Detailed information for compound 150181

Basic information

Technical information
  • TDR Targets ID: 150181
  • Name: benzyl N-[(2S,3S,5S)-5-[(4-amino-3-hydroxyben zoyl)amino]-3-hydroxy-1,6-diphenylhexan-2-yl] carbamate
  • MW: 553.648 | Formula: C33H35N3O5
  • H donors: 5 H acceptors: 4 LogP: 5.16 Rotable bonds: 15
    Rule of 5 violations (Lipinski): 2
  • SMILES: O=C(N[C@H]([C@H](C[C@@H](NC(=O)c1ccc(c(c1)O)N)Cc1ccccc1)O)Cc1ccccc1)OCc1ccccc1
  • InChi: 1S/C33H35N3O5/c34-28-17-16-26(20-30(28)37)32(39)35-27(18-23-10-4-1-5-11-23)21-31(38)29(19-24-12-6-2-7-13-24)36-33(40)41-22-25-14-8-3-9-15-25/h1-17,20,27,29,31,37-38H,18-19,21-22,34H2,(H,35,39)(H,36,40)/t27-,29-,31-/m0/s1
  • InChiKey: XRRUNPIXIAOGSC-JLHXZSQLSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • benzyl N-[(1S,2S,4S)-4-[(4-amino-3-hydroxy-benzoyl)amino]-1-benzyl-2-hydroxy-5-phenyl-pentyl]carbamate
  • N-[(1S,2S,4S)-4-[[(4-amino-3-hydroxyphenyl)-oxomethyl]amino]-1-benzyl-2-hydroxy-5-phenylpentyl]carbamic acid benzyl ester
  • phenylmethyl N-[(2S,3S,5S)-5-[(4-azanyl-3-hydroxy-phenyl)carbonylamino]-3-hydroxy-1,6-diphenyl-hexan-2-yl]carbamate
  • N-[(1S,2S,4S)-4-[(4-amino-3-hydroxy-benzoyl)amino]-1-benzyl-2-hydroxy-5-phenyl-pentyl]carbamic acid benzyl ester
  • phenylmethyl N-[(2S,3S,5S)-5-[(4-amino-3-hydroxybenzoyl)amino]-3-hydroxy-1,6-di(phenyl)hexan-2-yl]carbamate
  • phenylmethyl N-[(1S,2S,4S)-4-[(4-amino-3-hydroxy-benzoyl)amino]-2-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]carbamate
  • N-[(1S,2S,4S)-4-[[(4-amino-3-hydroxyphenyl)-oxomethyl]amino]-2-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]carbamic acid phenylmethyl ester
  • N-[(1S,2S,4S)-4-[(4-amino-3-hydroxy-benzoyl)amino]-1-(benzyl)-2-hydroxy-5-phenyl-pentyl]carbamic acid benzyl ester
  • phenylmethyl N-[(2S,3S,5S)-5-[(4-amino-3-hydroxy-phenyl)carbonylamino]-3-hydroxy-1,6-di(phenyl)hexan-2-yl]carbamate
  • 4NH2-3OH N-OHBu-BzNH, PhCH2 Cbz deriv.
  • AIDS-028162
  • AIDS028162
  • Benzyl N-[4-(4-amino-3-hydroxybenzamido)-1,3-dibenzylbutyl]carbamate

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 protease Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Schistosoma mansoni intracisternal A-particle retropepsin (A02 family) Get druggable targets OG5_131408 All targets in OG5_131408
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Candida albicans dethiobiotin synthetase Human immunodeficiency virus type 1 protease   99 aa 90 aa 22.2 %
Mycobacterium leprae Hypothetical protein Human immunodeficiency virus type 1 protease   99 aa 86 aa 27.9 %
Candida albicans dethiobiotin synthetase Human immunodeficiency virus type 1 protease   99 aa 90 aa 22.2 %
Echinococcus multilocularis Chromobox protein 3 Human immunodeficiency virus type 1 protease   99 aa 95 aa 28.4 %
Entamoeba histolytica retroviral aspartyl protease domain-containing protein Human immunodeficiency virus type 1 protease   99 aa 103 aa 31.1 %
Giardia lamblia DNA-directed RNA polymerase subunit D Human immunodeficiency virus type 1 protease   99 aa 90 aa 27.8 %
Trypanosoma brucei variant surface glycoprotein (VSG), putative Human immunodeficiency virus type 1 protease   99 aa 80 aa 27.5 %
Entamoeba histolytica retroviral aspartyl protease domain-containing protein Human immunodeficiency virus type 1 protease   99 aa 103 aa 31.1 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi inosine-5'-monophosphate dehydrogenase 0.0164 0.1016 0.3336
Loa Loa (eye worm) hypothetical protein 0.0018 0.0053 0.0173
Mycobacterium leprae Probable cystathionine beta-synthase CBS (Serine sulfhydrase) (Beta-thionase) (Hemoprotein H-450) 0.0023 0.009 0.0328
Trypanosoma brucei DNA polymerase kappa, putative 0.0034 0.0161 0.0604
Schistosoma mansoni cpg binding protein 0.0064 0.036 0.0358
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0016 0.0039 0.0038
Echinococcus granulosus AMP activated protein kinase gamma regulatory 0.0023 0.009 0.016
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0472 0.3043 1
Echinococcus multilocularis neuropeptide Y receptor 0.0472 0.3043 0.539
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0048 0.0252 0.0251
Loa Loa (eye worm) hypothetical protein 0.0472 0.3043 1
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0092 0.054 0.0956
Trypanosoma cruzi DNA polymerase kappa, putative 0.0034 0.0161 0.0615
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0014 0.0028 0.0092
Loa Loa (eye worm) hypothetical protein 0.0045 0.0235 0.0772
Brugia malayi Probable protein farnesyltransferase beta subunit, putative 0.0018 0.0053 0.0168
Schistosoma mansoni alpha(13)fucosyltransferase 0.0063 0.0348 0.0347
Echinococcus granulosus dnaJ subfamily B 0.0867 0.5646 1
Plasmodium falciparum protein farnesyltransferase subunit alpha 0.0282 0.1792 0.751
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0095 0.0348
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0016 0.0039 0.0069
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.001 0.0001 0.0005
Trichomonas vaginalis ap endonuclease, putative 0.0021 0.0077 0.0388
Trypanosoma brucei AMP-activated protein kinase, gamma regulatory subunit 0.0023 0.009 0.0325
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0018 0.0055 0.5355
Schistosoma mansoni cpg binding protein 0.0064 0.036 0.0358
Loa Loa (eye worm) GMP reductase 0.0164 0.1016 0.3339
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0019 0.0063 0.0112
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0024 0.0095 0.0348
Trypanosoma brucei DNA polymerase kappa, putative 0.0034 0.0161 0.0604
Echinococcus granulosus neuropeptide FF receptor 2 0.0472 0.3043 0.539
Schistosoma mansoni matrix metallopeptidase-7 (M10 family) 0.0046 0.0237 0.0235
Brugia malayi neuropeptide F receptor 0.0472 0.3043 1
Mycobacterium ulcerans DNA polymerase IV 0.0034 0.0161 0.0607
Echinococcus granulosus g protein coupled receptor 0.0472 0.3043 0.539
Loa Loa (eye worm) hypothetical protein 0.0028 0.0118 0.0389
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0041 0.0206 0.0787
Brugia malayi hypothetical protein 0.0472 0.3043 1
Loa Loa (eye worm) G-protein coupled receptor 0.0472 0.3043 1
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.001 0.0001 0.0003
Echinococcus granulosus SAM and MBT domain containing protein 0.0024 0.0096 0.017
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0048 0.0252 0.0251
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0472 0.3043 0.539
Entamoeba histolytica PH domain containing protein kinase, putative 0.0019 0.0061 0.0261
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0018 0.0057 0.0101
Loa Loa (eye worm) PXA domain-containing protein 0.0014 0.0028 0.0092
Schistosoma mansoni alpha(13)fucosyltransferase 0.0063 0.0348 0.0347
Giardia lamblia Prenyltransferase 0.0065 0.0367 0.2009
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0024 0.0095 0.0348
Echinococcus granulosus biogenic amine 5HT receptor 0.0472 0.3043 0.539
Trypanosoma cruzi protein farnesyltransferase alpha subunit, putative 0.0073 0.0417 0.1627
Trichomonas vaginalis protein farnesyltransferase beta subunit, putative 0.0018 0.0053 0.0249
Schistosoma mansoni alpha(13)fucosyltransferase 0.0063 0.0348 0.0347
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0021 0.0077 0.0285
Loa Loa (eye worm) hypothetical protein 0.0045 0.0232 0.0763
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0018 0.0057 0.0187
Loa Loa (eye worm) glutaminase 0.014 0.0856 0.2812
Schistosoma mansoni jumonji/arid domain-containing protein 0.0034 0.0157 0.0155
Brugia malayi ecdysteroid receptor 0.0018 0.0057 0.0183
Plasmodium falciparum geranylgeranyltransferase, putative 0.0018 0.0053 0.0161
Trypanosoma cruzi DNA polymerase kappa, putative 0.0034 0.0161 0.0615
Echinococcus multilocularis rhodopsin orphan GPCR 0.0472 0.3043 0.539
Leishmania major guanosine monophosphate reductase 0.0395 0.2536 1
Schistosoma mansoni alpha(13)fucosyltransferase 0.0011 0.0005 0.0004
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0013 0.0023 0.0071
Trichomonas vaginalis guanylate cyclase, putative 0.0013 0.002 0.0069
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0046 0.0238 0.0886
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0013 0.002 0.0069
Echinococcus multilocularis H(+):Cl() exchange transporter 3 0.0023 0.009 0.016
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0017 0.0045 0.0044
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0021 0.0077 0.0277
Echinococcus granulosus glycoprotein 3 alpha L fucosyltransferase 0.0027 0.0111 0.0196
Echinococcus multilocularis inositol monophosphatase 1 0.0046 0.0238 0.0421
Echinococcus multilocularis transcription factor Dp 1 0.0053 0.0285 0.0505
Brugia malayi MAP kinase sur-1 0.0026 0.0109 0.0352
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0021 0.0077 0.0285
Schistosoma mansoni family A2 unassigned peptidase (A02 family) 0.0278 0.1766 0.1764
Schistosoma mansoni serine/threonine protein kinase 0.0014 0.0031 0.0029
Echinococcus granulosus solute carrier family 5 0.0178 0.1109 0.1964
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0042 0.0216 0.0704
Echinococcus granulosus regulator of G protein signaling 3 0.0014 0.0028 0.0049
Loa Loa (eye worm) hypothetical protein 0.0472 0.3043 1
Schistosoma mansoni jumonji domain containing protein 0.003 0.0134 0.0132
Loa Loa (eye worm) G-protein coupled receptor 0.0472 0.3043 1
Echinococcus granulosus sodium:myo inositol cotransporter 0.0178 0.1109 0.1964
Loa Loa (eye worm) hypothetical protein 0.0472 0.3043 1
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0043 0.0217 0.0712
Echinococcus granulosus protein farnesyltransferase alpha subunit 0.0282 0.1792 0.3174
Echinococcus granulosus peptide allatostatin:somatostatin 0.0472 0.3043 0.539
Onchocerca volvulus 0.0024 0.0095 0.0309
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0039 0.0192 0.1
Loa Loa (eye worm) hypothetical protein 0.0472 0.3043 1
Schistosoma mansoni myosin xvIII 0.0472 0.3043 0.3042
Loa Loa (eye worm) hypothetical protein 0.0121 0.0732 0.2404
Trichomonas vaginalis helicase, putative 0.0014 0.0027 0.0104
Trypanosoma brucei unspecified product 0.0014 0.0029 0.0084
Echinococcus granulosus rhodopsin orphan GPCR 0.0472 0.3043 0.539
Schistosoma mansoni sex comb on midleg homolog 0.0024 0.0096 0.0095
Echinococcus multilocularis rhodopsin orphan GPCR 0.0472 0.3043 0.539
Echinococcus granulosus ankyrin repeat protein 0.0477 0.3081 0.5456
Loa Loa (eye worm) hypothetical protein 0.0472 0.3043 1
Echinococcus multilocularis glycoprotein 3 alpha L fucosyltransferase 0.0027 0.0111 0.0196
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0012 0.0015 0.0026
Echinococcus granulosus sodium:glucose cotransporter 2 0.0178 0.1109 0.1964
Schistosoma mansoni transient receptor potential cation channel subfamily A member 0.0477 0.3081 0.308
Leishmania major eukaryotic initiation factor 4a, putative 0.011 0.0657 0.2576
Trypanosoma brucei DNA polymerase eta, putative 0.0038 0.0186 0.0703
Loa Loa (eye worm) GABA receptor subunit 0.0043 0.0222 0.0729
Loa Loa (eye worm) hypothetical protein 0.0206 0.1295 0.4256
Onchocerca volvulus 0.0472 0.3043 1
Mycobacterium ulcerans glutaminase 0.014 0.0856 0.3356
Echinococcus multilocularis sex peptide receptor 0.0472 0.3043 0.539
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0095 0.0455
Loa Loa (eye worm) hypothetical protein 0.0043 0.0222 0.0729
Mycobacterium tuberculosis Halimadienyl diphosphate synthase 0.0018 0.0053 0.018
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0018 0.0057 0.0183
Schistosoma mansoni DEAD box ATP-dependent RNA helicase 0.011 0.0657 0.0656
Brugia malayi hypothetical protein 0.003 0.0134 0.0436
Echinococcus multilocularis neuropeptide receptor 0.0472 0.3043 0.539
Toxoplasma gondii CBS family protein 0.0023 0.009 0.03
Leishmania major protein kinase A catalytic subunit isoform 2 0.0019 0.0061 0.0219
Entamoeba histolytica 26S proteasome non-ATPase regulatory subunit 14, putative 0.0014 0.0031 0.0092
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0031 0.0142 0.0461
Trypanosoma brucei Protein prenyltransferase alpha subunit repeat, putative 0.0073 0.0417 0.1618
Onchocerca volvulus 0.0123 0.0746 0.2449
Schistosoma mansoni neuropeptide F-like receptor 0.0472 0.3043 0.3042
