Detailed information for compound 134372

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 296.274 | Formula: C17H12O5
  • H donors: 2 H acceptors: 4 LogP: 2.76 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1ccc2c(c1)C(=O)/C(=C/c1ccc(c(c1)O)O)/C2=O
  • InChi: 1S/C17H12O5/c1-22-10-3-4-11-12(8-10)17(21)13(16(11)20)6-9-2-5-14(18)15(19)7-9/h2-8,18-19H,1H3/b13-6+
  • InChiKey: PJNBHUBAMHJBSH-AWNIVKPZSA-N  

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens LCK proto-oncogene, Src family tyrosine kinase Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0016 0.0036 0.0036
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0013 0.0015 0.0015
Echinococcus multilocularis ecdysone induced protein 78C 0.0013 0.0015 0.0015
Schistosoma mansoni neuropeptide receptor 0.0027 0.0112 0.0112
Leishmania major protein kinase, putative 0.0032 0.0148 0.0148
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.0108 0.0108
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0112
Echinococcus granulosus PHD finger protein rhinoceros 0.0021 0.007 0.007
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0026 0.0107 0.0667
Schistosoma mansoni serine/threonine protein kinase 0.0032 0.0148 0.0148
Toxoplasma gondii phosphofructokinase PFKII 0.0021 0.0071 0.0071
Schistosoma mansoni inositol transporter 0.0043 0.0219 0.0219
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0027 0.0112 0.0112
Brugia malayi Tachykinin-like peptides receptor 99D 0.0027 0.0112 0.0112
Trichomonas vaginalis guanylate cyclase, putative 0.0023 0.008 0.0457
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.016 0.1028 0.1028
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0112
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.0032 0.0148 0.0148
Trypanosoma brucei cAMP response protein 1, putative 0.0032 0.0148 0.0148
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0023 0.008 0.0457
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0112
Loa Loa (eye worm) hypothetical protein 0.0016 0.0036 0.0036
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.0032 0.0148 0.0148
Schistosoma mansoni patched 1 0.0036 0.0175 0.0175
Trypanosoma cruzi cAMP response protein 1 0.0032 0.0148 0.0148
Echinococcus granulosus hyperpolarization activated cyclic 0.0049 0.026 0.026
Echinococcus granulosus sodium leak channel non selective protein 0.0016 0.0036 0.0036
Leishmania major hypothetical protein, unknown function 0.0032 0.0148 0.0148
Echinococcus granulosus transient receptor potential cation channel 0.0016 0.0036 0.0036
Brugia malayi Voltage-gated calcium channel, P/Q-type, alpha subunit. C. elegans unc-2 ortholog 0.0016 0.0036 0.0036
Echinococcus multilocularis g protein coupled receptor 0.0027 0.0112 0.0112
Schistosoma mansoni hypothetical protein 0.0187 0.1219 0.1219
Echinococcus granulosus hexokinase type 2 0.1457 1 1
Echinococcus multilocularis potassium voltage gated channel subfamily A 0.0016 0.0036 0.0036
Schistosoma mansoni two-pore calcium channel 0.0016 0.0036 0.0036
Echinococcus multilocularis expressed conserved protein 0.0079 0.0473 0.0473
Onchocerca volvulus 0.0027 0.0112 0.0112
Echinococcus multilocularis rhodopsin orphan GPCR 0.0027 0.0112 0.0112
Echinococcus granulosus FTZ F1 alpha 0.0013 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0016 0.0036 0.0036
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0016 0.0036 0.0036
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0016 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0013 0.0015 0.0015
Trichomonas vaginalis phosphofructokinase, putative 0.0021 0.0071 0.0404
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0048 0.0258 0.0258
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0027 0.0112 0.0112
Echinococcus granulosus voltage dependent calcium channel 0.0016 0.0036 0.0036
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0016 0.0036 0.0036
Echinococcus granulosus jumonji domain containing protein 0.0029 0.0127 0.0127
Schistosoma mansoni hypothetical protein 0.0023 0.008 0.008
Trichomonas vaginalis phosphofructokinase, putative 0.0078 0.0467 0.2674
Brugia malayi hexokinase type II 0.0463 0.3128 0.3128
Onchocerca volvulus 0.0036 0.0175 0.0175
Leishmania major regulatory subunit of protein kinase a-like protein 0.0032 0.0148 0.0148
Echinococcus multilocularis Niemann Pick C1 protein 0.0084 0.0509 0.0509
Schistosoma mansoni camp-dependent protein kinase type I-beta regulatory subunit 0.0032 0.0148 0.0148
Schistosoma mansoni cyclic nucleotide-gated ion channel 0.0032 0.0148 0.0148
Brugia malayi Fli-1 protein 0.0215 0.1409 0.1409
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0048 0.0258 0.0258
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0048 0.0258 0.0258
Schistosoma mansoni hypothetical protein 0.0035 0.0166 0.0166
Trypanosoma brucei importin beta-1 subunit, putative 0.0018 0.0045 0.0045
Trypanosoma brucei PAB1-binding protein , putative 0.0027 0.0108 0.0108
Onchocerca volvulus 0.0092 0.0562 0.0562
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0032 0.0148 0.0148
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.0108 0.0108
Loa Loa (eye worm) hypothetical protein 0.0038 0.0187 0.0187
Trypanosoma cruzi inositol 1,4,5-trisphosphate receptor, putative 0.0016 0.0036 0.0036
Trichomonas vaginalis adenylate cyclase type IX, putative 0.0023 0.008 0.0457
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0229 0.151 0.8648
Echinococcus multilocularis allatostatin A receptor 0.0027 0.0112 0.0112
Brugia malayi hypothetical protein 0.104 0.7118 0.7118
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0026 0.0107 0.0667
Schistosoma mansoni alpha-glucosidase 0.0137 0.0874 0.0874
Echinococcus granulosus voltage gated hydrogen channel 1 0.0016 0.0036 0.0036
Mycobacterium ulcerans hypothetical protein 0.0032 0.0148 0.3172
Brugia malayi Bromodomain containing protein 0.0024 0.0087 0.0087
Echinococcus granulosus g protein coupled receptor 0.0027 0.0112 0.0112
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.0032 0.0148 0.0148
Loa Loa (eye worm) hypothetical protein 0.0013 0.0015 0.0015
Onchocerca volvulus 0.0027 0.0112 0.0112
Echinococcus multilocularis high affinity choline transporter 1 0.0387 0.2598 0.2598
Mycobacterium leprae Possible transporter protein 0.0023 0.008 0.171
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0027 0.0112 0.0112
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0027 0.0112 0.0112
Echinococcus multilocularis somatostatin receptor 0.0027 0.0112 0.0112
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.003 0.0131 0.0131
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0027 0.0112 0.0112
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0013 0.0013 0.0013
Brugia malayi cytoplasmic intermediate filament protein 0.0019 0.0059 0.0059
Echinococcus multilocularis expressed conserved protein 0.0032 0.0148 0.0148
Loa Loa (eye worm) beta-lactamase 0.0038 0.0187 0.0187
Brugia malayi Transient-receptor-potential like protein 0.0016 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0013 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0071 0.0416 0.0416
Brugia malayi aryl hydrocarbon receptor nuclear translocator protein, putative 0.0023 0.008 0.008
Trichomonas vaginalis phosphofructokinase, putative 0.0021 0.0071 0.0404
Trichomonas vaginalis guanylate cyclase beta 1 subunit, putative 0.0023 0.008 0.0457
Onchocerca volvulus 0.0027 0.0112 0.0112
Trypanosoma brucei glycosyl hydrolase-like protein 0.0013 0.0015 0.0015
Onchocerca volvulus 0.1457 1 1
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0112
Mycobacterium leprae Conserved hypothetical protein 0.0032 0.0148 0.3172
Schistosoma mansoni voltage-gated potassium channel 0.0016 0.0036 0.0036
Toxoplasma gondii ABC1 family protein 0.0038 0.0187 0.0187
Plasmodium vivax CAMP-dependent protein kinase regulatory subunit, putative 0.0032 0.0148 0.0148
Schistosoma mansoni voltage-gated potassium channel 0.0016 0.0036 0.0036
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0023 0.008 0.0457
Loa Loa (eye worm) hypothetical protein 0.0038 0.0187 0.0187
Treponema pallidum cyclic nucleotide binding protein 0.0032 0.0148 0.0078
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0027 0.0112 0.0112
Onchocerca volvulus 0.0032 0.0148 0.0148
Onchocerca volvulus 0.0038 0.0187 0.0187
Brugia malayi putative neuropeptide receptor NPR1 0.0027 0.0112 0.0112
Echinococcus granulosus microtubule associated protein 2 0.0975 0.6669 0.6669
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0027 0.0112 0.0112
Onchocerca volvulus 0.0027 0.0112 0.0112
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0071 0.0413 0.0413
Echinococcus multilocularis cAMP dependent protein kinase type II regulatory 0.0032 0.0148 0.0148
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.003 0.0131 0.0131
Loa Loa (eye worm) hypothetical protein 0.0036 0.0175 0.0175
Trichomonas vaginalis adenylate cyclase, putative 0.0023 0.008 0.0457
Trichomonas vaginalis phosphofructokinase, putative 0.0078 0.0467 0.2674
Loa Loa (eye worm) hypothetical protein 0.0038 0.0187 0.0187
Loa Loa (eye worm) hypothetical protein 0.0013 0.0015 0.0015
Schistosoma mansoni calcium channel voltage-dependent p/q type alpha 1a-related 0.0016 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0036 0.0175 0.0175
Echinococcus multilocularis transient receptor potential cation channel 0.0016 0.0036 0.0036
Echinococcus multilocularis potassium voltage gated channel protein 0.0016 0.0036 0.0036
Echinococcus multilocularis sodium coupled monocarboxylate transporter 1 0.0043 0.0219 0.0219
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0078 0.0467 0.0467
Echinococcus granulosus hexokinase 0.1457 1 1
Onchocerca volvulus 0.0027 0.0112 0.0112
Chlamydia trachomatis cAMP-dependent protein kinase regulatory subunit 0.0032 0.0148 1
Echinococcus multilocularis hexokinase 0.1457 1 1
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0018 0.0045 0.0045
Schistosoma mansoni camp-dependent protein kinase type I-beta regulatory subunit 0.0032 0.0148 0.0148
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0013 0.0015 0.0015
Toxoplasma gondii hexokinase 0.1457 1 1
Treponema pallidum cyclic nucleotide binding protein 0.0032 0.0148 0.0078
Loa Loa (eye worm) hypothetical protein 0.0028 0.0118 0.0118
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit 0.0016 0.0036 0.0036
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0037 0.0183 0.3922
Loa Loa (eye worm) hypothetical protein 0.0993 0.6796 0.6796
Echinococcus granulosus sodium:glucose cotransporter 2 0.0043 0.0219 0.0219
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0049 0.026 0.026
Loa Loa (eye worm) acetyltransferase 0.0105 0.0648 0.0648
