Detailed information for compound 1599479

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 488.456 | Formula: C24H31Cl2N7
  • H donors: 3 H acceptors: 3 LogP: 6.49 Rotable bonds: 13
    Rule of 5 violations (Lipinski): 1
  • SMILES: CN(CCCNc1nc(NCCc2ccc(cc2)Cl)nc(n1)NCCc1ccc(cc1)Cl)C
  • InChi: 1S/C24H31Cl2N7/c1-33(2)17-3-14-27-22-30-23(28-15-12-18-4-8-20(25)9-5-18)32-24(31-22)29-16-13-19-6-10-21(26)11-7-19/h4-11H,3,12-17H2,1-2H3,(H3,27,28,29,30,31,32)
  • InChiKey: YCUAFUMMCRCDTQ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Rattus norvegicus Vanilloid receptor Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma brucei unspecified product 0.0036 0.0184 0.0906
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0247 0.0247
Mycobacterium tuberculosis Conserved hypothetical protein 0.0157 0.1023 0.0985
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0204 0.1354 0.1349
Mycobacterium tuberculosis Probable hydrolase 0.0035 0.018 0.0138
Schistosoma mansoni phd/f-box containing protein 0.0015 0.0041 0.0041
Plasmodium vivax diacylglycerol kinase, putative 0.0056 0.0325 0.2689
Entamoeba histolytica hypothetical protein 0.0107 0.068 0.0666
Trypanosoma cruzi diacylglycerol kinase, putative 0.0056 0.0325 0.1613
Brugia malayi Latrophilin receptor protein 2 0.0204 0.1354 0.3061
Brugia malayi ImpB/MucB/SamB family protein 0.0077 0.0471 0.1065
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0022 0.0086 0.008
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0098 0.0082
Loa Loa (eye worm) hypothetical protein 0.0024 0.0098 0.0092
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.0043 0.0365
Loa Loa (eye worm) 6-phosphofructokinase 0.0105 0.0664 0.0659
Echinococcus granulosus neuropeptide receptor A26 0.0447 0.3044 0.3039
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0061 0.0361 0.1793
Loa Loa (eye worm) hypothetical protein 0.005 0.0283 0.0277
Trichomonas vaginalis sphingosine kinase, putative 0.0056 0.0325 0.1781
Echinococcus granulosus bloom syndrome protein 0.0045 0.0244 0.0238
Echinococcus granulosus histone acetyltransferase KAT2B 0.0136 0.0881 0.0875
Toxoplasma gondii histone lysine methyltransferase SET1 0.0166 0.1092 0.9936
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0018 0.0061 0.0535
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.005 0.005
Trypanosoma brucei Sphingosine kinase 0.0056 0.0325 0.1613
Trichomonas vaginalis esterase, putative 0.0035 0.018 0.0973
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.013 0.0124
Trypanosoma brucei DNA polymerase eta, putative 0.0077 0.0471 0.2343
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0052 0.0297 0.0297
Loa Loa (eye worm) hypothetical protein 0.0012 0.002 0.0014
Mycobacterium tuberculosis Probable esterase LipL 0.0035 0.018 0.0138
Echinococcus multilocularis dna polymerase eta 0.0077 0.0471 0.0465
Echinococcus granulosus Diacylglycerol kinase theta 0.0056 0.0325 0.0319
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0167 0.1099 0.6077
Schistosoma mansoni mixed-lineage leukemia protein mll 0.018 0.1185 0.1185
Brugia malayi photoreceptor-specific nuclear receptor 0.002 0.0071 0.0161
Entamoeba histolytica phosphoglycerate kinase, putative 0.0167 0.1099 0.1085
Plasmodium falciparum histone acetyltransferase GCN5 0.0038 0.0196 0.1666
Echinococcus multilocularis sphingosine kinase 1 0.1446 1 1
Brugia malayi Nuclear hormone receptor family member nhr-49 0.002 0.0071 0.0161
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0024 0.0098 0.0055
Trypanosoma cruzi ISWI complex protein 0.0015 0.0038 0.0176
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0167 0.1099 0.5483
Trypanosoma brucei diacylglycerol kinase, putative 0.0056 0.0325 0.1613
