Detailed information for compound 1458800

Basic information

Technical information
  • TDR Targets ID: 1458800
  • Name: 2-[3-(3,4-dichlorophenyl)-6,7-dihydro-5H-pyrr olo[2,1-b]imidazol-1-ium-1-yl]-1-phenothiazin -10-ylethanone
  • MW: 493.428 | Formula: C26H20Cl2N3OS+
  • H donors: 0 H acceptors: 1 LogP: 6.31 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(N1c2ccccc2Sc2c1cccc2)C[n+]1cc(n2c1CCC2)c1ccc(c(c1)Cl)Cl
  • InChi: 1S/C26H20Cl2N3OS/c27-18-12-11-17(14-19(18)28)22-15-29(25-10-5-13-30(22)25)16-26(32)31-20-6-1-3-8-23(20)33-24-9-4-2-7-21(24)31/h1-4,6-9,11-12,14-15H,5,10,13,16H2/q+1
  • InChiKey: BONOZTUZIIWFQU-UHFFFAOYSA-N  

Network

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Synonyms

  • 2-[3-(3,4-dichlorophenyl)-6,7-dihydro-5H-pyrrolo[2,1-b]imidazol-1-ium-1-yl]-1-phenothiazin-10-yl-ethanone
  • 2-[3-(3,4-dichlorophenyl)-6,7-dihydro-5H-pyrrolo[2,1-b]imidazol-1-ium-1-yl]-1-(10-phenothiazinyl)ethanone
  • STOCK4S-43152

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0043 0.0464 0.0464
Echinococcus granulosus TRP transient receptor potential channel 0.0044 0.0465 0.0463
Plasmodium falciparum carbonic anhydrase 0.0438 0.5379 0.8082
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.0207 0.0303
Loa Loa (eye worm) hypothetical protein 0.0011 0.0057 0.0057
Loa Loa (eye worm) carbonic anhydrase 3 0.0808 1 1
Brugia malayi Malate dehydrogenase, cytoplasmic 0.0255 0.3105 0.3104
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0012 0.0071 0.0069
Echinococcus granulosus methyl CpG binding domain protein 2 0.0019 0.0155 0.0153
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0123 0.0349
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0019 0.016 0.0158
Loa Loa (eye worm) MH2 domain-containing protein 0.001 0.0044 0.0044
Schistosoma mansoni TGF-beta signal transducer Smad2 0.001 0.0044 0.0044
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0006 0 0.00000000019817
Schistosoma mansoni sex comb on midleg homolog 0.0058 0.064 0.064
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0067 0.0759 0.0757
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0268 0.0266
Echinococcus multilocularis microtubule associated protein 2 0.0667 0.8235 0.8235
Trypanosoma cruzi major cysteine proteinase, putative 0.0048 0.0526 0.052
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0019 0.0154 0.0197
Echinococcus multilocularis beta LACTamase domain containing family member 0.0043 0.0464 0.0462
Trypanosoma brucei glycosyl hydrolase-like protein 0.0016 0.0124 0.0119
Schistosoma mansoni smad1 5 8 and 0.001 0.0044 0.0044
Leishmania major alpha glucosidase II subunit, putative 0.0044 0.0466 0.0461
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0123 0.0349
Trypanosoma cruzi mitochondrial malate dehydrogenase, putative 0.0249 0.3023 0.3019
Echinococcus multilocularis L lactate dehydrogenase B chain 0.054 0.6655 0.6654
Toxoplasma gondii hypothetical protein 0.0438 0.5379 0.8082
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0044 0.0465 0.0463
Echinococcus granulosus L lactate dehydrogenase B chain 0.054 0.6655 0.6654
Plasmodium vivax vivapain-2 0.0016 0.0123 0.0177
Trypanosoma cruzi ISWI complex protein 0.0017 0.0131 0.0126
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0007 0.0006 0.0003
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0008 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0012 0.0074 0.0074
Trichomonas vaginalis malate dehydrogenase, putative 0.0255 0.3105 1
Leishmania major malate dehydrogenase, putative 0.0231 0.2805 0.2801
Brugia malayi Bloom's syndrome protein homolog 0.0029 0.0283 0.0281
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0023 0.0207 0.0651
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.0357 0.0355
Brugia malayi steroid hormone receptor 0.0012 0.0074 0.0072
Mycobacterium tuberculosis Conserved protein 0.0043 0.0464 0.1356
Schistosoma mansoni apoferritin-2 0.0008 0.0024 0.0024
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0123 0.0397
Brugia malayi MH1 domain containing protein 0.001 0.0044 0.0042
Entamoeba histolytica recQ family helicase, putative 0.0015 0.0115 0.0164
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0123 0.0397
Trypanosoma cruzi cysteine protease, putative 0.0008 0.0026 0.002
Trichomonas vaginalis maltase-glucoamylase, putative 0.0016 0.0124 0.0401
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0008 0.0021 0.0019
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0015 0.0115 0.0109
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0016 0.0124 0.0179
Brugia malayi mbt repeat family protein 0.0058 0.064 0.0638
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0016 0.0123 0.0397
Plasmodium vivax hypothetical protein, conserved 0.0043 0.0464 0.0689
Leishmania major cathepsin L-like protease 0.0062 0.069 0.0685
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0012 0.0074 0.0072
Schistosoma mansoni DNA helicase recq1 0.0012 0.0071 0.0071
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0207 0.0651
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0023 0.0207 0.0651
Trichomonas vaginalis D-aminoacylase, putative 0.0043 0.0464 0.1494
Trichomonas vaginalis esterase, putative 0.0043 0.0464 0.1494
Schistosoma mansoni zinc finger protein 0.0023 0.0209 0.0209
Plasmodium vivax vivapain-3 0.0008 0.0026 0.003
Schistosoma mansoni acetyl-CoA synthetase 0.0007 0.0006 0.0006
Onchocerca volvulus 0.0028 0.0268 0.0944
Echinococcus multilocularis smad 0.001 0.0044 0.0042
Trichomonas vaginalis DNA helicase recq1, putative 0.0029 0.0283 0.0912
Schistosoma mansoni L-lactate dehydrogenase 0.0231 0.2805 0.2805
Giardia lamblia Malate dehydrogenase 0.0255 0.3105 1
Loa Loa (eye worm) malate dehydrogenase 0.0249 0.3023 0.3023
Trichomonas vaginalis malate and lactate dehydrogenase, putative 0.0255 0.3105 1
Echinococcus granulosus lactate dehydrogenase a 0.054 0.6655 0.6654
Brugia malayi isocitrate dehydrogenase 0.0019 0.016 0.0158
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.0357 0.0357
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0012 0.0071 0.0098
Schistosoma mansoni carbonic anhydrase-related 0.0438 0.5379 0.5379
Loa Loa (eye worm) hypothetical protein 0.0012 0.0074 0.0074
Brugia malayi mbt repeat family protein 0.0058 0.064 0.0638
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0123 0.0397
Loa Loa (eye worm) fibroinase 0.0016 0.0123 0.0123
Trypanosoma cruzi cysteine proteinase, putative 0.0008 0.0026 0.002
Entamoeba histolytica acyl-coA synthetase, putative 0.0023 0.0207 0.0303
Loa Loa (eye worm) hypothetical protein 0.0023 0.0207 0.0207