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0245 0.1622 0.1622
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0013 0.0015 0.0015
Brugia malayi GH02984p 0.0387 0.2598 0.2598
Brugia malayi Glycosyl hydrolases family 31 protein 0.016 0.1028 0.1028
Echinococcus granulosus TRP transient receptor potential channel 0.0016 0.0036 0.0036
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0013 0.0015 0.0015
Echinococcus granulosus voltage gated potassium channel 0.0071 0.0416 0.0416
Schistosoma mansoni thyroid hormone receptor 0.0013 0.0015 0.0015
Toxoplasma gondii 6-phosphofructokinase 0.0021 0.0071 0.0071
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.008 0.0457
Trichomonas vaginalis guanylate cyclase, putative 0.0023 0.008 0.0457
Echinococcus granulosus sodium:myo inositol cotransporter 0.0043 0.0219 0.0219
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0245 0.1622 0.1622
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0028 0.0115 0.0115
Plasmodium vivax hypothetical protein, conserved 0.0038 0.0187 0.0187
Schistosoma mansoni intermediate filament proteins 0.0036 0.0175 0.0175
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0013 0.0015 0.0015
Echinococcus granulosus serotonin receptor 0.0027 0.0112 0.0112
Onchocerca volvulus 0.0036 0.0175 0.0175
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0229 0.151 0.8648
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0016 0.0036 0.0036
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0013 0.0015 0.0015
Schistosoma mansoni nuclear hormone receptor 0.0013 0.0015 0.0015
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0027 0.0112 0.0112
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0027 0.0112 0.0112
Trichomonas vaginalis phosphofructokinase, putative 0.0078 0.0467 0.2674
Entamoeba histolytica acetyltransferase, GNAT family 0.0028 0.0119 0.0119
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0112
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0013 0.0015 0.0015
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0027 0.0112 0.0112
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0016 0.0036 0.0036
Leishmania major hypothetical protein, conserved 0.0027 0.0108 0.0108
Echinococcus multilocularis snurportin 1 0.0187 0.1219 0.1219
Echinococcus granulosus dro:myosuppressin receptor 0.0027 0.0112 0.0112
Echinococcus granulosus transient receptor potential gamma protein 0.0016 0.0036 0.0036
Trichomonas vaginalis sucrase-isomaltase, putative 0.0035 0.0169 0.0967
Schistosoma mansoni neuropeptide F-like receptor 0.0027 0.0112 0.0112
Brugia malayi Serotonin receptor 0.0027 0.0112 0.0112
Echinococcus granulosus Niemann Pick C1 protein 0.0084 0.0509 0.0509
Schistosoma mansoni vesicular amine transporter 0.0016 0.0036 0.0036
Loa Loa (eye worm) cAMP-dependent protein kinase regulatory subunit 0.0032 0.0148 0.0148
Loa Loa (eye worm) hypothetical protein 0.0032 0.0148 0.0148
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0016 0.0036 0.0036
Giardia lamblia PHD finger protein 15 0.0021 0.007 0.4177
Toxoplasma gondii transporter, cation channel family protein 0.0016 0.0036 0.0036
Schistosoma mansoni camp-dependent protein kinase regulatory chain 0.0032 0.0148 0.0148
Echinococcus multilocularis hyperpolarization activated cyclic 0.0049 0.026 0.026
Schistosoma mansoni hypothetical protein 0.0019 0.0055 0.0055
Echinococcus granulosus sodium coupled monocarboxylate transporter 1 0.0043 0.0219 0.0219
Echinococcus granulosus sterol regulatory element binding protein 0.0036 0.0175 0.0175
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0013 0.0015 0.0015
Echinococcus granulosus tm gpcr rhodopsin 0.0027 0.0112 0.0112
Loa Loa (eye worm) hypothetical protein 0.006 0.0342 0.0342
Schistosoma mansoni hypothetical protein 0.0016 0.0036 0.0036
Brugia malayi Melatonin receptor type 1A 0.0027 0.0112 0.0112
Echinococcus granulosus biogenic amine 5HT receptor 0.0027 0.0112 0.0112
Trichomonas vaginalis alpha-glucosidase, putative 0.0013 0.0015 0.0087
Onchocerca volvulus 0.0027 0.0112 0.0112
Echinococcus granulosus snurportin 1 0.0187 0.1219 0.1219
Echinococcus granulosus hypothetical protein 0.0016 0.0036 0.0036
Entamoeba histolytica acyl-CoA synthetase, putative 0.0037 0.0183 0.0183
Trichomonas vaginalis alpha-glucosidase, putative 0.0013 0.0015 0.0087
Schistosoma mansoni voltage-dependent calcium channel 0.0016 0.0036 0.0036
Trichomonas vaginalis phosphofructokinase, putative 0.0078 0.0467 0.2674
Brugia malayi hypothetical protein 0.0027 0.0112 0.0112
Trichomonas vaginalis set domain proteins, putative 0.0263 0.1746 1
Brugia malayi hypothetical protein 0.0027 0.0112 0.0112
Loa Loa (eye worm) hexokinase 0.1457 1 1
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0028 0.0118 0.2518
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0187 0.1069
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0187 0.0187
Schistosoma mansoni neuropeptide receptor 0.0027 0.0112 0.0112
Brugia malayi olfactory channel protein osm-9 0.0016 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0016 0.0036 0.0036
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0027 0.0112 0.0112
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0049 0.026 0.026
Plasmodium vivax importin-beta 2, putative 0.0018 0.0045 0.0045
Echinococcus multilocularis neuropeptide Y receptor 0.0027 0.0112 0.0112
Trichomonas vaginalis guanylate cyclase, putative 0.0023 0.008 0.0457
Brugia malayi photoreceptor-specific nuclear receptor 0.0013 0.0015 0.0015
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0016 0.0036 0.0036
Echinococcus granulosus short transient receptor potential channel 6 0.0016 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0018 0.0045 0.0045
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0037 0.0183 0.3922
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0049 0.026 0.1488
Brugia malayi nuclear receptor NHR-88 0.0013 0.0015 0.0015
Echinococcus multilocularis voltage dependent calcium channel 0.0016 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0112
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0048 0.0258 0.0258
Brugia malayi cAMP-dependent protein kinase regulatory chain, putative 0.0032 0.0148 0.0148
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0013 0.0015 0.0015
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0016 0.0036 0.0036
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0018 0.0045 0.0045
Schistosoma mansoni hypothetical protein 0.0035 0.0166 0.0166
Schistosoma mansoni voltage-gated potassium channel 0.0016 0.0036 0.0036
Schistosoma mansoni ap endonuclease 0.003 0.0131 0.0131
Loa Loa (eye worm) neuropeptide F receptor 0.0027 0.0112 0.0112
Echinococcus multilocularis importin subunit beta 1 0.0018 0.0045 0.0045
Schistosoma mansoni voltage-gated potassium channel 0.0016 0.0036 0.0036
Toxoplasma gondii transporter, cation channel family protein 0.0016 0.0036 0.0036
Echinococcus granulosus potassium large conductance calcium activated 0.0016 0.0036 0.0036
Echinococcus multilocularis sodium channel protein 0.0016 0.0036 0.0036
Echinococcus granulosus solute carrier family 5 0.0043 0.0219 0.0219
Brugia malayi AMP-binding enzyme family protein 0.0037 0.0183 0.0183
Loa Loa (eye worm) hypothetical protein 0.0044 0.0231 0.0231
Brugia malayi voltage-dependent calcium channel 0.0016 0.0036 0.0036
Echinococcus granulosus potassium voltage gated channel subfamily C 0.0016 0.0036 0.0036
Echinococcus multilocularis Niemann Pick C1 protein 0.0121 0.0759 0.0759
Schistosoma mansoni amine GPCR 0.0027 0.0112 0.0112
Brugia malayi MH2 domain containing protein 0.0361 0.2418 0.2418
Trichomonas vaginalis alpha-glucosidase, putative 0.0013 0.0015 0.0087
Trichomonas vaginalis esterase, putative 0.0038 0.0187 0.1069
Schistosoma mansoni voltage-gated potassium channel 0.0016 0.0036 0.0036
Plasmodium falciparum importin beta, putative 0.0018 0.0045 0.0045
Brugia malayi hypothetical protein 0.0027 0.0108 0.0108
Echinococcus granulosus potassium channel KvQLT family member kqt 1 0.0016 0.0036 0.0036
Echinococcus granulosus alpha 1A adrenergic receptor 0.0027 0.0112 0.0112
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1281 0.8789 0.8789
Trypanosoma brucei inositol 1,4,5-trisphosphate receptor 0.0016 0.0036 0.0036
Trichomonas vaginalis guanylate cyclase, putative 0.0023 0.008 0.0457
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0049 0.026 0.026
Echinococcus granulosus lamin 0.0036 0.0175 0.0175
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0016 0.0036 0.0036
Echinococcus multilocularis cAMP dependent protein kinase regulatory 0.0032 0.0148 0.0148
Echinococcus granulosus sodium channel protein 0.0016 0.0036 0.0036
Brugia malayi cation channel family protein 0.0016 0.0036 0.0036
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0027 0.0112 0.0112
Echinococcus multilocularis protein dispatched 1 0.0041 0.021 0.021
Echinococcus multilocularis transient receptor potential cation channel 0.0016 0.0036 0.0036
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0033 0.0154 0.0154
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0025 0.0094 0.0094
Brugia malayi beta-lactamase family protein 0.0038 0.0187 0.0187
Echinococcus granulosus histone acetyltransferase KAT2B 0.0102 0.0628 0.0628
Schistosoma mansoni voltage-gated potassium channel 0.0268 0.1778 0.1778
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0187 0.1219 0.1219
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0013 0.0013 0.0013
Schistosoma mansoni sodium/solute symporter 0.0043 0.0219 0.0219
Loa Loa (eye worm) hypothetical protein 0.0036 0.0174 0.0174
Schistosoma mansoni serine/threonine protein kinase 0.0032 0.0148 0.0148
Trichomonas vaginalis adenylate cyclase type vIII, putative 0.0023 0.008 0.0457
Schistosoma mansoni biogenic amine (5HT) receptor 0.0027 0.0112 0.0112
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0016 0.0036 0.0036
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0021 0.0071 0.4255
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0013 0.0015 0.0015
Plasmodium falciparum histone acetyltransferase GCN5 0.0028 0.0119 0.0119
Echinococcus granulosus potassium voltage gated channel protein 0.0016 0.0036 0.0036
Leishmania major hypothetical protein, conserved 0.0032 0.0148 0.0148
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.003 0.0131 0.0131
Loa Loa (eye worm) calcium channel 0.0016 0.0036 0.0036
Schistosoma mansoni hypothetical protein 0.0032 0.0148 0.0148
Loa Loa (eye worm) hypothetical protein 0.0074 0.0436 0.0436
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0112
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0049 0.026 0.026
Echinococcus granulosus calcium activated potassium channel 0.0016 0.0036 0.0036
