Detailed information for compound 1148008

Basic information

Technical information
  • TDR Targets ID: 1148008
  • Name: 1-(1-adamantyl)-2-imidazol-1-ylethanone
  • MW: 244.332 | Formula: C15H20N2O
  • H donors: 0 H acceptors: 2 LogP: 2.45 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(C12CC3CC(C2)CC(C1)C3)Cn1cncc1
  • InChi: 1S/C15H20N2O/c18-14(9-17-2-1-16-10-17)15-6-11-3-12(7-15)5-13(4-11)8-15/h1-2,10-13H,3-9H2
  • InChiKey: BBCQJSMDKDHVKG-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 1-(1-adamantyl)-2-imidazol-1-yl-ethanone
  • 1-(1-adamantyl)-2-(1-imidazolyl)ethanone

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis zinc finger protein 0.0058 0.043 0.042
Echinococcus multilocularis musashi 0.0029 0.0109 0.0098
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0053 0.0373 0.0351
Mycobacterium tuberculosis Conserved protein 0.0037 0.0197 0.0319
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0121 0.0098
Trichomonas vaginalis rotamase, putative 0.0071 0.0569 0.0548
Trichomonas vaginalis phosphofructokinase, putative 0.0112 0.1021 0.1004
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.006 0.0456 0.087
Echinococcus granulosus methyl CpG binding domain protein 2 0.0036 0.0189 0.0178
Brugia malayi AMP-binding enzyme family protein 0.0053 0.0375 0.0485
Schistosoma mansoni zinc finger protein 0.0058 0.043 0.0431
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0021 0.0024 0.00000000036468
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0053 0.0373 0.0347
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0084 0.0711 0.0701
Echinococcus multilocularis dna polymerase eta 0.0407 0.4279 0.4272
Loa Loa (eye worm) transcription factor SMAD2 0.0129 0.1208 0.1563
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0053 0.0377 0.0366
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0097 0.0857 0.0847
Onchocerca volvulus 0.0027 0.0088 0.011
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.003 0.0116 0.0207
Trypanosoma brucei phosphoglycerate kinase 0.0133 0.1255 0.2888
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0097 0.0857 0.2205
Schistosoma mansoni hypothetical protein 0.009 0.078 0.0782
Echinococcus multilocularis DNA methyltransferase 2, putative 0.0022 0.0028 0.0017
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0097 0.0857 0.0858
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0132 0.1244 0.2545
Loa Loa (eye worm) hypothetical protein 0.0084 0.0711 0.0921
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0133 0.1255 0.2882
Onchocerca volvulus Matrilysin homolog 0.0043 0.0258 0.0321
Loa Loa (eye worm) thioredoxin reductase 0.0052 0.0363 0.0469
Loa Loa (eye worm) hypothetical protein 0.0407 0.4279 0.5536
Trypanosoma brucei mitochondrial DNA polymerase beta 0.031 0.3213 0.7493
Schistosoma mansoni jumonji/arid domain-containing protein 0.005 0.0337 0.0338
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0084 0.0711 0.0713
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0197 0.0174
Trichomonas vaginalis phosphatidylinositol-4-phosphate 5-kinase type II, putative 0.0058 0.0426 0.0404
Onchocerca volvulus 0.0085 0.0731 0.0911
Trichomonas vaginalis CAMK family protein kinase 0.0201 0.2003 0.1993
Onchocerca volvulus Alhambra homolog 0.0033 0.0155 0.0194
Schistosoma mansoni phd finger protein 0.0026 0.0075 0.0075
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0201 0.2003 0.1994
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0112 0.1021 0.0977
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0197 0.0174
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0033 0.0155 0.0156
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0024 0.0053 0.0067
Brugia malayi Intermediate filament tail domain containing protein 0.0029 0.0109 0.0141
Onchocerca volvulus 0.0053 0.0375 0.0467
Schistosoma mansoni polybromo-1 0.0022 0.0026 0.0026
Loa Loa (eye worm) hypothetical protein 0.0026 0.0071 0.0092
Schistosoma mansoni blooms syndrome DNA helicase 0.0092 0.0805 0.0807
Entamoeba histolytica 26S proteasome non-ATPase regulatory subunit 14, putative 0.0023 0.0045 0.0017
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0072 0.0588 0.076
Echinococcus multilocularis transcription factor Dp 1 0.0044 0.0269 0.0259
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.045 0.4755 1
Loa Loa (eye worm) hypothetical protein 0.0057 0.0418 0.054
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0269 0.2762 0.3574
Trypanosoma brucei DNA polymerase kappa, putative 0.0196 0.1955 0.4532
Trichomonas vaginalis flap endonuclease-1, putative 0.003 0.0116 0.0093
Trypanosoma brucei phosphatidylinositol-4-phosphate 5-kinase, putative 0.0058 0.0426 0.0935
Schistosoma mansoni intermediate filament proteins 0.0029 0.0109 0.0109
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0362 0.3785 0.3787
Echinococcus multilocularis Phosphatidylinositol 4 phosphate 5 kinase type 1 0.0058 0.0426 0.0415
Loa Loa (eye worm) histone methyltransferase 0.0034 0.0161 0.0208
Mycobacterium tuberculosis Probable phosphoglycerate kinase Pgk 0.0362 0.3785 0.7941
Giardia lamblia Kinase, PLK 0.0201 0.2003 0.1948
Mycobacterium tuberculosis Conserved protein 0.0037 0.0197 0.0319
Trypanosoma brucei ISWI complex protein 0.0033 0.0148 0.0281
Plasmodium falciparum flap endonuclease 1 0.003 0.0116 0.0234
Mycobacterium tuberculosis Transcriptional regulatory protein 0.0053 0.0373 0.0693
Loa Loa (eye worm) hypothetical protein 0.004 0.0227 0.0293
Brugia malayi Bromodomain containing protein 0.0093 0.0811 0.1049
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0021 0.0024 0.00000000036468
Echinococcus granulosus SAM and MBT domain containing protein 0.0054 0.0389 0.0379
Leishmania major phosphatidylinositol-4-phosphate 5-kinase-like, putative 0.0058 0.0426 0.0935
Entamoeba histolytica recQ family helicase, putative 0.0039 0.0219 0.0192
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0269 0.2762 0.276
Brugia malayi PHD-finger family protein 0.0033 0.0155 0.0201
Brugia malayi hypothetical protein 0.0102 0.0914 0.1182
Schistosoma mansoni blooms syndrome DNA helicase 0.0041 0.0236 0.0236
Echinococcus multilocularis beta LACTamase domain containing family member 0.0037 0.0197 0.0186
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0084 0.0711 0.0692
Mycobacterium tuberculosis Conserved protein 0.0037 0.0197 0.0319
Leishmania major phosphatidylinositol-4-phosphate-5-kinase-likep ro tein 0.0058 0.0426 0.0935
Toxoplasma gondii thioredoxin reductase 0.0052 0.0363 0.089
Trypanosoma brucei DNA damage repair protein, putative 0.0084 0.0711 0.1607
Trypanosoma brucei DNA polymerase IV, putative 0.0382 0.4006 0.9358
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.003 0.0121 0.0069
Loa Loa (eye worm) jmjC domain-containing protein 0.005 0.0337 0.0436
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0269 0.2762 0.2754
Mycobacterium ulcerans phosphoglycerate kinase 0.0362 0.3785 0.7941
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0921 0.9955 1
Schistosoma mansoni eyes absent homolog 0.0102 0.0914 0.0915
