Detailed information for compound 1389921

Basic information

Technical information
  • TDR Targets ID: 1389921
  • Name: 4-[(4-nitrophenyl)methylsulfanyl]quinazoline
  • MW: 297.332 | Formula: C15H11N3O2S
  • H donors: 0 H acceptors: 4 LogP: 3.71 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: [O-][N+](=O)c1ccc(cc1)CSc1ncnc2c1cccc2
  • InChi: 1S/C15H11N3O2S/c19-18(20)12-7-5-11(6-8-12)9-21-15-13-3-1-2-4-14(13)16-10-17-15/h1-8,10H,9H2
  • InChiKey: YVAKWSMPQOHQDS-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 4-[(4-nitrophenyl)methylthio]quinazoline
  • 4-[(4-nitrobenzyl)thio]quinazoline
  • SMR000349222
  • ZINC03255298
  • T0512-8264
  • MLS001006203

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens euchromatic histone-lysine N-methyltransferase 2 Starlite/ChEMBL No references
Homo sapiens lysine (K)-specific demethylase 4A Starlite/ChEMBL No references
Homo sapiens muscleblind-like splicing regulator 1 Starlite/ChEMBL No references
Homo sapiens microtubule-associated protein tau Starlite/ChEMBL No references
Mus musculus RAR-related orphan receptor gamma Starlite/ChEMBL No references
Homo sapiens ataxin 2 Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Candida albicans one of two closely related potential jumonji-like transcription factor genes similar to S. cerevisiae RPH1 (YER169W) damage-resp Get druggable targets OG5_127917 All targets in OG5_127917
Echinococcus multilocularis Transcription factor, JmjC domain containing protein Get druggable targets OG5_127917 All targets in OG5_127917
Plasmodium yoelii hypothetical protein Get druggable targets OG5_127917 All targets in OG5_127917
Candida albicans one of two closely related potential jumonji-like transcription factor genes similar to S. cerevisiae RPH1 (YER169W) damage-resp Get druggable targets OG5_127917 All targets in OG5_127917
Echinococcus granulosus Transcription factor JmjC domain containing protein Get druggable targets OG5_127917 All targets in OG5_127917
Brugia malayi jmjC domain containing protein Get druggable targets OG5_127917 All targets in OG5_127917
Echinococcus granulosus microtubule associated protein 2 Get druggable targets OG5_133504 All targets in OG5_133504
Schistosoma mansoni microtubule-associated protein tau Get druggable targets OG5_133504 All targets in OG5_133504
Schistosoma japonicum expressed protein Get druggable targets OG5_127917 All targets in OG5_127917
Echinococcus multilocularis microtubule associated protein 2 Get druggable targets OG5_133504 All targets in OG5_133504
Candida albicans one of two closely related potential jumonji-like transcription factor genes similar to S. cerevisiae RPH1 (YER169W) damage-resp Get druggable targets OG5_127917 All targets in OG5_127917
Echinococcus granulosus muscleblind protein Get druggable targets OG5_132352 All targets in OG5_132352
Loa Loa (eye worm) jmjC domain-containing protein Get druggable targets OG5_127917 All targets in OG5_127917
Candida albicans one of two closely related potential jumonji-like transcription factor genes similar to S. cerevisiae RPH1 (YER169W) damage-resp Get druggable targets OG5_127917 All targets in OG5_127917
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_127917 All targets in OG5_127917
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_132352 All targets in OG5_132352
Schistosoma mansoni jumonji domain containing protein Get druggable targets OG5_127917 All targets in OG5_127917
Trichomonas vaginalis set domain proteins, putative Get druggable targets OG5_131470 All targets in OG5_131470
Echinococcus multilocularis muscleblind protein 1 Get druggable targets OG5_132352 All targets in OG5_132352
Onchocerca volvulus Get druggable targets OG5_131470 All targets in OG5_131470
Echinococcus multilocularis jumonji domain containing protein Get druggable targets OG5_127917 All targets in OG5_127917
Echinococcus granulosus jumonji domain containing protein Get druggable targets OG5_127917 All targets in OG5_127917
Brugia malayi Pre-SET motif family protein Get druggable targets OG5_131470 All targets in OG5_131470
Brugia malayi Muscleblind-like protein Get druggable targets OG5_132352 All targets in OG5_132352
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_132352 All targets in OG5_132352
Schistosoma japonicum ko:K04380 microtubule-associated protein tau, putative Get druggable targets OG5_133504 All targets in OG5_133504
Echinococcus multilocularis muscleblind protein Get druggable targets OG5_132352 All targets in OG5_132352
Schistosoma japonicum Probable JmjC domain-containing histone demethylation protein 3B, putative Get druggable targets OG5_127917 All targets in OG5_127917
Schistosoma japonicum expressed protein Get druggable targets OG5_127917 All targets in OG5_127917
Loa Loa (eye worm) pre-SET domain-containing protein family protein Get druggable targets OG5_131470 All targets in OG5_131470
Schistosoma japonicum JmjC domain-containing histone demethylation protein 3C, putative Get druggable targets OG5_127917 All targets in OG5_127917
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Toxoplasma gondii histone lysine methyltransferase SET1 0.0065 0.04 0.2669
Echinococcus multilocularis aldo keto reductase 0.003 0.0148 0.0244
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0057 0.0344 0.0344
Plasmodium vivax endonuclease/exonuclease/phosphatase domain containing protein 0.0012 0.0008 0.0054
Onchocerca volvulus 0.0031 0.0154 0.0692
Onchocerca volvulus 0.003 0.0148 0.0663
Echinococcus multilocularis traf and tnf receptor associated protein 0.0012 0.0008 0.0013
Echinococcus granulosus aldo keto reductase family 1 member B4 0.003 0.0148 0.0244
Schistosoma mansoni hypothetical protein 0.0038 0.0203 0.0333
Brugia malayi jmjC domain containing protein 0.0044 0.0251 0.1289
Echinococcus granulosus neuropeptide receptor 0.001 0 0.0001
Echinococcus granulosus carbonic anhydrase II 0.0098 0.065 0.107
Brugia malayi hypothetical protein 0.001 0 0.0003
Echinococcus granulosus microtubule associated protein 2 0.0833 0.6075 1
Loa Loa (eye worm) hypothetical protein 0.003 0.0143 0.063
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0057 0.0344 0.1512
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0013 0.0018 0.0118
Echinococcus multilocularis muscleblind protein 1 0.018 0.1255 0.2065
Plasmodium falciparum inorganic anion exchanger, inorganic anion antiporter 0.0026 0.0117 0.3405
Entamoeba histolytica hypothetical protein 0.0061 0.0377 0.126
Trichomonas vaginalis aldo/keto reductase, putative 0.003 0.0148 0.0195
Leishmania major DNA polymerase eta, putative 0.0011 0.0002 0.0008
Echinococcus granulosus rhodopsin orphan GPCR 0.001 0 0.0001
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0014 0.0024 0.0039
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0012 0.0008 0.0054
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.003 0.0148 0.0195
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0033 0.0165 0.0271
Brugia malayi Nuclear hormone receptor-like 1 0.0012 0.0013 0.0068
Echinococcus granulosus traf and tnf receptor associated protein 0.0012 0.0008 0.0013
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0012 0.0008 0.0041
Echinococcus multilocularis mitogen activated protein kinase 3 0.0036 0.0191 0.0315
Loa Loa (eye worm) hypothetical protein 0.0011 0.0007 0.0031
Echinococcus granulosus synaptojanin 1 0.0012 0.0008 0.0013
Trichomonas vaginalis CMGC family protein kinase 0.0036 0.0191 0.0255
Loa Loa (eye worm) hypothetical protein 0.001 0 0.0002
Echinococcus granulosus aldo keto reductase family 1 member B4 0.003 0.0148 0.0244
Onchocerca volvulus Putative sulfate transporter 0.0165 0.1141 0.5129
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0012 0.0011 0.0077
Trichomonas vaginalis aldo-keto reductase, putative 0.003 0.0148 0.0195
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0011 0.0007 0.0011
Schistosoma mansoni carbon catabolite repressor protein 0.0012 0.0008 0.0013
Brugia malayi TAR-binding protein 0.012 0.0808 0.4155
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0089 0.0577 0.3845
Schistosoma mansoni hypothetical protein 0.0038 0.0203 0.0333
Echinococcus granulosus dna polymerase kappa 0.0035 0.0178 0.0294
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0058
Echinococcus multilocularis dna polymerase eta 0.0035 0.0178 0.0294
Loa Loa (eye worm) hypothetical protein 0.018 0.1255 0.5515
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0143 0.0956
Brugia malayi Cathepsin L-like precursor 0.0023 0.0095 0.0487
Plasmodium falciparum histone acetyltransferase GCN5 0.0043 0.0238 0.691
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.001 0 0.0001
Brugia malayi beta-lactamase 0.0214 0.15 0.7711
Echinococcus multilocularis neuropeptide Y receptor 0.001 0 0.0001
Leishmania major inositol phosphosphingolipid phospholipase C-Like 0.0012 0.0008 0.0027
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0036 0.0191 0.1274
Mycobacterium tuberculosis Conserved protein 0.0214 0.15 0.15
Onchocerca volvulus 0.0023 0.0095 0.0424
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0012 0.0011 0.0019
Plasmodium vivax vivapain-1 0.0012 0.0011 0.0077
Schistosoma mansoni hypothetical protein 0.001 0 0.0001
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0044 0.0245 0.078
Schistosoma mansoni DNA polymerase IV / kappa 0.0011 0.0002 0.0004
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0023 0.0095 0.0121
Schistosoma mansoni opsin-like receptor 0.001 0 0.0001
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0012 0.0011 0.0019
Brugia malayi AMP-binding enzyme family protein 0.0044 0.0245 0.1261
Mycobacterium ulcerans carbonic anhydrase 0.0408 0.2936 0.4079
Loa Loa (eye worm) hypothetical protein 0.0214 0.15 0.6594
Entamoeba histolytica cysteine protease, putative 0.0012 0.0011 0.0012
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0023 0.0095 0.0121
Loa Loa (eye worm) hypothetical protein 0.003 0.0148 0.065
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0013 0.0018 0.0118
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0013 0.0018 0.0018
Trypanosoma cruzi cysteine peptidase, putative 0.0023 0.0095 0.0631
Leishmania major cathepsin L-like protease 0.0023 0.0095 0.0322
Mycobacterium ulcerans acyl-CoA synthetase 0.0044 0.0245 0.0338
Echinococcus granulosus aldehyde reductase 0.0022 0.0083 0.0136
Schistosoma mansoni phosphatidylserine receptor 0.0011 0.0007 0.0011
Mycobacterium tuberculosis Probable esterase LipL 0.0214 0.15 0.15
Loa Loa (eye worm) hypothetical protein 0.0012 0.0008 0.0035
Plasmodium vivax vivapain-2 0.0023 0.0095 0.0631
Echinococcus granulosus aldo keto reductase family 1 member B4 0.003 0.0148 0.0244
Echinococcus granulosus orexin receptor type 2 0.001 0 0.0001
Echinococcus multilocularis rhodopsin orphan GPCR 0.001 0 0.0001
Schistosoma mansoni jumonji domain containing protein 0.0011 0.0007 0.0011
Brugia malayi intermediate filament protein 0.0068 0.0424 0.218
Leishmania major endonuclease/exonuclease protein-like protein 0.0012 0.0008 0.0027
Trypanosoma cruzi mitochondrial protein 99, putative 0.0012 0.0008 0.0054
Plasmodium vivax vivapain-3 0.0012 0.0011 0.0077
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0012 0.0008 0.0054
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0012 0.0008 0.0054
Trypanosoma brucei DNA polymerase kappa, putative 0.0011 0.0002 0.0016