Onchocerca volvulus Bile acid receptor homolog 0.0018 0.0057 0.0183
Brugia malayi polk-prov protein 0.002 0.0067 0.0216
Echinococcus granulosus g protein coupled receptor 0.0472 0.3043 0.539
Trypanosoma cruzi chloride channel protein, putative 0.0023 0.009 0.0335
Echinococcus granulosus rhodopsin orphan GPCR 0.0472 0.3043 0.539
Echinococcus granulosus inosine 5' monophosphate dehydrogenase 2 0.0395 0.2536 0.4491
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0019 0.0063 0.0112
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0015 0.0037 0.0065
Echinococcus multilocularis dro:myosuppressin receptor 0.0472 0.3043 0.539
Trypanosoma brucei hypothetical protein, conserved 0.0073 0.0417 0.1618
Loa Loa (eye worm) hypothetical protein 0.0472 0.3043 1
Schistosoma mansoni serine/threonine protein kinase 0.0026 0.0109 0.0107
Schistosoma mansoni regulator of G protein signaling 0.0014 0.0028 0.0027
Leishmania major chloride channel protein, putative 0.0023 0.009 0.0335
Brugia malayi RE15519p 0.0472 0.3043 1
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0021 0.0077 0.0265
Mycobacterium ulcerans inosine 5-monophosphate dehydrogenase 0.0371 0.2381 0.9389
Loa Loa (eye worm) prenyltransferase and squalene oxidase repeat family protein 0.0018 0.0053 0.0173
Trypanosoma cruzi GMP reductase 0.0395 0.2536 1
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0156 0.0966 0.1711
Mycobacterium tuberculosis Conserved hypothetical protein 0.0021 0.0071 0.0253
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0048 0.0252 0.0447
Loa Loa (eye worm) hypothetical protein 0.0018 0.0057 0.0187
Plasmodium falciparum geranylgeranyl transferase type2 beta subunit, putative 0.0018 0.0053 0.0161
Trichomonas vaginalis CMGC family protein kinase 0.0026 0.0109 0.0564
Mycobacterium ulcerans aldehyde dehydrogenase 0.0031 0.014 0.0526
Echinococcus multilocularis dna polymerase kappa 0.0034 0.0161 0.0285
Brugia malayi Regulator of G protein signaling domain containing protein 0.0014 0.0028 0.0087
Onchocerca volvulus 0.0472 0.3043 1
Echinococcus granulosus voltage dependent calcium channel 0.0064 0.0357 0.0632
Echinococcus granulosus axis inhibition protein axin 0.0014 0.0028 0.0049
Trypanosoma brucei Protein prenyltransferase alpha subunit repeat, putative 0.0073 0.0417 0.1618
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0018 0.0057 0.0187
Loa Loa (eye worm) latrophilin receptor protein 2 0.0015 0.0037 0.0121
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.001 0.0001 0.0005
Schistosoma mansoni hypothetical protein 0.0472 0.3043 0.3042
Brugia malayi sulfakinin receptor protein 0.0472 0.3043 1
Brugia malayi Serotonin receptor 0.0472 0.3043 1
Loa Loa (eye worm) hypothetical protein 0.0018 0.0057 0.0187
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0046 0.0238 0.0919
Onchocerca volvulus Protein ultraspiracle homolog 0.0018 0.0057 0.0183
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0018 0.0057 0.0101
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0019 0.0061 0.0108
Loa Loa (eye worm) mbt repeat family protein 0.0024 0.0096 0.0316
Trypanosoma brucei DNA polymerase kappa, putative 0.0034 0.0161 0.0604
Treponema pallidum fructose-bisphosphate aldolase 0.0149 0.0919 1
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0024 0.0093 0.0334
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0016 0.0039 0.0069
Loa Loa (eye worm) IMP dehydrogenase 1 0.0395 0.2536 0.8332
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.001 0.0001 0.0002
Schistosoma mansoni aryl hydrocarbon receptor 0.0049 0.0261 0.026
Loa Loa (eye worm) hypothetical protein 0.0042 0.0216 0.0708
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.001 0.0001 0.0003
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0031 0.0142 0.0532
Echinococcus granulosus fmrfamide receptor 0.0472 0.3043 0.539
Loa Loa (eye worm) hypothetical protein 0.0013 0.002 0.0067
Schistosoma mansoni protein farnesyltransferase alpha subunit 0.0282 0.1792 0.1791
Echinococcus granulosus protein prenyltransferase alpha subunit 0.0073 0.0417 0.0739
Loa Loa (eye worm) hypothetical protein 0.0023 0.009 0.0296
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0149 0.0919 0.509
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0026 0.0109 0.0409
Trypanosoma cruzi GMP reductase 0.0395 0.2536 1
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0005
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0064 0.0357 0.0632
Echinococcus granulosus aryl hydrocarbon receptor 0.0013 0.002 0.0036
Loa Loa (eye worm) hypothetical protein 0.0014 0.0028 0.0092
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0039 0.0192 0.0739
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0073 0.0416 0.1618
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0015 0.0037 0.0065
Entamoeba histolytica hypothetical protein 0.0018 0.0057 0.0238
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0005
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0018 0.0057 0.0183
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0064 0.0359 0.0636
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0018 0.0057 0.0187
Echinococcus multilocularis expressed protein 0.0273 0.1731 0.3066
Loa Loa (eye worm) RGS-3 protein 0.0014 0.0028 0.0092
Brugia malayi glutaminase DH11.1 0.014 0.0856 0.2808
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0005
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0046 0.0238 0.1287
Schistosoma mansoni sodium/solute symporter 0.0045 0.0235 0.0234
Brugia malayi PXA domain containing protein 0.0014 0.0028 0.0087
Trypanosoma brucei DNA polymerase kappa, putative 0.0024 0.0093 0.0338
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0012 0.0014 0.0029
Echinococcus multilocularis beta adrenergic receptor kinase 0.0014 0.0031 0.0055
Echinococcus multilocularis neuropeptide receptor A26 0.0472 0.3043 0.539
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0015 0.0037 0.0117
Schistosoma mansoni ets-related 0.015 0.0925 0.0923
Plasmodium vivax inosine-5'-monophosphate dehydrogenase, putative 0.0371 0.2381 1
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0019 0.0061 0.0219
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0046 0.0238 0.1256
Echinococcus granulosus eukaryotic initiation factor 4A III 0.011 0.0657 0.1164
Loa Loa (eye worm) hypothetical protein 0.0012 0.0015 0.0049
Schistosoma mansoni inositol transporter 0.0178 0.1109 0.1107
Onchocerca volvulus 0.0472 0.3043 1
Trichomonas vaginalis inositol monophosphatase, putative 0.0046 0.0238 0.1287
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0031 0.0142 0.014
Schistosoma mansoni geranylgeranyl transferase type II beta subunit 0.0018 0.0053 0.0051
Echinococcus multilocularis alpha(13)fucosyltransferase 0.0027 0.0111 0.0196
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0031 0.014 0.0248
Trypanosoma brucei DNA polymerase kappa, putative 0.0018 0.0051 0.0171
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0048 0.0252 0.0251
Echinococcus granulosus nAChR subunit 0.001 0.0001 0.0003
Brugia malayi 26S proteasome regulatory subunit rpn11 0.0014 0.0031 0.0097
Schistosoma mansoni retinoic acid receptor RXR 0.0018 0.0057 0.0056
Trypanosoma brucei PAB1-binding protein , putative 0.003 0.0134 0.0498
Echinococcus multilocularis geranylgeranyl transferase type I beta subunit 0.0018 0.0053 0.0093
Schistosoma mansoni regulator of G protein signaling 0.0014 0.0028 0.0027
Trypanosoma brucei DNA polymerase kappa, putative 0.0034 0.0161 0.0604
Loa Loa (eye worm) hypothetical protein 0.0045 0.0235 0.0772
Schistosoma mansoni hypothetical protein 0.0211 0.1326 0.1325
Leishmania major protein kinase A catalytic subunit isoform 1 0.0019 0.0061 0.0219
Loa Loa (eye worm) hypothetical protein 0.0472 0.3043 1
Echinococcus multilocularis axis inhibition protein axin 0.0014 0.0028 0.0049
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0027 0.0104
Loa Loa (eye worm) hypothetical protein 0.0472 0.3043 1
Loa Loa (eye worm) hypothetical protein 0.0014 0.0028 0.0092
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0024 0.0096 0.0095
Echinococcus multilocularis SNF4:AMP activated protein kinase gamma subunit 0.0023 0.009 0.016
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0092 0.054 0.2112
Loa Loa (eye worm) hypoxia-induced factor 1 0.0153 0.0943 0.3099
Loa Loa (eye worm) hypothetical protein 0.0018 0.0057 0.0187
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0092 0.054 0.1774
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0018 0.0055 0.0189
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0039 0.0192 0.0739
Echinococcus multilocularis solute carrier family 5 0.0178 0.1109 0.1964
Onchocerca volvulus Putative GMP reductase 0.0164 0.1016 0.3336
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0048 0.0252 0.0447
Schistosoma mansoni cellular tumor antigen P53 0.0045 0.0231 0.023
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0013 0.002 0.0069
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0042 0.0216 0.0214
Brugia malayi Tachykinin-like peptides receptor 99D 0.0472 0.3043 1
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0014 0.0028 0.0027
Trypanosoma cruzi DNA polymerase eta, putative 0.0024 0.0092 0.0344
Loa Loa (eye worm) MBCTL1 0.0028 0.0118 0.0389
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0018 0.0057 0.0101
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.001 0.0001 0.0003
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0017 0.0045 0.008
Trichomonas vaginalis DNA polymerase eta, putative 0.0034 0.0161 0.0856
Onchocerca volvulus Alpha 1,3 fucosyltransferase homolog 0.0027 0.0111 0.036
Leishmania major phosphopantetheinyl transferase-like protein 0.0012 0.0014 0.0036
Brugia malayi Pre-SET motif family protein 0.0108 0.0645 0.2115
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0095 0.0356
Echinococcus multilocularis allatostatin A receptor 0.0472 0.3043 0.539
Schistosoma mansoni myelin transcription factor 1 myt1 0.0028 0.0118 0.0117
Loa Loa (eye worm) hypothetical protein 0.0018 0.0055 0.0181
Onchocerca volvulus 0.0472 0.3043 1
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0472 0.3043 0.539
Schistosoma mansoni hypothetical protein 0.0015 0.0037 0.0035
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0019 0.0061 0.0184
Schistosoma mansoni AMP-activated protein kinase gamma regulatory subunit 0.0023 0.009 0.0089
Trichomonas vaginalis rotamase, putative 0.0039 0.0192 0.1032
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0031 0.0142 0.0532
Plasmodium vivax conserved Plasmodium protein, unknown function 0.0048 0.025 0.0994
Entamoeba histolytica Rab geranylgeranyltransferase beta subunit, putative 0.0018 0.0053 0.0215
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0024 0.0095 0.0348
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0472 0.3043 1
Mycobacterium leprae Probable inosine-5'-monophosphate dehydrogenase GuaB2 (IMP dehydrogenase) (IMPDH) (IMPD) 0.0395 0.2536 1
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0024 0.0093 0.0341
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0472 0.3043 0.3042
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0018 0.0057 0.0183
Brugia malayi Protein prenyltransferase alpha subunit repeat containing protein 0.0282 0.1792 0.5886
Giardia lamblia Translation initiation factor eIF-4A, putative 0.011 0.0657 0.3638
Trypanosoma brucei lanosterol synthase 0.0018 0.0053 0.0176
Plasmodium vivax farnesyltransferase beta subunit, putative 0.0065 0.0367 0.1488
Echinococcus multilocularis geranylgeranyl transferase type 2 subunit alpha 0.0073 0.0417 0.0739
Echinococcus multilocularis geminin 0.0211 0.1326 0.2348
Trypanosoma cruzi PAB1-binding protein , putative 0.003 0.0134 0.0509
Echinococcus multilocularis g protein coupled receptor 0.0472 0.3043 0.539
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0018 0.0057 0.0101
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0017 0.0045 0.008
Loa Loa (eye worm) hypothetical protein 0.0472 0.3043 1
Brugia malayi hypothetical protein 0.0206 0.1295 0.4253
Echinococcus multilocularis glycoprotein 3 alpha L fucosyltransferase 0.0027 0.0111 0.0196
Treponema pallidum Mg2+ transport protein (mgtE) 0.0023 0.009 0.0837
Brugia malayi CXXC zinc finger family protein 0.0061 0.0337 0.1102