Trypanosoma brucei STE group serine/threonine-protein kinase, putative 0.0023 0.008 0.008
Schistosoma mansoni smad 0.0025 0.0094 0.0094
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.008 0.0457
Trichomonas vaginalis adenylyl cyclase type V, putative 0.0023 0.008 0.0457
Trypanosoma cruzi hypothetical protein, conserved 0.0032 0.0148 0.0148
Trichomonas vaginalis adenylate cyclase type, putative 0.0023 0.008 0.0457
Echinococcus granulosus lysosomal alpha glucosidase 0.016 0.1028 0.1028
Schistosoma mansoni neuropeptide F-like receptor 0.0027 0.0112 0.0112
Schistosoma mansoni hypothetical protein 0.0212 0.1391 0.1391
Trichomonas vaginalis adenylate cyclase, putative 0.0023 0.008 0.0457
Schistosoma mansoni jumonji/arid domain-containing protein 0.0025 0.01 0.01
Leishmania major GTP-binding protein, putative 0.0013 0.0013 0.0013
Schistosoma mansoni ran 0.0013 0.0013 0.0013
Loa Loa (eye worm) Smad1 0.0025 0.0094 0.0094
Onchocerca volvulus Protein ultraspiracle homolog 0.0013 0.0015 0.0015
Echinococcus granulosus neutral alpha glucosidase AB 0.0035 0.0169 0.0169
Onchocerca volvulus 0.0033 0.0154 0.0154
Trichomonas vaginalis guanylate cyclase beta 2 subunit, putative 0.0023 0.008 0.0457
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0019 0.0059 0.0059
Schistosoma mansoni neuropathy target esterase/swiss cheese-related protein 0.0032 0.0148 0.0148
Entamoeba histolytica hypothetical protein 0.0083 0.0495 0.0495
Onchocerca volvulus Hexokinase homolog 0.0914 0.6245 0.6245
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0027 0.0112 0.0112
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0187 0.1069
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0078 0.0467 1
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0032 0.0148 0.0848
Schistosoma mansoni alpha-glucosidase 0.0137 0.0874 0.0874
Leishmania major importin beta-1 subunit, putative 0.0014 0.0022 0.0022
Onchocerca volvulus Neuropeptide F receptor homolog 0.0027 0.0112 0.0112
Trichomonas vaginalis maltase-glucoamylase, putative 0.0035 0.0169 0.0967
Loa Loa (eye worm) MH2 domain-containing protein 0.0025 0.0094 0.0094
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0023 0.008 0.0457
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0013 0.0015 0.0015
Mycobacterium tuberculosis Conserved hypothetical protein 0.0032 0.0148 0.0924
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0013 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0112
Entamoeba histolytica phosphofructokinase, putative 0.0078 0.0467 0.0467
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0032 0.0148 0.0148
Echinococcus granulosus voltage gated potassium channel 0.0016 0.0036 0.0036
Echinococcus multilocularis neuropeptide Y receptor 0.0027 0.0112 0.0112
Loa Loa (eye worm) 6-phosphofructokinase 0.0078 0.0467 0.0467
Trichomonas vaginalis intestinal guanylate cyclase, putative 0.0023 0.008 0.0457
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0016 0.0036 0.0036
Brugia malayi RE15519p 0.0027 0.0112 0.0112
Brugia malayi jmjC domain containing protein 0.0069 0.0401 0.0401
Schistosoma mansoni gabp alpha 0.0071 0.0413 0.0413
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0048 0.0258 0.0258
Mycobacterium tuberculosis Conserved protein 0.0038 0.0187 0.1165
Loa Loa (eye worm) hypothetical protein 0.0017 0.0041 0.0041
Echinococcus granulosus cGMP dependent protein kinase 1 0.0032 0.0148 0.0148
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.003 0.0131 0.0131
Trypanosoma brucei protein kinase A regulatory subunit 0.0032 0.0148 0.0148
Schistosoma mansoni camp-dependent protein kinase type II regulatory subunit 0.0032 0.0148 0.0148
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0175 0.1001
Mycobacterium tuberculosis Probable esterase LipL 0.0038 0.0187 0.1165
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0038 0.0187 0.3999
Echinococcus granulosus transient receptor potential cation channel 0.0016 0.0036 0.0036
Brugia malayi Large-conductance calcium-activated potassium channel Slo-1 (KCNMA) alpha subunit. C. elegans slo-1 ortholog 0.0016 0.0036 0.0036
Mycobacterium ulcerans hypothetical protein 0.0032 0.0148 0.3172
Mycobacterium tuberculosis Probable conserved transmembrane protein 0.0032 0.0148 0.0924
Echinococcus multilocularis potassium voltage gated channel subfamily KQT 0.0016 0.0036 0.0036
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0027 0.0112 0.0112
Onchocerca volvulus 0.0027 0.0112 0.0112
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0112
Echinococcus granulosus GTP binding nuclear protein Ran 0.0013 0.0013 0.0013
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0023 0.008 0.0457
Brugia malayi ion channel NompC 0.0016 0.0036 0.0036
Trichomonas vaginalis guanylate cyclase, putative 0.0023 0.008 0.0457
Echinococcus granulosus neuropeptide receptor 0.0027 0.0112 0.0112
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0021 0.0071 0.0404
Schistosoma mansoni amine GPCR 0.0027 0.0112 0.0112
Trichomonas vaginalis ran, putative 0.0013 0.0013 0.0075
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0027 0.0112 0.0112
Trichomonas vaginalis adenylate cyclase type IX, putative 0.0023 0.008 0.0457
Trichomonas vaginalis adenylate cyclase type VI, putative 0.0023 0.008 0.0457
Brugia malayi jmjC domain containing protein 0.0025 0.01 0.01
Echinococcus granulosus GA binding protein alpha chain 0.0071 0.0413 0.0413
Loa Loa (eye worm) hypothetical protein 0.0014 0.0018 0.0018
Trichomonas vaginalis cAMP-dependent protein kinase regulatory subunit, putative 0.0032 0.0148 0.0848
Schistosoma mansoni inositol 145-trisphosphate receptor 0.0016 0.0036 0.0036
Brugia malayi Calcitonin receptor-like protein seb-1 0.0028 0.0115 0.0115
Loa Loa (eye worm) hypothetical protein 0.0028 0.0118 0.0118
Plasmodium vivax 6-phosphofructokinase, putative 0.0021 0.0071 0.0071
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0112
Brugia malayi neuropeptide F receptor 0.0027 0.0112 0.0112
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0031 0.0137 0.0137
Trichomonas vaginalis phosphofructokinase, putative 0.0021 0.0071 0.0404
Echinococcus multilocularis rhodopsin orphan GPCR 0.0027 0.0112 0.0112
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0023 0.008 0.0457
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0112
Brugia malayi Pre-SET motif family protein 0.0033 0.0154 0.0154
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0023 0.008 0.0457
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0049 0.026 0.026
Brugia malayi beta-lactamase 0.0038 0.0187 0.0187
Entamoeba histolytica hexokinase 1 0.1457 1 1
Brugia malayi hypothetical protein 0.0027 0.0112 0.0112
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.0258 0.0258
Schistosoma mansoni biogenic amine receptor 0.0027 0.0112 0.0112
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0027 0.0112 0.0112
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0016 0.0036 0.0036
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0027 0.0112 0.0112
Brugia malayi AKH receptor 0.0027 0.0112 0.0112
Schistosoma mansoni hypothetical protein 0.0103 0.0637 0.0637
Mycobacterium tuberculosis Probable glutamine-transport ATP-binding protein ABC transporter GlnQ 0.0032 0.0148 0.0924
Plasmodium vivax ataxin-2 like protein, putative 0.0027 0.0108 0.0108
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0014 0.0022 0.0127
Echinococcus multilocularis g-protein coupled receptor 0.0027 0.0112 0.0112
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0169 0.0967
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0032 0.0148 0.0848
Echinococcus multilocularis neuropeptide FF receptor 2 0.0027 0.0112 0.0112
Echinococcus granulosus histone acetyltransferase KAT2B 0.0031 0.0137 0.0137
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.008 0.0457
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0032 0.0145 0.0145
Trichomonas vaginalis adenylate cyclase, putative 0.0023 0.008 0.0457
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0112
Entamoeba histolytica exodeoxyribonuclease III, putative 0.003 0.0131 0.0131
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.003 0.0131 0.0131
Loa Loa (eye worm) hypothetical protein 0.0036 0.0171 0.0171
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0027 0.0112 0.0112
Schistosoma mansoni alpha glucosidase 0.0035 0.0169 0.0169
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0027 0.0112 0.0112
Trichomonas vaginalis ap endonuclease, putative 0.003 0.0131 0.0749
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0112
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.003 0.0131 0.5
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0069 0.0401 0.0401
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit. C. elegans exp-2 ortholog 0.0016 0.0036 0.0036
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0027 0.0112 0.0112
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0027 0.0112 0.0112
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0027 0.0112 0.0112
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.003 0.0131 0.0816
Onchocerca volvulus 0.0027 0.0112 0.0112
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0049 0.026 0.026
Onchocerca volvulus 0.0027 0.0112 0.0112
Treponema pallidum exodeoxyribonuclease (exoA) 0.003 0.0131 0.0061
Brugia malayi hypothetical protein 0.0027 0.0112 0.0112
Brugia malayi Hexokinase family protein 0.0451 0.3042 0.3042
Brugia malayi acetyltransferase, GNAT family protein 0.0105 0.0648 0.0648
Leishmania major alpha glucosidase II subunit, putative 0.0035 0.0169 0.0169
Echinococcus granulosus rhodopsin orphan GPCR 0.0027 0.0112 0.0112
Leishmania major ATP-dependent phosphofructokinase 0.0078 0.0467 0.0467
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0071 0.0416 0.0416
Schistosoma mansoni jumonji/arid domain-containing protein 0.0025 0.01 0.01
Echinococcus multilocularis neuropeptide receptor 0.0027 0.0112 0.0112
Schistosoma mansoni camp-dependent protein kinase type II-alpha regulatory subunit 0.0032 0.0148 0.0148
Echinococcus multilocularis serotonin receptor 0.0027 0.0112 0.0112
Trichomonas vaginalis guanylate cyclase, putative 0.0023 0.008 0.0457
Trichomonas vaginalis guanylate cyclase, putative 0.0023 0.008 0.0457
Trypanosoma brucei hexokinase 0.1457 1 1
Echinococcus granulosus peregrin 0.0024 0.0087 0.0087
Echinococcus granulosus TGF beta signal transducer SmadC 0.0025 0.0094 0.0094
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0016 0.0036 0.0036
Trypanosoma cruzi protein kinase A regulatory subunit 0.0032 0.0148 0.0148
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0084 0.0509 0.0508
Schistosoma mansoni lamin 0.0036 0.0175 0.0175
