Detailed information for compound 1458800

Basic information

Technical information
  • TDR Targets ID: 1458800
  • Name: 2-[3-(3,4-dichlorophenyl)-6,7-dihydro-5H-pyrr olo[2,1-b]imidazol-1-ium-1-yl]-1-phenothiazin -10-ylethanone
  • MW: 493.428 | Formula: C26H20Cl2N3OS+
  • H donors: 0 H acceptors: 1 LogP: 6.31 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(N1c2ccccc2Sc2c1cccc2)C[n+]1cc(n2c1CCC2)c1ccc(c(c1)Cl)Cl
  • InChi: 1S/C26H20Cl2N3OS/c27-18-12-11-17(14-19(18)28)22-15-29(25-10-5-13-30(22)25)16-26(32)31-20-6-1-3-8-23(20)33-24-9-4-2-7-21(24)31/h1-4,6-9,11-12,14-15H,5,10,13,16H2/q+1
  • InChiKey: BONOZTUZIIWFQU-UHFFFAOYSA-N  

Network

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Synonyms

  • 2-[3-(3,4-dichlorophenyl)-6,7-dihydro-5H-pyrrolo[2,1-b]imidazol-1-ium-1-yl]-1-phenothiazin-10-yl-ethanone
  • 2-[3-(3,4-dichlorophenyl)-6,7-dihydro-5H-pyrrolo[2,1-b]imidazol-1-ium-1-yl]-1-(10-phenothiazinyl)ethanone
  • STOCK4S-43152

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Echinococcus multilocularis histone acetyltransferase MYST2 0.0066 0.0739 0.0737
Echinococcus multilocularis carbonic anhydrase 0.0438 0.5379 0.5379
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0123 0.0397
Echinococcus granulosus cathepsin l1 0.0016 0.0123 0.0121
Brugia malayi beta-lactamase family protein 0.0043 0.0464 0.0462
Schistosoma mansoni cathepsin F (C01 family) 0.0011 0.0057 0.0057
Loa Loa (eye worm) hypothetical protein 0.004 0.0417 0.0417
Schistosoma mansoni smad1 5 8 and 0.001 0.0044 0.0044
Trichomonas vaginalis malate dehydrogenase, putative 0.0255 0.3105 1
Leishmania major cytosolic malate dehydrogenase 0.0255 0.3105 0.3101
Echinococcus granulosus TRP transient receptor potential channel 0.0044 0.0465 0.0463
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0154 0.0224
Loa Loa (eye worm) hypothetical protein 0.0012 0.0074 0.0074
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0043 0.0464 0.1479
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0123 0.0349
Loa Loa (eye worm) hypothetical protein 0.0007 0.0006 0.0006
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0043 0.0464 0.0464
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0012 0.0071 0.0098
Plasmodium falciparum L-lactate dehydrogenase 0.054 0.6655 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0123 0.0397
Echinococcus multilocularis short transient receptor potential channel 6 0.0078 0.0888 0.0887
Onchocerca volvulus 0.0114 0.1341 0.4807
Toxoplasma gondii isocitrate dehydrogenase 0.0019 0.016 0.0232
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0231 0.2799 0.2798
Echinococcus granulosus polycomb protein SCMH1 0.0058 0.064 0.0638
Echinococcus granulosus L lactate dehydrogenase B chain 0.054 0.6655 0.6654
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0006 0 0.00000000019817
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.069 0.0685
Schistosoma mansoni smad 0.001 0.0044 0.0044
Loa Loa (eye worm) hypothetical protein 0.0017 0.0135 0.0135
Entamoeba histolytica malate dehydrogenase, putative 0.054 0.6655 1
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0808 1 1
Loa Loa (eye worm) hypothetical protein 0.0012 0.0074 0.0074
Plasmodium falciparum cysteine proteinase falcipain 3 0.0016 0.0123 0.0177
Entamoeba histolytica cysteine protease, putative 0.0008 0.0026 0.003
Brugia malayi Papain family cysteine protease containing protein 0.0008 0.0026 0.0024
Mycobacterium ulcerans beta-lactamase 0.0043 0.0464 0.1479
Brugia malayi isocitrate dehydrogenase 0.0019 0.016 0.0158
Echinococcus multilocularis lysosomal alpha glucosidase 0.0197 0.2375 0.2373
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0044 0.0465 0.0463
Loa Loa (eye worm) hypothetical protein 0.0017 0.0135 0.0135
Loa Loa (eye worm) hypothetical protein 0.0042 0.0447 0.0447
Echinococcus multilocularis lactate dehydrogenase protein 0.054 0.6655 0.6654
Loa Loa (eye worm) MBCTL1 0.0066 0.0739 0.0739
Echinococcus multilocularis malate dehydrogenase 0.0249 0.3023 0.3022
Echinococcus granulosus neuropeptide receptor A26 0.0448 0.5514 0.5513
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.001 0.0042 0.004
Loa Loa (eye worm) hypothetical protein 0.0043 0.0464 0.0464
Leishmania major cathepsin L-like protease 0.0062 0.069 0.0685
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0438 0.5379 0.5379
Schistosoma mansoni sex comb on midleg homolog 0.0058 0.064 0.064
Echinococcus multilocularis malate dehydrogenase 0.0249 0.3023 0.3022
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0012 0.0074 0.0074
Entamoeba histolytica cysteine proteinase, putative 0.0008 0.0026 0.003
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0012 0.0071 0.0098
Echinococcus granulosus cysteine protease 0.0008 0.0026 0.0024
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0016 0.0123 0.0123
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0012 0.0074 0.0074
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0123 0.0397
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0023 0.0207 0.0597
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0016 0.0124 0.0119
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0044 0.0466 0.0693
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0023 0.0207 0.0651
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0029 0.0289 0.0289
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0278 0.3386 1
Echinococcus granulosus mixed lineage leukemia protein mll 0.0008 0.0021 0.0019
Entamoeba histolytica cysteine proteinase, putative 0.0008 0.0026 0.003
Plasmodium vivax malate dehydrogenase, putative 0.054 0.6655 1
Giardia lamblia Malate dehydrogenase 0.0255 0.3105 1
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0019 0.016 0.0158
Trypanosoma cruzi ISWI complex protein 0.0017 0.0131 0.0126
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0154 0.0149
Loa Loa (eye worm) hypothetical protein 0.0012 0.0074 0.0074
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0438 0.5379 0.5379
Toxoplasma gondii ABC1 family protein 0.0043 0.0464 0.0689
Leishmania major malate dehydrogenase, putative 0.054 0.6655 0.6653
Plasmodium vivax lactate/malate dehydrogenase, putative 0.0231 0.2805 0.421
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0008 0.0026 0.002
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0123 0.0397
Trypanosoma cruzi cruzipain precursor, putative 0.0062 0.069 0.0685
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0011 0.0057 0.0182
Trichomonas vaginalis alpha-glucosidase, putative 0.0044 0.0466 0.1501
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0019 0.016 0.016