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0035 0.0179 0.0173
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.0025 0.0107 0.0065
Brugia malayi Phosphoglycerate kinase 0.0167 0.1099 0.2484
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0019 0.0062 0.0541
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0035 0.018 0.0138
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0047 0.026 0.1654
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0024 0.0098 0.0052
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0018 0.0061 0.0424
Trypanosoma brucei DNA polymerase kappa, putative 0.0078 0.0479 0.2382
Mycobacterium ulcerans 6-phosphofructokinase 0.0105 0.0664 0.0621
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0059 0.0342 0.0301
Loa Loa (eye worm) hypothetical protein 0.0056 0.0325 0.0319
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0027 0.0121 0.0115
Loa Loa (eye worm) hypothetical protein 0.0018 0.0061 0.0055
Leishmania major sphingosine kinase A, B, putative 0.0056 0.0325 0.1613
Leishmania major hypothetical protein, conserved 0.0056 0.0325 0.1613
Schistosoma mansoni myelin transcription factor 1 myt1 0.0053 0.0305 0.0305
Loa Loa (eye worm) hypothetical protein 0.0038 0.0196 0.019
Echinococcus granulosus acylglycerol kinase mitochondrial 0.0056 0.0325 0.0319
Trypanosoma brucei DNA damage repair protein, putative 0.0016 0.0046 0.0216
Echinococcus granulosus phosphoglycerate kinase 1 0.0167 0.1099 0.1094
Plasmodium falciparum diacylglycerol kinase, putative 0.0056 0.0325 0.2859
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0035 0.018 0.0138
Loa Loa (eye worm) hypothetical protein 0.0018 0.0056 0.005
Onchocerca volvulus 0.0047 0.026 0.1654
Brugia malayi hypothetical protein 0.0107 0.068 0.1538
Brugia malayi Nuclear hormone receptor-like 1 0.002 0.0071 0.0161
Mycobacterium ulcerans phosphoglycerate kinase 0.0167 0.1099 0.1058
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0141 0.0912 0.4549
Mycobacterium ulcerans hypothetical protein 0.0024 0.0098 0.0052
Leishmania major diacylglycerol kinase, putative 0.0056 0.0325 0.1613
Plasmodium vivax diacylglycerol kinase, putative 0.0056 0.0325 0.2689
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0028 0.0131 0.0701
Echinococcus multilocularis Diacylglycerol kinase zeta 0.0056 0.0325 0.0319
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.001 0.0006 0.0006
Trypanosoma brucei phosphoglycerate kinase, putative 0.0061 0.0361 0.1793
Onchocerca volvulus 0.0035 0.018 0.1145
Brugia malayi latrophilin 2 splice variant baaae 0.0441 0.3004 0.6788
Schistosoma mansoni cpg binding protein 0.0084 0.052 0.052
Brugia malayi hypothetical protein 0.001 0.0006 0.0014
Echinococcus granulosus GPCR family 2 0.0204 0.1354 0.1349
Schistosoma mansoni glutaminase 0.0269 0.1806 0.1806
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0142 0.0924 0.0919
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0043 0.02
Leishmania major phosphoglycerate kinase C, glycosomal 0.0167 0.1099 0.5483
Trichomonas vaginalis helicase, putative 0.0019 0.0066 0.0342
Echinococcus multilocularis SAM and MBT domain containing protein 0.0047 0.026 0.0254
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0062 0.0296
Trypanosoma brucei DNA polymerase IV, putative 0.0078 0.0479 0.2382
Entamoeba histolytica hypothetical protein 0.0107 0.068 0.0666
Plasmodium falciparum DNA repair protein REV1, putative 0.0016 0.0046 0.0282
Trypanosoma cruzi DNA polymerase kappa, putative 0.0078 0.0479 0.2382
Loa Loa (eye worm) jmjC domain-containing protein 0.0015 0.0041 0.0034
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0024 0.0098 0.0052
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.002 0.0071 0.0065