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0013 0.0015 0.0015
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0013 0.0013 0.0013
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0013 0.0015 0.0015
Schistosoma mansoni ryanodine receptor related 0.0016 0.0036 0.0036
Echinococcus granulosus G protein coupled receptor 139 0.0027 0.0112 0.0112
Loa Loa (eye worm) hypothetical protein 0.0032 0.0148 0.0148
Echinococcus granulosus rhodopsin orphan GPCR 0.0027 0.0112 0.0112
Schistosoma mansoni voltage-gated potassium channel 0.0016 0.0036 0.0036
Trichomonas vaginalis adenylate cyclase type IX, putative 0.0023 0.008 0.0457
Echinococcus granulosus lysine specific demethylase 5A 0.0025 0.01 0.01
Brugia malayi hypothetical protein 0.0074 0.0436 0.0436
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0048 0.0258 0.0258
Echinococcus granulosus two pore calcium channel protein 2 0.0016 0.0036 0.0036
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0016 0.0036 0.0036
Echinococcus granulosus g-protein coupled receptor 0.0027 0.0112 0.0112
Trypanosoma brucei hypothetical protein, conserved 0.0038 0.0187 0.0187
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.0108 0.0108
Echinococcus multilocularis neuropeptide receptor 0.0027 0.0112 0.0112
Schistosoma mansoni microtubule-associated protein tau 0.0975 0.6669 0.6669
Trichomonas vaginalis adenylate cyclase type III, putative 0.0023 0.008 0.0457
Trichomonas vaginalis bromodomain-containing protein, putative 0.0031 0.0137 0.0784
Echinococcus multilocularis Smad4 0.0025 0.0094 0.0094
Loa Loa (eye worm) hypothetical protein 0.0013 0.0015 0.0015
Brugia malayi beta-lactamase family protein 0.0038 0.0187 0.0187
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0013 0.0015 0.0015
Echinococcus multilocularis transient receptor potential gamma protein 0.0016 0.0036 0.0036
Mycobacterium ulcerans acyl-CoA synthetase 0.0037 0.0183 0.3922
Entamoeba histolytica hypothetical protein 0.0083 0.0495 0.0495
Toxoplasma gondii HEAT repeat-containing protein 0.0018 0.0045 0.0045
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.003 0.0131 0.0131
Loa Loa (eye worm) hypothetical protein 0.0013 0.0015 0.0015
Brugia malayi Dopamine receptor protein 2 0.0027 0.0112 0.0112
Schistosoma mansoni voltage-gated potassium channel 0.0071 0.0416 0.0416
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0013 0.0015 0.0015
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0049 0.026 0.026
Trypanosoma brucei cAMP binding protein, putative 0.0032 0.0148 0.0148
Trichomonas vaginalis adenylate cyclase, putative 0.0023 0.008 0.0457
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0038 0.0187 0.0187
Schistosoma mansoni voltage-gated potassium channel 0.0016 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0028 0.0118 0.0118
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0037 0.0183 0.3922
Schistosoma mansoni hypothetical protein 0.0012 0.0007 0.0007
Echinococcus granulosus transient receptor potential cation channel 0.0016 0.0036 0.0036
Trypanosoma brucei cyclic nucleotide-binding domain containing protein, putative 0.0032 0.0148 0.0148
Trichomonas vaginalis guanylate cyclase, putative 0.0023 0.008 0.0457
Mycobacterium ulcerans esterase/lipase LipP 0.0038 0.0187 0.3999
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0032 0.0148 0.0148
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0027 0.0112 0.0112
Schistosoma mansoni hypothetical protein 0.0021 0.007 0.007
Loa Loa (eye worm) hypothetical protein 0.0016 0.0036 0.0036
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0021 0.007 0.007
Schistosoma mansoni jumonji domain containing protein 0.0055 0.0303 0.0303
Toxoplasma gondii LsmAD domain-containing protein 0.0027 0.0108 0.0108
Trichomonas vaginalis cAMP-dependent protein kinase type I-beta regulatory subunit, putative 0.0032 0.0148 0.0848
Echinococcus granulosus g protein coupled receptor 0.0027 0.0112 0.0112
Schistosoma mansoni similar to Protein C20orf152 homolog 0.0032 0.0148 0.0148
Brugia malayi G protein-coupled receptor 0.0027 0.0112 0.0112
Echinococcus granulosus tachykinin peptides receptor 99D 0.0027 0.0112 0.0112
Onchocerca volvulus 0.1457 1 1
Schistosoma mansoni survival motor neuron protein 0.0212 0.1391 0.1391
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0037 0.0183 0.3922
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0154 0.0154
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0027 0.0112 0.0112
Onchocerca volvulus 0.0014 0.0019 0.0019
Echinococcus multilocularis tumor protein p63 0.0244 0.1612 0.1612
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.003 0.0131 0.0131
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0112
Loa Loa (eye worm) hypothetical protein 0.0016 0.0036 0.0036
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0016 0.0036 0.0036
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0016 0.0036 0.0036
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0027 0.0112 0.0112
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0071 0.0416 0.0416
Brugia malayi Hexokinase family protein 0.1457 1 1
Plasmodium vivax rap guanine nucleotide exchange factor, putative 0.0032 0.0148 0.0148
Echinococcus granulosus rhodopsin orphan GPCR 0.0027 0.0112 0.0112
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0013 0.0015 0.0015
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0038 0.0187 0.1165
Mycobacterium leprae Probable lipase LipE 0.0038 0.0187 0.3999
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0035 0.0169 0.0967
Echinococcus granulosus mothers against decapentaplegic 5 0.0025 0.0094 0.0094
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0027 0.0112 0.0112
Onchocerca volvulus Bile acid receptor homolog 0.0013 0.0015 0.0015
Schistosoma mansoni hypothetical protein 0.0035 0.0166 0.0166
Trichomonas vaginalis guanylate cyclase, putative 0.0023 0.008 0.0457
Echinococcus granulosus single minded 2 0.0023 0.008 0.008
Brugia malayi Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit 0.0016 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0084 0.0509 0.0509
Echinococcus granulosus hexokinase 0.1457 1 1
Loa Loa (eye worm) hypothetical protein 0.104 0.7118 0.7118
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0031 0.0137 0.0784
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0112
Brugia malayi 6-phosphofructokinase 0.0078 0.0467 0.0467
Entamoeba histolytica phosphofructokinase, putative 0.0078 0.0467 0.0467
Onchocerca volvulus 0.0043 0.0219 0.0219
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0032 0.0148 0.0148
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0112
Mycobacterium tuberculosis Probable hydrolase 0.0038 0.0187 0.1165
Brugia malayi Ryanodine Receptor TM 4-6 family protein 0.0016 0.0036 0.0036
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0038 0.0187 0.1165
Leishmania major hypothetical protein, conserved 0.0016 0.0036 0.0036
Echinococcus multilocularis GA binding protein alpha chain 0.0071 0.0413 0.0413
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0105 0.0648 0.0648
Echinococcus granulosus geminin 0.0103 0.0637 0.0637
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0112
Loa Loa (eye worm) hypothetical protein 0.0463 0.3128 0.3128
Schistosoma mansoni ets-related 0.0215 0.1409 0.1409
Echinococcus granulosus tumor protein p63 0.0244 0.1612 0.1612
Loa Loa (eye worm) voltage-gated calcium channel 0.0016 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0027 0.0108 0.0108
Schistosoma mansoni transient receptor potential channel 0.0016 0.0036 0.0036
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0013 0.0015 0.0015
Mycobacterium ulcerans hypothetical protein 0.0038 0.0187 0.3999
Trichomonas vaginalis adenylate cyclase, putative 0.0023 0.008 0.0457
Brugia malayi Intermediate filament tail domain containing protein 0.0036 0.0175 0.0175
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0231 0.1525 0.1525
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0035 0.0169 0.0169
Leishmania major 4-coumarate:coa ligase-like protein 0.0037 0.0183 0.0183
Leishmania major hypothetical protein, unknown function 0.0016 0.0036 0.0036
Echinococcus multilocularis sex peptide receptor 0.0027 0.0112 0.0112
Onchocerca volvulus 0.0038 0.0187 0.0187
Brugia malayi larval opioid receptor 0.0027 0.0112 0.0112
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0033 0.0154 0.0154
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0027 0.0112 0.0112
Brugia malayi N-terminal motif family protein 0.0032 0.0148 0.0148
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0013 0.0015 0.0015
Brugia malayi Smad1 0.0025 0.0094 0.0094
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0023 0.008 0.0457
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0038 0.0187 0.1165
Trichomonas vaginalis phosphofructokinase, putative 0.0021 0.0071 0.0404
Schistosoma mansoni smad1 5 8 and 0.0025 0.0094 0.0094
Loa Loa (eye worm) hypothetical protein 0.0021 0.007 0.007
Echinococcus multilocularis voltage gated potassium channel 0.0016 0.0036 0.0036
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0013 0.0015 0.0087
Onchocerca volvulus 0.1457 1 1
Plasmodium vivax acyl-CoA synthetase, putative 0.0028 0.0118 0.0118
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0112
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0027 0.0112 0.0112
Echinococcus granulosus somatostatin receptor 0.0027 0.0112 0.0112
Brugia malayi ecdysteroid receptor 0.0013 0.0015 0.0015
Echinococcus multilocularis two pore calcium channel protein 1 0.0016 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0074 0.0436 0.0436
Mycobacterium ulcerans lipase LipD 0.0038 0.0187 0.3999
Loa Loa (eye worm) phosphofructokinase 0.0078 0.0467 0.0467
Echinococcus multilocularis rhodopsin orphan GPCR 0.0027 0.0112 0.0112
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0187 0.1069
Brugia malayi Hypothetical UPF0028 protein ZK370.4 in chromosome III, putative 0.0032 0.0148 0.0148
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0112
Trichomonas vaginalis adenylate cyclase, putative 0.0023 0.008 0.0457
Trichomonas vaginalis hypothetical protein 0.0023 0.008 0.0457
Echinococcus granulosus biogenic amine 5HT receptor 0.0027 0.0112 0.0112
Schistosoma mansoni hypothetical protein 0.0035 0.0166 0.0166
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0027 0.0112 0.0112
Plasmodium falciparum hexokinase 0.1457 1 1
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0021 0.0071 0.0071
Trichomonas vaginalis adenylate cyclase, putative 0.0023 0.008 0.0457
Entamoeba histolytica hypothetical protein 0.0014 0.0022 0.0022
Schistosoma mansoni 60S ribosomal protein L21 0.0039 0.0192 0.0192
Brugia malayi Ets-domain containing protein 0.0071 0.0413 0.0413
