Detailed information for compound 1267009

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 312.368 | Formula: C20H16N4
  • H donors: 1 H acceptors: 3 LogP: 4.16 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: Cc1ccc2c(c1)C(=NNC(=N2)c1ccccc1)c1ccncc1
  • InChi: 1S/C20H16N4/c1-14-7-8-18-17(13-14)19(15-9-11-21-12-10-15)23-24-20(22-18)16-5-3-2-4-6-16/h2-13H,1H3,(H,22,24)
  • InChiKey: ZCANMNAKUGPLSC-UHFFFAOYSA-N  


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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens ATPase family, AAA domain containing 5 Starlite/ChEMBL No references
Homo sapiens Niemann-Pick disease, type C1 Starlite/ChEMBL No references
Photinus pyralis Luciferin 4-monooxygenase Starlite/ChEMBL No references
Homo sapiens RAB9A, member RAS oncogene family Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Leishmania mexicana 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans fatty-acid-CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania mexicana 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma japonicum Niemann-Pick C1 protein precursor, putative Get druggable targets OG5_128206 All targets in OG5_128206
Plasmodium falciparum acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Entamoeba histolytica acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania donovani 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Brugia malayi Niemann-Pick C1 protein precursor Get druggable targets OG5_128206 All targets in OG5_128206
Brugia malayi AMP-binding enzyme family protein Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus granulosus Niemann Pick C1 protein Get druggable targets OG5_128206 All targets in OG5_128206
Candida albicans potential membrane protein similar to S. cerevisiae NCR1 (YPL006W) and human NPC1 late endosomal protein involved in sterol home Get druggable targets OG5_128206 All targets in OG5_128206
Leishmania major 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128206 All targets in OG5_128206
Mycobacterium ulcerans fatty-acid-CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania donovani 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus multilocularis Niemann Pick C1 protein Get druggable targets OG5_128206 All targets in OG5_128206
Entamoeba histolytica Niemann-Pick C1 protein, putative Get druggable targets OG5_128206 All targets in OG5_128206
Plasmodium vivax acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Onchocerca volvulus Get druggable targets OG5_126609 All targets in OG5_126609
Brugia malayi AMP-binding enzyme family protein Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus granulosus Niemann Pick C1 protein Get druggable targets OG5_128206 All targets in OG5_128206
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Brugia malayi AMP-binding enzyme family protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Entamoeba histolytica acyl-coA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128206 All targets in OG5_128206
Schistosoma japonicum ko:K07003 Niemann Pick type C1, putative Get druggable targets OG5_128206 All targets in OG5_128206
Echinococcus granulosus expressed conserved protein Get druggable targets OG5_128206 All targets in OG5_128206
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium berghei acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma japonicum Niemann-Pick C1 protein precursor, putative Get druggable targets OG5_128206 All targets in OG5_128206
Echinococcus multilocularis expressed conserved protein Get druggable targets OG5_128206 All targets in OG5_128206
Leishmania major 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania braziliensis 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans long-chain fatty-acid CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Entamoeba histolytica acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium knowlesi acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium yoelii peroxisomal-coenzyme a synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core Get druggable targets OG5_139225 All targets in OG5_139225
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania mexicana 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma mansoni niemann-pick C1 (NPC1) Get druggable targets OG5_128206 All targets in OG5_128206
Leishmania major 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus multilocularis Niemann Pick C1 protein Get druggable targets OG5_128206 All targets in OG5_128206
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 18.3 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 593 aa 22.1 %
Trichomonas vaginalis long-chain-fatty-acid CoA ligase, putative Luciferin 4-monooxygenase   550 aa 466 aa 21.7 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD25 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 475 aa 21.1 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD28 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 504 aa 22.6 %
Mycobacterium ulcerans putative fatty-acid--CoA ligase Luciferin 4-monooxygenase   550 aa 576 aa 20.8 %
Loa Loa (eye worm) AMP-binding enzyme family protein Luciferin 4-monooxygenase   550 aa 489 aa 23.3 %
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF Luciferin 4-monooxygenase   550 aa 558 aa 20.1 %
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD34 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 537 aa 20.9 %
Schistosoma mansoni FAA1 Long-chain-fatty-acid--CoA ligase 1 Luciferin 4-monooxygenase   550 aa 494 aa 26.3 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD32 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase). Also shown to have acyl-ACP ligase activity. Luciferin 4-monooxygenase   550 aa 487 aa 22.4 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 539 aa 19.1 %
Leishmania infantum long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 500 aa 23.4 %
Schistosoma japonicum ko:K08745 solute carrier family 27 (fatty acid transporter), member 1, putative Luciferin 4-monooxygenase   550 aa 501 aa 24.6 %
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) Luciferin 4-monooxygenase   550 aa 535 aa 23.2 %
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase Luciferin 4-monooxygenase   550 aa 536 aa 24.4 %
Echinococcus granulosus long chain fatty acid coenzyme A ligase 1 Luciferin 4-monooxygenase   550 aa 452 aa 26.1 %
Brugia malayi AMP-binding enzyme family protein Luciferin 4-monooxygenase   550 aa 544 aa 21.5 %
Candida albicans similar to S. cerevisiae FAT1 (YBR041W) fatty acid transporter and very long-chain fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 496 aa 24.2 %
Candida albicans similar to S. cerevisiae FAT1 (YBR041W) fatty acid transporter and very long-chain fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 496 aa 24.2 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD29 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 529 aa 22.3 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 558 aa 20.4 %
Cryptosporidium hominis acetyl-CoenzymeA synthetase (acetate--coa ligase) (acyl-activating enzyme) Luciferin 4-monooxygenase   550 aa 549 aa 22.6 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD29 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 617 aa 22.2 %
Echinococcus multilocularis long chain fatty acid transport protein 4 Luciferin 4-monooxygenase   550 aa 476 aa 22.3 %
Trypanosoma cruzi fatty acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 482 aa 24.7 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 539 aa 19.1 %
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase, FadD11 Luciferin 4-monooxygenase   550 aa 492 aa 24.6 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 499 aa 19.2 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 539 aa 22.1 %
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 1 Luciferin 4-monooxygenase   550 aa 443 aa 26.4 %
Trypanosoma congolense fatty acyl CoA synthetase 2, putative Luciferin 4-monooxygenase   550 aa 500 aa 22.4 %
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 480 aa 22.5 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 22.1 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 582 aa 22.3 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 538 aa 21.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 535 aa 22.6 %
Neospora caninum acetyl-coenzyme a synthetase, putative Luciferin 4-monooxygenase   550 aa 549 aa 20.9 %
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase Luciferin 4-monooxygenase   550 aa 509 aa 21.8 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 517 aa 24.8 %
Neospora caninum Short-chain dehydrogenase/reductase SDR, related Luciferin 4-monooxygenase   550 aa 518 aa 19.1 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 545 aa 24.9 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD26 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 560 aa 21.4 %
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 5 Luciferin 4-monooxygenase   550 aa 458 aa 25.5 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 576 aa 19.8 %
Cryptosporidium parvum acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 460 aa 25.7 %
Theileria parva long-chain fatty acid CoA ligase, putative Luciferin 4-monooxygenase   550 aa 507 aa 23.5 %
Leishmania major long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 482 aa 23.2 %
Trichomonas vaginalis AMP dependent ligase, putative Luciferin 4-monooxygenase   550 aa 445 aa 26.1 %
Mycobacterium ulcerans fatty-acid-CoA ligase FadD9 Luciferin 4-monooxygenase   550 aa 463 aa 21.8 %
Echinococcus granulosus long chain fatty acid coenzyme A ligase 5 Luciferin 4-monooxygenase   550 aa 458 aa 25.8 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 494 aa 24.3 %
Toxoplasma gondii type I fatty acid synthase, putative Luciferin 4-monooxygenase   550 aa 514 aa 19.8 %
Echinococcus granulosus long chain fatty acid transport protein 4 Luciferin 4-monooxygenase   550 aa 476 aa 22.3 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 535 aa 21.7 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 554 aa 24.4 %
Leishmania mexicana acetyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 559 aa 20.6 %
Babesia bovis fatty acyl-CoA synthetase family protein Luciferin 4-monooxygenase   550 aa 461 aa 23.4 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD21 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 586 aa 24.4 %
Onchocerca volvulus Luciferin 4-monooxygenase   550 aa 502 aa 24.9 %
Cryptosporidium parvum putative long chain fatty acyl CoA synthetase having a signal peptide Luciferin 4-monooxygenase   550 aa 472 aa 24.8 %
Mycobacterium ulcerans non-ribosomal peptide synthetase Luciferin 4-monooxygenase   550 aa 541 aa 22.4 %
Trypanosoma brucei gambiense fatty acyl CoA synthetase 3 Luciferin 4-monooxygenase   550 aa 491 aa 23.6 %
Mycobacterium leprae Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 461 aa 22.3 %
Toxoplasma gondii propionate-CoA ligase Luciferin 4-monooxygenase   550 aa 550 aa 21.1 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 531 aa 19.0 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 539 aa 22.1 %
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 Luciferin 4-monooxygenase   550 aa 493 aa 22.1 %
