granulosus 3'partial|retinal guanylyl cyclase 2 0.026 0.0023 0.0032
Entamoeba histolytica serine/threonine kinase, putative 0.026 0.0023 0.0175
Schistosoma mansoni protein kinase 0.0639 0.0432 0.1072
Echinococcus multilocularis tyrosine kinase 0.026 0.0023 0.0023
Toxoplasma gondii protein kinase domain-containing protein 0.026 0.0023 0.0186
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.081 0.0617 0.0798
Entamoeba histolytica tyrosine- protein kinase 2, putative 0.026 0.0023 0.0175
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.0546 0.0332 0.0332
Loa Loa (eye worm) serine/threonine protein kinase 0.026 0.0023 0.0026
Brugia malayi Protein kinase domain containing protein 0.0745 0.0547 0.0707
Brugia malayi Protein kinase domain containing protein 0.0488 0.027 0.0347
Echinococcus granulosus tyrosine protein kinase 0.026 0.0023 0.0032
Onchocerca volvulus 0.0784 0.0588 0.0738
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0892 0.0704 0.1139
Schistosoma mansoni septate junction protein 0.0295 0.0062 0.0146
Entamoeba histolytica protein kinase, putative 0.0717 0.0516 0.4586
Schistosoma mansoni serine/threonine protein kinase 0.0546 0.0332 0.0822
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.0372 0.0144 0.0228
Trichomonas vaginalis conserved hypothetical protein 0.026 0.0023 0.0168
Trichomonas vaginalis serine-threonine protein kinase, putative 0.026 0.0023 0.0168
Loa Loa (eye worm) hypothetical protein 0.1023 0.0846 0.1096
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0858 0.0669 0.1081
Trypanosoma cruzi casein kinase, putative 0.0645 0.0439 0.0707
Trypanosoma brucei polo-like protein kinase 0.032 0.0088 0.0137
Echinococcus granulosus raf serine:threonine protein kinase 0.0421 0.0197 0.0316
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.026 0.0023 0.0168
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.1499 0.1359 0.2204
Echinococcus multilocularis N chimaerin 0.0391 0.0164 0.0164
Echinococcus granulosus Protein kinase C brain isozyme 0.0775 0.0578 0.0935
Trichomonas vaginalis TKL family protein kinase 0.026 0.0023 0.0168
Schistosoma mansoni protein kinase 0.0921 0.0736 0.1832
Loa Loa (eye worm) TK protein kinase 0.026 0.0023 0.0026
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0639 0.0432 0.3835
Entamoeba histolytica receptor protein kinase, putative 0.026 0.0023 0.0175
Brugia malayi Protein kinase domain containing protein 0.026 0.0023 0.0026
Schistosoma mansoni serine/threonine protein kinase 0.0651 0.0445 0.1106
Trypanosoma cruzi protein kinase, putative 0.026 0.0023 0.0032
Onchocerca volvulus 0.0284 0.0049 0.0034
Echinococcus multilocularis cyclin dependent kinase 5 0.0484 0.0265 0.0265
Echinococcus multilocularis twitchin 0.0371 0.0144 0.0144
Loa Loa (eye worm) TK/FER protein kinase 0.026 0.0023 0.0026
Entamoeba histolytica serine/threonine kinase, putative 0.026 0.0023 0.0175
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.2543 0.2484 0.4034
Loa Loa (eye worm) TK protein kinase 0.1699 0.1574 0.2044
Echinococcus multilocularis protein tyrosine kinase 0.3949 0.4001 0.4001
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0571 0.0358 0.0462
Brugia malayi Protein kinase domain containing protein 0.026 0.0023 0.0026
Schistosoma mansoni protein kinase 0.026 0.0023 0.0049
Schistosoma mansoni serine/threonine protein kinase 0.0775 0.0578 0.1439
Trypanosoma brucei SNF1-related protein kinases, putative 0.0372 0.0144 0.0228
Echinococcus granulosus tyrosine protein kinase pr2 0.026 0.0023 0.0032
Onchocerca volvulus 0.0488 0.027 0.0322
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0579 0.0367 0.3456
