Detailed information for compound 1574853

Basic information

Technical information
  • TDR Targets ID: 1574853
  • Name: (4S)-N-[3-(3-methoxyphenyl)prop-2-ynoxy]-1-az abicyclo[2.2.1]heptan-3-imine
  • MW: 270.326 | Formula: C16H18N2O2
  • H donors: 0 H acceptors: 0 LogP: 2.42 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1cccc(c1)C#CCO/N=C/1\CN2C[C@@H]1CC2
  • InChi: 1S/C16H18N2O2/c1-19-15-6-2-4-13(10-15)5-3-9-20-17-16-12-18-8-7-14(16)11-18/h2,4,6,10,14H,7-9,11-12H2,1H3/b17-16+/t14-/m0/s1
  • InChiKey: FXBXWJPMXQHOGD-VUAZUDAXSA-N  


Substructure search Similarity search

Network

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Synonyms

  • (Z)-[(4S)-1-azabicyclo[2.2.1]heptan-3-ylidene]-[3-(3-methoxyphenyl)prop-2-ynoxy]amine

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0171 0.0142 0.3144
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0019 0.0006 0.0908
Mycobacterium tuberculosis Possible haloalkane dehalogenase DhaA (1-chlorohexane halidohydrolase) 0.0027 0.0013 0.0007
Trichomonas vaginalis ap endonuclease, putative 0.0061 0.0043 0.1006
Echinococcus multilocularis snurportin 1 0.031 0.0267 0.0267
Treponema pallidum phosphoglycolate phosphatase 0.0026 0.0011 0.1124
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0009 0.0198
Trypanosoma cruzi heat shock protein 85, putative 0.0025 0.0011 0.0926
Trichomonas vaginalis 2-deoxyglucose-6-phosphate phosphatase, putative 0.0026 0.0011 0.0267
Trichomonas vaginalis antibiotic synthetase, putative 0.0023 0.0009 0.0211
Loa Loa (eye worm) hypothetical protein 0.0022 0.0008 0.0168
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.0007 0.0626
Leishmania major DNA polymerase eta, putative 0.0141 0.0115 0.9647
Echinococcus granulosus GPCR family 2 0.0083 0.0063 0.0063
Entamoeba histolytica hypothetical protein 0.0117 0.0094 0.0962
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0033 0.0018 0.0085
Brugia malayi Patched family protein 0.002 0.0006 0.0133
Mycobacterium ulcerans exodeoxyribonuclease V (alpha chain), RecD 0.0611 0.0538 0.0535
Echinococcus multilocularis G-protein coupled receptor, putative 0.0033 0.0018 0.0018
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0022 0.0008 0.0008
Mycobacterium tuberculosis Probable hydrolase 0.0146 0.012 0.0114
Schistosoma mansoni hypothetical protein 0.003 0.0015 0.0073
Loa Loa (eye worm) patched family protein 0.002 0.0006 0.0133
Brugia malayi hypothetical protein 0.0033 0.0018 0.04
Mycobacterium ulcerans hypothetical protein 0.0038 0.0023 0.002
Echinococcus multilocularis jumonji domain containing protein 0.0042 0.0026 0.0026
Loa Loa (eye worm) hypothetical protein 0.0021 0.0007 0.0163
Trichomonas vaginalis 2-deoxyglucose-6-phosphate phosphatase, putative 0.0026 0.0011 0.0267
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0011 0.0267
Mycobacterium tuberculosis Possible ATP-dependent DNA helicase 0.0077 0.0057 0.0051
Schistosoma mansoni hypothetical protein 0.0083 0.0063 0.0298
Onchocerca volvulus Huntingtin homolog 0.0128 0.0104 0.2433
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0022 0.0008 0.0168
Brugia malayi nuclear receptor NHR-88 0.0022 0.0008 0.0168
Trichomonas vaginalis D-aminoacylase, putative 0.0146 0.012 0.2809
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0035 0.002 0.002
Giardia lamblia Phosphoglycolate phosphatase 0.0026 0.0011 0.0058
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.0015 0.1293
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0003 0.0064
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0022 0.0008 0.0168
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0023 0.0009 0.0003
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0033 0.0018 0.0018
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.0021 0.0007 0.0163
Onchocerca volvulus 0.0033 0.0018 0.0425
Trypanosoma brucei heat shock protein, putative 0.0032 0.0017 0.1414
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0022 0.0008 0.0168
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0035 0.002 0.1636
Trypanosoma brucei ISWI complex protein 0.0015 0.0002 0.0137
Echinococcus multilocularis ubiquitin conjugating enzyme E2 N 0.0083 0.0063 0.0063
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0133
Trichomonas vaginalis 2-deoxyglucose-6-phosphate phosphatase, putative 0.0026 0.0011 0.0267
Loa Loa (eye worm) hypothetical protein 0.0059 0.0041 0.0906
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0033 0.0018 0.0085
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0022 0.0008 0.0036
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0133
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0035 0.002 0.1636
Brugia malayi Patched family protein 0.002 0.0006 0.0133
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.0083 0.0063 0.5279
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0079 0.0059 0.0183
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0019 0.0006 0.0479
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0099 0.0077 0.0077
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0035 0.002 0.0013
Loa Loa (eye worm) hypothetical protein 0.0021 0.0007 0.0163
Trichomonas vaginalis 2-deoxyglucose-6-phosphate phosphatase, putative 0.0026 0.0011 0.0267
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0083 0.0063 0.1483
Trichomonas vaginalis 2-deoxyglucose-6-phosphate phosphatase, putative 0.0026 0.0011 0.0267
Trypanosoma cruzi hypothetical protein, conserved 0.0021 0.0007 0.0616
Echinococcus multilocularis Niemann Pick C1 protein 0.0326 0.0281 0.0281
Loa Loa (eye worm) hypothetical protein 0.0517 0.0453 1
Loa Loa (eye worm) hypothetical protein 0.003 0.0015 0.0342
Echinococcus granulosus alpha 1A adrenergic receptor 0.0033 0.0018 0.0018
Echinococcus multilocularis thymidine phosphorylase 1.1143 1 1
Echinococcus multilocularis conserved hypothetical protein 0.0038 0.0023 0.0023
Echinococcus multilocularis haloacid dehalogenase hydrolase 0.0026 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0022 0.0008 0.0168
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0061 0.0043 0.3582
Mycobacterium leprae Probable lipase LipE 0.0146 0.012 0.04
Echinococcus granulosus neuropeptide receptor 0.0033 0.0018 0.0018
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0007 0.0173
Brugia malayi Calcitonin receptor-like protein seb-1 0.0264 0.0225 0.4979
Trypanosoma brucei DNA polymerase kappa, putative 0.0098 0.0076 0.6348
Trichomonas vaginalis ran, putative 0.0021 0.0007 0.0176
Loa Loa (eye worm) hypothetical protein 0.0033 0.0018 0.04
Mycobacterium ulcerans hypothetical protein 0.0027 0.0013 0.001
Mycobacterium ulcerans hydrolase 0.0027 0.0013 0.001
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0023 0.0009 0.0006
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0934 0.0827 0.0822
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0061 0.0043 0.0043
Brugia malayi Patched family protein 0.002 0.0006 0.0133
Loa Loa (eye worm) hypothetical protein 0.0033 0.0018 0.04
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.003 0.0015 0.0073
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0023 0.0009 0.0009
Trypanosoma brucei chrX additional, unordered contigs 0.0044 0.0028 0.2317
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0035 0.002 0.3099
Schistosoma mansoni zinc finger protein 0.0015 0.0002 0.0008
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0022 0.0008 0.0168
Entamoeba histolytica haloacid dehalogenase-like hydrolase domain-containing protein 0.0026 0.0011 0.0117
Trypanosoma brucei hypothetical protein, conserved 0.0044 0.0028 0.2317
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0003 0.0015
Echinococcus granulosus importin subunit beta 1 0.0029 0.0014 0.0014
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0046 0.0215
Brugia malayi HAD-superfamily hydrolase, subfamily IA, variant 1 containing protein 0.0026 0.0011 0.0251
Trichomonas vaginalis 2-deoxyglucose-6-phosphate phosphatase, putative 0.0026 0.0011 0.0267
Schistosoma mansoni jumonji/arid domain-containing protein 0.004 0.0024 0.0114
Loa Loa (eye worm) hypothetical protein 0.0043 0.0027 0.0597
Loa Loa (eye worm) hypothetical protein 0.0033 0.0018 0.04
Echinococcus granulosus bloom syndrome protein 0.0019 0.0006 0.0006
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0033 0.0018 0.0085
Trypanosoma cruzi hydrolase-like protein 0.0027 0.0013 0.1067
Trichomonas vaginalis conserved hypothetical protein 0.014 0.0114 0.2678
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0019 0.0006 0.0908
Trypanosoma brucei hypothetical protein, conserved 0.0026 0.0011 0.095
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0035 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0146 0.012 0.2642
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0022 0.0008 0.0036
Mycobacterium ulcerans lipase LipD 0.0146 0.012 0.0117
Schistosoma mansoni topbp1 0.0021 0.0007 0.0035
Onchocerca volvulus 0.0146 0.012 0.2809
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0033 0.0018 0.0018
Mycobacterium leprae Probable homoserine o-acetyltransferase MetA 0.0027 0.0013 0.0019
Echinococcus granulosus neuropeptide Y receptor 0.0033 0.0018 0.0018
Plasmodium vivax hypothetical protein, conserved 0.0027 0.0013 0.1067
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0022 0.0008 0.0036
Leishmania major acetyl-CoA synthetase, putative 0.0023 0.0009 0.0751
Brugia malayi MH2 domain containing protein 0.0122 0.0098 0.2156
Brugia malayi jmjC domain containing protein 0.004 0.0024 0.0537
Plasmodium falciparum epoxide hydrolase 1 0.0027 0.0013 0.2022
Schistosoma mansoni endoplasmin 0.0032 0.0017 0.008
Trichomonas vaginalis 2-deoxyglucose-6-phosphate phosphatase, putative 0.0026 0.0011 0.0267
Trypanosoma brucei DNA polymerase kappa, putative 0.0141 0.0115 0.9647
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.006 0.0042 0.0042
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0078 0.0059 0.0276
Mycobacterium ulcerans proline iminopeptidase PIP 0.0027 0.0013 0.001
Brugia malayi Dopamine receptor 0.0033 0.0018 0.04
Plasmodium vivax patched family protein, putative 0.002 0.0006 0.0504
Entamoeba histolytica DNA repair and recombination protein RAD52, putative 0.1095 0.0973 1
Mycobacterium leprae conserved hypothetical protein 0.0146 0.012 0.04
Trypanosoma cruzi DNA polymerase eta, putative 0.0141 0.0115 0.9647
Schistosoma mansoni adenoreceptor 0.0033 0.0018 0.0085
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 0.0083 0.0063 0.1395
Echinococcus granulosus serotonin receptor 0.0033 0.0018 0.0018
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0055 0.0037 0.0825
Schistosoma mansoni hypothetical protein 0.0135 0.0109 0.0515
Echinococcus granulosus abhydrolase domain containing protein 11 0.0027 0.0013 0.0013
Mycobacterium ulcerans hydrolase 0.0026 0.0011 0.0009
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0235 0.02 0.02
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0055 0.0037 0.0176
Toxoplasma gondii propionate-CoA ligase 0.0023 0.0009 0.0751
Brugia malayi CHE-14 protein 0.014 0.0114 0.2519
Schistosoma mansoni amine GPCR 0.0033 0.0018 0.0085
Leishmania major heat shock protein 83-1 0.0032 0.0017 0.1414
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0022 0.0008 0.0168
Onchocerca volvulus 0.0033 0.0018 0.0425
Schistosoma mansoni hypothetical protein 0.018 0.015 0.0707
Onchocerca volvulus 0.002 0.0006 0.0142
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0022 0.0008 0.0008
Brugia malayi protein C24B5.3 0.002 0.0006 0.0133
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0035 0.002 0.002
Brugia malayi TAR-binding protein 0.0064 0.0046 0.1009
Loa Loa (eye worm) hypothetical protein 0.0033 0.0018 0.04
Echinococcus granulosus neuropeptide s receptor 0.0485 0.0424 0.0424
Echinococcus multilocularis dro:myosuppressin receptor 0.0033 0.0018 0.0018