Trichomonas vaginalis phosphofructokinase, putative 0.0021 0.0071 0.0404
Echinococcus granulosus two pore calcium channel protein 1 0.0016 0.0036 0.0036
Loa Loa (eye worm) ryanodine receptor 0.0016 0.0036 0.0036
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0013 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0387 0.2598 0.2598
Schistosoma mansoni voltage-gated cation channel 0.0016 0.0036 0.0036
Echinococcus granulosus potassium voltage gated channel protein 0.0016 0.0036 0.0036
Schistosoma mansoni alpha-1 adrenergic receptor 0.0027 0.0112 0.0112
Echinococcus multilocularis hexokinase 0.1457 1 1
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0013 0.0015 0.0015
Echinococcus multilocularis short transient receptor potential channel 6 0.0016 0.0036 0.0036
Schistosoma mansoni voltage-gated potassium channel 0.0016 0.0036 0.0036
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0012 0.0007 0.0007
Giardia lamblia CAMP-dependent protein kinase regulatory chain 0.0032 0.0148 1
Schistosoma mansoni voltage-gated potassium channel 0.0071 0.0416 0.0416
Mycobacterium ulcerans beta-lactamase 0.0038 0.0187 0.3999
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0154 0.0154
Plasmodium falciparum cGMP-dependent protein kinase 0.0032 0.0148 0.0148
Echinococcus multilocularis rhodopsin orphan GPCR 0.0027 0.0112 0.0112
Brugia malayi hypothetical protein 0.0027 0.0112 0.0112
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.0032 0.0148 0.0148
Echinococcus granulosus cAMP dependent protein kinase type II regulatory 0.0032 0.0148 0.0148
Schistosoma mansoni ap endonuclease 0.003 0.0131 0.0131
Brugia malayi steroid hormone receptor 0.0013 0.0015 0.0015
Brugia malayi Voltage-gated calcium channel, alpha subunit 0.0016 0.0036 0.0036
Trypanosoma brucei importin beta-1 subunit, putative 0.0018 0.0045 0.0045
Loa Loa (eye worm) MH1 domain-containing protein 0.0025 0.0094 0.0094
Entamoeba histolytica hypothetical protein 0.0083 0.0495 0.0495
Echinococcus multilocularis neuropeptide s receptor 0.0027 0.0112 0.0112
Trichomonas vaginalis alpha-glucosidase, putative 0.0013 0.0015 0.0087
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0169 0.0967
Echinococcus multilocularis transient receptor potential cation channel 0.0016 0.0036 0.0036
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0016 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0037 0.0183 0.0183
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.003 0.0131 0.0131
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0049 0.026 0.026
Echinococcus multilocularis G-protein coupled receptor, putative 0.0027 0.0112 0.0112
Echinococcus granulosus neuropeptide FF receptor 2 0.0027 0.0112 0.0112
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0016 0.0036 0.0036
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0023 0.008 0.0457
Echinococcus granulosus 7TM GPCR rhodopsin 0.0027 0.0112 0.0112
Trichomonas vaginalis guanylate cyclase, putative 0.0023 0.008 0.0457
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0013 0.0015 0.0015
Echinococcus granulosus neuropeptides capa receptor 0.0027 0.0112 0.0112
Schistosoma mansoni cellular tumor antigen P53 0.0036 0.0171 0.0171
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0026 0.0107 0.0667
Echinococcus granulosus ryanodine receptor 44f 0.0016 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0112
Brugia malayi AMP-binding enzyme family protein 0.0037 0.0183 0.0183
Onchocerca volvulus 0.0032 0.0148 0.0148
Schistosoma mansoni lamin 0.0036 0.0175 0.0175
Trichomonas vaginalis adenylate cyclase, putative 0.0023 0.008 0.0457
Brugia malayi neuropeptide F receptor 0.0027 0.0112 0.0112
Echinococcus granulosus fmrfamide receptor 0.0027 0.0112 0.0112
Echinococcus granulosus potassium voltage gated channel protein 0.0016 0.0036 0.0036
Echinococcus multilocularis neuropeptides capa receptor 0.0027 0.0112 0.0112
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0013 0.0015 0.0015
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0027 0.0112 0.0112
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0033 0.0154 0.0154
Echinococcus granulosus allatostatin A receptor 0.0027 0.0112 0.0112
Leishmania major hexokinase, putative 0.1457 1 1
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0013 0.0015 0.0015
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0013 0.0015 0.0087
Echinococcus multilocularis rhodopsin orphan GPCR 0.0027 0.0112 0.0112
Trichomonas vaginalis alpha-glucosidase, putative 0.0013 0.0015 0.0087
Echinococcus multilocularis sterol regulatory element binding protein 0.0036 0.0175 0.0175
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.0108 0.0108
Brugia malayi nuclear hormone receptor 0.0013 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0016 0.0036 0.0036
Leishmania major protein kinase A regulatory subunit, putative 0.0032 0.0148 0.0148
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.008 0.0457
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0016 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0112
Echinococcus granulosus cGMP dependent protein kinase 0.0032 0.0148 0.0148
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0013 0.0015 0.0015
Loa Loa (eye worm) cytochrome P450 family protein 0.0013 0.0014 0.0014
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0016 0.0036 0.0036
Trichomonas vaginalis guanylate cyclase, putative 0.0023 0.008 0.0457
Schistosoma mansoni voltage-gated potassium channel 0.0268 0.1778 0.1778
Brugia malayi CHE-14 protein 0.0036 0.0175 0.0175
Plasmodium falciparum phd finger protein, putative 0.0021 0.007 0.007
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.0258 0.0258
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0078 0.0467 0.2912
Echinococcus multilocularis short transient receptor potential channel 6 0.0016 0.0036 0.0036
Schistosoma mansoni voltage-gated potassium channel 0.0039 0.0192 0.0192
Schistosoma mansoni voltage-gated ion channel 0.0016 0.0036 0.0036
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0027 0.0112 0.0112
Schistosoma mansoni voltage-gated potassium channel 0.0016 0.0036 0.0036
Mycobacterium tuberculosis Probable transcriptional regulatory protein Cmr 0.0032 0.0148 0.0924
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0013 0.0015 0.0015
Echinococcus multilocularis jumonji domain containing protein 0.0029 0.0127 0.0127
Schistosoma mansoni voltage-gated potassium channel 0.0016 0.0036 0.0036
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0035 0.0169 0.0967
Leishmania major cyclic nucleotide-binding protein-like protein 0.0032 0.0148 0.0148
Echinococcus multilocularis transient receptor potential cation channel 0.0016 0.0036 0.0036
Echinococcus multilocularis lysine specific demethylase 5A 0.0025 0.01 0.01
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0016 0.0036 0.0036
Echinococcus granulosus ecdysone induced protein 78C 0.0013 0.0015 0.0015
Echinococcus granulosus 6 phosphofructokinase 0.0078 0.0467 0.0467
Toxoplasma gondii transporter, solute:sodium symporter (SSS) family protein 0.0043 0.0219 0.0219
Trichomonas vaginalis adenylate cyclase, putative 0.0023 0.008 0.0457
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0112
Trichomonas vaginalis guanylate cyclase, putative 0.0023 0.008 0.0457
Trypanosoma cruzi cAMP response protein 1, putative 0.0032 0.0148 0.0148
Brugia malayi 6-phosphofructokinase 0.0078 0.0467 0.0467
Trichomonas vaginalis adenylate cyclase, putative 0.0023 0.008 0.0457
Schistosoma mansoni inositol transporter 0.0043 0.0219 0.0219
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.008 0.0457
Trichomonas vaginalis adenylate cyclase type IX, putative 0.0023 0.008 0.0457
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0027 0.0112 0.0112
Loa Loa (eye worm) PHD-finger family protein 0.0021 0.007 0.007
Echinococcus granulosus voltage dependent calcium channel 0.0016 0.0036 0.0036
Trypanosoma cruzi cAMP binding protein, putative 0.0032 0.0148 0.0148
Echinococcus granulosus survival motor neuron protein 1 0.104 0.7118 0.7118
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0023 0.008 0.0457
Echinococcus multilocularis lysosomal alpha glucosidase 0.016 0.1028 0.1028
Onchocerca volvulus 0.0027 0.0112 0.0112
Toxoplasma gondii PHD-finger domain-containing protein 0.0021 0.007 0.007
Echinococcus granulosus neuropeptide receptor 0.0027 0.0112 0.0112
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0036 0.0175 0.0175
Echinococcus multilocularis rhodopsin orphan GPCR 0.0027 0.0112 0.0112
Brugia malayi RNA, U transporter 1 0.005 0.0269 0.0269
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0013 0.0015 0.0015
Echinococcus granulosus cAMP dependent protein kinase type I beta 0.0032 0.0148 0.0148
Loa Loa (eye worm) hypothetical protein 0.0016 0.0036 0.0036
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0013 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0049 0.026 0.026
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0245 0.1622 0.1622
Echinococcus granulosus neuropeptide Y receptor 0.0027 0.0112 0.0112
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0036 0.0175 0.0175
Echinococcus multilocularis lamin dm0 0.0036 0.0175 0.0175
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.008 0.0457
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0112
Echinococcus multilocularis lysosomal alpha glucosidase 0.016 0.1028 0.1028
Echinococcus multilocularis transfer RNA-Gly 0.0016 0.0036 0.0036
Schistosoma mansoni opsin-like receptor 0.0027 0.0112 0.0112
Leishmania major hexokinase, putative 0.1457 1 1
Brugia malayi G protein-coupled receptor F59B2.13 0.0027 0.0112 0.0112
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0112
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0112
Schistosoma mansoni steroid hormone receptor ad4bp 0.0013 0.0015 0.0015
Trichomonas vaginalis guanylate cyclase, putative 0.0023 0.008 0.0457
Schistosoma mansoni serine/threonine protein kinase 0.0032 0.0148 0.0148
Mycobacterium ulcerans transmembrane transport protein 0.0032 0.0148 0.3172
Loa Loa (eye worm) hexokinase 0.1457 1 1
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0049 0.026 0.026
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0083 0.0495 0.0495
Echinococcus granulosus hypothetical protein 0.0027 0.0112 0.0112
Echinococcus multilocularis microtubule associated protein 2 0.0975 0.6669 0.6669
Leishmania major 4-coumarate:coa ligase-like protein 0.0037 0.0183 0.0183
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0013 0.0015 0.0015
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0013 0.0015 0.0015
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.008 0.0457