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0012 0.0074 0.0074
Schistosoma mansoni hypothetical protein 0.0395 0.4849 0.4849
Schistosoma mansoni ap endonuclease 0.0019 0.0154 0.0154
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0012 0.0074 0.0072
Onchocerca volvulus Protein ultraspiracle homolog 0.0012 0.0074 0.0246
Brugia malayi Papain family cysteine protease containing protein 0.0016 0.0123 0.0121
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0007 0.0006 0.0006
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0154 0.0224
Schistosoma mansoni DNA helicase recq5 0.0012 0.0071 0.0071
Leishmania major carbonic anhydrase-like protein 0.0808 1 1
Echinococcus multilocularis cathepsin L cysteine protease 0.0016 0.0123 0.0121
Echinococcus granulosus cytosolic malate dehydrogenase 0.0255 0.3105 0.3104
Schistosoma mansoni myelin transcription factor 1 myt1 0.0066 0.0739 0.0739
Echinococcus multilocularis mothers against decapentaplegic 5 0.001 0.0044 0.0042
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0019 0.016 0.0154
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0207 0.0202
Echinococcus granulosus carbonic anhydrase 0.0438 0.5379 0.5379
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0015 0.0115 0.0109
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0012 0.0071 0.0069
Loa Loa (eye worm) hypothetical protein 0.0043 0.0464 0.0464
Echinococcus granulosus malate dehydrogenase 0.0249 0.3023 0.3022
Loa Loa (eye worm) hypothetical protein 0.0044 0.0465 0.0465
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0012 0.0074 0.0072
Onchocerca volvulus Cathepsin L homolog 0.0016 0.0123 0.0424
Entamoeba histolytica malate dehydrogenase, putative 0.054 0.6655 1
Schistosoma mansoni blooms syndrome DNA helicase 0.0023 0.0207 0.0207
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0152 0.1817 0.1816
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0023 0.0207 0.0651
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0048 0.0522 0.0522
Echinococcus multilocularis expressed protein 0.0008 0.0024 0.0022
Mycobacterium tuberculosis Conserved protein 0.0043 0.0464 0.1356
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0123 0.0397
Trichomonas vaginalis set domain proteins, putative 0.0229 0.2783 0.8962
Brugia malayi Smad1 0.001 0.0044 0.0042
Schistosoma mansoni coup transcription factor 0.0012 0.0074 0.0074
Loa Loa (eye worm) hypothetical protein 0.0058 0.064 0.064
Loa Loa (eye worm) hypothetical protein 0.0043 0.0464 0.0464
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0008 0.0026 0.0026
Trichomonas vaginalis alpha-glucosidase, putative 0.0044 0.0466 0.1501
Onchocerca volvulus 0.0016 0.0123 0.0424
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.069 0.0685
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0808 1 1
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0058 0.064 0.064
Loa Loa (eye worm) hypothetical protein 0.0006 0.0002 0.0002
Trypanosoma brucei glucosidase, putative 0.0044 0.0466 0.0461
Schistosoma mansoni ferritin 0.0008 0.0024 0.0024
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0123 0.0397
Brugia malayi cathepsin L-like precursor 0.0011 0.0057 0.0055
Echinococcus granulosus lactate dehydrogenase a 0.054 0.6655 0.6654
Echinococcus granulosus ecdysone induced protein 78C 0.0012 0.0074 0.0072
Brugia malayi beta-lactamase family protein 0.0043 0.0464 0.0462
Leishmania major cathepsin L-like protease 0.0016 0.0123 0.0118
Loa Loa (eye worm) hypothetical protein 0.0078 0.089 0.089
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.0475 0.0475
Loa Loa (eye worm) hypothetical protein 0.0023 0.0207 0.0207
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0123 0.0397
Brugia malayi Probable malate dehydrogenase, mitochondrial precursor 0.0249 0.3023 0.3022
Leishmania major cysteine peptidase A (CPA) 0.0016 0.0123 0.0118
Schistosoma mansoni aldehyde dehydrogenase 0.0067 0.0753 0.0753
Echinococcus granulosus neuropeptide s receptor 0.0448 0.5514 0.5513
Echinococcus multilocularis cytosolic malate dehydrogenase 0.0255 0.3105 0.3104
Mycobacterium ulcerans lipase LipD 0.0043 0.0464 0.1479
Loa Loa (eye worm) hypothetical protein 0.0117 0.1383 0.1383
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0438 0.5379 0.5379
Loa Loa (eye worm) hypothetical protein 0.0006 0.0002 0.0002
Echinococcus multilocularis neutral alpha glucosidase AB 0.0044 0.0466 0.0464
Echinococcus granulosus SAM and MBT domain containing protein 0.0058 0.064 0.0638
Entamoeba histolytica cysteine proteinase, putative 0.0008 0.0026 0.003
Plasmodium vivax acyl-CoA synthetase, putative 0.0017 0.0135 0.0195
Trichomonas vaginalis malate dehydrogenase, putative 0.0255 0.3105 1
Brugia malayi Cathepsin L-like cysteine proteinase 0.0011 0.0057 0.0055
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0808 1 1
Echinococcus granulosus lactate dehydrogenase protein 0.054 0.6655 0.6654
Leishmania major cytosolic malate dehydrogenase 0.0255 0.3105 0.3101
Loa Loa (eye worm) malate dehydrogenase 0.0255 0.3105 0.3105
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0012 0.0074 0.0074
Loa Loa (eye worm) hypothetical protein 0.0074 0.084 0.084
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0231 0.2799 0.2798
Entamoeba histolytica cysteine protease, putative 0.0008 0.0026 0.003
Brugia malayi Steroid receptor seven-up type 2 0.0012 0.0074 0.0072
Onchocerca volvulus 0.0043 0.0464 0.165
Onchocerca volvulus 0.0058 0.064 0.2284
Echinococcus multilocularis neuropeptide s receptor 0.0448 0.5514 0.5513
Trichomonas vaginalis sucrase-isomaltase, putative 0.0044 0.0466 0.1501
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0016 0.0123 0.0121
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0043 0.0464 0.1356
Loa Loa (eye worm) MBCTL1 0.0066 0.0739 0.0739
Trypanosoma brucei mitochondrial malate dehydrogenase 0.0249 0.3023 0.3019
Echinococcus granulosus neuropeptide receptor A26 0.0448 0.5514 0.5513
Echinococcus granulosus lysosomal alpha glucosidase 0.0197 0.2375 0.2373
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0023 0.0207 0.0651
Echinococcus granulosus cpg binding protein 0.0031 0.0314 0.0312
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0268 0.0268
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0006 0.0002 0.0002
Echinococcus granulosus cytosolic malate dehydrogenase 0.0255 0.3105 0.3104
Echinococcus granulosus microtubule associated protein 2 0.0667 0.8235 0.8235
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0029 0.0289 0.0287
Loa Loa (eye worm) hypothetical protein 0.0043 0.0464 0.0464