Plasmodium falciparum replication factor C subunit 1, putative 0.0021 0.0007 0.1168
Brugia malayi hypothetical protein 0.002 0.0006 0.0133
Onchocerca volvulus 0.0033 0.0018 0.0425
Echinococcus multilocularis bloom syndrome protein 0.0019 0.0006 0.0006
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0009 0.0006
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0133
Mycobacterium tuberculosis Conserved protein 0.0146 0.012 0.0114
Schistosoma mansoni neuropeptide receptor 0.0033 0.0018 0.0085
Mycobacterium ulcerans lignin peroxidase LipJ 0.0027 0.0013 0.001
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0133
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0019 0.0006 0.0006
Loa Loa (eye worm) RNA binding protein 0.0064 0.0046 0.1009
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0033 0.0018 0.0085
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0027 0.0013 0.03
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0035 0.002 0.002
Giardia lamblia ENC6 protein 0.0027 0.0013 0.0073
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0133
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0023 0.0009 0.0751
Trypanosoma cruzi heat shock protein 90, putative 0.0019 0.0005 0.0432
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0023 0.0009 0.0003
Loa Loa (eye worm) transcription factor SMAD2 0.0122 0.0098 0.2156
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0023 0.0009 0.0006
Brugia malayi hypothetical protein 0.002 0.0006 0.0133
Schistosoma mansoni endoplasmin 0.0032 0.0017 0.008
Echinococcus granulosus heat shock protein 0.0032 0.0017 0.0017
Plasmodium vivax ataxin-2 like protein, putative 0.0078 0.0058 0.4883
Echinococcus multilocularis geminin 0.238 0.2127 0.2127
Onchocerca volvulus 0.0146 0.012 0.2809
Brugia malayi Patched family protein 0.002 0.0006 0.0133
Trichomonas vaginalis 2-deoxyglucose-6-phosphate phosphatase, putative 0.0026 0.0011 0.0267
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0009 0.0198
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0023 0.0009 0.0006
Treponema pallidum rep helicase, single-stranded DNA-dependent ATPase (rep) 0.0038 0.0023 0.4346
Mycobacterium ulcerans heat shock protein 90 0.0025 0.0011 0.0008
Mycobacterium tuberculosis Conserved hypothetical protein 0.0141 0.0115 0.0109
Trypanosoma brucei hydrolase, alpha/beta fold family, putative 0.0027 0.0013 0.1067
Brugia malayi hypothetical protein 0.0033 0.0018 0.04
Echinococcus granulosus rhodopsin orphan GPCR 0.0033 0.0018 0.0018
Brugia malayi isocitrate dehydrogenase 0.0035 0.002 0.0432
Mycobacterium ulcerans bromoperoxidase BpoC 0.0027 0.0013 0.001
Loa Loa (eye worm) beta-lactamase 0.0146 0.012 0.2642
Loa Loa (eye worm) hypothetical protein 0.0416 0.0362 0.7997
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0027 0.0013 0.03
Loa Loa (eye worm) hypothetical protein 0.0023 0.0009 0.0198
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0079 0.0059 0.0056
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0025 0.0011 0.1046
Echinococcus multilocularis tar DNA binding protein 0.0064 0.0046 0.0046
Schistosoma mansoni cpg binding protein 0.0032 0.0017 0.0079
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0023 0.0009 0.0006
Echinococcus granulosus Protein patched homolog 1 0.014 0.0114 0.0114
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0022 0.0008 0.0168
Loa Loa (eye worm) hypothetical protein 0.0021 0.0007 0.0163
Toxoplasma gondii HEAT repeat-containing protein 0.0029 0.0014 0.1203
Plasmodium vivax heat shock protein 86, putative 0.0032 0.0017 0.1414
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0022 0.0008 0.0168
Loa Loa (eye worm) hypothetical protein 0.0033 0.0018 0.04
Brugia malayi latrophilin 2 splice variant baaae 0.018 0.015 0.3322
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0022 0.0008 0.0008
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0033 0.0018 0.0018
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0416 0.0362 0.7997
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0141 0.0115 0.9647
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0033 0.0018 0.0085
Toxoplasma gondii patched family protein 0.002 0.0006 0.0504
Brugia malayi haloacid dehalogenase-like hydrolase family protein 0.0026 0.0011 0.0251
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0009 0.0006
Loa Loa (eye worm) hypothetical protein 0.004 0.0024 0.0528
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0141 0.0115 0.0115
Trichomonas vaginalis 2-deoxyglucose-6-phosphate phosphatase, putative 0.0026 0.0011 0.0267
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0011 0.0267
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0055 0.0037 0.0825
Leishmania major DNA damage repair protein, putative 0.0044 0.0028 0.2317
Echinococcus granulosus FTZ F1 alpha 0.0022 0.0008 0.0008
Echinococcus granulosus heat shock protein 90 0.0025 0.0011 0.0011
Leishmania major hydrolase-like protein 0.0027 0.0013 0.1067
Trypanosoma cruzi hypothetical protein, conserved 0.0027 0.0013 0.1067
Onchocerca volvulus 0.0033 0.0018 0.0425
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0033 0.0018 0.0018
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0007 0.0626
Loa Loa (eye worm) hypothetical protein 0.0146 0.012 0.2642
Mycobacterium ulcerans hypothetical protein 0.0027 0.0013 0.001
Mycobacterium tuberculosis Possible haloalkane dehalogenase 0.0027 0.0013 0.0007
Giardia lamblia Hydrolase, haloacid dehalogenase-like family 0.0026 0.0011 0.0058
Echinococcus granulosus histone lysine methyltransferase setb 0.0078 0.0059 0.0059
Loa Loa (eye worm) patched family protein 0.002 0.0006 0.0133
Echinococcus granulosus g protein coupled receptor 0.0033 0.0018 0.0018
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0061 0.0043 0.3582
Brugia malayi Ubiquitin conjugating enzyme protein 13 0.0083 0.0063 0.1395
Loa Loa (eye worm) ab-hydrolase associated lipase region family protein 0.0027 0.0013 0.0282
Trypanosoma cruzi hypothetical protein, conserved 0.0146 0.012 1
Onchocerca volvulus Bile acid receptor homolog 0.0022 0.0008 0.0179
Loa Loa (eye worm) hypothetical protein 0.014 0.0114 0.2519
Trypanosoma brucei DNA polymerase kappa, putative 0.0141 0.0115 0.9647
Plasmodium vivax endoplasmin, putative 0.0032 0.0017 0.1414
Echinococcus granulosus lysosomal acid lipase:cholesteryl ester 0.0027 0.0013 0.0013
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0007 0.0173
Mycobacterium leprae POSSIBLE EPOXIDE HYDROLASE EPHE (EPOXIDE HYDRATASE) (ARENE-OXIDE HYDRATASE) 0.0027 0.0013 0.0019
Loa Loa (eye worm) TAR-binding protein 0.0064 0.0046 0.1009
Leishmania major 4-coumarate:coa ligase-like protein 0.0079 0.0059 0.4919
Trypanosoma brucei heat shock protein, putative 0.0032 0.0017 0.1414
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0033 0.0018 0.0018
Schistosoma mansoni myosin xvIII 0.0033 0.0018 0.0085
Schistosoma mansoni choline dehydrogenase 0.0026 0.0011 0.0053
Schistosoma mansoni heat shock protein 0.0032 0.0017 0.008
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0046 0.0215
Brugia malayi photoreceptor-specific nuclear receptor 0.0022 0.0008 0.0168
Trypanosoma cruzi DNA polymerase kappa, putative 0.0141 0.0115 0.9647
Mycobacterium tuberculosis Protein tyrosine kinase transcriptional regulatory protein PtkA 0.0026 0.0011 0.0005
Treponema pallidum phosphoglycolate phosphatase 0.0026 0.0011 0.1124
Loa Loa (eye worm) melatonin receptor type 1A 0.0033 0.0018 0.04
Schistosoma mansoni ap endonuclease 0.0061 0.0043 0.0201
Brugia malayi Patched related family protein 12 0.002 0.0006 0.0133
Echinococcus multilocularis neuropeptide receptor 0.0033 0.0018 0.0018
Onchocerca volvulus 0.002 0.0006 0.0142
Mycobacterium ulcerans hypothetical protein 0.0079 0.0059 0.0056
Mycobacterium leprae Probable exported protease 0.0027 0.0013 0.0019
Mycobacterium ulcerans peroxidase BpoB 0.0027 0.0013 0.001
Entamoeba histolytica HAD hydrolase, family IA, variant 3 0.0026 0.0011 0.0117
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0021 0.0007 0.0173
Brugia malayi alpha/beta hydrolase 0.0027 0.0013 0.0282
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0133
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0141 0.0115 0.271
Brugia malayi hypothetical protein 0.0078 0.0058 0.129
Brugia malayi larval opioid receptor 0.0033 0.0018 0.04
Echinococcus granulosus nibrin 0.0021 0.0007 0.0007
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0023 0.0009 0.1422
Trypanosoma brucei DNA polymerase kappa, putative 0.0141 0.0115 0.9647
Loa Loa (eye worm) hypothetical protein 0.0033 0.0018 0.04
Entamoeba histolytica acyl-CoA synthetase, putative 0.0079 0.0059 0.0605
Trypanosoma cruzi PAB1-binding protein , putative 0.0078 0.0058 0.4883
Echinococcus granulosus cpg binding protein 0.0032 0.0017 0.0017
Loa Loa (eye worm) isocitrate dehydrogenase 0.0035 0.002 0.0432
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0022 0.0008 0.0008
Mycobacterium tuberculosis Conserved protein 0.0027 0.0013 0.0007
Entamoeba histolytica HAD hydrolase, family IA, variant 3 0.0026 0.0011 0.0117
Onchocerca volvulus Epoxide hydrolase 1 homolog 0.0027 0.0013 0.03
Echinococcus multilocularis somatostatin receptor 0.0033 0.0018 0.0018
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0033 0.0018 0.04
Brugia malayi steroid hormone receptor 0.0022 0.0008 0.0168
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.031 0.0267 0.5903
Brugia malayi RNA, U transporter 1 0.0083 0.0063 0.1382
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0133
Plasmodium vivax ATP-dependent DNA helicase UvrD, putative 0.0038 0.0023 0.1905
Leishmania major heat shock protein 83-1 0.0032 0.0017 0.1414
Onchocerca volvulus 0.0033 0.0018 0.0425
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0023 0.0009 0.0751
Echinococcus multilocularis endoplasmin 0.0025 0.0011 0.0011
Mycobacterium ulcerans hypothetical protein 0.0027 0.0013 0.001
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0017 0.0003 0.0003
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0022 0.0008 0.0168
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0023 0.0009 0.0006
Toxoplasma gondii hypothetical protein 0.002 0.0006 0.0504
Brugia malayi hypothetical protein 0.005 0.0034 0.0741
Schistosoma mansoni nuclear hormone receptor 0.0022 0.0008 0.0036
Schistosoma mansoni alpha-1 adrenergic receptor 0.0033 0.0018 0.0085
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0033 0.0018 0.0085
Echinococcus granulosus tm gpcr rhodopsin 0.0033 0.0018 0.0018
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0011 0.0267
Schistosoma mansoni cellular tumor antigen P53 0.0109 0.0086 0.0404
Schistosoma mansoni RAR-like nuclear receptor 0.0022 0.0008 0.0036
Brugia malayi jmjC domain containing protein 0.0099 0.0077 0.1709
Echinococcus multilocularis lysosomal acid lipase:cholesteryl ester 0.0027 0.0013 0.0013
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0035 0.002 0.1636
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0033 0.0018 0.0018
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0117 0.0094 0.0094
Schistosoma mansoni hypothetical protein 0.0105 0.0083 0.039
Trichomonas vaginalis 2-deoxyglucose-6-phosphate phosphatase, putative 0.0026 0.0011 0.0267
Mycobacterium ulcerans acyl-CoA synthetase 0.0079 0.0059 0.0056
Schistosoma mansoni hypothetical protein 0.002 0.0006 0.003
Schistosoma mansoni hypothetical protein 0.0404 0.0351 0.1651
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0146 0.012 0.2642
Brugia malayi putative neuropeptide receptor NPR1 0.0033 0.0018 0.04
Onchocerca volvulus 0.0033 0.0018 0.0425
Brugia malayi follicle stimulating hormone receptor 0.0033 0.0018 0.04
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.006 0.0042 0.0042
Toxoplasma gondii alpha/beta hydrolase, putative 0.0027 0.0013 0.1067
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0007 0.0165