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase FadD15 Luciferin 4-monooxygenase   550 aa 482 aa 24.3 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 507 aa 20.9 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD24 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 526 aa 21.9 %
Mycobacterium leprae FATTY-ACID-CoA LIGASE FADD26 (FATTY-ACID-COA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Luciferin 4-monooxygenase   550 aa 533 aa 22.7 %
Trypanosoma brucei fatty acyl CoA synthetase 3 Luciferin 4-monooxygenase   550 aa 491 aa 23.6 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.6 %
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative Luciferin 4-monooxygenase   550 aa 480 aa 21.5 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 554 aa 22.9 %
Schistosoma japonicum ko:K01897 long-chain fatty-acid-CoA ligase [EC6.2.1.3], putative Luciferin 4-monooxygenase   550 aa 541 aa 22.4 %
Mycobacterium tuberculosis Probable acyl-CoA ligase FadD31 (acyl-CoA synthetase) (acyl-CoA synthase) Luciferin 4-monooxygenase   550 aa 592 aa 20.4 %
Onchocerca volvulus Matrilysin homolog Luciferin 4-monooxygenase   550 aa 466 aa 24.2 %
Leishmania mexicana long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 483 aa 23.8 %
Trichomonas vaginalis AMP dependent CoA ligase, putative Luciferin 4-monooxygenase   550 aa 527 aa 25.0 %
Trypanosoma cruzi fatty acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 480 aa 25.2 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.4 %
Onchocerca volvulus Luciferin 4-monooxygenase   550 aa 487 aa 23.8 %
Trypanosoma brucei gambiense fatty acyl CoA synthetase 4, putative Luciferin 4-monooxygenase   550 aa 497 aa 23.7 %
Trichomonas vaginalis long-chain-fatty-acid CoA ligase, putative Luciferin 4-monooxygenase   550 aa 490 aa 23.3 %
Brugia malayi AMP-binding enzyme family protein Luciferin 4-monooxygenase   550 aa 497 aa 24.7 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD32 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 442 aa 23.5 %
Dictyostelium discoideum acetyl-CoA ligase Luciferin 4-monooxygenase   550 aa 549 aa 22.2 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 543 aa 24.5 %
Trichomonas vaginalis AMP dependent CoA ligase, putative Luciferin 4-monooxygenase   550 aa 524 aa 24.0 %
Babesia bovis long-chain acyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 445 aa 21.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 18.3 %
Mycobacterium leprae Probable long-chain-fatty-acid-CoA ligase FadD15 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Luciferin 4-monooxygenase   550 aa 484 aa 23.3 %
Trypanosoma cruzi fatty acyl CoA synthetase 2, putative Luciferin 4-monooxygenase   550 aa 495 aa 22.6 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 526 aa 22.4 %
Dictyostelium discoideum fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 462 aa 23.8 %
Mycobacterium leprae PROBABLE FATTY-ACID--CoA LIGASE FADD21 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Luciferin 4-monooxygenase   550 aa 565 aa 22.8 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 543 aa 24.5 %
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) Luciferin 4-monooxygenase   550 aa 509 aa 22.6 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD28 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 484 aa 20.5 %
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative Luciferin 4-monooxygenase   550 aa 494 aa 23.9 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 497 aa 19.3 %
Candida albicans similar to S. cerevisiae FAA4 (YMR246W) long-chain fatty acid--CoA synthetase Luciferin 4-monooxygenase   550 aa 478 aa 23.4 %
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE Luciferin 4-monooxygenase   550 aa 502 aa 22.5 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 538 aa 21.8 %
Mycobacterium ulcerans fatty-acid-CoA ligase FadD11 Luciferin 4-monooxygenase   550 aa 498 aa 23.5 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 530 aa 23.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 478 aa 21.1 %
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 1 Luciferin 4-monooxygenase   550 aa 459 aa 27.0 %
Entamoeba histolytica acyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 446 aa 22.0 %
Schistosoma japonicum ko:K01897 long-chain fatty-acid-CoA ligase [EC6.2.1.3], putative Luciferin 4-monooxygenase   550 aa 466 aa 27.3 %
Trichomonas vaginalis antibiotic synthetase, putative Luciferin 4-monooxygenase   550 aa 581 aa 21.2 %
Leishmania donovani long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 500 aa 23.4 %
Trichomonas vaginalis antibiotic synthetase, putative Luciferin 4-monooxygenase   550 aa 577 aa 22.2 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 522 aa 19.9 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.4 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 493 aa 20.7 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.6 %
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein Luciferin 4-monooxygenase   550 aa 476 aa 22.5 %
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative Luciferin 4-monooxygenase   550 aa 476 aa 20.8 %
Dictyostelium discoideum fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 501 aa 24.4 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 22.1 %
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 505 aa 28.1 %
Plasmodium falciparum ras-related protein Rab-5B RAB9A, member RAS oncogene family 201 aa 165 aa 30.9 %
Cryptosporidium parvum acetyl-coenzyme A synthetase Luciferin 4-monooxygenase   550 aa 545 aa 22.8 %
Trichomonas vaginalis AMP dependent CoA ligase, putative Luciferin 4-monooxygenase   550 aa 492 aa 23.6 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 550 aa 20.9 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 601 aa 22.5 %
Cryptosporidium hominis acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 460 aa 26.1 %
Onchocerca volvulus Lysine-specific histone demethylase 1A homolog Luciferin 4-monooxygenase   550 aa 550 aa 22.5 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 522 aa 19.9 %
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase FadD15 Luciferin 4-monooxygenase   550 aa 484 aa 26.0 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 476 aa 23.5 %
Leishmania braziliensis acetyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 603 aa 22.6 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD23 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 542 aa 23.8 %
Leishmania braziliensis long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 496 aa 22.8 %
Leishmania braziliensis acetyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 596 aa 21.1 %
Leishmania braziliensis long-chain-fatty-acid-CoA ligase, putative Luciferin 4-monooxygenase   550 aa 504 aa 25.6 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 463 aa 23.5 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis CMGC family protein kinase 0.0092 0.0089 0.0786
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0135 0.0188 0.0534
Loa Loa (eye worm) hypothetical protein 0.0062 0.002 0.002
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0072 0.0044 0.0117
Entamoeba histolytica protein kinase domain containing protein 0.0545 0.1135 1
Trypanosoma cruzi cdc2-related kinase 1 0.0164 0.0257 0.2262
Echinococcus multilocularis peroxidasin 0.007 0.0039 0.0105
Schistosoma mansoni serine/threonine protein kinase 0.0197 0.0333 0.0943
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0309 0.059 0.5198
Schistosoma mansoni protein kinase 0.0192 0.032 0.0907
Loa Loa (eye worm) SH2 domain-containing protein 0.0062 0.002 0.002
Trichomonas vaginalis AGC family protein kinase 0.0092 0.009 0.0792
Onchocerca volvulus 0.0062 0.002 0.0061
Echinococcus granulosus mitogen activated protein kinase 14 0.0159 0.0243 0.0689
Brugia malayi Protein kinase domain containing protein 0.0116 0.0146 0.0146
Onchocerca volvulus Suppressor of cytokine signaling 7 homolog 0.0062 0.002 0.0062
Loa Loa (eye worm) AGC/PKA protein kinase 0.0159 0.0244 0.0244
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0159 0.0244 0.2152
Loa Loa (eye worm) hypothetical protein 0.0079 0.0059 0.0059
Loa Loa (eye worm) hypothetical protein 0.0062 0.002 0.002
Entamoeba histolytica hypothetical protein 0.0309 0.059 0.5198
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0194 0.0326 0.0923
Brugia malayi protein unc-22 0.0071 0.0042 0.0042
Onchocerca volvulus 0.0092 0.0089 0.0273
Brugia malayi Immunoglobulin I-set domain containing protein 0.007 0.0038 0.0038
Trichomonas vaginalis conserved hypothetical protein 0.0155 0.0235 0.2068
Schistosoma mansoni serine/threonine protein kinase 0.0309 0.059 0.1673
Loa Loa (eye worm) hypothetical protein 0.007 0.0038 0.0038
Echinococcus granulosus tyrosine protein kinase Src64B 0.0194 0.0326 0.0923
Brugia malayi Immunoglobulin I-set domain containing protein 0.007 0.0038 0.0038
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.007 0.0038 0.0038
Schistosoma mansoni protein kinase 0.0102 0.0112 0.0318
Echinococcus multilocularis nervana 2 0.0066 0.003 0.0081
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.0058 0.0011 0.0011
Loa Loa (eye worm) G protein-coupled receptor kinase 1 0.0157 0.0241 0.0241
Schistosoma mansoni tyrosine kinase 0.0924 0.2007 0.5691
Loa Loa (eye worm) hypothetical protein 0.007 0.0038 0.0038
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0518 0.1071 0.9434
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0082 0.0068 0.0595
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0068 0.0035 0.0035
Schistosoma mansoni serine/threonine-protein kinase 0.0108 0.0128 0.0363
Giardia lamblia Kinase, CMGC CDK 0.0164 0.0257 0.2262
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0085 0.0073 0.0073
Schistosoma mansoni serine/threonine protein kinase 0.0219 0.0383 0.1087
Echinococcus granulosus Immunoglobulin 0.0135 0.0188 0.0534
Echinococcus multilocularis roundabout 2 0.0207 0.0354 0.095
Giardia lamblia Kinase, CMGC GSK 0.0545 0.1135 1
Giardia lamblia Kinase, AGC PKA 0.0103 0.0116 0.1019
Trichomonas vaginalis CMGC family protein kinase 0.0164 0.0257 0.2262
Echinococcus multilocularis cyclin dependent kinase 0.0164 0.0257 0.0688
Entamoeba histolytica protein kinase, putative 0.0074 0.0047 0.0417
Entamoeba histolytica protein kinase, putative 0.0518 0.1071 0.9434
Brugia malayi Protein kinase domain containing protein 0.0098 0.0104 0.0104
Loa Loa (eye worm) TK/FER protein kinase 0.0115 0.0142 0.0142
Brugia malayi Furin-like cysteine rich region family protein 0.1583 0.3527 0.3527
Giardia lamblia Kinase, STE STE20 0.0114 0.0141 0.1245
Giardia lamblia Kinase, CAMK CAMKL 0.0091 0.0086 0.0762
Echinococcus granulosus CDC7 cell division cycle 7 0.0092 0.0089 0.0253
Echinococcus granulosus serine:threonine protein kinase Chk2 0.0074 0.0047 0.0134
Loa Loa (eye worm) hypothetical protein 0.0137 0.0194 0.0194
Entamoeba histolytica hypothetical protein 0.0134 0.0187 0.1644
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.1308 0.2893 0.7756
Echinococcus granulosus roundabout 2 0.0207 0.0354 0.1004
Echinococcus granulosus tyrosine protein kinase ABL1 0.0314 0.0603 0.1709
Schistosoma mansoni tyrosine kinase 0.0871 0.1885 0.5345
Entamoeba histolytica casein kinase, putative 0.0102 0.0112 0.0989
Echinococcus granulosus tyrosine protein kinase Blk 0.0171 0.0273 0.0773