Loa Loa (eye worm) hypothetical protein 0.0012 0.0008 0.0035
Echinococcus granulosus ecdysone induced protein 78C 0.0012 0.0013 0.0022
Trichomonas vaginalis DNA polymerase eta, putative 0.0035 0.0178 0.0237
Loa Loa (eye worm) hypothetical protein 0.001 0 0.0002
Echinococcus granulosus 7TM GPCR rhodopsin 0.001 0 0.0001
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.001 0 0.0001
Trypanosoma cruzi PAB1-binding protein , putative 0.003 0.0148 0.0985
Schistosoma mansoni acetyl-CoA synthetase 0.0013 0.0018 0.0029
Entamoeba histolytica cysteine proteinase, putative 0.0016 0.0038 0.0102
Loa Loa (eye worm) hypothetical protein 0.0016 0.0038 0.0167
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0022 0.0089 0.0456
Schistosoma mansoni jumonji/arid domain-containing protein 0.0044 0.0251 0.0413
Mycobacterium ulcerans acyl-CoA synthetase 0.0044 0.0245 0.0338
Loa Loa (eye worm) hypothetical protein 0.0044 0.0245 0.1079
Echinococcus granulosus PHD finger protein rhinoceros 0.0035 0.0183 0.0301
Plasmodium falciparum carbon catabolite repressor protein 4, putative 0.0012 0.0008 0.0234
Loa Loa (eye worm) hypothetical protein 0.001 0 0.0002
Brugia malayi Cathepsin L-like precursor 0.0023 0.0095 0.0487
Onchocerca volvulus 0.003 0.0148 0.0663
Echinococcus granulosus thyrotropin releasing hormone receptor 0.001 0 0.0001
Echinococcus multilocularis neuropeptide FF receptor 2 0.001 0 0.0001
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0013 0.0018 0.0021
Entamoeba histolytica cysteine protease, putative 0.0012 0.0011 0.0012
Toxoplasma gondii PHD-finger domain-containing protein 0.0035 0.0183 0.122
Leishmania major hypothetical protein, conserved 0.0011 0.0007 0.0024
Echinococcus multilocularis musashi 0.0068 0.0424 0.0698
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0046 0.0266 0.1775
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0012 0.0008 0.0035
Trypanosoma cruzi cysteine peptidase, putative 0.0089 0.0577 0.3845
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0012 0.0013 0.0022
Loa Loa (eye worm) hypothetical protein 0.001 0 0.0002
Giardia lamblia Aldose reductase 0.003 0.0148 0.4263
Echinococcus multilocularis orexin receptor type 2 0.001 0 0.0001
Trypanosoma brucei hypothetical protein, conserved 0.0011 0.0002 0.0016
Plasmodium vivax hypothetical protein, conserved 0.0012 0.0008 0.0054
Echinococcus multilocularis thyroid hormone receptor alpha 0.0012 0.0013 0.0022
Echinococcus granulosus GPCR family 2 0.0038 0.0203 0.0333
Echinococcus multilocularis rhodopsin orphan GPCR 0.001 0 0.0001
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0187 0.1303 0.2145
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0012 0.0008 0.0054
Mycobacterium ulcerans aldehyde dehydrogenase 0.007 0.0436 0.0603
Echinococcus granulosus neuropeptide receptor 0.001 0 0.0001
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0012 0.0013 0.0022
Schistosoma mansoni cript-related 0.0012 0.0008 0.0013
Echinococcus multilocularis neuropeptide s receptor 0.001 0 0.0001
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0022 0.0089 0.0456
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0013 0.0018 0.0018
Echinococcus multilocularis dna polymerase kappa 0.0035 0.0178 0.0294
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0012 0.0008 0.0013
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0035 0.0178 0.0784
Leishmania major hypothetical protein, conserved 0.0012 0.0008 0.0027
Brugia malayi steroid hormone receptor 0.0012 0.0013 0.0068
Brugia malayi hypothetical protein 0.001 0 0.0003
Echinococcus granulosus CCR4 NOT transcription complex subunit 6 0.0012 0.0008 0.0013
Schistosoma mansoni hypothetical protein 0.001 0 0.0001
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.004 0.0218 0.0358
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0013 0.0018 0.0018
Mycobacterium ulcerans esterase/lipase LipP 0.0214 0.15 0.2083
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0046 0.0266 0.1775
Schistosoma mansoni adenoreceptor 0.001 0 0.0001
Schistosoma mansoni opsin-like receptor 0.001 0 0.0001
Echinococcus multilocularis serotonin receptor 0.001 0 0.0001
Brugia malayi Melatonin receptor type 1A 0.001 0 0.0003
Plasmodium vivax hypothetical protein, conserved 0.0035 0.0183 0.122
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0014 0.0024 0.0039
Echinococcus granulosus aldo keto reductase family 1 member B4 0.003 0.0148 0.0244
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.004 0.0218 0.0358
Schistosoma mansoni alpha-1 adrenergic receptor 0.001 0 0.0001
Mycobacterium leprae Probable transmembrane transport protein 0.0191 0.133 0.4497
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0012 0.0008 0.0054
Mycobacterium ulcerans hypothetical protein 0.0214 0.15 0.2083
Brugia malayi PHD-finger family protein 0.0035 0.0183 0.0941
Schistosoma mansoni ap endonuclease 0.0057 0.0344 0.0566
Echinococcus granulosus rhodopsin orphan GPCR 0.001 0 0.0001
Echinococcus granulosus cathepsin l1 0.0016 0.0038 0.0062
Loa Loa (eye worm) hypothetical protein 0.0016 0.0038 0.0167
Brugia malayi Cathepsin L-like precursor 0.0016 0.0038 0.0195
Loa Loa (eye worm) hypothetical protein 0.001 0 0.0002
Mycobacterium ulcerans acyl-CoA synthetase 0.0013 0.0018 0.0021
Echinococcus granulosus histone lysine methyltransferase setb 0.004 0.0218 0.0358
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.001 0 0.0001
Echinococcus granulosus lamin 0.0068 0.0424 0.0698
Onchocerca volvulus 0.0012 0.0008 0.0034
Echinococcus multilocularis neuropeptides capa receptor 0.001 0 0.0001
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.001 0 0.0001
Loa Loa (eye worm) hypothetical protein 0.001 0 0.0002
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0036 0.0191 0.1274
Trichomonas vaginalis aldo-keto reductase, putative 0.003 0.0148 0.0195
Schistosoma mansoni hypothetical protein 0.0012 0.0008 0.0013
Echinococcus multilocularis fmrfamide receptor 0.001 0 0.0001
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0044 0.0245 0.0338
Entamoeba histolytica cysteine proteinase, putative 0.0023 0.0095 0.0296
Brugia malayi larval opioid receptor 0.001 0 0.0003
Echinococcus multilocularis neuropeptide Y receptor 0.001 0 0.0001
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0012 0.0013 0.0022
Echinococcus granulosus tm gpcr rhodopsin 0.001 0 0.0001
Loa Loa (eye worm) hypothetical protein 0.0068 0.0424 0.1864
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.001 0 0.0001
Schistosoma mansoni lamin 0.0068 0.0424 0.0698
Schistosoma mansoni cpg binding protein 0.0033 0.0168 0.0276
Onchocerca volvulus Cathepsin L homolog 0.0023 0.0095 0.0424
Schistosoma mansoni carbonic anhydrase-related 0.0022 0.0089 0.0146
Schistosoma mansoni amine GPCR 0.001 0 0.0001
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0057 0.0344 0.5
Echinococcus multilocularis ecdysone induced protein 78C 0.0012 0.0013 0.0022
Onchocerca volvulus 0.004 0.0218 0.0976
Echinococcus multilocularis sex peptide receptor 0.001 0 0.0001
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0035 0.0178 0.0294
Leishmania major aldehyde reductase, putative,oxidoreductase, putative 0.003 0.0148 0.0504
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0187 0.1303 0.2145
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0012 0.0008 0.0041
Brugia malayi putative neuropeptide receptor NPR1 0.001 0 0.0003
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.001 0 0.0002
Toxoplasma gondii cathepsin CPL 0.0023 0.0095 0.0631
Brugia malayi AMP-binding enzyme family protein 0.0044 0.0245 0.1261
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0098 0.065 0.4333
Mycobacterium tuberculosis Beta-carbonic anhydrase CanB 0.0209 0.1466 0.1466
Echinococcus multilocularis neuropeptide receptor 0.001 0 0.0001
Echinococcus granulosus g protein coupled receptor 0.001 0 0.0001
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0012 0.0013 0.0068
Loa Loa (eye worm) hypothetical protein 0.001 0 0.0002
Entamoeba histolytica cysteine protease, putative 0.0012 0.0011 0.0012
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0027 0.0123 0.0819
Toxoplasma gondii PHD-finger domain-containing protein 0.0035 0.0183 0.122
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0214 0.15 0.6594
Leishmania major cathepsin L-like protease 0.0089 0.0577 0.1965
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0035 0.0183 0.0301
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.001 0 0.0001
Plasmodium vivax ataxin-2 like protein, putative 0.003 0.0148 0.0985
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.001 0 0.0001
Loa Loa (eye worm) hypothetical protein 0.001 0 0.0002
Schistosoma mansoni neuropeptide receptor 0.001 0 0.0001
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0046 0.0266 0.1775
Leishmania major 4-coumarate:coa ligase-like protein 0.0044 0.0245 0.0836
Echinococcus multilocularis lysine specific demethylase 6a 0.0011 0.0007 0.0011
Trypanosoma brucei inositol-1,4,5-trisphosphate (IP3) 5-phosphatase, putative 0.0012 0.0008 0.0054
Plasmodium falciparum phd finger protein, putative 0.0035 0.0183 0.532
Echinococcus granulosus beta LACTamase domain containing family member 0.0214 0.15 0.247
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0033 0.0164 0.0225
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0012 0.0013 0.0068
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.001 0 0.0001
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.012 0.0806 0.4144
Echinococcus multilocularis aldo keto reductase 0.003 0.0148 0.0244
Echinococcus granulosus biogenic amine 5HT receptor 0.001 0 0.0001
Schistosoma mansoni rhodopsin-like orphan GPCR 0.001 0 0.0001
Echinococcus multilocularis carbonic anhydrase II 0.0098 0.065 0.107
Echinococcus granulosus hypothetical protein 0.003 0.0148 0.0244
Loa Loa (eye worm) hypothetical protein 0.001 0 0.0002
Schistosoma mansoni hypothetical protein 0.0022 0.0089 0.0146
Echinococcus granulosus aldo keto reductase 0.003 0.0148 0.0244
Trichomonas vaginalis importin beta-1, putative 0.0024 0.0102 0.013
Brugia malayi polk-prov protein 0.0011 0.0002 0.0012
Echinococcus multilocularis PHD finger protein rhinoceros 0.0035 0.0183 0.0301
Echinococcus granulosus histone acetyltransferase KAT2B 0.0154 0.1057 0.1741
Mycobacterium tuberculosis Conserved hypothetical protein 0.0035 0.0178 0.0178
Mycobacterium ulcerans acyl-CoA synthetase 0.0044 0.0245 0.0338
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0012 0.0013 0.0022
Mycobacterium leprae CARBONIC ANHYDRASE (CARBONATE DEHYDRATASE) (CARBONIC DEHYDRATASE) 0.0408 0.2936 1
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0274 0.1946 0.8552
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.001 0 0.0003
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0058
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0023 0.0095 0.0121
Onchocerca volvulus 0.0312 0.2224 1
Echinococcus multilocularis g protein coupled receptor 0.001 0 0.0001
Schistosoma mansoni intracisternal A-particle retropepsin (A02 family) 0.0784 0.5714 0.9405
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.003 0.0148 0.0244
Mycobacterium ulcerans oxidoreductase 0.003 0.0148 0.0203
Loa Loa (eye worm) hypothetical protein 0.001 0 0.0002
Trypanosoma cruzi Inositol phosphosphingolipids phospholipase C 0.0012 0.0008 0.0054
Trypanosoma brucei aldo-keto reductase, putative 0.003 0.0148 0.0986