Loa Loa (eye worm) hypothetical protein 0.0472 0.3043 1
Entamoeba histolytica hypothetical protein 0.0014 0.0028 0.0076
Plasmodium falciparum eukaryotic initiation factor 4A 0.011 0.0657 0.2716
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.003 0.0134 0.0237
Echinococcus granulosus G protein coupled receptor 139 0.0472 0.3043 0.539
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0005
Brugia malayi hypothetical protein 0.0121 0.0732 0.24
Loa Loa (eye worm) matrixin family protein 0.0058 0.032 0.1051
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0149 0.0919 0.5108
Echinococcus multilocularis GA binding protein alpha chain 0.0049 0.0262 0.0463
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0046 0.0238 0.1287
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0018 0.0057 0.0056
Brugia malayi latrophilin 2 splice variant baaae 0.0033 0.0154 0.0503
Trypanosoma cruzi hypothetical protein, conserved 0.0012 0.0015 0.0039
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0046 0.0238 0.0919
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0472 0.3043 0.3042
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0021 0.0077 0.0274
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0472 0.3043 1
Echinococcus multilocularis ecdysone induced protein 78C 0.0018 0.0057 0.0101
Trypanosoma cruzi inosine-5'-monophosphate dehydrogenase, putative 0.0395 0.2536 1
Echinococcus granulosus glycoprotein 3 alpha L fucosyltransferase 0.0027 0.0111 0.0196
Trypanosoma cruzi Domain of unknown function DUF21, putative 0.0023 0.009 0.0335
Echinococcus multilocularis L aminoadipate semialdehyde 0.0042 0.0216 0.0382
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0019 0.0061 0.0208
Brugia malayi follicle stimulating hormone receptor 0.0472 0.3043 1
Onchocerca volvulus 0.0206 0.1295 0.4253
Trypanosoma brucei unspecified product 0.0014 0.0029 0.0084
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0472 0.3043 0.539
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0005
Echinococcus granulosus polycomb protein SCMH1 0.0024 0.0096 0.017
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0095 0.0348
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0048 0.0163
Echinococcus granulosus geranylgeranyl transferase type 2 subunit alpha 0.0073 0.0417 0.0739
Mycobacterium tuberculosis Probable conserved transmembrane protein 0.0023 0.009 0.0328
Schistosoma mansoni hypothetical protein 0.0015 0.0037 0.0035
Echinococcus multilocularis glycoprotein 3 alpha L fucosyltransferase 0.0027 0.0111 0.0196
Echinococcus granulosus tm gpcr rhodopsin 0.0472 0.3043 0.539
Echinococcus multilocularis inosine 5' monophosphate dehydrogenase 2 0.0395 0.2536 0.4491
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0018 0.0057 0.0183
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0046 0.0238 0.0908
Echinococcus multilocularis aryl hydrocarbon receptor 0.0013 0.002 0.0036
Schistosoma mansoni inosine-5-monophosphate dehydrogenase 0.0395 0.2536 0.2535
Brugia malayi Hypothetical 35.8 kDa protein F37A4.5 in chromosome III 0.0014 0.0031 0.0097
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0024 0.0095 0.0348
Loa Loa (eye worm) hypothetical protein 0.0472 0.3043 1
Schistosoma mansoni protein farnesyltransferase subunit beta 0.0065 0.0367 0.0365
Echinococcus multilocularis regulator of G protein signaling 7 0.0014 0.0028 0.0049
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0014 0.0028 0.0027
Toxoplasma gondii transporter, solute:sodium symporter (SSS) family protein 0.0045 0.0235 0.0875
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0014 0.0031 0.0097
Schistosoma mansoni rotamase 0.004 0.0198 0.0197
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0043 0.0217 0.0384
Schistosoma mansoni regulator of G protein signaling 0.0014 0.0028 0.0027
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0018 0.0057 0.0101
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0092 0.054 0.0956
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0049 0.0255 0.0835
Schistosoma mansoni cpg binding protein 0.0061 0.0337 0.0335
Mycobacterium tuberculosis Probable cold-shock DeaD-box protein A homolog DeaD (ATP-dependent RNA helicase dead homolog) 0.011 0.0657 0.2571
Mycobacterium ulcerans cystathionine beta-synthase 0.0023 0.009 0.0328
Brugia malayi exodeoxyribonuclease III family protein 0.0021 0.0077 0.0249
Schistosoma mansoni alpha(13)fucosyltransferase 0.0011 0.0005 0.0004
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0018 0.0057 0.0187
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.001 0.0001 0.0003
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0013 0.002 0.0069
Toxoplasma gondii prenyltransferase and squalene oxidase repeat-containing protein 0.0065 0.0367 0.1397
Plasmodium vivax SET domain protein, putative 0.0017 0.0045 0.0129
Loa Loa (eye worm) hypothetical protein 0.0472 0.3043 1
Loa Loa (eye worm) hypothetical protein 0.0472 0.3043 1
Brugia malayi Pre-SET motif family protein 0.0017 0.0045 0.0143
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0027 0.0104
Schistosoma mansoni vesicular amine transporter 0.0011 0.0009 0.0007
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0472 0.3043 0.3042
Loa Loa (eye worm) hypothetical protein 0.002 0.0067 0.0221
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0031 0.014 0.0526
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0018 0.0055 0.0189
Echinococcus multilocularis regulator of G protein signaling 3 0.0014 0.0028 0.0049
Echinococcus granulosus Regulator of G protein signaling 20 0.0014 0.0028 0.0049
Trypanosoma brucei unspecified product 0.0031 0.0139 0.0516
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0019 0.0058 0.0102
Brugia malayi AKH receptor 0.0472 0.3043 1
Schistosoma mansoni gabp alpha 0.0049 0.0262 0.026
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0028 0.0111
Echinococcus multilocularis glycoprotein 3 alpha L fucosyltransferase 0.0027 0.0111 0.0196
Loa Loa (eye worm) hypothetical protein 0.0018 0.0057 0.0187
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0149 0.0919 0.5108
Echinococcus multilocularis rhodopsin orphan GPCR 0.0472 0.3043 0.539
Echinococcus multilocularis tissue type plasminogen activator 0.0012 0.0015 0.0027
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0472 0.3043 0.3042
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0092 0.054 0.2112
Echinococcus multilocularis tumor protein p63 0.0306 0.1954 0.3461
Echinococcus granulosus biogenic amine 5HT receptor 0.0472 0.3043 0.539
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0046 0.0238 0.0919
Echinococcus multilocularis voltage dependent calcium channel 0.0064 0.0357 0.0632
Schistosoma mansoni neuropeptide receptor 0.0472 0.3043 0.3042
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0031 0.0142 0.0532
Schistosoma mansoni inositol monophosphatase 0.0046 0.0238 0.0236
Loa Loa (eye worm) loechrig isoform VII 0.0023 0.009 0.0296
Loa Loa (eye worm) hypothetical protein 0.0024 0.0093 0.0304
Trypanosoma cruzi protein farnesyltransferase, putative 0.0065 0.0367 0.1428
Schistosoma mansoni neuropeptide F-like receptor 0.0472 0.3043 0.3042
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0016 0.0039 0.0069
Brugia malayi Melatonin receptor type 1A 0.0472 0.3043 1
Echinococcus granulosus tm gpcr rhodopsin 0.0472 0.3043 0.539
Schistosoma mansoni geranylgeranyl transferase type I beta subunit 0.0018 0.0053 0.0051
Echinococcus multilocularis cpg binding protein 0.0064 0.036 0.0637
Chlamydia trachomatis GutQ/KpsF family sugar-phosphate isomerase 0.0023 0.009 1
Loa Loa (eye worm) TAR-binding protein 0.0062 0.0342 0.1124
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0014 0.0031 0.0102
Plasmodium falciparum protein farnesyltransferase subunit beta 0.0065 0.0367 0.1488
Brugia malayi Nuclear hormone receptor-like 1 0.0018 0.0057 0.0183
Schistosoma mansoni eyes absent homolog 0.0045 0.0232 0.0231
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0149 0.0919 0.5108
Loa Loa (eye worm) hypothetical protein 0.0024 0.0095 0.0313
Loa Loa (eye worm) proteasome 26S subunit 0.0011 0.0008 0.0027
Trichomonas vaginalis guanylate cyclase, putative 0.0013 0.002 0.0069
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0019 0.0061 0.0108
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0472 0.3043 1
Leishmania major hypothetical protein, conserved 0.003 0.0134 0.0509
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0005
Brugia malayi hypothetical protein 0.0226 0.1426 0.4684
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0018 0.0057 0.0101
Toxoplasma gondii kringle domain-containing protein 0.0012 0.0015 0.0002
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0472 0.3043 0.539
Toxoplasma gondii CBS domain-containing protein 0.0023 0.009 0.03
Wolbachia endosymbiont of Brugia malayi Mg/Co/Ni transporter MgtE 0.0023 0.009 0.03
Brugia malayi loechrig isoform VII 0.0023 0.009 0.0292
Brugia malayi G-protein coupled receptor 0.0472 0.3043 1
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0064 0.0359 0.0636
Echinococcus granulosus receptor type tyrosine protein phosphatase zeta 0.0124 0.0753 0.1333
Onchocerca volvulus 0.0061 0.0337 0.1102
Echinococcus multilocularis neuropeptide FF receptor 2 0.0472 0.3043 0.539
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0027 0.0116 0.038
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0043 0.0217 0.0708
Loa Loa (eye worm) hypothetical protein 0.0018 0.0055 0.0181
Schistosoma mansoni amine GPCR 0.0472 0.3043 0.3042
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0011 0.0011 0.002
Loa Loa (eye worm) hypothetical protein 0.0472 0.3043 1
Brugia malayi TAR-binding protein 0.0062 0.0342 0.112
Echinococcus granulosus glycoprotein 3 alpha L fucosyltransferase 0.0027 0.0111 0.0196
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0062 0.0342 0.1124
Schistosoma mansoni alpha 13/4 fucosyltransferase Lewis 1 0.0036 0.0173 0.0172
Echinococcus multilocularis neuropeptides capa receptor 0.0472 0.3043 0.539
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0472 0.3043 0.3042
Brugia malayi F/Y-rich N-terminus family protein 0.0019 0.0062 0.0199
Brugia malayi Inositol-1 0.0046 0.0238 0.0777
Schistosoma mansoni inositol transporter 0.0178 0.1109 0.1107
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0472 0.3043 0.3042
Echinococcus multilocularis Transcription initiation factor TFIID subunit 0.0016 0.0041 0.0073
Onchocerca volvulus 0.0023 0.009 0.0292
Leishmania major farnesyltransferase beta subunit 0.0065 0.0367 0.1428
Schistosoma mansoni z-protein (S1r protein) 0.0014 0.0028 0.0027
Echinococcus multilocularis Protein lozenge 0.0028 0.0123 0.0217
Echinococcus granulosus rhodopsin orphan GPCR 0.0472 0.3043 0.539
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0005
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0021 0.0077 0.0137
Brugia malayi hypothetical protein 0.0472 0.3043 1
Echinococcus multilocularis serotonin receptor 0.0472 0.3043 0.539
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0013 0.002 0.006
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0025 0.0098 0.0318
Schistosoma mansoni neuropeptide receptor 0.0472 0.3043 0.3042
Brugia malayi Protein kinase domain containing protein 0.0013 0.0019 0.0057
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0028 0.0118 0.021
Brugia malayi Ets-domain containing protein 0.0049 0.0262 0.0855
Plasmodium vivax acyl-CoA synthetase, putative 0.0018 0.0055 0.0171
Echinococcus multilocularis G-protein coupled receptor, putative 0.0472 0.3043 0.539
Schistosoma mansoni hypothetical protein 0.0015 0.0037 0.0035
Trichomonas vaginalis CMGC family protein kinase 0.0026 0.0109 0.0564
Echinococcus granulosus lysine specific demethylase 5A 0.0034 0.0157 0.0277
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0073 0.0417 0.2292
Trypanosoma brucei DNA polymerase kappa, putative 0.0018 0.0051 0.0171
Mycobacterium ulcerans aldehyde dehydrogenase 0.0031 0.014 0.0526
Trypanosoma cruzi Eukaryotic initiation factor 4A-1 0.011 0.0657 0.2576
Brugia malayi chloride channel protein 7 0.0023 0.009 0.0292
Plasmodium falciparum ataxin-2 like protein, putative 0.003 0.0134 0.0505
Schistosoma mansoni biogenic amine receptor 0.0472 0.3043 0.3042