Schistosoma mansoni cpg binding protein 0.0141 0.1341 0.1343
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0147 0.1409 0.3249
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0133 0.1255 0.2882
Trypanosoma brucei hypothetical protein, conserved 0.0084 0.0711 0.1607
Echinococcus granulosus ATP dependent DNA helicase Q1 0.008 0.0667 0.0658
Loa Loa (eye worm) 6-phosphofructokinase 0.0112 0.1021 0.1321
Toxoplasma gondii aldehyde dehydrogenase 0.006 0.0456 0.1138
Echinococcus granulosus lamin dm0 0.0029 0.0109 0.0098
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0084 0.0711 0.0692
Echinococcus multilocularis Protein lozenge 0.0055 0.0399 0.0388
Trypanosoma brucei DNA polymerase kappa, putative 0.0382 0.4006 0.9358
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0071 0.0569 0.1266
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0121 0.0248
Trypanosoma brucei hypothetical protein, conserved 0.0037 0.0197 0.0396
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0362 0.3785 0.3787
Schistosoma mansoni myelin transcription factor 1 myt1 0.0062 0.0472 0.0473
Brugia malayi phosphofructokinase 0.0112 0.1021 0.1321
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0075 0.062 0.0802
Echinococcus multilocularis matrix metallopeptidase 7 (M10 family) 0.007 0.0558 0.0548
Trichomonas vaginalis conserved hypothetical protein 0.0084 0.0711 0.0692
Echinococcus granulosus jumonji domain containing protein 0.0046 0.0299 0.0289
Leishmania major NAD dependent deacetylase, putative,transcriptional regulator, Sir2 family protein, nicotinic acid mononucleotide 5,6-dimethylbe 0.0053 0.0373 0.081
Treponema pallidum fructose-bisphosphate aldolase 0.0921 0.9955 1
Entamoeba histolytica phosphofructokinase, putative 0.0112 0.1021 0.1
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0084 0.0711 0.0701
Trypanosoma brucei DNA polymerase kappa, putative 0.0382 0.4006 0.9358
Schistosoma mansoni hypothetical protein 0.0331 0.344 0.3447
Echinococcus multilocularis alkaline phosphatase 0.0353 0.368 0.3673
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.009 0.078 0.0772
Trypanosoma brucei unspecified product 0.0354 0.3697 0.8632
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0362 0.3785 0.8838
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0038 0.0203 0.0332
Trypanosoma brucei phosphatidylinositol-4-phosphate 5-kinase, putative 0.0058 0.0426 0.0935
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0084 0.0711 0.0703
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0038 0.0203 0.0332
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0456 0.087
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0921 0.9955 1
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0072 0.0588 0.076
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0041 0.0236 0.0482
Schistosoma mansoni terminal deoxycytidyl transferase 0.0269 0.2762 0.2768
Loa Loa (eye worm) pip kinase 1 0.0058 0.0426 0.0551
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0084 0.0711 0.1601
Entamoeba histolytica hypothetical protein 0.0024 0.0053 0.0025
Loa Loa (eye worm) hypothetical protein 0.0023 0.0046 0.006
Trypanosoma brucei DNA polymerase kappa, putative 0.0297 0.3071 0.7158
Giardia lamblia Transcriptional regulator, Sir2 family 0.0053 0.0373 0.0297
Loa Loa (eye worm) 6-phosphofructokinase 0.0112 0.1021 0.1321
Toxoplasma gondii proteasome regulatory subunit 0.0023 0.0045 0.0045
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0205 0.2047 0.2052
Loa Loa (eye worm) MH2 domain-containing protein 0.0129 0.1208 0.1563
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0921 0.9955 1
Brugia malayi Hypothetical 35.8 kDa protein F37A4.5 in chromosome III 0.0023 0.0045 0.0058
Loa Loa (eye worm) hypothetical protein 0.0029 0.0103 0.0133
Plasmodium falciparum phosphoglycerate kinase 0.0362 0.3785 1
Brugia malayi F/Y-rich N-terminus family protein 0.0048 0.0322 0.0416
Brugia malayi MH2 domain containing protein 0.0129 0.1208 0.1563
Echinococcus multilocularis jumonji domain containing protein 0.0046 0.0299 0.0289
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.009 0.078 0.077
Schistosoma mansoni bromodomain containing protein 0.0151 0.1457 0.146
Echinococcus multilocularis L aminoadipate semialdehyde 0.0085 0.0731 0.0721
Onchocerca volvulus 0.0037 0.0197 0.0245
Trichomonas vaginalis conserved hypothetical protein 0.0072 0.0588 0.0567
Plasmodium vivax DNA repair protein REV1, putative 0.0084 0.0711 0.1818
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0121 0.0248
Entamoeba histolytica serine/threonine protein kinase, putative 0.0201 0.2003 0.1989
Brugia malayi Phosphoglycerate kinase 0.0133 0.1255 0.1625
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.008 0.0667 0.1699
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0037 0.0197 0.0254
Trypanosoma brucei DNA polymerase kappa, putative 0.0382 0.4006 0.9358
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0084 0.0711 0.0688
Schistosoma mansoni zinc finger protein 0.0033 0.0148 0.0148
Brugia malayi 6-phosphofructokinase 0.0112 0.1021 0.1321
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.045 0.4755 1
Loa Loa (eye worm) hypothetical protein 0.0196 0.1955 0.2529
Plasmodium vivax NLI interacting factor-like phosphatase, putative 0.0026 0.0079 0.0136
Onchocerca volvulus 0.0037 0.0197 0.0245
Loa Loa (eye worm) hypothetical protein 0.004 0.0227 0.0293
Onchocerca volvulus 0.0746 0.8021 1
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0052 0.0363 0.0672
Plasmodium vivax thioredoxin reductase, putative 0.0052 0.0363 0.089
Schistosoma mansoni alkaline phosphatase 0.0353 0.368 0.3688
Schistosoma mansoni DNA (cytosine-5)-methyltransferase 0.0022 0.0028 0.0028
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0133 0.1255 0.2888
Trichomonas vaginalis dullard protein, putative 0.0026 0.0079 0.0055
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0921 0.9955 1
Plasmodium vivax NLI interacting factor-like phosphatase, putative 0.0026 0.0079 0.0136
Brugia malayi 26S proteasome regulatory subunit rpn11 0.0023 0.0045 0.0058
Giardia lamblia Sgs1 DNA helicase, putative 0.008 0.0667 0.0595
Schistosoma mansoni lozenge 0.0055 0.0399 0.04
Brugia malayi polk-prov protein 0.0196 0.1955 0.2529
Trichomonas vaginalis penicillin-binding protein, putative 0.0037 0.0197 0.0174
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0133 0.1257 0.126
Loa Loa (eye worm) bromodomain containing protein 0.0049 0.0326 0.0422
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.006 0.0456 0.0445
Brugia malayi Disco-interacting protein 2 homolog 0.0042 0.0256 0.0331
Plasmodium vivax phosphatidylinositol-4-phosphate 5-kinase, putative 0.0058 0.0426 0.1058
Mycobacterium ulcerans hypothetical protein 0.0163 0.1592 0.3284
Echinococcus multilocularis intestinal type alkaline phosphatase 0.0353 0.368 0.3673
Onchocerca volvulus 0.0037 0.0197 0.0245
Schistosoma mansoni DNA polymerase eta 0.0407 0.4279 0.4288
Entamoeba histolytica Flap nuclease, putative 0.003 0.0116 0.0089
