Detailed information for compound 132714

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 437.738 | Formula: C18H14BrClN2O2S
  • H donors: 0 H acceptors: 2 LogP: 4.6 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: Brc1ccc(cc1)N(/C(=C/1\C(=O)N(C)c2c(C1=O)cc(cc2)Cl)/S)C
  • InChi: 1S/C18H14BrClN2O2S/c1-21(12-6-3-10(19)4-7-12)18(25)15-16(23)13-9-11(20)5-8-14(13)22(2)17(15)24/h3-9,25H,1-2H3/b18-15+
  • InChiKey: VKLJNYBWNTWOAT-OBGWFSINSA-N  


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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0009 0.0032 0.0611
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0008 0.0025 0.0025
Mycobacterium tuberculosis Conserved hypothetical protein 0.0023 0.0204 0.1222
Toxoplasma gondii carbonyl reductase 1, putative 0.0009 0.0032 0.0611
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0015 0.0101 0.035
Echinococcus multilocularis rhodopsin orphan GPCR 0.0008 0.0025 0.0025
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0008 0.0025 0.0025
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0116 0.041
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0008 0.0025 0.0025
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0008 0.0025 0.0025
Plasmodium falciparum oxidoreductase, short-chain dehydrogenase family, putative 0.0009 0.0032 0.0707
Giardia lamblia Oxidoreductase, short chain dehydrogenase/reductase family 0.0009 0.0032 0.0087
Entamoeba histolytica serine/threonine protein kinase, putative 0.0221 0.2618 1
Loa Loa (eye worm) hypothetical protein 0.0012 0.007 0.0233
Echinococcus granulosus tm gpcr rhodopsin 0.0008 0.0025 0.0025
Entamoeba histolytica deoxycytidyl transferase, putative 0.0023 0.0204 0.0664
Echinococcus granulosus rhodopsin orphan GPCR 0.0008 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0008 0.0025 0.0082
Echinococcus granulosus carbonyl reductase 1 0.0009 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0008 0.0025 0.0082
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0009 0.0032 0.0087
Echinococcus multilocularis G-protein coupled receptor, putative 0.0008 0.0025 0.0025
Loa Loa (eye worm) oxidoreductase 0.0009 0.0032 0.0108
Schistosoma mansoni amine GPCR 0.0008 0.0025 0.0025
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0009 0.0032 0.0611
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0012 0.007 0.007
Mycobacterium ulcerans short chain dehydrogenase 0.0009 0.0032 0.0159
Brugia malayi MH1 domain containing protein 0.0009 0.0035 0.0118
Echinococcus granulosus mothers against decapentaplegic 5 0.0009 0.0035 0.0035
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0008 0.0025 0.0025
Loa Loa (eye worm) oxidoreductase 0.0009 0.0032 0.0108
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0012 0.007 0.0232
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0011 0.006 0.006
Trypanosoma cruzi hypothetical protein, conserved 0.0009 0.0032 0.0087
Schistosoma mansoni oxidoreductase short chain dehydrogenase/reductase family 0.0009 0.0032 0.0032
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0009 0.0032 0.0159
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0009 0.0032 0.0107
Trypanosoma brucei 3-ketoacyl-CoA reductase, putative 0.0009 0.0032 0.0087
Schistosoma mansoni myosin xvIII 0.0008 0.0025 0.0025
Onchocerca volvulus 0.0009 0.0032 0.0024
Brugia malayi MH1 domain containing protein 0.0009 0.0035 0.0118
Loa Loa (eye worm) oxidoreductase 0.0009 0.0032 0.0108
Schistosoma mansoni short chain dehydrogenase 0.0009 0.0032 0.0032
Brugia malayi larval opioid receptor 0.0008 0.0025 0.0082
Leishmania major short chain dehydrogenase/reductase, putative 0.0009 0.0032 0.0087
Mycobacterium ulcerans 3-alpha-hydroxysteroid dehydrogenase 0.0009 0.0032 0.0159
Loa Loa (eye worm) neuropeptide F receptor 0.0008 0.0025 0.0082
Schistosoma mansoni short chain dehydrogenase 0.0009 0.0032 0.0032
Echinococcus multilocularis carbonyl reductase 1 0.0009 0.0032 0.0032
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0009 0.0032 0.0087
Echinococcus multilocularis 3 ketodihydrosphingosine reductase 0.0009 0.0032 0.0032
Brugia malayi G-protein coupled receptor 0.0008 0.0025 0.0082
Echinococcus multilocularis neuropeptide Y receptor 0.0008 0.0025 0.0025
Echinococcus multilocularis mothers against decapentaplegic 5 0.0009 0.0035 0.0035
Brugia malayi MH2 domain containing protein 0.0009 0.0035 0.0118
Loa Loa (eye worm) latrophilin receptor protein 2 0.0037 0.0372 0.1246
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0009 0.0032 0.0107
Leishmania major DNA polymerase kappa, putative 0.0023 0.0204 0.0745
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0034 0.0338 0.8831
Echinococcus multilocularis g protein coupled receptor 0.0008 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0009 0.0032 0.0108
Schistosoma mansoni DNA helicase recq1 0.0011 0.006 0.006
Loa Loa (eye worm) hypothetical protein 0.0054 0.0576 0.1928
Leishmania major ATP-dependent phosphofructokinase 0.0124 0.1437 0.5472
Echinococcus granulosus TGF beta signal transducer SmadC 0.0009 0.0035 0.0035
Schistosoma mansoni short chain dehydrogenase 0.0009 0.0032 0.0032
Schistosoma mansoni steroid dehydrogenase 0.0009 0.0032 0.0032
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0008 0.0025 0.0082
Mycobacterium ulcerans DNA polymerase IV 0.0023 0.0204 0.1362
Loa Loa (eye worm) hypothetical protein 0.0008 0.0025 0.0082
Leishmania major short chain dehydrogenase, putative 0.0009 0.0032 0.0087
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0008 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0008 0.0025 0.0082
Toxoplasma gondii 3-ketoacyl-CoA reductase, putative 0.0009 0.0032 0.0611
Onchocerca volvulus 0.0009 0.0032 0.0024
Echinococcus granulosus neuropeptides capa receptor 0.0008 0.0025 0.0025
Trypanosoma brucei unspecified product 0.0023 0.0204 0.0745
Leishmania major 3-keto-dihydrosphingosine reductase 0.0009 0.0032 0.0087
Loa Loa (eye worm) hypothetical protein 0.0008 0.0025 0.0082
Schistosoma mansoni opsin-like receptor 0.0008 0.0025 0.0025
Schistosoma mansoni hypothetical protein 0.0037 0.0372 0.0372
Wolbachia endosymbiont of Brugia malayi bacterioferritin/cytochrome b1 0.001 0.004 1
Schistosoma mansoni short chain dehydrogenase 0.0009 0.0032 0.0032
Leishmania major short chain dehydrogenase-like protein 0.0009 0.0032 0.0087
Brugia malayi hypothetical protein 0.0008 0.0025 0.0082
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0012 0.007 0.0232
Brugia malayi Bloom's syndrome protein homolog 0.0027 0.0257 0.0854
Trypanosoma brucei unspecified product 0.0016 0.0116 0.041
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0011 0.006 0.02
Echinococcus multilocularis rhodopsin orphan GPCR 0.0008 0.0025 0.0025
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0009 0.0032 0.0107
Echinococcus granulosus g protein coupled receptor 0.0008 0.0025 0.0025
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0008 0.0025 0.0082
Echinococcus multilocularis Smad4 0.0009 0.0035 0.0035
Onchocerca volvulus 0.0009 0.0032 0.0024