Brugia malayi F/Y-rich N-terminus family protein 0.0023 0.0089 0.0459
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.003 0.0148 0.0244
Trypanosoma brucei prostaglandin f synthase 0.003 0.0148 0.0986
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0038 0.0042
Trypanosoma brucei DNA polymerase kappa, putative 0.0024 0.0099 0.0661
Echinococcus multilocularis g protein coupled receptor 0.001 0 0.0001
Plasmodium falciparum carbon catabolite repressor protein 4, putative 0.0012 0.0008 0.0234
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0012 0.0013 0.0058
Brugia malayi jmjC domain containing protein 0.0115 0.0774 0.398
Loa Loa (eye worm) hypothetical protein 0.0032 0.0156 0.0684
Trypanosoma brucei DNA polymerase kappa, putative 0.0024 0.0099 0.0661
Entamoeba histolytica acyl-CoA synthetase, putative 0.0044 0.0245 0.0811
Giardia lamblia Inositol 5-phosphatase 4 0.0012 0.0008 0.0168
Leishmania major hypothetical protein, conserved 0.003 0.0148 0.0503
Onchocerca volvulus 0.0023 0.0095 0.0424
Trypanosoma cruzi hypothetical protein, conserved 0.0011 0.0002 0.0016
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0022 0.0089 0.0456
Brugia malayi AMP-binding enzyme family protein 0.0013 0.0018 0.0091
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0057 0.0344 0.2293
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0012 0.0013 0.0058
Entamoeba histolytica cysteine protease, putative 0.0012 0.0011 0.0012
Toxoplasma gondii hypothetical protein 0.0031 0.0152 0.1015
Schistosoma mansoni tar DNA-binding protein 0.012 0.0808 0.1331
Trypanosoma brucei DNA polymerase kappa, putative 0.0035 0.0178 0.1189
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0061 0.0377 0.0621
Brugia malayi Pre-SET motif family protein 0.0274 0.1946 1
Plasmodium vivax endonuclease/exonuclease/phosphatase domain containing protein 0.0012 0.0008 0.0054
Onchocerca volvulus 0.0013 0.0018 0.0078
Giardia lamblia Kinase, CMGC MAPK 0.0036 0.0191 0.5527
Entamoeba histolytica acetyltransferase, GNAT family 0.0043 0.0238 0.0784
Entamoeba histolytica cysteine proteinase, putative 0.0012 0.0011 0.0012
Entamoeba histolytica hypothetical protein 0.0061 0.0377 0.126
Schistosoma mansoni thyroid hormone receptor 0.0012 0.0013 0.0022
Entamoeba histolytica cysteine protease, putative 0.0012 0.0011 0.0012
Echinococcus granulosus snurportin 1 0.0319 0.2275 0.3745
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0058
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0023 0.0095 0.0121
Trichomonas vaginalis aldo-keto reductase, putative 0.003 0.0148 0.0195
Trypanosoma brucei inositol/phosphatidylinositol phosphatase, putative 0.0012 0.0008 0.0054
Echinococcus granulosus mitogen activated protein kinase 0.0036 0.0191 0.0315
Trichomonas vaginalis set domain proteins, putative 0.0312 0.2224 0.3084
Trichomonas vaginalis aldo-keto reductase, putative 0.003 0.0148 0.0195
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0012 0.0013 0.0057
Schistosoma mansoni neuropeptide receptor 0.001 0 0.0001
Loa Loa (eye worm) hypothetical protein 0.001 0 0.0002
Trichomonas vaginalis ap endonuclease, putative 0.0057 0.0344 0.0467
Plasmodium vivax hypothetical protein, conserved 0.0214 0.15 1
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0061 0.0377 0.0621
Schistosoma mansoni rhodopsin-like orphan GPCR 0.001 0 0.0001
Schistosoma mansoni biogenic amine (dopamine) receptor 0.001 0 0.0001
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.001 0 0.0002
Mycobacterium ulcerans acyl-CoA synthetase 0.0013 0.0018 0.0021
Entamoeba histolytica cysteine protease, putative 0.0012 0.0011 0.0012
Loa Loa (eye worm) hypothetical protein 0.001 0 0.0002
Entamoeba histolytica cysteine protease, putative 0.0012 0.0011 0.0012
Brugia malayi AKH receptor 0.001 0 0.0003
Plasmodium falciparum endonuclease/exonuclease/phosphatase family protein, putative 0.0012 0.0008 0.0234
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.003 0.0148 0.0244
Loa Loa (eye worm) jmjC domain-containing protein 0.0011 0.0007 0.0031
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0066 0.0409 0.1796
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.003 0.0148 0.0195
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0013 0.0018 0.0118
Leishmania major cathepsin L-like protease 0.0023 0.0095 0.0322
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0012 0.0008 0.0054
Trichomonas vaginalis D-aminoacylase, putative 0.0214 0.15 0.2076
Loa Loa (eye worm) hypothetical protein 0.001 0 0.0002
Loa Loa (eye worm) hypothetical protein 0.001 0 0.0002
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0012 0.0008 0.0054
Onchocerca volvulus 0.0214 0.15 0.6744
Echinococcus granulosus peregrin 0.0039 0.0212 0.0348
Brugia malayi Papain family cysteine protease containing protein 0.0023 0.0095 0.0487
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0066 0.0409 0.0673
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0058
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0012 0.0013 0.0068
Trypanosoma brucei DNA polymerase kappa, putative 0.0035 0.0178 0.1189
Schistosoma mansoni tar DNA-binding protein 0.012 0.0808 0.1331
Schistosoma mansoni neutral sphingomyelinase 0.0012 0.0008 0.0013
Loa Loa (eye worm) hypothetical protein 0.003 0.0148 0.065
Onchocerca volvulus 0.003 0.0148 0.0663
Loa Loa (eye worm) G-protein coupled receptor 0.001 0 0.0002
Echinococcus multilocularis neuropeptides capa receptor 0.001 0 0.0001
Leishmania major carbonic anhydrase-like protein 0.0098 0.065 0.2214
Trichomonas vaginalis conserved hypothetical protein 0.0985 0.7195 1
Echinococcus granulosus cpg binding protein 0.0033 0.0168 0.0276
Brugia malayi RNA, U transporter 1 0.0085 0.055 0.2825
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0013 0.0018 0.0078
Trypanosoma cruzi DNA damage repair protein, putative 0.0011 0.0002 0.0016
Echinococcus multilocularis cathepsin L 0.0012 0.0011 0.0019
Trichomonas vaginalis CMGC family protein kinase 0.0036 0.0191 0.0255
Loa Loa (eye worm) hypothetical protein 0.001 0 0.0002
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0013 0.0018 0.0021
Loa Loa (eye worm) fibroinase 0.0023 0.0095 0.0416
Onchocerca volvulus Protein ultraspiracle homolog 0.0012 0.0013 0.0057
Loa Loa (eye worm) oxidoreductase 0.003 0.0148 0.065
Brugia malayi AMP-binding enzyme family protein 0.0013 0.0018 0.0091
Trypanosoma cruzi cysteine peptidase, putative 0.0012 0.0011 0.0077
Loa Loa (eye worm) hypothetical protein 0.0011 0.0002 0.001
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0066 0.0409 0.21
Mycobacterium tuberculosis Probable lipase LipE 0.0214 0.15 0.15
Echinococcus granulosus alpha 1A adrenergic receptor 0.001 0 0.0001
Brugia malayi sulfakinin receptor protein 0.001 0 0.0003
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0098 0.065 0.2857
Echinococcus multilocularis importin subunit beta 1 0.003 0.0143 0.0236
Schistosoma mansoni steroid hormone receptor ad4bp 0.0012 0.0013 0.0022
Leishmania major cathepsin L-like protease 0.0089 0.0577 0.1965
Trichomonas vaginalis esterase, putative 0.0214 0.15 0.2076
Trypanosoma cruzi DNA damage repair protein, putative 0.0011 0.0002 0.0016
Schistosoma mansoni RAR-like nuclear receptor 0.0012 0.0013 0.0022
Trypanosoma brucei DNA damage repair protein, putative 0.0011 0.0002 0.0016
Schistosoma mansoni ocrl type II inositol 5-phosphatase 0.0012 0.0008 0.0013
Trichomonas vaginalis D-aminoacylase, putative 0.0214 0.15 0.2076
Brugia malayi hypothetical protein 0.001 0 0.0003
Echinococcus granulosus muscleblind protein 0.018 0.1255 0.2065
Mycobacterium ulcerans beta-lactamase 0.0214 0.15 0.2083
Loa Loa (eye worm) hypothetical protein 0.018 0.1255 0.5515
Schistosoma mansoni histamine h1 receptor 0.001 0 0.0001
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0192 0.1344 0.8956
Loa Loa (eye worm) ctsf protein 0.0023 0.0095 0.0416
Trypanosoma cruzi cysteine protease, putative 0.0012 0.0011 0.0077
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.003 0.0148 0.0244
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.007 0.0436 0.0436
Trichomonas vaginalis penicillin-binding protein, putative 0.0214 0.15 0.2076
Echinococcus multilocularis G protein coupled receptor 139 0.001 0 0.0001
Leishmania major hypothetical protein, conserved 0.0012 0.0008 0.0027
Loa Loa (eye worm) hypothetical protein 0.001 0 0.0002
Brugia malayi RNA recognition motif domain containing protein 0.012 0.0808 0.4155
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0319 0.2275 1
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0012 0.0013 0.0022
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0098 0.065 0.107
Trypanosoma brucei DNA polymerase kappa, putative 0.0035 0.0178 0.1189
Echinococcus granulosus mitogen activated protein kinase 3 0.0036 0.0191 0.0315
Schistosoma mansoni growth hormone secretagogue receptor 0.001 0 0.0001
Brugia malayi Serotonin/octopamine receptor family protein 7 0.001 0 0.0003
Trypanosoma cruzi hypothetical protein, conserved 0.0011 0.0002 0.0016
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.001 0 0.0001
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0013 0.0018 0.0091
Toxoplasma gondii hypothetical protein 0.0022 0.0089 0.0592
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0012 0.0008 0.0054
Echinococcus multilocularis CCR4 NOT transcription complex subunit 6 0.0012 0.0008 0.0013
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0023 0.0095 0.0121
Trichomonas vaginalis aldo-keto reductase, putative 0.003 0.0148 0.0195
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0013 0.0018 0.0018
Leishmania major aldo-keto reductase-like protein 0.003 0.0148 0.0504
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0012 0.0013 0.0068
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0214 0.15 0.247
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0158 0.109 0.1795
Treponema pallidum exodeoxyribonuclease (exoA) 0.0057 0.0344 1
Brugia malayi MH2 domain containing protein 0.0079 0.0504 0.2592
Echinococcus multilocularis lamin dm0 0.0068 0.0424 0.0698
Echinococcus multilocularis muscleblind protein 0.018 0.1255 0.2065
Trypanosoma cruzi cruzipain precursor, putative 0.0089 0.0577 0.3845
Brugia malayi ImpB/MucB/SamB family protein 0.0035 0.0178 0.0917
Schistosoma mansoni neuropeptide F-like receptor 0.001 0 0.0001
Trichomonas vaginalis antibiotic synthetase, putative 0.0013 0.0018 0.0013
Mycobacterium ulcerans hypothetical protein 0.0044 0.0245 0.0338
Schistosoma mansoni carbonic anhydrase 0.0022 0.0089 0.0146
Leishmania major acetyl-CoA synthetase, putative 0.0013 0.0018 0.006
Loa Loa (eye worm) hypothetical protein 0.0011 0.0007 0.0031
Loa Loa (eye worm) G-protein coupled receptor 0.001 0 0.0002
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0081 0.052 0.3467
Brugia malayi AF-10 protein 0.0012 0.0008 0.0041
Echinococcus multilocularis cathepsin L cysteine protease 0.0023 0.0095 0.0156
Echinococcus multilocularis carbonic anhydrase 0.0022 0.0089 0.0146
Trypanosoma cruzi hypothetical protein, conserved 0.0214 0.15 1
Loa Loa (eye worm) hypothetical protein 0.001 0 0.0002
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0057 0.0344 0.1147
Trypanosoma brucei DNA polymerase IV, putative 0.0035 0.0178 0.1189
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.001 0 0.0001
Schistosoma mansoni rhodopsin-like orphan GPCR 0.001 0 0.0001