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0028 0.0097 0.0086
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0076 0.0632 0.0622
Echinococcus multilocularis phosphoglycerate kinase 1 0.0362 0.3785 0.3778
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0139 0.1319 0.3436
Mycobacterium ulcerans fatty-acid-CoA ligase 0.004 0.0227 0.0383
Trichomonas vaginalis phosphofructokinase, putative 0.0112 0.1021 0.1004
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0071 0.0569 0.1266
Plasmodium vivax acyl-CoA synthetase, putative 0.004 0.0227 0.0528
Schistosoma mansoni DNA helicase recq5 0.008 0.0667 0.0668
Loa Loa (eye worm) matrixin family protein 0.0046 0.03 0.0388
Echinococcus granulosus fetal alzheimer antigen falz 0.0053 0.0377 0.0367
Plasmodium vivax hypothetical protein, conserved 0.0058 0.0426 0.1058
Plasmodium vivax 26S proteasome regulatory subunit RPN11, putative 0.0023 0.0045 0.0045
Brugia malayi Pre-SET motif family protein 0.0656 0.7026 0.9092
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0024 0.0053 0.0067
Trypanosoma brucei DNA polymerase kappa, putative 0.0382 0.4006 0.9358
Echinococcus granulosus bloom syndrome protein 0.0133 0.1253 0.1246
Trypanosoma brucei hypothetical protein, conserved 0.0024 0.0053 0.006
Echinococcus granulosus intestinal type alkaline phosphatase 0.0353 0.368 0.3681
Trypanosoma cruzi DNA polymerase eta, putative 0.0221 0.2228 0.5171
Loa Loa (eye worm) pip kinase 2 0.0719 0.7728 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0921 0.9955 1
Schistosoma mansoni cpg binding protein 0.0131 0.1236 0.1239
Schistosoma mansoni apoptosis regulator bax 0.009 0.078 0.0782
Schistosoma mansoni phosphoglycerate kinase 0.0362 0.3785 0.3793
Mycobacterium leprae Probable lipase LipE 0.0037 0.0197 0.0319
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0053 0.0375 0.0698
Trypanosoma brucei DNA polymerase kappa, putative 0.0382 0.4006 0.9358
Loa Loa (eye worm) hypothetical protein 0.0021 0.0021 0.0027
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0075 0.062 0.0596
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0112 0.1021 0.207
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0084 0.0711 0.1608
Echinococcus multilocularis intestinal type alkaline phosphatase 1 0.0353 0.368 0.3673
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0297 0.3071 0.6424
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0034 0.0161 0.015
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0041 0.0236 0.0553
Trypanosoma brucei DNA polymerase eta, putative 0.0407 0.4279 1
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0053 0.0375 0.0698
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.008 0.0667 0.0862
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0297 0.3071 0.7158
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0201 0.2003 0.2592
Echinococcus granulosus expressed protein 0.0072 0.0588 0.0579
Loa Loa (eye worm) hypothetical protein 0.0102 0.0914 0.1182
Trypanosoma brucei phosphatidylinositol phosphate kinase alpha 0.0058 0.0426 0.0935
Loa Loa (eye worm) hypothetical protein 0.0037 0.0197 0.0254
Trypanosoma brucei DNA damage repair protein, putative 0.0084 0.0711 0.1607
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.031 0.3213 0.7491
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0084 0.0711 0.1601
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0132 0.1244 0.2545
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0121 0.0098
Trypanosoma brucei DNA polymerase IV, putative 0.0354 0.3697 0.8632
Trichomonas vaginalis set domain proteins, putative 0.0746 0.8021 0.8053
Trichomonas vaginalis esterase, putative 0.0037 0.0197 0.0174
Trypanosoma cruzi phosphatidylinositol (3,5) kinase, putative 0.0058 0.0426 0.0928
Leishmania major DNA polymerase kappa, putative 0.0084 0.0711 0.1607
Leishmania major hypothetical protein, conserved 0.0033 0.0148 0.0281
Mycobacterium tuberculosis Probable oxidoreductase 0.0132 0.1244 0.2545
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.0197 0.0197
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.003 0.0121 0.0182
Onchocerca volvulus 0.0029 0.0109 0.0136
Schistosoma mansoni serine/threonine protein kinase 0.0201 0.2003 0.2007
Trypanosoma brucei DNA polymerase kappa, putative 0.0214 0.2148 0.4987
Echinococcus multilocularis 26S proteasome regulatory subunit N11 0.0023 0.0045 0.0034
Leishmania major flap endonuclease-1 (FEN-1), putative 0.003 0.0116 0.0207
Schistosoma mansoni methyl-cpg binding protein mbd 0.0036 0.0189 0.0189
Mycobacterium tuberculosis Probable lipase LipE 0.0037 0.0197 0.0319
Brugia malayi SET domain containing protein 0.0021 0.002 0.0025
Plasmodium vivax hypothetical protein, conserved 0.0037 0.0197 0.0448
Plasmodium falciparum glutathione reductase 0.0052 0.0363 0.089
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.008 0.0667 0.0862
Schistosoma mansoni chromatin regulatory protein sir2 0.0053 0.0373 0.0373
Mycobacterium ulcerans hypothetical protein 0.0053 0.0375 0.0698
Echinococcus granulosus intestinal type alkaline phosphatase 1 0.0353 0.368 0.3681
Loa Loa (eye worm) acetyltransferase 0.0459 0.486 0.6289
Trichomonas vaginalis CAMK family protein kinase 0.0201 0.2003 0.1993
Trypanosoma cruzi DNA polymerase kappa, putative 0.0382 0.4006 0.9357
Leishmania major phosphatidylinositol (3,5) kinase, putative 0.0058 0.0426 0.0935
Plasmodium falciparum DNA repair protein REV1, putative 0.0084 0.0711 0.1818
Schistosoma mansoni matrix metallopeptidase-9 (M10 family) 0.0046 0.0291 0.0292
Schistosoma mansoni lamin 0.0029 0.0109 0.0109
Echinococcus granulosus alkaline phosphatase intestinal gene 2 0.0353 0.368 0.3681
Schistosoma mansoni jumonji/arid domain-containing protein 0.005 0.0337 0.0338
Toxoplasma gondii hypothetical protein 0.005 0.0341 0.0832
Schistosoma mansoni phosphoglycerate kinase 0.0362 0.3785 0.3793
Echinococcus multilocularis alkaline phosphatase, intestinal, gene 2 0.0353 0.368 0.3673
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0119 0.1098 0.2235
Brugia malayi Pip kinase protein 1 0.0058 0.0426 0.0551
Schistosoma mansoni 6-phosphofructokinase 0.0112 0.1021 0.1023
Echinococcus granulosus dna polymerase eta 0.0407 0.4279 0.4281
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0021 0.0024 0.00000000036468
Leishmania major phosphoglycerate kinase B, cytosolic 0.0362 0.3785 0.8839
Trypanosoma brucei DNA polymerase IV, putative 0.0382 0.4006 0.9358
Echinococcus granulosus histone lysine methyltransferase setb 0.0133 0.1257 0.125
Trypanosoma cruzi DNA damage repair protein, putative 0.0084 0.0711 0.1601
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0021 0.0024 0.00000000036468
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0075 0.062 0.0621
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.009 0.078 0.101
Schistosoma mansoni DNA helicase recq1 0.008 0.0667 0.0668
Echinococcus granulosus Carboxy terminal domain RNA polymerase II 0.0026 0.0079 0.0068
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0071 0.0569 0.1272