Trichomonas vaginalis malate and lactate dehydrogenase, putative 0.0255 0.3105 1
Loa Loa (eye worm) hypothetical protein 0.054 0.6655 0.6655
Mycobacterium leprae PROBABLE MALATE DEHYDROGENASE MDH 0.0255 0.3105 1
Trypanosoma cruzi hypothetical protein, conserved 0.0043 0.0464 0.0459
Leishmania major glycosomal malate dehydrogenase 0.0249 0.3023 0.3019
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0207 0.0202
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.069 0.0685
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0039 0.0414 0.0412
Brugia malayi Papain family cysteine protease containing protein 0.0008 0.0026 0.0024
Echinococcus multilocularis carbonic anhydrase 0.0438 0.5379 0.5379
Trichomonas vaginalis malate and lactate dehydrogenase, putative 0.0255 0.3105 1
Mycobacterium ulcerans bacterioferritin BfrB 0.0008 0.0024 0.0059
Schistosoma mansoni Smad4 0.001 0.0044 0.0044
Schistosoma mansoni malate dehydrogenase 0.0255 0.3105 0.3105
Loa Loa (eye worm) transcription factor SMAD2 0.0144 0.1719 0.1719
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0067 0.0753 0.2211
Treponema pallidum exodeoxyribonuclease (exoA) 0.0019 0.0154 1
Echinococcus multilocularis malate dehydrogenase 0.0249 0.3023 0.3022
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0006 0 0.00000000019817
Brugia malayi Glycosyl hydrolases family 31 protein 0.0044 0.0466 0.0464
Trypanosoma cruzi hypothetical protein, conserved 0.0043 0.0464 0.0459
Echinococcus multilocularis histone acetyltransferase MYST2 0.0066 0.0739 0.0737
Echinococcus granulosus cysteine protease 0.0008 0.0026 0.0024
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0015 0.0115 0.0109
Echinococcus multilocularis transient receptor potential ion channel A 0.0113 0.1335 0.1333
Mycobacterium tuberculosis Probable lipase LipE 0.0043 0.0464 0.1356
Mycobacterium ulcerans aldehyde dehydrogenase 0.0067 0.0753 0.2411
Loa Loa (eye worm) hypothetical protein 0.0045 0.0479 0.0479
Echinococcus granulosus cathepsin l1 0.0011 0.0057 0.0055
Echinococcus granulosus histone lysine methyltransferase setb 0.0048 0.0522 0.052
Leishmania major malate dehydrogenase 0.0249 0.3023 0.3019
Loa Loa (eye worm) hypothetical protein 0.004 0.0417 0.0417
Trypanosoma cruzi cysteine proteinase, putative 0.0008 0.0026 0.002
Plasmodium falciparum lactate dehydrogenase, putative 0.0231 0.2805 0.421
Brugia malayi AMP-binding enzyme family protein 0.0007 0.0006 0.0003
Entamoeba histolytica cysteine protease, putative 0.0008 0.0026 0.003
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0043 0.0464 0.1479
Loa Loa (eye worm) hypothetical protein 0.0012 0.0074 0.0074
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0123 0.0397
Brugia malayi nuclear receptor NHR-88 0.0012 0.0074 0.0072
Trypanosoma cruzi malate dehydrogenase, putative 0.0249 0.3023 0.3019
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0012 0.0074 0.0072
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0044 0.0466 0.0693
Trypanosoma cruzi cytosolic malate dehydrogenase, putative 0.0255 0.3105 0.3101
Schistosoma mansoni bromodomain containing protein 0.0071 0.0808 0.0808
Trichomonas vaginalis antibiotic synthetase, putative 0.0007 0.0006 0.0018
Echinococcus multilocularis ferritin 0.0008 0.0024 0.0022
Echinococcus multilocularis zinc finger protein 0.0023 0.0209 0.0207
Brugia malayi nuclear hormone receptor 0.0012 0.0074 0.0072
Loa Loa (eye worm) hypothetical protein 0.0017 0.0135 0.0135
Loa Loa (eye worm) hypothetical protein 0.0048 0.0522 0.0522
Plasmodium vivax unspecified product 0.0008 0.0026 0.003
Loa Loa (eye worm) hypothetical protein 0.0011 0.0057 0.0057
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0019 0.016 0.0154
Echinococcus multilocularis cysteine protease 0.0016 0.0123 0.0121
Brugia malayi Cathepsin L-like precursor 0.0016 0.0123 0.0121
Mycobacterium tuberculosis Bacterioferritin BfrB 0.0008 0.0024 0.0054
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0019 0.0154 0.0224
Entamoeba histolytica malate dehydrogenase, putative 0.0255 0.3105 0.4661
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0808 1 1
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0044 0.0475 0.0473
Leishmania major glycosyl hydrolase-like protein 0.0016 0.0124 0.0119
Echinococcus granulosus cathepsin L 0.0008 0.0026 0.0024
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0008 0.0026 0.0082
Brugia malayi AMP-binding enzyme family protein 0.0007 0.0006 0.0003
Entamoeba histolytica cysteine proteinase, putative 0.0016 0.0123 0.0177
Onchocerca volvulus 0.0011 0.0057 0.0184
Schistosoma mansoni thyroid hormone receptor 0.0164 0.197 0.197
Schistosoma mansoni microtubule-associated protein tau 0.0667 0.8235 0.8235
Leishmania major cathepsin L-like protease 0.0016 0.0123 0.0118
Leishmania major hypothetical protein, conserved 0.0017 0.0131 0.0126
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0016 0.0123 0.0177
Schistosoma mansoni transient receptor potential channel 0.0078 0.0888 0.0888
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0012 0.0074 0.0072
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0152 0.1817 0.1816
Echinococcus granulosus carbonic anhydrase 0.0438 0.5379 0.5379
Echinococcus multilocularis carbonic anhydrase 0.0438 0.5379 0.5379
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0043 0.0464 0.1356
Schistosoma mansoni cathepsin F (C01 family) 0.0016 0.0123 0.0123
Onchocerca volvulus 0.0114 0.1341 0.4807
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0016 0.0123 0.0177
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0207 0.0651
Plasmodium vivax vivapain-2 0.0016 0.0123 0.0177
Schistosoma mansoni transient receptor potential channel 0.0078 0.0888 0.0888
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0207 0.0202
Schistosoma mansoni methyl-cpg binding protein mbd 0.0019 0.0155 0.0155
Echinococcus multilocularis Smad4 0.001 0.0044 0.0042
Entamoeba histolytica cysteine protease, putative 0.0008 0.0026 0.003
Trypanosoma brucei malate dehydrogenase-related 0.0231 0.2805 0.2801
Schistosoma mansoni nuclear hormone receptor 0.0012 0.0074 0.0074
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0808 1 1
Loa Loa (eye worm) mbt repeat family protein 0.0058 0.064 0.064
Echinococcus multilocularis carbonic anhydrase II 0.0808 1 1
Schistosoma mansoni zinc finger protein 0.0017 0.0131 0.0131
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0016 0.0123 0.0123
Brugia malayi MH2 domain containing protein 0.001 0.0044 0.0042
Toxoplasma gondii isocitrate dehydrogenase 0.0019 0.016 0.0232