Echinococcus granulosus cpg binding protein 0.0091 0.0566 0.0561
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0043 0.0037
Loa Loa (eye worm) eye-specific diacylglycerol kinase 0.0056 0.0325 0.0319
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0228 0.1127
Echinococcus multilocularis neuropeptide receptor A26 0.0447 0.3044 0.3039
Trichomonas vaginalis DNA helicase recq, putative 0.0024 0.0099 0.0525
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0024 0.0098 0.0098
Loa Loa (eye worm) hypothetical protein 0.0035 0.018 0.0174
Trichomonas vaginalis phosphofructokinase, putative 0.0105 0.0664 0.3663
Mycobacterium tuberculosis Bacterioferritin BfrB 0.0025 0.0107 0.0065
Trypanosoma cruzi DNA polymerase eta, putative 0.0041 0.022 0.1089
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0247 0.0247
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.018 0.018
Entamoeba histolytica acyl-coA synthetase, putative 0.0024 0.0098 0.0082
Trypanosoma brucei DNA polymerase kappa, putative 0.0078 0.0479 0.2382
Mycobacterium ulcerans diacylglycerol kinase 0.0056 0.0325 0.0281
Trichomonas vaginalis phosphofructokinase, putative 0.0028 0.0131 0.0701
Echinococcus granulosus dnaJ subfamily B 0.12 0.8288 0.8287
Echinococcus multilocularis ferritin 0.0025 0.0107 0.0101
Brugia malayi beta-lactamase 0.0035 0.018 0.0406
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0016 0.0043 0.0043
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0066 0.0342
Loa Loa (eye worm) hypothetical protein 0.0015 0.0041 0.0034
Toxoplasma gondii hypothetical protein 0.0048 0.0267 0.2409
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0022 0.0086 0.008
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0032 0.0157 0.077
Loa Loa (eye worm) isocitrate dehydrogenase 0.0016 0.0043 0.0037
Leishmania major hypothetical protein, conserved 0.0015 0.0038 0.0176
Schistosoma mansoni nuclear hormone receptor 0.002 0.0071 0.0071
Wolbachia endosymbiont of Brugia malayi bacterioferritin/cytochrome b1 0.0025 0.0107 0.0951
Echinococcus multilocularis polycomb protein SCMH1 0.0047 0.026 0.0254
Schistosoma mansoni jumonji domain containing protein 0.0058 0.0336 0.0336
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0042 0.0224 0.1107
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.002 0.0071 0.0065
Echinococcus granulosus lysine specific demethylase 5A 0.0065 0.0382 0.0377
Echinococcus multilocularis lysine specific demethylase 5A 0.0058 0.0336 0.033
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.002 0.0071 0.0065
Plasmodium falciparum JmjC domain-containing protein, putative 0.0015 0.0041 0.0232
Mycobacterium leprae conserved hypothetical protein 0.0035 0.018 0.0821
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0053 0.0305 0.0299
Mycobacterium ulcerans lipase LipD 0.0035 0.018 0.0134
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0018 0.0061 0.0139
Echinococcus granulosus expressed protein 0.0025 0.0107 0.0101
Echinococcus granulosus ecdysone induced protein 78C 0.002 0.0071 0.0065
Echinococcus granulosus beta LACTamase domain containing family member 0.0035 0.018 0.0174
Brugia malayi Bloom's syndrome protein homolog 0.0045 0.0244 0.0551
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0105 0.0664 0.3309
Loa Loa (eye worm) hypothetical protein 0.0645 0.4425 0.4421
Loa Loa (eye worm) hypothetical protein 0.002 0.0071 0.0065
Plasmodium vivax phosphoglycerate kinase, putative 0.0167 0.1099 1
Loa Loa (eye worm) acetyltransferase 0.0142 0.0924 0.0919
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0062 0.0203
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0015 0.0041 0.0189