Echinococcus multilocularis maternal embryonic leucine zipper kinase 0.0257 0.002 0.002
Loa Loa (eye worm) TK/ACK protein kinase 0.026 0.0023 0.0026
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0911 0.0725 0.1173
Loa Loa (eye worm) hypothetical protein 0.026 0.0023 0.0026
Echinococcus granulosus tyrosine protein kinase Lyn 0.1297 0.1142 0.1851
Echinococcus multilocularis tyrosine protein kinase csk 0.026 0.0023 0.0023
Plasmodium falciparum calcium-dependent protein kinase 5 0.0579 0.0367 0.3456
Echinococcus granulosus protein kinase c epsilon type 0.0734 0.0534 0.0863
Schistosoma mansoni rap gtpase-activating protein 0.072 0.0519 0.129
Brugia malayi protein unc-22 0.0408 0.0183 0.0233
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0431 0.0208 0.0333
Trichomonas vaginalis AGC family protein kinase 0.0571 0.0358 0.3036
Trichomonas vaginalis TKL family protein kinase 0.026 0.0023 0.0168
Brugia malayi serine/threonine-protein kinase PAK 7 0.2285 0.2206 0.2866
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0579 0.0367 0.0592
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0759 0.0562 0.0726
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.0546 0.0332 0.0427
Trypanosoma brucei protein kinase, putative 0.0265 0.0029 0.0042
Schistosoma mansoni kinase 0.0405 0.018 0.0441
Schistosoma mansoni serine/threonine-protein kinase 0.0346 0.0117 0.0283
Onchocerca volvulus 0.0488 0.027 0.0322
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.032 0.0088 0.0088
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.5947 0.6154 0.8003
Schistosoma mansoni tyrosine kinase 0.026 0.0023 0.0049
Loa Loa (eye worm) hypothetical protein 0.094 0.0757 0.098
Schistosoma mansoni serine/threonine protein kinase 0.1112 0.0942 0.2348
Brugia malayi Prion-like- 0.0295 0.0062 0.0076
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0794 0.0599 0.0969
Loa Loa (eye worm) TK/FAK protein kinase 0.3993 0.4048 0.5263
Entamoeba histolytica protein kinase domain containing protein 0.026 0.0023 0.0175
Echinococcus multilocularis integrin linked protein kinase 0.026 0.0023 0.0023
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0794 0.0599 0.0969
Schistosoma mansoni serine/threonine protein kinase 0.0645 0.0439 0.1089
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.1104 0.0933 0.1511
Brugia malayi Sex muscle abnormal protein 5 0.0409 0.0184 0.0235
Schistosoma mansoni tyrosine kinase 0.026 0.0023 0.0049
Schistosoma mansoni protein kinase 0.026 0.0023 0.0049
Loa Loa (eye worm) CMGC/GSK protein kinase 0.1218 0.1057 0.1371
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0794 0.0599 0.0969
Entamoeba histolytica hypothetical protein 0.026 0.0023 0.0175
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0399 0.0173 0.1452
Loa Loa (eye worm) hypothetical protein 0.0599 0.0389 0.0501
Echinococcus granulosus roundabout 2 0.0332 0.0101 0.0158
Echinococcus granulosus tyrosine protein kinase Fyn 0.1126 0.0957 0.155
Entamoeba histolytica p21-activated kinase 0.0436 0.0214 0.188
Schistosoma mansoni hypothetical protein 0.026 0.0023 0.0049
Brugia malayi RhoGAP domain containing protein 0.0391 0.0164 0.0209
Trichomonas vaginalis TKL family protein kinase 0.026 0.0023 0.0168
Brugia malayi Tyrosine-protein kinase F09A5.2 in chromosome X, putative 0.026 0.0023 0.0026
Echinococcus granulosus roundabout 2 0.0994 0.0815 0.1319
Brugia malayi Fibronectin type III domain containing protein 0.0699 0.0496 0.0642
Schistosoma mansoni protein kinase C mu 0.112 0.0951 0.237
Toxoplasma gondii histone kinase SNF1, putative 0.0372 0.0144 0.1334