Echinococcus multilocularis rhodopsin orphan GPCR 0.0008 0.0025 0.0025
Echinococcus multilocularis neuropeptides capa receptor 0.0008 0.0025 0.0025
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0221 0.2618 0.2618
Trichomonas vaginalis phosphofructokinase, putative 0.0124 0.1437 0.4402
Leishmania major DNA polymerase eta, putative 0.0038 0.0382 0.1426
Mycobacterium leprae PROBABLE BACTERIOFERRITIN BFRA 0.001 0.004 0.0056
Echinococcus granulosus oxidoreductase 0.0009 0.0032 0.0032
Trypanosoma cruzi short chain dehydrogenase, putative 0.0009 0.0032 0.0087
Echinococcus granulosus GPCR family 2 0.0037 0.0372 0.0372
Loa Loa (eye worm) hypothetical protein 0.0008 0.0025 0.0082
Echinococcus multilocularis rhodopsin orphan GPCR 0.0008 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0008 0.0025 0.0082
Echinococcus granulosus sex peptide receptor 0.0008 0.0025 0.0025
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0009 0.0032 0.0159
Echinococcus granulosus neuropeptide s receptor 0.056 0.6743 0.6743
Mycobacterium ulcerans short chain dehydrogenase 0.0009 0.0032 0.0159
Echinococcus granulosus neuropeptide Y receptor 0.0008 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0008 0.0025 0.0082
Loa Loa (eye worm) neuropeptide F receptor 0.0008 0.0025 0.0082
Leishmania major quinonoid dihydropteridine reductase 0.0009 0.0032 0.0087
Brugia malayi serine/threonine-protein kinase plk-2 0.0221 0.2618 0.8719
Leishmania major quinonoid dihydropteridine reductase 0.0009 0.0032 0.0087
Loa Loa (eye worm) hypothetical protein 0.0008 0.0025 0.0082
Schistosoma mansoni opsin-like receptor 0.0008 0.0025 0.0025
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0012 0.007 0.0232
Trypanosoma brucei DNA polymerase eta, putative 0.0054 0.0576 0.2171
Echinococcus multilocularis transcription factor eb 0.0253 0.3003 0.3003
Loa Loa (eye worm) oxidoreductase 0.0009 0.0032 0.0108
Brugia malayi Steroid receptor seven-up type 2 0.0012 0.007 0.0232
Echinococcus granulosus histone lysine methyltransferase setb 0.0034 0.0338 0.0338
Onchocerca volvulus 0.0012 0.007 0.0141
Loa Loa (eye worm) 6-phosphofructokinase 0.0124 0.1437 0.4809
Schistosoma mansoni smad1 5 8 and 0.0009 0.0035 0.0035
Echinococcus granulosus G protein coupled receptor 139 0.0008 0.0025 0.0025
Echinococcus multilocularis rhodopsin orphan GPCR 0.0008 0.0025 0.0025
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0034 0.0331 1
Toxoplasma gondii 2,4-dienoyl CoA reductase 2, peroxisomal family protein 0.0009 0.0032 0.0611
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0009 0.0032 0.0611
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0009 0.0032 0.0611
Trypanosoma brucei short-chain dehydrogenase, putative 0.0009 0.0032 0.0087
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0009 0.0032 0.0107
Echinococcus multilocularis estradiol 17 beta dehydrogenase 12 0.0009 0.0032 0.0032
Toxoplasma gondii oxidoreductase, putative 0.0009 0.0032 0.0611
Loa Loa (eye worm) hypothetical protein 0.0008 0.0025 0.0082
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0008 0.0025 0.0025
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0117 0.1345 0.4501
Loa Loa (eye worm) hypothetical protein 0.0008 0.0025 0.0082
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.0009 0.0032 0.0087
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0034 0.0331 0.1156
Onchocerca volvulus 0.0009 0.0032 0.0024
Echinococcus granulosus carbonyl reductase 1 0.0009 0.0032 0.0032
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0009 0.0032 0.0087
Mycobacterium ulcerans short-chain dehydrogenase 0.0009 0.0032 0.0159
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0009 0.0032 0.0107
Echinococcus granulosus biogenic amine 5HT receptor 0.0008 0.0025 0.0025
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0204 0.0745
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0009 0.0032 0.0107
Mycobacterium ulcerans oxidoreductase 0.0009 0.0032 0.0159
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0012 0.007 0.007
Entamoeba histolytica recQ family helicase, putative 0.0015 0.0101 0.0265
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0204 0.0745
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0204 0.0745
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0009 0.0032 0.0032
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0023 0.0204 0.1222
Brugia malayi hypothetical protein 0.0009 0.0032 0.0107
Brugia malayi putative neuropeptide receptor 0.0008 0.0025 0.0082
Trichomonas vaginalis phosphofructokinase, putative 0.0034 0.0331 0.0937
Brugia malayi G-protein coupled receptor 0.0008 0.0025 0.0082
Loa Loa (eye worm) hypothetical protein 0.0009 0.0032 0.0108
Trichomonas vaginalis phosphofructokinase, putative 0.0034 0.0331 0.0937
Schistosoma mansoni coup transcription factor 0.0012 0.007 0.007
Loa Loa (eye worm) hypothetical protein 0.0008 0.0025 0.0082
Leishmania major short chain dehydrogenase, putative 0.0009 0.0032 0.0087
Onchocerca volvulus 0.0009 0.0032 0.0024
Mycobacterium ulcerans short chain dehydrogenase 0.0009 0.0032 0.0159
Brugia malayi polk-prov protein 0.0007 0.001 0.0032
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0012 0.007 0.0232
Schistosoma mansoni apoferritin-2 0.001 0.004 0.004
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0009 0.0032 0.0159
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0011 0.006 0.1573
Brugia malayi Tachykinin-like peptides receptor 99D 0.0008 0.0025 0.0082
Trichomonas vaginalis phosphofructokinase, putative 0.0124 0.1437 0.4402
Loa Loa (eye worm) hypothetical protein 0.0008 0.0025 0.0082
Mycobacterium ulcerans short chain dehydrogenase 0.0009 0.0032 0.0159
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.0338 0.0338
Loa Loa (eye worm) hypothetical protein 0.0008 0.0025 0.0082
Brugia malayi Dopamine receptor 0.0008 0.0025 0.0082
Loa Loa (eye worm) hypothetical protein 0.0008 0.0025 0.0082
Schistosoma mansoni neuropeptide receptor 0.0008 0.0025 0.0025
Giardia lamblia Reductase, putative 0.0009 0.0032 0.0087
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0008 0.0025 0.0025
Mycobacterium ulcerans ketoacyl reductase 0.0009 0.0032 0.0159
Loa Loa (eye worm) hypothetical protein 0.0008 0.0025 0.0082
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0008 0.0025 0.0025
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0012 0.007 0.007
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0008 0.0025 0.0025
Onchocerca volvulus 0.0009 0.0032 0.0024
Leishmania major hypothetical protein, conserved 0.0009 0.0032 0.0087
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0012 0.007 0.007
Echinococcus multilocularis g protein coupled receptor 0.0008 0.0025 0.0025
Brugia malayi photoreceptor-specific nuclear receptor 0.0012 0.007 0.0232
Loa Loa (eye worm) hypothetical protein 0.0008 0.0025 0.0082
Loa Loa (eye worm) hypothetical protein 0.0012 0.007 0.0233
Echinococcus multilocularis carbonyl reductase 1 0.0009 0.0032 0.0032