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0028 0.0131 0.0716
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0032 0.0157 0.077
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0049 0.0007
Loa Loa (eye worm) phosphofructokinase 0.0105 0.0664 0.0659
Schistosoma mansoni hypothetical protein 0.0056 0.0325 0.0325
Brugia malayi Nuclear hormone receptor-like 1 0.001 0.0006 0.0014
Echinococcus multilocularis GPCR, family 2 0.0204 0.1354 0.1349
Schistosoma mansoni ferritin light chain 0.0025 0.0107 0.0107
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.018 0.0886
Trichomonas vaginalis conserved hypothetical protein 0.0056 0.0325 0.1781
Brugia malayi mbt repeat family protein 0.0047 0.026 0.0587
Echinococcus granulosus jumonji domain containing 1A 0.0015 0.0041 0.0034
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.001 0.0004 0.00000000029352
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0028 0.0131 0.0662
Echinococcus granulosus FTZ F1 alpha 0.002 0.0071 0.0065
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0024 0.0098 0.0098
Treponema pallidum phosphoglycerate kinase 0.0167 0.1099 1
Loa Loa (eye worm) hypothetical protein 0.0044 0.0236 0.023
Brugia malayi acetyltransferase, GNAT family protein 0.0142 0.0924 0.2089
Trichomonas vaginalis phosphofructokinase, putative 0.0105 0.0664 0.3663
Loa Loa (eye worm) latrophilin receptor protein 2 0.0204 0.1354 0.1349
Loa Loa (eye worm) hypothetical protein 0.0018 0.0056 0.005
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0028 0.0131 0.1167
Schistosoma mansoni myst-related protein 0.0012 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0018 0.0056 0.005
Loa Loa (eye worm) hypothetical protein 0.002 0.0071 0.0065
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0247 0.0241
Loa Loa (eye worm) hypothetical protein 0.0204 0.1354 0.1349
Brugia malayi Pre-SET motif family protein 0.0207 0.1372 0.31
Entamoeba histolytica recQ family helicase, putative 0.0024 0.0099 0.0084
Loa Loa (eye worm) hypothetical protein 0.0018 0.0056 0.005
Brugia malayi Ceramide kinase 0.0056 0.0325 0.0735
Toxoplasma gondii diacylglycerol kinase, putative 0.0056 0.0325 0.2942
Onchocerca volvulus 0.002 0.0071 0.0453
Schistosoma mansoni DNA helicase recq1 0.0018 0.0061 0.0061
Loa Loa (eye worm) jmjC domain-containing protein 0.0065 0.0382 0.0377
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.002 0.0071 0.0065
Loa Loa (eye worm) glutaminase 0.0269 0.1806 0.1801
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0066 0.0342
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.018 0.0973
Toxoplasma gondii t-complex protein beta subunit 0.0024 0.0098 0.0867
Echinococcus granulosus ferritin 0.0025 0.0107 0.0101
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0645 0.4425 1
Onchocerca volvulus 0.0011 0.0007 0.0047
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0028 0.0131 0.1063
Trichomonas vaginalis phosphofructokinase, putative 0.0028 0.0131 0.0701
Plasmodium vivax 6-phosphofructokinase, putative 0.0028 0.0131 0.0851
Trypanosoma cruzi Sphingosine kinase 0.0056 0.0325 0.1613
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.018 0.0973
Loa Loa (eye worm) hypothetical protein 0.0024 0.0098 0.0092
Brugia malayi F/Y-rich N-terminus family protein 0.0029 0.0133 0.03
Loa Loa (eye worm) hypothetical protein 0.0048 0.0267 0.0261
Leishmania major DNA polymerase kappa, putative 0.0016 0.0046 0.0216
Echinococcus multilocularis phd:f box containing protein 0.0015 0.0041 0.0034
Brugia malayi Bromodomain containing protein 0.0041 0.0219 0.0496
Brugia malayi jmjC domain containing protein 0.0058 0.0336 0.0759
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0044 0.0236 0.1286
Trichomonas vaginalis DNA helicase recq1, putative 0.0045 0.0244 0.1329