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0207 0.0651
Echinococcus granulosus lactate dehydrogenase a 0.054 0.6655 0.6654
Echinococcus multilocularis transient receptor potential ion channel A 0.0113 0.1335 0.1333
Trypanosoma brucei malate dehydrogenase-related 0.0231 0.2805 0.2801
Leishmania major cathepsin L-like protease 0.0062 0.069 0.0685
Plasmodium falciparum cysteine proteinase falcipain 1 0.0008 0.0026 0.003
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0154 0.0224
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0197 0.2375 0.2375
Echinococcus multilocularis carbonic anhydrase 0.0438 0.5379 0.5379
Brugia malayi Cathepsin L-like precursor 0.0011 0.0057 0.0055
Entamoeba histolytica hypothetical protein 0.0035 0.0357 0.0528
Trypanosoma cruzi hypothetical protein, conserved 0.0043 0.0464 0.0459
Schistosoma mansoni zinc finger protein 0.0023 0.0209 0.0209
Trypanosoma brucei mitochondrial malate dehydrogenase 0.0249 0.3023 0.3019
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0019 0.016 0.0158
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0019 0.0154 0.0197
Echinococcus multilocularis Smad4 0.001 0.0044 0.0042
Trichomonas vaginalis malate dehydrogenase, putative 0.0255 0.3105 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.069 0.0685
Leishmania major cathepsin L-like protease 0.0062 0.069 0.0685
Loa Loa (eye worm) hypothetical protein 0.0043 0.0464 0.0464
Echinococcus multilocularis cysteine protease 0.0016 0.0123 0.0121
Trypanosoma cruzi hypothetical protein, conserved 0.0043 0.0464 0.0459
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0123 0.0397
Loa Loa (eye worm) hypothetical protein 0.0012 0.0074 0.0074
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.069 0.0685
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0016 0.0124 0.0401
Brugia malayi Cathepsin L-like precursor 0.0016 0.0123 0.0121
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0016 0.0124 0.0179
Schistosoma mansoni ferritin light chain 0.0008 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.0044 0.0465 0.0465
Brugia malayi Bromodomain containing protein 0.0042 0.0446 0.0444
Entamoeba histolytica cysteine proteinase, putative 0.0016 0.0123 0.0177
Echinococcus granulosus zinc finger protein 0.0023 0.0209 0.0207
Schistosoma mansoni cpg binding protein 0.0031 0.0314 0.0314
Loa Loa (eye worm) steroid hormone receptor 0.0012 0.0074 0.0074
Brugia malayi AMP-binding enzyme family protein 0.0007 0.0006 0.0003
Echinococcus granulosus cathepsin L cysteine proteinase 0.0016 0.0123 0.0121
Trichomonas vaginalis antibiotic synthetase, putative 0.0007 0.0006 0.0018
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0207 0.0202
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0011 0.0057 0.0182
Echinococcus multilocularis carbonic anhydrase II 0.0808 1 1
Trichomonas vaginalis malate dehydrogenase, putative 0.0255 0.3105 1
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0019 0.016 0.0456
Loa Loa (eye worm) hypothetical protein 0.0438 0.5379 0.5379
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0012 0.0074 0.0074
Toxoplasma gondii malate dehydrogenase MDH 0.054 0.6655 1
Echinococcus granulosus cathepsin L cysteine protease 0.0008 0.0026 0.0024
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0019 0.016 0.0154
Echinococcus multilocularis zinc finger protein 0.0023 0.0209 0.0207
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0154 0.0154
Schistosoma mansoni smad1 5 8 and 0.001 0.0044 0.0044
Trichomonas vaginalis malate dehydrogenase, putative 0.0137 0.1626 0.5238
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0026 0.025 0.0248
Trichomonas vaginalis alpha-glucosidase, putative 0.0044 0.0466 0.1501
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0154 0.0497
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0019 0.0154 0.048
Mycobacterium tuberculosis Probable esterase LipL 0.0043 0.0464 0.1356
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0207 0.0202
Loa Loa (eye worm) MH2 domain-containing protein 0.0144 0.1719 0.1719
Echinococcus multilocularis FTZ F1 alpha 0.0012 0.0074 0.0072
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0207 0.0651
Brugia malayi MH1 domain containing protein 0.001 0.0044 0.0042
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0008 0.0026 0.0026
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0019 0.016 0.0154
Trypanosoma cruzi cysteine peptidase, putative 0.0062 0.069 0.0685
Mycobacterium leprae PROBABLE BACTERIOFERRITIN BFRA 0.0008 0.0024 0.0059
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0123 0.0397
Schistosoma mansoni malate dehydrogenase 0.0255 0.3105 0.3105
Trypanosoma cruzi glycosomal malate dehydrogenase, putative 0.0249 0.3023 0.3019
Trichomonas vaginalis antibiotic synthetase, putative 0.0007 0.0006 0.0018
Loa Loa (eye worm) hypothetical protein 0.0043 0.0464 0.0464
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0123 0.0349
Loa Loa (eye worm) hypothetical protein 0.0066 0.0739 0.0739
Brugia malayi Cathepsin L-like cysteine proteinase 0.0011 0.0057 0.0055
Loa Loa (eye worm) hypothetical protein 0.0007 0.0006 0.0006
Schistosoma mansoni aldehyde dehydrogenase 0.0067 0.0753 0.0753
Entamoeba histolytica cysteine protease, putative 0.0008 0.0026 0.003
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0207 0.0205
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0015 0.0115 0.0109
Loa Loa (eye worm) isocitrate dehydrogenase 0.0019 0.016 0.016
Onchocerca volvulus 0.0016 0.0123 0.0424
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0154 0.0149
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0007 0.0006 0.0003
Echinococcus granulosus malate dehydrogenase 0.0249 0.3023 0.3022
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0007 0.0006 0.0006
Mycobacterium tuberculosis Probable malate dehydrogenase Mdh 0.0255 0.3105 0.917
Loa Loa (eye worm) RecQ helicase 0.0029 0.0283 0.0283
Schistosoma mansoni microtubule-associated protein tau 0.0667 0.8235 0.8235
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0154 0.0149
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0123 0.0397
Brugia malayi ecdysteroid receptor 0.0012 0.0074 0.0072
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.069 0.0685
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0152 0.1817 0.1816
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0023 0.0207 0.0651
Echinococcus multilocularis isocitrate dehydrogenase 0.0019 0.016 0.0158
Echinococcus granulosus carbonic anhydrase 0.0438 0.5379 0.5379
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0123 0.0397