Loa Loa (eye worm) hypothetical protein 0.0037 0.0197 0.0254
Brugia malayi Thioredoxin reductase 0.0052 0.0363 0.0469
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.003 0.0116 0.02
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0062 0.0472 0.0463
Trypanosoma brucei phosphoglycerate kinase, putative 0.0133 0.1255 0.2888
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.0022 0.0031 0.0007
Giardia lamblia DINP protein human, muc B family 0.0297 0.3071 0.3029
Toxoplasma gondii PPIC-type PPIASE domain-containing protein 0.0022 0.0031 0.0008
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0024 0.0053 0.0067
Loa Loa (eye worm) hypothetical protein 0.0441 0.4657 0.6026
Echinococcus granulosus L aminoadipate semialdehyde 0.0085 0.0731 0.0722
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0053 0.0375 0.0698
Brugia malayi PHD-finger family protein 0.007 0.0556 0.0719
Trypanosoma cruzi phosphatidylinositol-4-phosphate 5-kinase, putative 0.0058 0.0426 0.0928
Schistosoma mansoni phosphatidylinositol-4-phosphate-5-kinaseputativ e 0.0058 0.0426 0.0426
Trypanosoma brucei polo-like protein kinase 0.0201 0.2003 0.4646
Echinococcus granulosus disco interacting protein 2 0.0045 0.028 0.027
Trypanosoma brucei DNA polymerase kappa, putative 0.0382 0.4006 0.9358
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0121 0.0248
Brugia malayi beta-lactamase 0.0037 0.0197 0.0254
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0214 0.2155 0.2147
Toxoplasma gondii PHD-finger domain-containing protein 0.0033 0.0155 0.0339
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.003 0.0121 0.0043
Loa Loa (eye worm) hypothetical protein 0.0053 0.0375 0.0485
Echinococcus granulosus beta LACTamase domain containing family member 0.0037 0.0197 0.0186
Schistosoma mansoni SET domain protein 0.0039 0.0221 0.0221
Echinococcus granulosus thioredoxin glutathione reductase 0.0052 0.0363 0.0353
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0197 0.0174
Echinococcus multilocularis flap endonuclease 1 0.003 0.0116 0.0105
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0024 0.0053 0.0015
Trichomonas vaginalis CAMK family protein kinase 0.0099 0.0885 0.0866
Loa Loa (eye worm) hypothetical protein 0.004 0.0227 0.0293
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0921 0.9955 1
Echinococcus granulosus cpg binding protein 0.0141 0.1341 0.1334
Schistosoma mansoni phosphatidylinositol-4-phosphate 5-kinase type II 0.0719 0.7728 0.7744
Echinococcus multilocularis lamin dm0 0.0029 0.0109 0.0098
Brugia malayi Bromodomain containing protein 0.0176 0.1732 0.2241
Trypanosoma cruzi trypanothione reductase, putative 0.0052 0.0363 0.078
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0201 0.2003 0.4646
Trypanosoma cruzi DNA polymerase kappa, putative 0.0382 0.4006 0.9357
Trichomonas vaginalis CAMK family protein kinase 0.0201 0.2003 0.1993
Entamoeba histolytica acyl-CoA synthetase, putative 0.0053 0.0375 0.0349
Entamoeba histolytica recQ family DNA helicase 0.0041 0.0236 0.0209
Leishmania major DNA polymerase eta, putative 0.0221 0.2228 0.5175
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0214 0.2155 0.2151
Brugia malayi beta-lactamase family protein 0.0037 0.0197 0.0254
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0024 0.0053 0.0015
Plasmodium vivax NAD-dependent deacetylase, putative 0.0053 0.0373 0.0917
Echinococcus granulosus phosphatidylinositol 5 phosphate 4 kinase type 2 0.0719 0.7728 0.7742
Leishmania major DNA damage repair protein, putative 0.0084 0.0711 0.1607
Schistosoma mansoni hypothetical protein 0.009 0.078 0.0782
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0037 0.0197 0.0319
Trichomonas vaginalis nuclear lim interactor-interacting factor, putative 0.0026 0.0079 0.0055
Plasmodium falciparum phd finger protein, putative 0.0033 0.0155 0.0339
Trypanosoma brucei Silent information regulator 2 related protein 3 0.0053 0.0373 0.081
Schistosoma mansoni bromodomain containing protein 0.0026 0.0071 0.0071
Echinococcus multilocularis expressed protein 0.0072 0.0588 0.0577
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0021 0.0024 0.00000000036468
Brugia malayi Bromodomain containing protein 0.0049 0.0334 0.0432
Echinococcus granulosus intermediate filament protein 0.0029 0.0109 0.0098
Mycobacterium ulcerans NAD-dependent deacetylase 0.0053 0.0373 0.0693
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.009 0.0783 0.0775
Trichomonas vaginalis phosphatidylinositol-4-phosphate 5-kinase type II, putative 0.0058 0.0426 0.0404
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0147 0.1409 0.3244
Loa Loa (eye worm) hypothetical protein 0.009 0.078 0.101
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0112 0.102 0.2639
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0084 0.0711 0.064
Brugia malayi Carboxy-terminal domain RNA polymerase II polypeptide A smallphosphatase 1 0.0026 0.0079 0.0102
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0039 0.0217 0.0218
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0269 0.2762 0.2768
Giardia lamblia Hypothetical protein 0.0058 0.0426 0.0351
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0112 0.1021 0.2336
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0121 0.0248
Echinococcus multilocularis 0.0026 0.0079 0.0068
Trypanosoma brucei DNA polymerase kappa, putative 0.0214 0.2148 0.4987
Loa Loa (eye worm) hypothetical protein 0.0026 0.0076 0.0098
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0024 0.0053 0.0015
Mycobacterium leprae Probable NAD-dependent deacetylase NpdA (Regulatory protein SIR2 homolog) 0.0036 0.0186 0.0298
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0119 0.1098 0.2235
Loa Loa (eye worm) hypothetical protein 0.0082 0.0689 0.0892
Trypanosoma brucei DNA polymerase kappa, putative 0.0382 0.4006 0.9358
Trichomonas vaginalis CAMK family protein kinase 0.0201 0.2003 0.1993
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0062 0.0472 0.0462
Trypanosoma cruzi DNA polymerase kappa, putative 0.0382 0.4006 0.9357
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0133 0.1257 0.1247
Brugia malayi Bloom's syndrome protein homolog 0.0133 0.1253 0.1621
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0075 0.062 0.0802
Loa Loa (eye worm) hypothetical protein 0.0053 0.0375 0.0485
Loa Loa (eye worm) FYVE zinc finger family protein 0.0058 0.0426 0.0551
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0139 0.1319 0.3436
Schistosoma mansoni hypothetical protein 0.0183 0.1811 0.1814
Trypanosoma cruzi Silent information regulator 2 related protein 3 0.0053 0.0373 0.0804
Trichomonas vaginalis DNA helicase recq1, putative 0.0133 0.1253 0.1237
Trichomonas vaginalis CAMK family protein kinase 0.0099 0.0885 0.0866
Loa Loa (eye worm) mbt repeat family protein 0.0054 0.0389 0.0503
Mycobacterium tuberculosis Probable lipase LipD 0.0037 0.0197 0.0319
Loa Loa (eye worm) flap endonuclease-1 0.003 0.0116 0.015
Trichomonas vaginalis nuclear lim interactor-interacting factor, putative 0.0026 0.0079 0.0055