Brugia malayi Patched family protein 0.002 0.0006 0.0133
Brugia malayi Niemann-Pick C1 protein precursor 0.0326 0.0281 0.6215
Brugia malayi hypothetical protein 0.002 0.0006 0.0133
Echinococcus granulosus snurportin 1 0.031 0.0267 0.0267
Plasmodium falciparum phd finger protein, putative 0.003 0.0015 0.2449
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0059 0.0041 0.0296
Loa Loa (eye worm) hypothetical protein 0.0033 0.0018 0.04
Trypanosoma brucei hypothetical protein, conserved 0.0146 0.012 1
Plasmodium falciparum heat shock protein 90 0.0032 0.0017 0.2679
Onchocerca volvulus 0.0033 0.0018 0.0425
Leishmania major hypothetical protein, conserved 0.0078 0.0058 0.4883
Schistosoma mansoni opsin-like receptor 0.0033 0.0018 0.0085
Chlamydia trachomatis exodeoxyribonuclease V subunit alpha 0.0611 0.0538 0.4665
Entamoeba histolytica HAD hydrolase, family IA, variant 3 0.0026 0.0011 0.0117
Brugia malayi Bromodomain containing protein 0.0033 0.0018 0.0387
Schistosoma mansoni hypothetical protein 0.238 0.2127 1
Schistosoma mansoni hypothetical protein 0.0033 0.0018 0.0085
Echinococcus granulosus dro:myosuppressin receptor 0.0033 0.0018 0.0018
Onchocerca volvulus 0.0028 0.0014 0.0323
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0024 0.0009 0.0044
Echinococcus granulosus G protein coupled receptor 139 0.0033 0.0018 0.0018
Echinococcus granulosus hypothetical protein 0.0033 0.0018 0.0018
Echinococcus granulosus tumor protein p63 0.0742 0.0655 0.0655
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0022 0.0008 0.0168
Echinococcus multilocularis g-protein coupled receptor 0.0033 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0146 0.012 0.2642
Brugia malayi hypothetical protein 0.0033 0.0018 0.04
Brugia malayi exodeoxyribonuclease III family protein 0.0061 0.0043 0.0947
Schistosoma mansoni hypothetical protein 0.0015 0.0002 0.0008
Mycobacterium ulcerans short chain dehydrogenase 0.0027 0.0013 0.001
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0061 0.0043 0.044
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0033 0.0018 0.0085
Mycobacterium ulcerans epoxide hydrolase EphF 0.0027 0.0013 0.001
Onchocerca volvulus 0.0033 0.0018 0.0425
Trypanosoma cruzi pantothenate kinase subunit, putative 0.0015 0.0002 0.018
Schistosoma mansoni cpg binding protein 0.0032 0.0017 0.0079
Echinococcus granulosus Niemann Pick C1 protein 0.0466 0.0407 0.0407
Plasmodium falciparum ataxin-2 like protein, putative 0.0078 0.0058 0.9249
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0133
Echinococcus multilocularis abhydrolase domain containing protein 3 0.0027 0.0013 0.0013
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0059 0.0041 0.0035
Brugia malayi hypothetical protein 0.0021 0.0007 0.0163
Mycobacterium ulcerans anthranilate phosphoribosyltransferase 0.3145 0.2814 0.2812
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0033 0.0018 0.04
Brugia malayi beta-lactamase family protein 0.0146 0.012 0.2642
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.0007 0.1186
Leishmania major GTP-binding protein, putative 0.0021 0.0007 0.0626
Mycobacterium tuberculosis Possible short-chain dehydrogenase EphD 0.0027 0.0013 0.0007
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0033 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0133
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0021 0.0007 0.0173
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0059 0.0041 0.0038
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0033 0.0018 0.0018
Schistosoma mansoni biogenic amine receptor 0.0033 0.0018 0.0085
Echinococcus multilocularis protein dispatched 1 0.016 0.0132 0.0132
Echinococcus granulosus neuropeptides capa receptor 0.0033 0.0018 0.0018
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0062 0.0044 0.0206
Echinococcus multilocularis rhodopsin orphan GPCR 0.0033 0.0018 0.0018
Brugia malayi ecdysteroid receptor 0.0022 0.0008 0.0168
Mycobacterium tuberculosis Probable ATP-dependent DNA helicase II UvrD2 0.0038 0.0023 0.0017
Mycobacterium ulcerans exodeoxyribonuclease V (gamma chain), RecC 0.1286 0.1144 0.1141
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0033 0.0018 0.0018
Trypanosoma brucei DNA polymerase kappa, putative 0.0141 0.0115 0.9647
Schistosoma mansoni heat shock protein 0.0032 0.0017 0.008
Schistosoma mansoni ran 0.0021 0.0007 0.0035
Entamoeba histolytica HAD hydrolase, family IA, variant 3 0.0026 0.0011 0.0117
Echinococcus multilocularis rhodopsin orphan GPCR 0.0033 0.0018 0.0018
Leishmania major hypothetical protein, conserved 0.0027 0.0013 0.1067
Brugia malayi putative neuropeptide receptor 0.0033 0.0018 0.04
Entamoeba histolytica acyl-CoA synthetase, putative 0.0079 0.0059 0.0605
Schistosoma mansoni hypothetical protein 0.238 0.2127 1
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0061 0.0043 0.6786
Plasmodium vivax hypothetical protein, conserved 0.0027 0.0013 0.1067
Mycobacterium ulcerans 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase BphD 0.0027 0.0013 0.001
Onchocerca volvulus 0.0033 0.0018 0.0425
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0033 0.0018 0.0085
Loa Loa (eye worm) hypothetical protein 0.0033 0.0018 0.04
Trichomonas vaginalis 2-deoxyglucose-6-phosphate phosphatase, putative 0.0026 0.0011 0.0267
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0083 0.0063 0.0063
Giardia lamblia Heat shock protein HSP 90-alpha 0.0032 0.0017 0.0116
Loa Loa (eye worm) hypothetical protein 0.0079 0.0059 0.13
Trypanosoma brucei DNA polymerase kappa, putative 0.0098 0.0076 0.6348
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0033 0.0018 0.04
Echinococcus granulosus expressed conserved protein 0.0306 0.0263 0.0263
Leishmania major heat shock protein 83-1 0.0032 0.0017 0.1414
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0033 0.0018 0.04
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0033 0.0018 0.04
Loa Loa (eye worm) hypothetical protein 0.0021 0.0007 0.0163
Plasmodium falciparum acid cluster protein 33 homologue, putative 0.0027 0.0013 0.2022
Mycobacterium tuberculosis Probable epoxide hydrolase EphA (epoxide hydratase) (arene-oxide hydratase) 0.0993 0.0881 0.0875
Leishmania major heat shock protein 83-1 0.0032 0.0017 0.1414
Trypanosoma brucei DNA polymerase kappa, putative 0.0098 0.0076 0.6348
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0033 0.0018 0.0018
Plasmodium vivax alpha/beta hydrolase, putative 0.0027 0.0013 0.1067
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0022 0.0008 0.0036
Trichomonas vaginalis ATP-dependent DNA helicase rep, putative 0.0038 0.0023 0.0535
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0099 0.0077 0.0077
Brugia malayi hypothetical protein 0.0517 0.0453 1
Trypanosoma cruzi ISWI complex protein 0.0015 0.0002 0.0137
Echinococcus multilocularis serotonin receptor 0.0033 0.0018 0.0018
Echinococcus multilocularis replication factor c subunit 1 0.0021 0.0007 0.0007
Mycobacterium tuberculosis Probable exonuclease V (gamma chain) RecC (exodeoxyribonuclease V gamma chain)(exodeoxyribonuclease V polypeptide) 0.1286 0.1144 0.1138
Plasmodium falciparum ubiquitin-conjugating enzyme E2 N, putative 0.0083 0.0063 1
Echinococcus granulosus PHD finger protein rhinoceros 0.003 0.0015 0.0015
Mycobacterium tuberculosis Probable carboxylesterase CaeA 0.0027 0.0013 0.0007
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0055 0.0037 0.0037
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0025 0.0011 0.0013
Loa Loa (eye worm) hypothetical protein 0.0069 0.005 0.1107
Trichomonas vaginalis 2-deoxyglucose-6-phosphate phosphatase, putative 0.0026 0.0011 0.0267
Onchocerca volvulus 0.0023 0.0009 0.0211
Loa Loa (eye worm) RecQ helicase 0.0019 0.0006 0.0127
Leishmania major heat shock protein 83-1 0.0032 0.0017 0.1414
Echinococcus multilocularis haloacid dehalogenase hydrolase 0.0026 0.0011 0.0011
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0146 0.012 0.0117
Brugia malayi neuropeptide F receptor 0.0033 0.0018 0.04
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0023 0.0009 0.0006
Onchocerca volvulus 0.0026 0.0011 0.0267
Loa Loa (eye worm) hypothetical protein 0.0033 0.0018 0.04
Brugia malayi F/Y-rich N-terminus family protein 0.0023 0.0009 0.0191
Chlamydia trachomatis DNA helicase 0.0038 0.0023 0.0136
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0055 0.0037 0.0037
Plasmodium vivax SET domain protein, putative 0.0062 0.0044 0.3668
Echinococcus granulosus orexin receptor type 2 0.0033 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0033 0.0018 0.04
Loa Loa (eye worm) hypothetical protein 0.0033 0.0018 0.04
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0264 0.0225 0.4979
Echinococcus multilocularis Niemann Pick C1 protein 0.0466 0.0407 0.0407
Loa Loa (eye worm) hypothetical protein 0.0033 0.0018 0.04
Onchocerca volvulus 0.0033 0.0018 0.0425
Trichomonas vaginalis 2-deoxyglucose-6-phosphate phosphatase, putative 0.0026 0.0011 0.0267
Brugia malayi hypothetical protein 0.002 0.0006 0.0133
Echinococcus granulosus g protein coupled receptor 0.0033 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0133
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0023 0.0009 0.0751
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0133
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0033 0.0018 0.04
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0019 0.0006 0.0006
Echinococcus multilocularis neuropeptides capa receptor 0.0033 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0326 0.0281 0.6215
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0033 0.0018 0.0018
Mycobacterium tuberculosis Probable lipase LipE 0.0146 0.012 0.0114
Echinococcus granulosus geminin 0.238 0.2127 0.2127
Trichomonas vaginalis 2-deoxyglucose-6-phosphate phosphatase, putative 0.0026 0.0011 0.0267
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0061 0.0043 0.0037
Loa Loa (eye worm) hypothetical protein 0.0033 0.0018 0.04
Schistosoma mansoni hypothetical protein 0.031 0.0267 0.1256
Brugia malayi hypothetical protein 0.0033 0.0018 0.04
Brugia malayi Nuclear hormone receptor-like 1 0.0022 0.0008 0.0168
Loa Loa (eye worm) latrophilin receptor protein 2 0.0083 0.0063 0.1398
Trypanosoma cruzi DNA polymerase eta, putative 0.0044 0.0028 0.2317
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0061 0.0043 0.3582
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0019 0.0006 0.0127
Onchocerca volvulus 0.0105 0.0083 0.1949
Trichomonas vaginalis heat shock protein, putative 0.002 0.0006 0.0137
Brugia malayi hypothetical protein 0.0033 0.0018 0.04
Echinococcus granulosus haloacid dehalogenase hydrolase 0.0026 0.0011 0.0011
Loa Loa (eye worm) HAD-superfamily hydrolase 0.0026 0.0011 0.0251
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0033 0.0018 0.0018
Trichomonas vaginalis DNA helicase recq, putative 0.0019 0.0006 0.0135
Echinococcus multilocularis cpg binding protein 0.0032 0.0017 0.0017
Mycobacterium leprae conserved hypothetical protein 0.0038 0.0023 0.0055
Trypanosoma brucei PAB1-binding protein , putative 0.0078 0.0058 0.4883
Loa Loa (eye worm) hypothetical protein 0.0022 0.0008 0.0168
Mycobacterium ulcerans ATP-dependent DNA helicase II UvrD1 0.0038 0.0023 0.002
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0035 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0022 0.0008 0.0168
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.0007 0.0626
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0078 0.0059 0.0059
Treponema pallidum exodeoxyribonuclease (exoA) 0.0061 0.0043 1
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0009 0.0006
Trichomonas vaginalis DNA polymerase eta, putative 0.0141 0.0115 0.271
Echinococcus granulosus 7tm_1 domain containing protein 0.0033 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0133
Schistosoma mansoni amine GPCR 0.0033 0.0018 0.0085