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0016 0.0124 0.0401
Trypanosoma cruzi cytosolic malate dehydrogenase, putative 0.0255 0.3105 0.3101
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.069 0.0685
Mycobacterium tuberculosis Conserved protein 0.0043 0.0464 0.1356
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.001 0.0042 0.004
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0067 0.0759 0.0757
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0123 0.0349
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.002 0.0166 0.0241
Brugia malayi F/Y-rich N-terminus family protein 0.0012 0.0067 0.0065
Loa Loa (eye worm) hypothetical protein 0.0012 0.0071 0.0071
Trichomonas vaginalis malate dehydrogenase, putative 0.0255 0.3105 1
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0012 0.0074 0.0072
Brugia malayi nuclear receptor NHR-88 0.0012 0.0074 0.0072
Echinococcus granulosus cytosolic malate dehydrogenase 0.0255 0.3105 0.3104
Trypanosoma cruzi cysteine peptidase, putative 0.0016 0.0123 0.0118
Loa Loa (eye worm) hypothetical protein 0.0017 0.0135 0.0135
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0123 0.0349
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0006 0 0.00000000019817
Loa Loa (eye worm) hypothetical protein 0.0023 0.0207 0.0207
Echinococcus multilocularis short transient receptor potential channel 6 0.0078 0.0888 0.0887
Loa Loa (eye worm) hypothetical protein 0.0043 0.0464 0.0464
Mycobacterium ulcerans esterase/lipase LipP 0.0043 0.0464 0.1479
Loa Loa (eye worm) bromodomain containing protein 0.0019 0.0164 0.0164
Schistosoma mansoni nuclear hormone receptor 0.0012 0.0074 0.0074
Mycobacterium ulcerans bacterioferritin BfrB 0.0008 0.0024 0.0059
Trichomonas vaginalis set domain proteins, putative 0.0229 0.2783 0.8962
Schistosoma mansoni hypothetical protein 0.0152 0.1817 0.1817
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0012 0.0074 0.0072
Onchocerca volvulus Cathepsin L homolog 0.0016 0.0123 0.0424
Schistosoma mansoni transient receptor potential channel 0.0078 0.0888 0.0888
Schistosoma mansoni ferritin 0.0008 0.0024 0.0024
Trichomonas vaginalis DNA helicase recq, putative 0.0029 0.0283 0.0912
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0123 0.0397
Loa Loa (eye worm) hypothetical protein 0.0023 0.0207 0.0207
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0016 0.0124 0.0428
Schistosoma mansoni hypothetical protein 0.0354 0.4335 0.4335
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0016 0.0124 0.0119
Schistosoma mansoni RAR-like nuclear receptor 0.0012 0.0074 0.0074
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0008 0.0026 0.0082
Schistosoma mansoni hypothetical protein 0.0438 0.5379 0.5379
Brugia malayi Cathepsin L-like precursor 0.0016 0.0123 0.0121
Mycobacterium leprae Probable lipase LipE 0.0043 0.0464 0.1479
Entamoeba histolytica cysteine proteinase, putative 0.0016 0.0123 0.0177
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0067 0.0753 0.0751
Brugia malayi Probable malate dehydrogenase, mitochondrial precursor 0.0249 0.3023 0.3022
Echinococcus granulosus neuropeptide s receptor 0.0448 0.5514 0.5513
Schistosoma mansoni ferritin 0.0008 0.0024 0.0024
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.069 0.0685
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0019 0.016 0.0232
Echinococcus multilocularis neutral alpha glucosidase AB 0.0044 0.0466 0.0464
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0016 0.0123 0.0177
Echinococcus multilocularis mothers against decapentaplegic 5 0.001 0.0044 0.0042
Echinococcus multilocularis lactate dehydrogenase a 0.054 0.6655 0.6654
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0067 0.0753 0.0751
Mycobacterium ulcerans lipase LipD 0.0043 0.0464 0.1479
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0123 0.0397
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0058 0.064 0.064
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0207 0.0205
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0006 0.0002 0.0002
Echinococcus granulosus methyl CpG binding domain protein 2 0.0019 0.0155 0.0153
Leishmania major glycosomal malate dehydrogenase 0.0249 0.3023 0.3019
Mycobacterium tuberculosis Conserved protein 0.0043 0.0464 0.1356
Schistosoma mansoni retinoic acid receptor RXR 0.0012 0.0074 0.0074
Loa Loa (eye worm) malate dehydrogenase 0.0255 0.3105 0.3105
Loa Loa (eye worm) hypothetical protein 0.0045 0.0479 0.0479
Trichomonas vaginalis maltase-glucoamylase, putative 0.0044 0.0466 0.1501
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0026 0.025 0.025
Trypanosoma cruzi cytosolic malate dehydrogenase, putative 0.0255 0.3105 0.3101
Schistosoma mansoni ferritin 0.0008 0.0024 0.0024
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0008 0.0026 0.002
Echinococcus granulosus cytosolic malate dehydrogenase 0.0255 0.3105 0.3104
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0008 0.0021 0.0019
Schistosoma mansoni mixed-lineage leukemia protein mll 0.006 0.0669 0.0669
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0043 0.0464 0.0464
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.069 0.0685
Trichomonas vaginalis malate and lactate dehydrogenase, putative 0.0255 0.3105 1
Echinococcus granulosus expressed protein 0.0008 0.0024 0.0022
Onchocerca volvulus 0.0012 0.0074 0.0246
Loa Loa (eye worm) hypothetical protein 0.0438 0.5379 0.5379
Echinococcus multilocularis neuropeptide s receptor 0.0448 0.5514 0.5513
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0123 0.0397
Loa Loa (eye worm) hypothetical protein 0.0048 0.0525 0.0525
Loa Loa (eye worm) hypothetical protein 0.0006 0.0002 0.0002
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0019 0.016 0.0232
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0066 0.0739 0.0737
Echinococcus granulosus lactate dehydrogenase protein 0.054 0.6655 0.6654
Trypanosoma cruzi cysteine peptidase, putative 0.0062 0.069 0.0685
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0043 0.0464 0.1356
Entamoeba histolytica cysteine proteinase, putative 0.0011 0.0057 0.0077
Trypanosoma cruzi cysteine protease, putative 0.0008 0.0026 0.002
Schistosoma mansoni thyroid hormone receptor 0.0164 0.197 0.197
Loa Loa (eye worm) hypothetical protein 0.0078 0.089 0.089
Brugia malayi cathepsin L-like precursor 0.0011 0.0057 0.0055
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0123 0.0397
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0012 0.0074 0.0072
Schistosoma mansoni apoferritin-2 0.0008 0.0024 0.0024