Echinococcus granulosus titin 0.0071 0.0042 0.0119
Echinococcus granulosus tyrosine protein kinase Fyn 0.0194 0.0326 0.0923
Brugia malayi Variant SH3 domain containing protein 0.0095 0.0096 0.0096
Loa Loa (eye worm) hypothetical protein 0.025 0.0454 0.0454
Echinococcus multilocularis Glutaredoxin protein 5 0.0066 0.003 0.0081
Trichomonas vaginalis TKL family protein kinase 0.0054 0.0001 0.001
Brugia malayi intracellular kinase 0.0545 0.1135 0.1135
Trichomonas vaginalis mitogen-activated protein kinase kinase kinase 3, MAPKKK3, MEKK3, putative 0.0058 0.0011 0.01
Echinococcus multilocularis signal transduction protein lnk realted 0.0062 0.002 0.0054
Trypanosoma cruzi casein kinase, putative 0.0113 0.0138 0.1216
Loa Loa (eye worm) CAMK/PIM protein kinase 0.1248 0.2754 0.2754
Echinococcus multilocularis SH2 domain containing adapter protein F 0.0062 0.002 0.0054
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0135 0.0188 0.0505
Schistosoma mansoni tyrosine kinase 0.0244 0.044 0.1247
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0159 0.0244 0.2152
Schistosoma mansoni serine/threonine protein kinase 0.0174 0.0278 0.0788
Schistosoma mansoni serine/threonine protein kinase 0.0159 0.0244 0.0692
Trichomonas vaginalis CMGC family protein kinase 0.0086 0.0076 0.0669
Onchocerca volvulus 0.0115 0.0142 0.0436
Giardia lamblia Kinase, NEK 0.0136 0.0192 0.1693
Echinococcus granulosus defective proboscis extension response 0.0135 0.0188 0.0534
Echinococcus granulosus tyrosine protein kinase Src42A 0.0118 0.015 0.0426
Brugia malayi SH2 domain containing protein 0.0062 0.002 0.002
Echinococcus granulosus hypothetical protein 0.0062 0.002 0.0057
Trichomonas vaginalis CAMK family protein kinase 0.0082 0.0068 0.0595
Loa Loa (eye worm) TK/ALK protein kinase 0.0342 0.0666 0.0666
Brugia malayi Variant SH3 domain containing protein 0.0085 0.0073 0.0073
Leishmania major protein kinase A catalytic subunit isoform 2 0.0159 0.0244 0.2152
Echinococcus multilocularis Niemann Pick C1 protein 0.017 0.0269 0.0722
Loa Loa (eye worm) hypothetical protein 0.0062 0.002 0.002
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0122 0.0159 0.0426
Loa Loa (eye worm) hypothetical protein 0.0204 0.0349 0.0349
Trypanosoma cruzi casein kinase II, putative 0.0102 0.0112 0.0989
Brugia malayi Sex muscle abnormal protein 5 0.0085 0.0073 0.0073
Entamoeba histolytica protein kinase, putative 0.0053 0.0001 0.0006
Schistosoma mansoni septate junction protein 0.007 0.0038 0.0109
Schistosoma mansoni serine/threonine-protein kinase 0.0108 0.0128 0.0363
Loa Loa (eye worm) hypothetical protein 0.007 0.0038 0.0038
Toxoplasma gondii CMGC kinase, CK2 family 0.0102 0.0112 0.0989
Schistosoma mansoni serine/threonine protein kinase 0.0164 0.0257 0.0728
Brugia malayi putative serine/threonine kinase SADA gamma 0.0082 0.0068 0.0068
Schistosoma mansoni serine/threonine protein kinase 0.0058 0.0011 0.0032
Entamoeba histolytica protein kinase, putative 0.0099 0.0106 0.0931
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0171 0.0272 0.0272
Echinococcus granulosus hypothetical protein 0.0126 0.0168 0.0475
Onchocerca volvulus 0.0076 0.0053 0.0161
Schistosoma mansoni serine/threonine protein kinase 0.0164 0.0257 0.0728
Loa Loa (eye worm) hypothetical protein 0.0115 0.0142 0.0142
Schistosoma mansoni serine/threonine protein kinase 0.0106 0.0121 0.0343
Entamoeba histolytica leucine-rich repeat domain-containing protein 0.0053 0.0001 0.0006
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0085 0.0074 0.0208
Brugia malayi Variant SH3 domain containing protein 0.0085 0.0073 0.0073
Toxoplasma gondii AGC kinase 0.0159 0.0244 0.2152
Plasmodium falciparum casein kinase 2, alpha subunit 0.0102 0.0112 0.0989
Loa Loa (eye worm) TK/KIN16 protein kinase 0.1611 0.3591 0.3591
Echinococcus multilocularis raf serine:threonine protein kinase 0.0086 0.0076 0.0204
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0164 0.0257 0.0257
Brugia malayi Protein kinase domain containing protein 0.0115 0.0142 0.0142
Echinococcus granulosus roundabout 2 0.0072 0.0044 0.0124
Echinococcus multilocularis mitogen activated protein kinase 11 0.0159 0.0243 0.0652
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0127 0.0171 0.0484
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0545 0.1135 0.3043
Schistosoma mansoni roundabout 0.007 0.0038 0.0109
Trichomonas vaginalis CAMK family protein kinase 0.0082 0.0068 0.0595
Schistosoma mansoni serine/threonine protein kinase 0.0116 0.0146 0.0414
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0545 0.1135 0.3218
Brugia malayi Protein kinase domain containing protein 0.0092 0.0089 0.0089
Trypanosoma cruzi casein kinase, putative 0.0113 0.0138 0.1216
Brugia malayi Protein kinase domain containing protein 0.0115 0.0142 0.0142
Schistosoma mansoni serine/threonine kinase 0.0116 0.0146 0.0414
Brugia malayi Immunoglobulin I-set domain containing protein 0.007 0.0038 0.0038
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.0385 0.0765 0.205
Entamoeba histolytica tyrosin kinase, putative 0.0056 0.0007 0.0062
Brugia malayi Protein kinase domain containing protein 0.0752 0.1611 0.1611
Echinococcus granulosus casein kinase I alpha 0.0113 0.0138 0.0391
Loa Loa (eye worm) hypothetical protein 0.0129 0.0176 0.0176
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0062 0.002 0.0054
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0062 0.002 0.0057
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0219 0.0383 0.1087
Leishmania major protein kinase, putative 0.009 0.0085 0.0752
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0159 0.0244 0.0244
Trichomonas vaginalis CAMK family protein kinase 0.0082 0.0068 0.0595
Echinococcus multilocularis CDC7 cell division cycle 7 0.0092 0.0089 0.0239
Toxoplasma gondii aurora kinase 0.0518 0.1071 0.9434
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0062 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0062 0.0022 0.0022
Trypanosoma brucei protein kinase, putative 0.0094 0.0095 0.0836
Trichomonas vaginalis CMGC family protein kinase 0.0086 0.0076 0.0669
Loa Loa (eye worm) hypothetical protein 0.0062 0.002 0.002
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0754 0.1616 0.4332
Loa Loa (eye worm) TK/FER protein kinase 0.0115 0.0142 0.0142
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0136 0.0192 0.1693
Trichomonas vaginalis STE family protein kinase 0.0114 0.0141 0.1245
Trypanosoma brucei cdc2-related kinase 1 0.0164 0.0257 0.2262
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0309 0.059 0.5198
Schistosoma mansoni serine/threonine protein kinase 0.0518 0.1071 0.3035
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0159 0.0243 0.2143
Entamoeba histolytica protein kinase, putative 0.0188 0.0311 0.2738
Echinococcus granulosus peroxidasin 0.007 0.0039 0.0111
Echinococcus granulosus [G-protein-coupledreceptor] kinase 0.0157 0.0241 0.0683
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0135 0.0188 0.0534
Brugia malayi Protein kinase domain containing protein 0.0115 0.0142 0.0142
Loa Loa (eye worm) TK/FER protein kinase 0.0115 0.0142 0.0142
Loa Loa (eye worm) hypothetical protein 0.0067 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0127 0.0171 0.0171
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0197 0.0333 0.0943
Schistosoma mansoni tyrosine kinase 0.0253 0.046 0.1305
Echinococcus multilocularis neurotracting:lsamp:neurotrimin:obcam 0.007 0.0038 0.0103
Trichomonas vaginalis CAMK family protein kinase 0.0082 0.0068 0.0595
Echinococcus granulosus 3'partial|serine:threonine protein kinase PAK 2 0.0134 0.0187 0.0529
Entamoeba histolytica serine/threonine protein kinase, putative 0.0082 0.0068 0.0595
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0084 0.0071 0.0201
Trypanosoma cruzi polo-like protein kinase, putative 0.0219 0.0383 0.3378
Echinococcus multilocularis PAK box P21 Rho binding 0.0171 0.0272 0.0729
Onchocerca volvulus Suppressor of cytokine signaling at 36E homolog 0.0062 0.002 0.0062
Echinococcus granulosus Niemann Pick C1 protein 0.017 0.0269 0.0764
Trichomonas vaginalis STE family protein kinase 0.0114 0.0141 0.1245
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0309 0.059 0.059
Trichomonas vaginalis CMGC family protein kinase 0.0086 0.0076 0.0669
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0127 0.0171 0.0458
Onchocerca volvulus 0.0112 0.0135 0.0413
Echinococcus granulosus serine/threonine protein kinase 0.0108 0.0128 0.0363
Echinococcus granulosus casein kinase I delta 0.0113 0.0138 0.0391
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0501 0.1032 0.2766
Echinococcus granulosus cyclin dependent kinase 7 0.0117 0.0148 0.042
Echinococcus multilocularis cyclin dependent kinase 19 0.0174 0.0278 0.0745
Loa Loa (eye worm) hypothetical protein 0.0135 0.0188 0.0188
Brugia malayi Immunoglobulin I-set domain containing protein 0.0072 0.0044 0.0044
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0084 0.0071 0.0071
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0116 0.0144 0.0144
Echinococcus multilocularis mitogen activated protein kinase 14 0.0159 0.0243 0.0652
Entamoeba histolytica protein kinase, putative 0.0309 0.059 0.5198
Onchocerca volvulus 0.1437 0.3189 0.9762
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0085 0.0073 0.0073
Loa Loa (eye worm) TKL/LRRK protein kinase 0.0098 0.0104 0.0104
Echinococcus multilocularis NCK adaptor protein 0.0085 0.0073 0.0196
Trypanosoma cruzi p21-activated kinase 3, putative 0.0058 0.0011 0.01
Giardia lamblia Kinase, STE STE20 0.0192 0.032 0.282
Brugia malayi serine/threonine-protein kinase 6 0.0518 0.1071 0.1071
Echinococcus multilocularis serine:threonine protein kinase 0.0076 0.0053 0.0143
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0072 0.0044 0.0044
Leishmania major protein kinase, putative 0.0087 0.0078 0.0687
Loa Loa (eye worm) hypothetical protein 0.0134 0.0186 0.0186
Giardia lamblia Kinase, CAMK CAMKL 0.0091 0.0086 0.0762
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0156 0.0237 0.0237
Echinococcus granulosus serine:threonine kinase SAD 1 0.0082 0.0068 0.0191
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0545 0.1135 1
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0194 0.0326 0.0873
Trichomonas vaginalis AGC family protein kinase 0.0518 0.1071 0.9434
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.1442 0.3202 0.3202
Loa Loa (eye worm) AUR protein kinase 0.0518 0.1071 0.1071
Schistosoma mansoni suppressor of cytokine signaling 0.0062 0.002 0.0057
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0194 0.0326 0.0873
Plasmodium vivax unspecified product 0.0102 0.0112 0.0989
Echinococcus multilocularis tyrosine protein kinase otk 0.007 0.0038 0.0103
Schistosoma mansoni serine/threonine protein kinase 0.0127 0.0171 0.0484
Leishmania major casein kinase, putative 0.0113 0.0138 0.1216
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0163 0.0253 0.2228
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0545 0.1135 0.3218
Trichomonas vaginalis STE family protein kinase 0.0192 0.032 0.282
Brugia malayi Protein kinase domain containing protein 0.0084 0.0071 0.0071
Brugia malayi SH2 domain containing protein 0.0062 0.002 0.002
Onchocerca volvulus 0.14 0.3104 0.9501
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0086 0.0076 0.0669