Plasmodium vivax haloacid dehalogenase-like hydrolase, putative 0.0026 0.0011 0.095
Trichomonas vaginalis antibiotic synthetase, putative 0.0023 0.0009 0.0211
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0023 0.0009 0.0006
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0023 0.0009 0.0751
Leishmania major hydrolase-like protein,esterase-like protein 0.0027 0.0013 0.1067
Mycobacterium ulcerans acyl-CoA synthetase 0.0079 0.0059 0.0056
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0033 0.0018 0.0018
Leishmania major heat shock protein 83-1 0.0032 0.0017 0.1414
Plasmodium falciparum endoplasmin, putative 0.002 0.0006 0.0924
Plasmodium vivax acetyl-CoA synthetase, putative 0.0023 0.0009 0.0751
Mycobacterium ulcerans hypothetical protein 0.0146 0.012 0.0117
Echinococcus granulosus tm gpcr rhodopsin 0.0033 0.0018 0.0018
Brugia malayi Patched family protein 0.002 0.0006 0.0133
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0033 0.0018 0.0425
Brugia malayi Patched family protein 0.002 0.0006 0.0133
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0009 0.0198
Giardia lamblia Grp94/Hsp90 0.0025 0.0011 0.0055
Brugia malayi Pre-SET motif family protein 0.0062 0.0044 0.0969
Schistosoma mansoni hypothetical protein 0.0033 0.0018 0.0085
Loa Loa (eye worm) hypothetical protein 0.0033 0.0018 0.04
Brugia malayi CXXC zinc finger family protein 0.0028 0.0014 0.0303
Brugia malayi Dopamine receptor protein 2 0.0033 0.0018 0.04
Trichomonas vaginalis heat shock protein, putative 0.0025 0.0011 0.026
Leishmania major 4-coumarate:coa ligase-like protein 0.0079 0.0059 0.4919
Leishmania major hydrolase-like protein,esterase-like protein 0.0027 0.0013 0.1067
Brugia malayi Hypothetical 54.7 kDa protein F37A4.1 in chromosome III 0.0027 0.0013 0.0282
Echinococcus granulosus rhodopsin orphan GPCR 0.0033 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0033 0.0018 0.04
Trichomonas vaginalis 2-deoxyglucose-6-phosphate phosphatase, putative 0.0026 0.0011 0.0267
Onchocerca volvulus 0.0033 0.0018 0.0425
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0014 0.1203
Plasmodium falciparum acyl-CoA synthetase 0.0059 0.0041 0.6492
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0133
Trypanosoma brucei heat shock protein 90, putative 0.0032 0.0017 0.1414
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0022 0.0008 0.0008
Schistosoma mansoni amine GPCR 0.0033 0.0018 0.0085
Trypanosoma cruzi heat shock protein 85, putative 0.0032 0.0017 0.1414
Echinococcus granulosus neuropeptide receptor A26 0.0485 0.0424 0.0424
Schistosoma mansoni growth hormone secretagogue receptor 0.0033 0.0018 0.0085
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0133
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0035 0.002 0.002
Echinococcus granulosus abhydrolase domain containing protein 3 0.0027 0.0013 0.0013
Plasmodium falciparum alpha/beta hydrolase, putative 0.0027 0.0013 0.2022
Mycobacterium ulcerans ATP-dependent DNA helicase 0.0077 0.0057 0.0055
Plasmodium falciparum haloacid dehalogenase-like hydrolase, putative 0.0026 0.0011 0.1799
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0023 0.0009 0.0003
Echinococcus granulosus g-protein coupled receptor 0.0033 0.0018 0.0018
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0021 0.0007 0.0173
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0033 0.0018 0.0018
Echinococcus granulosus zinc finger protein 0.0021 0.0007 0.0007
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0055 0.0037 0.0037
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0022 0.0008 0.0168
Leishmania major heat shock protein 83-1 0.0032 0.0017 0.1414
Onchocerca volvulus Alhambra homolog 0.003 0.0015 0.0363
Leishmania major acetyl-CoA synthetase, putative 0.0023 0.0009 0.0751
Toxoplasma gondii heat shock protein HSP90 0.0032 0.0017 0.1414
Loa Loa (eye worm) hypothetical protein 0.0146 0.012 0.2642
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0033 0.0018 0.04
Loa Loa (eye worm) hypothetical protein 0.0033 0.0018 0.04
Toxoplasma gondii homoserine O-acetyltransferase, putative 0.0027 0.0013 0.1067
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.0007 0.0007
Treponema pallidum hypothetical protein 0.0038 0.0023 0.4351
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0033 0.0018 0.0085
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0235 0.02 0.02
Loa Loa (eye worm) hypothetical protein 0.0033 0.0018 0.04
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0055 0.0037 0.0037
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0019 0.0006 0.0006
Toxoplasma gondii heat shock protein 90, putative 0.0032 0.0017 0.1414
Schistosoma mansoni biogenic amine receptor 0.0033 0.0018 0.0085
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0033 0.0018 0.0085
Schistosoma mansoni jumonji/arid domain-containing protein 0.004 0.0024 0.0114
Plasmodium falciparum lipid/sterol:H+ symporter 0.002 0.0006 0.0955
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0326 0.0281 0.2892
Mycobacterium tuberculosis Conserved protein 0.0146 0.012 0.0114
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0428 0.0373 0.8234
Trypanosoma brucei heat shock protein, putative 0.0032 0.0017 0.1414
Trypanosoma cruzi hydrolase, alpha/beta fold family, putative 0.0027 0.0013 0.1067
Brugia malayi AMP-binding enzyme family protein 0.0079 0.0059 0.13
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0062 0.0044 0.0044
Echinococcus multilocularis rhodopsin orphan GPCR 0.0033 0.0018 0.0018
Onchocerca volvulus 0.0023 0.0009 0.0211
Loa Loa (eye worm) hypothetical protein 0.0023 0.0009 0.0198
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0133
Loa Loa (eye worm) G-protein coupled receptor 0.0033 0.0018 0.04
Loa Loa (eye worm) hypothetical protein 0.0021 0.0007 0.0163
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0025 0.0011 0.0005
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0133
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0133
Onchocerca volvulus Protein ultraspiracle homolog 0.0022 0.0008 0.0179
Loa Loa (eye worm) hypothetical protein 0.0033 0.0018 0.04
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0035 0.002 0.1636
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0019 0.0006 0.0479
Schistosoma mansoni steroid hormone receptor ad4bp 0.0022 0.0008 0.0036
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0133
Trichomonas vaginalis heat shock protein, putative 0.0025 0.0011 0.026
Mycobacterium ulcerans exodeoxyribonuclease V (beta chain), RecB 0.0372 0.0323 0.032
Onchocerca volvulus 0.0033 0.0018 0.0425
Schistosoma mansoni hypothetical protein 0.0117 0.0094 0.044
Brugia malayi Patched family protein 0.002 0.0006 0.0133
Toxoplasma gondii isocitrate dehydrogenase 0.0035 0.002 0.1636
Loa Loa (eye worm) hypothetical protein 0.0109 0.0086 0.1897
Mycobacterium ulcerans lipase/esterase 0.0027 0.0013 0.001
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0023 0.0009 0.0198
Brugia malayi beta-lactamase 0.0146 0.012 0.2642
Trypanosoma brucei DNA polymerase kappa, putative 0.0141 0.0115 0.9647
Entamoeba histolytica ubiquitin-conjugating enzyme family protein 0.0083 0.0063 0.0649
Echinococcus granulosus biogenic amine 5HT receptor 0.0033 0.0018 0.0018
Trypanosoma cruzi hypothetical protein, conserved 0.0027 0.0013 0.1067
Schistosoma mansoni transcription factor LCR-F1 0.0117 0.0094 0.044
Loa Loa (eye worm) hypothetical protein 0.0083 0.0063 0.1398
Loa Loa (eye worm) neuropeptide F receptor 0.0033 0.0018 0.04
Schistosoma mansoni hypothetical protein 0.0135 0.0109 0.0515
Mycobacterium tuberculosis Possible phosphatase 0.0026 0.0011 0.0005
Toxoplasma gondii ATPase, AAA family protein 0.0021 0.0007 0.0616
Entamoeba histolytica hypothetical protein 0.0021 0.0007 0.0076
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0033 0.0018 0.0018
Giardia lamblia PHD finger protein 15 0.003 0.0015 0.0101
Schistosoma mansoni DNA polymerase eta 0.0141 0.0115 0.0542
Echinococcus granulosus methyl CpG binding domain protein 2 0.0017 0.0003 0.0003
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.0083 0.0063 0.5279
Onchocerca volvulus Huntingtin homolog 0.0128 0.0104 0.2433
Loa Loa (eye worm) hypothetical protein 0.0033 0.0018 0.04
Entamoeba histolytica Ran family GTPase 0.0021 0.0007 0.0077
Trypanosoma cruzi hypothetical protein, conserved 0.0044 0.0028 0.2317
Trichomonas vaginalis 2-deoxyglucose-6-phosphate phosphatase, putative 0.0026 0.0011 0.0267
Loa Loa (eye worm) hypothetical protein 0.0033 0.0018 0.04
Trypanosoma cruzi hypothetical protein, conserved 0.0044 0.0028 0.2317
Entamoeba histolytica hypothetical protein 0.0312 0.0268 0.2759
Entamoeba histolytica alpha/beta hydrolase domain protein, putative 0.0027 0.0013 0.0131
Loa Loa (eye worm) hypothetical protein 0.0033 0.0018 0.04
Trypanosoma brucei heat shock protein, putative 0.0032 0.0017 0.1414
Schistosoma mansoni thyroid hormone receptor 0.0022 0.0008 0.0036
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0022 0.0008 0.0168
Mycobacterium ulcerans ATP-dependent DNA helicase 0.0077 0.0057 0.0055
Trypanosoma brucei DNA polymerase kappa, putative 0.0141 0.0115 0.9647
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0022 0.0008 0.0168
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0023 0.0009 0.0006
Echinococcus granulosus rhodopsin orphan GPCR 0.0033 0.0018 0.0018
Brugia malayi Alpha/beta hydrolase 0.0027 0.0013 0.0282
Echinococcus multilocularis sterol regulatory element binding protein 0.014 0.0114 0.0114
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0023 0.0009 0.0751
Onchocerca volvulus 0.0033 0.0018 0.0425
Plasmodium vivax importin-beta 2, putative 0.0029 0.0014 0.1203
Leishmania major ATP-dependent DNA helicase, putative 0.0016 0.0003 0.0228
Loa Loa (eye worm) hypothetical protein 0.0141 0.0115 0.2549
Brugia malayi protein C24B5.3 0.002 0.0006 0.0133
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0062 0.0044 0.0206
Plasmodium vivax acyl-CoA synthetase, putative 0.0059 0.0041 0.3427
Brugia malayi DKFZp564C0469 protein 0.0021 0.0007 0.0163
Onchocerca volvulus 0.0021 0.0007 0.0173
Trypanosoma brucei unspecified product 0.0098 0.0076 0.6348
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0055 0.0038 0.0032
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0023 0.0009 0.0006
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0331 0.0286 0.1344
Echinococcus granulosus dnaJ subfamily B 0.0404 0.0351 0.0351
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0009 0.0222
Trypanosoma brucei heat shock protein, putative 0.0032 0.0017 0.1414
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0023 0.0009 0.0751
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0033 0.0018 0.0085
Brugia malayi Bromodomain containing protein 0.0075 0.0055 0.1222
Trypanosoma cruzi FHA domain containing protein, putative 0.0021 0.0007 0.0616
Schistosoma mansoni retinoic acid receptor RXR 0.0022 0.0008 0.0036
Loa Loa (eye worm) hypothetical protein 0.0033 0.0018 0.04
Brugia malayi neuropeptide F receptor 0.0033 0.0018 0.04
Toxoplasma gondii isocitrate dehydrogenase 0.0035 0.002 0.1636
Echinococcus multilocularis rhodopsin orphan GPCR 0.0033 0.0018 0.0018
Entamoeba histolytica acyl-coA synthetase, putative 0.0079 0.0059 0.0605
Onchocerca volvulus 0.0079 0.0059 0.1382
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0061 0.0043 0.0947
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0027 0.0013 0.03
Schistosoma mansoni histamine h1 receptor 0.0033 0.0018 0.0085
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0033 0.0018 0.0085
Onchocerca volvulus 0.0023 0.0009 0.0211
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0022 0.0008 0.0168
Echinococcus granulosus peregrin 0.0033 0.0018 0.0018
Entamoeba histolytica haloacid dehalogenase-like hydrolase domain-containing protein 0.0026 0.0011 0.0117
Loa Loa (eye worm) hypothetical protein 0.0022 0.0008 0.0168