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0006 0 0.00000000019817
Brugia malayi Malate dehydrogenase, cytoplasmic 0.0255 0.3105 0.3104
Entamoeba histolytica malate dehydrogenase, putative 0.0255 0.3105 0.4661
Schistosoma mansoni malate dehydrogenase 0.0255 0.3105 0.3105
Brugia malayi PHD-finger family protein 0.0029 0.0282 0.028
Schistosoma mansoni DNA helicase recq5 0.0012 0.0071 0.0071
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0012 0.0074 0.0072
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0058 0.064 0.2284
Loa Loa (eye worm) hypothetical protein 0.0011 0.0057 0.0057
Trichomonas vaginalis malate and lactate dehydrogenase, putative 0.0255 0.3105 1
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0017 0.0135 0.0418
Leishmania major hypothetical protein, conserved 0.0017 0.0131 0.0126
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0123 0.0397
Schistosoma mansoni hypothetical protein 0.0035 0.0357 0.0357
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0012 0.0074 0.0074
Schistosoma mansoni carbonic anhydrase-related 0.0438 0.5379 0.5379
Brugia malayi Cathepsin L-like precursor 0.0016 0.0123 0.0121
Toxoplasma gondii lactate dehydrogenase LDH1 0.054 0.6655 1
Trypanosoma cruzi hypothetical protein, conserved 0.0044 0.0466 0.0461
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0012 0.0071 0.0069
Echinococcus multilocularis cathepsin L 0.0008 0.0026 0.0024
Loa Loa (eye worm) hypothetical protein 0.0048 0.0522 0.0522
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0012 0.0074 0.0072
Entamoeba histolytica cysteine protease, putative 0.0008 0.0026 0.003
Leishmania major cysteine peptidase A (CPA) 0.0016 0.0123 0.0118
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0012 0.0074 0.0074
Trichomonas vaginalis maltase-glucoamylase, putative 0.0016 0.0124 0.0401
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0067 0.0753 0.2211
Brugia malayi MH2 domain containing protein 0.0144 0.1719 0.1718
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0438 0.5379 0.5379
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0006 0 0.00000000019817
Loa Loa (eye worm) hypothetical protein 0.0043 0.0464 0.0464
Echinococcus granulosus lysosomal alpha glucosidase 0.0197 0.2375 0.2373
Trichomonas vaginalis malate dehydrogenase, putative 0.0255 0.3105 1
Onchocerca volvulus 0.0043 0.0464 0.165
Loa Loa (eye worm) PHD-finger family protein 0.0023 0.0204 0.0204
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0016 0.0123 0.0397
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0044 0.0466 0.1501
Trichomonas vaginalis alpha-glucosidase, putative 0.0016 0.0124 0.0401
Echinococcus granulosus carbonic anhydrase II 0.0808 1 1
Brugia malayi Cathepsin L-like precursor 0.0016 0.0123 0.0121
Schistosoma mansoni carbonic anhydrase 0.0438 0.5379 0.5379
Loa Loa (eye worm) hypothetical protein 0.0012 0.0074 0.0074
Schistosoma mansoni transient receptor potential channel 4 0.0117 0.1383 0.1383
Schistosoma mansoni cathepsin F (C01 family) 0.0016 0.0123 0.0123
Echinococcus granulosus SAM and MBT domain containing protein 0.0058 0.064 0.0638
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0023 0.0207 0.0651
Echinococcus multilocularis carbonic anhydrase 0.0438 0.5379 0.5379
Plasmodium falciparum lactate dehydrogenase, putative 0.0231 0.2805 0.421
Wolbachia endosymbiont of Brugia malayi malate dehydrogenase 0.054 0.6655 1
Brugia malayi AMP-binding enzyme family protein 0.0007 0.0006 0.0003
Brugia malayi Cathepsin L-like precursor 0.0016 0.0123 0.0121
Schistosoma mansoni methyl-cpg binding protein mbd 0.0019 0.0155 0.0155
Treponema pallidum exodeoxyribonuclease (exoA) 0.0019 0.0154 1
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0808 1 1
Plasmodium vivax vivapain-2 0.0016 0.0123 0.0177
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0043 0.0464 0.1356
Plasmodium falciparum malate dehydrogenase 0.054 0.6655 1
Trichomonas vaginalis malate dehydrogenase, putative 0.0255 0.3105 1
Trypanosoma cruzi cysteine peptidase, putative 0.0062 0.069 0.0685
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0016 0.0123 0.0121
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0438 0.5379 0.5379
Trichomonas vaginalis malate dehydrogenase, putative 0.0255 0.3105 1
Leishmania major alpha glucosidase II subunit, putative 0.0044 0.0466 0.0461
Schistosoma mansoni bromodomain containing protein 0.0071 0.0808 0.0808
Echinococcus granulosus carbonic anhydrase 0.0438 0.5379 0.5379
Toxoplasma gondii isocitrate dehydrogenase 0.0019 0.016 0.0232
Trichomonas vaginalis malate and lactate dehydrogenase, putative 0.0255 0.3105 1
Loa Loa (eye worm) hypothetical protein 0.0438 0.5379 0.5379
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0007 0.0006 0.0003
Brugia malayi Papain family cysteine protease containing protein 0.0016 0.0123 0.0121
Trichomonas vaginalis malate and lactate dehydrogenase, putative 0.0255 0.3105 1
Onchocerca volvulus 0.0058 0.064 0.2284
Trypanosoma brucei cytosolic malate dehydrogenase 0.0255 0.3105 0.3101
Echinococcus granulosus microtubule associated protein 2 0.0667 0.8235 0.8235
Loa Loa (eye worm) hypothetical protein 0.0011 0.0057 0.0057
Schistosoma mansoni smad1 5 8 and 0.001 0.0044 0.0044
Trichomonas vaginalis alpha-glucosidase, putative 0.0044 0.0466 0.1501
Mycobacterium tuberculosis Probable lipase LipE 0.0043 0.0464 0.1356
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0006 0 0.00000000019817
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.0357 0.0355
Echinococcus granulosus ecdysone induced protein 78C 0.0012 0.0074 0.0072
Echinococcus granulosus L lactate dehydrogenase 0.0309 0.3771 0.377
Toxoplasma gondii histone lysine methyltransferase SET1 0.0056 0.0623 0.0928
Mycobacterium leprae PROBABLE MALATE DEHYDROGENASE MDH 0.0255 0.3105 1
Brugia malayi steroid hormone receptor 0.0012 0.0074 0.0072
Brugia malayi AMP-binding enzyme family protein 0.0007 0.0006 0.0003
Brugia malayi Glycosyl hydrolases family 31 protein 0.0197 0.2375 0.2373
Entamoeba histolytica cysteine protease, putative 0.0016 0.0123 0.0177
Schistosoma mansoni apoferritin-2 0.0008 0.0024 0.0024
Entamoeba histolytica cysteine protease, putative 0.0008 0.0026 0.003
Plasmodium vivax acyl-CoA synthetase, putative 0.0017 0.0135 0.0195
Entamoeba histolytica cysteine protease, putative 0.0008 0.0026 0.003
Schistosoma mansoni ap endonuclease 0.0019 0.0154 0.0154
Echinococcus multilocularis cathepsin L cysteine protease 0.0016 0.0123 0.0121
Loa Loa (eye worm) hypothetical protein 0.0006 0.0002 0.0002
Schistosoma mansoni myelin transcription factor 1 myt1 0.0066 0.0739 0.0739