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0053 0.0375 0.0698
Loa Loa (eye worm) hypothetical protein 0.0037 0.0197 0.0254
Echinococcus multilocularis dnaJ subfamily B 0.0923 0.9979 0.9979
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0038 0.0203 0.0332
Mycobacterium tuberculosis Probable hydrolase 0.0037 0.0197 0.0319
Leishmania major hypothetical protein, conserved 0.0037 0.0197 0.0396
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0091 0.0788 0.1787
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0119 0.1098 0.2235
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0459 0.486 0.4854
Echinococcus granulosus phosphatidylinositol phosphate 5 kinase type III 0.0058 0.0426 0.0416
Onchocerca volvulus 0.0054 0.0389 0.0485
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0075 0.062 0.0611
Mycobacterium tuberculosis Probable reductase 0.0119 0.1098 0.2235
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0122 0.1131 0.2937
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0121 0.0098
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0362 0.3785 0.8838
Echinococcus granulosus dna polymerase kappa 0.0382 0.4006 0.4007
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.031 0.3213 0.7491
Brugia malayi mbt repeat family protein 0.0054 0.0389 0.0503
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0044 0.027 0.0562
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0084 0.0711 0.0921
Loa Loa (eye worm) beta-lactamase 0.0037 0.0197 0.0254
Giardia lamblia Phosphatidylinositol-4-phosphate 5-kinase, putative 0.0058 0.0426 0.0351
Toxoplasma gondii peptidylprolyl isomerase 0.0071 0.0569 0.1439
Trichomonas vaginalis DNA helicase recq, putative 0.0133 0.1253 0.1237
Schistosoma mansoni phosphatidylinositol-4-phosphate 5-kinase type II 0.0058 0.0426 0.0426
Trichomonas vaginalis nuclear lim interactor-interacting factor, putative 0.0026 0.0079 0.0055
Schistosoma mansoni hypothetical protein 0.0914 0.9875 0.9895
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0236 0.2397 0.4992
Loa Loa (eye worm) hypothetical protein 0.015 0.1449 0.1875
Brugia malayi mbt repeat family protein 0.0054 0.0389 0.0503
Trichomonas vaginalis dullard protein, putative 0.0026 0.0079 0.0055
Echinococcus multilocularis geminin 0.0914 0.9875 0.9874
Echinococcus multilocularis 6 phosphofructokinase 0.0112 0.1021 0.1011
Loa Loa (eye worm) hypothetical protein 0.004 0.0227 0.0293
Giardia lamblia DNA damage repair protein 0.0084 0.0711 0.064
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0382 0.4006 0.4009
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.003 0.0116 0.0234
Onchocerca volvulus 0.0131 0.1236 0.1541
Toxoplasma gondii phosphoglycerate kinase PGKI 0.0362 0.3785 1
Loa Loa (eye worm) hypothetical protein 0.0062 0.0472 0.0611
Echinococcus multilocularis histone acetyltransferase MYST2 0.0062 0.0472 0.0462
Echinococcus granulosus matrix metallopeptidase 7 M10 family 0.007 0.0558 0.0549
Brugia malayi ImpB/MucB/SamB family protein 0.0407 0.4279 0.5536
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.0197 0.0197
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.003 0.0121 0.0182
Trypanosoma brucei phosphatidylinositol (3,5) kinase, putative 0.0058 0.0426 0.0935
Loa Loa (eye worm) hypothetical protein 0.0037 0.0197 0.0254
Trichomonas vaginalis nuclear lim interactor-interacting factor, putative 0.0026 0.0079 0.0055
Schistosoma mansoni aldehyde dehydrogenase 0.006 0.0456 0.0457
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0147 0.1409 0.3249
Trypanosoma cruzi polo-like protein kinase, putative 0.0201 0.2003 0.4642
Schistosoma mansoni nuclear lim interactor-interacting factor (nli-interacting factor) (nli-if) 0.0026 0.0079 0.0079
Brugia malayi acetyltransferase, GNAT family protein 0.0459 0.486 0.6289
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0038 0.0203 0.0332
Entamoeba histolytica phosphoinositide kinase, putative 0.0058 0.0426 0.04
Giardia lamblia PHD finger protein 15 0.0033 0.0155 0.0077
Trichomonas vaginalis penicillin-binding protein, putative 0.0037 0.0197 0.0174
Echinococcus granulosus ubiquitin specific protease 41 0.0084 0.0711 0.0703
Mycobacterium ulcerans DNA polymerase IV 0.0382 0.4006 0.8409
Brugia malayi jmjC domain containing protein 0.0109 0.0991 0.1282
Trypanosoma brucei unspecified product 0.0186 0.1839 0.4261
Plasmodium vivax glutathione reductase, putative 0.0052 0.0363 0.089
Trypanosoma cruzi 3-phosphoglycerate kinase, glycosomal 0.0133 0.1255 0.2882
Entamoeba histolytica phosphoglycerate kinase, putative 0.0362 0.3785 0.3785
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0109 0.0991 0.0983
Schistosoma mansoni phosphatidylinositol-4-phosphate 5-kinase type II 0.0719 0.7728 0.7744
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0021 0.0024 0.00000000036468
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.009 0.078 0.0782
Schistosoma mansoni DNA polymerase IV / kappa 0.0084 0.0711 0.0713
Toxoplasma gondii histone lysine methyltransferase SET1 0.0199 0.199 0.5221
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0133 0.1255 0.2882
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.008 0.0667 0.0656
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0133 0.1255 0.2882
Schistosoma mansoni disco-interacting protein 2 (dip2) 0.0045 0.028 0.0281
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.004 0.0227 0.0383
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0121 0.0098
Brugia malayi 6-phosphofructokinase 0.0112 0.1021 0.1321
Echinococcus granulosus mixed lineage leukemia protein mll 0.0028 0.0097 0.0087
Trypanosoma cruzi phosphatidylinositol-4-phosphate 5-kinase, putative 0.0058 0.0426 0.0928
Loa Loa (eye worm) runx1 0.0055 0.0399 0.0516
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.009 0.078 0.0772
Brugia malayi glutathione reductase 0.0052 0.0363 0.0469
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0075 0.062 0.1391
Brugia malayi serine/threonine-protein kinase plk-2 0.0201 0.2003 0.2592
Trypanosoma cruzi ISWI complex protein 0.0033 0.0148 0.0274
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0044 0.027 0.0562
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0112 0.1021 0.233
Trypanosoma brucei DNA polymerase kappa, putative 0.0382 0.4006 0.9358
Loa Loa (eye worm) 26S proteasome regulatory subunit rpn11 0.0023 0.0045 0.0058
Echinococcus granulosus transcription factor Dp 1 0.0044 0.0269 0.0259
Plasmodium vivax SET domain containing protein 0.0023 0.004 0.0031
Echinococcus granulosus Phosphatidylinositol 4 phosphate 5 kinase type 1 0.0058 0.0426 0.0416
Echinococcus granulosus histone lysine N methyltransferase NSD3 0.0039 0.0221 0.021
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0119 0.1098 0.2235
Schistosoma mansoni phosphatidylinositol-4-phosphate 5-kinase type I 0.0058 0.0426 0.0426
Giardia lamblia Histone acetyltransferase GCN5 0.0122 0.114 0.1075
Plasmodium vivax flap endonuclease 1, putative 0.003 0.0116 0.0234
Echinococcus multilocularis SAM and MBT domain containing protein 0.0054 0.0389 0.0378