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0008 0.0025 0.0025
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0008 0.0025 0.0082
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0008 0.0025 0.0025
Brugia malayi MH2 domain containing protein 0.0009 0.0035 0.0118
Schistosoma mansoni carbonyl reductase 0.0009 0.0032 0.0032
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0008 0.0025 0.0082
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0008 0.0025 0.0025
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0009 0.0032 0.0159
Trichomonas vaginalis CAMK family protein kinase 0.0221 0.2618 0.8103
Trypanosoma cruzi DNA polymerase kappa, putative 0.0023 0.0204 0.0745
Echinococcus granulosus neuropeptide receptor 0.0008 0.0025 0.0025
Echinococcus multilocularis g-protein coupled receptor 0.0008 0.0025 0.0025
Mycobacterium ulcerans short chain dehydrogenase 0.0009 0.0032 0.0159
Leishmania major hypothetical protein, conserved 0.0009 0.0032 0.0087
Trypanosoma brucei beta-ketoacyl-ACP reductase 2 0.0009 0.0032 0.0087
Schistosoma mansoni carbonyl reductase 0.0009 0.0032 0.0032
Brugia malayi dehydrogenases, short chain protein 9 0.0009 0.0032 0.0107
Mycobacterium ulcerans short-chain dehydrogenase 0.0009 0.0032 0.0159
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0009 0.0032 0.0707
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0008 0.0025 0.0025
Trypanosoma cruzi DNA polymerase eta, putative 0.0054 0.0576 0.2171
Schistosoma mansoni terminal deoxycytidyl transferase 0.0023 0.0204 0.0204
Echinococcus multilocularis dro:myosuppressin receptor 0.0008 0.0025 0.0025
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0012 0.007 0.007
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0012 0.007 0.007
Schistosoma mansoni 3-keto-dihydrosphingosine reductase 0.0009 0.0032 0.0032
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0012 0.007 0.0232
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0012 0.007 0.0232
Loa Loa (eye worm) hypothetical protein 0.0008 0.0025 0.0082
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.0009 0.0032 0.0087
Schistosoma mansoni nuclear hormone receptor 0.0012 0.007 0.007
Echinococcus multilocularis G protein coupled receptor 139 0.0008 0.0025 0.0025
Mycobacterium ulcerans short chain dehydrogenase 0.0009 0.0032 0.0159
Trichomonas vaginalis phosphofructokinase, putative 0.0034 0.0331 0.0937
Loa Loa (eye worm) hypothetical protein 0.0008 0.0025 0.0082
Plasmodium vivax 6-phosphofructokinase, putative 0.0034 0.0331 0.9794
Trypanosoma brucei oxidoreductase-like protein 0.0009 0.0032 0.0087
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0221 0.2618 0.2618
Brugia malayi Pre-SET motif family protein 0.0238 0.2822 0.94
Schistosoma mansoni steroid dehydrogenase 0.0009 0.0032 0.0032
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0037 0.0372 0.124
Trypanosoma brucei short-chain dehydrogenase, putative 0.0009 0.0032 0.0087
Schistosoma mansoni alpha-1 adrenergic receptor 0.0008 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0007 0.001 0.0032
Mycobacterium ulcerans short chain dehydrogenase 0.0009 0.0032 0.0159
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.0338 0.0338
Mycobacterium ulcerans short chain dehydrogenase 0.0009 0.0032 0.0159
Loa Loa (eye worm) hypothetical protein 0.0008 0.0025 0.0082
Echinococcus granulosus g protein coupled receptor 0.0008 0.0025 0.0025
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0009 0.0032 0.0107
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0012 0.007 0.0232
Echinococcus granulosus hypothetical protein 0.0009 0.0032 0.0032
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.0009 0.0032 0.0087
Echinococcus granulosus ecdysone induced protein 78C 0.0012 0.007 0.007
Brugia malayi Dehydrogenases, short chain protein 30 0.0009 0.0032 0.0107
Schistosoma mansoni biogenic amine (5HT) receptor 0.0008 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0011 0.006 0.0201
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 1 homolog 0.0009 0.0032 0.0024
Trichomonas vaginalis CAMK family protein kinase 0.011 0.1257 0.3837
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0009 0.0032 0.0107
Schistosoma mansoni ferritin 0.001 0.004 0.004
Trichomonas vaginalis phosphofructokinase, putative 0.0124 0.1437 0.4402
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0116 0.041
Loa Loa (eye worm) hypothetical protein 0.0012 0.007 0.0233
Loa Loa (eye worm) hypothetical protein 0.0008 0.0025 0.0082
Loa Loa (eye worm) hypothetical protein 0.0008 0.0025 0.0082
Loa Loa (eye worm) hypothetical protein 0.0117 0.1345 0.4501
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0037 0.0372 0.0372
Echinococcus granulosus hypothetical protein 0.0008 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0037 0.0372 0.1246
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0124 0.1437 1
Loa Loa (eye worm) hypothetical protein 0.008 0.0895 0.2994
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0008 0.0025 0.0025
Brugia malayi Serotonin receptor 0.0008 0.0025 0.0082
Trichomonas vaginalis DNA helicase recq1, putative 0.0027 0.0257 0.0703
Schistosoma mansoni steroid dehydrogenase 0.0009 0.0032 0.0032
Trichomonas vaginalis CAMK family protein kinase 0.0221 0.2618 0.8103
Schistosoma mansoni growth hormone secretagogue receptor 0.0008 0.0025 0.0025
Brugia malayi putative neuropeptide receptor NPR1 0.0008 0.0025 0.0082
Schistosoma mansoni hypothetical protein 0.0008 0.0025 0.0025
Loa Loa (eye worm) TYRA-2 protein 0.0008 0.0025 0.0082
Echinococcus granulosus peptide allatostatin:somatostatin 0.0008 0.0025 0.0025
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0008 0.0025 0.0025
Schistosoma mansoni short chain dehydrogenase 0.0009 0.0032 0.0032
Onchocerca volvulus 0.0034 0.0338 0.098
Trypanosoma cruzi polo-like protein kinase, putative 0.0221 0.2618 1
Loa Loa (eye worm) hypothetical protein 0.0009 0.0032 0.0108
Echinococcus multilocularis steroid dehydrogenase 0.0009 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0008 0.0025 0.0082
Loa Loa (eye worm) hypothetical protein 0.0008 0.0025 0.0082
Schistosoma mansoni thyroid hormone receptor 0.0012 0.007 0.007
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0008 0.0025 0.0025
Schistosoma mansoni steroid hormone receptor ad4bp 0.0012 0.007 0.007
Echinococcus multilocularis microtubule associated protein 2 0.0828 1 1
Schistosoma mansoni steroid dehydrogenase 0.0009 0.0032 0.0032
Schistosoma mansoni ferritin light chain 0.001 0.004 0.004
Toxoplasma gondii oxidoreductase, putative 0.0009 0.0032 0.0611
Schistosoma mansoni microtubule-associated protein tau 0.0828 1 1
Trypanosoma brucei short-chain dehydrogenase, putative 0.0009 0.0032 0.0087
Echinococcus granulosus 3 ketodihydrosphingosine reductase 0.0009 0.0032 0.0032
Brugia malayi AKH receptor 0.0008 0.0025 0.0082
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0012 0.007 0.007
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0009 0.0032 0.0159
Echinococcus multilocularis somatostatin receptor 0.0008 0.0025 0.0025