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0057 0.0344 0.0566
Schistosoma mansoni cathepsin F (C01 family) 0.0023 0.0095 0.0156
Loa Loa (eye worm) hypothetical protein 0.0214 0.15 0.6594
Schistosoma mansoni tar DNA-binding protein 0.012 0.0808 0.1331
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0023 0.0095 0.0121
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0013 0.0018 0.0029
Echinococcus granulosus dro:myosuppressin receptor 0.001 0 0.0001
Echinococcus multilocularis inositol polyphosphate 5 phosphatase OCRL 1 0.0012 0.0008 0.0013
Trypanosoma cruzi cysteine peptidase, putative 0.0089 0.0577 0.3845
Trypanosoma brucei DNA polymerase kappa, putative 0.0035 0.0178 0.1189
Brugia malayi beta-lactamase family protein 0.0214 0.15 0.7711
Loa Loa (eye worm) hypothetical protein 0.0032 0.0156 0.0684
Loa Loa (eye worm) jmjC domain-containing protein 0.0011 0.0007 0.0031
Schistosoma mansoni cellular tumor antigen P53 0.0038 0.0201 0.0331
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0057 0.0344 1
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.001 0 0.0001
Brugia malayi Intermediate filament tail domain containing protein 0.0068 0.0424 0.218
Brugia malayi Dopamine receptor 0.001 0 0.0003
Entamoeba histolytica cysteine proteinase, putative 0.0023 0.0095 0.0296
Schistosoma mansoni synaptojanin 0.0012 0.0008 0.0013
Echinococcus multilocularis rhodopsin orphan GPCR 0.001 0 0.0001
Loa Loa (eye worm) hypothetical protein 0.001 0 0.0002
Echinococcus multilocularis GPCR, family 2 0.0038 0.0203 0.0333
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0012 0.0008 0.0041
Echinococcus granulosus neuropeptide receptor A26 0.001 0 0.0001
Echinococcus multilocularis beta LACTamase domain containing family member 0.0214 0.15 0.247
Mycobacterium tuberculosis Conserved hypothetical protein 0.0101 0.0671 0.0671
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0012 0.0008 0.0035
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0013 0.0018 0.0078
Brugia malayi hypothetical protein 0.002 0.0068 0.035
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.001 0 0.0001
Loa Loa (eye worm) neuropeptide F receptor 0.001 0 0.0002
Trypanosoma brucei DNA polymerase IV, putative 0.0035 0.0178 0.1189
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0012 0.0008 0.0035
Echinococcus multilocularis JmjC domain containing protein 4 0.0011 0.0007 0.0011
Schistosoma mansoni jumonji/arid domain-containing protein 0.0044 0.0251 0.0413
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0036 0.0191 0.1274
Schistosoma mansoni rhodopsin-like orphan GPCR 0.001 0 0.0001
Echinococcus granulosus importin subunit beta 1 0.003 0.0143 0.0236
Loa Loa (eye worm) hypothetical protein 0.0022 0.0089 0.039
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0013 0.0018 0.0118
Mycobacterium tuberculosis Conserved protein 0.0214 0.15 0.15
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.007 0.0436 0.1486
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0214 0.15 0.15
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.003 0.0148 0.0195
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0021 0.0076 0.0125
Onchocerca volvulus 0.0023 0.0095 0.0424
Trypanosoma cruzi aldo-keto reductase 0.003 0.0148 0.0986
Mycobacterium ulcerans aldehyde dehydrogenase 0.007 0.0436 0.0603
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0089 0.0577 0.3845
Schistosoma mansoni rhodopsin-like orphan GPCR 0.001 0 0.0001
Schistosoma mansoni family A2 unassigned peptidase (A02 family) 0.0143 0.0976 0.1606
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0012 0.0013 0.0022
Echinococcus granulosus tumor protein p63 0.0258 0.1824 0.3003
Loa Loa (eye worm) jmjC domain-containing protein 0.0073 0.046 0.2021
Echinococcus multilocularis rhodopsin orphan GPCR 0.001 0 0.0001
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0013 0.0018 0.0018
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0089 0.0577 0.3845
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0012 0.0008 0.0054
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0023 0.0095 0.0121
Onchocerca volvulus 0.0012 0.0013 0.0057
Echinococcus granulosus g protein coupled receptor 0.001 0 0.0001
Brugia malayi MAP kinase sur-1 0.0036 0.0191 0.0983
Echinococcus multilocularis tachykinin peptides receptor 99D 0.001 0 0.0001
Plasmodium falciparum JmjC domain-containing protein, putative 0.0011 0.0007 0.0203
Leishmania major carbonic anhydrase family protein, putative 0.0408 0.2936 1
Loa Loa (eye worm) oxidoreductase 0.0013 0.0018 0.0078
Echinococcus granulosus aldo keto reductase family 1 member B4 0.003 0.0148 0.0244
Trypanosoma cruzi cysteine proteinase, putative 0.0012 0.0011 0.0077
Trypanosoma brucei DNA polymerase eta, putative 0.0035 0.0178 0.1189
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0012 0.0013 0.0022
Echinococcus granulosus jumonji domain containing 1A 0.0011 0.0007 0.0011
Entamoeba histolytica cysteine proteinase, putative 0.0012 0.0011 0.0012
Schistosoma mansoni microtubule-associated protein tau 0.0833 0.6075 1
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0011 0.0007 0.0047
Giardia lamblia Histone acetyltransferase GCN5 0.0043 0.0238 0.6889
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0035 0.0178 0.0294
Echinococcus granulosus neuropeptide Y receptor 0.001 0 0.0001
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.003 0.0148 0.0244
Loa Loa (eye worm) hypothetical protein 0.001 0 0.0002
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0013 0.0018 0.0118
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.001 0 0.0001
Schistosoma mansoni synaptojanin 0.0012 0.0008 0.0013
Leishmania major DNA polymerase kappa, putative 0.0011 0.0002 0.0008
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0013 0.0018 0.0018
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0187 0.1303 0.2145
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0012 0.0008 0.0041
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.003 0.0148 0.0244
Brugia malayi hypothetical protein 0.001 0 0.0003
Trichomonas vaginalis aldo-keto reductase, putative 0.003 0.0148 0.0195
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0011 0.0005 0.0009
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0187 0.1303 0.2145
Brugia malayi neuropeptide F receptor 0.001 0 0.0003
Echinococcus granulosus serotonin receptor 0.001 0 0.0001
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0187 0.1303 0.2145
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0022 0.0089 0.0456
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0023 0.0095 0.2752
Schistosoma mansoni hypothetical protein 0.0014 0.0024 0.0039
Loa Loa (eye worm) hypothetical protein 0.0033 0.0164 0.072
Loa Loa (eye worm) hypothetical protein 0.0067 0.0415 0.1824
Schistosoma mansoni aldo-keto reductase 0.003 0.0148 0.0244
Loa Loa (eye worm) hypothetical protein 0.001 0 0.0002
Loa Loa (eye worm) jmjC domain-containing protein 0.0011 0.0007 0.0031
Toxoplasma gondii inorganic anion transporter, sulfate permease (SulP) family protein 0.0026 0.0117 0.0781
Onchocerca volvulus 0.0023 0.0095 0.0424
Entamoeba histolytica hypothetical protein 0.0024 0.0102 0.032
Loa Loa (eye worm) hypothetical protein 0.001 0 0.0002
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0012 0.0008 0.0041
Echinococcus granulosus FTZ F1 alpha 0.0012 0.0013 0.0022
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0011 0.0007 0.0047
Loa Loa (eye worm) hypothetical protein 0.001 0 0.0002
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.001 0 0.0003
Echinococcus granulosus jumonji domain containing protein 0.0049 0.0285 0.0469
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0023 0.0095 0.0121
Trypanosoma brucei Inositol phosphosphingolipids phospholipase C 0.0012 0.0008 0.0054
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0187 0.13 0.5843
Loa Loa (eye worm) hypothetical protein 0.0013 0.0021 0.0093
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0033 0.0164 1
Trichomonas vaginalis bromodomain-containing protein, putative 0.0046 0.0266 0.0359
Echinococcus granulosus tar DNA binding protein 0.012 0.0808 0.1331
Loa Loa (eye worm) hypothetical protein 0.001 0 0.0002
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0022 0.0089 0.039
Loa Loa (eye worm) hypothetical protein 0.0035 0.0183 0.0804
Loa Loa (eye worm) MH2 domain-containing protein 0.0079 0.0504 0.2216
Entamoeba histolytica cysteine proteinase, putative 0.0012 0.0011 0.0012
Onchocerca volvulus Cathepsin F homolog 0.0023 0.0095 0.0424
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0035 0.0178 0.0237
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.004 0.0218 0.0358
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.007 0.0436 0.0718
Loa Loa (eye worm) hypothetical protein 0.0044 0.0245 0.1079
Mycobacterium ulcerans acetyl-CoA synthetase 0.0013 0.0018 0.0021
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0013 0.0018 0.0021
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0214 0.15 0.7711
Echinococcus granulosus aldo keto reductase family 1 member B4 0.003 0.0148 0.0244
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0012 0.0008 0.0054
Trypanosoma brucei DNA polymerase kappa, putative 0.0011 0.0002 0.0016
Plasmodium falciparum importin beta, putative 0.003 0.0143 0.4169
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0012 0.0008 0.0054
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0012 0.0013 0.0022
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0023 0.0095 0.0121
Leishmania major cathepsin L-like protease 0.0023 0.0095 0.0322
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0035 0.0178 0.0294
Brugia malayi exodeoxyribonuclease III family protein 0.0057 0.0344 0.1768
Onchocerca volvulus 0.0038 0.0201 0.0903
Echinococcus multilocularis rhodopsin orphan GPCR 0.001 0 0.0001
Schistosoma mansoni neuropeptide receptor 0.001 0 0.0001
Loa Loa (eye worm) oxidoreductase 0.003 0.0148 0.065
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0013 0.0018 0.006
Toxoplasma gondii aldose reductase, putative 0.003 0.0148 0.0986
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0089 0.0577 0.3845
Loa Loa (eye worm) hypothetical protein 0.001 0 0.0002
Entamoeba histolytica cysteine proteinase, putative 0.0012 0.0011 0.0012
Schistosoma mansoni phd/f-box containing protein 0.0011 0.0007 0.0011
Loa Loa (eye worm) hypothetical protein 0.0082 0.0527 0.2315
Brugia malayi CCR4 0.0012 0.0008 0.0041
Echinococcus granulosus neutral sphingomyelinase 0.0012 0.0008 0.0013
Brugia malayi Papain family cysteine protease containing protein 0.0012 0.0011 0.0059
Schistosoma mansoni cpg binding protein 0.0033 0.0168 0.0276
Schistosoma mansoni neuropeptide receptor 0.001 0 0.0001
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0012 0.0008 0.0041
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0044 0.0245 0.0338
Loa Loa (eye worm) hypothetical protein 0.001 0 0.0002
Schistosoma mansoni hypothetical protein 0.0082 0.0527 0.0867
Trypanosoma cruzi pantothenate kinase subunit, putative 0.0013 0.0021 0.0141
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0013 0.0018 0.0033
Mycobacterium leprae Probable lipase LipE 0.0214 0.15 0.508
Schistosoma mansoni importin beta-1 0.003 0.0143 0.0236
Brugia malayi hypothetical protein 0.001 0 0.0003
Echinococcus multilocularis mitogen activated protein kinase 0.0036 0.0191 0.0315