Schistosoma mansoni malate dehydrogenase 0.054 0.6655 0.6655
Schistosoma mansoni ferritin 0.0008 0.0024 0.0024
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0123 0.0397
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.001 0.0042 0.004
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0019 0.0155 0.0153
Schistosoma mansoni carbonic anhydrase 0.0438 0.5379 0.5379
Echinococcus multilocularis malate dehydrogenase 0.0249 0.3023 0.3022
Entamoeba histolytica hypothetical protein 0.0035 0.0357 0.0528
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0025 0.0239 0.0352
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0019 0.016 0.0158
Brugia malayi AMP-binding enzyme family protein 0.0007 0.0006 0.0003
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0012 0.0074 0.0072
Loa Loa (eye worm) hypothetical protein 0.0012 0.0071 0.0071
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0023 0.0207 0.0651
Brugia malayi Cathepsin L-like precursor 0.0016 0.0123 0.0121
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0438 0.5379 0.5379
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0026 0.025 0.0248
Mycobacterium tuberculosis Conserved protein 0.0043 0.0464 0.1356
Trypanosoma cruzi cytosolic malate dehydrogenase, putative 0.0255 0.3105 0.3101
Schistosoma mansoni hypothetical protein 0.0017 0.0131 0.0131
Schistosoma mansoni hypothetical protein 0.0354 0.4335 0.4335
Toxoplasma gondii lactate dehydrogenase LDH1 0.054 0.6655 1
Leishmania major mitochondrial malate dehydrogenase 0.0249 0.3023 0.3019
Mycobacterium ulcerans esterase/lipase LipP 0.0043 0.0464 0.1479
Schistosoma mansoni smad1 5 8 and 0.001 0.0044 0.0044
Schistosoma mansoni steroid hormone receptor ad4bp 0.0012 0.0074 0.0074
Toxoplasma gondii aldehyde dehydrogenase 0.0067 0.0753 0.1124
Toxoplasma gondii malate dehydrogenase MDH 0.054 0.6655 1
Brugia malayi ecdysteroid receptor 0.0012 0.0074 0.0072
Echinococcus granulosus fetal alzheimer antigen falz 0.0026 0.025 0.0248
Echinococcus granulosus bloom syndrome protein 0.0029 0.0283 0.0281
Brugia malayi Cathepsin L-like precursor 0.0016 0.0123 0.0121
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0154 0.0224
Onchocerca volvulus 0.0043 0.0464 0.165
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0012 0.0074 0.0074
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0006 0 0.00000000019817
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.001 0.0042 0.004
Schistosoma mansoni ferritin light chain 0.0008 0.0024 0.0024
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0006 0 0.00000000019817
Brugia malayi Cathepsin L-like precursor 0.0016 0.0123 0.0121
Schistosoma mansoni cathepsin F (C01 family) 0.0016 0.0123 0.0123
Trypanosoma cruzi cysteine peptidase, putative 0.0062 0.069 0.0685
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0123 0.0397
Entamoeba histolytica cysteine proteinase, putative 0.0008 0.0026 0.003
Wolbachia endosymbiont of Brugia malayi malate dehydrogenase 0.054 0.6655 1
Trichomonas vaginalis malate dehydrogenase, putative 0.0255 0.3105 1
Echinococcus granulosus ferritin 0.0008 0.0024 0.0022
Leishmania major malate dehydrogenase, putative 0.054 0.6655 0.6653
Loa Loa (eye worm) hypothetical protein 0.0012 0.0074 0.0074
Trichomonas vaginalis penicillin-binding protein, putative 0.0043 0.0464 0.1494
Loa Loa (eye worm) hypothetical protein 0.0043 0.0464 0.0464
Loa Loa (eye worm) MH2 domain-containing protein 0.0144 0.1719 0.1719
Loa Loa (eye worm) steroid hormone receptor 0.0012 0.0074 0.0074
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0012 0.0074 0.0074
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0016 0.0124 0.0401
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0019 0.016 0.0456
Entamoeba histolytica cysteine proteinase, putative 0.0016 0.0123 0.0177
Trichomonas vaginalis alpha-glucosidase, putative 0.0044 0.0466 0.1501
Echinococcus multilocularis lactate dehydrogenase a 0.054 0.6655 0.6654
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0012 0.0074 0.0072
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0008 0.0026 0.0026
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0006 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0438 0.5379 0.5379
Loa Loa (eye worm) hypothetical protein 0.0006 0.0002 0.0002
Onchocerca volvulus 0.0023 0.0207 0.0726
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0012 0.0074 0.0074
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0007 0.0006 0.0003
Entamoeba histolytica cysteine proteinase, putative 0.0008 0.0026 0.003
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0123 0.0349
Loa Loa (eye worm) hypothetical protein 0.0012 0.0074 0.0074
Toxoplasma gondii isocitrate dehydrogenase 0.0019 0.016 0.0232
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0123 0.0397
Leishmania major cathepsin L-like protease 0.0062 0.069 0.0685
Brugia malayi hypothetical protein 0.0035 0.0357 0.0355
Plasmodium vivax vivapain-1 0.0008 0.0026 0.003
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0012 0.0074 0.0072
Toxoplasma gondii histone lysine methyltransferase SET1 0.0056 0.0623 0.0928
Schistosoma mansoni hypothetical protein 0.0152 0.1817 0.1817
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0123 0.0397
Loa Loa (eye worm) bromodomain containing protein 0.0019 0.0164 0.0164
Entamoeba histolytica malate dehydrogenase,cytoplasmic, putative 0.0255 0.3105 0.4661
Schistosoma mansoni mixed-lineage leukemia protein mll 0.006 0.0669 0.0669
Mycobacterium ulcerans hypothetical protein 0.0023 0.0207 0.0651
Echinococcus granulosus transient receptor potential ion channel A 0.0113 0.1335 0.1333
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0278 0.3386 1
Mycobacterium ulcerans hypothetical protein 0.0043 0.0464 0.1479
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0016 0.0124 0.0119
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0012 0.0074 0.0246
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0008 0.0021 0.0019
Schistosoma mansoni smad 0.001 0.0044 0.0044
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.069 0.0685
Echinococcus granulosus histone acetyltransferase MYST2 0.0066 0.0739 0.0737
Plasmodium falciparum cysteine proteinase falcipain 3 0.0016 0.0123 0.0177
Loa Loa (eye worm) hypothetical protein 0.0048 0.0525 0.0525
Trichomonas vaginalis alpha-glucosidase, putative 0.0016 0.0124 0.0401
Trichomonas vaginalis malate dehydrogenase, putative 0.0255 0.3105 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0006 0 0.00000000019817
Schistosoma mansoni ap endonuclease 0.0019 0.0154 0.0154
Trypanosoma brucei carbonic anhydrase-like protein 0.0808 1 1