Mycobacterium tuberculosis Hypoxic response protein 1 Hrp1 0.0023 0.009 0.0328
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0028 0.0111
Loa Loa (eye worm) hypothetical protein 0.0018 0.0057 0.0187
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0013 0.002 0.006
Schistosoma mansoni opsin-like receptor 0.0472 0.3043 0.3042
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0012 0.0015 0.0002
Toxoplasma gondii transporter, cation channel family protein 0.0024 0.0093 0.031
Brugia malayi ORL1-like opioid receptor 0.0472 0.3043 1
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0472 0.3043 0.3042
Loa Loa (eye worm) ACC-1 protein 0.001 0.0001 0.0005
Echinococcus multilocularis neuropeptide receptor 0.0472 0.3043 0.539
Onchocerca volvulus Neuropeptide F receptor homolog 0.0472 0.3043 1
Plasmodium falciparum geranylgeranyl transferase type-2 subunit alpha, putative 0.0073 0.0417 0.1701
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0064 0.0357 0.0632
Echinococcus granulosus neuropeptide s receptor 0.0472 0.3043 0.539
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0018 0.0057 0.0183
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0018 0.0057 0.0101
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0095 0.0356
Loa Loa (eye worm) fucosyl transferase 0.0063 0.0348 0.1144
Trypanosoma cruzi chloride channel protein, putative 0.0023 0.009 0.0335
Leishmania major proteasome regulatory non-ATP-ase subunit 11, putative,19S proteasome regulatory subunit, Metallo- peptidase, Clan MP, Family M6 0.0011 0.0008 0.0011
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0472 0.3043 1
Echinococcus granulosus mitogen activated protein kinase 3 0.0026 0.0109 0.0192
Echinococcus granulosus survival motor neuron protein 1 0.0121 0.0732 0.1296
Echinococcus granulosus neuropeptide receptor 0.0472 0.3043 0.539
Leishmania major protein kinase, putative 0.0013 0.0023 0.0071
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0012 0.0015 0.0026
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0092 0.054 0.2112
Schistosoma mansoni hypothetical protein 0.0013 0.0025 0.0023
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0031 0.014 0.0533
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0031 0.014 0.0248
Leishmania major CBS domain protein, conserved 0.0023 0.009 0.0335
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0014 0.0028 0.0049
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0017 0.0045 0.0121
Brugia malayi Calcitonin receptor-like protein seb-1 0.0049 0.0255 0.0835
Echinococcus granulosus transient receptor potential cation channel 0.0482 0.3113 0.5514
Echinococcus multilocularis glycine receptor subunit beta 0.0048 0.0252 0.0447
Trypanosoma brucei DNA polymerase IV, putative 0.0034 0.0161 0.0604
Brugia malayi G protein-coupled receptor 0.0472 0.3043 1
Trypanosoma cruzi inosine-5'-monophosphate dehydrogenase, putative 0.0395 0.2536 1
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0472 0.3043 0.539
Loa Loa (eye worm) TYRA-2 protein 0.0472 0.3043 1
Brugia malayi putative neuropeptide receptor 0.0472 0.3043 1
Entamoeba histolytica Rab geranylgeranyltransferase alpha subunit, putative 0.0073 0.0417 0.2265
Schistosoma mansoni chloride channel protein 0.0023 0.009 0.0089
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0017 0.0045 0.0044
Brugia malayi PXA domain containing protein 0.0014 0.0028 0.0087
Echinococcus granulosus beta-adrenergic receptor kinase 0.0014 0.0031 0.0055
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0028 0.0111
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0472 0.3043 0.539
Trypanosoma brucei DNA polymerase kappa, putative 0.0034 0.0161 0.0604
Brugia malayi ImpB/MucB/SamB family protein 0.0021 0.0071 0.023
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.004 0.0198 0.0647
Schistosoma mansoni amine GPCR 0.0472 0.3043 0.3042
Mycobacterium ulcerans transcriptional regulator 0.0023 0.009 0.0328
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0024 0.0093 0.0345
Leishmania major protein kinase, putative 0.0013 0.0023 0.0071
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0018 0.0057 0.0187
Echinococcus multilocularis thyroid hormone receptor alpha 0.0083 0.0481 0.0851
Echinococcus multilocularis GPCR, family 2 0.0015 0.0037 0.0065
Loa Loa (eye worm) hypothetical protein 0.0472 0.3043 1
Onchocerca volvulus 0.0226 0.1426 0.4684
Giardia lamblia Kinase, CMGC MAPK 0.0026 0.0109 0.0564
Loa Loa (eye worm) hypothetical protein 0.0472 0.3043 1
Schistosoma mansoni alpha-1 adrenergic receptor 0.0472 0.3043 0.3042
Schistosoma mansoni jumonji/arid domain-containing protein 0.0034 0.0157 0.0155
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0472 0.3043 0.3042
Mycobacterium tuberculosis Probable inosine-5'-monophosphate dehydrogenase GuaB3 (imp dehydrogenase) (inosinic acid dehydrogenase) (inosinate dehydrogenase 0.0207 0.1301 0.5116
Leishmania major chloride channel protein, putative 0.0023 0.009 0.0335
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0005
Echinococcus granulosus geminin 0.0211 0.1326 0.2348
Brugia malayi ImpB/MucB/SamB family protein 0.0038 0.0186 0.0606
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0472 0.3043 0.539
Schistosoma mansoni AMP-activated protein kinase gamma regulatory subunit 0.0023 0.009 0.0089
Echinococcus granulosus neuropeptides capa receptor 0.0472 0.3043 0.539
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0027 0.0104
Echinococcus multilocularis SAM and MBT domain containing protein 0.0024 0.0096 0.017
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0019 0.0061 0.0108
Onchocerca volvulus 0.0018 0.0057 0.0183
Toxoplasma gondii eukaryotic initiation factor-4A, putative 0.011 0.0657 0.2549
Mycobacterium ulcerans aldehyde dehydrogenase 0.0031 0.014 0.0526
Giardia lamblia Hypothetical protein 0.0023 0.009 0.046
Echinococcus multilocularis serotonin receptor 0.0472 0.3043 0.539
Echinococcus multilocularis H(+):Cl() exchange transporter 7 0.0023 0.009 0.016
Echinococcus granulosus allatostatin A receptor 0.0472 0.3043 0.539
Brugia malayi Dopamine receptor protein 2 0.0472 0.3043 1
Schistosoma mansoni transcription factor LCR-F1 0.0018 0.0057 0.0055
Trypanosoma brucei Eukaryotic initiation factor 4A-1 0.011 0.0657 0.2568
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0021 0.0077 0.0277
Treponema pallidum hemolysin (tlyC) 0.0023 0.009 0.0837
Onchocerca volvulus 0.0037 0.0177 0.0576
Mycobacterium ulcerans hypothetical protein 0.0023 0.009 0.0328
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0019 0.0061 0.0108
Schistosoma mansoni thyroid hormone receptor 0.0083 0.0481 0.0479
Brugia malayi regulator of G-protein signaling rgs-7 0.0014 0.0028 0.0087
Loa Loa (eye worm) hypothetical protein 0.0014 0.0028 0.0092
Schistosoma mansoni aldehyde dehydrogenase 0.0031 0.014 0.0139
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0012 0.0014 0.0029
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0048 0.0163
Entamoeba histolytica protein farnesyltransferase alpha subunit, putative 0.0282 0.1792 1
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0021 0.0077 0.0265
Toxoplasma gondii chloride transporter, chloride channel (ClC) family protein 0.0023 0.009 0.03
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0472 0.3043 0.3042
Schistosoma mansoni aldehyde dehydrogenase 0.0031 0.014 0.0139
Trypanosoma cruzi lanosterol synthase, putative 0.0018 0.0053 0.0187
Echinococcus multilocularis rhodopsin orphan GPCR 0.0472 0.3043 0.539
Echinococcus multilocularis FTZ F1 alpha 0.0018 0.0057 0.0101
Echinococcus granulosus orexin receptor type 2 0.0472 0.3043 0.539
Schistosoma mansoni alpha(13)fucosyltransferase 0.0011 0.0005 0.0004
Loa Loa (eye worm) hypothetical protein 0.0472 0.3043 1
Brugia malayi hypoxia-induced factor 1 0.0153 0.0943 0.3095
Trichomonas vaginalis set domain proteins, putative 0.0122 0.0742 0.4112
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0064 0.0357 0.0632
Toxoplasma gondii prenyltransferase and squalene oxidase repeat-containing protein 0.0018 0.0053 0.0151
Trichomonas vaginalis glutaminase, putative 0.014 0.0856 0.4751
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0028 0.0111
Plasmodium vivax geranylgeranyl transferase type2 beta subunit, putative 0.0018 0.0053 0.0161
Echinococcus granulosus dna polymerase eta 0.0038 0.0186 0.0329
Echinococcus multilocularis transient receptor potential cation channel 0.0483 0.3118 0.5522
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0026 0.0109 0.0409
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0149 0.0919 0.5108
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0026 0.0109 0.0374
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0027 0.0104
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.004 0.0198 0.0652
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0018 0.0057 0.0101
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0014 0.0028 0.0111
Echinococcus multilocularis nAChR subunit 0.001 0.0001 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0028 0.0111
Echinococcus granulosus tar DNA binding protein 0.0062 0.0342 0.0606
Mycobacterium leprae Probable inosine-5'-monophosphate dehydrogenase GuaB3 (IMP dehydrogenase 2) (inosinic acid dehydrogenase) (inosinate dehydrogena 0.0207 0.1301 0.5116
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0014 0.0027 0.0104
Echinococcus multilocularis glycoprotein 3 alpha L fucosyltransferase 0.0027 0.0111 0.0196
Loa Loa (eye worm) hypothetical protein 0.0018 0.0057 0.0187
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.0012 0.0016 0.003
Brugia malayi CLC chloride channel protein 0.0023 0.009 0.0292
Toxoplasma gondii histone lysine methyltransferase SET1 0.0116 0.0699 0.2715
Plasmodium vivax 26S proteasome regulatory subunit RPN11, putative 0.0014 0.0031 0.0069
Mycobacterium ulcerans hypothetical protein 0.0023 0.009 0.0328
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0041 0.0206 0.0787
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0018 0.0057 0.0101
Loa Loa (eye worm) chloride channel protein 7 0.0023 0.009 0.0296
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0012 0.0015 0.0013
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0027 0.0104
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.001 0.0001 0.0003
Brugia malayi jmjC domain containing protein 0.0034 0.0157 0.051
Loa Loa (eye worm) prenyltransferase alpha subunit repeat containing protein 0.0282 0.1792 0.5888
Schistosoma mansoni geranylgeranyl transferase type I beta subunit 0.0018 0.0053 0.0051
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0095 0.0309
Mycobacterium ulcerans putative regulatory protein 0.0037 0.0177 0.067
Loa Loa (eye worm) hypothetical protein 0.0282 0.1792 0.5888
Trypanosoma brucei Voltage-gated Chloride channel Like 3 0.0023 0.009 0.0325
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0049 0.0255 0.0839
Toxoplasma gondii IMP dehydrogenas 0.0395 0.2536 1
Echinococcus granulosus protein farnesyltransferase subunit beta 0.0065 0.0367 0.0649
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0092 0.054 0.0538
Schistosoma mansoni thyroid hormone receptor 0.0083 0.0481 0.0479
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0064 0.0357 0.0632
Echinococcus granulosus glycine receptor subunit alpha 1 0.0048 0.0252 0.0447
Echinococcus multilocularis alpha(13)fucosyltransferase 0.0027 0.0111 0.0196
Schistosoma mansoni hypothetical protein 0.0152 0.094 0.0939
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0014 0.0027 0.0104
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0024 0.0095 0.0348
Trypanosoma brucei protein kinase, putative 0.0026 0.0109 0.0398
Echinococcus granulosus rhodopsin orphan GPCR 0.0472 0.3043 0.539
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0014 0.0028 0.0027
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0019 0.0061 0.0196
Loa Loa (eye worm) AGC/PKA protein kinase 0.0019 0.0061 0.02
Plasmodium falciparum inosine-5'-monophosphate dehydrogenase 0.0371 0.2381 1
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0018 0.0057 0.0183
Echinococcus granulosus Transcription initiation factor TFIID subunit 0.0016 0.0041 0.0073
Brugia malayi bHLH-PAS transcription factor 0.0037 0.0177 0.0576