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0023 0.0204 0.0204
Schistosoma mansoni neuropeptide receptor 0.0008 0.0025 0.0025
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0008 0.0025 0.0025
Mycobacterium ulcerans short chain dehydrogenase 0.0009 0.0032 0.0159
Mycobacterium ulcerans short chain dehydrogenase 0.0009 0.0032 0.0159
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0012 0.007 0.0232
Loa Loa (eye worm) RecQ helicase 0.0027 0.0257 0.0859
Loa Loa (eye worm) hypothetical protein 0.0009 0.0032 0.0108
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0034 0.0331 0.5
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0008 0.0025 0.0025
Loa Loa (eye worm) steroid hormone receptor 0.0012 0.007 0.0233
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0204 0.0745
Schistosoma mansoni steroid dehydrogenase 0.0009 0.0032 0.0032
Echinococcus granulosus hypothetical protein 0.0009 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0008 0.0025 0.0082
Brugia malayi neuropeptide F receptor 0.0008 0.0025 0.0082
Loa Loa (eye worm) dehydrogenase 0.0009 0.0032 0.0108
Brugia malayi Pre-SET motif family protein 0.0034 0.0338 0.1126
Echinococcus granulosus expressed protein 0.001 0.004 0.004
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0012 0.007 0.007
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0009 0.0032 0.0107
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0012 0.007 0.007
Echinococcus multilocularis retinol dehydrogenase 11 0.0009 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0008 0.0025 0.0082
Loa Loa (eye worm) hypothetical protein 0.0009 0.0032 0.0108
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0008 0.0025 0.0025
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0008 0.0025 0.0082
Loa Loa (eye worm) transcription factor SMAD2 0.0137 0.1586 0.5308
Echinococcus granulosus retinol dehydrogenase 11 0.0009 0.0032 0.0032
Giardia lamblia Sgs1 DNA helicase, putative 0.0011 0.006 0.0194
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0204 0.0745
Schistosoma mansoni steroid dehydrogenase 0.0009 0.0032 0.0032
Giardia lamblia Kinase, PLK 0.0221 0.2618 1
Mycobacterium ulcerans bacterioferritin BfrA 0.001 0.004 0.0215
Onchocerca volvulus Sepiapterin reductase homolog 0.0009 0.0032 0.0024
Mycobacterium ulcerans DNA polymerase IV 0.0023 0.0204 0.1362
Brugia malayi steroid hormone receptor 0.0012 0.007 0.0232
Brugia malayi hypothetical protein 0.0008 0.0025 0.0082
Schistosoma mansoni hypothetical protein 0.0037 0.0372 0.0372
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0011 0.006 0.006
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.0009 0.0032 0.0024
Schistosoma mansoni ferritin 0.001 0.004 0.004
Schistosoma mansoni carbonyl reductase 0.0009 0.0032 0.0032
Mycobacterium ulcerans ketoacyl reductase 0.0009 0.0032 0.0159
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0012 0.007 0.0233
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0012 0.007 0.0233
Trypanosoma cruzi short-chain dehydrogenase, putative 0.0009 0.0032 0.0087
Schistosoma mansoni hypothetical protein 0.0037 0.0372 0.0372
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0023 0.0204 0.0204
Mycobacterium ulcerans short chain dehydrogenase 0.0009 0.0032 0.0159
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0008 0.0025 0.0082
Onchocerca volvulus Bile acid receptor homolog 0.0012 0.007 0.0141
Loa Loa (eye worm) hypothetical protein 0.0008 0.0025 0.0082
Brugia malayi phosphofructokinase 0.0124 0.1437 0.4785
Loa Loa (eye worm) oxidoreductase 0.0009 0.0032 0.0108
Brugia malayi neuropeptide F receptor 0.0008 0.0025 0.0082
Onchocerca volvulus 0.0009 0.0032 0.0024
Schistosoma mansoni short chain dehydrogenase 0.0009 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0012 0.007 0.0233
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0012 0.007 0.007
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.0009 0.0032 0.0087
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0117 0.1345 0.4479
Echinococcus granulosus rhodopsin orphan GPCR 0.0008 0.0025 0.0025
Schistosoma mansoni biogenic amine receptor 0.0008 0.0025 0.0025
Echinococcus multilocularis fmrfamide receptor 0.0008 0.0025 0.0025
Onchocerca volvulus 0.0009 0.0032 0.0024
Schistosoma mansoni ferritin 0.001 0.004 0.004
Echinococcus multilocularis neuropeptide receptor A26 0.056 0.6743 0.6743
Loa Loa (eye worm) hypothetical protein 0.0009 0.0032 0.0108
Brugia malayi GnHR receptor homolog 0.0008 0.0025 0.0082
Schistosoma mansoni neuropeptide f receptor 76f 0.0008 0.0025 0.0025
Loa Loa (eye worm) TAR-binding protein 0.0073 0.0805 0.2694
Trypanosoma cruzi hypothetical protein, conserved 0.0009 0.0032 0.0087
Trichomonas vaginalis CAMK family protein kinase 0.0221 0.2618 0.8103
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0008 0.0025 0.0025
Echinococcus multilocularis bloom syndrome protein 0.0027 0.0257 0.0257
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0009 0.0032 0.0107
Mycobacterium ulcerans short chain dehydrogenase 0.0009 0.0032 0.0159
Brugia malayi ORL1-like opioid receptor 0.0008 0.0025 0.0082
Echinococcus multilocularis orexin receptor type 2 0.0008 0.0025 0.0025
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0009 0.0032 0.0159
Leishmania major hypothetical protein, conserved 0.0009 0.0032 0.0087
Brugia malayi oxidoreductase 0.0009 0.0032 0.0107
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0034 0.0331 1
Loa Loa (eye worm) G-protein coupled receptor 0.0008 0.0025 0.0082
Loa Loa (eye worm) hypothetical protein 0.0012 0.007 0.0233
Onchocerca volvulus 0.0271 0.3223 1
Schistosoma mansoni neuropeptide F-like receptor 0.0008 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0009 0.0032 0.0108
Echinococcus multilocularis neuropeptide FF receptor 2 0.0008 0.0025 0.0025
Echinococcus granulosus ferritin 0.001 0.004 0.004
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0034 0.0338 0.0338
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0008 0.0025 0.0025
Trypanosoma cruzi quinonoid dihydropteridine reductase, putative 0.0009 0.0032 0.0087
Brugia malayi Calcitonin receptor-like protein seb-1 0.0117 0.1345 0.4479
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0033 0.0323 0.0323
Loa Loa (eye worm) hypothetical protein 0.0008 0.0025 0.0082
Echinococcus multilocularis rhodopsin orphan GPCR 0.0008 0.0025 0.0025
Trypanosoma brucei beta-D-hydroxybutyrate dehydrogenase 0.0009 0.0032 0.0087
Brugia malayi sulfakinin receptor protein 0.0008 0.0025 0.0082
Loa Loa (eye worm) hypothetical protein 0.0012 0.007 0.0233
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0012 0.007 0.0232
Loa Loa (eye worm) hypothetical protein 0.0008 0.0025 0.0082
Echinococcus multilocularis dna polymerase kappa 0.0023 0.0204 0.0204
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0204 0.0745
Leishmania major dehydrogenase-like protein 0.0009 0.0032 0.0087
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0018 0.0146 0.3657
Schistosoma mansoni smad1 5 8 and 0.0009 0.0035 0.0035