Trypanosoma brucei DNA polymerase kappa, putative 0.0214 0.2148 0.4987
Mycobacterium ulcerans acyl-CoA synthetase 0.0053 0.0375 0.0698
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0459 0.486 0.487
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0656 0.7026 0.9092
Trypanosoma brucei hypothetical protein, conserved 0.0084 0.0711 0.1607
Trypanosoma cruzi ISWI complex protein 0.0033 0.0148 0.0274
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0109 0.0991 0.0981
Trypanosoma cruzi Silent information regulator 2 related protein 3 0.0053 0.0373 0.0804
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.006 0.0456 0.1006
Loa Loa (eye worm) hypothetical protein 0.0362 0.3785 0.4898
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0075 0.062 0.1385
Trypanosoma cruzi DNA damage repair protein, putative 0.0084 0.0711 0.1601
Mycobacterium ulcerans acyl-CoA synthetase 0.0053 0.0375 0.0698
Schistosoma mansoni hypothetical protein 0.0914 0.9875 0.9895
Loa Loa (eye worm) jmjC domain-containing protein 0.0069 0.0546 0.0707
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0024 0.0053 0.0067
Toxoplasma gondii histone deacetylase SIR2 0.0053 0.0373 0.0917
Entamoeba histolytica acyl-CoA synthetase, putative 0.0053 0.0375 0.0349
Trypanosoma cruzi polo-like protein kinase, putative 0.0201 0.2003 0.4642
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.008 0.0667 0.1699
Echinococcus granulosus 6 phosphofructokinase 0.0112 0.1021 0.1013
Giardia lamblia Flap structure-specific endonuclease 0.003 0.0116 0.0038
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0139 0.1319 0.3436
Trichomonas vaginalis phosphofructokinase, putative 0.0112 0.1021 0.1004
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0037 0.0197 0.0319
Schistosoma mansoni jumonji domain containing protein 0.0087 0.0744 0.0745
Toxoplasma gondii phosphoglycerate kinase PGKII 0.0362 0.3785 1
Echinococcus granulosus zinc finger protein 0.0058 0.043 0.0421
Leishmania major mitochondrial DNA polymerase beta 0.031 0.3213 0.7493
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0084 0.0711 0.0703
Trichomonas vaginalis DNA polymerase eta, putative 0.0382 0.4006 0.4009
Schistosoma mansoni hypothetical protein 0.0033 0.0148 0.0148
Leishmania major phosphoglycerate kinase C, glycosomal 0.0362 0.3785 0.8839
Trypanosoma brucei Mitochondrial import inner membrane translocase subunit TIM50 0.0026 0.0079 0.012
Trypanosoma cruzi phosphatidylinositol 4-phosphate 5-kinase alpha, putative 0.0058 0.0426 0.0928
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.009 0.078 0.077
Giardia lamblia Fructose-bisphosphate aldolase 0.0921 0.9955 1
Trypanosoma cruzi DNA polymerase eta, putative 0.0407 0.4279 1
Brugia malayi CXXC zinc finger family protein 0.0131 0.1236 0.16
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0081 0.0684 0.1745
Brugia malayi Flap endonuclease-1 0.003 0.0116 0.015
Onchocerca volvulus Serine\/threonine kinase homolog 0.0201 0.2003 0.2497
Echinococcus multilocularis dna polymerase kappa 0.0382 0.4006 0.3999
Trypanosoma brucei phosphoglycerate kinase 0.0362 0.3785 0.8839
Brugia malayi FYVE finger-containing phosphoinositide kinase, putative 0.0058 0.0426 0.0551
Loa Loa (eye worm) hypothetical protein 0.004 0.0227 0.0293
Loa Loa (eye worm) RecQ helicase 0.0133 0.1253 0.1621
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0121 0.0098
Schistosoma mansoni 6-phosphofructokinase 0.0112 0.1021 0.1023
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0084 0.0711 0.0713
Onchocerca volvulus 0.0719 0.7728 0.9635
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0085 0.0731 0.0946
Trichomonas vaginalis DNA helicase recq, putative 0.0091 0.0788 0.0769
Trypanosoma cruzi DNA polymerase kappa, putative 0.0382 0.4006 0.9357
Mycobacterium ulcerans hypothetical protein 0.0084 0.0711 0.1413
Schistosoma mansoni kinase 0.0102 0.0914 0.0916
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0144 0.1373 0.1366
Brugia malayi PHD-finger family protein 0.002 0.0012 0.0016
Echinococcus granulosus lamin 0.0029 0.0109 0.0098
Mycobacterium ulcerans DNA polymerase IV 0.0382 0.4006 0.8409
Entamoeba histolytica acetyltransferase, GNAT family 0.0122 0.114 0.1121
Toxoplasma gondii hypothetical protein 0.0093 0.0816 0.2097
Leishmania major ATP-dependent phosphofructokinase 0.0112 0.1021 0.2336
Echinococcus granulosus phosphoglycerate kinase 1 0.0362 0.3785 0.3786
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0075 0.062 0.0609
Schistosoma mansoni nuclear lim interactor-interacting factor (nli-interacting factor) (nli-if) 0.0026 0.0079 0.0079
Entamoeba histolytica phosphofructokinase, putative 0.0112 0.1021 0.1
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0456 0.087
Loa Loa (eye worm) hypothetical protein 0.0719 0.7728 1
Toxoplasma gondii ABC1 family protein 0.0037 0.0197 0.0448
Giardia lamblia Phosphoglycerate kinase 0.0362 0.3785 0.3753
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.003 0.0121 0.0094
Loa Loa (eye worm) hypothetical protein 0.0033 0.0155 0.0201
Brugia malayi Pre-SET motif family protein 0.0097 0.0857 0.1108
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0053 0.0377 0.0378
Echinococcus multilocularis lamin 0.0029 0.0109 0.0098
Echinococcus multilocularis disco interacting protein 2 0.0045 0.028 0.0269
Loa Loa (eye worm) hypothetical protein 0.0026 0.0079 0.0102
Brugia malayi Phosphoglycerate kinase 0.0362 0.3785 0.4898
Plasmodium vivax SET domain protein, putative 0.0097 0.0857 0.2205
Plasmodium falciparum phosphatidylinositol-4-phosphate 5-kinase 0.0058 0.0426 0.1058
Loa Loa (eye worm) ATP-dependent DNA helicase 0.008 0.0667 0.0862
Plasmodium falciparum 26S proteasome regulatory subunit RPN11, putative 0.0023 0.0045 0.0045
Treponema pallidum phosphoglycerate kinase 0.0362 0.3785 0.3769
Trichomonas vaginalis phosphofructokinase, putative 0.0112 0.1021 0.1004
Loa Loa (eye worm) MBCTL1 0.0062 0.0472 0.0611
Echinococcus multilocularis thioredoxin glutathione reductase 0.0052 0.0363 0.0352
Echinococcus multilocularis ubiquitin specific protease 41 0.0084 0.0711 0.0701
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.006 0.0456 0.0446
Loa Loa (eye worm) hypothetical protein 0.0041 0.0236 0.0305
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0121 0.0098
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0132 0.1244 0.2545
Echinococcus granulosus peregrin 0.0059 0.0442 0.0432
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0201 0.2003 0.1998
Plasmodium vivax ATP-dependent DNA helicase Q1, putative 0.0039 0.0219 0.0508
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0034 0.0161 0.015
Brugia malayi Pip kinase protein 2 0.0719 0.7728 1
Echinococcus granulosus polybromo 1 0.0022 0.0026 0.0015
Echinococcus granulosus PHD finger protein rhinoceros 0.0033 0.0155 0.0145
Schistosoma mansoni lamin 0.0029 0.0109 0.0109
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0044 0.027 0.0562
Toxoplasma gondii 6-phosphofructokinase 0.003 0.0121 0.0248
Echinococcus granulosus ATP dependent DNA helicase Q5 0.008 0.0667 0.0658