Schistosoma mansoni titin 0.0408 0.0183 0.0449
Loa Loa (eye worm) TK protein kinase 0.0574 0.0362 0.0466
Brugia malayi Protein kinase domain containing protein 0.026 0.0023 0.0026
Trichomonas vaginalis CAMK family protein kinase 0.0372 0.0144 0.1202
Echinococcus granulosus integrin linked protein kinase 0.026 0.0023 0.0032
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.1499 0.1359 0.1359
Loa Loa (eye worm) hypothetical protein 0.0295 0.0062 0.0076
Schistosoma mansoni serine/threonine protein kinase 0.0484 0.0265 0.0655
Brugia malayi Protein kinase domain containing protein 0.0337 0.0107 0.0135
Echinococcus multilocularis raf serine:threonine protein kinase 0.0421 0.0197 0.0197
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0645 0.0439 0.0566
Echinococcus granulosus protein kinase 0.0985 0.0805 0.1303
Plasmodium falciparum cGMP-dependent protein kinase 0.0277 0.0042 0.0366
Brugia malayi Protein kinase domain containing protein 0.2507 0.2446 0.3178
Brugia malayi Protein kinase c protein 2 0.0376 0.0149 0.0189
Echinococcus multilocularis TGF beta receptor type 1 0.0921 0.0736 0.0736
Entamoeba histolytica protein kinase domain containing protein 0.0282 0.0047 0.0388
Brugia malayi Fes/CIP4 homology domain containing protein 0.0858 0.0668 0.0865
Schistosoma mansoni tyrosine kinase 0.071 0.0508 0.1263
Schistosoma mansoni tyrosine kinase 0.0668 0.0464 0.1151
Schistosoma mansoni serine/threonine protein kinase 0.0784 0.0588 0.1463
Echinococcus granulosus serine:threonine protein kinase PLK1 0.032 0.0088 0.0137
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0794 0.0599 0.0599
Schistosoma mansoni serine/threonine kinase 0.0571 0.0358 0.0888
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0662 0.0457 0.1136
Plasmodium vivax tyrosine kinase-like protein, putative 0.026 0.0023 0.0186
Schistosoma mansoni tyrosine kinase 0.026 0.0023 0.0049
Brugia malayi cell division control protein 2 homolog 0.0484 0.0265 0.0341
Schistosoma mansoni serine/threonine protein kinase 0.0794 0.0599 0.1491
Trichomonas vaginalis TKL family protein kinase 0.026 0.0023 0.0168
Onchocerca volvulus 0.0488 0.027 0.0322
Echinococcus multilocularis c Jun NH2 terminal kinase 0.3062 0.3044 0.3044
Entamoeba histolytica tyrosine kinase, putative 0.026 0.0023 0.0175
Schistosoma mansoni serine/threonine protein kinase 0.0372 0.0144 0.0351
Brugia malayi Protein kinase domain containing protein 0.0488 0.027 0.0347
Loa Loa (eye worm) TK/KIN6 protein kinase 0.026 0.0023 0.0026
Onchocerca volvulus 0.0408 0.0183 0.0208
Brugia malayi Protein kinase domain containing protein 0.026 0.0023 0.0026
Loa Loa (eye worm) CMGC/CDK/CDK7 protein kinase 0.0651 0.0445 0.0575
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.026 0.0023 0.0026
Loa Loa (eye worm) AUR protein kinase 0.0639 0.0432 0.0558
Onchocerca volvulus Serine\/threonine kinase homolog 0.032 0.0088 0.0084
Brugia malayi Protein kinase domain containing protein 0.0488 0.027 0.0347
Brugia malayi Protein kinase domain containing protein 0.0457 0.0236 0.0302
Trichomonas vaginalis CMGC family protein kinase 0.0282 0.0047 0.0371
Schistosoma mansoni serine/threonine protein kinase 0.0282 0.0047 0.0109
Brugia malayi Protein kinase domain containing protein 0.026 0.0023 0.0026
Trichomonas vaginalis AGC family protein kinase 0.0745 0.0547 0.4647
Echinococcus multilocularis kinase suppressor of Ras 1 0.026 0.0023 0.0023
Trichomonas vaginalis TKL family protein kinase 0.026 0.0023 0.0168
Trichomonas vaginalis TKL family protein kinase 0.026 0.0023 0.0168
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0946 0.0763 0.0763