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0006 0.0002 0.0002
Trichomonas vaginalis alpha-glucosidase, putative 0.0016 0.0124 0.0401
Loa Loa (eye worm) cysteine protease 0.0016 0.0123 0.0123
Toxoplasma gondii hypothetical protein 0.0438 0.5379 0.8082
Onchocerca volvulus 0.0016 0.0123 0.0424
Trichomonas vaginalis penicillin-binding protein, putative 0.0043 0.0464 0.1494
Trichomonas vaginalis malate dehydrogenase, putative 0.0255 0.3105 1
Entamoeba histolytica hypothetical protein 0.0035 0.0357 0.0528
Brugia malayi MH1 domain containing protein 0.001 0.0044 0.0042
Leishmania major malate dehydrogenase, putative 0.0231 0.2805 0.2801
Schistosoma mansoni transient receptor potential channel 0.0117 0.1383 0.1383
Schistosoma mansoni hypothetical protein 0.0017 0.0131 0.0131
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0123 0.0397
Mycobacterium tuberculosis Conserved protein 0.0043 0.0464 0.1356
Leishmania major mitochondrial malate dehydrogenase 0.0249 0.3023 0.3019
Echinococcus granulosus smad 0.001 0.0044 0.0042
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.0008 0.0024 0.0054
Onchocerca volvulus Cathepsin L homolog 0.0016 0.0123 0.0424
Echinococcus granulosus short transient receptor potential channel 6 0.0078 0.0888 0.0887
Brugia malayi AMP-binding enzyme family protein 0.0007 0.0006 0.0003
Onchocerca volvulus 0.0028 0.0268 0.0944
Brugia malayi photoreceptor-specific nuclear receptor 0.0012 0.0074 0.0072
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0012 0.0074 0.0072
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0008 0.0021 0.0021
Schistosoma mansoni TGF-beta signal transducer Smad2 0.001 0.0044 0.0044
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0268 0.0266
Schistosoma mansoni zinc finger protein 0.0017 0.0131 0.0131
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0012 0.0074 0.0072
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0006 0 0.00000000019817
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0012 0.0071 0.0069
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0123 0.0397
Schistosoma mansoni thyroid hormone receptor 0.0164 0.197 0.197
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.069 0.0685
Trichomonas vaginalis esterase, putative 0.0043 0.0464 0.1494
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0048 0.0522 0.0522
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0012 0.0071 0.0069
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0006 0 0.00000000019817
Mycobacterium ulcerans bacterioferritin BfrA 0.0008 0.0024 0.0059
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0154 0.0152
Brugia malayi Putative carbonic anhydrase 5 precursor 0.0808 1 1
Toxoplasma gondii exonuclease III APE 0.0019 0.0154 0.0224
Loa Loa (eye worm) Smad1 0.001 0.0044 0.0044
Trypanosoma cruzi malate dehydrogenase, putative 0.0249 0.3023 0.3019
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0154 0.0149
Onchocerca volvulus 0.0043 0.0464 0.165
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0012 0.0071 0.0069
Toxoplasma gondii lactate dehydrogenase LDH2 0.054 0.6655 1
Schistosoma mansoni carbonic anhydrase-related 0.0438 0.5379 0.5379
Trichomonas vaginalis malate dehydrogenase, putative 0.0255 0.3105 1
Echinococcus multilocularis L lactate dehydrogenase B chain 0.054 0.6655 0.6654
Leishmania major glycosyl hydrolase-like protein 0.0016 0.0124 0.0119
Mycobacterium leprae conserved hypothetical protein 0.0043 0.0464 0.1479
Brugia malayi Nuclear hormone receptor-like 1 0.0012 0.0074 0.0072
Brugia malayi MH2 domain containing protein 0.001 0.0044 0.0042
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0066 0.0739 0.0737
Brugia malayi nuclear hormone receptor 0.0012 0.0074 0.0072
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.069 0.0685
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0012 0.0074 0.0074
Echinococcus granulosus transient receptor potential ion channel A 0.0113 0.1335 0.1333
Onchocerca volvulus Protein ultraspiracle homolog 0.0012 0.0074 0.0246
Loa Loa (eye worm) hypothetical protein 0.0012 0.0074 0.0074
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0123 0.0397
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0016 0.0123 0.0121
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0044 0.0466 0.0693
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0012 0.0074 0.0074
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.0357 0.0357
Loa Loa (eye worm) hypothetical protein 0.0006 0.0002 0.0002
Brugia malayi CXXC zinc finger family protein 0.0028 0.0268 0.0266
Echinococcus granulosus mothers against decapentaplegic 5 0.001 0.0044 0.0042
Trichomonas vaginalis ferritin, putative 0.0008 0.0024 0.0076
Trichomonas vaginalis DNA helicase recq, putative 0.0015 0.0115 0.037
Mycobacterium tuberculosis Bacterioferritin BfrB 0.0008 0.0024 0.0054
Plasmodium vivax unspecified product 0.0008 0.0026 0.003
Toxoplasma gondii aldehyde dehydrogenase 0.0067 0.0753 0.1124
Trypanosoma cruzi cysteine proteinase, putative 0.0008 0.0026 0.002
Echinococcus granulosus histone lysine methyltransferase setb 0.0048 0.0522 0.052
Entamoeba histolytica cysteine protease, putative 0.0008 0.0026 0.003
Onchocerca volvulus 0.0016 0.0123 0.0424
Loa Loa (eye worm) hypothetical protein 0.0016 0.0123 0.0123
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0023 0.0207 0.0651
Echinococcus multilocularis ecdysone induced protein 78C 0.0012 0.0074 0.0072
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0012 0.0074 0.0072
Brugia malayi beta-lactamase family protein 0.0043 0.0464 0.0462
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0154 0.0497
Schistosoma mansoni steroid hormone receptor ad4bp 0.0012 0.0074 0.0074
Schistosoma mansoni DNA helicase recq1 0.0012 0.0071 0.0071
Schistosoma mansoni cpg binding protein 0.0028 0.0268 0.0268
Trichomonas vaginalis penicillin-binding protein, putative 0.0043 0.0464 0.1494
Schistosoma mansoni alpha glucosidase 0.0044 0.0466 0.0466
Schistosoma mansoni cpg binding protein 0.0031 0.0314 0.0314
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0006 0 0.00000000019817
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0012 0.0074 0.0072
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.0207 0.0303
Trichomonas vaginalis malate dehydrogenase, putative 0.0255 0.3105 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0012 0.0074 0.0074
Onchocerca volvulus 0.0016 0.0123 0.0424
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0012 0.0074 0.0072
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0007 0.0006 0.0003