Loa Loa (eye worm) hypothetical protein 0.0272 0.0505 0.0505
Loa Loa (eye worm) TK/FER protein kinase 0.0115 0.0142 0.0142
Echinococcus multilocularis myosin iiia 0.0087 0.0078 0.0209
Brugia malayi serine/threonine kinase 12 0.0518 0.1071 0.1071
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0072 0.0044 0.0117
Brugia malayi Stress-activated protein kinase jnk-1 0.0501 0.1032 0.1032
Entamoeba histolytica PH domain containing protein kinase, putative 0.0164 0.0256 0.226
Trichomonas vaginalis AGC family protein kinase 0.0159 0.0244 0.2152
Schistosoma mansoni ephrin receptor 0.0115 0.0142 0.0403
Trichomonas vaginalis AGC family protein kinase 0.0188 0.0311 0.2738
Onchocerca volvulus Tyrosine kinase homolog 0.147 0.3267 1
Echinococcus multilocularis cyclin dependent kinase 7 0.0117 0.0148 0.0397
Echinococcus granulosus contactin 0.0072 0.0044 0.0124
Schistosoma mansoni neuroglian 0.0072 0.0044 0.0124
Echinococcus multilocularis casein kinase I delta 0.0113 0.0138 0.037
Echinococcus granulosus mitogen activated protein kinase 3 0.0086 0.0076 0.0215
Schistosoma mansoni serine/threonine protein kinase 0.0086 0.0076 0.0215
Brugia malayi hypothetical protein 0.0115 0.0142 0.0142
Loa Loa (eye worm) AGC/PKN protein kinase 0.0116 0.0146 0.0146
Echinococcus multilocularis serine:threonine protein kinase 3 0.0253 0.046 0.1233
Entamoeba histolytica protein kinase, putative 0.0545 0.1135 1
Brugia malayi casein kinase 1, delta 0.0113 0.0138 0.0138
Loa Loa (eye worm) CMGC/CDK/CDK8 protein kinase 0.0174 0.0278 0.0278
Leishmania major protein kinase, putative 0.0163 0.0253 0.2228
Entamoeba histolytica hypothetical protein 0.0054 0.0001 0.001
Trypanosoma brucei protein kinase, putative 0.009 0.0085 0.0752
Echinococcus multilocularis tyrosine kinase 0.0115 0.0142 0.0382
Entamoeba histolytica protein kinase domain containing protein 0.0056 0.0007 0.0062
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0092 0.009 0.009
Trichomonas vaginalis CMGC family protein kinase 0.0086 0.0076 0.0669
Trichomonas vaginalis CMGC family protein kinase 0.0092 0.0089 0.0786
Trichomonas vaginalis CMGC family protein kinase 0.0164 0.0257 0.2262
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0113 0.0138 0.0138
Trichomonas vaginalis CMGC family protein kinase 0.0102 0.0112 0.0989
Schistosoma mansoni serine/threonine protein kinase 0.0199 0.0336 0.0951
Schistosoma mansoni serine/threonine protein kinase 0.0082 0.0068 0.0191
Echinococcus multilocularis protein kinase c iota type 0.0229 0.0406 0.1088
Brugia malayi STAT protein, DNA binding domain containing protein 0.0062 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0062 0.002 0.002
Loa Loa (eye worm) P21-Rho-binding domain-containing protein 0.0134 0.0187 0.0187
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0106 0.0121 0.0325
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0164 0.0257 0.0728
Schistosoma mansoni serine/threonine protein kinase 0.0117 0.0148 0.042
Toxoplasma gondii casein kinase I 0.0113 0.0138 0.1216
Schistosoma mansoni serine/threonine protein kinase 0.0159 0.0244 0.0692
Entamoeba histolytica casein kinase, putative 0.0113 0.0138 0.1216
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.0062 0.002 0.0057
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0151 0.0225 0.0225
Trypanosoma cruzi casein kinase, putative 0.0113 0.0138 0.1216
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0159 0.0243 0.2143
Schistosoma mansoni nephrin 0.0169 0.0267 0.0757
Trichomonas vaginalis AGC family protein kinase 0.0188 0.0311 0.2738
Trichomonas vaginalis AGC family protein kinase 0.0084 0.0071 0.0624
Echinococcus granulosus hemicentin 1 0.007 0.0038 0.0109
Echinococcus granulosus neural Wiskott Aldrich syndrome protein 0.0134 0.0187 0.0529
Trypanosoma cruzi cdc2-related kinase 3 0.0164 0.0257 0.2262
Schistosoma mansoni serine/threonine protein kinase 0.0385 0.0765 0.2168
Echinococcus multilocularis cyclin dependent kinase 9 0.0092 0.0091 0.0243
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0159 0.0244 0.2152
Schistosoma mansoni adapter molecule crk 0.0085 0.0073 0.0208
Schistosoma mansoni serine/threonine protein kinase 0.0116 0.0146 0.0414
Echinococcus granulosus tyrosine kinase 0.0171 0.0273 0.0773
Echinococcus multilocularis Immunoglobulin 0.0135 0.0188 0.0505
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0062 0.002 0.002
Trichomonas vaginalis CAMK family protein kinase 0.0082 0.0068 0.0595
Echinococcus granulosus casein kinase ii subunit alpha 0.0102 0.0112 0.0318
Echinococcus multilocularis dual specificity mitogen activated protein 0.0114 0.0141 0.0379
Loa Loa (eye worm) AUR protein kinase 0.0518 0.1071 0.1071
Loa Loa (eye worm) CAMK/PIM protein kinase 0.1248 0.2754 0.2754
Loa Loa (eye worm) TK/INSR protein kinase 0.0752 0.1611 0.1611
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0159 0.0243 0.2143
Entamoeba histolytica protein kinase, putative 0.0084 0.0071 0.0624
Loa Loa (eye worm) TK/FER protein kinase 0.0115 0.0142 0.0142
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0109 0.0129 0.0129
Echinococcus multilocularis tyrosine protein kinase Blk 0.0171 0.0273 0.0731
Echinococcus granulosus tyrosine protein kinase Srms 0.0115 0.0142 0.0404
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0159 0.0244 0.0655
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0275 0.0513 0.1375
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0157 0.0241 0.0241
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0087 0.0078 0.0687
Echinococcus multilocularis protein kinase shaggy 0.0545 0.1135 0.3043
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0095 0.0096 0.0096
Loa Loa (eye worm) STE/STE7/MEK1 protein kinase 0.0114 0.0141 0.0141
Schistosoma mansoni serine/threonine protein kinase 0.0058 0.0011 0.0032
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0159 0.0244 0.2152
Brugia malayi casein kinase I 0.0113 0.0138 0.0138
Loa Loa (eye worm) TK/FER protein kinase 0.0115 0.0142 0.0142
Echinococcus multilocularis tyrosine protein kinase HCK 0.0109 0.013 0.0349
Brugia malayi Immunoglobulin I-set domain containing protein 0.0072 0.0044 0.0044
Brugia malayi MAP kinase sur-1 0.0086 0.0076 0.0076
Schistosoma mansoni protein kinase 0.0171 0.0272 0.0771
Echinococcus multilocularis hemicentin 1 0.007 0.0038 0.0103
Brugia malayi serine/threonine-protein kinase PAK 7 0.1442 0.3202 0.3202
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0194 0.0326 0.0873
Brugia malayi hypothetical protein 0.0062 0.002 0.002
Schistosoma mansoni serine/threonine protein kinase 0.1248 0.2754 0.7808
Echinococcus multilocularis cyclin dependent kinase 1 0.0164 0.0257 0.0688
Trichomonas vaginalis CMGC family protein kinase 0.0164 0.0257 0.2262
Echinococcus multilocularis neural Wiskott Aldrich syndrome protein 0.0134 0.0187 0.05
Trichomonas vaginalis STE family protein kinase 0.0192 0.032 0.282
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.009 0.0085 0.0752
Echinococcus multilocularis cyclin dependent kinase 5 0.0164 0.0257 0.0688
Trichomonas vaginalis CAMK family protein kinase 0.0219 0.0383 0.3378
Brugia malayi Immunoglobulin I-set domain containing protein 0.007 0.0038 0.0038
Brugia malayi SH2 domain containing protein 0.0115 0.0142 0.0142
Schistosoma mansoni serine/threonine protein kinase 0.021 0.0362 0.1025
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0086 0.0076 0.0076
Echinococcus multilocularis mitogen activated protein kinase 3 0.0086 0.0076 0.0203
Brugia malayi RhoGAP domain containing protein 0.0095 0.0096 0.0096
Schistosoma mansoni tyrosine kinase 0.0187 0.0309 0.0875
Echinococcus granulosus tyrosine protein kinase Src42A 0.0194 0.0326 0.0923
Echinococcus multilocularis cyclin dependent kinase 9 0.0084 0.0072 0.0192
Giardia lamblia Kinase, STE STE20 0.0087 0.0078 0.0687
Loa Loa (eye worm) hypothetical protein 0.0138 0.0196 0.0196
Toxoplasma gondii histone kinase SNF1, putative 0.0082 0.0068 0.0595
Onchocerca volvulus 0.0115 0.0142 0.0436
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0072 0.0044 0.0117
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0103 0.0116 0.1019
Onchocerca volvulus 0.0092 0.0089 0.0273
Echinococcus granulosus MAP kinase activated protein kinase 2 0.0385 0.0765 0.2168
Schistosoma mansoni hypothetical protein 0.0062 0.002 0.0057
Brugia malayi cyclin-dependent kinase 7 homolog 0.0125 0.0167 0.0167
Plasmodium falciparum glycogen synthase kinase 3 0.0545 0.1135 1
Loa Loa (eye worm) TK protein kinase 0.0171 0.0273 0.0273
Echinococcus multilocularis SH2 domain containing protein 7 0.0062 0.002 0.0054
Echinococcus granulosus cyclin dependent kinase 9 0.0084 0.0072 0.0203
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0164 0.0257 0.2262
Loa Loa (eye worm) hypothetical protein 0.0062 0.002 0.002
Brugia malayi C1-like domain containing protein 0.0149 0.022 0.022
Toxoplasma gondii AGC kinase 0.0183 0.0299 0.263
Leishmania major protein kinase A catalytic subunit isoform 1 0.0159 0.0244 0.2152
Plasmodium falciparum NIMA related kinase 1 0.0136 0.0192 0.1693
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.007 0.0038 0.0038
Brugia malayi Dual specificity mitogen-activated protein kinase kinase mek-2 0.0114 0.0141 0.0141
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0163 0.0253 0.0253
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0163 0.0253 0.2228
Trichomonas vaginalis STE family protein kinase 0.0136 0.0192 0.1693
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0106 0.0121 0.0343
Echinococcus granulosus epidermal growth factor receptor 0.0924 0.2007 0.5691
Trypanosoma brucei SNF1-related protein kinases, putative 0.0082 0.0068 0.0595
Echinococcus granulosus tyrosine protein kinase HCK 0.0109 0.013 0.0369
Entamoeba histolytica casein kinase 1, putative 0.0113 0.0138 0.1216
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0086 0.0076 0.0669
Onchocerca volvulus Basement membrane proteoglycan homolog 0.007 0.0038 0.0118
Trichomonas vaginalis CK1 family protein kinase 0.0113 0.0138 0.1216
Brugia malayi WH1 domain containing protein 0.0134 0.0187 0.0187
Trichomonas vaginalis AGC family protein kinase 0.0116 0.0146 0.1287
Loa Loa (eye worm) SH2 domain-containing protein 0.0062 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0062 0.002 0.002
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0099 0.0106 0.0931
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0159 0.0244 0.0692
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0171 0.0272 0.0272
Trypanosoma brucei casein kinase I, isoform 2 0.0113 0.0138 0.1216
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0192 0.032 0.0907
Trichomonas vaginalis CMGC family protein kinase 0.0102 0.0112 0.0989
Loa Loa (eye worm) hypothetical protein 0.007 0.0038 0.0038
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0108 0.0128 0.1127
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0086 0.0076 0.0669
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0501 0.1032 0.1032
Trichomonas vaginalis CAMK family protein kinase 0.0082 0.0068 0.0595
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0754 0.1616 0.4582
Brugia malayi Protein kinase domain containing protein 0.0199 0.0336 0.0336
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0116 0.0146 0.0414