Schistosoma mansoni sex comb on midleg homolog 0.0054 0.0389 0.039
Loa Loa (eye worm) hypothetical protein 0.0054 0.0389 0.0503
Loa Loa (eye worm) matrixin family protein 0.0043 0.0258 0.0334
Schistosoma mansoni rotamase 0.0072 0.0588 0.0589
Trichomonas vaginalis CAMK family protein kinase 0.0201 0.2003 0.1993
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0084 0.0711 0.1608
Loa Loa (eye worm) hypothetical protein 0.002 0.0012 0.0016
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0054 0.0389 0.039
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0921 0.9955 1
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0062 0.0472 0.0611
Schistosoma mansoni methyl-cpg binding protein mbd 0.0036 0.0189 0.0189
Treponema pallidum ATP-dependent DNA helicase 0.0041 0.0236 0.0184
Echinococcus granulosus histone acetyltransferase KAT2B 0.0442 0.4664 0.4668
Toxoplasma gondii phosphatidylinositol-4-phosphate 5-kinase 0.0058 0.0426 0.1058
Mycobacterium ulcerans beta-lactamase 0.0037 0.0197 0.0319
Echinococcus multilocularis Carboxy terminal domain RNA polymerase II 0.0026 0.0079 0.0068
Plasmodium vivax phosphoglycerate kinase, putative 0.0362 0.3785 1
Wolbachia endosymbiont of Brugia malayi phosphoglycerate kinase 0.0362 0.3785 1
Trypanosoma brucei chrX additional, unordered contigs 0.0084 0.0711 0.1607
Schistosoma mansoni cpg binding protein 0.0141 0.1341 0.1343
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.004 0.0227 0.0464
Loa Loa (eye worm) PHD-finger family protein 0.0044 0.0273 0.0353
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0029 0.0109 0.0141
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0075 0.062 0.1391
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0112 0.1021 0.207
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0084 0.0711 0.1818
Trypanosoma brucei unspecified product 0.0186 0.1839 0.4261
Chlamydia trachomatis phosphoglycerate kinase 0.0362 0.3785 1
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0075 0.062 0.1385
Loa Loa (eye worm) glutathione reductase 0.0052 0.0363 0.0469
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0053 0.0375 0.0698
Loa Loa (eye worm) hypothetical protein 0.0029 0.0109 0.0141
Plasmodium vivax hypothetical protein, conserved 0.0033 0.0155 0.0339
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0041 0.0236 0.0482
Loa Loa (eye worm) hypothetical protein 0.008 0.0667 0.0862
Trypanosoma cruzi hypothetical protein, conserved 0.0026 0.0079 0.0113
Echinococcus multilocularis peregrin 0.0059 0.0442 0.0431
Mycobacterium ulcerans hypothetical protein 0.0037 0.0197 0.0319
Trypanosoma cruzi hypothetical protein, conserved 0.0084 0.0711 0.1601
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.008 0.0667 0.1699
Echinococcus multilocularis phosphatidylinositol 5 phosphate 4 kinase type 2 0.0719 0.7728 0.7726
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0083 0.0701 0.1791
Echinococcus multilocularis lysine specific demethylase 5A 0.004 0.0233 0.0222
Plasmodium falciparum acyl-CoA synthetase 0.004 0.0227 0.0528
Leishmania major trypanothione reductase 0.0052 0.0363 0.0787
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0054 0.0389 0.0485
Trichomonas vaginalis 6-phosphofructokinase, putative 0.003 0.0121 0.0098
Echinococcus granulosus CTD small phosphatase protein like 0.0026 0.0079 0.0068
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0221 0.2228 0.5854
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0037 0.0197 0.0319
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0139 0.1319 0.1304
Mycobacterium ulcerans acyl-CoA synthetase 0.0053 0.0375 0.0698
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0119 0.1098 0.2235
Leishmania major DNA polymerase eta, putative 0.0407 0.4279 1
Mycobacterium tuberculosis Probable dehydrogenase 0.0119 0.1098 0.2235
Mycobacterium ulcerans lipase LipD 0.0037 0.0197 0.0319
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0036 0.0189 0.0178
Entamoeba histolytica NLI interacting factor-like phosphatase domain-containing protein 0.0026 0.0079 0.0051
Echinococcus granulosus 26S proteasome regulatory subunit N11 0.0023 0.0045 0.0034
Entamoeba histolytica phosphatidylinositol-4-phosphate 5-kinase, putative 0.0058 0.0426 0.04
Mycobacterium leprae conserved hypothetical protein 0.0024 0.0053 0.0015
Entamoeba histolytica recQ family helicase, putative 0.0091 0.0788 0.0765
Echinococcus multilocularis polycomb protein SCMH1 0.0054 0.0389 0.0378
Brugia malayi Hemopexin family protein 0.0027 0.0088 0.0114
Trichomonas vaginalis bromodomain-containing protein, putative 0.0139 0.1319 0.1304
Plasmodium falciparum thioredoxin reductase 0.0052 0.0363 0.089
Mycobacterium tuberculosis Probable esterase LipL 0.0037 0.0197 0.0319
Trypanosoma cruzi hypothetical protein, conserved 0.0084 0.0711 0.1601
Brugia malayi intermediate filament protein 0.0029 0.0109 0.0141
Mycobacterium leprae Probable phosphoglycerate kinase Pgk 0.0362 0.3785 0.7941
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0921 0.9955 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0021 0.0024 0.00000000036468
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0037 0.0197 0.0319
Trypanosoma brucei phosphoglycerate kinase 0.0362 0.3785 0.8839
Brugia malayi beta-lactamase family protein 0.0037 0.0197 0.0254
Loa Loa (eye worm) hypothetical protein 0.0102 0.0914 0.1182
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0053 0.0375 0.0698
Brugia malayi ImpB/MucB/SamB family protein 0.0269 0.2762 0.3574
Schistosoma mansoni hypothetical protein 0.0033 0.0155 0.0156
Mycobacterium tuberculosis Conserved hypothetical protein 0.0269 0.2762 0.5769
Trypanosoma cruzi phosphatidylinositol-4-phosphate 5-kinase-like, putative 0.0058 0.0426 0.0928
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0197 0.0389
Loa Loa (eye worm) PHD-finger family protein 0.0033 0.0155 0.0201
Loa Loa (eye worm) FYVE finger-containing phosphoinositide kinase 0.0058 0.0426 0.0551
Loa Loa (eye worm) hypothetical protein 0.0107 0.0972 0.1258
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0024 0.0053 0.0059
Onchocerca volvulus 0.0441 0.4657 0.5806
Onchocerca volvulus Matrix metalloproteinase homolog 0.0043 0.0258 0.0321
Echinococcus granulosus alkaline phosphatase 0.0353 0.368 0.3681
Schistosoma mansoni hypothetical protein 0.0923 0.9979 1
Mycobacterium tuberculosis Probable DNA polymerase IV DinX (pol IV 1) (DNA nucleotidyltransferase (DNA-directed)) 0.0028 0.0097 0.0107
Trypanosoma cruzi phosphatidylinositol-4-phosphate 5-kinase-like, putative 0.0058 0.0426 0.0928
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0093 0.0816 0.2097
Toxoplasma gondii phosphofructokinase domain-containing protein 0.003 0.0121 0.0248
Trichomonas vaginalis CAMK family protein kinase 0.0201 0.2003 0.1993
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0921 0.9955 1
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0028 0.0097 0.0086
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0456 0.087
Trypanosoma cruzi phosphatidylinositol-4-phosphate 5-kinase type II beta, putative 0.0058 0.0426 0.0928