Brugia malayi hypothetical protein 0.0008 0.0025 0.0082
Echinococcus granulosus rhodopsin orphan GPCR 0.0008 0.0025 0.0025
Echinococcus granulosus tm gpcr rhodopsin 0.0008 0.0025 0.0025
Mycobacterium ulcerans short chain dehydrogenase 0.0009 0.0032 0.0159
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0009 0.0035 0.0035
Trichomonas vaginalis set domain proteins, putative 0.0271 0.3223 1
Brugia malayi ImpB/MucB/SamB family protein 0.0023 0.0204 0.0679
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0008 0.0025 0.0082
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.0009 0.0032 0.0087
Leishmania major quinonoid dihydropteridine reductase 0.0009 0.0032 0.0087
Giardia lamblia Short-chain dehydrogenase, putative 0.0009 0.0032 0.0087
Loa Loa (eye worm) oxidoreductase 0.0009 0.0032 0.0108
Onchocerca volvulus Protein ultraspiracle homolog 0.0012 0.007 0.0141
Echinococcus granulosus epidermal retinal dehydrogenase 2 0.0009 0.0032 0.0032
Brugia malayi Smad1 0.0009 0.0035 0.0118
Trypanosoma brucei short-chain dehydrogenase, putative 0.0009 0.0032 0.0087
Schistosoma mansoni hypothetical protein 0.0008 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0009 0.0032 0.0108
Brugia malayi hypothetical protein 0.0008 0.0025 0.0082
Loa Loa (eye worm) hypothetical protein 0.0008 0.0025 0.0082
Echinococcus multilocularis serotonin receptor 0.0008 0.0025 0.0025
Echinococcus multilocularis ecdysone induced protein 78C 0.0012 0.007 0.007
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0034 0.0331 0.8649
Schistosoma mansoni amine GPCR 0.0008 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0008 0.0025 0.0082
Brugia malayi 6-phosphofructokinase 0.0124 0.1437 0.4785
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0116 0.041
Trichomonas vaginalis ferritin, putative 0.001 0.004 0.0025
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0008 0.0025 0.0025
Mycobacterium ulcerans 6-phosphofructokinase 0.0124 0.1437 1
Loa Loa (eye worm) hypothetical protein 0.0008 0.0025 0.0082
Echinococcus multilocularis retinol dehydrogenase 13 0.0009 0.0032 0.0032
Schistosoma mansoni neuropeptide receptor 0.0008 0.0025 0.0025
Echinococcus multilocularis conserved hypothetical protein 0.0009 0.0032 0.0032
Mycobacterium ulcerans short chain dehydrogenase 0.0009 0.0032 0.0159
Echinococcus granulosus dna polymerase eta 0.0054 0.0576 0.0576
Brugia malayi hypothetical protein 0.0008 0.0025 0.0082
Schistosoma mansoni serine/threonine protein kinase 0.0221 0.2618 0.2618
Loa Loa (eye worm) hypothetical protein 0.0008 0.0025 0.0082
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0008 0.0025 0.0025
Brugia malayi latrophilin 2 splice variant baaae 0.008 0.0895 0.2979
Trichomonas vaginalis CAMK family protein kinase 0.0221 0.2618 0.8103
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.0009 0.0032 0.0087
Leishmania major pteridine reductase 1 0.0009 0.0032 0.0087
Schistosoma mansoni thyroid hormone receptor 0.0012 0.007 0.007
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0008 0.0025 0.0025
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0012 0.007 0.007
Trypanosoma brucei beta-ketoacyl-ACP reductase 3, putative 0.0009 0.0032 0.0087
Echinococcus granulosus tachykinin peptides receptor 99D 0.0008 0.0025 0.0025
Plasmodium vivax 6-phosphofructokinase, putative 0.0034 0.0331 0.9794
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0221 0.2618 0.8762
Mycobacterium ulcerans carveol-like dehydrogenase 0.0009 0.0032 0.0159
Echinococcus granulosus biogenic amine 5HT receptor 0.0008 0.0025 0.0025
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0012 0.007 0.0232
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0034 0.0331 0.2084
Schistosoma mansoni biogenic amine (5HT) receptor 0.0008 0.0025 0.0025
Echinococcus granulosus neuropeptides capa receptor 0.0008 0.0025 0.0025
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0023 0.0204 0.0682
Loa Loa (eye worm) hypothetical protein 0.0008 0.0025 0.0082
Schistosoma mansoni DNA polymerase eta 0.0054 0.0576 0.0576
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0008 0.0025 0.0025
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0009 0.0035 0.0035
Loa Loa (eye worm) short chain dehydrogenase/reductase family oxidoreductase 0.0009 0.0032 0.0108
Echinococcus granulosus steroid dehydrogenase 0.0009 0.0032 0.0032
Brugia malayi hypothetical protein 0.0008 0.0025 0.0082
Loa Loa (eye worm) phosphofructokinase 0.0124 0.1437 0.4809
Echinococcus multilocularis smad 0.0009 0.0035 0.0035
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0204 0.0745
Mycobacterium ulcerans short chain dehydrogenase 0.0009 0.0032 0.0159
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0008 0.0025 0.0025
Trypanosoma cruzi DNA polymerase kappa, putative 0.0023 0.0204 0.0745
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0204 0.0745
Schistosoma mansoni short chain dehydrogenase 0.0009 0.0032 0.0032
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0009 0.0032 0.0107
Brugia malayi MH2 domain containing protein 0.0137 0.1586 0.5281
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0012 0.007 0.0232
Schistosoma mansoni neuropeptide receptor 0.0008 0.0025 0.0025
Mycobacterium ulcerans dehydrogenase/decarboxylase protein 0.0009 0.0032 0.0159
Echinococcus multilocularis transient receptor potential cation channel 0.0009 0.0032 0.0032
Brugia malayi Dopamine receptor protein 2 0.0008 0.0025 0.0082
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0009 0.0032 0.0159
Schistosoma mansoni biogenic amine receptor 0.0008 0.0025 0.0025
Schistosoma mansoni amine GPCR 0.0008 0.0025 0.0025
Brugia malayi Nuclear hormone receptor-like 1 0.0012 0.007 0.0232
Echinococcus multilocularis dna polymerase eta 0.0054 0.0576 0.0576
Trichomonas vaginalis CAMK family protein kinase 0.0221 0.2618 0.8103
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0008 0.0025 0.0025
Leishmania major hypothetical protein, conserved 0.0009 0.0032 0.0087
Brugia malayi nuclear receptor NHR-88 0.0012 0.007 0.0232
Loa Loa (eye worm) hypothetical protein 0.0008 0.0025 0.0082
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0238 0.2822 0.9447
Echinococcus granulosus FTZ F1 alpha 0.0012 0.007 0.007
Toxoplasma gondii phosphofructokinase PFKII 0.0034 0.0331 0.8649
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0011 0.006 0.0201
Loa Loa (eye worm) MH2 domain-containing protein 0.0137 0.1586 0.5308
Echinococcus multilocularis g protein coupled receptor 0.0008 0.0025 0.0025
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0034 0.0338 0.0338
Trypanosoma cruzi DNA polymerase kappa, putative 0.0023 0.0204 0.0745
Onchocerca volvulus Serine\/threonine kinase homolog 0.0221 0.2618 0.8108
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.0009 0.0032 0.0024
Loa Loa (eye worm) hypothetical protein 0.0009 0.0032 0.0108
Trichomonas vaginalis phosphofructokinase, putative 0.0034 0.0331 0.0937
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0012 0.007 0.0233