Loa Loa (eye worm) AGC/NDR protein kinase 0.0571 0.0358 0.0462
Trichomonas vaginalis TKL family protein kinase 0.026 0.0023 0.0168
Echinococcus multilocularis dual specificity protein kinase clk2 0.1112 0.0942 0.0942
Onchocerca volvulus 0.0473 0.0253 0.03
Schistosoma mansoni tyrosine kinase 0.026 0.0023 0.0049
Trichomonas vaginalis TKL family protein kinase 0.026 0.0023 0.0168
Giardia lamblia Kinase, PLK 0.032 0.0088 0.0721
Loa Loa (eye worm) CAMK protein kinase 0.0408 0.0183 0.0233
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0487 0.0268 0.0344
Loa Loa (eye worm) hypothetical protein 0.1533 0.1395 0.1811
Trichomonas vaginalis CAMK family protein kinase 0.0372 0.0144 0.1202
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.2933 0.2905 0.3776
Loa Loa (eye worm) SRC-1 0.1126 0.0957 0.124
Loa Loa (eye worm) TK protein kinase 0.026 0.0023 0.0026
Trypanosoma brucei AGC/RSK family serine/threonine kinase, putative 0.026 0.0023 0.0032
Trichomonas vaginalis AGC family protein kinase 0.0639 0.0432 0.3667
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.026 0.0023 0.0175
Plasmodium falciparum calcium-dependent protein kinase 2 0.0579 0.0367 0.3456
Schistosoma mansoni serine/threonine protein kinase 0.1112 0.0942 0.2348
Brugia malayi Doublecortin family protein 0.0294 0.006 0.0074
Entamoeba histolytica protein kinase, putative 0.0367 0.0139 0.1215
Loa Loa (eye worm) TK/INSR protein kinase 0.1436 0.1291 0.1676
Trichomonas vaginalis CK1 family protein kinase 0.0645 0.0439 0.3723
Loa Loa (eye worm) TK/RYK protein kinase 0.026 0.0023 0.0026
Echinococcus granulosus casein kinase I gamma 0.0359 0.013 0.0205
Echinococcus granulosus natriuretic peptide receptor 1 0.026 0.0023 0.0032
Brugia malayi Tyrosine-protein kinase PR2 0.026 0.0023 0.0026
Trypanosoma cruzi aurora B kinase, putative 0.0639 0.0432 0.0697
Echinococcus multilocularis tyrosine protein kinase csk 0.026 0.0023 0.0023
Loa Loa (eye worm) AGC/PKA protein kinase 0.0794 0.0599 0.0775
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.03 0.0066 0.0103
Echinococcus granulosus homeodomain interacting protein kinase 3 0.0348 0.0118 0.0186
Echinococcus multilocularis tyrosine protein kinase Fes:Fps 0.026 0.0023 0.0023
Echinococcus multilocularis leucine rich repeat serine:threonine protein 0.0478 0.0259 0.0259
Echinococcus multilocularis tyrosine protein kinase Abl 0.1411 0.1265 0.1265
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0282 0.0047 0.0071
Loa Loa (eye worm) protein kinase domain-containing protein 0.0359 0.013 0.0164
Loa Loa (eye worm) hypothetical protein 0.4607 0.471 0.6124
Leishmania major protein kinase, putative 0.0431 0.0208 0.0333
Schistosoma mansoni tyrosine kinase 0.0555 0.0341 0.0846
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.026 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0794 0.0599 0.0775
Brugia malayi Protein kinase domain containing protein 0.026 0.0023 0.0026
Trichomonas vaginalis CAMK family protein kinase 0.0341 0.011 0.0916
Echinococcus granulosus kinase suppressor of Ras 1 0.026 0.0023 0.0032
Echinococcus granulosus contactin 0.0332 0.0101 0.0158
Echinococcus granulosus dual specificity 0.1278 0.1121 0.1817
Schistosoma mansoni tyrosine kinase 0.0481 0.0261 0.0646
Brugia malayi protein C17H12.11 0.0639 0.0432 0.0557
Loa Loa (eye worm) CMGC/GSK protein kinase 0.1218 0.1057 0.1371
Entamoeba histolytica protein kinase domain containing protein 0.026 0.0023 0.0175
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0662 0.0457 0.1136
Loa Loa (eye worm) TK/ROR protein kinase 0.0459 0.0238 0.0306