Echinococcus multilocularis sodium leak channel non selective protein 0.0016 0.0036 0.0036
Echinococcus granulosus sodium:glucose cotransporter 0.0043 0.0219 0.0219
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0112
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0013 0.0015 0.0015
Brugia malayi Niemann-Pick C1 protein precursor 0.0084 0.0509 0.0509
Echinococcus multilocularis potassium large conductance calcium activated 0.0016 0.0036 0.0036
Trichomonas vaginalis ap endonuclease, putative 0.003 0.0131 0.0749
Mycobacterium tuberculosis Probable lipase LipD 0.0038 0.0187 0.1165
Echinococcus granulosus cAMP dependent protein kinase regulatory 0.0032 0.0148 0.0148
Trichomonas vaginalis adenylate cyclase, putative 0.0023 0.008 0.0457
Loa Loa (eye worm) hypothetical protein 0.0028 0.0118 0.0118
Onchocerca volvulus 0.0027 0.0112 0.0112
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0016 0.0036 0.0036
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0013 0.0015 0.0015
Leishmania major protein kinase, putative 0.0032 0.0148 0.0148
Schistosoma mansoni 6-phosphofructokinase 0.0078 0.0467 0.0467
Treponema pallidum hexokinase (hxk) 0.1457 1 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0027 0.0112 0.0112
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0112
Echinococcus multilocularis orexin receptor type 2 0.0027 0.0112 0.0112
Brugia malayi MH1 domain containing protein 0.0014 0.0018 0.0018
Schistosoma mansoni voltage-gated potassium channel KCNQ 0.0016 0.0036 0.0036
Mycobacterium tuberculosis Conserved protein 0.0038 0.0187 0.1165
Loa Loa (eye worm) hypothetical protein 0.0213 0.1398 0.1398
Trichomonas vaginalis guanylate cyclase, putative 0.0023 0.008 0.0457
Entamoeba histolytica Ran family GTPase 0.0013 0.0013 0.0013
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0027 0.0112 0.0112
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0023 0.008 0.0457
Mycobacterium ulcerans regulatory protein 0.0032 0.0148 0.3172
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0112
Echinococcus granulosus short transient receptor potential channel 6 0.0016 0.0036 0.0036
Trypanosoma cruzi regulatory subunit of protein kinase a-like protein, putative 0.0032 0.0148 0.0148
Brugia malayi MH1 domain containing protein 0.0025 0.0094 0.0094
Schistosoma mansoni high-affinity choline transporter 0.0387 0.2598 0.2598
Echinococcus multilocularis FTZ F1 alpha 0.0013 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0016 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0043 0.0219 0.0219
Echinococcus granulosus Niemann Pick C1 protein 0.0121 0.0759 0.0759
Echinococcus granulosus hexokinase 0.1457 1 1
Schistosoma mansoni hypothetical protein 0.0103 0.0637 0.0637
Brugia malayi hypothetical protein 0.0017 0.0043 0.0043
Echinococcus multilocularis solute carrier family 5 0.0043 0.0219 0.0219
Echinococcus granulosus g protein coupled receptor 0.0027 0.0112 0.0112
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0013 0.0015 0.0015
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0021 0.0071 0.0071
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0032 0.0148 0.0148
Echinococcus multilocularis two pore calcium channel protein 2 0.0016 0.0036 0.0036
Onchocerca volvulus 0.0036 0.0171 0.0171
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0027 0.0112 0.0112
Loa Loa (eye worm) transcription factor SMAD2 0.0361 0.2418 0.2418
Leishmania major hypothetical protein, conserved 0.0038 0.0187 0.0187
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0013 0.0015 0.0015
Echinococcus multilocularis neuropeptide receptor A26 0.0027 0.0112 0.0112
Echinococcus multilocularis PHD finger protein rhinoceros 0.0021 0.007 0.007
Entamoeba histolytica hexokinase 2 0.1457 1 1
Echinococcus multilocularis fmrfamide receptor 0.0027 0.0112 0.0112
Mycobacterium ulcerans 6-phosphofructokinase 0.0078 0.0467 1
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0027 0.0112 0.0112
Echinococcus multilocularis fmrfamide receptor 0.0027 0.0112 0.0112
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0012 0.0007 0.0007
Loa Loa (eye worm) fli-1 protein 0.0215 0.1409 0.1409
Trichomonas vaginalis adenylate cyclase type, putative 0.0023 0.008 0.0457
Echinococcus multilocularis calcium activated potassium channel 0.0016 0.0036 0.0036
Echinococcus multilocularis geminin 0.0103 0.0637 0.0637
Echinococcus granulosus intermediate filament protein 0.0036 0.0175 0.0175
Brugia malayi hypothetical protein 0.0027 0.0112 0.0112
Trypanosoma brucei cyclic nucleotide-binding domain containing protein, putative 0.0032 0.0148 0.0148
Echinococcus granulosus beta LACTamase domain containing family member 0.0038 0.0187 0.0187
Plasmodium vivax hexokinase, putative 0.1457 1 1
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.003 0.0131 0.2801
Trichomonas vaginalis guanylate cyclase, putative 0.0023 0.008 0.0457
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.008 0.0457
Schistosoma mansoni adenoreceptor 0.0027 0.0112 0.0112
Loa Loa (eye worm) hypothetical protein 0.0016 0.0036 0.0036
Echinococcus multilocularis dro:myosuppressin receptor 0.0027 0.0112 0.0112
Brugia malayi G-protein coupled receptor 0.0027 0.0112 0.0112
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0027 0.0112 0.0112
Loa Loa (eye worm) hypothetical protein 0.0028 0.0118 0.0118
Brugia malayi Ets-domain containing protein 0.0071 0.0413 0.0413
Onchocerca volvulus 0.0263 0.1746 0.1746
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0032 0.0148 0.0148
Brugia malayi Pre-SET motif family protein 0.0231 0.1525 0.1525
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0023 0.008 0.0457
Schistosoma mansoni smad1 5 8 and 0.0025 0.0094 0.0094
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0028 0.0115 0.0115
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0112
Schistosoma mansoni amine GPCR 0.0027 0.0112 0.0112
Loa Loa (eye worm) MH2 domain-containing protein 0.0361 0.2418 0.2418
Brugia malayi hypothetical protein 0.0027 0.0112 0.0112
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0028 0.0118 0.0733
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0023 0.008 0.0457
Onchocerca volvulus 0.0914 0.6245 0.6245
Entamoeba histolytica hypothetical protein 0.0083 0.0495 0.0495
Echinococcus granulosus shaker cognate 0.0016 0.0036 0.0036
Echinococcus multilocularis conserved hypothetical protein 0.0016 0.0036 0.0036
Schistosoma mansoni biogenic amine receptor 0.0027 0.0112 0.0112
Echinococcus multilocularis cAMP dependent protein kinase type I beta 0.0032 0.0148 0.0148
Schistosoma mansoni voltage-gated potassium channel 0.0016 0.0036 0.0036
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0013 0.0013 0.0013
Brugia malayi Voltage-gated potassium channel, KCNQ (Kv7-like) alpha-subunit. C. elegans kqt-1 ortholog 0.0016 0.0036 0.0036
Brugia malayi Cyclic-nucleotide gated cation channel 0.0049 0.026 0.026
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0112
Echinococcus granulosus histone lysine methyltransferase setb 0.0033 0.0154 0.0154
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0025 0.0094 0.0094
Loa Loa (eye worm) hypothetical protein 0.0013 0.0015 0.0015
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0013 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0112
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0212 0.1391 0.1391
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0112
Loa Loa (eye worm) hypothetical protein 0.0019 0.0055 0.0055
Toxoplasma gondii transporter, cation channel family protein 0.0016 0.0036 0.0036
Trichomonas vaginalis maltase-glucoamylase, putative 0.0013 0.0015 0.0087
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0013 0.0015 0.0015
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0027 0.0112 0.0112
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0016 0.0036 0.0036
Brugia malayi sulfakinin receptor protein 0.0027 0.0112 0.0112
Loa Loa (eye worm) hexokinase 0.0914 0.6245 0.6245
Loa Loa (eye worm) hypothetical protein 0.0016 0.0036 0.0036
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0032 0.0148 0.0148
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0078 0.0467 0.0467
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0027 0.0112 0.0112
Mycobacterium ulcerans acyl-CoA synthetase 0.0037 0.0183 0.3922
Onchocerca volvulus 0.0212 0.1391 0.1391
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0154 0.0154
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0187 0.0187
Trichomonas vaginalis guanylate cyclase, putative 0.0023 0.008 0.0457
Trypanosoma cruzi regulatory subunit of protein kinase a-like protein, putative 0.0032 0.0148 0.0148
Echinococcus granulosus patatin phospholipase domain containing protein 0.0032 0.0148 0.0148
Brugia malayi G-protein coupled receptor 0.0027 0.0112 0.0112
Brugia malayi follicle stimulating hormone receptor 0.0027 0.0112 0.0112
Echinococcus multilocularis potassium voltage gated channel protein 0.0016 0.0036 0.0036
Loa Loa (eye worm) voltage-dependent calcium channel 0.0016 0.0036 0.0036
Plasmodium vivax 6-phosphofructokinase, putative 0.0021 0.0071 0.0071
Mycobacterium tuberculosis Conserved hypothetical protein 0.0032 0.0148 0.0924
Echinococcus multilocularis voltage gated hydrogen channel 1 0.0016 0.0036 0.0036
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.0258 0.0258
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0016 0.0036 0.0036
Onchocerca volvulus Huntingtin homolog 0.0074 0.0436 0.0436
Trichomonas vaginalis guanylate cyclase, putative 0.0023 0.008 0.0457
Loa Loa (eye worm) jmjC domain-containing protein 0.0025 0.01 0.01
Echinococcus multilocularis transient receptor potential cation channel 0.0016 0.0036 0.0036
Mycobacterium ulcerans hypothetical protein 0.0032 0.0148 0.3172
Brugia malayi MH2 domain containing protein 0.0025 0.0094 0.0094
Onchocerca volvulus 0.0027 0.0112 0.0112
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0069 0.0401 0.0401
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0013 0.0013 0.0013
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0037 0.0183 0.3922
Entamoeba histolytica acyl-coA synthetase, putative 0.0037 0.0183 0.0183
Schistosoma mansoni transient receptor potential channel 4 0.0016 0.0036 0.0036
Schistosoma mansoni growth hormone secretagogue receptor 0.0027 0.0112 0.0112
Brugia malayi MH1 domain containing protein 0.0014 0.0018 0.0018
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0078 0.0467 0.0399
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0027 0.0112 0.0112
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0013 0.0015 0.0015
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0032 0.0148 0.0148
Schistosoma mansoni hypothetical protein 0.0027 0.0112 0.0112