Echinococcus granulosus tensin C1 domain containing phosphatase 0.0062 0.002 0.0057
Echinococcus multilocularis ephrin type A receptor 4 A 0.0115 0.0142 0.0381
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0194 0.0326 0.0873
Brugia malayi Protein kinase domain containing protein 0.0309 0.059 0.059
Trichomonas vaginalis CAMK family protein kinase 0.0082 0.0068 0.0595
Echinococcus multilocularis 0.0126 0.0168 0.0449
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0082 0.0068 0.0181
Trichomonas vaginalis CMGC family protein kinase 0.0163 0.0253 0.2228
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0119 0.0152 0.1338
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0066 0.003 0.0081
Schistosoma mansoni serine/threonine kinase 0.0075 0.005 0.0142
Entamoeba histolytica protein kinase domain containing protein 0.0309 0.059 0.5198
Trichomonas vaginalis CMGC family protein kinase 0.0102 0.0112 0.0989
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0079 0.0061 0.0535
Loa Loa (eye worm) STAT protein 0.0062 0.002 0.002
Echinococcus granulosus N chimaerin 0.0095 0.0096 0.0273
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.1308 0.2893 0.8202
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0113 0.0138 0.1216
Echinococcus multilocularis roundabout 2 0.0072 0.0044 0.0117
Giardia lamblia Kinase, CMGC CLK 0.0163 0.0253 0.2228
Echinococcus granulosus serine:threonine protein kinase 3 0.0253 0.046 0.1304
Brugia malayi Immunoglobulin I-set domain containing protein 0.007 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.0119 0.0152 0.0152
Giardia lamblia Kinase, CMGC CK2 0.0102 0.0112 0.0989
Trichomonas vaginalis CAMK family protein kinase 0.0219 0.0383 0.3378
Giardia lamblia Kinase, NEK 0.0136 0.0192 0.1693
Schistosoma mansoni vav2 0.01 0.0108 0.0307
Entamoeba histolytica protein kinase, putative 0.0188 0.0311 0.2738
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0115 0.0142 0.0382
Echinococcus multilocularis death associated protein kinase 1 0.1671 0.373 1
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0164 0.0257 0.2262
Echinococcus granulosus NDR protein kinase 0.0116 0.0146 0.0414
Onchocerca volvulus 0.0062 0.002 0.0062
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0113 0.0138 0.0138
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0171 0.0273 0.0773
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0085 0.0074 0.0197
Entamoeba histolytica hypothetical protein 0.0053 0.0001 0.0006
Brugia malayi Tensin 0.0062 0.002 0.002
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0159 0.0243 0.2143
Echinococcus granulosus dual specificity mitogen activated protein 0.0114 0.0141 0.0401
Brugia malayi p70 ribosomal S6 kinase beta 0.0183 0.0299 0.0299
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0091 0.0086 0.0762
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0095 0.0096 0.0273
Giardia lamblia Kinase, AGC AKT 0.0118 0.015 0.132
Echinococcus multilocularis calcium:calmodulin dependent protein kinase I 0.0073 0.0047 0.0127
Brugia malayi map kinase activated protein kinase protein 2 0.0385 0.0765 0.0765
Brugia malayi SH2 domain containing protein 0.0062 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0135 0.0188 0.0188
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0194 0.0326 0.0873
Echinococcus multilocularis tyrosine protein kinase Srms 0.0171 0.0273 0.0731
Echinococcus granulosus suppressor of cytokine signaling 7 0.0062 0.002 0.0057
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0402 0.0804 0.2155
Echinococcus granulosus growth factor receptor bound protein 2 0.0085 0.0073 0.0208
Trichomonas vaginalis CAMK family protein kinase 0.0219 0.0383 0.3378
Schistosoma mansoni serine/threonine protein kinase 0.0066 0.0031 0.0088
Echinococcus granulosus neuroglian 0.0167 0.0262 0.0742
Brugia malayi Protein kinase domain containing protein 0.1248 0.2754 0.2754
Entamoeba histolytica protein kinase, putative 0.0074 0.0047 0.0417
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0163 0.0253 0.2228
Giardia lamblia Kinase, CMGC MAPK 0.0086 0.0076 0.0669
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.0253 0.046 0.046
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0157 0.0241 0.0241
Echinococcus granulosus expressed conserved protein 0.0112 0.0135 0.0383
Echinococcus multilocularis cyclin dependent kinase 1 0.0164 0.0257 0.0688
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0103 0.0116 0.0328
Schistosoma mansoni tyrosine kinase 0.1583 0.3527 1
Echinococcus multilocularis expressed conserved protein 0.0112 0.0135 0.0363
Loa Loa (eye worm) hypothetical protein 0.0062 0.002 0.002
Echinococcus multilocularis tensin 0.0062 0.002 0.0054
Trichomonas vaginalis CAMK family protein kinase 0.0082 0.0068 0.0595
Echinococcus granulosus Protein kinase C brain isozyme 0.0189 0.0313 0.0887
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0159 0.0244 0.0692
Entamoeba histolytica protein kinase, putative 0.0176 0.0284 0.2503
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0159 0.0243 0.0243
Loa Loa (eye worm) hypothetical protein 0.0134 0.0186 0.0186
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0545 0.1135 1
Schistosoma mansoni SH2A 0.0062 0.002 0.0057
Echinococcus granulosus titin 0.0071 0.0042 0.0119
Echinococcus granulosus cyclin dependent kinase 9 0.0092 0.0091 0.0257
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.009 0.0085 0.0752
Trichomonas vaginalis AGC family protein kinase 0.0188 0.0311 0.2738
Schistosoma mansoni serine/threonine protein kinase 0.0151 0.0225 0.0637
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0163 0.0253 0.2228
Echinococcus granulosus cyclin dependent kinase 0.0164 0.0257 0.0728
Echinococcus multilocularis twitchin 0.0069 0.0037 0.0099
Echinococcus granulosus tyrosine kinase 0.0115 0.0142 0.0404
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0085 0.0073 0.0208
Echinococcus multilocularis hemicentin 1 0.007 0.0038 0.0103
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0086 0.0076 0.0669
Plasmodium falciparum casein kinase 1 0.0113 0.0138 0.1216
Schistosoma mansoni ste20-related kinase 0.0203 0.0345 0.0979
Entamoeba histolytica serine/threonine protein kinase, putative 0.0219 0.0383 0.3378
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0163 0.0253 0.2228
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0219 0.0383 0.1028
Echinococcus multilocularis activin receptor type 0.009 0.0085 0.0229
Brugia malayi Protein kinase c protein 2 0.0109 0.013 0.013
Loa Loa (eye worm) hypothetical protein 0.0272 0.0505 0.0505
Trichomonas vaginalis CMGC family protein kinase 0.0545 0.1135 1
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0159 0.0244 0.0655
Loa Loa (eye worm) TK/ABL protein kinase 0.0314 0.0603 0.0603
Brugia malayi Protein kinase domain containing protein 0.0076 0.0053 0.0053
Trypanosoma cruzi cdc2-related kinase 3 0.0164 0.0257 0.2262
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0103 0.0116 0.1019
Loa Loa (eye worm) hypothetical protein 0.0112 0.0135 0.0135
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0192 0.032 0.0858
Echinococcus granulosus epidermal growth factor receptor 0.1583 0.3527 1
Schistosoma mansoni serine/threonine protein kinase 0.0082 0.0068 0.0191
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0287 0.054 0.054
Echinococcus multilocularis roundabout 2 0.0072 0.0044 0.0117
Leishmania major protein kinase, putative 0.0518 0.1071 0.9434
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0086 0.0076 0.0669
Schistosoma mansoni tyrosine kinase 0.0924 0.2007 0.5691
Schistosoma mansoni serine/threonine protein kinase 0.0082 0.0068 0.0191
Plasmodium falciparum serine/threonine protein kinase, putative 0.0518 0.1071 0.9434
Entamoeba histolytica hypothetical protein 0.0134 0.0187 0.1644
Onchocerca volvulus 0.0079 0.0059 0.018
Echinococcus multilocularis rac serine:threonine kinase 0.0108 0.0128 0.0343
Schistosoma mansoni protein kinase C mu 0.0149 0.022 0.0624
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.0082 0.0068 0.0595
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0545 0.1135 1
Trichomonas vaginalis CAMK family protein kinase 0.0076 0.0053 0.0469
Schistosoma mansoni serine/threonine protein kinase 0.0106 0.0121 0.0343
Onchocerca volvulus 0.0113 0.0138 0.0423
Schistosoma mansoni serine/threonine protein kinase 0.0086 0.0076 0.0215
Loa Loa (eye worm) TK protein kinase 0.0109 0.013 0.013
Trichomonas vaginalis AGC family protein kinase 0.0122 0.0158 0.1395
Schistosoma mansoni serine/threonine protein kinase 0.0127 0.0171 0.0484
Brugia malayi SH2 domain containing protein 0.0062 0.002 0.002
Loa Loa (eye worm) AGC/AKT protein kinase 0.0188 0.0311 0.0311
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0062 0.002 0.0057
Echinococcus granulosus tyrosine protein kinase Lyn 0.0231 0.0411 0.1165
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.0066 0.0031 0.0031
Echinococcus granulosus serine:threonine protein kinase 0.0076 0.0053 0.0151
Echinococcus granulosus calcium:calmodulin dependent protein kinase I 0.0073 0.0047 0.0134
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0084 0.0071 0.019
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.1248 0.2754 0.7384
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.009 0.0085 0.0752
Trichomonas vaginalis CAMK family protein kinase 0.0127 0.0171 0.1502
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0062 0.002 0.0054
Trypanosoma brucei rac serine-threonine kinase, putative 0.0188 0.0311 0.2738
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0149 0.022 0.022
Echinococcus multilocularis SHC transforming protein 3 0.0062 0.002 0.0054
Loa Loa (eye worm) hypothetical protein 0.007 0.0038 0.0038
Entamoeba histolytica protein kinase, putative 0.0183 0.0299 0.263
Loa Loa (eye worm) CMGC/CDK/CDK9 protein kinase 0.0084 0.0072 0.0072
Echinococcus multilocularis Immunoglobulin 0.0135 0.0188 0.0505
Loa Loa (eye worm) hypothetical protein 0.0126 0.0168 0.0168
Schistosoma mansoni serine/threonine protein kinase 0.0171 0.0272 0.077
Schistosoma mansoni tyrosine kinase 0.0871 0.1885 0.5345
Onchocerca volvulus 0.0115 0.0142 0.0436
Brugia malayi Protein kinase domain containing protein 0.0115 0.0142 0.0142
Plasmodium falciparum serine/threonine protein kinase KIN 0.0082 0.0068 0.0595
Schistosoma mansoni atypical protein kinase C 0.0235 0.0419 0.1189
Echinococcus multilocularis PAK box P21 Rho binding 0.0134 0.0187 0.05
Loa Loa (eye worm) CMGC/CDK/CDK7 protein kinase 0.0117 0.0148 0.0148
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0164 0.0257 0.0257
Echinococcus multilocularis serine:threonine protein kinase Chk2 0.0074 0.0047 0.0127
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0275 0.0513 0.0513
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0183 0.0299 0.0299
Loa Loa (eye worm) hypothetical protein 0.0062 0.002 0.002
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0164 0.0257 0.0257
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0194 0.0326 0.0873
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0309 0.059 0.5198
Echinococcus multilocularis rho associated protein kinase 0.1437 0.3189 0.8551
Entamoeba histolytica protein kinase domain containing protein 0.0084 0.0072 0.063
Schistosoma mansoni hypothetical protein 0.0134 0.0187 0.0529