Brugia malayi ribosomal protein S6 kinase alpha 3 0.1047 0.0872 0.113
Trichomonas vaginalis CAMK family protein kinase 0.0579 0.0367 0.3114
Trichomonas vaginalis AGC family protein kinase 0.0639 0.0432 0.3667
Loa Loa (eye worm) IKK protein kinase 0.737 0.7689 1
Onchocerca volvulus 0.0861 0.0671 0.0846
Brugia malayi Protein kinase domain containing protein 0.0488 0.027 0.0347
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.0277 0.0041 0.0062
Toxoplasma gondii protein kinase 0.026 0.0023 0.0186
Echinococcus multilocularis 0.094 0.0757 0.0757
Brugia malayi proto-oncogene tyrosine-protein kinase FER 0.026 0.0023 0.0026
Plasmodium falciparum tyrosine kinase-like protein 0.026 0.0023 0.0186
Trichomonas vaginalis STE family protein kinase 0.039 0.0163 0.1369
Echinococcus granulosus peroxidasin 0.0299 0.0065 0.01
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0794 0.0599 0.0599
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0571 0.0358 0.0577
Entamoeba histolytica tyrosine kinase, putative 0.026 0.0023 0.0175
Schistosoma mansoni protein kinase 0.0985 0.0805 0.2005
Entamoeba histolytica protein kinase, putative 0.0414 0.0189 0.1664
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0431 0.0208 0.0333
Brugia malayi hypothetical protein 0.0639 0.0432 0.0557
Entamoeba histolytica tyrosine kinase, putative 0.026 0.0023 0.0175
Schistosoma mansoni serine/threonine protein kinase 0.0346 0.0116 0.0281
Schistosoma mansoni tyrosine kinase 0.026 0.0023 0.0049
Loa Loa (eye worm) hypothetical protein 0.0299 0.0065 0.008
Echinococcus granulosus fibroblast growth factor receptor 4 0.1499 0.1359 0.2204
Echinococcus granulosus tyrosine kinase 0.026 0.0023 0.0032
Schistosoma mansoni tyrosine kinase 0.0651 0.0445 0.1105
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.1112 0.0942 0.1526
Schistosoma mansoni tyrosine kinase 0.1499 0.1359 0.3392
Echinococcus granulosus tyrosine protein kinase Srms 0.0911 0.0725 0.1173
Echinococcus multilocularis tyrosine protein kinase otk 0.0295 0.0062 0.0062
Schistosoma mansoni protein kinase 0.039 0.0163 0.04
Entamoeba histolytica tyrosine kinase, putative 0.026 0.0023 0.0175
Echinococcus granulosus serine:threonine protein kinase N2 0.1217 0.1055 0.171
Echinococcus multilocularis activin receptor type 0.4255 0.4331 0.4331
Brugia malayi Protein kinase domain containing protein 0.0308 0.0075 0.0093
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0892 0.0704 0.0704
Trypanosoma cruzi Protein kinase B 0.0346 0.0117 0.0184
Schistosoma mansoni serine/threonine protein kinase 0.0794 0.0599 0.1491
Entamoeba histolytica protein kinase, putative 0.1278 0.1121 1
Echinococcus granulosus serine:threonine protein kinase 3 0.0404 0.0178 0.0285
Trichomonas vaginalis STE family protein kinase 0.026 0.0023 0.0168
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.5947 0.6154 1
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.072 0.0519 0.129
Loa Loa (eye worm) TK/FER protein kinase 0.0488 0.027 0.0347
Echinococcus granulosus cyclin dependent kinase 1 0.0484 0.0265 0.0426
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0794 0.0599 0.0969
Trichomonas vaginalis CAMK family protein kinase 0.0372 0.0144 0.1202
Echinococcus multilocularis retinal guanylyl cyclase 2 0.026 0.0023 0.0023
Echinococcus granulosus dual specificity 0.0282 0.0047 0.0071
Loa Loa (eye worm) TK/FER protein kinase 0.0488 0.027 0.0347
Brugia malayi Egg laying defective protein 4 0.0277 0.0042 0.005
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0958 0.0776 0.1006
Trichomonas vaginalis AGC family protein kinase 0.0745 0.0547 0.4647