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0013 0.0015 0.0015
Echinococcus granulosus rhodopsin orphan GPCR 0.0027 0.0112 0.0112
Schistosoma mansoni neuropeptide receptor 0.0027 0.0112 0.0112
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0013 0.0013 0.0013
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0013 0.0015 0.0015
Leishmania major hypothetical protein, conserved 0.0032 0.0148 0.0148
Brugia malayi hypothetical protein 0.0027 0.0112 0.0112
Loa Loa (eye worm) 6-phosphofructokinase 0.0078 0.0467 0.0467
Trypanosoma cruzi cyclic nucleotide-binding domain containing protein, putative 0.0032 0.0148 0.0148
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0112
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0243 0.1603 1
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0112
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0027 0.0112 0.0112
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0016 0.0036 0.0036
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0027 0.0112 0.0112
Loa Loa (eye worm) hypothetical protein 0.0033 0.0154 0.0154
Brugia malayi hypothetical protein 0.0027 0.0112 0.0112
Echinococcus granulosus 7tm_1 domain containing protein 0.0027 0.0112 0.0112
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0027 0.0112 0.0112
Trichomonas vaginalis guanylate cyclase, putative 0.0023 0.008 0.0457
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0016 0.0036 0.0036
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0037 0.0183 0.1142
Brugia malayi PHD-finger family protein 0.0021 0.007 0.007
Schistosoma mansoni hexokinase 0.1457 1 1
Echinococcus multilocularis sodium:glucose cotransporter 2 0.0043 0.0219 0.0219
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0013 0.0015 0.0015
Brugia malayi Importin beta-1 subunit 0.0018 0.0045 0.0045
Echinococcus multilocularis hexokinase type 2 0.1457 1 1
Echinococcus multilocularis musashi 0.0036 0.0175 0.0175
Loa Loa (eye worm) intermediate filament protein 0.0036 0.0175 0.0175
Echinococcus multilocularis patatin phospholipase domain containing protein 0.0032 0.0148 0.0148
Mycobacterium tuberculosis Conserved protein 0.0038 0.0187 0.1165
Loa Loa (eye worm) TYRA-2 protein 0.0027 0.0112 0.0112
Echinococcus multilocularis lamin 0.0036 0.0175 0.0175
Echinococcus multilocularis transient receptor potential cation channel 0.0016 0.0036 0.0036
Echinococcus multilocularis voltage dependent calcium channel 0.0016 0.0036 0.0036
Schistosoma mansoni voltage-gated potassium channel 0.0049 0.026 0.026
Schistosoma mansoni ran 0.0013 0.0013 0.0013
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0023 0.008 0.0457
Brugia malayi ORL1-like opioid receptor 0.0027 0.0112 0.0112
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0049 0.026 0.1488
Echinococcus multilocularis g protein coupled receptor 0.0027 0.0112 0.0112
Echinococcus multilocularis G protein coupled receptor 139 0.0027 0.0112 0.0112
Loa Loa (eye worm) melatonin receptor type 1A 0.0027 0.0112 0.0112
Echinococcus multilocularis potassium voltage gated channel protein 0.0016 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0038 0.0187 0.0187
Loa Loa (eye worm) hypothetical protein 0.0016 0.0036 0.0036
Brugia malayi Sodium:solute symporter family protein 0.0043 0.0219 0.0219
Onchocerca volvulus 0.0027 0.0112 0.0112
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0112
Schistosoma mansoni camp-dependent rap1 guanine-nucleotide exchange factor 0.0032 0.0148 0.0148
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0026 0.0107 0.0667
Brugia malayi Serotonin receptor 0.0027 0.0112 0.0112
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0016 0.0036 0.0036
Echinococcus granulosus tm gpcr rhodopsin 0.0027 0.0112 0.0112
Trichomonas vaginalis adenylate cyclase, putative 0.0023 0.008 0.0457
Loa Loa (eye worm) neuropeptide F receptor 0.0027 0.0112 0.0112
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0083 0.0495 0.0495
Trypanosoma cruzi importin beta-1 subunit, putative 0.0014 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0017 0.0041 0.0041
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0031 0.0137 0.0137
Brugia malayi AMP-binding enzyme family protein 0.0037 0.0183 0.0183
Loa Loa (eye worm) hexokinase 0.0451 0.3042 0.3042
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0016 0.0036 0.0036
Onchocerca volvulus 0.0027 0.0112 0.0112
Toxoplasma gondii hypothetical protein 0.0016 0.0036 0.0036
Mycobacterium ulcerans acyl-CoA synthetase 0.0037 0.0183 0.3922
Toxoplasma gondii cAMP-dependent protein kinase regulatory subunit 0.0032 0.0148 0.0148
Loa Loa (eye worm) hypothetical protein 0.0038 0.0187 0.0187
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0169 0.0967
Schistosoma mansoni neuropathy target esterase/swiss cheese-related protein 0.0032 0.0148 0.0148
Trichomonas vaginalis adenylate cyclase, putative 0.0023 0.008 0.0457
Schistosoma mansoni amine GPCR 0.0027 0.0112 0.0112
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0169 0.0967
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0035 0.0169 0.0169
Echinococcus granulosus cGMP dependent protein kinase 1 0.0032 0.0148 0.0148
Loa Loa (eye worm) hypothetical protein 0.0016 0.0036 0.0036
Loa Loa (eye worm) ion channel NompC 0.0016 0.0036 0.0036
Echinococcus granulosus tm gpcr rhodopsin 0.0027 0.0112 0.0112
Echinococcus multilocularis survival motor neuron protein 1 0.104 0.7118 0.7118
Brugia malayi Glycosyl hydrolases family 31 protein 0.0013 0.0015 0.0015
Onchocerca volvulus 0.0027 0.0112 0.0112
Echinococcus granulosus neuropeptides capa receptor 0.0027 0.0112 0.0112
Schistosoma mansoni biogenic amine (5HT) receptor 0.0027 0.0112 0.0112
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0027 0.0112 0.0112
Echinococcus granulosus potassium voltage gated channel protein 0.0016 0.0036 0.0036
Echinococcus multilocularis beta LACTamase domain containing family member 0.0038 0.0187 0.0187
Schistosoma mansoni myosin xvIII 0.0027 0.0112 0.0112
Trypanosoma brucei glucosidase, putative 0.0035 0.0169 0.0169
Leishmania major glycosyl hydrolase-like protein 0.0013 0.0015 0.0015
Echinococcus granulosus potassium voltage gated channel protein 0.0016 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0112
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0016 0.0036 0.0036
Brugia malayi Dopamine receptor 0.0027 0.0112 0.0112
Echinococcus granulosus Potassium voltage gated channel protein Shaw 0.0016 0.0036 0.0036
Echinococcus multilocularis g protein coupled receptor 0.0027 0.0112 0.0112
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0112
Loa Loa (eye worm) G-protein coupled receptor 0.0027 0.0112 0.0112
Loa Loa (eye worm) hypothetical protein 0.0036 0.0171 0.0171
Schistosoma mansoni opsin-like receptor 0.0027 0.0112 0.0112
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0013 0.0015 0.0015
Echinococcus granulosus neuropeptide Y receptor 0.0027 0.0112 0.0112
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0016 0.0036 0.0036
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0049 0.026 0.026
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0013 0.0015 0.0015
Brugia malayi MH1 domain containing protein 0.0025 0.0094 0.0094
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0013 0.0013 0.0013
Schistosoma mansoni coup transcription factor 0.0013 0.0015 0.0015
Echinococcus multilocularis voltage gated potassium channel 0.0071 0.0416 0.0416
Schistosoma mansoni importin beta-1 0.0018 0.0045 0.0045
Schistosoma mansoni transient receptor potential channel 0.0016 0.0036 0.0036
Echinococcus granulosus transient receptor potential cation channel 0.0016 0.0036 0.0036
Mycobacterium ulcerans hypothetical protein 0.0032 0.0148 0.3172
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0014 0.0022 0.0127
Echinococcus granulosus rhodopsin orphan GPCR 0.0027 0.0112 0.0112
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0013 0.0015 0.0015
Echinococcus granulosus lamin dm0 0.0036 0.0175 0.0175
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.003 0.0131 0.8715
Loa Loa (eye worm) voltage-gated potassium channel 0.0016 0.0036 0.0036
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0013 0.0015 0.0015
Plasmodium falciparum cAMP-dependent protein kinase regulatory subunit 0.0032 0.0148 0.0148
Schistosoma mansoni biogenic amine receptor 0.0027 0.0112 0.0112
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0027 0.0112 0.0112
Loa Loa (eye worm) hypothetical protein 0.0018 0.0045 0.0045
Schistosoma mansoni neuropeptide f receptor 76f 0.0027 0.0112 0.0112
Brugia malayi Cyclic-nucleotide gated cation channel, C. elegans tax-4 ortholog 0.0032 0.0148 0.0148
Echinococcus multilocularis neutral alpha glucosidase AB 0.0035 0.0169 0.0169
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0016 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0037 0.0183 0.0183
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0187 0.1069
Onchocerca volvulus 0.0027 0.0112 0.0112
Echinococcus multilocularis thyroid hormone receptor alpha 0.0013 0.0015 0.0015
Trichomonas vaginalis guanylate cyclase, putative 0.0023 0.008 0.0457
Loa Loa (eye worm) AGC/PKG protein kinase 0.0032 0.0148 0.0148
Onchocerca volvulus 0.0037 0.0183 0.0183
Schistosoma mansoni hypothetical protein 0.0083 0.0495 0.0495
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0112
Echinococcus multilocularis serotonin receptor 0.0027 0.0112 0.0112
Plasmodium vivax SET domain protein, putative 0.0033 0.0154 0.0154
Plasmodium falciparum acyl-CoA synthetase 0.0028 0.0118 0.0118
Leishmania major 4-coumarate:coa ligase-like protein 0.0037 0.0183 0.0183
Loa Loa (eye worm) hypothetical protein 0.0013 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0016 0.0036 0.0036
Treponema pallidum catabolite gene activator (Crp) 0.0032 0.0148 0.0078
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0016 0.0036 0.0036
Echinococcus granulosus rhodopsin orphan GPCR 0.0027 0.0112 0.0112
Echinococcus granulosus Smad4 0.0025 0.0094 0.0094
Echinococcus granulosus transient receptor potential cation channel 0.0016 0.0036 0.0036
Schistosoma mansoni neuropeptide receptor 0.0027 0.0112 0.0112
Loa Loa (eye worm) hypothetical protein 0.0016 0.0036 0.0036
Echinococcus multilocularis shaker cognate 0.0016 0.0036 0.0036
Loa Loa (eye worm) nuclear factor I 0.0014 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0463 0.3128 0.3128
Echinococcus multilocularis hexokinase 0.1457 1 1
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0105 0.0648 0.0648
Echinococcus multilocularis ryanodine receptor 44f 0.0016 0.0036 0.0036
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0033 0.0154 0.0154
Onchocerca volvulus 0.0027 0.0112 0.0112