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0029 0.0289 0.0426
Plasmodium falciparum acyl-CoA synthetase 0.0017 0.0135 0.0195
Brugia malayi beta-lactamase 0.0043 0.0464 0.0462
Onchocerca volvulus 0.0016 0.0123 0.0424
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0006 0.0002 0.0002
Echinococcus multilocularis cysteine protease 0.0016 0.0123 0.0121
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0019 0.016 0.0158
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0012 0.0071 0.0098
Plasmodium vivax vivapain-3 0.0008 0.0026 0.003
Echinococcus granulosus FTZ F1 alpha 0.0012 0.0074 0.0072
Entamoeba histolytica cysteine proteinase, putative 0.0008 0.0026 0.003
Loa Loa (eye worm) malate dehydrogenase 0.0249 0.3023 0.3023
Echinococcus multilocularis cathepsin L cysteine protease 0.0016 0.0123 0.0121
Loa Loa (eye worm) hypothetical protein 0.0006 0.0002 0.0002
Loa Loa (eye worm) beta-lactamase 0.0043 0.0464 0.0464
Brugia malayi Cathepsin L-like precursor 0.0011 0.0057 0.0055
Echinococcus granulosus carbonic anhydrase 0.0438 0.5379 0.5379
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0019 0.016 0.0154
Onchocerca volvulus 0.0043 0.0464 0.165
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0044 0.0475 0.0473
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0043 0.0464 0.0462
Echinococcus granulosus neutral alpha glucosidase AB 0.0044 0.0466 0.0464
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0007 0.0006 0.0006
Trichomonas vaginalis alpha-glucosidase, putative 0.0044 0.0466 0.1501
Schistosoma mansoni Smad4 0.001 0.0044 0.0044
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0123 0.0397
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0023 0.0207 0.0597
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0044 0.0475 0.0473
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.069 0.0685
Loa Loa (eye worm) MH1 domain-containing protein 0.001 0.0044 0.0044
Echinococcus multilocularis ferritin 0.0008 0.0024 0.0022
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.0154 0.0441
Schistosoma mansoni malate dehydrogenase 0.054 0.6655 0.6655
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0017 0.0135 0.0383
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0012 0.0074 0.0074
Schistosoma mansoni cathepsin F (C01 family) 0.0016 0.0123 0.0123
Leishmania major cathepsin L-like protease 0.0016 0.0123 0.0118
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0012 0.0074 0.0072
Echinococcus granulosus cathepsin L 0.0008 0.0026 0.0024
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0008 0.0026 0.002
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0012 0.0074 0.0072
Onchocerca volvulus 0.0029 0.0289 0.102
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0019 0.0163 0.0237
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0016 0.0123 0.0177
Schistosoma mansoni coup transcription factor 0.0012 0.0074 0.0074
Brugia malayi Bloom's syndrome protein homolog 0.0029 0.0283 0.0281
Echinococcus multilocularis cpg binding protein 0.0031 0.0314 0.0312
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0154 0.0152
Echinococcus granulosus transient receptor potential gamma protein 0.0117 0.1383 0.1381
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0012 0.0071 0.0071
Echinococcus granulosus malate dehydrogenase 0.0249 0.3023 0.3022
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0008 0.0021 0.0019
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0012 0.0074 0.0074
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0438 0.5379 0.5379
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0012 0.0074 0.0074
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0044 0.0475 0.0473
Loa Loa (eye worm) hypothetical protein 0.0043 0.0464 0.0464
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0231 0.2799 0.2798
Trypanosoma brucei ISWI complex protein 0.0017 0.0131 0.0126
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0808 1 1
Entamoeba histolytica malate dehydrogenase,cytoplasmic, putative 0.0255 0.3105 0.4661
Loa Loa (eye worm) hypothetical protein 0.0058 0.064 0.064
Echinococcus multilocularis bloom syndrome protein 0.0029 0.0283 0.0281
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.0357 0.0355
Loa Loa (eye worm) hypothetical protein 0.054 0.6655 0.6655
Schistosoma mansoni blooms syndrome DNA helicase 0.0023 0.0207 0.0207
Trichomonas vaginalis alpha-glucosidase, putative 0.0016 0.0124 0.0401
Schistosoma mansoni alpha-glucosidase 0.0169 0.2033 0.2033
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0207 0.0651
Schistosoma mansoni ferritin 0.0008 0.0024 0.0024
Echinococcus granulosus dnaJ subfamily B 0.0395 0.4849 0.4848
Entamoeba histolytica cysteine protease, putative 0.0008 0.0026 0.003
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0012 0.0074 0.0072
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0207 0.0202
Brugia malayi Pre-SET motif family protein 0.0029 0.0289 0.0287
Schistosoma mansoni ap endonuclease 0.0019 0.0154 0.0154
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.0207 0.0303
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0012 0.0074 0.0072
Leishmania major cathepsin L-like protease 0.0016 0.0123 0.0118
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0123 0.0397
Echinococcus granulosus short transient receptor potential channel 6 0.0078 0.0888 0.0887
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0039 0.0414 0.0412
Loa Loa (eye worm) hypothetical protein 0.0117 0.1383 0.1383
Mycobacterium ulcerans aldehyde dehydrogenase 0.0067 0.0753 0.2411
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.069 0.0685
Trypanosoma brucei glucosidase, putative 0.0044 0.0466 0.0461
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0019 0.016 0.0158
Trypanosoma brucei glycosyl hydrolase-like protein 0.0016 0.0124 0.0119
Mycobacterium ulcerans aldehyde dehydrogenase 0.0067 0.0753 0.2411
Loa Loa (eye worm) fibroinase 0.0016 0.0123 0.0123
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0008 0.0026 0.0026
Mycobacterium ulcerans hypothetical protein 0.0023 0.0207 0.0651
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0019 0.0154 0.0275
Onchocerca volvulus 0.0016 0.0123 0.0424
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0043 0.0464 0.1356
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0123 0.0397
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0008 0.0021 0.0019
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0048 0.0522 0.0522
Onchocerca volvulus 0.0229 0.2783 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0016 0.0123 0.0397