Brugia malayi diacylglycerol kinase 0.0056 0.0325 0.0735
Schistosoma mansoni terminal deoxycytidyl transferase 0.0052 0.0297 0.0297
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0032 0.0157 0.0141
Loa Loa (eye worm) hypothetical protein 0.0024 0.0098 0.0092
Leishmania major DNA polymerase kappa, putative 0.0059 0.0342 0.1696
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0022 0.0086 0.0086
Schistosoma mansoni transcription factor LCR-F1 0.0107 0.068 0.068
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.002 0.0071 0.0065
Brugia malayi Steroid receptor seven-up type 2 0.002 0.0071 0.0161
Trypanosoma cruzi DNA polymerase eta, putative 0.0077 0.0471 0.2343
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0297 0.2002 1
Echinococcus granulosus dna polymerase eta 0.0077 0.0471 0.0465
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0024 0.0099 0.0482
Brugia malayi diacylglycerol kinase 0.0056 0.0325 0.0735
Mycobacterium leprae Probable lipase LipE 0.0035 0.018 0.0821
Trichomonas vaginalis bmru protein, putative 0.0056 0.0325 0.1781
Trypanosoma cruzi hypothetical protein, conserved 0.0056 0.0325 0.1613
Brugia malayi nuclear hormone receptor 0.002 0.0071 0.0161
Brugia malayi jmjC domain containing protein 0.0015 0.0041 0.0092
Leishmania major hypothetical protein, conserved 0.0015 0.0041 0.0189
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0066 0.0342
Trypanosoma brucei DNA polymerase kappa, putative 0.0078 0.0479 0.2382
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0098 0.0082
Echinococcus multilocularis neuropeptide s receptor 0.0447 0.3044 0.3039
Mycobacterium ulcerans hypothetical protein 0.0035 0.018 0.0134
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0042 0.0224 0.1107
Echinococcus multilocularis expressed protein 0.0025 0.0107 0.0101
Brugia malayi nuclear receptor NHR-88 0.002 0.0071 0.0161
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0018 0.0061 0.0535
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0207 0.1372 0.1367
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0062 0.0319
Mycobacterium tuberculosis Conserved protein 0.1446 1 1
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0052 0.0297 0.0291
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0061 0.0361 0.1793
Trypanosoma brucei Diacylglycerol kinase catalytic domain containing protein, putative 0.0056 0.0325 0.1613
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0024 0.0099 0.0482
Schistosoma mansoni DNA helicase recq5 0.0018 0.0061 0.0061
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0033 0.0162 0.0156
Echinococcus granulosus transcription factor Dp 1 0.0038 0.0195 0.0189
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0062 0.0056
Schistosoma mansoni hypothetical protein 0.0015 0.0038 0.0038
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0052 0.0297 0.0291
Entamoeba histolytica hypothetical protein 0.0107 0.068 0.0666
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0066 0.0342
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0027 0.0121 0.0121
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0035 0.018 0.0174
Trichomonas vaginalis diacylglycerol kinase, zeta, iota, putative 0.0056 0.0325 0.1781
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.002 0.0071 0.0065
Loa Loa (eye worm) hypothetical protein 0.0035 0.018 0.0174
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0018 0.0061 0.0139
Entamoeba histolytica hypothetical protein, conserved 0.1446 1 1
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0031 0.015 0.0144
Brugia malayi phosphofructokinase 0.0105 0.0664 0.1501
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0247 0.0241