Echinococcus granulosus smad 0.001 0.0044 0.0042
Onchocerca volvulus 0.0029 0.0289 0.102
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.0357 0.0355
Leishmania major cathepsin L-like protease 0.0016 0.0123 0.0118
Mycobacterium ulcerans aldehyde dehydrogenase 0.0067 0.0753 0.2411
Mycobacterium leprae Probable lipase LipE 0.0043 0.0464 0.1479
Plasmodium falciparum cysteine proteinase falcipain 1 0.0008 0.0026 0.003
Onchocerca volvulus Bile acid receptor homolog 0.0012 0.0074 0.0246
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0012 0.0074 0.0072
Trichomonas vaginalis alpha-glucosidase, putative 0.0016 0.0124 0.0401
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0006 0 0.00000000019817
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0023 0.0207 0.0597
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0066 0.0739 0.0737
Schistosoma mansoni hypothetical protein 0.0438 0.5379 0.5379
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0438 0.5379 0.5379
Entamoeba histolytica cysteine protease, putative 0.0008 0.0026 0.003
Echinococcus granulosus malate dehydrogenase 0.0249 0.3023 0.3022
Entamoeba histolytica cysteine protease, putative 0.0008 0.0026 0.003
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0012 0.0074 0.0072
Mycobacterium ulcerans malate dehydrogenase 0.0255 0.3105 1
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0008 0.0026 0.0026
Onchocerca volvulus 0.0016 0.0123 0.0424
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0043 0.0464 0.0462
Echinococcus multilocularis lysosomal alpha glucosidase 0.0197 0.2375 0.2373
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0012 0.0074 0.0074
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0154 0.0149
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0016 0.0124 0.0401
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0202 0.2436 0.2436
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0008 0.0026 0.0082
Entamoeba histolytica cysteine protease, putative 0.0008 0.0026 0.003
Loa Loa (eye worm) cysteine protease 0.0016 0.0123 0.0123
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0012 0.0074 0.0072
Echinococcus granulosus TGF beta signal transducer SmadC 0.001 0.0044 0.0042
Echinococcus multilocularis short transient receptor potential channel 6 0.0078 0.0888 0.0887
Trichomonas vaginalis ferritin, putative 0.0008 0.0024 0.0076
Echinococcus multilocularis carbonic anhydrase 0.0438 0.5379 0.5379
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0123 0.0397
Onchocerca volvulus 0.0016 0.0123 0.0424
Trichomonas vaginalis DNA helicase recq, putative 0.0015 0.0115 0.037
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0016 0.0123 0.0123
Loa Loa (eye worm) hypothetical protein 0.0012 0.0074 0.0074
Trichomonas vaginalis malate dehydrogenase, putative 0.0255 0.3105 1
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0154 0.0152
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0123 0.0397
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0019 0.016 0.016
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0012 0.0074 0.0072
Trypanosoma brucei cytosolic malate dehydrogenase 0.0255 0.3105 0.3101
Brugia malayi CXXC zinc finger family protein 0.0028 0.0268 0.0266
Schistosoma mansoni sex comb on midleg homolog 0.0058 0.064 0.064
Brugia malayi Bromodomain containing protein 0.0042 0.0446 0.0444
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0006 0 0.00000000019817
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0048 0.0522 0.0522
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0043 0.0464 0.1356
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0043 0.0464 0.0464
Loa Loa (eye worm) hypothetical protein 0.0438 0.5379 0.5379
Echinococcus granulosus beta LACTamase domain containing family member 0.0043 0.0464 0.0462
Echinococcus multilocularis lactate dehydrogenase a 0.054 0.6655 0.6654
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0438 0.5379 0.5379
Schistosoma mansoni ferritin light chain 0.0008 0.0024 0.0024
Loa Loa (eye worm) beta-lactamase 0.0043 0.0464 0.0464
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0012 0.0074 0.0074
Schistosoma mansoni L-lactate dehydrogenase 0.054 0.6655 0.6655
Brugia malayi Putative carbonic anhydrase 5 precursor 0.0808 1 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.069 0.0685
Entamoeba histolytica cysteine protease, putative 0.0016 0.0123 0.0177
Brugia malayi Nuclear hormone receptor-like 1 0.0012 0.0074 0.0072
Trichomonas vaginalis antibiotic synthetase, putative 0.0007 0.0006 0.0018
Brugia malayi MH2 domain containing protein 0.0144 0.1719 0.1718
Onchocerca volvulus 0.0016 0.0123 0.0424
Echinococcus multilocularis cathepsin L 0.0008 0.0026 0.0024
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0808 1 1
Loa Loa (eye worm) isocitrate dehydrogenase 0.0019 0.016 0.016
Entamoeba histolytica hypothetical protein 0.0035 0.0357 0.0528
Echinococcus multilocularis dnaJ subfamily B 0.0395 0.4849 0.4848
Trypanosoma cruzi cruzipain precursor, putative 0.0062 0.069 0.0685
Schistosoma mansoni malate dehydrogenase 0.0255 0.3105 0.3105
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.0008 0.0024 0.0054
Onchocerca volvulus 0.0016 0.0123 0.0424
Echinococcus granulosus zinc finger protein 0.0023 0.0209 0.0207
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0016 0.0124 0.0428
Echinococcus multilocularis cpg binding protein 0.0031 0.0314 0.0312
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0123 0.0397
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0019 0.016 0.0158
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0123 0.0397
Echinococcus granulosus carbonic anhydrase 0.0438 0.5379 0.5379
Trichomonas vaginalis malate dehydrogenase, putative 0.0113 0.1326 0.4272
Echinococcus multilocularis polycomb protein SCMH1 0.0058 0.064 0.0638
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0012 0.0071 0.0069
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.069 0.0685
Trichomonas vaginalis malate dehydrogenase, putative 0.0231 0.2805 0.9034
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0154 0.0152
Onchocerca volvulus 0.0229 0.2783 1
Trichomonas vaginalis alpha-glucosidase, putative 0.0016 0.0124 0.0401
Entamoeba histolytica cysteine proteinase 2 0.0008 0.0026 0.003
Loa Loa (eye worm) hypothetical protein 0.0012 0.0074 0.0074
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0019 0.016 0.0154
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0058 0.064 0.2284
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0012 0.0074 0.0072