Entamoeba histolytica cysteine proteinase 2 0.0008 0.0026 0.003
Trypanosoma cruzi cysteine peptidase, putative 0.0008 0.0026 0.002
Echinococcus multilocularis lysosomal alpha glucosidase 0.0197 0.2375 0.2373
Trypanosoma cruzi malate dehydrogenase, putative 0.0231 0.2805 0.2801
Leishmania major cathepsin L-like protease 0.0016 0.0123 0.0118
Echinococcus multilocularis smad 0.001 0.0044 0.0042
Entamoeba histolytica cysteine protease, putative 0.0008 0.0026 0.003
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0012 0.0074 0.0072
Onchocerca volvulus 0.0011 0.0057 0.0184
Echinococcus granulosus TGF beta signal transducer SmadC 0.001 0.0044 0.0042
Brugia malayi lactate dehydrogenase. 0.054 0.6655 0.6654
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0012 0.0074 0.0074
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0152 0.1817 0.1816
Loa Loa (eye worm) mbt repeat family protein 0.0058 0.064 0.064
Trichomonas vaginalis DNA helicase recq1, putative 0.0029 0.0283 0.0912
Loa Loa (eye worm) ctsf protein 0.0016 0.0123 0.0123
Echinococcus granulosus lactate dehydrogenase a 0.054 0.6655 0.6654
Entamoeba histolytica cysteine proteinase 1, putative 0.0008 0.0026 0.003
Mycobacterium ulcerans aldehyde dehydrogenase 0.0067 0.0753 0.2411
Echinococcus multilocularis TGF beta signal transducer SmadC 0.001 0.0044 0.0042
Brugia malayi Isocitrate dehydrogenase 0.0019 0.016 0.0158
Echinococcus granulosus cathepsin l1 0.0011 0.0057 0.0055
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.0475 0.0475
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0015 0.0115 0.0109
Loa Loa (eye worm) carbonic anhydrase 3 0.0808 1 1
Plasmodium vivax SET domain protein, putative 0.0029 0.0289 0.0426
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0012 0.0074 0.0072
Trypanosoma brucei hypothetical protein, conserved 0.0043 0.0464 0.0459
Toxoplasma gondii cathepsin CPL 0.0016 0.0123 0.0177
Leishmania major carbonic anhydrase-like protein 0.0808 1 1
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0012 0.0074 0.0072
Schistosoma mansoni sex comb on midleg homolog 0.0058 0.064 0.064
Trichomonas vaginalis alpha-glucosidase, putative 0.0044 0.0466 0.1501
Schistosoma mansoni alpha-glucosidase 0.0169 0.2033 0.2033
Schistosoma mansoni ferritin light chain 0.0008 0.0024 0.0024
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0029 0.0289 0.0289
Loa Loa (eye worm) hypothetical protein 0.0146 0.1741 0.1741
Trypanosoma cruzi hypothetical protein, conserved 0.0044 0.0466 0.0461
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0123 0.0397
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0019 0.016 0.0154
Loa Loa (eye worm) MH2 domain-containing protein 0.001 0.0044 0.0044
Trichomonas vaginalis D-aminoacylase, putative 0.0043 0.0464 0.1494
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0012 0.0074 0.0072
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0056 0.0624 0.0618
Loa Loa (eye worm) histone methyltransferase 0.001 0.0042 0.0042
Brugia malayi mbt repeat family protein 0.0058 0.064 0.0638
Brugia malayi Bromodomain containing protein 0.0084 0.0968 0.0966
Trichomonas vaginalis malate dehydrogenase, putative 0.0255 0.3105 1
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0012 0.0074 0.0072
Trypanosoma cruzi ISWI complex protein 0.0017 0.0131 0.0126
Schistosoma mansoni malate dehydrogenase 0.0249 0.3023 0.3023
Brugia malayi Glycosyl hydrolases family 31 protein 0.0016 0.0124 0.0122
Echinococcus multilocularis microtubule associated protein 2 0.0667 0.8235 0.8235
Schistosoma mansoni L-lactate dehydrogenase 0.054 0.6655 0.6655
Loa Loa (eye worm) hypothetical protein 0.0016 0.0124 0.0124
Schistosoma mansoni L-lactate dehydrogenase 0.0231 0.2805 0.2805
Trypanosoma cruzi cysteine proteinase, putative 0.0008 0.0026 0.002
Brugia malayi Pre-SET motif family protein 0.0202 0.2436 0.2435
Brugia malayi MH2 domain containing protein 0.001 0.0044 0.0042
Echinococcus multilocularis polycomb protein SCMH1 0.0058 0.064 0.0638
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0019 0.0155 0.0153
Onchocerca volvulus 0.0023 0.0207 0.0726
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0008 0.0026 0.0082
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0044 0.0475 0.0475
Leishmania major hypothetical protein, conserved 0.0043 0.0464 0.0459
Echinococcus multilocularis L lactate dehydrogenase 0.0309 0.3771 0.377
Leishmania major cathepsin L-like protease 0.0016 0.0123 0.0118
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0268 0.0268
Trichomonas vaginalis D-aminoacylase, putative 0.0043 0.0464 0.1494
Schistosoma mansoni acetyl-CoA synthetase 0.0007 0.0006 0.0006
Entamoeba histolytica recQ family helicase, putative 0.0015 0.0115 0.0164
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.0475 0.0475
Leishmania major cathepsin L-like protease 0.0016 0.0123 0.0118
Brugia malayi mbt repeat family protein 0.0058 0.064 0.0638
Echinococcus granulosus fetal alzheimer antigen falz 0.0026 0.025 0.0248
Brugia malayi Steroid receptor seven-up type 2 0.0012 0.0074 0.0072
Trichomonas vaginalis malate dehydrogenase, putative 0.0231 0.2805 0.9034
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0154 0.0152
Onchocerca volvulus Cathepsin F homolog 0.0016 0.0123 0.0424
Brugia malayi Smad1 0.001 0.0044 0.0042
Schistosoma mansoni carbonic anhydrase-related 0.0438 0.5379 0.5379
Echinococcus multilocularis cytosolic malate dehydrogenase 0.0255 0.3105 0.3104
Chlamydia trachomatis malate dehydrogenase 0.0255 0.3105 1
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0012 0.0074 0.0072
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0008 0.0026 0.0026
Mycobacterium ulcerans malate dehydrogenase 0.0255 0.3105 1
Schistosoma mansoni hypothetical protein 0.0395 0.4849 0.4849
Entamoeba histolytica cysteine protease, putative 0.0008 0.0026 0.003
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0044 0.0475 0.0473
Echinococcus granulosus histone acetyltransferase MYST2 0.0066 0.0739 0.0737
Echinococcus multilocularis neuropeptide receptor A26 0.0448 0.5514 0.5513
Onchocerca volvulus Bile acid receptor homolog 0.0012 0.0074 0.0246
Echinococcus multilocularis dnaJ subfamily B 0.0395 0.4849 0.4848
Brugia malayi Transient-receptor-potential like protein 0.0044 0.0465 0.0463
Trichomonas vaginalis sucrase-isomaltase, putative 0.0044 0.0466 0.1501
Loa Loa (eye worm) hypothetical protein 0.0023 0.0207 0.0207
Brugia malayi Cathepsin L-like precursor 0.0016 0.0123 0.0121
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0023 0.0207 0.0651
Loa Loa (eye worm) hypothetical protein 0.0017 0.0135 0.0135