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0022 0.0008 0.0168
Mycobacterium ulcerans non-heme haloperoxidase Hpx 0.0027 0.0013 0.001
Trypanosoma cruzi hypothetical protein, conserved 0.0021 0.0007 0.0616
Loa Loa (eye worm) haloacid dehalogenase-like hydrolase 0.0026 0.0011 0.0251
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0033 0.0018 0.0085
Loa Loa (eye worm) hypothetical protein 0.0033 0.0018 0.04
Echinococcus multilocularis sex peptide receptor 0.0033 0.0018 0.0018
Leishmania major serine peptidase, putative,serine peptidase, Clan SC, Family S9D 0.0027 0.0013 0.1067
Mycobacterium tuberculosis Probable exonuclease V (alpha chain) RecD (exodeoxyribonuclease V alpha chain) (exodeoxyribonuclease V polypeptide) 0.0611 0.0538 0.0532
Loa Loa (eye worm) jmjC domain-containing protein 0.0063 0.0044 0.0981
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0083 0.0063 0.1483
Brugia malayi UPF0017 protein CG3488 0.0027 0.0013 0.0282
Loa Loa (eye worm) patched family protein 0.002 0.0006 0.0133
Mycobacterium ulcerans epoxide hydrolase EphB 0.0027 0.0013 0.001
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0009 0.0006
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0022 0.0008 0.0168
Loa Loa (eye worm) patched family protein 0.002 0.0006 0.0133
Mycobacterium leprae conserved hypothetical protein 0.0103 0.0081 0.0261
Mycobacterium ulcerans hydrolase 0.0027 0.0013 0.001
Schistosoma mansoni coup transcription factor 0.0022 0.0008 0.0036
Mycobacterium ulcerans hypothetical protein 0.0064 0.0046 0.0043
Brugia malayi hypothetical protein 0.0033 0.0018 0.04
Wolbachia endosymbiont of Brugia malayi RecB exonuclease 0.0038 0.0023 0.4351
Loa Loa (eye worm) hypothetical protein 0.0033 0.0018 0.04
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0046 0.0215
Trichomonas vaginalis ap endonuclease, putative 0.0061 0.0043 0.1006
Echinococcus granulosus biogenic amine 5HT receptor 0.0033 0.0018 0.0018
Plasmodium falciparum DNA repair protein REV1, putative 0.0044 0.0028 0.4389
Schistosoma mansoni hypothetical protein 0.0033 0.0018 0.0085
Giardia lamblia Phosphoglycolate phosphatase 0.0026 0.0011 0.0058
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0141 0.0115 0.0115
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0019 0.0006 0.0127
Brugia malayi sulfakinin receptor protein 0.0033 0.0018 0.04
Mycobacterium tuberculosis Probable hydrolase 0.0026 0.0011 0.0005
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0146 0.012 0.0114
Onchocerca volvulus 0.0062 0.0044 0.1031
Plasmodium vivax hypothetical protein, conserved 0.0146 0.012 1
Entamoeba histolytica HAD hydrolase, family IA, variant 3 0.0026 0.0011 0.0117
Brugia malayi beta-lactamase family protein 0.0146 0.012 0.2642
Trichomonas vaginalis 2-deoxyglucose-6-phosphate phosphatase, putative 0.0026 0.0011 0.0267
Loa Loa (eye worm) hypothetical protein 0.0026 0.0011 0.0251
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0146 0.012 0.0114
Onchocerca volvulus Neuropeptide F receptor homolog 0.0033 0.0018 0.0425
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0079 0.0059 0.0056
Trypanosoma brucei hypothetical protein, conserved 0.0044 0.0028 0.2317
Echinococcus granulosus dna polymerase kappa 0.0141 0.0115 0.0115
Mycobacterium ulcerans esterase/lipase LipP 0.0146 0.012 0.0117
Echinococcus multilocularis nibrin 0.0021 0.0007 0.0007
Mycobacterium ulcerans beta-lactamase 0.0146 0.012 0.0117
Trichomonas vaginalis valacyclovir hydrolase, putative 0.0027 0.0013 0.03
Schistosoma mansoni jumonji domain containing protein 0.0079 0.0059 0.0278
Leishmania major heat shock protein 83-1 0.0032 0.0017 0.1414
Treponema pallidum hypothetical protein 0.0038 0.0023 0.4351
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0023 0.0009 0.0198
Schistosoma mansoni cpg binding protein 0.0028 0.0014 0.0065
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0019 0.0006 0.0479
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0033 0.0018 0.0085
Echinococcus multilocularis neuropeptide receptor 0.0033 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0022 0.0008 0.0168
Echinococcus granulosus abhydrolase domain containing protein 0.0027 0.0013 0.0013
Schistosoma mansoni biogenic amine (5HT) receptor 0.0033 0.0018 0.0085
Echinococcus granulosus g protein coupled receptor 0.0033 0.0018 0.0018
Trypanosoma brucei DNA polymerase kappa, putative 0.0141 0.0115 0.9647
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0062 0.0044 0.0208
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0022 0.0008 0.0168
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0009 0.0198
Toxoplasma gondii patched family protein 0.002 0.0006 0.0504
Echinococcus multilocularis lysine specific demethylase 5A 0.0037 0.0021 0.0021
Toxoplasma gondii patched family protein 0.002 0.0006 0.0504
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0022 0.0008 0.0036
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0146 0.012 0.2642
Echinococcus multilocularis rhodopsin orphan GPCR 0.0033 0.0018 0.0018
Giardia lamblia RNA helicase, putative 0.0064 0.0046 0.0417
Loa Loa (eye worm) heat shock protein 90 0.0032 0.0017 0.0374
Mycobacterium leprae Probable hydrolase 0.0026 0.0011 0.0014
Mycobacterium tuberculosis Conserved hypothetical protein 0.0038 0.0023 0.0017
Trichomonas vaginalis penicillin-binding protein, putative 0.0146 0.012 0.2809
Brugia malayi PHD-finger family protein 0.0026 0.0011 0.0254
Echinococcus multilocularis beta LACTamase domain containing family member 0.0146 0.012 0.012
Loa Loa (eye worm) hypothetical protein 0.0033 0.0018 0.04
Brugia malayi hypothetical protein 0.0117 0.0094 0.2068
Trypanosoma cruzi ATP-dependent DNA helicase, putative 0.0038 0.0023 0.1905
Schistosoma mansoni terminal deoxycytidyl transferase 0.0141 0.0115 0.0542
Trypanosoma cruzi heat shock protein 90, putative 0.0025 0.0011 0.0926
Echinococcus multilocularis PHD finger protein rhinoceros 0.003 0.0015 0.0015
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0011 0.0267
Leishmania major heat shock protein 83-1 0.0032 0.0017 0.1414
Brugia malayi ubiquitin conjugating enzyme protein 13 0.0083 0.0063 0.1395
Mycobacterium ulcerans NAD-dependent DNA ligase LigA 0.0021 0.0007 0.0005
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0022 0.0008 0.0008
Onchocerca volvulus 0.0033 0.0018 0.0425
Trypanosoma brucei heat shock protein 90, putative 0.0032 0.0017 0.1414
Leishmania major hypothetical protein, conserved 0.0027 0.0013 0.1067
Brugia malayi RNA recognition motif domain containing protein 0.0064 0.0046 0.1009
Echinococcus granulosus haloacid dehalogenase hydrolase 0.0026 0.0011 0.0011
Mycobacterium ulcerans haloalkane dehalogenase 0.0027 0.0013 0.001
Trypanosoma brucei unspecified product 0.0098 0.0076 0.6348
Giardia lamblia DNA damage repair protein 0.0044 0.0028 0.0227
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0021 0.0007 0.0173
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0023 0.0009 0.0003
Trypanosoma brucei DNA polymerase IV, putative 0.0141 0.0115 0.9647
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0025 0.0011 0.0926
Leishmania major DNA polymerase eta, putative 0.0044 0.0028 0.2317
Mycobacterium leprae Probable exported protease 0.0027 0.0013 0.0019
Mycobacterium leprae Probable anthranilate phosphoribosyltransferase TrpD 0.3145 0.2814 1
Brugia malayi Latrophilin receptor protein 2 0.0083 0.0063 0.1398
Brugia malayi Serotonin receptor 0.0033 0.0018 0.04
Leishmania major hydrolase, alpha/beta fold family, putative 0.0027 0.0013 0.1067
Loa Loa (eye worm) hypothetical protein 0.0078 0.0058 0.129
Loa Loa (eye worm) hypothetical protein 0.0033 0.0018 0.04
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0023 0.0009 0.0751
Loa Loa (eye worm) HAD-superfamily hydrolase 0.0026 0.0011 0.0251
Schistosoma mansoni hypothetical protein 0.0083 0.0063 0.0298
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0133
Schistosoma mansoni hypothetical protein 0.0083 0.0063 0.0298
Echinococcus multilocularis neuropeptide Y receptor 0.0033 0.0018 0.0018
Entamoeba histolytica hypothetical protein 0.0117 0.0094 0.0962
Echinococcus granulosus rhodopsin orphan GPCR 0.0033 0.0018 0.0018
Mycobacterium ulcerans DNA polymerase IV 0.0141 0.0115 0.0113
Loa Loa (eye worm) hypothetical protein 0.0033 0.0018 0.04
Echinococcus multilocularis neuropeptide s receptor 0.0485 0.0424 0.0424
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0021 0.0007 0.0018
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0022 0.0008 0.0168
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0083 0.0063 0.0063
Loa Loa (eye worm) haloacid dehalogenase-like hydrolase 0.0026 0.0011 0.0251
Toxoplasma gondii histone lysine methyltransferase SET1 0.0058 0.0041 0.3396
Wolbachia endosymbiont of Brugia malayi ATP-dependent exoDNAse (exonuclease V) beta subunit, RecB 0.0038 0.0023 0.4346
Trypanosoma cruzi importin beta-1 subunit, putative 0.0024 0.0009 0.079
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0023 0.0009 0.0751
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0055 0.0037 0.0176
Echinococcus multilocularis fmrfamide receptor 0.0033 0.0018 0.0018
Onchocerca volvulus Lipase homolog 0.0027 0.0013 0.03
Mycobacterium ulcerans haloalkane dehalogenase 0.0027 0.0013 0.001
Echinococcus multilocularis microtubule associated protein 2 0.0723 0.0638 0.0638
Trypanosoma brucei heat shock protein, putative 0.0032 0.0017 0.1414
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0062 0.0044 0.3668
Leishmania major hypothetical protein, conserved 0.0146 0.012 1
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.0021 0.0007 0.0076
Trichomonas vaginalis 2-deoxyglucose-6-phosphate phosphatase, putative 0.0026 0.0011 0.0267
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0079 0.0059 0.0183
Trichomonas vaginalis D-aminoacylase, putative 0.0146 0.012 0.2809
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0007 0.0173
Entamoeba histolytica HAD hydrolase, family IA, variant 3 0.0026 0.0011 0.0117
Brugia malayi Isocitrate dehydrogenase 0.0035 0.002 0.0432
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0044 0.0028 0.2317
Brugia malayi HAD-superfamily hydrolase, subfamily IA, variant 3 containing protein 0.0026 0.0011 0.0251
Leishmania major hydrolase, alpha/beta fold family-like protein 0.0027 0.0013 0.1067
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0033 0.0018 0.0018
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0022 0.0008 0.0168
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0044 0.0028 0.2317
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0033 0.0018 0.0085
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0023 0.0009 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0007 0.0173
Loa Loa (eye worm) oxidoreductase 0.0023 0.0009 0.0198
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0133
Loa Loa (eye worm) hydrolase 0.0027 0.0013 0.0282
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0141 0.0115 0.2549
Trypanosoma brucei DNA polymerase IV, putative 0.0141 0.0115 0.9647
Plasmodium vivax hypothetical protein, conserved 0.003 0.0015 0.1293
Entamoeba histolytica deoxycytidyl transferase, putative 0.0141 0.0115 0.1186
Schistosoma mansoni topbp1 0.0021 0.0007 0.0035
Mycobacterium ulcerans DNA polymerase IV 0.0141 0.0115 0.0113
Mycobacterium tuberculosis Possible epoxide hydrolase EphE (epoxide hydratase) (arene-oxide hydratase) 0.0027 0.0013 0.0007
Onchocerca volvulus 0.0023 0.0009 0.0211
Leishmania major hypothetical protein, conserved 0.0015 0.0002 0.0137
Schistosoma mansoni hydrolase 0.0027 0.0013 0.006
Echinococcus multilocularis GPCR, family 2 0.0083 0.0063 0.0063
Schistosoma mansoni bromodomain containing protein 0.0063 0.0045 0.0212
Loa Loa (eye worm) HAD-superfamily hydrolase 0.0026 0.0011 0.0251
Echinococcus granulosus jumonji domain containing protein 0.0042 0.0026 0.0026