Leishmania major cathepsin L-like protease 0.0023 0.0095 0.0322
Brugia malayi nuclear hormone receptor 0.0012 0.0013 0.0068
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0035 0.0178 0.0608
Loa Loa (eye worm) intermediate filament protein 0.0068 0.0424 0.1864
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0023 0.0095 0.0121
Mycobacterium tuberculosis Conserved protein 0.0214 0.15 0.15
Trichomonas vaginalis aldo/keto reductase, putative 0.003 0.0148 0.0195
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.0012 0.0008 0.0054
Loa Loa (eye worm) hypothetical protein 0.0214 0.15 0.6594
Echinococcus granulosus histone acetyltransferase KAT2B 0.0046 0.0266 0.0438
Echinococcus multilocularis g protein coupled receptor 0.001 0 0.0001
Brugia malayi nuclear receptor NHR-88 0.0012 0.0013 0.0068
Schistosoma mansoni biogenic amine (5HT) receptor 0.001 0 0.0001
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0038 0.0202 0.0332
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0012 0.0013 0.0058
Brugia malayi Cathepsin L-like cysteine proteinase 0.0016 0.0038 0.0195
Loa Loa (eye worm) hypothetical protein 0.001 0 0.0002
Plasmodium vivax sulfate transporter, putative 0.0026 0.0117 0.0781
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0214 0.15 0.2083
Plasmodium falciparum cysteine proteinase falcipain 3 0.0023 0.0095 0.2752
Onchocerca volvulus 0.0068 0.0424 0.1905
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0011 0.0002 0.0016
Entamoeba histolytica cysteine proteinase 1, putative 0.0012 0.0011 0.0012
Trypanosoma brucei DNA polymerase kappa, putative 0.0035 0.0178 0.1189
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0036 0.0191 0.1274
Echinococcus granulosus cathepsin l cysteine peptidase 0.0023 0.0095 0.0156
Echinococcus multilocularis rhodopsin orphan GPCR 0.001 0 0.0001
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0102 0.013
Trypanosoma cruzi DNA polymerase eta, putative 0.0011 0.0002 0.0016
Leishmania major pantothenate kinase subunit, putative 0.0013 0.0021 0.0072
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0012 0.0008 0.0041
Mycobacterium ulcerans acyl-CoA synthetase 0.0013 0.0018 0.0021
Trichomonas vaginalis antibiotic synthetase, putative 0.0013 0.0018 0.0013
Echinococcus multilocularis cathepsin L cysteine protease 0.0023 0.0095 0.0156
Echinococcus granulosus carbonic anhydrase 0.0022 0.0089 0.0146
Trichomonas vaginalis aldo-keto reductase, putative 0.003 0.0148 0.0195
Trichomonas vaginalis aldo/keto reductase, putative 0.003 0.0148 0.0195
Onchocerca volvulus 0.0016 0.0038 0.0168
Mycobacterium ulcerans DNA polymerase IV 0.0035 0.0178 0.0245
Leishmania major 4-coumarate:coa ligase-like protein 0.0044 0.0245 0.0836
Brugia malayi ORL1-like opioid receptor 0.001 0 0.0003
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0012 0.0013 0.0022
Echinococcus multilocularis microtubule associated protein 2 0.0833 0.6075 1
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.003 0.0148 0.0244
Entamoeba histolytica aldose reductase, putative 0.003 0.0148 0.0478
Mycobacterium ulcerans acyl-CoA synthetase 0.0013 0.0018 0.0021
Trypanosoma cruzi DNA polymerase eta, putative 0.0035 0.0178 0.1189
Entamoeba histolytica cysteine protease, putative 0.0012 0.0011 0.0012
Leishmania major hypothetical protein, conserved 0.0214 0.15 0.511
Brugia malayi jmjC domain containing protein 0.0011 0.0007 0.0036
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0027 0.0123 0.0819
Schistosoma mansoni cpg binding protein 0.0031 0.0154 0.0254
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0012 0.0013 0.0068
Trypanosoma cruzi mitochondrial protein 99, putative 0.0012 0.0008 0.0054
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0013 0.0018 0.0018
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0115 0.0774 0.1275
Echinococcus multilocularis snurportin 1 0.0319 0.2275 0.3745
Loa Loa (eye worm) hypothetical protein 0.0214 0.15 0.6594
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0091 0.0595 0.3968
Entamoeba histolytica acyl-CoA synthetase, putative 0.0044 0.0245 0.0811
Trypanosoma brucei PAB1-binding protein , putative 0.003 0.0148 0.0985
Plasmodium falciparum cysteine proteinase falcipain 1 0.0012 0.0011 0.0334
Brugia malayi Cathepsin L-like precursor 0.0023 0.0095 0.0487
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0012 0.0008 0.0041
Mycobacterium tuberculosis Probable exported protein 0.0012 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0033 0.0165 0.0725
Schistosoma mansoni biogenic amine (5HT) receptor 0.001 0 0.0001
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0038 0.0203 0.0333
Mycobacterium ulcerans acyl-CoA synthetase 0.0013 0.0018 0.0021
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0011 0.0007 0.0047
Echinococcus multilocularis neuropeptide receptor A26 0.001 0 0.0001
Loa Loa (eye worm) jmjC domain-containing protein 0.0044 0.0251 0.1103
Schistosoma mansoni hypothetical protein 0.0038 0.0203 0.0333
Schistosoma mansoni hypothetical protein 0.0061 0.0377 0.0621
Mycobacterium tuberculosis Probable oxidoreductase 0.003 0.0148 0.0148
Schistosoma mansoni coup transcription factor 0.0012 0.0013 0.0022
Mycobacterium ulcerans integral membrane transporter 0.0026 0.0117 0.016
Schistosoma mansoni serine/threonine protein kinase 0.0036 0.0191 0.0315
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0012 0.0013 0.0068
Trypanosoma cruzi cysteine peptidase, putative 0.0089 0.0577 0.3845
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0013 0.0018 0.0021
Loa Loa (eye worm) hypothetical protein 0.001 0 0.0002
Brugia malayi RNA binding protein 0.012 0.0808 0.4155
Entamoeba histolytica deoxycytidyl transferase, putative 0.0035 0.0178 0.0582
Trypanosoma brucei protein kinase, putative 0.0036 0.0191 0.1274
Echinococcus granulosus aldo keto reductase 0.003 0.0148 0.0244
Leishmania major mitochondrial DNA polymerase beta 0.0192 0.1344 0.4576
Toxoplasma gondii ABC1 family protein 0.0214 0.15 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0089 0.0577 0.3845
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0012 0.0013 0.0022
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0187 0.1303 0.2145
Mycobacterium ulcerans acyl-CoA synthetase 0.0013 0.0018 0.0021
Mycobacterium ulcerans DNA polymerase IV 0.0035 0.0178 0.0245
Brugia malayi Calcitonin receptor-like protein seb-1 0.012 0.0806 0.4144
Schistosoma mansoni jumonji domain containing protein 0.0092 0.0599 0.0987
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0012 0.0013 0.0058
Plasmodium vivax vivapain-2 0.0023 0.0095 0.0631
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0011 0.0007 0.0047
Brugia malayi photoreceptor-specific nuclear receptor 0.0012 0.0013 0.0068
Brugia malayi putative neuropeptide receptor 0.001 0 0.0003
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.001 0 0.0001
Schistosoma mansoni amine GPCR 0.001 0 0.0001
Plasmodium falciparum ataxin-2 like protein, putative 0.003 0.0148 0.4296
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0023 0.0095 0.0121
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0066 0.0409 0.0673
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0012 0.0008 0.0054
Trichomonas vaginalis aldo-keto reductase, putative 0.003 0.0148 0.0195
Schistosoma mansoni terminal deoxycytidyl transferase 0.0035 0.0178 0.0294
Echinococcus multilocularis carbonic anhydrase 0.0022 0.0089 0.0146
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0012 0.0013 0.0022
Loa Loa (eye worm) transcription factor SMAD2 0.0079 0.0504 0.2216
Echinococcus granulosus aldo keto reductase 0.003 0.0148 0.0244
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0013 0.0018 0.0029
Schistosoma mansoni amine GPCR 0.001 0 0.0001
Toxoplasma gondii LsmAD domain-containing protein 0.003 0.0148 0.0985
Trypanosoma brucei carbonic anhydrase-like protein 0.0098 0.065 0.4333
Echinococcus granulosus tm gpcr rhodopsin 0.001 0 0.0001
Schistosoma mansoni aldehyde dehydrogenase 0.007 0.0436 0.0718
Trichomonas vaginalis aldo-keto reductase, putative 0.003 0.0148 0.0195
Loa Loa (eye worm) steroid hormone receptor 0.0012 0.0013 0.0058
Giardia lamblia hypothetical protein 0.0012 0.0008 0.0168
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.003 0.0148 0.0244
Plasmodium vivax importin-beta 2, putative 0.003 0.0143 0.0956
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0013 0.0018 0.0018
Echinococcus granulosus cysteine protease 0.0012 0.0011 0.0019
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0012 0.0013 0.0058
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0012 0.0008 0.0035
Trichomonas vaginalis penicillin-binding protein, putative 0.0214 0.15 0.2076
Echinococcus granulosus cathepsin L cysteine proteinase 0.0023 0.0095 0.0156
Trypanosoma brucei DNA polymerase kappa, putative 0.0035 0.0178 0.1189
Brugia malayi Pre-SET motif family protein 0.004 0.0218 0.1118
Brugia malayi Cathepsin L-like precursor 0.0016 0.0038 0.0195
Loa Loa (eye worm) hypothetical protein 0.0093 0.0612 0.2692
Echinococcus granulosus cathepsin L cysteine protease 0.0012 0.0011 0.0019
Echinococcus granulosus rhodopsin orphan GPCR 0.001 0 0.0001
Onchocerca volvulus 0.0165 0.1141 0.5129
Schistosoma mansoni amine GPCR 0.001 0 0.0001
Schistosoma mansoni biogenic amine (dopamine) receptor 0.001 0 0.0001
Loa Loa (eye worm) histone methyltransferase 0.0011 0.0005 0.0023
Echinococcus granulosus intermediate filament protein 0.0068 0.0424 0.0698
Loa Loa (eye worm) hypothetical protein 0.0214 0.15 0.6594
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0038 0.0203 0.1041
Loa Loa (eye worm) hypothetical protein 0.001 0 0.0002
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0023 0.0095 0.0156
Schistosoma mansoni lamin 0.0068 0.0424 0.0698
Loa Loa (eye worm) hypothetical protein 0.0187 0.13 0.5713
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0068 0.0424 0.1864
Loa Loa (eye worm) hypothetical protein 0.001 0 0.0002
Onchocerca volvulus 0.003 0.0148 0.0663
Loa Loa (eye worm) hypothetical protein 0.0044 0.0245 0.1079
Brugia malayi acetyltransferase, GNAT family protein 0.0158 0.109 0.5603
Leishmania major acetyl-CoA synthetase, putative 0.0013 0.0018 0.006
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0033 0.0165 0.0271
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0023 0.0095 0.0121
Onchocerca volvulus 0.0013 0.0018 0.0078
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0089 0.0577 0.3845
Echinococcus granulosus G protein coupled receptor 139 0.001 0 0.0001
Echinococcus multilocularis rhodopsin orphan GPCR 0.001 0 0.0001
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0022 0.0089 0.0456
Leishmania major importin beta-1 subunit, putative 0.0024 0.0102 0.0347
Plasmodium falciparum acyl-CoA synthetase 0.0033 0.0164 0.4765
Trypanosoma brucei hypothetical protein, conserved 0.0214 0.15 1
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0158 0.109 0.1795
Loa Loa (eye worm) hypothetical protein 0.0016 0.0038 0.0167
Echinococcus granulosus 7tm_1 domain containing protein 0.001 0 0.0001
Schistosoma mansoni rhodopsin-like orphan GPCR 0.001 0 0.0001
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0012 0.0011 0.0077
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0036 0.0191 0.1274
Echinococcus granulosus rhodopsin orphan GPCR 0.001 0 0.0001
Onchocerca volvulus Cathepsin L homolog 0.0023 0.0095 0.0424