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0012 0.0074 0.0072
Brugia malayi AMP-binding enzyme family protein 0.0007 0.0006 0.0003
Trichomonas vaginalis malate and lactate dehydrogenase, putative 0.0255 0.3105 1
Toxoplasma gondii cathepsin CPL 0.0016 0.0123 0.0177
Brugia malayi Pre-SET motif family protein 0.0202 0.2436 0.2435
Trichomonas vaginalis alpha-glucosidase, putative 0.0044 0.0466 0.1501
Trichomonas vaginalis alpha-glucosidase, putative 0.0044 0.0466 0.1501
Schistosoma mansoni apoferritin-2 0.0008 0.0024 0.0024
Onchocerca volvulus 0.0016 0.0123 0.0424
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0197 0.2375 0.2375
Brugia malayi Cathepsin L-like precursor 0.0011 0.0057 0.0055
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0044 0.0475 0.0473
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0012 0.0074 0.0072
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.069 0.0685
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0012 0.0074 0.0072
Brugia malayi Cathepsin L-like precursor 0.0016 0.0123 0.0121
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0029 0.0289 0.0289
Trichomonas vaginalis alpha-glucosidase, putative 0.0016 0.0124 0.0401
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0012 0.0074 0.0074
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.069 0.0685
Loa Loa (eye worm) hypothetical protein 0.0042 0.0447 0.0447
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0012 0.0074 0.0072
Loa Loa (eye worm) hypothetical protein 0.0043 0.0464 0.0464
Schistosoma mansoni malate dehydrogenase 0.0249 0.3023 0.3023
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0438 0.5379 0.5379
Mycobacterium leprae PROBABLE BACTERIOFERRITIN BFRA 0.0008 0.0024 0.0059
Brugia malayi Pre-SET motif family protein 0.0029 0.0289 0.0287
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0123 0.0397
Trichomonas vaginalis malate dehydrogenase, putative 0.0255 0.3105 1
Brugia malayi Cathepsin L-like precursor 0.0011 0.0057 0.0055
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0017 0.0135 0.0418
Loa Loa (eye worm) MH1 domain-containing protein 0.001 0.0044 0.0044
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.0475 0.0475
Leishmania major hypothetical protein, conserved 0.0043 0.0464 0.0459
Echinococcus multilocularis lysosomal alpha glucosidase 0.0197 0.2375 0.2373
Trypanosoma cruzi cysteine peptidase, putative 0.0016 0.0123 0.0118
Echinococcus granulosus cathepsin L cysteine proteinase 0.0016 0.0123 0.0121
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0123 0.0397
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0067 0.0753 0.0748
Mycobacterium ulcerans bacterioferritin BfrA 0.0008 0.0024 0.0059
Loa Loa (eye worm) hypothetical protein 0.0007 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0007 0.0006 0.0006
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0012 0.0074 0.0072
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0019 0.0154 0.0275
Loa Loa (eye worm) ctsf protein 0.0016 0.0123 0.0123
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.0475 0.0475
Loa Loa (eye worm) hypothetical protein 0.0016 0.0124 0.0124
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0123 0.0397
Echinococcus multilocularis thyroid hormone receptor alpha 0.0164 0.197 0.1968
Echinococcus granulosus L lactate dehydrogenase 0.0309 0.3771 0.377
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0123 0.0349
Schistosoma mansoni alpha glucosidase 0.0044 0.0466 0.0466
Echinococcus granulosus mothers against decapentaplegic 5 0.001 0.0044 0.0042
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0012 0.0071 0.0069
Schistosoma mansoni cpg binding protein 0.0031 0.0314 0.0314
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0044 0.0466 0.1501
Echinococcus multilocularis SAM and MBT domain containing protein 0.0058 0.064 0.0638
Trypanosoma cruzi hypothetical protein, conserved 0.0044 0.0466 0.0461
Trichomonas vaginalis malate dehydrogenase, putative 0.0255 0.3105 1
Echinococcus granulosus expressed protein 0.0008 0.0024 0.0022
Echinococcus multilocularis lactate dehydrogenase a 0.054 0.6655 0.6654
Echinococcus multilocularis cathepsin L cysteine protease 0.0016 0.0123 0.0121
Mycobacterium ulcerans aldehyde dehydrogenase 0.0067 0.0753 0.2411
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0207 0.0205
Toxoplasma gondii exonuclease III APE 0.0019 0.0154 0.0224
Loa Loa (eye worm) hypothetical protein 0.0066 0.0739 0.0739
Brugia malayi Cathepsin L-like precursor 0.0016 0.0123 0.0121
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.069 0.0685
Plasmodium falciparum acyl-CoA synthetase 0.0017 0.0135 0.0195
Chlamydia trachomatis malate dehydrogenase 0.0255 0.3105 1
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0067 0.0759 0.0757
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0123 0.0397
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0006 0 0.00000000019817
Loa Loa (eye worm) Smad1 0.001 0.0044 0.0044
Entamoeba histolytica cysteine proteinase 1, putative 0.0008 0.0026 0.003
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0023 0.0207 0.0651
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0019 0.0154 0.048
Entamoeba histolytica cysteine proteinase, putative 0.0011 0.0057 0.0077
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0067 0.0753 0.0751
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0066 0.0739 0.0737
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0012 0.0074 0.0072
Entamoeba histolytica hypothetical protein 0.0035 0.0357 0.0528
Loa Loa (eye worm) histone methyltransferase 0.001 0.0042 0.0042
Echinococcus multilocularis lactate dehydrogenase protein 0.054 0.6655 0.6654
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0016 0.0124 0.0119
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0123 0.0397
Loa Loa (eye worm) PHD-finger family protein 0.0023 0.0204 0.0204
Loa Loa (eye worm) hypothetical protein 0.0023 0.0207 0.0207
Schistosoma mansoni methyl-cpg binding protein mbd 0.0019 0.0155 0.0155
Brugia malayi MH2 domain containing protein 0.001 0.0044 0.0042
Echinococcus multilocularis cytosolic malate dehydrogenase 0.0255 0.3105 0.3104
Entamoeba histolytica cysteine protease, putative 0.0008 0.0026 0.003
Schistosoma mansoni cathepsin F (C01 family) 0.0011 0.0057 0.0057
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0006 0.0002 0.0002
Echinococcus multilocularis cysteine protease 0.0016 0.0123 0.0121
Trichomonas vaginalis penicillin-binding protein, putative 0.0043 0.0464 0.1494
Plasmodium falciparum malate dehydrogenase 0.054 0.6655 1