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0026 0.0109 0.0409
Echinococcus multilocularis protein farnesyltransferase subunit beta 0.0065 0.0367 0.0649
Loa Loa (eye worm) hypothetical protein 0.0472 0.3043 1
Loa Loa (eye worm) hypothetical protein 0.0018 0.0053 0.0173
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0018 0.0057 0.0056
Trichomonas vaginalis ap endonuclease, putative 0.0021 0.0077 0.0388
Loa Loa (eye worm) hypothetical protein 0.0472 0.3043 1
Schistosoma mansoni serine/threonine protein kinase 0.0014 0.0031 0.0029
Brugia malayi nuclear hormone receptor 0.0018 0.0057 0.0183
Onchocerca volvulus 0.0012 0.0015 0.0045
Schistosoma mansoni regulator of G protein signaling 0.0014 0.0028 0.0027
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0472 0.3043 1
Loa Loa (eye worm) hypothetical protein 0.0017 0.0045 0.0148
Brugia malayi nuclear receptor NHR-88 0.0018 0.0057 0.0183
Schistosoma mansoni RAR-like nuclear receptor 0.0018 0.0057 0.0056
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0013 0.0025 0.0044
Echinococcus granulosus inositol monophosphatase 1 0.0046 0.0238 0.0421
Schistosoma mansoni growth hormone secretagogue receptor 0.0472 0.3043 0.3042
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0149 0.0919 0.5108
Loa Loa (eye worm) hypothetical protein 0.0472 0.3043 1
Giardia lamblia Fructose-bisphosphate aldolase 0.0149 0.0919 0.5108
Onchocerca volvulus 0.0472 0.3043 1
Brugia malayi Hemopexin family protein 0.0013 0.0019 0.0058
Leishmania major protein farnesyltransferase alpha subunit, putative 0.0073 0.0417 0.1627
Onchocerca volvulus 0.0013 0.002 0.0062
Echinococcus granulosus alpha 1A adrenergic receptor 0.0472 0.3043 0.539
Echinococcus granulosus histone acetyltransferase MYST2 0.0028 0.0118 0.021
Onchocerca volvulus 0.0472 0.3043 1
Echinococcus granulosus eukaryotic initiation factor 4A 0.011 0.0657 0.1164
Onchocerca volvulus 0.0472 0.3043 1
Mycobacterium leprae Possible regulatory protein 0.0013 0.002 0.0052
Schistosoma mansoni DNA polymerase eta 0.0038 0.0186 0.0184
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.002 0.0069
Loa Loa (eye worm) hypothetical protein 0.0023 0.009 0.0296
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0031 0.0142 0.054
Schistosoma mansoni AMP-activated protein kinase gamma regulatory subunit 0.0023 0.009 0.0089
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0021 0.0077 0.0137
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0015 0.0032 0.0058
Mycobacterium ulcerans hypothetical protein 0.0023 0.009 0.0328
Echinococcus multilocularis G protein coupled receptor 139 0.0472 0.3043 0.539
Schistosoma mansoni hypothetical protein 0.0867 0.5646 0.5646
Loa Loa (eye worm) hypothetical protein 0.0166 0.1028 0.3377
Brugia malayi Sodium:solute symporter family protein 0.0045 0.0235 0.0768
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0095 0.0455
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0021 0.0071 0.0126
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0021 0.0077 0.0254
Echinococcus multilocularis neuropeptide s receptor 0.0472 0.3043 0.539
Brugia malayi hypothetical protein 0.0472 0.3043 1
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0027 0.0104
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0018 0.0057 0.0101
Loa Loa (eye worm) hypothetical protein 0.0045 0.0231 0.076
Toxoplasma gondii aldehyde dehydrogenase 0.0031 0.014 0.0498
Brugia malayi alpha1,3-fucosyltransferase homologue 0.0063 0.0348 0.114
Loa Loa (eye worm) hypothetical protein 0.0472 0.3043 1
Onchocerca volvulus 0.0017 0.0045 0.0143
Brugia malayi Matrix metalloprotease, N-terminal domain containing protein 0.0011 0.0007 0.0019
Brugia malayi hypothetical protein 0.0014 0.0028 0.0087
Echinococcus multilocularis dna polymerase eta 0.0038 0.0186 0.0329
Loa Loa (eye worm) steroid hormone receptor 0.0018 0.0057 0.0187
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0472 0.3043 0.3042
Schistosoma mansoni neuropeptide receptor 0.0472 0.3043 0.3042
Brugia malayi Serotonin receptor 0.0472 0.3043 1
Echinococcus granulosus g-protein coupled receptor 0.0472 0.3043 0.539
Mycobacterium ulcerans DNA polymerase IV 0.0034 0.0161 0.0607
Brugia malayi ancient conserved domain protein 4 0.0023 0.009 0.0292
Onchocerca volvulus 0.0472 0.3043 1
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0031 0.0142 0.0251
Echinococcus multilocularis regulator of G protein signaling 0.0014 0.0028 0.0049
Plasmodium vivax geranylgeranyltransferase, putative 0.0018 0.0053 0.0161
Trichomonas vaginalis CMGC family protein kinase 0.0026 0.0109 0.0564
Leishmania major inosine-5-monophosphate dehydrogenase 0.0395 0.2536 1
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0049 0.0262 0.0859
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0149 0.0919 0.509
Wolbachia endosymbiont of Brugia malayi IMP dehydrogenase 0.0395 0.2536 1
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0019 0.0061 0.0196
Leishmania major peptidyl-prolyl cis-trans isomerase, putative 0.0012 0.0016 0.0041
Brugia malayi Fli-1 protein 0.015 0.0925 0.3035
Giardia lamblia Rab geranylgeranyltransferase 0.0282 0.1792 1
Schistosoma mansoni biogenic amine receptor 0.0472 0.3043 0.3042
Mycobacterium tuberculosis Conserved hypothetical membrane protein 0.0023 0.009 0.0328
Schistosoma mansoni sex comb on midleg homolog 0.0024 0.0096 0.0095
Plasmodium vivax RNA helicase-1, putative 0.011 0.0657 0.2716
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0014 0.0027 0.0104
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0048 0.0252 0.0447
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.0065 0.0367 0.2009
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0472 0.3043 1
Brugia malayi hypothetical protein 0.0472 0.3043 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0472 0.3043 0.539
Mycobacterium tuberculosis Conserved protein 0.0023 0.009 0.0328
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0019 0.0061 0.0108
Mycobacterium tuberculosis Probable inosine-5'-monophosphate dehydrogenase GuaB2 (imp dehydrogenase) (inosinic acid dehydrogenase) (inosinate dehydrogenase 0.0395 0.2536 1
Trichomonas vaginalis AGC family protein kinase 0.0019 0.0061 0.0295
Trypanosoma brucei DNA polymerase IV, putative 0.0031 0.0139 0.0516
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.01 0.0597 0.1057
Echinococcus multilocularis rhodopsin orphan GPCR 0.0472 0.3043 0.539
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0031 0.0142 0.0251
Echinococcus granulosus rhodopsin orphan GPCR 0.0472 0.3043 0.539
Echinococcus granulosus g protein coupled receptor 0.0472 0.3043 0.539
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.0061 0.0059
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0472 0.3043 0.539
Schistosoma mansoni amine GPCR 0.0472 0.3043 0.3042
Loa Loa (eye worm) hypothetical protein 0.0472 0.3043 1
Loa Loa (eye worm) hypothetical protein 0.0038 0.0186 0.0611
Echinococcus multilocularis ankyrin repeat protein 0.0477 0.3081 0.5456
Loa Loa (eye worm) hypothetical protein 0.011 0.0657 0.2159
Echinococcus multilocularis sodium coupled monocarboxylate transporter 1 0.0045 0.0235 0.0416
Loa Loa (eye worm) hypothetical protein 0.0472 0.3043 1
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.0061 0.0059
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0156 0.0966 0.317
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0472 0.3043 0.539
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0472 0.3043 0.539
Schistosoma mansoni regulator of G protein signaling 0.0014 0.0028 0.0027
Giardia lamblia 5-AMP-activated protein kinase, gamma-1 subunit 0.0023 0.009 0.046
Echinococcus multilocularis sodium:glucose cotransporter 2 0.0178 0.1109 0.1964
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0013 0.0023 0.0071
Trypanosoma brucei DNA polymerase IV, putative 0.0034 0.0161 0.0604
Loa Loa (eye worm) hypothetical protein 0.0024 0.0095 0.0313
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0039 0.0192 0.0728
Brugia malayi hypothetical protein 0.0472 0.3043 1
Echinococcus granulosus glycine receptor subunit beta 0.0048 0.0252 0.0447
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0108 0.0645 0.2119
Onchocerca volvulus 0.0042 0.0216 0.0704
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0048 0.0252 0.0829
Trypanosoma cruzi hypothetical protein, conserved 0.0073 0.0417 0.1627
Onchocerca volvulus 0.0045 0.0235 0.0768
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0149 0.0919 0.5108
Echinococcus granulosus tumor protein p63 0.0306 0.1954 0.3461
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.001 0.0001 0.0003
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0472 0.3043 0.3042
Echinococcus multilocularis voltage dependent calcium channel 0.0064 0.0357 0.0632
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0015 0.0037 0.0065
Schistosoma mansoni biogenic amine receptor 0.0472 0.3043 0.3042
Brugia malayi Latrophilin receptor protein 2 0.0015 0.0037 0.0117
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0018 0.0057 0.0187
Toxoplasma gondii LsmAD domain-containing protein 0.003 0.0134 0.0474
Wolbachia endosymbiont of Brugia malayi Mg2+/Co2+ transporter 0.0023 0.009 0.03
Echinococcus multilocularis rhodopsin orphan GPCR 0.0472 0.3043 0.539
Brugia malayi Prenyltransferase and squalene oxidase repeat family protein 0.0018 0.0053 0.0168
Loa Loa (eye worm) neuropeptide F receptor 0.0472 0.3043 1
Echinococcus multilocularis receptor type tyrosine protein phosphatase zeta 0.0124 0.0753 0.1333
Chlamydia trachomatis CBS domain-containing protein 0.0023 0.009 1
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0013 0.0023 0.0071
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0018 0.0057 0.0056
Schistosoma mansoni mixed-lineage leukemia protein mll 0.013 0.079 0.0789
Plasmodium vivax prenyltransferase alpha subunit, putative 0.0282 0.1792 0.751
Brugia malayi RNA binding protein 0.0062 0.0342 0.112
Onchocerca volvulus 0.0472 0.3043 1
Schistosoma mansoni ap endonuclease 0.0021 0.0077 0.0076
Loa Loa (eye worm) hypothetical protein 0.0472 0.3043 1
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0005
Loa Loa (eye worm) hypothetical protein 0.0018 0.0055 0.0181
Schistosoma mansoni single-minded 0.0049 0.0261 0.026
Schistosoma mansoni terminal deoxycytidyl transferase 0.0021 0.0071 0.007
Onchocerca volvulus 0.0073 0.0417 0.1366
Brugia malayi GnHR receptor homolog 0.0472 0.3043 1
Loa Loa (eye worm) hypothetical protein 0.0027 0.0111 0.0364
Schistosoma mansoni hypothetical protein 0.0012 0.0015 0.0014
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0342 0.0341
Echinococcus multilocularis rhodopsin orphan GPCR 0.0472 0.3043 0.539
Loa Loa (eye worm) hypothetical protein 0.0014 0.0028 0.0092
Mycobacterium ulcerans hypothetical protein 0.0024 0.0095 0.0348
Chlamydia trachomatis Mg++ transporter 0.0023 0.009 1
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.0065 0.0367 0.2009
Schistosoma mansoni hypothetical protein 0.0064 0.0359 0.0358
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0019 0.0061 0.0208
Echinococcus granulosus serotonin receptor 0.0472 0.3043 0.539
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0005
Echinococcus multilocularis microtubule associated protein 2 0.0353 0.2258 0.3999
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0013 0.0023 0.0071
Loa Loa (eye worm) hypothetical protein 0.0016 0.0041 0.0136
Loa Loa (eye worm) hypothetical protein 0.0049 0.0255 0.0839
Loa Loa (eye worm) hypothetical protein 0.0472 0.3043 1
Echinococcus granulosus 26S proteasome regulatory subunit N11 0.0014 0.0031 0.0055
Loa Loa (eye worm) 26S proteasome regulatory subunit rpn11 0.0014 0.0031 0.0101
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0012 0.0014 0.0029
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0024 0.0096 0.0312
Mycobacterium tuberculosis Conserved protein 0.0023 0.009 0.0328
Echinococcus multilocularis dnaJ subfamily B 0.0867 0.5646 1
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0092 0.054 0.2104
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0028 0.0118 0.021
Trypanosoma brucei Voltage-gated Chloride channel Like 1 0.0023 0.009 0.0325
Entamoeba histolytica acyl-coA synthetase, putative 0.0024 0.0095 0.0455