Schistosoma mansoni tyrosine kinase 0.1054 0.088 0.2193
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0295 0.0062 0.0146
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0332 0.0101 0.0243
Entamoeba histolytica protein kinase domain containing protein 0.026 0.0023 0.0175
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0431 0.0208 0.0208
Brugia malayi casein kinase 1, delta 0.0645 0.0439 0.0566
Brugia malayi protein kinase C II. 0.0734 0.0534 0.0691
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.2507 0.2446 0.3178
Onchocerca volvulus 0.072 0.0519 0.0647
Brugia malayi bone morphogenetic protein type 1 receptor 0.1008 0.083 0.1076
Schistosoma mansoni growth factor receptor-bound protein 0.0409 0.0184 0.0451
Schistosoma mansoni serine/threonine protein kinase 0.0319 0.0088 0.021
Entamoeba histolytica tyrosin kinase, putative 0.026 0.0023 0.0175
Schistosoma mansoni cell adhesion molecule 0.0794 0.06 0.1492
Brugia malayi Protein kinase domain containing protein 0.081 0.0617 0.0798
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.032 0.0088 0.011
Schistosoma mansoni serine/threonine protein kinase 0.0405 0.018 0.0441
Schistosoma mansoni serine/threonine protein kinase 0.051 0.0293 0.0725
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0579 0.0367 0.0592
Brugia malayi Protein kinase domain 0.039 0.0163 0.0208
Brugia malayi Tyrosine-protein kinase abl-1 0.12 0.1037 0.1345
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0409 0.0184 0.0235
Echinococcus granulosus tyrosine protein kinase Fyn 0.1126 0.0957 0.155
Schistosoma mansoni serine/threonine protein kinase 0.0794 0.0599 0.1491
Trichomonas vaginalis CMGC family protein kinase 0.1218 0.1057 0.9011
Onchocerca volvulus 0.0488 0.027 0.0322
Entamoeba histolytica protein kinase, putative 0.026 0.0023 0.0175
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.1278 0.1121 0.1817
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.2334 0.2259 0.2259
Echinococcus multilocularis protein kinase c epsilon type 0.0734 0.0534 0.0534
Entamoeba histolytica protein kinase, putative 0.026 0.0023 0.0175
Entamoeba histolytica protein kinase domain containing protein 0.026 0.0023 0.0175
Loa Loa (eye worm) TK/FER protein kinase 0.0488 0.027 0.0347
Loa Loa (eye worm) hypothetical protein 0.0858 0.0669 0.0866
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.1446 0.1302 0.1689
Echinococcus granulosus MAM 0.0353 0.0124 0.0196
Schistosoma mansoni serine/threonine protein kinase 0.0484 0.0265 0.0655
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.5947 0.6154 1
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.1075 0.0902 0.117
Echinococcus granulosus dual specificity mitogen activated protein 0.1326 0.1172 0.19
Trichomonas vaginalis CAMK family protein kinase 0.0372 0.0144 0.1202

Activities

Activity type Activity value Assay description Source Reference
IC5 (binding) = 2369 nM Inhibition of [3H]hydroxytryptamine creatinine sulfate uptake at human SERT expressed in human JAR cells ChEMBL. 19722525
IC50 (binding) = 66.7 nM Inhibition of [3H]norepinephrine uptake at human NET expressed in MDCK-Net6 cells by scintillation counting ChEMBL. 19722525
Inhibition (binding) = 20 % Inhibition of [3H]WIN-35428 binding to human recombinant DAT expressed in CHO cells at 10 uM by scintillation counting ChEMBL. 19722525
Inhibition (binding) = 46 % Inhibition of [3H]hydroxytryptamine creatinine sulfate uptake at human SERT expressed in human JAR cells at 1 uM ChEMBL. 19722525

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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