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.1248 0.2754 0.7808
Schistosoma mansoni suppressor of cytokine signaling 0.0062 0.002 0.0057
Echinococcus multilocularis mitogen activated protein kinase 14 0.0159 0.0243 0.0652
Echinococcus granulosus casein kinase i 0.0113 0.0138 0.0391
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0087 0.0078 0.0687
Trichomonas vaginalis CMGC family protein kinase 0.0102 0.0112 0.0989
Echinococcus granulosus Glutaredoxin protein 5 0.0066 0.003 0.0086
Brugia malayi ephrin receptor 1 precursor 0.0082 0.0067 0.0067
Echinococcus granulosus c src tyrosine kinase 0.0138 0.0195 0.0554
Echinococcus granulosus tyrosine protein kinase Fyn 0.0194 0.0326 0.0923
Schistosoma mansoni serine/threonine protein kinase 0.0069 0.0037 0.0104
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0086 0.0076 0.0669
Loa Loa (eye worm) TK/FER protein kinase 0.0115 0.0142 0.0142
Schistosoma mansoni nephrin 0.0072 0.0044 0.0124
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0518 0.1071 0.9434
Schistosoma mansoni protein kinase 0.009 0.0085 0.0242
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0149 0.022 0.022
Giardia lamblia Kinase, AGC PKA 0.0159 0.0244 0.2152
Schistosoma mansoni cell adhesion molecule 0.0072 0.0044 0.0124
Echinococcus multilocularis leucine rich repeat serine:threonine protein 0.0098 0.0104 0.0278
Echinococcus multilocularis protein kinase c epsilon type 0.0151 0.0225 0.0603
Echinococcus multilocularis serine threonine protein kinase 0.0156 0.0237 0.0635
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0164 0.0257 0.2262
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0219 0.0383 0.0383
Entamoeba histolytica hypothetical protein 0.0053 0.0001 0.0006
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0159 0.0244 0.0655
Echinococcus granulosus tensin 0.0062 0.002 0.0057
Schistosoma mansoni nck2/grb4 0.0085 0.0073 0.0208
Echinococcus granulosus aurora kinase A 0.0518 0.1071 0.3035
Schistosoma mansoni serine/threonine protein kinase 0.1437 0.3189 0.9042
Onchocerca volvulus 0.0062 0.002 0.0062
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.0082 0.0068 0.0595
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0314 0.0603 0.1616
Echinococcus multilocularis mitogen activated protein kinase 0.0086 0.0076 0.0203
Echinococcus granulosus SHC transforming protein 3 0.0062 0.002 0.0057
Schistosoma mansoni tyrosine-protein kinase zap-70 0.0062 0.002 0.0057
Echinococcus multilocularis calcium activated potassium channel 0.0066 0.0031 0.0083
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0197 0.0333 0.0333
Brugia malayi Protein kinase domain containing protein 0.0115 0.0142 0.0142
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.0058 0.0011 0.0011
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0062 0.002 0.0054
Brugia malayi Protein kinase domain containing protein 0.0116 0.0146 0.0146
Loa Loa (eye worm) hypothetical protein 0.0076 0.0053 0.0053
Schistosoma mansoni tyrosine kinase 0.0752 0.1611 0.4567
Schistosoma mansoni serine/threonine protein kinase 0.0275 0.0513 0.1454
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0163 0.0253 0.2228
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0159 0.0244 0.0655
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0402 0.0804 0.2279
Brugia malayi hypothetical protein 0.0137 0.0194 0.0194
Loa Loa (eye worm) hypothetical protein 0.0137 0.0194 0.0194
Trypanosoma cruzi aurora B kinase, putative 0.0518 0.1071 0.9434
Schistosoma mansoni tyrosine kinase 0.0194 0.0326 0.0923
Brugia malayi SRC-1 0.0194 0.0326 0.0326
Plasmodium vivax serine/threonine kinase-1, putative 0.0163 0.0253 0.2228
Schistosoma mansoni tensin 0.0062 0.002 0.0057
Echinococcus multilocularis serine:threonine protein kinase 38 0.0116 0.0146 0.0392
Echinococcus granulosus c-Jun N-terminal kinases 0.0501 0.1032 0.2925
Brugia malayi protein kinase C3,putative 0.015 0.0223 0.0223
Echinococcus multilocularis serine:threonine protein kinase N2 0.0116 0.0146 0.0392
Brugia malayi Protein kinase domain containing protein 0.0185 0.0303 0.0303
Echinococcus granulosus SH2 motif 0.0062 0.002 0.0057
Loa Loa (eye worm) hypothetical protein 0.007 0.0039 0.0039
Onchocerca volvulus 0.0062 0.002 0.0062
Schistosoma mansoni tensin 0.0062 0.002 0.0057
Plasmodium vivax protein kinase, putative 0.0058 0.0011 0.0098
Loa Loa (eye worm) hypothetical protein 0.0167 0.0262 0.0262
Echinococcus multilocularis tyrosine protein kinase Abl 0.0214 0.0371 0.0996
Entamoeba histolytica serine/threonine-protein kinase 3, putative 0.0087 0.0078 0.0687
Schistosoma mansoni tyrosine kinase 0.0194 0.0326 0.0923
Brugia malayi protein kinase C II. 0.0151 0.0225 0.0225
Schistosoma mansoni hypothetical protein 0.0062 0.002 0.0057
Loa Loa (eye worm) SH2 domain-containing protein 0.0062 0.002 0.002
Schistosoma mansoni serine/threonine protein kinase 0.0163 0.0253 0.0717
Brugia malayi ribosomal protein S6 kinase alpha 3 0.0118 0.015 0.015
Schistosoma mansoni tensin 0.0062 0.002 0.0057
Trichomonas vaginalis STE family protein kinase 0.0087 0.0078 0.0687
Loa Loa (eye worm) hypothetical protein 0.0062 0.002 0.002
Brugia malayi p21/Cdc42/Rac1-activated kinase 0.0058 0.0011 0.0011
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0194 0.0326 0.0873
Trichomonas vaginalis STE family protein kinase 0.0171 0.0272 0.2396
Echinococcus granulosus tyrosine protein kinase Fyn 0.0194 0.0326 0.0923
Echinococcus granulosus phosphatidylinositol 3 kinase regulatory subunit 0.0062 0.002 0.0057
Trichomonas vaginalis AGC family protein kinase 0.0518 0.1071 0.9434
Trichomonas vaginalis CK1 family protein kinase 0.0113 0.0138 0.1216
Plasmodium vivax glycogen synthase kinase 3, putative 0.0545 0.1135 1
Trichomonas vaginalis AGC family protein kinase 0.0188 0.0311 0.2738
Brugia malayi SH2 domain containing protein 0.0115 0.0142 0.0142
Brugia malayi SH2 domain containing protein 0.0062 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0062 0.002 0.002
Trichomonas vaginalis CMGC family protein kinase 0.0102 0.0112 0.0989
Echinococcus multilocularis neuroglian 0.0072 0.0044 0.0117
Schistosoma mansoni signal transduction protein lnk-related 0.0062 0.002 0.0057
Brugia malayi Tyrosine-protein kinase abl-1 0.0214 0.0371 0.0371
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0979 0.2135 0.5724
Echinococcus granulosus cyclin dependent kinase 5 0.0164 0.0257 0.0728
Echinococcus multilocularis SH2 motif 0.0062 0.002 0.0054
Schistosoma mansoni kinase 0.0129 0.0176 0.0499
Echinococcus granulosus SH2 domain containing protein 7 0.0062 0.002 0.0057
Loa Loa (eye worm) hypothetical protein 0.0085 0.0073 0.0073
Toxoplasma gondii AGC kinase 0.0159 0.0244 0.2152
Schistosoma mansoni protein kinase 0.0192 0.032 0.0907
Loa Loa (eye worm) hypothetical protein 0.0079 0.0059 0.0059
Brugia malayi Protein kinase domain containing protein 0.0191 0.0319 0.0319
Schistosoma mansoni serine/threonine protein kinase 0.0501 0.1032 0.2925
Echinococcus granulosus protein kinase shaggy 0.0545 0.1135 0.3218
Entamoeba histolytica protein kinase , putative 0.0518 0.1071 0.9434
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0194 0.0326 0.0923
Giardia lamblia Kinase, CMGC CDK 0.0164 0.0257 0.2262
Loa Loa (eye worm) gastrulation defective protein 1 0.0137 0.0193 0.0193
Echinococcus granulosus lachesin 0.007 0.0038 0.0109
Echinococcus multilocularis casein kinase I alpha 0.0113 0.0138 0.037
Onchocerca volvulus 0.0062 0.002 0.0062
Echinococcus granulosus nervana 2 0.0066 0.003 0.0086
Brugia malayi Hr1 repeat family protein 0.0116 0.0146 0.0146
Echinococcus multilocularis mitogen activated protein kinase 11 0.0159 0.0243 0.0652
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0121 0.0156 0.0443
Brugia malayi Fibronectin type III domain containing protein 0.0137 0.0194 0.0194
Brugia malayi STE20-like kinase MST 0.0253 0.046 0.046
Echinococcus multilocularis casein kinase ii subunit alpha 0.0102 0.0112 0.0301
Onchocerca volvulus Serine\/threonine kinase homolog 0.0219 0.0383 0.1173
Entamoeba histolytica hypothetical protein 0.0053 0.0001 0.0006
Trichomonas vaginalis CAMK family protein kinase 0.0082 0.0068 0.0595
Echinococcus granulosus serine:threonine protein kinase 0.0076 0.0053 0.0151
Loa Loa (eye worm) CAMK protein kinase 0.0071 0.0042 0.0042
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0072 0.0044 0.0124
Echinococcus multilocularis G protein coupled receptor kinase 6 0.0157 0.0241 0.0646
Echinococcus granulosus neuroglian 0.0072 0.0044 0.0124
Entamoeba histolytica protein kinase, putative 0.0518 0.1071 0.9434
Schistosoma mansoni serine/threonine protein kinase 0.0113 0.0138 0.0391
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0518 0.1071 0.9434
Loa Loa (eye worm) hypothetical protein 0.0071 0.0042 0.0042
Trichomonas vaginalis CAMK family protein kinase 0.0082 0.0068 0.0595
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0138 0.0195 0.0554
Loa Loa (eye worm) hypothetical protein 0.0135 0.0189 0.0189
Echinococcus multilocularis epidermal growth factor receptor 0.1583 0.3527 0.9456
Loa Loa (eye worm) AGC/NDR protein kinase 0.0116 0.0146 0.0146
Echinococcus granulosus suppressor of cytokine signaling 6 0.0062 0.002 0.0057
Echinococcus multilocularis neuroglian 0.0167 0.0262 0.0702
Echinococcus multilocularis epidermal growth factor receptor 0.0924 0.2007 0.5382
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0194 0.0326 0.0873
Giardia lamblia Kinase, CMGC GSK 0.0545 0.1135 1
Giardia lamblia Kinase, PLK 0.0219 0.0383 0.3378
Loa Loa (eye worm) AUR protein kinase 0.0518 0.1071 0.1071
Trypanosoma brucei protein kinase, putative 0.0545 0.1135 1
Entamoeba histolytica protein kinase domain containing protein 0.0518 0.1071 0.9434
Schistosoma mansoni tyrosine kinase 0.0243 0.0438 0.1243
Brugia malayi Variant SH3 domain containing protein 0.0068 0.0035 0.0035
Brugia malayi Immunoglobulin I-set domain containing protein 0.0071 0.0042 0.0042
Schistosoma mansoni septate junction protein 0.007 0.0038 0.0109
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0194 0.0326 0.0873
Trichomonas vaginalis CMGC family protein kinase 0.0545 0.1135 1
Entamoeba histolytica protein kinase, putative 0.0116 0.0146 0.1287
Brugia malayi Protein kinase domain containing protein 0.0188 0.0311 0.0311
Brugia malayi Protein kinase domain containing protein 0.0164 0.0257 0.0257
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0106 0.0121 0.0325
Plasmodium falciparum protein serine/threonine kinase-1 0.0163 0.0253 0.2228
Trypanosoma brucei aurora B kinase 0.0518 0.1071 0.9434
Echinococcus multilocularis casein kinase i 0.0113 0.0138 0.037
Schistosoma mansoni growth factor receptor-bound protein 0.0085 0.0073 0.0208
Brugia malayi Immunoglobulin I-set domain containing protein 0.0276 0.0513 0.0513
Echinococcus granulosus serine:threonine protein kinase N2 0.0116 0.0146 0.0414
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0095 0.0096 0.0258
Schistosoma mansoni growth factor receptor-bound protein 0.0085 0.0073 0.0208
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0116 0.0146 0.0392
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0518 0.1071 0.9434
Entamoeba histolytica protein kinase 2, putative 0.0103 0.0116 0.1019
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0159 0.0244 0.2152
Trichomonas vaginalis STE family protein kinase 0.0114 0.0141 0.1245