Schistosoma mansoni hypothetical protein 0.0025 0.0098 0.0097
Echinococcus granulosus regulator of G protein signaling 7 0.0014 0.0028 0.0049
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0028 0.0111
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0005
Brugia malayi steroid hormone receptor 0.0018 0.0057 0.0183
Trichomonas vaginalis protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative 0.0282 0.1792 1
Schistosoma mansoni axis inhibition protein axin 0.0014 0.0028 0.0027
Trypanosoma cruzi Eukaryotic initiation factor 4A-1 0.011 0.0657 0.2576
Echinococcus granulosus neuropeptide receptor 0.0472 0.3043 0.539
Brugia malayi photoreceptor-specific nuclear receptor 0.0018 0.0057 0.0183
Loa Loa (eye worm) hypothetical protein 0.0024 0.0095 0.0313
Loa Loa (eye worm) hypothetical protein 0.0024 0.0096 0.0316
Giardia lamblia Manganese-dependent inorganic pyrophosphatase, putative 0.0023 0.009 0.046
Toxoplasma gondii hypothetical protein 0.0073 0.0417 0.1597
Trichomonas vaginalis rotamase, putative 0.004 0.0198 0.1067
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0018 0.0057 0.0183
Trypanosoma brucei DNA polymerase kappa, putative 0.0034 0.0161 0.0604
Trichomonas vaginalis protein farnesyltransferase beta subunit, putative 0.0018 0.0053 0.0249
Echinococcus granulosus L aminoadipate semialdehyde 0.0042 0.0216 0.0382
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0472 0.3043 0.539
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0472 0.3043 1
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0472 0.3043 1
Echinococcus granulosus ecdysone induced protein 78C 0.0018 0.0057 0.0101
Schistosoma mansoni voltage-gated cation channel 0.0064 0.0357 0.0356
Echinococcus granulosus dna polymerase kappa 0.0034 0.0161 0.0285
Loa Loa (eye worm) calcium channel 0.0064 0.0357 0.1173
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0012 0.0015 0.0026
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0028 0.0118 0.0385
Schistosoma mansoni high-affinity choline transporter 0.0045 0.0235 0.0234
Brugia malayi GH02984p 0.0045 0.0235 0.0768
Loa Loa (eye worm) hypothetical protein 0.0019 0.006 0.0197
Loa Loa (eye worm) hypothetical protein 0.0472 0.3043 1
Schistosoma mansoni opsin-like receptor 0.0472 0.3043 0.3042
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.001 0.0001 0.0003
Echinococcus granulosus sodium:glucose cotransporter 0.0178 0.1109 0.1964
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0064 0.0357 0.0632
Onchocerca volvulus Matrilysin homolog 0.0057 0.0308 0.1008
Schistosoma mansoni amine GPCR 0.0472 0.3043 0.3042
Schistosoma mansoni survival motor neuron protein 0.0025 0.0098 0.0097
Loa Loa (eye worm) hypothetical protein 0.0472 0.3043 1
Trichomonas vaginalis type I geranylgeranyltransferase beta subunit, putative 0.0065 0.0367 0.2009
Onchocerca volvulus 0.0025 0.0098 0.0318
Loa Loa (eye worm) hypothetical protein 0.0472 0.3043 1
Echinococcus granulosus dro:myosuppressin receptor 0.0472 0.3043 0.539
Trypanosoma brucei DNA polymerase kappa, putative 0.0034 0.0161 0.0604
Echinococcus granulosus mitogen activated protein kinase 0.0026 0.0109 0.0192
Echinococcus granulosus GPCR family 2 0.0015 0.0037 0.0065
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0048 0.0252 0.0447
Schistosoma mansoni glutaminase 0.014 0.0856 0.0854
Echinococcus granulosus neuropeptides capa receptor 0.0472 0.3043 0.539
Echinococcus multilocularis mitogen activated protein kinase 0.0026 0.0109 0.0192
Trichomonas vaginalis geranylgeranyl transferase type beta subunit, putative 0.0065 0.0367 0.2009
Echinococcus granulosus SNF4:AMP activated protein kinase gamma subunit 0.0023 0.009 0.016
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0092 0.054 0.2955
Trypanosoma cruzi hypothetical protein, conserved 0.0073 0.0417 0.1627
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0156 0.0966 0.3174
Loa Loa (eye worm) hypothetical protein 0.0226 0.1426 0.4686
Echinococcus granulosus cpg binding protein 0.0064 0.036 0.0637
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.0065 0.0367 0.2009
Schistosoma mansoni chloride channel protein 0.0023 0.009 0.0089
Loa Loa (eye worm) hypothetical protein 0.0033 0.0154 0.0507
Echinococcus multilocularis sodium:myo inositol cotransporter 0.0178 0.1109 0.1964
Loa Loa (eye worm) inositol-1 0.0046 0.0238 0.0781
Schistosoma mansoni inositol monophosphatase 0.0046 0.0238 0.0236
Echinococcus multilocularis mitogen activated protein kinase 3 0.0026 0.0109 0.0192
Onchocerca volvulus 0.0011 0.0009 0.0024
Entamoeba histolytica deoxycytidyl transferase, putative 0.0021 0.0071 0.032
Echinococcus granulosus transcription factor Dp 1 0.0053 0.0285 0.0505
Trichomonas vaginalis geranylgeranyl transferase type I beta subunit, putative 0.0065 0.0367 0.2009
Loa Loa (eye worm) hypothetical protein 0.0472 0.3043 1
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0472 0.3043 0.539
Trypanosoma cruzi AMP-activated protein kinase, gamma regulatory subunit 0.0023 0.009 0.0335
Loa Loa (eye worm) jmjC domain-containing protein 0.0034 0.0157 0.0514
Echinococcus granulosus H:Cl exchange transporter 7 0.0023 0.009 0.016
Loa Loa (eye worm) fli-1 protein 0.015 0.0925 0.3039
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0013 0.002 0.0069
Brugia malayi hypothetical protein 0.0472 0.3043 1
Echinococcus granulosus GA binding protein alpha chain 0.0049 0.0262 0.0463
Echinococcus granulosus glycine receptor subunit alpha 1 0.0048 0.0252 0.0447
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.001 0.0001 0.0003
Echinococcus granulosus sodium coupled monocarboxylate transporter 1 0.0045 0.0235 0.0416
Leishmania major geranylgeranyltransferase, putative 0.0018 0.0053 0.0187
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0011 0.0011 0.002
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0046 0.0238 0.0912
Loa Loa (eye worm) hypothetical protein 0.0472 0.3043 1
Toxoplasma gondii peptidylprolyl isomerase 0.0039 0.0192 0.0705
Brugia malayi Matrixin family protein 0.0058 0.032 0.1047
Echinococcus multilocularis high affinity choline transporter 1 0.0045 0.0235 0.0416
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0014 0.0027 0.0104
Loa Loa (eye worm) hypothetical protein 0.0023 0.009 0.0296
Echinococcus granulosus voltage dependent calcium channel 0.0024 0.0093 0.0164
Loa Loa (eye worm) hypothetical protein 0.0472 0.3043 1
Loa Loa (eye worm) hypothetical protein 0.0015 0.0037 0.0121
Echinococcus granulosus 5' AMP activated protein kinase subunit gamma 0.0023 0.009 0.016
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.002 0.0069
Brugia malayi Fucosyl transferase family protein 0.0063 0.0348 0.114
Loa Loa (eye worm) hypothetical protein 0.0063 0.0348 0.1144
Trypanosoma cruzi protein farnesyltransferase alpha subunit, putative 0.0073 0.0417 0.1627
Schistosoma mansoni nuclear hormone receptor 0.0018 0.0057 0.0056
Plasmodium falciparum ataxin-2 like protein, putative 0.003 0.0134 0.0505
Toxoplasma gondii exonuclease III APE 0.0021 0.0077 0.0249
Plasmodium falciparum cysteine repeat modular protein 1 0.0012 0.0015 0.0002
Onchocerca volvulus 0.0472 0.3043 1
Trypanosoma brucei GMP reductase 0.0395 0.2536 1
Loa Loa (eye worm) hypothetical protein 0.0226 0.1426 0.4686
Trypanosoma cruzi DNA polymerase kappa, putative 0.0034 0.0161 0.0615
Loa Loa (eye worm) glutaminase 2 0.014 0.0856 0.2812
Loa Loa (eye worm) prenyltransferase alpha subunit repeat containing protein 0.0073 0.0417 0.137
Echinococcus multilocularis Rab geranylgeranyltransferase, beta subunit 0.0018 0.0053 0.0093
Schistosoma mansoni hypothetical protein 0.0018 0.0057 0.0055
Entamoeba histolytica PH domain containing protein kinase, putative 0.0019 0.0061 0.0261
Echinococcus multilocularis 26S proteasome regulatory subunit N11 0.0011 0.0008 0.0014
Toxoplasma gondii CBS domain-containing protein 0.0023 0.009 0.03
Giardia lamblia Manganese-dependent inorganic pyrophosphatase, putative 0.0023 0.009 0.046
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0019 0.0061 0.0108
Brugia malayi mbt repeat family protein 0.0024 0.0096 0.0312
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0014 0.0027 0.0104
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.003 0.0134 0.0237
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0021 0.0077 0.0353
Echinococcus granulosus single minded 2 0.0037 0.0177 0.0313
Plasmodium vivax ataxin-2 like protein, putative 0.003 0.0134 0.0505
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.002 0.0069
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0014 0.0027 0.0104
Brugia malayi Prenyltransferase and squalene oxidase repeat family protein 0.0065 0.0367 0.12
Mycobacterium tuberculosis Probable conserved transmembrane alanine and leucine rich protein 0.0023 0.009 0.0328
Loa Loa (eye worm) hypothetical protein 0.0014 0.0028 0.0092
Trypanosoma brucei DNA polymerase kappa, putative 0.0018 0.0051 0.0171
Echinococcus granulosus alpha13fucosyltransferase 0.0027 0.0111 0.0196
Echinococcus granulosus rhodopsin orphan GPCR 0.0472 0.3043 0.539
Loa Loa (eye worm) hypothetical protein 0.0011 0.0007 0.0024
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0472 0.3043 0.539
Echinococcus granulosus matrix metallopeptidase 7 M10 family 0.0069 0.0391 0.0693
Loa Loa (eye worm) melatonin receptor type 1A 0.0472 0.3043 1
Trichomonas vaginalis adenylate cyclase, putative 0.0013 0.002 0.0069
Loa Loa (eye worm) hypothetical protein 0.0472 0.3043 1
Brugia malayi ancient conserved domain protein 2 0.0023 0.009 0.0292
Loa Loa (eye worm) AGC/PKA protein kinase 0.0019 0.0061 0.02
Brugia malayi PAS domain containing protein 0.0049 0.0261 0.0854
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0064 0.0357 0.0356
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0124 0.0753 0.4153
Echinococcus multilocularis eukaryotic initiation factor 4A III 0.011 0.0657 0.1164
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0019 0.0061 0.0195
Onchocerca volvulus 0.0092 0.0539 0.1766
Loa Loa (eye worm) hypothetical protein 0.0472 0.3043 1
Trypanosoma brucei inosine-5'-monophosphate dehydrogenase 0.0395 0.2536 1
Entamoeba histolytica hypothetical protein 0.0014 0.0028 0.0076
Brugia malayi Immunoglobulin I-set domain containing protein 0.01 0.0596 0.1955
Loa Loa (eye worm) matrixin family protein 0.002 0.0066 0.0216
Wolbachia endosymbiont of Brugia malayi parvulin-like peptidyl-prolyl isomerase, PPID 0.0012 0.0016 0.0005
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0149 0.0919 0.5108
Brugia malayi GMP reductase 0.0164 0.1016 0.3336
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0013 0.002 0.0036
Brugia malayi Voltage gated chloride channel family protein 0.0023 0.009 0.0292
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0024 0.0095 0.0348
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0013 0.002 0.006
Trypanosoma cruzi Protein prenyltransferase alpha subunit repeat, putative 0.0073 0.0417 0.1627
Schistosoma mansoni biogenic amine (5HT) receptor 0.0472 0.3043 0.3042
Onchocerca volvulus 0.0472 0.3043 1
Echinococcus granulosus somatostatin receptor 0.0472 0.3043 0.539
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0046 0.0238 0.0886
Brugia malayi hypothetical protein 0.0472 0.3043 1
Echinococcus granulosus tachykinin peptides receptor 99D 0.0472 0.3043 0.539
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0095 0.0348
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0095 0.0309
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0156 0.0966 0.1711
Schistosoma mansoni hypothetical protein 0.0015 0.0037 0.0035
Echinococcus granulosus FTZ F1 alpha 0.0018 0.0057 0.0101
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0064 0.0357 0.0632
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0013 0.002 0.0036
Loa Loa (eye worm) hypothetical protein 0.0472 0.3043 1
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.001 0.0001 0.0003
Loa Loa (eye worm) TK/KIN16 protein kinase 0.01 0.0596 0.1959
Trypanosoma brucei hypothetical protein, conserved 0.0012 0.0014 0.0025
Loa Loa (eye worm) hypothetical protein 0.0018 0.0057 0.0187
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0064 0.0357 0.1169
Loa Loa (eye worm) MH2 domain-containing protein 0.0116 0.0701 0.2305