Loa Loa (eye worm) hypothetical protein 0.0438 0.5379 0.5379
Plasmodium vivax lactate/malate dehydrogenase, putative 0.0231 0.2805 0.421
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0019 0.016 0.0232
Trypanosoma cruzi malate dehydrogenase, putative 0.0231 0.2805 0.2801
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0012 0.0071 0.0069
Plasmodium falciparum L-lactate dehydrogenase 0.054 0.6655 1
Trichomonas vaginalis malate dehydrogenase, putative 0.0255 0.3105 1
Trypanosoma cruzi glycosomal malate dehydrogenase, putative 0.0249 0.3023 0.3019
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0048 0.0522 0.052
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0008 0.0026 0.002
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0154 0.0497
Schistosoma mansoni hypothetical protein 0.0023 0.0204 0.0204
Loa Loa (eye worm) hypothetical protein 0.0016 0.0123 0.0123
Trichomonas vaginalis malate dehydrogenase, putative 0.0255 0.3105 1
Onchocerca volvulus 0.0043 0.0464 0.165
Trypanosoma brucei hypothetical protein, conserved 0.0043 0.0464 0.0459
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0044 0.0466 0.0693
Mycobacterium tuberculosis Probable hydrolase 0.0043 0.0464 0.1356
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0044 0.0475 0.0473
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0012 0.0074 0.0074
Onchocerca volvulus Cathepsin L homolog 0.0016 0.0123 0.0424
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0039 0.0414 0.0412
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0438 0.5379 0.5379
Leishmania major cathepsin L-like protease 0.0016 0.0123 0.0118
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0007 0.0006 0.0003
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0023 0.0207 0.0597
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0012 0.0074 0.0074
Entamoeba histolytica cysteine protease, putative 0.0008 0.0026 0.003
Toxoplasma gondii ABC1 family protein 0.0043 0.0464 0.0689
Trichomonas vaginalis alpha-glucosidase, putative 0.0044 0.0466 0.1501
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0154 0.0149
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0044 0.0466 0.1501
Brugia malayi Bromodomain containing protein 0.0084 0.0968 0.0966
Loa Loa (eye worm) oxidoreductase 0.0007 0.0006 0.0006
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.069 0.0685
Schistosoma mansoni hypothetical protein 0.0035 0.0357 0.0357
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0019 0.016 0.0158
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0066 0.0739 0.0737
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0123 0.0397
Trypanosoma brucei ISWI complex protein 0.0017 0.0131 0.0126
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0029 0.0289 0.0426
Trypanosoma cruzi hypothetical protein, conserved 0.0044 0.0466 0.0461
Brugia malayi photoreceptor-specific nuclear receptor 0.0012 0.0074 0.0072
Echinococcus multilocularis isocitrate dehydrogenase 0.0019 0.016 0.0158
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0154 0.0497
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0016 0.0123 0.0121
Plasmodium vivax malate dehydrogenase, putative 0.054 0.6655 1
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0154 0.0152
Onchocerca volvulus Cathepsin F homolog 0.0016 0.0123 0.0424
Entamoeba histolytica cysteine protease, putative 0.0008 0.0026 0.003
Echinococcus granulosus short transient receptor potential channel 6 0.0078 0.0888 0.0887
Schistosoma mansoni ferritin 0.0008 0.0024 0.0024
Echinococcus granulosus short transient receptor potential channel 6 0.0078 0.0888 0.0887
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0007 0.0006 0.0006
Leishmania major cathepsin L-like protease 0.0062 0.069 0.0685
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0012 0.0074 0.0074
Plasmodium vivax SET domain protein, putative 0.0029 0.0289 0.0426
Schistosoma mansoni RAR-like nuclear receptor 0.0012 0.0074 0.0074
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0044 0.0475 0.0475
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0019 0.016 0.0154
Trypanosoma cruzi glycosomal malate dehydrogenase, putative 0.0249 0.3023 0.3019
Schistosoma mansoni aldehyde dehydrogenase 0.0067 0.0753 0.0753
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0029 0.0289 0.0289
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0012 0.0074 0.0074
Entamoeba histolytica hypothetical protein 0.0035 0.0357 0.0528
Trypanosoma cruzi cysteine peptidase, putative 0.0062 0.069 0.0685
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0019 0.0163 0.0237
Trichomonas vaginalis maltase-glucoamylase, putative 0.0044 0.0466 0.1501
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0043 0.0464 0.0464
Echinococcus multilocularis ecdysone induced protein 78C 0.0012 0.0074 0.0072
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0011 0.0057 0.0182
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0154 0.0149
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0012 0.0074 0.0072
Entamoeba histolytica cysteine protease, putative 0.0008 0.0026 0.003
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0207 0.0651
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.002 0.0166 0.0241
Mycobacterium ulcerans beta-lactamase 0.0043 0.0464 0.1479
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0026 0.025 0.025
Loa Loa (eye worm) hypothetical protein 0.0012 0.0074 0.0074
Schistosoma mansoni smad1 5 8 and 0.001 0.0044 0.0044
Echinococcus granulosus cathepsin L cysteine protease 0.0008 0.0026 0.0024
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0019 0.016 0.0232
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0012 0.0074 0.0072
Trichomonas vaginalis malate dehydrogenase, putative 0.0255 0.3105 1
Trichomonas vaginalis malate dehydrogenase, putative 0.0255 0.3105 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.069 0.0685
Entamoeba histolytica cysteine protease, putative 0.0008 0.0026 0.003
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0231 0.2799 0.2798
Brugia malayi MH1 domain containing protein 0.001 0.0044 0.0042
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.0154 0.0441
Entamoeba histolytica cysteine protease, putative 0.0008 0.0026 0.003
Schistosoma mansoni cpg binding protein 0.0031 0.0314 0.0314
Brugia malayi Isocitrate dehydrogenase 0.0019 0.016 0.0158
Brugia malayi F/Y-rich N-terminus family protein 0.0012 0.0067 0.0065
Schistosoma mansoni transient receptor potential channel 0.0117 0.1383 0.1383
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0123 0.0397