Mycobacterium ulcerans ketoacyl reductase 0.0009 0.0032 0.0159
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0008 0.0025 0.0082
Echinococcus granulosus fmrfamide receptor 0.0008 0.0025 0.0025
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.0009 0.0032 0.0087
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0009 0.0032 0.0107
Echinococcus granulosus carbonyl reductase 1 0.0009 0.0032 0.0032
Echinococcus multilocularis neuropeptide s receptor 0.056 0.6743 0.6743
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0009 0.0032 0.0107
Leishmania major quinonoid dihydropteridine reductase 0.0009 0.0032 0.0087
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.001 0.004 0.0056
Mycobacterium ulcerans short chain dehydrogenase 0.0009 0.0032 0.0159
Plasmodium falciparum steroid dehydrogenase, putative 0.0009 0.0032 0.0707
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0012 0.007 0.0232
Trypanosoma brucei DNA polymerase IV, putative 0.0023 0.0204 0.0745
Schistosoma mansoni neuropeptide F-like receptor 0.0008 0.0025 0.0025
Mycobacterium ulcerans oxidoreductase 0.0009 0.0032 0.0159
Trypanosoma cruzi short-chain dehydrogenase, putative 0.0009 0.0032 0.0087
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0009 0.0032 0.0159
Echinococcus granulosus tm gpcr rhodopsin 0.0008 0.0025 0.0025
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0221 0.2618 1
Schistosoma mansoni smad 0.0009 0.0035 0.0035
Schistosoma mansoni 6-phosphofructokinase 0.0124 0.1437 0.1437
Schistosoma mansoni tar DNA-binding protein 0.0073 0.0805 0.0805
Brugia malayi Retinol dehydrogenase 12 0.0009 0.0032 0.0107
Echinococcus granulosus rhodopsin orphan GPCR 0.0008 0.0025 0.0025
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0012 0.007 0.007
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0009 0.0032 0.0159
Brugia malayi follicle stimulating hormone receptor 0.0008 0.0025 0.0082
Echinococcus granulosus rhodopsin orphan GPCR 0.0008 0.0025 0.0025
Echinococcus multilocularis neuropeptide receptor 0.0008 0.0025 0.0025
Schistosoma mansoni short chain dehydrogenase 0.0009 0.0032 0.0032
Trypanosoma cruzi hypothetical protein, conserved 0.0009 0.0032 0.0087
Trypanosoma cruzi DNA polymerase kappa, putative 0.0023 0.0204 0.0745
Loa Loa (eye worm) hypothetical protein 0.0008 0.0025 0.0082
Brugia malayi Serotonin receptor 0.0008 0.0025 0.0082
Echinococcus multilocularis retinol dehydrogenase 11 0.0009 0.0032 0.0032
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0019 0.0148 0.4223
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0011 0.006 0.006
Echinococcus granulosus rhodopsin orphan GPCR 0.0008 0.0025 0.0025
Schistosoma mansoni hypothetical protein 0.0008 0.0025 0.0025
Plasmodium vivax SET domain protein, putative 0.0034 0.0338 1
Loa Loa (eye worm) hypothetical protein 0.0252 0.2988 1
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.0009 0.0032 0.0087
Echinococcus granulosus somatostatin receptor 0.0008 0.0025 0.0025
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0034 0.0338 0.0338
Schistosoma mansoni tar DNA-binding protein 0.0073 0.0805 0.0805
Loa Loa (eye worm) hypothetical protein 0.0008 0.0025 0.0082
Echinococcus granulosus 7tm_1 domain containing protein 0.0008 0.0025 0.0025
Schistosoma mansoni short chain dehydrogenase 0.0009 0.0032 0.0032
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0009 0.0032 0.0159
Mycobacterium ulcerans short chain dehydrogenase 0.0009 0.0032 0.0159
Brugia malayi hypothetical protein 0.0009 0.0032 0.0107
Trypanosoma cruzi hypothetical protein, conserved 0.0009 0.0032 0.0087
Loa Loa (eye worm) hypothetical protein 0.0008 0.0025 0.0082
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0023 0.0204 0.0745
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0009 0.0032 0.0107
Schistosoma mansoni apoferritin-2 0.001 0.004 0.004
Mycobacterium ulcerans short chain dehydrogenase 0.0009 0.0032 0.0159
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0011 0.006 0.1361
Trichomonas vaginalis DNA helicase recq, putative 0.0015 0.0101 0.0215
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0015 0.0101 0.035
Schistosoma mansoni hypothetical protein 0.008 0.0895 0.0895
Mycobacterium ulcerans short chain dehydrogenase 0.0009 0.0032 0.0159
Mycobacterium ulcerans short-chain membrane-associated dehydrogenase 0.0009 0.0032 0.0159
Brugia malayi hypothetical protein 0.0008 0.0025 0.0082
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0037 0.0372 0.0372
Brugia malayi G protein-coupled receptor F59B2.13 0.0008 0.0025 0.0082
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.0009 0.0032 0.0087
Schistosoma mansoni ferritin 0.001 0.004 0.004
Loa Loa (eye worm) hypothetical protein 0.0009 0.0032 0.0108
Entamoeba histolytica phosphofructokinase, putative 0.0124 0.1437 0.5432
Brugia malayi hypothetical protein 0.0008 0.0025 0.0082
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0034 0.0331 0.1234
Loa Loa (eye worm) hypothetical protein 0.0008 0.0025 0.0082
Brugia malayi Dehydrogenases, short chain protein 2 0.0009 0.0032 0.0107
Brugia malayi D-beta-hydroxybutyrate dehydrogenase, mitochondrial precursor 0.0009 0.0032 0.0107
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0015 0.0101 0.035
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0008 0.0025 0.0025
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.0009 0.0032 0.0087
Loa Loa (eye worm) MH1 domain-containing protein 0.0009 0.0035 0.0118
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0009 0.0032 0.0032
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0012 0.007 0.0141
Echinococcus granulosus allatostatin A receptor 0.0008 0.0025 0.0025
Schistosoma mansoni smad1 5 8 and 0.0009 0.0035 0.0035
Mycobacterium ulcerans short-chain type oxidoreductase 0.0009 0.0032 0.0159
Brugia malayi Latrophilin receptor protein 2 0.0037 0.0372 0.124
Echinococcus granulosus neuropeptide receptor A26 0.056 0.6743 0.6743
Brugia malayi Melatonin receptor type 1A 0.0008 0.0025 0.0082
Onchocerca volvulus 0.0009 0.0032 0.0024
Echinococcus granulosus neuropeptide FF receptor 2 0.0008 0.0025 0.0025
Plasmodium vivax steroid dehydrogenase, putative 0.0009 0.0032 0.0692
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0008 0.0025 0.0025
Echinococcus multilocularis rhodopsin orphan GPCR 0.0008 0.0025 0.0025
Echinococcus multilocularis oxidoreductase 0.0009 0.0032 0.0032
Echinococcus granulosus orexin receptor type 2 0.0008 0.0025 0.0025
Onchocerca volvulus 0.0009 0.0032 0.0024
Echinococcus granulosus Smad4 0.0009 0.0035 0.0035
Leishmania major oxidoreductase-like protein 0.0009 0.0032 0.0087
Loa Loa (eye worm) G-protein coupled receptor 0.0008 0.0025 0.0082
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0204 0.0745
Loa Loa (eye worm) hypothetical protein 0.0009 0.0032 0.0108
Schistosoma mansoni amine GPCR 0.0008 0.0025 0.0025
Mycobacterium ulcerans short-chain dehydrogenase 0.0009 0.0032 0.0159
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0012 0.007 0.0233
Loa Loa (eye worm) hypothetical protein 0.0008 0.0025 0.0082