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.001 0.0001 0.0003
Trypanosoma cruzi chloride channel protein, putative 0.0023 0.009 0.0335
Loa Loa (eye worm) voltage-dependent calcium channel 0.0024 0.0093 0.0304
Plasmodium falciparum protein MAM3, putative 0.0023 0.009 0.032
Echinococcus granulosus H:Cl exchange transporter 3 0.0023 0.009 0.016
Trypanosoma cruzi DNA polymerase kappa, putative 0.0034 0.0161 0.0615
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0005
Loa Loa (eye worm) hypothetical protein 0.0472 0.3043 1
Schistosoma mansoni coup transcription factor 0.0018 0.0057 0.0056
Giardia lamblia DINP protein human, muc B family 0.0024 0.0093 0.0479
Echinococcus granulosus H:Cl exchange transporter 4 0.0023 0.009 0.016
Brugia malayi A-kinase anchor protein 10, precursor 0.0014 0.0028 0.0087
Toxoplasma gondii PPIC-type PPIASE domain-containing protein 0.0012 0.0016 0.0005
Schistosoma mansoni opsin-like receptor 0.0472 0.3043 0.3042
Loa Loa (eye worm) hypothetical protein 0.0046 0.0237 0.0778
Schistosoma mansoni biogenic amine (5HT) receptor 0.0472 0.3043 0.3042
Brugia malayi CBS domain containing protein 0.0023 0.009 0.0292
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.001 0.0001 0.0005
Leishmania major eukaryotic initiation factor 4a, putative 0.011 0.0657 0.2576
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0472 0.3043 0.3042
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0472 0.3043 0.3042
Echinococcus granulosus tissue type plasminogen activator 0.0012 0.0015 0.0027
Schistosoma mansoni hypothetical protein 0.0211 0.1326 0.1325
Mycobacterium leprae conserved hypothetical protein 0.0012 0.0014 0.0029
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0472 0.3043 0.539
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0015 0.0037 0.0065
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0094 0.0553 0.0551
Loa Loa (eye worm) hypothetical protein 0.0023 0.009 0.0296
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0021 0.0071 0.0126
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0014 0.0028 0.0049
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0018 0.0057 0.0183
Onchocerca volvulus 0.0045 0.0231 0.0755
Echinococcus multilocularis somatostatin receptor 0.0472 0.3043 0.539
Brugia malayi inosine-5'-monophosphate dehydrogenase family protein 0.0395 0.2536 0.8331
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0018 0.0057 0.0101
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0018 0.0057 0.0101
Trypanosoma cruzi geranylgeranyl transferase type II beta subunit, putative 0.0018 0.0053 0.0187
Schistosoma mansoni steroid hormone receptor ad4bp 0.0018 0.0057 0.0056
Schistosoma mansoni lozenge 0.0028 0.0123 0.0121
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0019 0.0061 0.0219
Echinococcus granulosus high affinity choline transporter 1 0.0045 0.0235 0.0416
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0472 0.3043 0.3042
Giardia lamblia Kinase, AGC PKA 0.0019 0.0061 0.0295
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0472 0.3043 0.539
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0018 0.0057 0.0101
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0472 0.3043 0.3042
Brugia malayi hypothetical protein 0.0018 0.0057 0.0182
Echinococcus multilocularis matrix metallopeptidase 7 (M10 family) 0.0069 0.0391 0.0693
Entamoeba histolytica hypothetical protein 0.0018 0.0057 0.0238
Mycobacterium leprae conserved hypothetical protein 0.0023 0.009 0.0328
Brugia malayi larval opioid receptor 0.0472 0.3043 1
Loa Loa (eye worm) hypothetical protein 0.0472 0.3043 1
Toxoplasma gondii AGC kinase 0.0019 0.0061 0.0184
Echinococcus granulosus expressed protein 0.0273 0.1731 0.3066
Echinococcus granulosus geranylgeranyl transferase type I beta subunit 0.0018 0.0053 0.0093
Onchocerca volvulus Matrix metalloproteinase homolog 0.002 0.0066 0.0212
Echinococcus multilocularis tar DNA binding protein 0.0062 0.0342 0.0606
Trypanosoma cruzi hypothetical protein, conserved 0.0018 0.0053 0.0187
Trypanosoma brucei DNA polymerase kappa, putative 0.0034 0.0161 0.0604
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.001 0.0001 0.0003
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0014 0.0027 0.0104
Onchocerca volvulus 0.0472 0.3043 1
Echinococcus granulosus sex peptide receptor 0.0472 0.3043 0.539
Echinococcus multilocularis g-protein coupled receptor 0.0472 0.3043 0.539
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0012 0.0016 0.0041
Echinococcus multilocularis polycomb protein SCMH1 0.0024 0.0096 0.017
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0019 0.0058 0.0102
Trichomonas vaginalis CMGC family protein kinase 0.0026 0.0109 0.0564
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0017 0.0045 0.0044
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0149 0.0919 0.5108
Echinococcus multilocularis g protein coupled receptor 0.0472 0.3043 0.539
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0018 0.0057 0.0183
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0018 0.0057 0.0056
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0019 0.0061 0.0219
Echinococcus multilocularis H(+):Cl() exchange transporter 4 0.0023 0.009 0.016
Toxoplasma gondii proteasome regulatory subunit 0.0014 0.0031 0.0065
Echinococcus multilocularis rhodopsin orphan GPCR 0.0472 0.3043 0.539
Schistosoma mansoni DEAD box ATP-dependent RNA helicase 0.011 0.0657 0.0656
Schistosoma mansoni axis inhibition protein axin 0.0014 0.0028 0.0027
Echinococcus multilocularis lysine specific demethylase 5A 0.003 0.0134 0.0237
Echinococcus granulosus mixed lineage leukemia protein mll 0.0016 0.0039 0.0069
Loa Loa (eye worm) hypothetical protein 0.0472 0.3043 1
Schistosoma mansoni microtubule-associated protein tau 0.0353 0.2258 0.2257
Brugia malayi hypothetical protein 0.0014 0.0028 0.0087
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0013 0.002 0.0067
Brugia malayi inosine-5'-monophosphate dehydrogenase 0.0164 0.1016 0.3336
Trypanosoma brucei geranylgeranyl transferase type II beta subunit, putative 0.0018 0.0053 0.0176
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0064 0.0357 0.0356
Echinococcus granulosus histone lysine methyltransferase setb 0.0017 0.0045 0.008
Brugia malayi hypothetical protein 0.0019 0.0064 0.0205
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0472 0.3043 0.539
Mycobacterium ulcerans inosine 5'-monophosphate dehydrogenase 0.0395 0.2536 1
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0018 0.0057 0.0183
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0027 0.0104
Giardia lamblia Rab geranylgeranyltransferase 0.0018 0.0053 0.0249
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.001 0.0001 0.0005
Echinococcus granulosus glycine receptor subunit beta 0.0048 0.0252 0.0447
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0472 0.3043 0.3042
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0013 0.0025 0.0044
Brugia malayi Ets-domain containing protein 0.0049 0.0262 0.0855
Echinococcus multilocularis neuropeptides capa receptor 0.0472 0.3043 0.539
Onchocerca volvulus 0.0472 0.3043 1
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0012 0.0015 0.0026
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0342 0.0341
Brugia malayi hypothetical protein 0.0472 0.3043 1
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0019 0.0061 0.0208
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0026 0.0109 0.0357
Echinococcus granulosus expressed protein 0.004 0.0198 0.0351
Loa Loa (eye worm) hypothetical protein 0.0472 0.3043 1
Toxoplasma gondii hypothetical protein 0.0019 0.006 0.0181
Loa Loa (eye worm) hypothetical protein 0.0045 0.0232 0.0763
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0018 0.0057 0.0187
Loa Loa (eye worm) hypothetical protein 0.0048 0.0252 0.0829
Echinococcus multilocularis glycine receptor subunit beta 0.0048 0.0252 0.0447
Schistosoma mansoni protein tyrosine phosphatase non-receptor type nt1 0.0156 0.0966 0.0965
Plasmodium falciparum acyl-CoA synthetase 0.0018 0.0055 0.0171
Treponema pallidum exodeoxyribonuclease (exoA) 0.0021 0.0077 0.0694
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0018 0.0057 0.0183
Echinococcus granulosus 7TM GPCR rhodopsin 0.0472 0.3043 0.539
Plasmodium vivax protein prenyltransferase alpha subunit, putative 0.0073 0.0417 0.1701
Brugia malayi Steroid receptor seven-up type 2 0.0018 0.0057 0.0183
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0073 0.0416 0.1618
Echinococcus multilocularis protein farnesyltransferase alpha subunit 0.0282 0.1792 0.3174
Entamoeba histolytica hypothetical protein 0.0014 0.0028 0.0076
Echinococcus multilocularis transfer RNA-Lys 0.0037 0.0177 0.0313
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0005
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0067 0.0234
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0472 0.3043 0.539
Loa Loa (eye worm) hypothetical protein 0.0472 0.3043 1
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0092 0.054 0.177
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0472 0.3043 0.3042
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0027 0.0104
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0095 0.0356
Loa Loa (eye worm) LGC-31 protein 0.001 0.0001 0.0005
Loa Loa (eye worm) hypothetical protein 0.0472 0.3043 1
Trypanosoma cruzi hypothetical protein, conserved 0.0018 0.0053 0.0187
Leishmania major DNA polymerase eta, putative 0.0038 0.0186 0.0714
Echinococcus granulosus glycine receptor subunit alpha 1 0.0048 0.0252 0.0447
Schistosoma mansoni hypothetical protein 0.0472 0.3043 0.3042
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0048 0.0163
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0039 0.0192 0.0739
Mycobacterium leprae PROBABLE INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE GUAB1(IMP DEHYDROGENASE) (IMPDH) (IMPD) 0.0187 0.1171 0.4601
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0282 0.1792 1
Echinococcus multilocularis 26S proteasome regulatory subunit N11 0.0014 0.0031 0.0055
Echinococcus multilocularis orexin receptor type 2 0.0472 0.3043 0.539
Schistosoma mansoni hypothetical protein 0.0033 0.0154 0.0153
Echinococcus granulosus hypothetical protein 0.0472 0.3043 0.539
Schistosoma mansoni alpha(13)fucosyltransferase 0.0063 0.0348 0.0347
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.001 0.0001 0.0005
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0043 0.0222 0.0725
Echinococcus granulosus regulator of G protein signaling 3 0.0014 0.0028 0.0049
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0005
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0026 0.0109 0.0409
Schistosoma mansoni serine/threonine protein kinase 0.0014 0.0031 0.0029
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0018 0.0057 0.0101
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0342 0.0341
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0026 0.0109 0.0409
Echinococcus multilocularis Regulator of G protein signaling 20 0.0014 0.0028 0.0049
Trypanosoma cruzi DNA polymerase eta, putative 0.0038 0.0186 0.0714
Entamoeba histolytica hypothetical protein 0.0018 0.0057 0.0238
Schistosoma mansoni hypothetical protein 0.0472 0.3043 0.3042
Brugia malayi Dopamine receptor 0.0472 0.3043 1
Schistosoma mansoni alpha(13)fucosyltransferase 0.0011 0.0005 0.0004
Loa Loa (eye worm) hypothetical protein 0.0019 0.006 0.0197
Echinococcus granulosus microtubule associated protein 2 0.0353 0.2258 0.3999
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0073 0.0416 0.1618
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0014 0.0027 0.0104
Brugia malayi hypothetical protein 0.0472 0.3043 1
Brugia malayi RNA recognition motif domain containing protein 0.0062 0.0342 0.112
Echinococcus multilocularis eukaryotic initiation factor 4A 0.011 0.0657 0.1164
Trichomonas vaginalis geranylgeranyl transferase type I beta subunit, putative 0.0018 0.0053 0.0249
Schistosoma mansoni neuropeptide receptor 0.0472 0.3043 0.3042
Brugia malayi Kringle domain containing protein 0.0012 0.0015 0.0045
Loa Loa (eye worm) hypothetical protein 0.0472 0.3043 1
Schistosoma mansoni hypothetical protein 0.0472 0.3043 0.3042
Schistosoma mansoni histamine h1 receptor 0.0472 0.3043 0.3042