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.003 0.0148 0.0761
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0012 0.0013 0.0068
Brugia malayi gonadotropin-releasing hormone receptor 2 0.001 0 0.0003
Echinococcus granulosus rhodopsin orphan GPCR 0.001 0 0.0001
Echinococcus multilocularis G-protein coupled receptor, putative 0.001 0 0.0001
Schistosoma mansoni biogenic amine receptor 0.001 0 0.0001
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0044 0.0245 0.0245
Plasmodium vivax exodeoxyribonuclease III, putative 0.0012 0.0008 0.0054
Onchocerca volvulus Alhambra homolog 0.0035 0.0183 0.0821
Brugia malayi jmjC domain containing protein 0.0011 0.0007 0.0036
Brugia malayi ImpB/MucB/SamB family protein 0.0035 0.0178 0.0917
Brugia malayi follicle stimulating hormone receptor 0.001 0 0.0003
Echinococcus multilocularis aldo keto reductase 0.003 0.0148 0.0244
Brugia malayi G protein-coupled receptor F59B2.13 0.001 0 0.0003
Echinococcus granulosus neuropeptides capa receptor 0.001 0 0.0001
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0012 0.0013 0.0068
Echinococcus multilocularis cysteine protease 0.0023 0.0095 0.0156
Loa Loa (eye worm) hypothetical protein 0.001 0 0.0002
Trypanosoma cruzi Sulfate transporter N-terminal domain with GLY motif/Sulfate transporter family, putative 0.0026 0.0117 0.0781
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0143 0.0956
Mycobacterium leprae conserved hypothetical protein 0.0214 0.15 0.508
Loa Loa (eye worm) hypothetical protein 0.001 0 0.0002
Echinococcus multilocularis synaptojanin 1 0.0012 0.0008 0.0013
Leishmania major inositol/phosphatidylinositol phosphatase, putative 0.0012 0.0008 0.0027
Trypanosoma cruzi PAB1-binding protein , putative 0.003 0.0148 0.0985
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0023 0.0095 0.0121
Loa Loa (eye worm) hypothetical protein 0.0093 0.0612 0.2692
Schistosoma mansoni myosin xvIII 0.001 0 0.0001
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0013 0.0018 0.0118
Brugia malayi hypothetical protein 0.001 0 0.0003
Loa Loa (eye worm) hypothetical protein 0.001 0 0.0002
Schistosoma mansoni ap endonuclease 0.0057 0.0344 0.0566
Schistosoma mansoni hypothetical protein 0.0012 0.0008 0.0013
Onchocerca volvulus 0.0023 0.0095 0.0424
Loa Loa (eye worm) hypothetical protein 0.0022 0.0089 0.039
Brugia malayi RE15519p 0.001 0 0.0003
Loa Loa (eye worm) hypothetical protein 0.0038 0.0201 0.0885
Schistosoma mansoni nuclear hormone receptor 0.0012 0.0013 0.0022
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0089 0.0577 0.3845
Entamoeba histolytica aldose reductase, putative 0.003 0.0148 0.0478
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0012 0.0013 0.0022
Loa Loa (eye worm) hypothetical protein 0.004 0.0218 0.0956
Leishmania major cathepsin L-like protease 0.0023 0.0095 0.0322
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0115 0.0774 0.1275
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0057 0.0344 0.2293
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0038 0.0203 0.0333
Brugia malayi Cathepsin L-like precursor 0.0023 0.0095 0.0487
Plasmodium falciparum carbonic anhydrase 0.0022 0.0089 0.2582
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0046 0.0266 0.0359
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0013 0.002 0.0033
Echinococcus multilocularis cpg binding protein 0.0033 0.0168 0.0276
Brugia malayi Steroid receptor seven-up type 2 0.0012 0.0013 0.0068
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0031 0.0151 0.0151
Loa Loa (eye worm) follicle stimulating hormone receptor 0.001 0 0.0002
Brugia malayi PHD-finger family protein 0.0013 0.0021 0.0109
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0057 0.0344 0.2293
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0036 0.0191 0.0651
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0013 0.0018 0.0021
Plasmodium vivax hypothetical protein, conserved 0.0013 0.0022 0.0148
Echinococcus granulosus phd:f box containing protein 0.0011 0.0007 0.0011
Echinococcus multilocularis allatostatin A receptor 0.001 0 0.0001
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0057 0.0344 0.0475
Leishmania major cysteine peptidase A (CPA) 0.0023 0.0095 0.0322
Leishmania major prostaglandin f synthase, putative 0.003 0.0148 0.0504
Onchocerca volvulus Huntingtin homolog 0.0093 0.0612 0.2752
Schistosoma mansoni DNA polymerase eta 0.0035 0.0178 0.0294
Loa Loa (eye worm) hypothetical protein 0.0013 0.0018 0.0078
Echinococcus multilocularis tar DNA binding protein 0.012 0.0808 0.1331
Mycobacterium leprae Conserved hypothetical protein 0.0022 0.0083 0.0223
Loa Loa (eye worm) hypothetical protein 0.0012 0.0008 0.0035
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0044 0.0245 0.078
Leishmania major RNA-editing complex protein MP100, putative 0.0012 0.0008 0.0027
Loa Loa (eye worm) hypothetical protein 0.0033 0.0164 0.072
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0187 0.1303 0.2145
Plasmodium vivax acyl-CoA synthetase, putative 0.0033 0.0164 0.1093
Loa Loa (eye worm) cysteine protease 0.0023 0.0095 0.0416
Trichomonas vaginalis CMGC family protein kinase 0.0036 0.0191 0.0255
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0012 0.0011 0.0077
Brugia malayi ecdysteroid receptor 0.0012 0.0013 0.0068
Brugia malayi Importin beta-1 subunit 0.003 0.0143 0.0737
Schistosoma mansoni protein phosphatase 2C 0.0011 0.0007 0.0011
Brugia malayi hypothetical protein 0.003 0.0148 0.076
Brugia malayi N-terminal motif family protein 0.0187 0.13 0.6681
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0012 0.0008 0.0054
Brugia malayi GnHR receptor homolog 0.001 0 0.0003
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0023 0.0095 0.0121
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0027 0.0123 0.0819
Brugia malayi Serotonin receptor 0.001 0 0.0003
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.001 0 0.0001
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0023 0.0095 0.0121
Echinococcus granulosus neuropeptide s receptor 0.001 0 0.0001
Echinococcus granulosus geminin 0.0495 0.3578 0.589
Schistosoma mansoni tar DNA-binding protein 0.012 0.0808 0.1331
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0011 0.0002 0.0016
Echinococcus multilocularis cysteine protease 0.0023 0.0095 0.0156
Brugia malayi hypothetical protein 0.0061 0.0377 0.1938
Loa Loa (eye worm) hypothetical protein 0.0022 0.0089 0.039
Brugia malayi G-protein coupled receptor 0.001 0 0.0003
Brugia malayi neuropeptide F receptor 0.001 0 0.0003
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.001 0 0.0001
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0057 0.0344 0.2293
Trypanosoma brucei unspecified product 0.0024 0.0099 0.0661
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0011 0.0002 0.0016
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0031 0.0151 0.0151
Echinococcus multilocularis lamin 0.0068 0.0424 0.0698
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.0066 0.0409 0.0673
Echinococcus multilocularis jumonji domain containing protein 0.0049 0.0285 0.0469
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0068 0.0424 0.0698
Echinococcus granulosus carbonic anhydrase 0.0022 0.0089 0.0146
Brugia malayi hypothetical protein 0.001 0 0.0003
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0012 0.0013 0.0058
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0035 0.0178 0.0178
Brugia malayi CXXC zinc finger family protein 0.0031 0.0154 0.0793
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.003 0.0148 0.0761
Echinococcus granulosus biogenic amine 5HT receptor 0.001 0 0.0001
Schistosoma mansoni carbonic anhydrase 0.0408 0.2936 0.4833
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.001 0 0.0001
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0058
Mycobacterium ulcerans transmembrane carbonic anhydrase, SulP 0.0026 0.0117 0.016
Trypanosoma cruzi hypothetical protein, conserved 0.0214 0.15 1
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0091 0.0595 0.2028
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0102 0.013
Echinococcus multilocularis biogenic amine (5HT) receptor 0.001 0 0.0001
Mycobacterium ulcerans acyl-CoA synthetase 0.0013 0.0018 0.0021
Loa Loa (eye worm) hypothetical protein 0.012 0.0806 0.3544
Echinococcus granulosus allatostatin A receptor 0.001 0 0.0001
Trypanosoma brucei DNA polymerase kappa, putative 0.0035 0.0178 0.1189
Onchocerca volvulus Bile acid receptor homolog 0.0012 0.0013 0.0057
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0013 0.002 0.0033
Brugia malayi AMP-binding enzyme family protein 0.0044 0.0245 0.1261
Trichomonas vaginalis aldo-keto reductase, putative 0.003 0.0148 0.0195
Plasmodium falciparum DNA repair protein REV1, putative 0.0011 0.0002 0.0068
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.001 0 0.0002
Echinococcus multilocularis aldehyde reductase 0.0022 0.0083 0.0136
Echinococcus multilocularis somatostatin receptor 0.001 0 0.0001
Schistosoma mansoni hypothetical protein 0.0495 0.3578 0.589
Loa Loa (eye worm) hypothetical protein 0.0012 0.0008 0.0035
Trypanosoma brucei RNA editing exonuclease 2 0.0012 0.0008 0.0054
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0012 0.0008 0.0013
Echinococcus granulosus inositol polyphosphate 5 phosphatase OCRL 1 0.0012 0.0008 0.0013
Echinococcus granulosus neuropeptide Y receptor 0.001 0 0.0001
Loa Loa (eye worm) hypothetical protein 0.001 0 0.0002
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0058
Echinococcus granulosus aldo keto reductase family 1 member B4 0.003 0.0148 0.0244
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0012 0.0008 0.0054
Mycobacterium ulcerans acyl-CoA synthetase 0.0013 0.0018 0.0021
Plasmodium falciparum exodeoxyribonuclease III, putative 0.0012 0.0008 0.0234
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0023 0.0095 0.0121
Loa Loa (eye worm) hypothetical protein 0.001 0 0.0002
Leishmania major DNA damage repair protein, putative 0.0011 0.0002 0.0008
Echinococcus multilocularis FTZ F1 alpha 0.0012 0.0013 0.0022
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.001 0 0.0002
Trichomonas vaginalis aldo-keto reductase, putative 0.003 0.0148 0.0195
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0187 0.1303 0.6698
Schistosoma mansoni nocturnin 0.0012 0.0008 0.0013
Schistosoma mansoni aldo-keto reductase 0.003 0.0148 0.0244
Onchocerca volvulus 0.0023 0.0095 0.0424
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0023 0.0095 0.0416
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0187 0.1303 0.5728
Schistosoma mansoni rhodopsin-like orphan GPCR 0.001 0 0.0001
Echinococcus multilocularis alpha 1A adrenergic receptor 0.001 0 0.0001
Brugia malayi Cathepsin L-like precursor 0.0023 0.0095 0.0487
Schistosoma mansoni cathepsin F (C01 family) 0.0023 0.0095 0.0156
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0089 0.0577 0.3845
Plasmodium vivax acetyl-CoA synthetase, putative 0.0013 0.0018 0.0118
Onchocerca volvulus 0.0013 0.0018 0.0078
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.004 0.0218 0.0358
Schistosoma mansoni biogenic amine receptor 0.001 0 0.0001
Entamoeba histolytica cysteine protease, putative 0.0012 0.0011 0.0012
Trypanosoma brucei Sulfate transporter N-terminal domain with GLY motif/Sulfate transporter family, putative 0.0026 0.0117 0.0781
Loa Loa (eye worm) PHD-finger family protein 0.0035 0.0183 0.0804