Loa Loa (eye worm) 6-phosphofructokinase 0.0124 0.1437 0.4809
Loa Loa (eye worm) hypothetical protein 0.0034 0.0338 0.1131
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0009 0.0032 0.0107
Trypanosoma brucei DNA polymerase IV, putative 0.0023 0.0204 0.0745
Mycobacterium tuberculosis Bacterioferritin BfrB 0.001 0.004 0.0056
Brugia malayi dehydrogenases, short chain protein 2 0.0009 0.0032 0.0107
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0008 0.0025 0.0025
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0124 0.1437 1
Plasmodium vivax hypothetical protein, conserved 0.0009 0.0032 0.0692
Brugia malayi Hypothetical oxidoreductase F56D1.5 0.0009 0.0032 0.0107
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0008 0.0025 0.0025
Schistosoma mansoni kinase 0.0113 0.1292 0.1292
Leishmania major quinonoid dihydropteridine reductase 0.0009 0.0032 0.0087
Onchocerca volvulus 0.0009 0.0032 0.0024
Echinococcus multilocularis thyroid hormone receptor alpha 0.0012 0.007 0.007
Schistosoma mansoni hypothetical protein 0.0037 0.0372 0.0372
Schistosoma mansoni tar DNA-binding protein 0.0073 0.0805 0.0805
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0012 0.007 0.007
Toxoplasma gondii 6-phosphofructokinase 0.0034 0.0331 0.8649
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0009 0.0032 0.0611
Schistosoma mansoni ferritin light chain 0.001 0.004 0.004
Brugia malayi RE15519p 0.0008 0.0025 0.0082
Mycobacterium ulcerans short-chain dehydrogenase 0.0009 0.0032 0.0159
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0009 0.0032 0.0107
Schistosoma mansoni adenoreceptor 0.0008 0.0025 0.0025
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0012 0.007 0.007
Echinococcus multilocularis carbonyl reductase 1 0.0009 0.0032 0.0032
Echinococcus multilocularis epidermal retinal dehydrogenase 2 0.0009 0.0032 0.0032
Trypanosoma brucei DNA polymerase IV, putative 0.0023 0.0204 0.0745
Trypanosoma cruzi polo-like protein kinase, putative 0.0221 0.2618 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0008 0.0025 0.0025
Echinococcus granulosus Dehydrogenase:reductase SDR family 0.0009 0.0032 0.0032
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0012 0.007 0.0233
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0124 0.1437 0.5472
Schistosoma mansoni steroid dehydrogenase 0.0009 0.0032 0.0032
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0124 0.1437 1
Echinococcus multilocularis fmrfamide receptor 0.0008 0.0025 0.0025
Brugia malayi ImpB/MucB/SamB family protein 0.0054 0.0576 0.1918
Brugia malayi hypothetical protein 0.0008 0.0025 0.0082
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0012 0.007 0.0232
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0011 0.006 0.1361
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0012 0.007 0.0233
Echinococcus multilocularis serotonin receptor 0.0008 0.0025 0.0025
Loa Loa (eye worm) RNA binding protein 0.0073 0.0805 0.2694
Loa Loa (eye worm) melatonin receptor type 1A 0.0008 0.0025 0.0082
Echinococcus granulosus dro:myosuppressin receptor 0.0008 0.0025 0.0025
Echinococcus granulosus bloom syndrome protein 0.0027 0.0257 0.0257
Trypanosoma brucei unspecified product 0.0016 0.0116 0.041
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0008 0.0025 0.0025
Mycobacterium ulcerans short chain dehydrogenase 0.0009 0.0032 0.0159
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0009 0.0032 0.0159
Echinococcus multilocularis carbonyl reductase 1 0.0009 0.0032 0.0032
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0012 0.007 0.007
Brugia malayi TAR-binding protein 0.0073 0.0805 0.268
Echinococcus granulosus carbonyl reductase 1 0.0009 0.0032 0.0032
Schistosoma mansoni Smad4 0.0009 0.0035 0.0035
Entamoeba histolytica phosphofructokinase, putative 0.0124 0.1437 0.5432
Mycobacterium ulcerans dehydrogenase/reductase 0.0009 0.0032 0.0159
Trypanosoma cruzi short chain dehydrogenase, putative 0.0009 0.0032 0.0087
Loa Loa (eye worm) hypothetical protein 0.0008 0.0025 0.0082
Brugia malayi RNA recognition motif domain containing protein 0.0073 0.0805 0.268
Toxoplasma gondii sterol carrier protein-2 HAD-2SCP-2 0.0009 0.0032 0.0611
Brugia malayi RNA binding protein 0.0073 0.0805 0.268
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0008 0.0025 0.0025
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0008 0.0025 0.0025
Schistosoma mansoni biogenic amine receptor 0.0008 0.0025 0.0025
Trypanosoma cruzi hypothetical protein, conserved 0.0009 0.0032 0.0087
Echinococcus granulosus g-protein coupled receptor 0.0008 0.0025 0.0025
Mycobacterium ulcerans dehydrogenase 0.0009 0.0032 0.0159
Echinococcus granulosus rhodopsin orphan GPCR 0.0008 0.0025 0.0025
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0023 0.0204 0.0204
Echinococcus multilocularis neuropeptide Y receptor 0.0008 0.0025 0.0025
Trichomonas vaginalis DNA helicase recq, putative 0.0027 0.0257 0.0703
Trichomonas vaginalis phosphofructokinase, putative 0.0034 0.0331 0.0937
Echinococcus granulosus g protein coupled receptor 0.0008 0.0025 0.0025
Leishmania major quinonoid dihydropteridine reductase 0.0009 0.0032 0.0087
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0009 0.0032 0.0107
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0011 0.006 0.02
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0011 0.006 0.006
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0023 0.0204 0.0538
Onchocerca volvulus 0.0009 0.0032 0.0024
Schistosoma mansoni hypothetical protein 0.0008 0.0025 0.0025
Echinococcus multilocularis Dehydrogenase:reductase SDR family 0.0009 0.0032 0.0032
Echinococcus granulosus 7TM GPCR rhodopsin 0.0008 0.0025 0.0025
Echinococcus multilocularis steroid dehydrogenase 0.0009 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0008 0.0025 0.0082
Schistosoma mansoni short chain dehydrogenase 0.0009 0.0032 0.0032
Trichomonas vaginalis CAMK family protein kinase 0.0221 0.2618 0.8103
Schistosoma mansoni short-chain dehydrogenase/reductase 0.0009 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0008 0.0025 0.0082
Echinococcus multilocularis 6 phosphofructokinase 0.0124 0.1437 0.1437
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.0338 0.0338
Trypanosoma cruzi hypothetical protein, conserved 0.0009 0.0032 0.0087
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0012 0.007 0.007
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0008 0.0025 0.0025
Schistosoma mansoni steroid dehydrogenase 0.0009 0.0032 0.0032
Trichomonas vaginalis DNA polymerase eta, putative 0.0023 0.0204 0.0538
Echinococcus multilocularis tar DNA binding protein 0.0073 0.0805 0.0805
Echinococcus granulosus 6 phosphofructokinase 0.0124 0.1437 0.1437
Mycobacterium ulcerans short chain dehydrogenase 0.0009 0.0032 0.0159
Echinococcus multilocularis FTZ F1 alpha 0.0012 0.007 0.007
Trypanosoma cruzi DNA polymerase eta, putative 0.0038 0.0382 0.1426
Schistosoma mansoni 6-phosphofructokinase 0.0124 0.1437 0.1437
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0204 0.0745