Echinococcus granulosus regulator of G protein signaling 7 0.0014 0.0028 0.0049
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0472 0.3043 0.3042
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0472 0.3043 0.539
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0021 0.0077 0.0249
Schistosoma mansoni chloride channel protein 0.0023 0.009 0.0089
Echinococcus granulosus axis inhibition protein axin 0.0014 0.0028 0.0049
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0014 0.0031 0.0102
Loa Loa (eye worm) hypothetical protein 0.0472 0.3043 1
Schistosoma mansoni alpha(13)fucosyltransferase 0.0063 0.0348 0.0347
Schistosoma mansoni neuropeptide f receptor 76f 0.0472 0.3043 0.3042
Schistosoma mansoni alpha(13)fucosyltransferase 0.0011 0.0005 0.0004
Schistosoma mansoni alpha(13)fucosyltransferase 0.0011 0.0005 0.0004
Loa Loa (eye worm) chloride channel 3 0.0023 0.009 0.0296
Trypanosoma cruzi proteasome regulatory non-ATPase subunit 11, putative 0.0011 0.0008 0.0011
Echinococcus multilocularis neuropeptide Y receptor 0.0472 0.3043 0.539
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0013 0.002 0.0778
Echinococcus multilocularis regulator of G protein signaling 7 0.0014 0.0028 0.0049
Trypanosoma cruzi lanosterol synthase, putative 0.0018 0.0053 0.0187
Onchocerca volvulus 0.0472 0.3043 1
Echinococcus granulosus neuropeptide receptor A26 0.0472 0.3043 0.539
Toxoplasma gondii hypothetical protein 0.0209 0.1311 0.5142
Leishmania major hypothetical protein, conserved 0.0023 0.009 0.0335
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0048 0.0163
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0017 0.0045 0.0044
Trichomonas vaginalis protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative 0.0209 0.1311 0.7302
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0024 0.0095 0.0348
Brugia malayi hypothetical protein 0.0472 0.3043 1
Echinococcus granulosus neuropeptide Y receptor 0.0472 0.3043 0.539
Echinococcus multilocularis g protein coupled receptor 0.0472 0.3043 0.539
Leishmania major protein kinase A catalytic subunit 0.0019 0.0061 0.0219
Onchocerca volvulus 0.0013 0.0019 0.0058
Brugia malayi G protein-coupled receptor F59B2.13 0.0472 0.3043 1
Brugia malayi Protein prenyltransferase alpha subunit repeat containing protein 0.0073 0.0417 0.1366
Trypanosoma brucei protein farnesyltransferase alpha subunit, putative 0.0073 0.0417 0.1618
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0024 0.0093 0.0349
Onchocerca volvulus 0.0472 0.3043 1
Leishmania major DNA polymerase kappa, putative 0.0024 0.0093 0.0349
Loa Loa (eye worm) hypothetical protein 0.0472 0.3043 1
Loa Loa (eye worm) CXXC zinc finger family protein 0.0061 0.0337 0.1106
Trypanosoma cruzi inosine-5'-monophosphate dehydrogenase, putative 0.0395 0.2536 1
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.001 0.0001 0.0003
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0048 0.0252 0.0447
Brugia malayi Dopamine receptor protein 1 0.0472 0.3043 1
Entamoeba histolytica protein farnesyltransferase beta subunit, putative 0.0065 0.0367 0.1981
Echinococcus granulosus 26S proteasome regulatory subunit N11 0.0011 0.0008 0.0014
Leishmania major hypothetical protein, conserved 0.0012 0.0015 0.0039
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0013 0.002 0.0069
Echinococcus multilocularis protein prenyltransferase alpha subunit 0.0073 0.0417 0.0739
Loa Loa (eye worm) hypothetical protein 0.0064 0.0357 0.1173
Plasmodium falciparum 26S proteasome regulatory subunit RPN11, putative 0.0014 0.0031 0.0069
Trypanosoma cruzi AMP-activated protein kinase, gamma regulatory subunit 0.0023 0.009 0.0335
Leishmania major DNA polymerase eta, putative 0.0024 0.0092 0.0344
Loa Loa (eye worm) TK/ROR protein kinase 0.0014 0.0029 0.0095
Loa Loa (eye worm) hypothetical protein 0.0472 0.3043 1
Mycobacterium tuberculosis Probable cystathionine beta-synthase Cbs (serine sulfhydrase) (beta-thionase) (hemoprotein H-450) 0.0023 0.009 0.0328
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0021 0.0077 0.0388
Loa Loa (eye worm) histone methyltransferase 0.0019 0.0063 0.0209
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0018 0.0057 0.0183
Trypanosoma cruzi protein farnesyltransferase, putative 0.0065 0.0367 0.1428
Trypanosoma cruzi PAB1-binding protein , putative 0.003 0.0134 0.0509
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0472 0.3043 1
Echinococcus multilocularis 5' AMP activated protein kinase subunit gamma 0.0023 0.009 0.016
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0018 0.0057 0.0183
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0012 0.0016 0.0041
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.011 0.0657 0.3638
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0472 0.3043 0.539
Entamoeba histolytica geranylgeranyl transferase beta subunit 0.0018 0.0053 0.0215
Schistosoma mansoni adenoreceptor 0.0472 0.3043 0.3042
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0024 0.0092 0.0309
Brugia malayi neuropeptide F receptor 0.0472 0.3043 1
Schistosoma mansoni protein kinase subunit gamma 0.0023 0.009 0.0089
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0472 0.3043 0.3042
Loa Loa (eye worm) runx1 0.0028 0.0123 0.0403
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0005
Brugia malayi mbt repeat family protein 0.0024 0.0096 0.0312
Loa Loa (eye worm) hypothetical protein 0.0014 0.0028 0.0092
Giardia lamblia Rab geranylgeranyltransferase 0.0073 0.0417 0.2292
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.011 0.0657 0.3638
Onchocerca volvulus 0.0024 0.0096 0.0312
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0198 0.1067
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0043 0.0217 0.0384
Echinococcus granulosus glycoprotein 3 alpha L fucosyltransferase 0.0027 0.0111 0.0196
Mycobacterium tuberculosis Conserved protein 0.0023 0.009 0.0328
Echinococcus multilocularis expressed protein 0.004 0.0198 0.0351
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0472 0.3043 0.3042
Onchocerca volvulus 0.0472 0.3043 1
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.001 0.0001 0.0003
Loa Loa (eye worm) hypothetical protein 0.0042 0.0214 0.0704
Loa Loa (eye worm) prenyltransferase and squalene oxidase repeat family protein 0.0065 0.0367 0.1204
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0067 0.0234
Trypanosoma brucei protein farnesyltransferase beta subunit 0.0065 0.0367 0.1418
Brugia malayi Regulator of G protein signaling domain containing protein 0.0014 0.0028 0.0087
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0342 0.0341
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0019 0.0061 0.0219
Brugia malayi hypothetical protein 0.0166 0.1028 0.3373
Entamoeba histolytica DEAD/DEAH box helicase, putative 0.011 0.0657 0.3616
Echinococcus granulosus 7tm_1 domain containing protein 0.0472 0.3043 0.539
Onchocerca volvulus 0.0472 0.3043 1
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0342 0.0341
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0019 0.0061 0.0108
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0005
Loa Loa (eye worm) RNA binding protein 0.0062 0.0342 0.1124
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0018 0.0057 0.0056
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0472 0.3043 1
Echinococcus multilocularis axis inhibition protein axin 0.0014 0.0028 0.0049
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0021 0.0071 0.0234
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0064 0.0357 0.0632
Mycobacterium tuberculosis Conserved hypothetical membrane protein 0.0023 0.009 0.0328
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0018 0.0057 0.0183
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0472 0.3043 0.3042
Onchocerca volvulus Tyrosine kinase homolog 0.0094 0.0553 0.1812
Echinococcus granulosus endonuclease exonuclease phosphatase 0.01 0.0597 0.1057
Echinococcus multilocularis fmrfamide receptor 0.0472 0.3043 0.539
Echinococcus multilocularis survival motor neuron protein 1 0.0121 0.0732 0.1296
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0472 0.3043 0.539
Mycobacterium ulcerans inosine 5-monophosphate dehydrogenase 0.0187 0.1171 0.4601
Brugia malayi putative neuropeptide receptor NPR1 0.0472 0.3043 1
Echinococcus granulosus neuropeptide Y receptor 0.0472 0.3043 0.539
Loa Loa (eye worm) neuropeptide F receptor 0.0472 0.3043 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.0061 0.02
Loa Loa (eye worm) transcription factor SMAD2 0.0116 0.0701 0.2305
Entamoeba histolytica hypothetical protein 0.0018 0.0057 0.0238
Loa Loa (eye worm) hypothetical protein 0.0472 0.3043 1
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0018 0.0057 0.0056
Schistosoma mansoni alpha(13)fucosyltransferase 0.0011 0.0005 0.0004
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0018 0.0057 0.0101
Brugia malayi G-protein coupled receptor 0.0472 0.3043 1
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0026 0.0109 0.0409
Schistosoma mansoni amine GPCR 0.0472 0.3043 0.3042
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0027 0.0104
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0026 0.0109 0.0398
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0095 0.0309
Echinococcus granulosus tm gpcr rhodopsin 0.0472 0.3043 0.539
Toxoplasma gondii Rab geranylgeranyl transferase type II beta subunit, putative 0.0018 0.0053 0.0151
Schistosoma mansoni hypothetical protein 0.0013 0.0019 0.0017
Loa Loa (eye worm) ACC-1 protein 0.001 0.0001 0.0005
Toxoplasma gondii AGC kinase 0.0019 0.0061 0.0184
Loa Loa (eye worm) hypothetical protein 0.0018 0.0057 0.0187
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.0061 0.0059
Schistosoma mansoni ap endonuclease 0.0021 0.0077 0.0076
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0024 0.0095 0.0348
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0005
Brugia malayi hypothetical protein 0.0045 0.0232 0.0759
Brugia malayi MH2 domain containing protein 0.0116 0.0701 0.2301
Loa Loa (eye worm) hypothetical protein 0.003 0.0134 0.044
Trypanosoma brucei DNA polymerase kappa, putative 0.0034 0.0161 0.0604
Brugia malayi regulator of G-protein signaling egl-10 0.0014 0.0028 0.0087
Loa Loa (eye worm) hypothetical protein 0.0018 0.0055 0.0181
Echinococcus multilocularis regulator of G protein signaling 3 0.0014 0.0028 0.0049
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0472 0.3043 0.3042
Wolbachia endosymbiont of Brugia malayi hemolysin 0.0023 0.009 0.03
Schistosoma mansoni alpha(13)fucosyltransferase 0.0011 0.0005 0.0004
Echinococcus multilocularis histone acetyltransferase MYST2 0.0028 0.0118 0.021
Brugia malayi Cation transporter family protein 0.0048 0.0252 0.0824
Onchocerca volvulus Eukaryotic initiation factor 4A homolog 0.011 0.0657 0.2156
Echinococcus multilocularis fmrfamide receptor 0.0472 0.3043 0.539
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0021 0.0077 0.0285
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.011 0.0657 0.3638
Schistosoma mansoni receptor protein tyrosine phosphatase 0.0124 0.0753 0.0751
Brugia malayi jmjC domain containing protein 0.003 0.0134 0.0435
Treponema pallidum ATP-dependent RNA helicase 0.011 0.0657 0.7103
Brugia malayi eukaryotic initiation factor 4A 0.011 0.0657 0.2156
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0282 0.1792 1
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0034 0.0161 0.0856
Loa Loa (eye worm) hypothetical protein 0.0018 0.0055 0.0181
Trypanosoma cruzi chloride channel protein, putative 0.0023 0.009 0.0335

Activities

Activity type Activity value Assay description Source Reference
CCIC50 (functional) = 18 uM Cytotoxicity against MT-4 cells using a cytopathicity assay. ChEMBL. No reference
CCIC50 (functional) = 18 uM Cytotoxicity against MT-4 cells using a cytopathicity assay. ChEMBL. No reference
EC50 (functional) > 10 uM Anti-HIV activity against MT-4 cells using a cytopathicity assay ChEMBL. No reference
IC50 (binding) = 22 nM Inhibitory activity against purified HIV protease ChEMBL. No reference
IC50 (binding) = 22 nM Inhibitory activity against purified HIV protease ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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