Schistosoma mansoni neuropeptide f receptor 76f 0.001 0 0.0001
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0012 0.0013 0.0022
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0012 0.0013 0.0022
Schistosoma mansoni thyroid hormone receptor 0.0012 0.0013 0.0022
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.004 0.0218 0.0358
Echinococcus granulosus carbonic anhydrase 0.0022 0.0089 0.0146
Loa Loa (eye worm) hypothetical protein 0.0035 0.0178 0.0784
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0036 0.0191 0.0841
Trypanosoma cruzi DNA polymerase kappa, putative 0.0035 0.0178 0.1189
Schistosoma mansoni carbonic anhydrase-related 0.0022 0.0089 0.0146
Loa Loa (eye worm) neuropeptide F receptor 0.001 0 0.0002
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0027 0.0123 0.0819
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0098 0.065 0.107
Loa Loa (eye worm) hypothetical protein 0.0023 0.0095 0.0416
Loa Loa (eye worm) hypothetical protein 0.001 0 0.0002
Trypanosoma cruzi aldo/keto reductase, putative 0.003 0.0148 0.0986
Trypanosoma brucei unspecified product 0.0024 0.0099 0.0661
Leishmania major hypothetical protein, conserved 0.0012 0.0008 0.0027
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.001 0 0.0001
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0057 0.0344 0.0566
Trichomonas vaginalis CMGC family protein kinase 0.0036 0.0191 0.0255
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0098 0.065 0.3341
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0033 0.0167 0.111
Loa Loa (eye worm) hypothetical protein 0.001 0 0.0002
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.001 0 0.0001
Mycobacterium tuberculosis Probable transmembrane carbonic anhydrase (carbonate dehydratase) (carbonic dehydratase) 0.039 0.28 0.28
Echinococcus granulosus neuropeptides capa receptor 0.001 0 0.0001
Leishmania major DNA polymerase kappa, putative 0.0035 0.0178 0.0608
Leishmania major 4-coumarate:coa ligase-like protein 0.0044 0.0245 0.0836
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0011 0.0005 0.0005
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0044 0.0245 0.0338
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0066 0.0409 0.0673
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.001 0 0.0001
Trypanosoma cruzi Sulfate transporter N-terminal domain with GLY motif/Sulfate transporter family, putative 0.0026 0.0117 0.0781
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0012 0.0013 0.0022
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0089 0.0577 0.3845
Trypanosoma cruzi inositol 5-phosphatase 1, putative 0.0012 0.0008 0.0054
Loa Loa (eye worm) TAR-binding protein 0.012 0.0808 0.3553
Schistosoma mansoni retinoic acid receptor RXR 0.0012 0.0013 0.0022
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0058
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0012 0.0011 0.0005
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.003 0.0148 0.0244
Trypanosoma brucei DNA polymerase kappa, putative 0.0035 0.0178 0.1189
Brugia malayi Serotonin receptor 0.001 0 0.0003
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0023 0.0095 0.2752
Brugia malayi jmjC domain containing protein 0.0011 0.0007 0.0036
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0192 0.1344 0.8956
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0012 0.0008 0.0054
Brugia malayi cytoplasmic intermediate filament protein 0.0036 0.0191 0.0984
Schistosoma mansoni aldehyde dehydrogenase 0.007 0.0436 0.0718
Brugia malayi hypothetical protein 0.001 0 0.0003
Trypanosoma brucei unspecified product 0.0035 0.0178 0.1189
Echinococcus multilocularis tumor protein p63 0.0258 0.1824 0.3003
Loa Loa (eye worm) RNA binding protein 0.012 0.0808 0.3553
Leishmania major DNA polymerase eta, putative 0.0035 0.0178 0.0608
Trichomonas vaginalis ap endonuclease, putative 0.0057 0.0344 0.0467
Brugia malayi Bromodomain containing protein 0.0039 0.0212 0.1087
Echinococcus granulosus tachykinin peptides receptor 99D 0.001 0 0.0001
Loa Loa (eye worm) CXXC zinc finger family protein 0.0031 0.0154 0.0678
Brugia malayi Muscleblind-like protein 0.018 0.1255 0.6449
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.012 0.0808 0.3553
Loa Loa (eye worm) hypothetical protein 0.001 0 0.0002
Loa Loa (eye worm) hypothetical protein 0.0013 0.0018 0.0078
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0038 0.0203 0.0333
Brugia malayi hypothetical protein 0.0093 0.0612 0.3148
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0012 0.0013 0.0068
Trypanosoma brucei DNA polymerase kappa, putative 0.0035 0.0178 0.1189
Mycobacterium ulcerans carbonic anhydrase 0.0985 0.7195 1
Leishmania major prostaglandin f2-alpha synthase/D-arabinose dehydrogenase 0.003 0.0148 0.0504
Loa Loa (eye worm) hypothetical protein 0.001 0 0.0002
Entamoeba histolytica cysteine proteinase 2 0.0012 0.0011 0.0012
Loa Loa (eye worm) oxidoreductase 0.003 0.0148 0.065
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0012 0.0013 0.0068
Loa Loa (eye worm) hypothetical protein 0.001 0 0.0002
Loa Loa (eye worm) TYRA-2 protein 0.001 0 0.0002
Schistosoma mansoni rhodopsin-like orphan GPCR 0.001 0 0.0001
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0013 0.0018 0.0021
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0013 0.0018 0.0021
Mycobacterium ulcerans aldehyde dehydrogenase 0.007 0.0436 0.0603
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0036 0.0191 0.084
Leishmania major cathepsin L-like protease 0.0089 0.0577 0.1965
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0044 0.0245 0.0338
Echinococcus granulosus lamin dm0 0.0068 0.0424 0.0698
Echinococcus granulosus JmjC domain containing protein 4 0.0011 0.0007 0.0011
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0023 0.0095 0.0121
Onchocerca volvulus 0.0214 0.15 0.6744
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0013 0.0022 0.0644
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0013 0.0018 0.0021
Loa Loa (eye worm) CCR4-NOT transcription complex subunit 6 family protein 0.0012 0.0008 0.0035
Trichomonas vaginalis D-aminoacylase, putative 0.0214 0.15 0.2076
Toxoplasma gondii propionate-CoA ligase 0.0013 0.0018 0.0118
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0058
Echinococcus granulosus hypothetical protein 0.001 0 0.0001
Loa Loa (eye worm) melatonin receptor type 1A 0.001 0 0.0002
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0038 0.0042
Echinococcus granulosus lysine specific demethylase 6a 0.0011 0.0007 0.0011
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0012 0.0008 0.0054
Echinococcus multilocularis phd:f box containing protein 0.0011 0.0007 0.0011
Schistosoma mansoni cathepsin F (C01 family) 0.0016 0.0038 0.0062
Entamoeba histolytica hypothetical protein 0.0061 0.0377 0.126
Echinococcus multilocularis dro:myosuppressin receptor 0.001 0 0.0001
Loa Loa (eye worm) hypothetical protein 0.0033 0.0164 0.072
Trypanosoma cruzi importin beta-1 subunit, putative 0.0024 0.0102 0.0678
Trypanosoma brucei chrX additional, unordered contigs 0.0011 0.0002 0.0016
Brugia malayi Cathepsin L-like precursor 0.0023 0.0095 0.0487
Giardia lamblia PHD finger protein 15 0.0035 0.0183 0.5288
Onchocerca volvulus 0.003 0.0148 0.0663
Schistosoma mansoni transcription factor LCR-F1 0.0061 0.0377 0.0621
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0011 0.0007 0.0047
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0012 0.0013 0.0022
Echinococcus granulosus neuropeptide FF receptor 2 0.001 0 0.0001
Echinococcus granulosus aldo keto reductase family 1 member B4 0.003 0.0148 0.0244
Brugia malayi G-protein coupled receptor 0.001 0 0.0003
Entamoeba histolytica cysteine protease, putative 0.0012 0.0011 0.0012
Echinococcus multilocularis neutral sphingomyelinase 0.0012 0.0008 0.0013
Brugia malayi Dopamine receptor protein 1 0.001 0 0.0003
Onchocerca volvulus 0.0068 0.0424 0.1905
Entamoeba histolytica aldose reductase, putative 0.003 0.0148 0.0478
Echinococcus multilocularis carbonic anhydrase 0.0022 0.0089 0.0146
Echinococcus multilocularis serotonin receptor 0.001 0 0.0001
Toxoplasma gondii aldehyde dehydrogenase 0.007 0.0436 0.2908
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0012 0.0008 0.0054
Echinococcus multilocularis rhodopsin orphan GPCR 0.001 0 0.0001
Toxoplasma gondii PHD-finger domain-containing protein 0.0012 0.0008 0.0054
Entamoeba histolytica cysteine protease, putative 0.0023 0.0095 0.0296
Echinococcus granulosus cathepsin l1 0.0023 0.0095 0.0156
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.004 0.0218 0.145
Schistosoma mansoni hypothetical protein 0.0319 0.2275 0.3745
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0011 0.0005 0.0009
Brugia malayi hypothetical protein 0.001 0 0.0003
Schistosoma mansoni biogenic amine (dopamine) receptor 0.001 0 0.0001
Echinococcus granulosus sex peptide receptor 0.001 0 0.0001
Plasmodium falciparum DNase I-like protein, putative 0.0012 0.0008 0.0234
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0012 0.0013 0.0068
Mycobacterium tuberculosis Probable lipase LipD 0.0214 0.15 0.15
Onchocerca volvulus 0.0214 0.15 0.6744
Schistosoma mansoni biogenic amine receptor 0.001 0 0.0001
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0023 0.0095 0.0121
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0057 0.0344 1
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0044 0.0245 0.0245
Trypanosoma brucei DNA polymerase kappa, putative 0.0035 0.0178 0.1189
Loa Loa (eye worm) hypothetical protein 0.001 0 0.0002
Loa Loa (eye worm) hypothetical protein 0.001 0 0.0002
Loa Loa (eye worm) hypothetical protein 0.0214 0.15 0.6594
Echinococcus multilocularis neuropeptide receptor 0.001 0 0.0001
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0013 0.0018 0.0018
Loa Loa (eye worm) acetyltransferase 0.0158 0.109 0.4791
Entamoeba histolytica acyl-coA synthetase, putative 0.0044 0.0245 0.0811
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0012 0.0013 0.0022
Schistosoma mansoni rhodopsin-like orphan GPCR 0.001 0 0.0001
Entamoeba histolytica cysteine protease, putative 0.0012 0.0011 0.0012
Loa Loa (eye worm) hypothetical protein 0.001 0 0.0002
Echinococcus granulosus fmrfamide receptor 0.001 0 0.0001
Trypanosoma cruzi RNA-editing complex protein MP100, putative 0.0012 0.0008 0.0054
Mycobacterium leprae PROBABLE OXIDOREDUCTASE 0.003 0.0148 0.0446
Schistosoma mansoni intermediate filament proteins 0.0068 0.0424 0.0698
Brugia malayi Tachykinin-like peptides receptor 99D 0.001 0 0.0003
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.004 0.0218 0.0358
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0192 0.1344 0.8956
Trypanosoma brucei DNA-(apurinic or apyrimidinic site) lyase, putative 0.0012 0.0008 0.0054
Mycobacterium ulcerans transmembrane carbonic anhydrase, SulP 0.0026 0.0117 0.016
Mycobacterium tuberculosis Probable conserved transmembrane protein 0.0191 0.133 0.133
Trypanosoma brucei DNA polymerase kappa, putative 0.0024 0.0099 0.0661
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0036 0.0191 0.0651
Plasmodium falciparum ataxin-2 like protein, putative 0.003 0.0148 0.4296
Brugia malayi hypothetical protein 0.001 0 0.0003
Mycobacterium tuberculosis Probable hydrolase 0.0214 0.15 0.15
Echinococcus multilocularis jumonji domain containing 1A 0.0011 0.0007 0.0011
Schistosoma mansoni hypothetical protein 0.0035 0.0183 0.0301