Loa Loa (eye worm) hypothetical protein 0.0053 0.0375 0.0485
Loa Loa (eye worm) hypothetical protein 0.0441 0.4657 0.6026
Schistosoma mansoni alkaline phosphatase 0.0353 0.368 0.3688
Echinococcus granulosus geminin 0.0914 0.9875 0.9895
Brugia malayi polybromodomain protein 0.0021 0.0021 0.0027
Echinococcus multilocularis phosphatidylinositol phosphate 5 kinase type III 0.0058 0.0426 0.0415
Leishmania major 4-coumarate:coa ligase-like protein 0.0053 0.0375 0.0816
Loa Loa (eye worm) hypothetical protein 0.0296 0.3061 0.3961
Trypanosoma brucei DNA polymerase kappa, putative 0.0196 0.1955 0.4532
Loa Loa (eye worm) hypothetical protein 0.0133 0.1257 0.1627
Mycobacterium tuberculosis Conserved hypothetical protein 0.0163 0.1592 0.3284
Entamoeba histolytica acyl-coA synthetase, putative 0.0053 0.0375 0.0349
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0037 0.0197 0.0254
Trypanosoma brucei DNA polymerase kappa, putative 0.0382 0.4006 0.9358
Brugia malayi AMP-binding enzyme family protein 0.0053 0.0375 0.0485
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0133 0.1257 0.126
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0076 0.0632 0.0623
Loa Loa (eye worm) hypothetical protein 0.0042 0.0256 0.0331
Echinococcus granulosus lysine specific demethylase 5A 0.005 0.0337 0.0327
Loa Loa (eye worm) hypothetical protein 0.0085 0.0731 0.0946
Echinococcus granulosus histone acetyltransferase MYST2 0.0062 0.0472 0.0463
Entamoeba histolytica phosphofructokinase, putative 0.0112 0.1021 0.1
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0144 0.1373 0.1363
Brugia malayi hypothetical protein 0.0441 0.4657 0.6026
Loa Loa (eye worm) CXXC zinc finger family protein 0.0131 0.1236 0.16
Mycobacterium ulcerans esterase/lipase LipP 0.0037 0.0197 0.0319
Schistosoma mansoni phosphatidylinositol-4-phosphate 5-kinase type II 0.0058 0.0426 0.0426
Schistosoma mansoni SET domain protein 0.0026 0.0074 0.0074
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0921 0.9955 1
Loa Loa (eye worm) phosphofructokinase 0.0112 0.1021 0.1321
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0091 0.0788 0.1787
Toxoplasma gondii phosphatidylinositol-4-phosphate 5-Kinase 0.0058 0.0426 0.1058
Echinococcus granulosus histone acetyltransferase KAT2B 0.0139 0.1319 0.1312
Brugia malayi AMP-binding enzyme family protein 0.0053 0.0375 0.0485
Entamoeba histolytica deoxycytidyl transferase, putative 0.0269 0.2762 0.2754
Loa Loa (eye worm) intermediate filament protein 0.0029 0.0109 0.0141
Toxoplasma gondii phosphatidylinositol-4-phosphate 5-Kinase 0.0058 0.0426 0.1058
Schistosoma mansoni sex comb on midleg homolog 0.0054 0.0389 0.039
Onchocerca volvulus 0.0097 0.0857 0.1068
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0097 0.0857 0.0858
Loa Loa (eye worm) apoptosis regulator protein 0.009 0.078 0.101
Echinococcus granulosus dnaJ subfamily B 0.0923 0.9979 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0021 0.0024 0.00000000036468
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0071 0.0569 0.1272
Schistosoma mansoni hypothetical protein 0.0027 0.0088 0.0089
Trichomonas vaginalis CAMK family protein kinase 0.0201 0.2003 0.1993
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0053 0.0375 0.0698
Trypanosoma brucei trypanothione reductase 0.0052 0.0363 0.0787
Plasmodium falciparum histone acetyltransferase GCN5 0.0122 0.114 0.2961
Leishmania major peptidyl-prolyl cis-trans isomerase, putative 0.0022 0.0031 0.0007
Schistosoma mansoni hypothetical protein 0.0026 0.0076 0.0076
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0044 0.027 0.0569
Onchocerca volvulus 0.0029 0.0109 0.0136
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0197 0.0389
Toxoplasma gondii PHD-finger domain-containing protein 0.0033 0.0155 0.0339
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0053 0.0373 0.0351
Echinococcus granulosus flap endonuclease 1 0.003 0.0116 0.0106
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.008 0.0667 0.0656
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0028 0.0097 0.0087
Echinococcus multilocularis histone lysine N methyltransferase NSD3 0.0039 0.0221 0.021
Echinococcus granulosus DNA methyltransferase 2, putative 0.0022 0.0028 0.0017
Leishmania major DNA polymerase kappa, putative 0.0297 0.3071 0.7158
Toxoplasma gondii Dullard family phosphatase domain-containing protein 0.0026 0.0079 0.0136
Trypanosoma cruzi phosphatidylinositol-4-phosphate 5-kinase, putative 0.0058 0.0426 0.0928
Schistosoma mansoni hypothetical protein 0.0044 0.0273 0.0273
Toxoplasma gondii phosphofructokinase PFKII 0.003 0.0121 0.0248
Echinococcus multilocularis polybromo 1 0.0022 0.0026 0.0015
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0053 0.0375 0.081
Brugia malayi jmjC domain containing protein 0.005 0.0337 0.0436
Loa Loa (eye worm) hypothetical protein 0.0037 0.0197 0.0254
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0053 0.0375 0.0698
Trichomonas vaginalis rotamase, putative 0.0072 0.0588 0.0567
Schistosoma mansoni aldehyde dehydrogenase 0.006 0.0456 0.0457
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.045 0.4755 1
Loa Loa (eye worm) hypothetical protein 0.0037 0.0197 0.0254
Plasmodium falciparum transcriptional regulatory protein sir2a 0.0053 0.0373 0.0917
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0085 0.0731 0.0733
Leishmania major phosphatidylinositol-4-phosphate 5-kinase-like protein 0.0058 0.0426 0.0935
Schistosoma mansoni flap endonuclease-1 0.0027 0.0085 0.0085
Brugia malayi Matrixin family protein 0.0046 0.03 0.0388
Schistosoma mansoni hypothetical protein 0.009 0.078 0.0782
Leishmania major 4-coumarate:coa ligase-like protein 0.0053 0.0375 0.0816
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0091 0.0788 0.1781
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0071 0.0569 0.0545
Echinococcus multilocularis cpg binding protein 0.0141 0.1341 0.1331
Leishmania major 4-coumarate:coa ligase-like protein 0.0053 0.0375 0.0816
Plasmodium falciparum NLI interacting factor-like phosphatase, putative 0.0026 0.0079 0.0136
Echinococcus multilocularis bloom syndrome protein 0.0133 0.1253 0.1243
Echinococcus granulosus polycomb protein SCMH1 0.0054 0.0389 0.0379
Echinococcus multilocularis PHD finger protein rhinoceros 0.0033 0.0155 0.0145
Mycobacterium leprae conserved hypothetical protein 0.0037 0.0197 0.0319
Leishmania major phosphopantetheinyl transferase-like protein 0.0024 0.0053 0.006
Leishmania major hypothetical protein, conserved 0.0026 0.0079 0.012
Brugia malayi Matrix metalloprotease, N-terminal domain containing protein 0.0023 0.0046 0.006
Loa Loa (eye worm) hypothetical protein 0.0098 0.0868 0.1123
Onchocerca volvulus 0.0042 0.0256 0.0319
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0053 0.0373 0.0351
Mycobacterium ulcerans 6-phosphofructokinase 0.0112 0.1021 0.207
Trichomonas vaginalis dullard protein, putative 0.0026 0.0079 0.0055

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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