Onchocerca volvulus Lipase homolog 0.0027 0.0013 0.03
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0022 0.0008 0.0008
Echinococcus multilocularis rhodopsin orphan GPCR 0.0033 0.0018 0.0018
Brugia malayi Endoplasmin precursor 0.0032 0.0017 0.0374
Trichomonas vaginalis importin beta-1, putative 0.0024 0.0009 0.0222
Loa Loa (eye worm) hypothetical protein 0.0079 0.0059 0.13
Trichomonas vaginalis replication factor C large subunit, putative 0.0021 0.0007 0.0173
Leishmania major heat shock protein 83-1 0.0032 0.0017 0.1414
Brugia malayi RE15519p 0.0033 0.0018 0.04
Onchocerca volvulus 0.0022 0.0008 0.0179
Plasmodium vivax replication factor C subunit 1, putative 0.0021 0.0007 0.0616
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0079 0.0059 0.0056
Echinococcus granulosus tm gpcr rhodopsin 0.0033 0.0018 0.0018
Brugia malayi haloacid dehalogenase-like hydrolase family protein 0.0026 0.0011 0.0251
Echinococcus multilocularis heat shock protein 90 0.0032 0.0017 0.0017
Trypanosoma cruzi DNA polymerase kappa, putative 0.0141 0.0115 0.9647
Loa Loa (eye worm) hypothetical protein 0.0033 0.0018 0.04
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0024 0.0009 0.0009
Schistosoma mansoni zinc finger protein 0.0021 0.0007 0.0032
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0023 0.0009 0.0006
Onchocerca volvulus 0.0109 0.0086 0.2017
Loa Loa (eye worm) hypothetical protein 0.0033 0.0018 0.04
Loa Loa (eye worm) endoplasmin 0.0032 0.0017 0.0374
Loa Loa (eye worm) hypothetical protein 0.0033 0.0018 0.04
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.0028 0.2317
Echinococcus granulosus peptide allatostatin:somatostatin 0.0033 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0013 0 0.0006
Onchocerca volvulus 0.002 0.0006 0.0142
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0019 0.0006 0.0479
Echinococcus granulosus tachykinin peptides receptor 99D 0.0033 0.0018 0.0018
Trichomonas vaginalis endoplasmin, putative 0.002 0.0006 0.0137
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0141 0.0115 0.0542
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0022 0.0008 0.0008
Plasmodium vivax ubiquitin-conjugating enzyme E2 N, putative 0.0083 0.0063 0.5279
Echinococcus multilocularis isocitrate dehydrogenase 0.0035 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0127
Echinococcus multilocularis rhodopsin orphan GPCR 0.0033 0.0018 0.0018
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.7169 0.643 0.643
Trypanosoma brucei DNA damage repair protein, putative 0.0044 0.0028 0.2317
Echinococcus granulosus Niemann Pick C1 protein 0.0326 0.0281 0.0281
Schistosoma mansoni hypothetical protein 0.0083 0.0063 0.0298
Echinococcus multilocularis dna polymerase kappa 0.0141 0.0115 0.0115
Mycobacterium tuberculosis Probable thymidine phosphorylase DeoA (tdrpase) (pyrimidine phosphorylase) 1.1143 1 1
Brugia malayi Tachykinin-like peptides receptor 99D 0.0033 0.0018 0.04
Schistosoma mansoni neuropeptide F-like receptor 0.0033 0.0018 0.0085
Leishmania major heat shock protein 83-1 0.0032 0.0017 0.1414
Mycobacterium tuberculosis Probable oxidoreductase 0.0027 0.0013 0.0007
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0033 0.0018 0.0018
Echinococcus granulosus hypothetical protein 0.0038 0.0023 0.0023
Schistosoma mansoni neuropeptide receptor 0.0033 0.0018 0.0085
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0079 0.0059 0.0056
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0023 0.0009 0.0003
Echinococcus granulosus neuropeptide Y receptor 0.0033 0.0018 0.0018
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0105 0.0083 0.1833
Trypanosoma brucei ATP-dependent DNA helicase, putative 0.0016 0.0003 0.0228
Onchocerca volvulus 0.0033 0.0018 0.0425
Schistosoma mansoni family S33 non-peptidase homologue (S33 family) 0.0027 0.0013 0.006
Toxoplasma gondii ABC1 family protein 0.0146 0.012 1
Loa Loa (eye worm) jmjC domain-containing protein 0.004 0.0024 0.0537
Trichomonas vaginalis penicillin-binding protein, putative 0.0146 0.012 0.2809
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0146 0.012 0.0562
Trichomonas vaginalis hydrolase, putative 0.0027 0.0013 0.03
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0023 0.0009 0.0003
Trypanosoma cruzi hydrolase-like protein, putative 0.0027 0.0013 0.1067
Loa Loa (eye worm) TYRA-2 protein 0.0033 0.0018 0.04
Trichomonas vaginalis D-aminoacylase, putative 0.0146 0.012 0.2809
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0023 0.0009 0.0009
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0079 0.0059 0.0053
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0035 0.002 0.1636
Brugia malayi hypothetical protein 0.0033 0.0018 0.04
Brugia malayi ImpB/MucB/SamB family protein 0.0141 0.0115 0.2549
Leishmania major DNA polymerase kappa, putative 0.0141 0.0115 0.9647
Mycobacterium ulcerans hypothetical protein 0.0044 0.0028 0.0025
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0009 0.0006
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0022 0.0008 0.0008
Brugia malayi Patched family protein 0.002 0.0006 0.0133
Trichomonas vaginalis 2-deoxyglucose-6-phosphate phosphatase, putative 0.0026 0.0011 0.0267
Brugia malayi heat shock protein 90 0.0032 0.0017 0.0374
Loa Loa (eye worm) hypothetical protein 0.0033 0.0018 0.04
Trypanosoma cruzi PAB1-binding protein , putative 0.0078 0.0058 0.4883
Wolbachia endosymbiont of Brugia malayi superfamily I DNA/RNA helicase 0.0038 0.0023 0.4346
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0141 0.0115 0.0109
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0046 0.0215
Brugia malayi Pre-SET motif family protein 0.0428 0.0373 0.8234
Brugia malayi Bloom's syndrome protein homolog 0.0019 0.0006 0.0127
Schistosoma mansoni hypothetical protein 0.0035 0.002 0.0093
Trypanosoma cruzi hypothetical protein, conserved 0.0027 0.0013 0.1067
Schistosoma mansoni DNA helicase recq5 0.0019 0.0006 0.0027
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0133
Schistosoma mansoni opsin-like receptor 0.0033 0.0018 0.0085
Echinococcus multilocularis peregrin 0.0033 0.0018 0.0018
Echinococcus multilocularis abhydrolase domain containing protein 16A 0.0027 0.0013 0.0013
Brugia malayi Myosin head containing protein 0.002 0.0006 0.0133
Echinococcus multilocularis thyroid hormone receptor alpha 0.0022 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0146 0.012 0.2642
Entamoeba histolytica heat shock protein 90, putative 0.0032 0.0017 0.0174
Echinococcus multilocularis neuropeptides capa receptor 0.0033 0.0018 0.0018
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0033 0.0018 0.0085
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0027 0.0013 0.03
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0033 0.0018 0.0018
Echinococcus multilocularis expressed conserved protein 0.0306 0.0263 0.0263
Mycobacterium ulcerans epoxide hydrolase EphA 0.0993 0.0881 0.0878
Toxoplasma gondii UvrD/REP helicase domain-containing protein 0.0038 0.0023 0.1905
Entamoeba histolytica hypothetical protein 0.0117 0.0094 0.0962
Mycobacterium leprae Probable ATP dependent DNA helicase UvrD1 0.0038 0.0023 0.0055
Mycobacterium tuberculosis Probable exonuclease V (beta chain) RecB (exodeoxyribonuclease V beta chain)(exodeoxyribonuclease V polypeptide) (chi-specific e 0.0411 0.0357 0.0351
Echinococcus granulosus rhodopsin orphan GPCR 0.0033 0.0018 0.0018
Trypanosoma brucei DNA polymerase kappa, putative 0.0141 0.0115 0.9647
Brugia malayi RNA binding protein 0.0064 0.0046 0.1009
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0023 0.0009 0.0198
Mycobacterium ulcerans lipase/esterase 0.0027 0.0013 0.001
Schistosoma mansoni neuropeptide f receptor 76f 0.0033 0.0018 0.0085
Treponema pallidum DNA helicase II (uvrD) 0.0038 0.0023 0.4346
Entamoeba histolytica haloacid dehalogenase-like hydrolase domain-containing protein 0.0026 0.0011 0.0117
Echinococcus granulosus fmrfamide receptor 0.0033 0.0018 0.0018
Echinococcus multilocularis ecdysone induced protein 78C 0.0022 0.0008 0.0008
Mycobacterium tuberculosis Possible epoxide hydrolase EphF (epoxide hydratase) (arene-oxide hydratase) 0.0027 0.0013 0.0007
Brugia malayi Patched family protein 0.002 0.0006 0.0133
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0011 0.0267
Leishmania major heat shock protein 83-1 0.0032 0.0017 0.1414
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0033 0.0018 0.0085
Mycobacterium tuberculosis Conserved protein 0.0146 0.012 0.0114
Trypanosoma brucei DNA polymerase IV, putative 0.0141 0.0115 0.9647
Mycobacterium ulcerans homoserine O-acetyltransferase 0.0027 0.0013 0.001
Trypanosoma cruzi Heat shock protein 83, putative 0.0032 0.0017 0.1414
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0022 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0033 0.0018 0.04
Mycobacterium tuberculosis Probable anthranilate phosphoribosyltransferase TrpD 0.3145 0.2814 0.281
Loa Loa (eye worm) hypothetical protein 0.0033 0.0018 0.04
Brugia malayi nuclear hormone receptor 0.0022 0.0008 0.0168
Loa Loa (eye worm) PHD-finger family protein 0.002 0.0006 0.0139
Loa Loa (eye worm) hypothetical protein 0.0033 0.0018 0.04
Echinococcus granulosus survival motor neuron protein 1 0.0517 0.0453 0.0453
Leishmania major 4-coumarate:coa ligase-like protein 0.0079 0.0059 0.4919
Trypanosoma cruzi DNA damage repair protein, putative 0.0044 0.0028 0.2317
Loa Loa (eye worm) HAD-superfamily hydrolase 0.0026 0.0011 0.0251
Trypanosoma cruzi DNA damage repair protein, putative 0.0044 0.0028 0.2317
Schistosoma mansoni neuropeptide F-like receptor 0.0033 0.0018 0.0085
Loa Loa (eye worm) hypothetical protein 0.0033 0.0018 0.04
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.0015 0.1293
Onchocerca volvulus 0.0033 0.0018 0.0425
Brugia malayi GnHR receptor homolog 0.0033 0.0018 0.04
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0061 0.0043 0.004
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0055 0.0038 0.0032
Onchocerca volvulus 0.002 0.0006 0.0142
Entamoeba histolytica hypothetical protein 0.0026 0.0011 0.0117
Brugia malayi haloacid dehalogenase-like hydrolase family protein 0.0026 0.0011 0.0251
Echinococcus multilocularis serotonin receptor 0.0033 0.0018 0.0018
Echinococcus multilocularis heat shock protein 90 0.0025 0.0011 0.0011
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0022 0.0008 0.0008
Trypanosoma brucei unspecified product 0.0141 0.0115 0.9647
Echinococcus multilocularis importin subunit beta 1 0.0029 0.0014 0.0014
Trypanosoma cruzi heat shock protein 90, putative 0.0032 0.0017 0.1414
Loa Loa (eye worm) hypothetical protein 0.0033 0.0018 0.04
Trypanosoma cruzi heat shock protein 85, putative 0.0032 0.0017 0.1414
Echinococcus multilocularis abhydrolase domain containing protein 11 0.0027 0.0013 0.0013
Echinococcus multilocularis g protein coupled receptor 0.0033 0.0018 0.0018
Schistosoma mansoni DNA polymerase IV / kappa 0.0044 0.0028 0.013
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.014 0.0114 0.2519
Loa Loa (eye worm) PHD-finger family protein 0.003 0.0015 0.0342
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0009 0.0006
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0011 0.0267
Echinococcus multilocularis zinc finger protein 0.0021 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0133
Brugia malayi ORL1-like opioid receptor 0.0033 0.0018 0.04
Brugia malayi G protein-coupled receptor 0.0033 0.0018 0.04
Loa Loa (eye worm) hypothetical protein 0.0059 0.0041 0.0906
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0133
Echinococcus multilocularis G protein coupled receptor 139 0.0033 0.0018 0.0018
Onchocerca volvulus 0.002 0.0006 0.0142
Mycobacterium ulcerans exported protease 0.0027 0.0013 0.001
Schistosoma mansoni neuropeptide receptor 0.0033 0.0018 0.0085
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0009 0.0006
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0033 0.0018 0.04