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0017 0.0135 0.0383
Mycobacterium tuberculosis Probable lipase LipD 0.0043 0.0464 0.1356
Echinococcus multilocularis short transient receptor potential channel 6 0.0078 0.0888 0.0887
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0012 0.0074 0.0072
Entamoeba histolytica cysteine proteinase, putative 0.0008 0.0026 0.003
Plasmodium vivax lactate dehydrogenase 0.054 0.6655 1
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0154 0.0149
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0123 0.0397
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0154 0.0154
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0008 0.0021 0.0019
Onchocerca volvulus 0.0012 0.0074 0.0246
Echinococcus granulosus carbonic anhydrase II 0.0808 1 1
Brugia malayi Glycosyl hydrolases family 31 protein 0.0197 0.2375 0.2373
Trichomonas vaginalis DNA helicase recq, putative 0.0029 0.0283 0.0912
Loa Loa (eye worm) RecQ helicase 0.0029 0.0283 0.0283
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0012 0.0074 0.0074
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0008 0.0026 0.002
Schistosoma mansoni cpg binding protein 0.0028 0.0268 0.0268
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0207 0.0205
Mycobacterium tuberculosis Probable esterase LipL 0.0043 0.0464 0.1356
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0056 0.0624 0.0618
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0019 0.016 0.0158
Brugia malayi Glycosyl hydrolases family 31 protein 0.0016 0.0124 0.0122
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0012 0.0071 0.0098
Loa Loa (eye worm) hypothetical protein 0.0017 0.0135 0.0135
Loa Loa (eye worm) hypothetical protein 0.0043 0.0464 0.0464
Echinococcus granulosus FTZ F1 alpha 0.0012 0.0074 0.0072
Echinococcus multilocularis transient receptor potential gamma protein 0.0117 0.1383 0.1381
Echinococcus granulosus mixed lineage leukemia protein mll 0.0008 0.0021 0.0019
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0044 0.0466 0.0693
Echinococcus multilocularis TGF beta signal transducer SmadC 0.001 0.0044 0.0042
Brugia malayi lactate dehydrogenase. 0.054 0.6655 0.6654
Echinococcus multilocularis FTZ F1 alpha 0.0012 0.0074 0.0072
Echinococcus granulosus cathepsin l cysteine peptidase 0.0016 0.0123 0.0121
Schistosoma mansoni retinoic acid receptor RXR 0.0012 0.0074 0.0074
Trypanosoma brucei glycosomal malate dehydrogenase 0.0249 0.3023 0.3019
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0012 0.0071 0.0098
Trypanosoma cruzi cysteine peptidase, putative 0.0062 0.069 0.0685
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0016 0.0123 0.0397
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.069 0.0685
Schistosoma mansoni alpha-glucosidase 0.0169 0.2033 0.2033
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0012 0.0074 0.0072
Echinococcus granulosus transient receptor potential gamma protein 0.0117 0.1383 0.1381
Entamoeba histolytica cysteine protease, putative 0.0008 0.0026 0.003
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0067 0.0753 0.0751
Brugia malayi Transient-receptor-potential like protein 0.0044 0.0465 0.0463
Brugia malayi PHD-finger family protein 0.0029 0.0282 0.028
Loa Loa (eye worm) hypothetical protein 0.0011 0.0057 0.0057
Brugia malayi beta-lactamase family protein 0.0043 0.0464 0.0462
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0207 0.0205
Echinococcus multilocularis neuropeptide receptor A26 0.0448 0.5514 0.5513
Echinococcus multilocularis bloom syndrome protein 0.0029 0.0283 0.0281
Brugia malayi Papain family cysteine protease containing protein 0.0008 0.0026 0.0024
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0012 0.0074 0.0072
Brugia malayi beta-lactamase 0.0043 0.0464 0.0462
Leishmania major cathepsin L-like protease 0.0016 0.0123 0.0118
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0012 0.0074 0.0072
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0008 0.0026 0.002
Mycobacterium tuberculosis Probable malate dehydrogenase Mdh 0.0255 0.3105 0.917
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0044 0.0475 0.0473
Loa Loa (eye worm) hypothetical protein 0.0006 0.0002 0.0002
Echinococcus granulosus cathepsin l1 0.0016 0.0123 0.0121
Schistosoma mansoni transient receptor potential channel 4 0.0117 0.1383 0.1383
Trypanosoma cruzi cysteine peptidase, putative 0.0008 0.0026 0.002
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0044 0.0466 0.0466
Trichomonas vaginalis D-aminoacylase, putative 0.0043 0.0464 0.1494
Toxoplasma gondii lactate dehydrogenase LDH2 0.054 0.6655 1
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0007 0.0006 0.0003
Loa Loa (eye worm) hypothetical protein 0.0006 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0017 0.0135 0.0135
Echinococcus granulosus dnaJ subfamily B 0.0395 0.4849 0.4848
Schistosoma mansoni alpha-glucosidase 0.0169 0.2033 0.2033
Loa Loa (eye worm) hypothetical protein 0.0017 0.0135 0.0135
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0012 0.0071 0.0069
Loa Loa (eye worm) hypothetical protein 0.0017 0.0135 0.0135
Schistosoma mansoni carbonic anhydrase-related 0.0438 0.5379 0.5379
Mycobacterium leprae conserved hypothetical protein 0.0043 0.0464 0.1479
Schistosoma mansoni thyroid hormone receptor 0.0164 0.197 0.197
Trichomonas vaginalis alpha-glucosidase, putative 0.0016 0.0124 0.0401
Trichomonas vaginalis malate dehydrogenase, putative 0.0137 0.1626 0.5238
Echinococcus granulosus neutral alpha glucosidase AB 0.0044 0.0466 0.0464
Schistosoma mansoni carbonic anhydrase-related 0.0438 0.5379 0.5379
Echinococcus granulosus Smad4 0.001 0.0044 0.0042
Onchocerca volvulus 0.0016 0.0123 0.0424
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0019 0.016 0.0154
Echinococcus granulosus polycomb protein SCMH1 0.0058 0.064 0.0638
Echinococcus multilocularis L lactate dehydrogenase 0.0309 0.3771 0.377
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0011 0.0057 0.0182
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.0207 0.0303
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0012 0.0071 0.0071
Trichomonas vaginalis D-aminoacylase, putative 0.0043 0.0464 0.1494
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0044 0.0475 0.0473
Schistosoma mansoni ferritin 0.0008 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.0146 0.1741 0.1741
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0012 0.0074 0.0072
Trypanosoma cruzi ISWI complex protein 0.0017 0.0131 0.0126

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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