Echinococcus granulosus ferritin 0.0008 0.0024 0.0022
Plasmodium falciparum carbonic anhydrase 0.0438 0.5379 0.8082
Entamoeba histolytica cysteine proteinase, putative 0.0008 0.0026 0.003
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0044 0.0466 0.0466
Entamoeba histolytica cysteine protease, putative 0.0008 0.0026 0.003
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0019 0.016 0.0154
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0012 0.0074 0.0074
Entamoeba histolytica hypothetical protein 0.0035 0.0357 0.0528
Loa Loa (eye worm) hypothetical protein 0.0017 0.0135 0.0135
Loa Loa (eye worm) hypothetical protein 0.0012 0.0074 0.0074
Brugia malayi Papain family cysteine protease containing protein 0.0008 0.0026 0.0024
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0015 0.0115 0.0109
Schistosoma mansoni methyl-cpg binding protein mbd 0.0019 0.0155 0.0155
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0012 0.0074 0.0072
Loa Loa (eye worm) transcription factor SMAD2 0.0144 0.1719 0.1719
Plasmodium vivax lactate dehydrogenase 0.054 0.6655 1
Schistosoma mansoni hypothetical protein 0.0023 0.0204 0.0204
Echinococcus multilocularis cytosolic malate dehydrogenase 0.0255 0.3105 0.3104
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0039 0.0414 0.0412
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0012 0.0074 0.0072
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0012 0.0074 0.0072
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0025 0.0239 0.0352
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0808 1 1
Mycobacterium ulcerans hypothetical protein 0.0043 0.0464 0.1479
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0012 0.0074 0.0072
Echinococcus granulosus Smad4 0.001 0.0044 0.0042
Echinococcus multilocularis thyroid hormone receptor alpha 0.0164 0.197 0.1968
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0438 0.5379 0.5379
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0023 0.0207 0.0651
Trypanosoma cruzi glycosomal malate dehydrogenase, putative 0.0249 0.3023 0.3019
Echinococcus multilocularis beta LACTamase domain containing family member 0.0043 0.0464 0.0462
Loa Loa (eye worm) hypothetical protein 0.0012 0.0074 0.0074
Echinococcus granulosus cpg binding protein 0.0031 0.0314 0.0312
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0012 0.0074 0.0072
Trypanosoma cruzi major cysteine proteinase, putative 0.0048 0.0526 0.052
Trypanosoma brucei carbonic anhydrase-like protein 0.0808 1 1
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0202 0.2436 0.2436
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0043 0.0464 0.0464
Entamoeba histolytica hypothetical protein 0.0035 0.0357 0.0528
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0012 0.0074 0.0072
Trichomonas vaginalis malate dehydrogenase, putative 0.0113 0.1326 0.4272
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0808 1 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0123 0.0397
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0007 0.0006 0.0003
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0019 0.016 0.0158
Loa Loa (eye worm) hypothetical protein 0.0011 0.0057 0.0057
Echinococcus multilocularis expressed protein 0.0008 0.0024 0.0022
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0012 0.0071 0.0069
Loa Loa (eye worm) hypothetical protein 0.0074 0.084 0.084
Brugia malayi hypothetical protein 0.0035 0.0357 0.0355
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0066 0.0739 0.0737
Schistosoma mansoni aldehyde dehydrogenase 0.0067 0.0753 0.0753
Plasmodium vivax vivapain-1 0.0008 0.0026 0.003
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0048 0.0522 0.052
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0044 0.0466 0.1501
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0012 0.0074 0.0246
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0029 0.0289 0.0287
Brugia malayi Glycosyl hydrolases family 31 protein 0.0044 0.0466 0.0464
Mycobacterium tuberculosis Probable lipase LipD 0.0043 0.0464 0.1356
Leishmania major malate dehydrogenase 0.0249 0.3023 0.3019
Trichomonas vaginalis alpha-glucosidase, putative 0.0016 0.0124 0.0401
Entamoeba histolytica cysteine protease, putative 0.0008 0.0026 0.003
Entamoeba histolytica cysteine protease, putative 0.0008 0.0026 0.003
Onchocerca volvulus 0.0016 0.0123 0.0424
Trichomonas vaginalis alpha-glucosidase, putative 0.0016 0.0124 0.0401
Echinococcus multilocularis transient receptor potential gamma protein 0.0117 0.1383 0.1381
Trichomonas vaginalis D-aminoacylase, putative 0.0043 0.0464 0.1494
Echinococcus granulosus cathepsin l cysteine peptidase 0.0016 0.0123 0.0121
Echinococcus multilocularis lactate dehydrogenase a 0.054 0.6655 0.6654
Entamoeba histolytica cysteine protease, putative 0.0008 0.0026 0.003
Loa Loa (eye worm) hypothetical protein 0.0006 0.0002 0.0002
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0016 0.0123 0.0123
Echinococcus granulosus bloom syndrome protein 0.0029 0.0283 0.0281
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0044 0.0466 0.0693
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0012 0.0071 0.0069
Loa Loa (eye worm) oxidoreductase 0.0007 0.0006 0.0006
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0044 0.0475 0.0473
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0067 0.0759 0.0757
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0123 0.0397
Plasmodium vivax hypothetical protein, conserved 0.0043 0.0464 0.0689
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0123 0.0397
Echinococcus multilocularis lactate dehydrogenase a 0.054 0.6655 0.6654
Schistosoma mansoni transient receptor potential channel 0.0078 0.0888 0.0888
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0067 0.0753 0.0748
Trypanosoma cruzi mitochondrial malate dehydrogenase, putative 0.0249 0.3023 0.3019
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0207 0.0205
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.0475 0.0475
Echinococcus multilocularis SAM and MBT domain containing protein 0.0058 0.064 0.0638
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0019 0.0154 0.0224
Plasmodium vivax vivapain-2 0.0016 0.0123 0.0177
Mycobacterium tuberculosis Probable hydrolase 0.0043 0.0464 0.1356
Entamoeba histolytica acyl-coA synthetase, putative 0.0023 0.0207 0.0303
Echinococcus granulosus beta LACTamase domain containing family member 0.0043 0.0464 0.0462
Trypanosoma brucei glycosomal malate dehydrogenase 0.0249 0.3023 0.3019

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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