Loa Loa (eye worm) hypothetical protein 0.0022 0.0008 0.0168
Brugia malayi hypothetical protein 0.0033 0.0018 0.04
Wolbachia endosymbiont of Brugia malayi phosphatase 0.0026 0.0011 0.1124
Mycobacterium tuberculosis Probable haloalkane dehalogenase 0.0027 0.0013 0.0007
Echinococcus multilocularis orexin receptor type 2 0.0033 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0033 0.0018 0.04
Echinococcus granulosus sex peptide receptor 0.0033 0.0018 0.0018
Echinococcus granulosus dna polymerase eta 0.0141 0.0115 0.0115
Echinococcus multilocularis survival motor neuron protein 1 0.0517 0.0453 0.0453
Entamoeba histolytica hypothetical protein 0.0026 0.0011 0.0117
Brugia malayi Patched related family protein 4 0.002 0.0006 0.0133
Schistosoma mansoni microtubule-associated protein tau 0.0723 0.0638 0.2999
Chlamydia trachomatis exodeoxyribonuclease V subunit gamma 0.1286 0.1144 1
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0022 0.0008 0.0036
Loa Loa (eye worm) hypothetical protein 0.0044 0.0028 0.0612
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0059 0.0041 0.0041
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0033 0.0018 0.0018
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0033 0.0018 0.0085
Loa Loa (eye worm) hypothetical protein 0.0033 0.0018 0.04
Echinococcus granulosus sterol regulatory element binding protein 0.014 0.0114 0.0114
Echinococcus granulosus replication factor c subunit 1 0.0021 0.0007 0.0007
Schistosoma mansoni opsin-like receptor 0.0033 0.0018 0.0085
Mycobacterium tuberculosis Probable ATP-dependent DNA helicase 0.0077 0.0057 0.0051
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0009 0.0006
Echinococcus granulosus neuropeptide FF receptor 2 0.0033 0.0018 0.0018
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0117 0.0094 0.0094
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0025 0.0011 0.0011
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0023 0.0009 0.0003
Brugia malayi hypothetical protein 0.0033 0.0018 0.04
Trichomonas vaginalis 2-deoxyglucose-6-phosphate phosphatase, putative 0.0026 0.0011 0.0267
Echinococcus multilocularis dna polymerase eta 0.0141 0.0115 0.0115
Loa Loa (eye worm) hypothetical protein 0.0146 0.012 0.2642
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0035 0.002 0.1636
Loa Loa (eye worm) neuropeptide F receptor 0.0033 0.0018 0.04
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0019 0.0006 0.0127
Brugia malayi Bromodomain containing protein 0.0037 0.0022 0.0481
Trypanosoma cruzi DNA polymerase kappa, putative 0.0141 0.0115 0.9647
Loa Loa (eye worm) hypothetical protein 0.0052 0.0035 0.0771
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0033 0.0018 0.0085
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0061 0.0043 0.0043
Trypanosoma cruzi ISWI complex protein 0.0015 0.0002 0.0137
Trypanosoma cruzi DNA polymerase kappa, putative 0.0141 0.0115 0.9647
Echinococcus granulosus ecdysone induced protein 78C 0.0022 0.0008 0.0008
Mycobacterium ulcerans acetyl-CoA synthetase 0.0023 0.0009 0.0006
Schistosoma mansoni ran 0.0021 0.0007 0.0035
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0009 0.0222
Echinococcus granulosus fetal alzheimer antigen falz 0.0024 0.0009 0.0009
Echinococcus multilocularis fmrfamide receptor 0.0033 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0133
Brugia malayi Patched family protein 0.002 0.0006 0.0133
Brugia malayi Melatonin receptor type 1A 0.0033 0.0018 0.04
Mycobacterium leprae POSSIBLE SECRETED PROTEASE 0.0027 0.0013 0.0019
Plasmodium falciparum ataxin-2 like protein, putative 0.0078 0.0058 0.9249
Onchocerca volvulus 0.002 0.0006 0.0142
Schistosoma mansoni ap endonuclease 0.0061 0.0043 0.0201
Brugia malayi Patched protein homolog 1 0.002 0.0006 0.0133
Loa Loa (eye worm) hypothetical protein 0.018 0.015 0.3322
Trypanosoma brucei heat shock protein, putative 0.0032 0.0017 0.1414
Echinococcus granulosus microtubule associated protein 2 0.0723 0.0638 0.0638
Schistosoma mansoni survival motor neuron protein 0.0105 0.0083 0.039
Schistosoma mansoni biogenic amine (5HT) receptor 0.0033 0.0018 0.0085
Loa Loa (eye worm) G-protein coupled receptor 0.0033 0.0018 0.04
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0044 0.0028 0.2317
Trypanosoma cruzi hydrolase-like protein, putative 0.0027 0.0013 0.1067
Schistosoma mansoni DNA helicase recq1 0.0019 0.0006 0.0027
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0035 0.002 0.002
Leishmania major heat shock protein 83-1 0.0032 0.0017 0.1414
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0033 0.0018 0.04
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0146 0.012 0.0562
Loa Loa (eye worm) hypothetical protein 0.0022 0.0008 0.0168
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0033 0.0018 0.0085
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0019 0.0006 0.0479
Plasmodium falciparum importin beta, putative 0.0029 0.0014 0.2279
Echinococcus multilocularis g protein coupled receptor 0.0033 0.0018 0.0018
Plasmodium vivax hypothetical protein, conserved 0.0027 0.0013 0.1067
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0061 0.0043 0.3582
Echinococcus granulosus beta LACTamase domain containing family member 0.0146 0.012 0.012
Brugia malayi Serotonin receptor 0.0033 0.0018 0.04
Brugia malayi Patched family protein 0.002 0.0006 0.0133
Loa Loa (eye worm) hypothetical protein 0.0033 0.0018 0.04
Toxoplasma gondii LsmAD domain-containing protein 0.0078 0.0058 0.4883
Echinococcus multilocularis tumor protein p63 0.0742 0.0655 0.0655
Onchocerca volvulus Protein patched homolog 0.002 0.0006 0.0142
Schistosoma mansoni hypothetical protein 0.0135 0.0109 0.0515
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0027 0.0013 0.03
Plasmodium vivax DNA repair protein REV1, putative 0.0044 0.0028 0.2317
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0023 0.0009 0.0006
Mycobacterium tuberculosis Probable esterase LipL 0.0146 0.012 0.0114
Echinococcus granulosus allatostatin A receptor 0.0033 0.0018 0.0018
Trichomonas vaginalis heat shock protein, putative 0.0032 0.0017 0.0397
Echinococcus granulosus rhodopsin orphan GPCR 0.0033 0.0018 0.0018
Brugia malayi topoisomerase 0.0021 0.0007 0.0163
Schistosoma mansoni thyroid hormone receptor 0.0022 0.0008 0.0036
Loa Loa (eye worm) hypothetical protein 0.0033 0.0018 0.04
Leishmania major importin beta-1 subunit, putative 0.0024 0.0009 0.079
Leishmania major pantothenate kinase subunit, putative 0.0015 0.0002 0.018
Trypanosoma cruzi heat shock protein 85, putative 0.0032 0.0017 0.1414
Onchocerca volvulus 0.002 0.0006 0.0142
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0019 0.0006 0.0006
Brugia malayi Importin beta-1 subunit 0.0029 0.0014 0.0318
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0133
Schistosoma mansoni DNA ligase IV 0.0021 0.0007 0.0035
Trypanosoma cruzi BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0021 0.0007 0.0616
Brugia malayi AKH receptor 0.0033 0.0018 0.04
Trypanosoma brucei hydrolase, alpha/beta fold family, putative 0.0027 0.0013 0.1067
Mycobacterium ulcerans hypothetical protein 0.0027 0.0013 0.001
Schistosoma mansoni hypothetical protein 0.0135 0.0109 0.0515
Echinococcus granulosus ubiquitin conjugating enzyme E2 N 0.0083 0.0063 0.0063
Schistosoma mansoni chromosome transmission fidelity factor 0.0021 0.0007 0.0035
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0061 0.0043 0.0384
Schistosoma mansoni ubiquitin conjugating enzyme 13 0.0083 0.0063 0.0297
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0007 0.0165
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0133
Brugia malayi hydrolase, alpha/beta fold family protein 0.0027 0.0013 0.0282
Echinococcus multilocularis allatostatin A receptor 0.0033 0.0018 0.0018
Entamoeba histolytica heat shock protein 90, putative 0.0032 0.0017 0.0174
Brugia malayi Patched family protein 0.002 0.0006 0.0133
Brugia malayi hypothetical protein 0.0033 0.0018 0.04
Trichomonas vaginalis DNA helicase recq1, putative 0.0019 0.0006 0.0135
Trichomonas vaginalis 2-deoxyglucose-6-phosphate phosphatase, putative 0.0026 0.0011 0.0267
Loa Loa (eye worm) hypothetical protein 0.0078 0.0059 0.1299
Leishmania major heat shock protein 83-1 0.0032 0.0017 0.1414
Trypanosoma cruzi hypothetical protein, conserved 0.0146 0.012 1
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0033 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0133
Mycobacterium ulcerans thymidine phosphorylase 1.1143 1 1
Echinococcus granulosus neuropeptide receptor 0.0033 0.0018 0.0018
Brugia malayi G-protein coupled receptor 0.0033 0.0018 0.04
Loa Loa (eye worm) hypothetical protein 0.0128 0.0104 0.2288
Leishmania major ubiquitin-conjugating enzyme e2, putative 0.0083 0.0063 0.5279
Echinococcus multilocularis dnaJ subfamily B 0.0404 0.0351 0.0351
Loa Loa (eye worm) hypothetical protein 0.0021 0.0007 0.0163
Entamoeba histolytica hypothetical protein 0.0027 0.0013 0.0131
Mycobacterium tuberculosis Probable ATP-dependent DNA helicase II UvrD1 0.0038 0.0023 0.0017
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0022 0.0008 0.0168
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0079 0.0059 0.0053
Loa Loa (eye worm) hypothetical protein 0.0033 0.0018 0.04
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0007 0.0626
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0035 0.002 0.002
Trypanosoma cruzi ATP-dependent DNA helicase, putative 0.0038 0.0023 0.1905
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0023 0.0009 0.0751
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0011 0.0267
Mycobacterium tuberculosis Possible peroxidase BpoB (non-haem peroxidase) 0.0027 0.0013 0.0007
Schistosoma mansoni hypothetical protein 0.0033 0.0018 0.0085
Schistosoma mansoni 2-deoxyglucose-6-phosphate phosphatase 0.0026 0.0011 0.0053
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0078 0.0059 0.0276
Loa Loa (eye worm) hypothetical protein 0.0059 0.0041 0.0906
Chlamydia trachomatis phosphoglycolate phosphatase 0.0026 0.0011 0.0035
Entamoeba histolytica alpha/beta hydrolase fold protein, putative 0.0027 0.0013 0.0131
Mycobacterium ulcerans hypothetical protein 0.0026 0.0011 0.0009
Trypanosoma brucei DNA polymerase kappa, putative 0.0141 0.0115 0.9647
Echinococcus multilocularis rhodopsin orphan GPCR 0.0033 0.0018 0.0018
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0007 0.0173
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0083 0.0063 0.1398
Schistosoma mansoni neuropeptide receptor 0.0033 0.0018 0.0085
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0133
Loa Loa (eye worm) patched family protein 0.002 0.0006 0.0133
Toxoplasma gondii hypothetical protein 0.0064 0.0046 0.3849
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0022 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0033 0.0018 0.04
Onchocerca volvulus 0.0026 0.0011 0.0267
Brugia malayi haloacid dehalogenase-like hydrolase family protein 0.0026 0.0011 0.0251
Echinococcus multilocularis heat shock protein 0.0032 0.0017 0.0017
Echinococcus multilocularis neuropeptide Y receptor 0.0033 0.0018 0.0018
Mycobacterium ulcerans epoxide hydrolase EphE 0.0027 0.0013 0.001
Giardia lamblia Replication factor C, subunit 1 0.0021 0.0007 0.0017
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0014 0.1203
Brugia malayi Pax transcription activation domain interacting protein 0.0021 0.0007 0.0163
Trichomonas vaginalis DNA helicase recq, putative 0.0019 0.0006 0.0135
Giardia lamblia Hydrolase, putative 0.0026 0.0011 0.0058
Echinococcus multilocularis lysosomal acid lipase:cholesteryl ester 0.0027 0.0013 0.0013
Brugia malayi hydrolase, alpha/beta fold family protein 0.0027 0.0013 0.0282
Loa Loa (eye worm) hypothetical protein 0.0029 0.0014 0.0318
Trypanosoma brucei heat shock protein, putative 0.0032 0.0017 0.1414