Echinococcus granulosus sex peptide receptor 0.0027 0.0112 0.0112
Brugia malayi hypothetical protein 0.0027 0.0112 0.0112
Entamoeba histolytica acyl-CoA synthetase, putative 0.0037 0.0183 0.0183
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0037 0.0183 0.1142
Loa Loa (eye worm) hypothetical protein 0.0016 0.0036 0.0036
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0027 0.0112 0.0112
Loa Loa (eye worm) hypothetical protein 0.0016 0.0036 0.0036
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0016 0.0036 0.0036
Onchocerca volvulus Alhambra homolog 0.0021 0.007 0.007
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0169 0.0967
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0027 0.0112 0.0112
Loa Loa (eye worm) hypothetical protein 0.0038 0.0187 0.0187
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0013 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0112
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0112
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.003 0.0131 0.0131
Brugia malayi Steroid receptor seven-up type 2 0.0013 0.0015 0.0015
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0023 0.008 0.0457
Schistosoma mansoni transcription factor LCR-F1 0.0083 0.0495 0.0495
Echinococcus multilocularis potassium voltage gated channel subfamily C 0.0016 0.0036 0.0036
Brugia malayi latrophilin 2 splice variant baaae 0.0019 0.0055 0.0055
Treponema pallidum catabolite gene activator 0.0032 0.0148 0.0078
Loa Loa (eye worm) jmjC domain-containing protein 0.0043 0.0225 0.0225
Trichomonas vaginalis importin beta-1, putative 0.0014 0.0022 0.0127
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0037 0.0183 0.3922
Brugia malayi hypothetical protein 0.0016 0.0036 0.0036
Brugia malayi hypothetical protein 0.0083 0.0495 0.0495
Brugia malayi Cytochrome P450 family protein 0.0013 0.0014 0.0014
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0027 0.0112 0.0112
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0049 0.026 0.026
Plasmodium vivax hypothetical protein, conserved 0.0021 0.007 0.007
Loa Loa (eye worm) hypothetical protein 0.0037 0.0183 0.0183
Loa Loa (eye worm) hexokinase type II 0.1457 1 1
Trichomonas vaginalis adenylate cyclase type III, putative 0.0023 0.008 0.0457
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0169 0.0169
Echinococcus multilocularis neuropeptides capa receptor 0.0027 0.0112 0.0112
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0071 0.0416 0.0416
Trypanosoma cruzi Flagellar Member 6 0.0032 0.0148 0.0148
Schistosoma mansoni opsin-like receptor 0.0027 0.0112 0.0112
Echinococcus multilocularis protein patched 0.0036 0.0175 0.0175
Echinococcus granulosus orexin receptor type 2 0.0027 0.0112 0.0112
Trypanosoma cruzi hexokinase, putative 0.1457 1 1
Schistosoma mansoni histamine h1 receptor 0.0027 0.0112 0.0112
Toxoplasma gondii hypothetical protein 0.0016 0.0036 0.0036
Schistosoma mansoni transient receptor potential channel 0.0016 0.0036 0.0036
Schistosoma mansoni smad1 5 8 and 0.0025 0.0094 0.0094
Mycobacterium tuberculosis Probable conserved transmembrane transport protein 0.0032 0.0148 0.0924
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0038 0.0187 0.0187
Mycobacterium leprae conserved hypothetical protein 0.0038 0.0187 0.3999
Trypanosoma brucei Flagellar Member 6 0.0032 0.0148 0.0148
Mycobacterium ulcerans transcriptional regulatory protein 0.0032 0.0148 0.3172
Echinococcus granulosus high affinity choline transporter 1 0.0387 0.2598 0.2598
Schistosoma mansoni retinoic acid receptor RXR 0.0013 0.0015 0.0015
Echinococcus granulosus importin subunit beta 1 0.0018 0.0045 0.0045
Trichomonas vaginalis adenylate cyclase, putative 0.0023 0.008 0.0457
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0112
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0112
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0187 0.1069
Brugia malayi Egg laying defective protein 4 0.0032 0.0148 0.0148
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0169 0.0169
Brugia malayi Nuclear hormone receptor-like 1 0.0013 0.0015 0.0015
Echinococcus granulosus Protein patched homolog 1 0.0036 0.0175 0.0175
Toxoplasma gondii PHD-finger domain-containing protein 0.0021 0.007 0.007
Echinococcus multilocularis rhodopsin orphan GPCR 0.0027 0.0112 0.0112
Brugia malayi putative neuropeptide receptor 0.0027 0.0112 0.0112
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0021 0.0071 0.0071
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0027 0.0112 0.0112
Schistosoma mansoni hypothetical protein 0.0027 0.0112 0.0112
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0049 0.026 0.026
Brugia malayi Glycosyl hydrolases family 31 protein 0.0035 0.0169 0.0169
Echinococcus multilocularis hyperpolarization activated cyclic 0.0049 0.026 0.026
Echinococcus granulosus hyperpolarization activated cyclic 0.0049 0.026 0.026
Loa Loa (eye worm) G-protein coupled receptor 0.0027 0.0112 0.0112
Schistosoma mansoni RAR-like nuclear receptor 0.0013 0.0015 0.0015
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0027 0.0112 0.0112
Schistosoma mansoni thyroid hormone receptor 0.0013 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0013 0.0015 0.0015
Echinococcus multilocularis 6 phosphofructokinase 0.0078 0.0467 0.0467
Leishmania major hypothetical protein, conserved 0.0032 0.0148 0.0148
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0245 0.1622 0.1622
Echinococcus granulosus expressed conserved protein 0.0079 0.0473 0.0473
Echinococcus multilocularis peregrin 0.0024 0.0087 0.0087
Brugia malayi intermediate filament protein 0.0036 0.0175 0.0175
Echinococcus granulosus peptide allatostatin:somatostatin 0.0027 0.0112 0.0112
Schistosoma mansoni amine GPCR 0.0027 0.0112 0.0112
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0187 0.0187
Trypanosoma cruzi hexokinase, putative 0.1457 1 1
Brugia malayi MH2 domain containing protein 0.0025 0.0094 0.0094
Entamoeba histolytica phosphofructokinase, putative 0.0078 0.0467 0.0467
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0021 0.0071 0.0071
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0027 0.0112 0.0112
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0148 0.0848
Echinococcus granulosus potassium voltage gated channel subfamily A 0.0016 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0028 0.0115 0.0115
Schistosoma mansoni calcium-activated potassium channel 0.0016 0.0036 0.0036
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0016 0.0036 0.0036
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0027 0.0112 0.0112
Loa Loa (eye worm) hypothetical protein 0.0016 0.0036 0.0036
Mycobacterium tuberculosis Conserved protein 0.0032 0.0148 0.0924
Onchocerca volvulus 0.0038 0.0187 0.0187
Onchocerca volvulus 0.0013 0.0015 0.0015
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0027 0.0112 0.0112
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0112
Mycobacterium tuberculosis Probable lipase LipE 0.0038 0.0187 0.1165
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0016 0.0036 0.0036
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.008 0.0457
Echinococcus granulosus neuropeptide s receptor 0.0027 0.0112 0.0112
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0027 0.0112 0.0112
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0086 0.0518 0.0518
Schistosoma mansoni Smad4 0.0025 0.0094 0.0094
Brugia malayi Hexokinase family protein 0.0914 0.6245 0.6245
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0049 0.026 0.026
Giardia lamblia Histone acetyltransferase GCN5 0.0028 0.0119 0.7849
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0013 0.0015 0.0015
Echinococcus granulosus transient receptor potential cation channel 0.0016 0.0036 0.0036
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit. C. elegans egl-36 ortholog 0.0016 0.0036 0.0036
Brugia malayi GnHR receptor homolog 0.0027 0.0112 0.0112
Echinococcus multilocularis sodium:myo inositol cotransporter 0.0043 0.0219 0.0219
Echinococcus granulosus smad 0.0025 0.0094 0.0094
Brugia malayi phosphofructokinase 0.0078 0.0467 0.0467
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0031 0.0137 0.0137
Onchocerca volvulus 0.0016 0.0036 0.0036
Echinococcus multilocularis smad 0.0025 0.0094 0.0094
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0035 0.0169 0.0169
Loa Loa (eye worm) hypothetical protein 0.0016 0.0036 0.0036
Brugia malayi exodeoxyribonuclease III family protein 0.003 0.0131 0.0131
Trichomonas vaginalis phosphofructokinase, putative 0.0021 0.0071 0.0404
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.008 0.0457
Schistosoma mansoni 6-phosphofructokinase 0.0078 0.0467 0.0467
Echinococcus granulosus rhodopsin orphan GPCR 0.0027 0.0112 0.0112
Echinococcus multilocularis mothers against decapentaplegic 5 0.0025 0.0094 0.0094
Brugia malayi cation channel family protein 0.0016 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0112
Trypanosoma brucei hexokinase, putative 0.1457 1 1
Schistosoma mansoni hypothetical protein 0.0027 0.0112 0.0112
Trichomonas vaginalis adenylate cyclase type, putative 0.0023 0.008 0.0457
Loa Loa (eye worm) voltage-gated potassium channel 0.0016 0.0036 0.0036
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0035 0.0169 0.0169
Onchocerca volvulus Huntingtin homolog 0.0074 0.0436 0.0436
Echinococcus multilocularis potassium voltage gated channel protein 0.0016 0.0036 0.0036
Trichomonas vaginalis guanylate cyclase, putative 0.0023 0.008 0.0457
Toxoplasma gondii exonuclease III APE 0.003 0.0131 0.0131
Echinococcus granulosus neuropeptide receptor A26 0.0027 0.0112 0.0112
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0049 0.026 0.026
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0032 0.0148 0.0148
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.0112
Loa Loa (eye worm) steroid hormone receptor 0.0013 0.0015 0.0015
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0187 0.0187
Brugia malayi Dopamine receptor protein 1 0.0027 0.0112 0.0112
Trypanosoma brucei hexokinase 0.1457 1 1
Mycobacterium ulcerans hypothetical protein 0.0037 0.0183 0.3922
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0028 0.0118 0.6061
Schistosoma mansoni hypothetical protein 0.0027 0.0112 0.0112
Schistosoma mansoni voltage-gated potassium channel 0.0016 0.0036 0.0036

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 1.5 uM Inhibition of p56 Lck tyrosine kinase ChEMBL. 9873567
IC50 (binding) = 1.5 uM Inhibition of p56 Lck tyrosine kinase ChEMBL. 9873567

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

No external resources registered for this compound

Bibliographic References

1 literature reference was collected for this gene.

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