Trypanosoma brucei mitogen-activated protein kinase kinase 5 0.0114 0.0141 0.1245
Echinococcus multilocularis 0.0474 0.0971 0.2603
Echinococcus multilocularis suppressor of cytokine signaling 6 0.0062 0.002 0.0054
Onchocerca volvulus 0.0062 0.002 0.0062
Echinococcus granulosus PAK box P21 Rho binding 0.0134 0.0187 0.0529
Schistosoma mansoni hypothetical protein 0.0134 0.0187 0.0529
Echinococcus granulosus nervana 2 0.0066 0.003 0.0086
Loa Loa (eye worm) cytokine inducible SH2-containing protein 5 0.0062 0.002 0.002
Giardia lamblia Kinase, NEK 0.0136 0.0192 0.1693
Loa Loa (eye worm) hypothetical protein 0.0204 0.0349 0.0349
Brugia malayi tRNA modification GTPase TrmE family protein 0.0062 0.002 0.002
Loa Loa (eye worm) SRC-1 0.0194 0.0326 0.0326
Echinococcus granulosus cyclin dependent kinase 1 0.0164 0.0257 0.0728
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0102 0.0112 0.0989
Trypanosoma cruzi polo-like protein kinase, putative 0.0219 0.0383 0.3378
Loa Loa (eye worm) hypothetical protein 0.0062 0.002 0.002
Echinococcus granulosus serine threonine protein kinase nrc 0.0103 0.0116 0.0328
Onchocerca volvulus 0.0115 0.0142 0.0436
Trichomonas vaginalis AGC family protein kinase 0.0084 0.0071 0.0624
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0518 0.1071 0.3035
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0171 0.0273 0.0731
Echinococcus multilocularis tensin 0.0062 0.002 0.0054
Loa Loa (eye worm) TK protein kinase 0.0276 0.0513 0.0513
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0115 0.0142 0.1255
Entamoeba histolytica protein kinase domain containing protein 0.0545 0.1135 1
Onchocerca volvulus 0.0115 0.0142 0.0436
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0116 0.0146 0.0392
Brugia malayi Serine/threonine-protein kinase Pim-3 0.1248 0.2754 0.2754
Trichomonas vaginalis AGC family protein kinase 0.0188 0.0311 0.2738
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0192 0.032 0.0858
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0113 0.0138 0.0138
Echinococcus granulosus SH2 domain containing adapter protein F 0.0062 0.002 0.0057
Entamoeba histolytica PH domain containing protein kinase, putative 0.0108 0.0128 0.1127
Trichomonas vaginalis CAMK family protein kinase 0.0219 0.0383 0.3378
Brugia malayi cytokine inducible SH2-containing protein 5 0.0062 0.002 0.002
Echinococcus multilocularis growth factor receptor bound protein 2 0.0085 0.0073 0.0196
Trichomonas vaginalis AGC family protein kinase 0.0125 0.0165 0.1454
Echinococcus granulosus tyrosine protein kinase shark 0.0115 0.0142 0.0404
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0066 0.003 0.0086
Brugia malayi phosphoinositide-dependent protein kinase I 0.0084 0.0071 0.0071
Onchocerca volvulus 0.0071 0.0042 0.0129
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0159 0.0244 0.2152
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0095 0.0096 0.0273
Brugia malayi Immunoglobulin I-set domain containing protein 0.0072 0.0044 0.0044
Trichomonas vaginalis CAMK family protein kinase 0.0219 0.0383 0.3378
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0192 0.032 0.0858
Onchocerca volvulus 0.1386 0.3071 0.9401
Loa Loa (eye worm) TK/FER protein kinase 0.0115 0.0142 0.0142
Schistosoma mansoni protein kinase 0.0113 0.0138 0.0391
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0103 0.0116 0.1019
Entamoeba histolytica p21-activated kinase 0.0197 0.0332 0.2927
Loa Loa (eye worm) hypothetical protein 0.0062 0.002 0.002
Giardia lamblia Kinase, CK1 Casein kinase 0.0113 0.0138 0.1216
Onchocerca volvulus 0.0115 0.0142 0.0436
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0518 0.1071 0.287
Schistosoma mansoni serine/threonine protein kinase 0.0159 0.0244 0.0692
Trypanosoma cruzi mitogen-activated protein kinase kinase 5 0.0114 0.0141 0.1245
Echinococcus granulosus NCK adaptor protein 0.0085 0.0073 0.0208
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0159 0.0244 0.2152
Schistosoma mansoni hypothetical protein 0.0134 0.0187 0.0529
Brugia malayi cyclin-dependent kinase 9 0.0084 0.0072 0.0072
Brugia malayi Temporarily assigned gene name protein 59 0.0124 0.0164 0.0164
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0071 0.0042 0.0042
Trichomonas vaginalis AGC family protein kinase 0.0136 0.0192 0.1693
Schistosoma mansoni titin 0.0071 0.0042 0.0119
Echinococcus multilocularis N chimaerin 0.0095 0.0096 0.0258
Schistosoma mansoni serine/threonine protein kinase 0.0117 0.0148 0.042
Schistosoma mansoni tyrosine kinase 0.0123 0.0161 0.0455
Entamoeba histolytica PH domain containing protein kinase, putative 0.0164 0.0256 0.226
Trypanosoma cruzi casein kinase, putative 0.0113 0.0138 0.1216
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0163 0.0253 0.2228
Plasmodium vivax casein kinase 1, putative 0.0113 0.0138 0.1216
Loa Loa (eye worm) hypothetical protein 0.0117 0.0147 0.0147
Echinococcus granulosus leucine rich repeat serine:threonine protein 0.0098 0.0104 0.0296
Echinococcus granulosus Niemann Pick C1 protein 0.0119 0.0152 0.0431
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0219 0.0383 0.3378
Echinococcus multilocularis SH2 motif 0.0062 0.002 0.0054
Echinococcus granulosus casein kinase I alpha 0.0113 0.0138 0.0391
Echinococcus granulosus casein kinase I delta 0.0113 0.0138 0.0391
Entamoeba histolytica serine/threonine protein kinase STE20, putative 0.0087 0.0078 0.0687
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0122 0.0159 0.045
Schistosoma mansoni serine/threonine protein kinase 0.0084 0.0071 0.0201
Echinococcus granulosus twitchin 0.0204 0.0347 0.0984
Schistosoma mansoni serine/threonine protein kinase 0.0084 0.0072 0.0203
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0118 0.015 0.0403
Echinococcus granulosus ephrin type A receptor 4 A 0.0115 0.0142 0.0403
Echinococcus multilocularis insulin receptor 0.0752 0.1611 0.4318
Trichomonas vaginalis AGC family protein kinase 0.0518 0.1071 0.9434
Leishmania major protein kinase, putative 0.0163 0.0253 0.2228
Trichomonas vaginalis CMGC family protein kinase 0.0102 0.0112 0.0989
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0309 0.059 0.5198
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0244 0.044 0.1179
Trichomonas vaginalis CAMK family protein kinase 0.0082 0.0068 0.0595
Schistosoma mansoni kinase 0.0084 0.0072 0.0203
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0136 0.0192 0.1693
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0086 0.0076 0.0669
Schistosoma mansoni serine/threonine protein kinase 0.0074 0.0047 0.0134
Echinococcus multilocularis serine:threonine protein kinase 0.0076 0.0053 0.0143
Brugia malayi Immunoglobulin I-set domain containing protein 0.1611 0.3591 0.3591
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0076 0.0053 0.0464
Echinococcus multilocularis SH2 motif 0.0062 0.002 0.0054
Trichomonas vaginalis CAMK family protein kinase 0.0082 0.0068 0.0595
Echinococcus granulosus protein kinase C gamma type 0.0156 0.0237 0.0672
Schistosoma mansoni protein kinase 0.0402 0.0804 0.2279
Plasmodium vivax protein kinase Crk2 0.0164 0.0257 0.2262
Echinococcus multilocularis 0.0062 0.002 0.0054
Trichomonas vaginalis CMGC family protein kinase 0.0102 0.0112 0.0989
Schistosoma mansoni wiskott-aldrich syndrome protein 0.0134 0.0187 0.0529
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0062 0.002 0.0054
Entamoeba histolytica PH domain containing protein kinase, putative 0.0108 0.0128 0.1127
Brugia malayi Prion-like- 0.007 0.0038 0.0038
Trichomonas vaginalis CAMK family protein kinase 0.0082 0.0068 0.0595
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0266 0.0491 0.1393
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0199 0.0336 0.0336
Entamoeba histolytica protein kinase, putative 0.0109 0.013 0.1147
Trichomonas vaginalis STE family protein kinase 0.0192 0.032 0.282
Trichomonas vaginalis CAMK family protein kinase 0.0082 0.0068 0.0595
Echinococcus granulosus dual specificity protein kinase clk2 0.0163 0.0253 0.0717
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0159 0.0244 0.2152
Echinococcus granulosus roundabout 2 0.0072 0.0044 0.0124
Brugia malayi Immunoglobulin I-set domain containing protein 0.0137 0.0194 0.0194
Brugia malayi SH2 domain containing protein 0.0062 0.002 0.002
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.0385 0.0765 0.0765
Schistosoma mansoni tyrosine kinase 0.0752 0.1611 0.4567
Trypanosoma cruzi casein kinase, putative 0.0113 0.0138 0.1216
Trichomonas vaginalis AGC family protein kinase 0.0188 0.0311 0.2738
Entamoeba histolytica protein kinase, putative 0.0309 0.059 0.5198
Schistosoma mansoni protein kinase 0.0134 0.0187 0.0529
Giardia lamblia Aurora kinase 0.0518 0.1071 0.9434
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0159 0.0244 0.2152
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0082 0.0068 0.0595
Loa Loa (eye worm) hypothetical protein 0.0082 0.0068 0.0068
Trichomonas vaginalis CAMK family protein kinase 0.0127 0.0171 0.1502
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.0076 0.0053 0.0053
Entamoeba histolytica protein kinase domain containing protein 0.009 0.0085 0.0752
Echinococcus multilocularis dual specificity 0.0309 0.059 0.1582
Loa Loa (eye worm) TK/EPH protein kinase 0.0132 0.0181 0.0181
Echinococcus granulosus mitogen activated protein kinase 0.0086 0.0076 0.0215
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0275 0.0513 0.1454
Loa Loa (eye worm) hypothetical protein 0.0072 0.0044 0.0044
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0115 0.0142 0.0404
Entamoeba histolytica SH2 domain containing protein 0.0062 0.002 0.0179
Trypanosoma brucei polo-like protein kinase 0.0219 0.0383 0.3378
Echinococcus granulosus fibroblast growth factor receptor 4 0.0244 0.044 0.1247
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0197 0.0333 0.0892
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0172 0.0275 0.0781
Schistosoma mansoni tensin-related 0.0062 0.002 0.0057
Schistosoma mansoni vesicular amine transporter 0.0135 0.0188 0.0534
Echinococcus multilocularis Niemann Pick C1 protein 0.0119 0.0152 0.0407
Loa Loa (eye worm) AGC/PKA protein kinase 0.0159 0.0244 0.0244
Schistosoma mansoni tyrosine kinase 0.0138 0.0195 0.0554
Entamoeba histolytica cell division protein kinase 2, putative 0.0164 0.0257 0.2262
Loa Loa (eye worm) hypothetical protein 0.0172 0.0275 0.0275
Brugia malayi Protein kinase domain containing protein 0.0174 0.0278 0.0278
Echinococcus granulosus SH2 motif 0.0062 0.002 0.0057
Echinococcus multilocularis protein dispatched 1 0.0058 0.0012 0.0032
Loa Loa (eye worm) hypothetical protein 0.0134 0.0186 0.0186
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0159 0.0244 0.0692
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0102 0.0112 0.0112
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0082 0.0068 0.0595
Trypanosoma brucei STE20-like serine/threonine-protein kinase 1, putative 0.0087 0.0078 0.0687
Echinococcus granulosus expressed conserved protein 0.0062 0.002 0.0057
Brugia malayi Peroxidasin 0.007 0.0039 0.0039
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0072 0.0044 0.0117
Brugia malayi Casein kinase II, alpha chain 0.0102 0.0112 0.0112
Trichomonas vaginalis CAMK family protein kinase 0.0066 0.0031 0.0273