Trichomonas vaginalis 2-deoxyglucose-6-phosphate phosphatase, putative 0.0026 0.0011 0.0267
Mycobacterium tuberculosis Probable exported protease 0.0027 0.0013 0.0007
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0035 0.002 0.0092
Trypanosoma brucei ubiquitin-protein ligase, putative 0.0083 0.0063 0.5279
Brugia malayi G protein-coupled receptor F59B2.13 0.0033 0.0018 0.04
Echinococcus multilocularis protein patched 0.014 0.0114 0.0114
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0023 0.0009 0.0198
Echinococcus granulosus endoplasmin 0.0025 0.0011 0.0011
Brugia malayi PHD-finger family protein 0.0013 0 0.0006
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0019 0.0006 0.0026
Brugia malayi Patched family protein 0.002 0.0006 0.0133
Onchocerca volvulus Protein patched homolog 0.002 0.0006 0.0142
Toxoplasma gondii ubiquitin-conjugating enzyme subfamily protein 0.0083 0.0063 0.5279
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0003 0.0015
Loa Loa (eye worm) hypothetical protein 0.0037 0.0022 0.0482
Echinococcus granulosus heat shock protein 90 0.0032 0.0017 0.0017
Echinococcus multilocularis neuropeptide receptor A26 0.0485 0.0424 0.0424
Brugia malayi Patched family protein 0.002 0.0006 0.0133
Loa Loa (eye worm) hypothetical protein 0.0128 0.0104 0.2288
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0133
Loa Loa (eye worm) abhydrolase domain-containing protein 2 0.0027 0.0013 0.0282
Entamoeba histolytica hypothetical protein 0.0117 0.0094 0.0962
Mycobacterium ulcerans hypothetical protein 0.0026 0.0011 0.0009
Schistosoma mansoni patched 1 0.014 0.0114 0.0536
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0064 0.0046 0.1009
Schistosoma mansoni acetyl-CoA synthetase 0.0023 0.0009 0.0042
Schistosoma mansoni importin beta-1 0.0029 0.0014 0.0068
Brugia malayi hypothetical protein 0.0128 0.0104 0.2288
Brugia malayi Dopamine receptor protein 1 0.0033 0.0018 0.04
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0035 0.002 0.002
Echinococcus granulosus rhodopsin orphan GPCR 0.0033 0.0018 0.0018
Entamoeba histolytica hypothetical protein 0.0024 0.0009 0.0097
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.0021 0.0007 0.0616
Giardia lamblia Heat shock protein HSP 90-alpha 0.0025 0.0011 0.0055
Echinococcus multilocularis abhydrolase domain containing protein 0.0027 0.0013 0.0013
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0022 0.0008 0.0179
Loa Loa (eye worm) hypothetical protein 0.0079 0.0059 0.13
Brugia malayi G-protein coupled receptor 0.0033 0.0018 0.04
Loa Loa (eye worm) hypothetical protein 0.0059 0.0041 0.0906
Schistosoma mansoni biogenic amine receptor 0.0033 0.0018 0.0085
Trypanosoma brucei DNA damage repair protein, putative 0.0044 0.0028 0.2317
Loa Loa (eye worm) hypothetical protein 0.0033 0.0018 0.04
Loa Loa (eye worm) hypothetical protein 0.0027 0.0013 0.0282
Mycobacterium ulcerans acyl-CoA synthetase 0.0079 0.0059 0.0056
Leishmania major heat shock protein 83-1 0.0032 0.0017 0.1414
Trypanosoma brucei DNA polymerase eta, putative 0.0141 0.0115 0.9647
Chlamydia trachomatis exodeoxyribonuclease V subunit beta 0.0372 0.0323 0.2775
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0023 0.0009 0.0003
Echinococcus granulosus tar DNA binding protein 0.0064 0.0046 0.0046
Loa Loa (eye worm) hypothetical protein 0.0059 0.0041 0.0906
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 0.0083 0.0063 0.1395
Toxoplasma gondii exonuclease III APE 0.0061 0.0043 0.3582
Brugia malayi PHD-finger family protein 0.003 0.0015 0.0342
Onchocerca volvulus 0.0487 0.0426 1
Treponema pallidum heat shock protein 90 0.0025 0.0011 0.1046
Giardia lamblia DNA repair protein RAD52 0.1095 0.0973 1
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0046 0.0215
Loa Loa (eye worm) hypothetical protein 0.0033 0.0018 0.04
Loa Loa (eye worm) hypothetical protein 0.0033 0.0018 0.04
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.0007 0.0626
Mycobacterium ulcerans acyl-CoA synthetase 0.003 0.0016 0.0013
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0021 0.0007 0.0616
Brugia malayi ImpB/MucB/SamB family protein 0.0141 0.0115 0.2549
Onchocerca volvulus 0.0033 0.0018 0.0425
Brugia malayi hypothetical protein 0.0021 0.0007 0.0163
Onchocerca volvulus Mitochondrial genome maintenance exonuclease 1 homolog 0.0038 0.0023 0.0536
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0061 0.0043 1
Mycobacterium ulcerans hydrolase 0.0026 0.0011 0.0009
Trypanosoma cruzi glycosyl hydrolase, putative 0.0026 0.0011 0.095
Toxoplasma gondii patched family protein 0.002 0.0006 0.0504
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0133
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0027 0.0013 0.03
Echinococcus granulosus neuropeptides capa receptor 0.0033 0.0018 0.0018
Treponema pallidum ATP-dependent nuclease, subunit A 0.0038 0.0023 0.4346
Brugia malayi AMP-binding enzyme family protein 0.0079 0.0059 0.13
Leishmania major heat shock protein 83-1 0.0032 0.0017 0.1414
Schistosoma mansoni amine GPCR 0.0033 0.0018 0.0085
Trichomonas vaginalis esterase, putative 0.0146 0.012 0.2809
Leishmania major heat shock protein 83-1 0.0032 0.0017 0.1414
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0133
Entamoeba histolytica recQ family helicase, putative 0.0019 0.0006 0.0059
Schistosoma mansoni amine GPCR 0.0033 0.0018 0.0085
Trichomonas vaginalis set domain proteins, putative 0.0487 0.0426 1
Entamoeba histolytica Rad52/22 family double-strand break repair protein, putative 0.0312 0.0268 0.2759
Trypanosoma brucei Heat shock protein 83, putative 0.0032 0.0017 0.1414
Mycobacterium ulcerans exported protease 0.0027 0.0013 0.001
Mycobacterium leprae Possible short-chain dehydrogenase EphD 0.0027 0.0013 0.0019
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0146 0.012 0.0114
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0011 0.0267
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.0007 0.0007
Plasmodium falciparum ATP-dependent DNA helicase UvrD 0.0038 0.0023 0.3609
Loa Loa (eye worm) steroid hormone receptor 0.0022 0.0008 0.0168
Brugia malayi polk-prov protein 0.0044 0.0028 0.0612
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0061 0.0043 0.3582
Trichomonas vaginalis 2-deoxyglucose-6-phosphate phosphatase, putative 0.0026 0.0011 0.0267
Mycobacterium tuberculosis Probable homoserine O-acetyltransferase MetA (homoserine O-trans-acetylase) (homoserine transacetylase) (HTA) 0.0027 0.0013 0.0007
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0022 0.0008 0.0168
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0023 0.0009 0.0092
Loa Loa (eye worm) hypothetical protein 0.0027 0.0013 0.0282
Echinococcus multilocularis abhydrolase domain containing 3 0.0027 0.0013 0.0013
Loa Loa (eye worm) MH2 domain-containing protein 0.0122 0.0098 0.2156
Mycobacterium tuberculosis Conserved hypothetical protein 0.0026 0.0011 0.0005
Brugia malayi Patched related family protein 10 0.002 0.0006 0.0133
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0033 0.0018 0.0085
Mycobacterium tuberculosis Probable lipase LipD 0.0146 0.012 0.0114
Giardia lamblia DINP protein human, muc B family 0.0141 0.0115 0.1134
Echinococcus granulosus lysine specific demethylase 5A 0.004 0.0024 0.0024
Brugia malayi AMP-binding enzyme family protein 0.0079 0.0059 0.13
Leishmania major DNA polymerase kappa, putative 0.0044 0.0028 0.2317
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0014 0.0303
Echinococcus granulosus somatostatin receptor 0.0033 0.0018 0.0018
Chlamydia trachomatis exodeoxyribonuclease V subunit alpha 0.0611 0.0538 0.4665
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0023 0.0009 0.0003
Onchocerca volvulus 0.0146 0.012 0.2809
Loa Loa (eye worm) bromodomain containing protein 0.0017 0.0004 0.0082
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0055 0.0038 0.0032
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0055 0.0037 0.0176
Mycobacterium ulcerans oxidoreductase 0.0027 0.0013 0.001
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0133
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0033 0.0018 0.04
Trypanosoma brucei DNA polymerase kappa, putative 0.0141 0.0115 0.9647
Trichomonas vaginalis heat shock protein, putative 0.0025 0.0011 0.026
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.0028 0.2317
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0033 0.0018 0.0085
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0022 0.0008 0.0008
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0023 0.0009 0.0003
Echinococcus multilocularis g protein coupled receptor 0.0033 0.0018 0.0018
Echinococcus granulosus 7TM GPCR rhodopsin 0.0033 0.0018 0.0018
Echinococcus multilocularis FTZ F1 alpha 0.0022 0.0008 0.0008
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0055 0.0038 0.0032
Brugia malayi Steroid receptor seven-up type 2 0.0022 0.0008 0.0168
Echinococcus multilocularis neuropeptide FF receptor 2 0.0033 0.0018 0.0018

Activities

Activity type Activity value Assay description Source Reference
CCh (functional) = 33 % Maximal response obtained for each drug normalized to effect of carbachol in Muscarinic acetylcholine receptor M2 ChEMBL. 9651157
CCh (functional) = 51 % Maximal response obtained for each drug normalized to effect of carbachol in Muscarinic acetylcholine receptor M1 ChEMBL. 9651157
CCh (functional) = 57 % Maximal response obtained for each drug normalized to effect of carbachol in Muscarinic acetylcholine receptor M3 ChEMBL. 9651157
CCh (functional) = 60 % Maximal response obtained for each drug normalized to effect of carbachol in Muscarinic acetylcholine receptor M5 ChEMBL. 9651157
CCh (functional) = 65 % Maximal response obtained for each drug normalized to effect of carbachol in Muscarinic acetylcholine receptor M4 ChEMBL. 9651157
ED50 (functional) = 3.7 uM Stimulations of inositol phosphate(PI) accumulation in transfected CHO cells in Muscarinic acetylcholine receptor M1 values are the maximal response obtained from the compound tested at 100 uM normalized to the effect of carbachol. ChEMBL. 9651157
ED50 (functional) = 1078 uM Amplification of transfected NIH3T3 cells was measured in Muscarinic acetylcholine receptor M4 required to produce half maximal effect ChEMBL. 9651157
ED50 (functional) = 1535 uM Amplification of transfected NIH3T3 cells was measured in Muscarinic acetylcholine receptor M2 required to produce half maximal effect ChEMBL. 9651157
ED50 (functional) = 1605 uM Amplification of transfected NIH3T3 cells was measured in Muscarinic acetylcholine receptor M1 required to produce half maximal effect ChEMBL. 9651157
ED50 (functional) = 2590 uM Amplification of transfected NIH3T3 cells was measured in Muscarinic acetylcholine receptor M5 required to produce half maximal effect ChEMBL. 9651157
ED50 (functional) = 4568 uM Amplification of transfected NIH3T3 cells was measured in Muscarinic acetylcholine receptor M3 required to produce half maximal effect ChEMBL. 9651157
Stimulation (functional) = 1.9 % Stimulations of inositol phosphate(PI) accumulation in transfected CHO cells in Muscarinic acetylcholine receptor M5 values are the maximal response obtained from the compound tested at 100 uM normalized to the effect of carbachol. ChEMBL. 9651157
Stimulation (functional) = 5.2 % Stimulations of inositol phosphate(PI) accumulation in transfected CHO cells in Muscarinic acetylcholine receptor M3 values are the maximal response obtained from the compound tested at 100 uM normalized to the effect of carbachol. ChEMBL. 9651157
Stimulation (functional) = 81.7 % Stimulations of inositol phosphate(PI) accumulation in transfected CHO cells in Muscarinic acetylcholine receptor M1 values are the maximal response obtained from the compound tested at 100 uM normalized to the effect of carbachol. ChEMBL. 9651157

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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