Brugia malayi nuclear hormone receptor 0.0012 0.007 0.0232
Schistosoma mansoni steroid dehydrogenase 0.0009 0.0032 0.0032
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0037 0.0372 0.0372
Loa Loa (eye worm) hypothetical protein 0.0138 0.1606 0.5375
Mycobacterium ulcerans bacterioferritin BfrB 0.001 0.004 0.0215
Schistosoma mansoni short chain dehydrogenase 0.0009 0.0032 0.0032
Brugia malayi Helix-loop-helix DNA-binding domain containing protein 0.0253 0.3003 1
Mycobacterium ulcerans short chain dehydrogenase 0.0009 0.0032 0.0159
Trypanosoma brucei 3-keto-dihydrosphingosine reductase 0.0009 0.0032 0.0087
Loa Loa (eye worm) helix-loop-helix DNA-binding domain-containing protein 0.0252 0.2988 1
Brugia malayi G protein-coupled receptor 0.0008 0.0025 0.0082
Leishmania major DNA polymerase eta, putative 0.0054 0.0576 0.2171
Echinococcus granulosus tar DNA binding protein 0.0073 0.0805 0.0805
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0012 0.007 0.0233
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0009 0.0032 0.0032
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0008 0.0025 0.0082
Entamoeba histolytica phosphofructokinase, putative 0.0124 0.1437 0.5432
Loa Loa (eye worm) hypothetical protein 0.0008 0.0025 0.0082
Loa Loa (eye worm) dehydrogenase 0.0009 0.0032 0.0108
Echinococcus multilocularis rhodopsin orphan GPCR 0.0008 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0008 0.0025 0.0082
Leishmania major quinonoid dihydropteridine reductase 0.0009 0.0032 0.0087
Loa Loa (eye worm) Smad1 0.0009 0.0035 0.0118
Echinococcus granulosus serotonin receptor 0.0008 0.0025 0.0025
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0034 0.0331 0.0937
Echinococcus granulosus neuropeptide receptor 0.0008 0.0025 0.0025
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0008 0.0025 0.0025
Schistosoma mansoni DNA polymerase IV / kappa 0.0007 0.001 0.001
Schistosoma mansoni tar DNA-binding protein 0.0073 0.0805 0.0805
Schistosoma mansoni RAR-like nuclear receptor 0.0012 0.007 0.007
Trichomonas vaginalis CAMK family protein kinase 0.011 0.1257 0.3837
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0008 0.0025 0.0025
Loa Loa (eye worm) oxidoreductase 0.0009 0.0032 0.0108
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0008 0.0025 0.0025
Echinococcus multilocularis expressed protein 0.001 0.004 0.004
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0012 0.007 0.007
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0008 0.0025 0.0025
Schistosoma mansoni tar DNA-binding protein 0.0073 0.0805 0.0805
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0073 0.0805 0.2694
Schistosoma mansoni amine GPCR 0.0008 0.0025 0.0025
Echinococcus granulosus neuropeptide Y receptor 0.0008 0.0025 0.0025
Brugia malayi Dopamine receptor protein 1 0.0008 0.0025 0.0082
Schistosoma mansoni short chain dehydrogenase 0.0009 0.0032 0.0032
Schistosoma mansoni retinal dehydrogenase 0.0009 0.0032 0.0032
Giardia lamblia DINP protein human, muc B family 0.0023 0.0204 0.0745
Echinococcus granulosus alpha 1A adrenergic receptor 0.0008 0.0025 0.0025
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0034 0.0331 0.5
Echinococcus multilocularis neuropeptide receptor 0.0008 0.0025 0.0025
Echinococcus multilocularis ferritin 0.001 0.004 0.004
Loa Loa (eye worm) hypothetical protein 0.0012 0.007 0.0233
Trypanosoma brucei polo-like protein kinase 0.0221 0.2618 1
Schistosoma mansoni blooms syndrome DNA helicase 0.0022 0.0186 0.0186
Leishmania major hypothetical protein, conserved 0.0009 0.0032 0.0087
Schistosoma mansoni histamine h1 receptor 0.0008 0.0025 0.0025
Schistosoma mansoni retinoic acid receptor RXR 0.0012 0.007 0.007
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0124 0.1437 0.5472
Loa Loa (eye worm) MH2 domain-containing protein 0.0009 0.0035 0.0118
Echinococcus granulosus smad 0.0009 0.0035 0.0035
Loa Loa (eye worm) oxidoreductase 0.0009 0.0032 0.0108
Trypanosoma brucei short-chain dehydrogenase, putative 0.0009 0.0032 0.0087
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0009 0.0032 0.0159
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0037 0.0372 0.0372
Echinococcus multilocularis neuropeptides capa receptor 0.0008 0.0025 0.0025
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0012 0.007 0.007
Giardia lamblia Hypothetical protein 0.0009 0.0032 0.0087
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0009 0.0032 0.0107
Leishmania major short chain dehydrogenase/reductase, putative 0.0009 0.0032 0.0087
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0038 0.0382 1
Schistosoma mansoni opsin-like receptor 0.0008 0.0025 0.0025
Brugia malayi 6-phosphofructokinase 0.0124 0.1437 0.4785
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0024 0.0216 0.6416
Echinococcus granulosus dna polymerase kappa 0.0023 0.0204 0.0204
Echinococcus multilocularis sex peptide receptor 0.0008 0.0025 0.0025
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0009 0.0032 0.0107
Echinococcus granulosus WW domain containing oxidoreductase 0.0009 0.0032 0.0032
Brugia malayi hypothetical protein 0.0008 0.0025 0.0082
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0008 0.0025 0.0025
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0012 0.007 0.007
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0008 0.0025 0.0082
Loa Loa (eye worm) hypothetical protein 0.0012 0.007 0.0233
Echinococcus multilocularis allatostatin A receptor 0.0008 0.0025 0.0025
Schistosoma mansoni steroid dehydrogenase 0.0009 0.0032 0.0032
Trichomonas vaginalis CAMK family protein kinase 0.0221 0.2618 0.8103
Echinococcus granulosus retinol dehydrogenase 11 0.0009 0.0032 0.0032
Trichomonas vaginalis phosphofructokinase, putative 0.0124 0.1437 0.4402
Schistosoma mansoni short chain dehydrogenase 0.0009 0.0032 0.0032
Schistosoma mansoni short chain dehydrogenase 0.0009 0.0032 0.0032
Echinococcus granulosus transcription factor eb 0.0253 0.3003 0.3003
Brugia malayi ecdysteroid receptor 0.0012 0.007 0.0232
Schistosoma mansoni short chain dehydrogenase 0.0009 0.0032 0.0032
Onchocerca volvulus 0.0009 0.0032 0.0024
Loa Loa (eye worm) oxidoreductase 0.0009 0.0032 0.0108
Echinococcus multilocularis GPCR, family 2 0.0037 0.0372 0.0372
Trichomonas vaginalis phosphofructokinase, putative 0.0034 0.0331 0.0937
Schistosoma mansoni DNA helicase recq5 0.0011 0.006 0.006

Activities

Activity type Activity value Assay description Source Reference
Inhibition (functional) = 50 % Activity expressed as percent inhibition of anti-TNP IgM level in TNP-LPS immunized mice, at a dose of 10 mg/kg perorally ChEMBL. 12161149
Inhibition (functional) = 50 % Activity expressed as percent inhibition of anti-TNP IgM level in TNP-LPS immunized mice, at a dose of 10 mg/kg perorally ChEMBL. 12161149

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

No external resources registered for this compound

Bibliographic References

1 literature reference was collected for this gene.

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