Echinococcus multilocularis casein kinase I alpha 0.0113 0.0138 0.037
Schistosoma mansoni tyrosine kinase 0.0115 0.0142 0.0404
Echinococcus multilocularis titin 0.0071 0.0042 0.0113
Echinococcus granulosus tyrosine protein kinase otk 0.007 0.0038 0.0109
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0244 0.044 0.1179
Trichomonas vaginalis CAMK family protein kinase 0.0082 0.0068 0.0595
Brugia malayi P21-Rho-binding domain containing protein 0.0134 0.0187 0.0187
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0058 0.0011 0.01
Schistosoma mansoni serine/threonine protein kinase 0.0116 0.0146 0.0414
Trichomonas vaginalis AGC family protein kinase 0.0116 0.0146 0.1287
Brugia malayi Protein kinase domain containing protein 0.0066 0.0031 0.0031
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.009 0.0085 0.0752
Loa Loa (eye worm) hypothetical protein 0.0062 0.002 0.002
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0076 0.0054 0.0054
Schistosoma mansoni protein kinase 0.0402 0.0804 0.2279
Echinococcus granulosus rho-associated protein kinase 1 0.1437 0.3189 0.9042
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0924 0.2007 0.5691
Brugia malayi Tyrosine-protein kinase abl-1 0.0123 0.0162 0.0162
Trichomonas vaginalis CMGC family protein kinase 0.0092 0.0089 0.0786
Loa Loa (eye worm) hypothetical protein 0.0289 0.0544 0.0544
Echinococcus granulosus dual specificity 0.0309 0.059 0.1673
Loa Loa (eye worm) hypothetical protein 0.0137 0.0194 0.0194
Brugia malayi Protein kinase domain 0.0192 0.032 0.032
Loa Loa (eye worm) CDC7 protein kinase 0.0092 0.0089 0.0089
Entamoeba histolytica cell division protein kinase 2, putative 0.0173 0.0276 0.2429
Echinococcus granulosus signal transduction protein lnk realted 0.0062 0.002 0.0057
Entamoeba histolytica protein kinase, putative 0.0192 0.032 0.282
Schistosoma mansoni GTPase activating protein 0.0062 0.002 0.0057
Trichomonas vaginalis CAMK family protein kinase 0.0228 0.0402 0.3545
Trichomonas vaginalis AGC family protein kinase 0.0518 0.1071 0.9434
Brugia malayi serine/threonine protein kinase 6 0.0518 0.1071 0.1071
Echinococcus granulosus insulin receptor 0.0752 0.1611 0.4567
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0095 0.0096 0.0273
Echinococcus multilocularis aurora kinase A 0.0518 0.1071 0.287
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0545 0.1135 0.1135
Plasmodium falciparum protein kinase, putative 0.009 0.0085 0.0752
Onchocerca volvulus 0.0062 0.002 0.0062
Echinococcus granulosus cyclin dependent kinase 19 0.0174 0.0278 0.0788
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0072 0.0044 0.0124
Brugia malayi cell division control protein 2 homolog 0.0164 0.0257 0.0257
Onchocerca volvulus 0.0545 0.1135 0.3474
Leishmania major protein kinase A catalytic subunit 0.0159 0.0244 0.2152
Entamoeba histolytica protein kinase, putative 0.0171 0.0272 0.2396
Schistosoma mansoni tensin-related 0.0062 0.002 0.0057
Loa Loa (eye worm) TK/ROR protein kinase 0.0085 0.0074 0.0074
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0159 0.0244 0.2152
Brugia malayi protein-tyrosine kinase 0.0171 0.0273 0.0273
Loa Loa (eye worm) TK/FER protein kinase 0.0115 0.0142 0.0142
Schistosoma mansoni protein kinase 0.0114 0.0141 0.0401
Schistosoma mansoni serine/threonine protein kinase 0.0082 0.0068 0.0191
Loa Loa (eye worm) hypothetical protein 0.0155 0.0235 0.0235
Echinococcus multilocularis lachesin 0.007 0.0038 0.0103
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0192 0.032 0.0907
Echinococcus multilocularis nervana 2 0.0066 0.003 0.0081
Trichomonas vaginalis CAMK family protein kinase 0.0082 0.0068 0.0595
Onchocerca volvulus 0.0064 0.0026 0.0078
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.1248 0.2754 0.843
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0116 0.0146 0.0414
Giardia lamblia Kinase, CDC7 0.0092 0.0089 0.0786
Trichomonas vaginalis CK1 family protein kinase 0.0113 0.0138 0.1216
Leishmania major casein kinase II, putative 0.0102 0.0112 0.0989
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0266 0.0491 0.1317
Schistosoma mansoni cell adhesion molecule 0.0175 0.0281 0.0796
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0086 0.0076 0.0669
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0275 0.0513 0.0513
Trichomonas vaginalis AGC family protein kinase 0.0188 0.0311 0.2738
Echinococcus granulosus protein kinase c epsilon type 0.0151 0.0225 0.0637
Schistosoma mansoni serine/threonine protein kinase 0.0092 0.0089 0.0253
Schistosoma mansoni serine/threonine protein kinase 0.0071 0.0042 0.0119
Schistosoma mansoni titin 0.007 0.0038 0.0109
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0103 0.0116 0.031
Schistosoma mansoni serine/threonine protein kinase 0.0163 0.0253 0.0717
Echinococcus granulosus casein kinase I alpha 0.0113 0.0138 0.0391
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.4392 1 1
Echinococcus granulosus calcium activated potassium channel 0.0066 0.0031 0.0088
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0192 0.032 0.0907
Loa Loa (eye worm) hypothetical protein 0.007 0.0038 0.0038
Echinococcus multilocularis serine:threonine protein kinase N2 0.0116 0.0146 0.0392
Schistosoma mansoni tyrosine kinase 0.0871 0.1885 0.5345
Echinococcus granulosus raf serine:threonine protein kinase 0.0086 0.0076 0.0215
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0123 0.0162 0.1428
Schistosoma mansoni cell adhesion molecule 0.007 0.0038 0.0109
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0082 0.0068 0.0068
Schistosoma mansoni serine/threonine protein kinase 0.0189 0.0313 0.0887
Plasmodium falciparum protein kinase 5 0.0164 0.0257 0.2262
Brugia malayi Protein kinase domain containing protein 0.0342 0.0667 0.0667
Brugia malayi SH2 domain containing protein 0.0062 0.002 0.002
Brugia malayi Niemann-Pick C1 protein precursor 0.0119 0.0152 0.0152
Loa Loa (eye worm) TK/FER protein kinase 0.0115 0.0142 0.0142
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0244 0.044 0.1247
Trichomonas vaginalis CAMK family protein kinase 0.0219 0.0383 0.3378
Loa Loa (eye worm) hypothetical protein 0.0159 0.0244 0.0244
Schistosoma mansoni serine/threonine protein kinase 0.0189 0.0313 0.0887
Schistosoma mansoni cell adhesion molecule 0.0072 0.0044 0.0124
Echinococcus multilocularis phosphatidylinositol 3 kinase regulatory subunit 0.0062 0.002 0.0054
Trypanosoma cruzi cdc2-related kinase 1 0.0164 0.0257 0.2262
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0116 0.0146 0.0146
Schistosoma mansoni ephrin receptor 0.0055 0.0005 0.0015
Echinococcus granulosus mitogen activated protein kinase 11 0.0159 0.0243 0.0689
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.007 0.0038 0.0109
Entamoeba histolytica protein kinase, putative 0.0176 0.0284 0.2503
Onchocerca volvulus 0.0134 0.0186 0.0569
Loa Loa (eye worm) hypothetical protein 0.0115 0.0142 0.0142
Schistosoma mansoni serine/threonine protein kinase 0.0066 0.0031 0.0088
Brugia malayi serine/threonine-protein kinase plk-2 0.0219 0.0383 0.0383
Schistosoma mansoni serine/threonine protein kinase 0.0066 0.0031 0.0088
Leishmania major mitogen-activated protein kinase kinase 5, putative;with=GeneDB:LmxM36.0860 0.0114 0.0141 0.1245
Brugia malayi P21-Rho-binding domain containing protein 0.0134 0.0187 0.0187
Trypanosoma cruzi Protein kinase B 0.0108 0.0128 0.1127
Echinococcus multilocularis tyrosine protein kinase shark 0.0115 0.0142 0.0382
Echinococcus multilocularis c src tyrosine kinase 0.0138 0.0195 0.0524
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0106 0.0121 0.0343
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0988 0.2156 0.6112
Schistosoma mansoni protein kinase 0.0518 0.1071 0.3035
Trypanosoma brucei cdc2-related kinase 3 0.0164 0.0257 0.2262
Brugia malayi P38 map kinase family protein 2 0.0159 0.0243 0.0243
Echinococcus multilocularis casein kinase I delta 0.0113 0.0138 0.037
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0545 0.1135 0.1135
Onchocerca volvulus 0.0117 0.0147 0.045
Echinococcus granulosus activin receptor type 0.009 0.0085 0.0242
Schistosoma mansoni shc transforming protein 0.0062 0.002 0.0057
Echinococcus multilocularis casein kinase I alpha 0.0113 0.0138 0.037
Echinococcus granulosus protein kinase c iota type 0.0229 0.0406 0.1151
Loa Loa (eye worm) TK/EGFR protein kinase 0.1583 0.3527 0.3527
Schistosoma mansoni tyrosine kinase 0.0138 0.0195 0.0554
Trypanosoma brucei Casein kinase II 0.0102 0.0112 0.0989
Trichomonas vaginalis STE family protein kinase 0.0192 0.032 0.282
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0189 0.0313 0.0839
Echinococcus multilocularis dual specificity protein kinase clk2 0.0163 0.0253 0.0678
Trichomonas vaginalis CAMK family protein kinase 0.0082 0.0068 0.0595
Entamoeba histolytica protein kinase domain containing protein 0.0102 0.0112 0.0989
Brugia malayi Protein kinase domain containing protein 0.0163 0.0253 0.0253
Brugia malayi Immunoglobulin I-set domain containing protein 0.007 0.0038 0.0038

Activities

Activity type Activity value Assay description Source Reference
EC50 (functional) = 21.157 um PUBCHEM_BIOASSAY: Luminescence Cell-Based Dose Response HTS to Identify Activators of 5'UTR Stem-Loop Driven Prion Protein mRNA Translation in H4 Neuroglioblastoma Cells. (Class of assay: confirmatory) [Related pubchem assays: 1829 (Project Summary), 1814 (Primary HTS)] ChEMBL. No reference
Potency (functional) 0.5858 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) = 2.2387 um PUBCHEM_BIOASSAY: qHTS Assay for NPC1 Promoter Activators. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 2.8184 um PUBCHEM_BIOASSAY: qHTS Assay for Rab9 Promoter Activators. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 10.4179 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 16.3535 uM PUBCHEM_BIOASSAY: qHTS screen for small molecules that inhibit ELG1-dependent DNA repair in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493107, AID493125] ChEMBL. No reference
Potency (functional) 16.9441 uM PUBCHEM_BIOASSAY: qHTS profiling assay for firefly luciferase inhibitor/activator using purified enzyme and Km concentrations of substrates (counterscreen for miR-21 project). (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2288, AID2289, AID2598, AID411] ChEMBL. No reference
Potency (functional) 21.1923 uM PubChem BioAssay. qHTS for Inhibitors of PLK1-PDB (polo-like kinase 1 - polo-box domain): Primary Screen. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 28.1838 uM PUBCHEM_BIOASSAY: Inhibitors of Regulator of G Protein Signaling (RGS) 4: qHTS. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504856] ChEMBL. No reference
Potency (binding) = 39.8107 um PUBCHEM_BIOASSAY: qHTS for Inhibitors of Tau Fibril Formation, Thioflavin T Binding. (Class of assay: confirmatory) [Related pubchem assays: 596 ] ChEMBL. No reference
Potency (functional) 89.1251 uM PUBCHEM_BIOASSAY: Inhibitors of the vitamin D receptor (VDR): qHTS. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504855] ChEMBL. No reference
Potency (functional) 89.1251 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Iota. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588623] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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