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0013 0.0018 0.0018
Toxoplasma gondii exonuclease III APE 0.0057 0.0344 0.2293
Brugia malayi AMP-binding enzyme family protein 0.0013 0.0018 0.0091
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0031 0.0151 0.0151
Loa Loa (eye worm) beta-lactamase 0.0214 0.15 0.6594
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0013 0.0018 0.0515
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0012 0.0013 0.0058
Echinococcus granulosus somatostatin receptor 0.001 0 0.0001
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.001 0 0.0001
Plasmodium vivax unspecified product 0.0012 0.0011 0.0077
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0023 0.0095 0.0121
Onchocerca volvulus Putative neutral sphingomyelinase 0.0012 0.0008 0.0034
Echinococcus multilocularis geminin 0.0495 0.3578 0.589
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.001 0 0.0001
Onchocerca volvulus 0.0023 0.0095 0.0424
Echinococcus granulosus rhodopsin orphan GPCR 0.001 0 0.0001
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.001 0 0.0003
Onchocerca volvulus 0.0044 0.0245 0.1101
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0066 0.0409 0.0673
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0012 0.0013 0.0022
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.003 0.0148 0.0761
Echinococcus granulosus tm gpcr rhodopsin 0.001 0 0.0001
Brugia malayi Latrophilin receptor protein 2 0.0038 0.0203 0.1041
Schistosoma mansoni hypothetical protein 0.001 0 0.0001
Loa Loa (eye worm) hypothetical protein 0.001 0 0.0002
Brugia malayi latrophilin 2 splice variant baaae 0.0082 0.0527 0.2708
Schistosoma mansoni amine GPCR 0.001 0 0.0001
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0013 0.0018 0.0118
Giardia lamblia DINP protein human, muc B family 0.0035 0.0178 0.5153
Loa Loa (eye worm) carbonic anhydrase 3 0.0098 0.065 0.2857
Echinococcus granulosus cathepsin L 0.0012 0.0011 0.0019
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0057 0.0344 0.1172
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0023 0.0095 0.0156
Giardia lamblia Aldose reductase 0.003 0.0148 0.4263
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0012 0.0013 0.0022
Schistosoma mansoni tar DNA-binding protein 0.012 0.0808 0.1331
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.003 0.0148 0.0244
Schistosoma mansoni hypothetical protein 0.0038 0.0203 0.0333
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.001 0 0.0001
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0012 0.0008 0.0054
Echinococcus granulosus g protein coupled receptor 0.001 0 0.0001
Loa Loa (eye worm) oxidoreductase 0.003 0.0148 0.065
Echinococcus granulosus peptide allatostatin:somatostatin 0.001 0 0.0001
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.003 0.0148 0.0761
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.003 0.0148 0.0244
Trypanosoma cruzi DNA polymerase kappa, putative 0.0035 0.0178 0.1189
Brugia malayi cathepsin L-like precursor 0.0016 0.0038 0.0195
Entamoeba histolytica cysteine protease, putative 0.0012 0.0011 0.0012
Loa Loa (eye worm) hypothetical protein 0.0038 0.0203 0.089
Schistosoma mansoni opsin-like receptor 0.001 0 0.0001
Onchocerca volvulus 0.003 0.0148 0.0663
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0023 0.0095 0.0121
Schistosoma mansoni peptide (allatostatin)-like receptor 0.001 0 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.0985 0.7195 1
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.001 0 0.0001
Trypanosoma cruzi DNA polymerase kappa, putative 0.0035 0.0178 0.1189
Echinococcus multilocularis aldo keto reductase 0.003 0.0148 0.0244
Echinococcus granulosus lysine specific demethylase 5A 0.0044 0.0251 0.0413
Brugia malayi Papain family cysteine protease containing protein 0.0012 0.0011 0.0059
Onchocerca volvulus 0.0012 0.0008 0.0034
Echinococcus granulosus aldo keto reductase family 1 member B4 0.003 0.0148 0.0244
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0012 0.0011 0.0019
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0012 0.0008 0.0035
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0023 0.0095 0.0121
Brugia malayi jmjC domain containing protein 0.0011 0.0007 0.0036
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0013 0.0018 0.0091
Plasmodium vivax SET domain protein, putative 0.004 0.0218 0.145
Brugia malayi Dopamine receptor protein 2 0.001 0 0.0003
Echinococcus multilocularis fmrfamide receptor 0.001 0 0.0001
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0214 0.15 0.15
Loa Loa (eye worm) hypothetical protein 0.001 0 0.0002
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0214 0.15 0.15
Trichomonas vaginalis aldo-keto reductase, putative 0.003 0.0148 0.0195
Loa Loa (eye worm) oxidoreductase 0.003 0.0148 0.065
Echinococcus granulosus rhodopsin orphan GPCR 0.001 0 0.0001
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0012 0.0011 0.0005
Echinococcus multilocularis g-protein coupled receptor 0.001 0 0.0001
Schistosoma mansoni pol-related 0.003 0.0148 0.0244
Brugia malayi Putative carbonic anhydrase 5 precursor 0.0098 0.065 0.3341
Toxoplasma gondii HEAT repeat-containing protein 0.003 0.0143 0.0956
Schistosoma mansoni hypothetical protein 0.001 0 0.0001
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0013 0.0018 0.0018
Entamoeba histolytica cysteine protease, putative 0.0012 0.0011 0.0012
Entamoeba histolytica hypothetical protein 0.0061 0.0377 0.126
Brugia malayi G protein-coupled receptor 0.001 0 0.0003
Schistosoma mansoni carbonic anhydrase-related 0.0022 0.0089 0.0146
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0033 0.0164 0.0164
Trypanosoma cruzi cysteine proteinase, putative 0.0012 0.0011 0.0077
Onchocerca volvulus Huntingtin homolog 0.0093 0.0612 0.2752
Echinococcus granulosus g-protein coupled receptor 0.001 0 0.0001
Echinococcus granulosus dna polymerase eta 0.0035 0.0178 0.0294
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.007 0.0436 0.0718
Schistosoma mansoni neuropeptide F-like receptor 0.001 0 0.0001
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0012 0.0013 0.0068
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.001 0 0.0001
Trypanosoma brucei DNA polymerase IV, putative 0.0035 0.0178 0.1189
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0023 0.0095 0.0121
Brugia malayi beta-lactamase family protein 0.0214 0.15 0.7711
Mycobacterium ulcerans hypothetical protein 0.0101 0.0671 0.093
Echinococcus multilocularis lysine specific demethylase 5A 0.0043 0.0238 0.0391
Plasmodium vivax DNA repair protein REV1, putative 0.0011 0.0002 0.0016
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0089 0.0577 0.3845
Trypanosoma brucei hypothetical protein, conserved 0.0011 0.0002 0.0016
Mycobacterium ulcerans lipase LipD 0.0214 0.15 0.2083
Loa Loa (eye worm) hypothetical protein 0.0033 0.0164 0.072
Echinococcus multilocularis deoxyribonuclease 1 2 0.0012 0.0008 0.0013
Loa Loa (eye worm) hypothetical protein 0.0033 0.0164 0.072
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0091 0.0595 0.3968
Plasmodium vivax JmjC domain containing protein 0.0011 0.0007 0.0047
Trypanosoma cruzi endonuclease/exonuclease/phosphatase, putative 0.0012 0.0008 0.0054
Schistosoma mansoni hypothetical protein 0.0495 0.3578 0.589
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0012 0.0008 0.0054
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0012 0.0008 0.0041
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0013 0.0018 0.0118
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0214 0.15 0.247
Loa Loa (eye worm) hypothetical protein 0.001 0 0.0002
Loa Loa (eye worm) hypothetical protein 0.006 0.0369 0.162
Trypanosoma cruzi DNA polymerase kappa, putative 0.0035 0.0178 0.1189
Loa Loa (eye worm) latrophilin receptor protein 2 0.0038 0.0203 0.089
Brugia malayi AMP-binding enzyme family protein 0.0013 0.0018 0.0091
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0098 0.065 0.4333
Mycobacterium tuberculosis Beta-carbonic anhydrase 0.0786 0.5725 0.5725
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0023 0.0095 0.0121
Onchocerca volvulus 0.0013 0.0018 0.0078
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0031 0.0151 0.0151
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0012 0.0013 0.0068
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0023 0.0095 0.0121
Trypanosoma brucei DNA damage repair protein, putative 0.0011 0.0002 0.0016
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0038 0.0203 0.0333
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0023 0.0095 0.0416
Trypanosoma cruzi major cysteine proteinase, putative 0.007 0.0437 0.2912
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0023 0.0095 0.0121
Loa Loa (eye worm) pigment dispersing factor receptor c 0.012 0.0806 0.3544
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0089 0.0577 0.3845
Echinococcus multilocularis peregrin 0.0039 0.0212 0.0348
Entamoeba histolytica carbonic anhydrase, putative 0.0408 0.2936 1
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0036 0.0191 0.1274

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 3.5481 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504404] ChEMBL. No reference
Potency (functional) = 7.9433 um PUBCHEM_BIOASSAY: qHTS for inhibitors of ROR gamma transcriptional activity. (Class of assay: confirmatory) ChEMBL. No reference
Potency (binding) = 10 um PUBCHEM_BIOASSAY: qHTS for Inhibitors of Tau Fibril Formation, Thioflavin T Binding. (Class of assay: confirmatory) [Related pubchem assays: 596 ] ChEMBL. No reference
Potency (functional) 10 uM PubChem BioAssay. qHTS for Inhibitors of ATXN expression. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 15.8489 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of JMJD2A-Tudor Domain. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504402] ChEMBL. No reference
Potency (binding) 19.9526 uM PubChem BioAssay. qHTS Assay for Inhibitors of MBNL1-poly(CUG) RNA binding. (Class of assay: confirmatory) ChEMBL. No reference
Potency (binding) = 22.3872 um PUBCHEM_BIOASSAY: qHTS Assay for Identification of Novel General Anesthetics. In this assay, a GABAergic mimetic model system, apoferritin and a profluorescent 1-aminoanthracene ligand (1-AMA), was used to construct a competitive binding assay for identification of novel general anesthetics (Class of assay: confirmatory) [Related pubchem assays: 2385 (Probe Development Summary for Identification of Novel General Anesthetics), 2323 (Validation apoferritin assay run on SigmaAldrich LOPAC1280 collection)] ChEMBL. No reference
Potency (functional) 26.8545 uM PUBCHEM_BIOASSAY: qHTS profiling assay for firefly luciferase inhibitor/activator using purified enzyme and Km concentrations of substrates (counterscreen for miR-21 project). (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2288, AID2289, AID2598, AID411] ChEMBL. No reference
Potency (functional) 29.081 uM PUBCHEM_BIOASSAY: qHTS screen for small molecules that inhibit ELG1-dependent DNA repair in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493107, AID493125] ChEMBL. No reference
Potency (functional) 100 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Iota. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588623] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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