Echinococcus granulosus zinc finger protein 0.0027 0.0125 0.0119
Trypanosoma brucei ISWI complex protein 0.0015 0.0038 0.0176
Plasmodium vivax SET domain protein, putative 0.0031 0.015 0.1038
Loa Loa (eye worm) hypothetical protein 0.002 0.0071 0.0065
Schistosoma mansoni coup transcription factor 0.002 0.0071 0.0071
Brugia malayi ImpB/MucB/SamB family protein 0.0052 0.0297 0.0671
Giardia lamblia DINP protein human, muc B family 0.0059 0.0342 0.281
Trypanosoma brucei DNA polymerase IV, putative 0.0078 0.0479 0.2382
Trichomonas vaginalis diacylglycerol kinase, putative 0.0056 0.0325 0.1781
Trichomonas vaginalis chaperonin, putative 0.0024 0.0098 0.0518
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0065 0.0385 0.1914
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0062 0.0296
Loa Loa (eye worm) CXXC zinc finger family protein 0.0084 0.052 0.0514
Mycobacterium tuberculosis Probable lipase LipD 0.0035 0.018 0.0138
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0105 0.0664 0.0624
Brugia malayi hypothetical protein 0.0056 0.0325 0.0735
Schistosoma mansoni phosphoglycerate kinase 0.0167 0.1099 0.1099
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0024 0.0099 0.0482
Loa Loa (eye worm) hypothetical protein 0.1446 1 1
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0162 0.0874
Trypanosoma brucei DNA polymerase kappa, putative 0.0078 0.0479 0.2382
Giardia lamblia TCP-1 chaperonin subunit beta 0.0024 0.0098 0.0492
Entamoeba histolytica hypothetical protein 0.0107 0.068 0.0666
Trypanosoma cruzi diacylglycerol kinase, putative 0.0056 0.0325 0.1613
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0098 0.0052
Toxoplasma gondii ABC1 family protein 0.0035 0.018 0.1615
Leishmania major mitochondrial DNA polymerase beta 0.0297 0.2002 1
Echinococcus granulosus 6 phosphofructokinase 0.0105 0.0664 0.0659
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0019 0.0062 0.0047
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.002 0.0071 0.0071
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0041 0.022 0.1986
Brugia malayi jmjC domain containing protein 0.0015 0.0041 0.0092
Trichomonas vaginalis phosphofructokinase, putative 0.0028 0.0131 0.0701
Schistosoma mansoni apoferritin-2 0.0025 0.0107 0.0107
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0066 0.0342
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0204 0.1354 0.1349
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0067 0.0399 0.0394
Mycobacterium tuberculosis Conserved hypothetical protein 0.0052 0.0297 0.0255
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0016 0.0043 0.0037
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0058 0.0336 0.033
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0013 0.0025 0.0025
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0204 0.1354 0.3061
Schistosoma mansoni hypothetical protein 0.0169 0.1108 0.1108
Leishmania major phosphoglycerate kinase B, cytosolic 0.0167 0.1099 0.5483
Loa Loa (eye worm) mbt repeat family protein 0.0047 0.026 0.0254
Brugia malayi ecdysteroid receptor 0.002 0.0071 0.0161
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0141 0.0912 0.4549
Echinococcus multilocularis thyroid hormone receptor alpha 0.002 0.0071 0.0065
Trichomonas vaginalis glutaminase, putative 0.0269 0.1806 1
Schistosoma mansoni protein phosphatase 2C 0.0015 0.0041 0.0041
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0015 0.0041 0.0345
Mycobacterium tuberculosis Conserved protein 0.0035 0.018 0.0138
Onchocerca volvulus 0.0031 0.015 0.0958
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0033 0.0162 0.0366
Trichomonas vaginalis phosphofructokinase, putative 0.0028 0.0131 0.0701
Schistosoma mansoni retinoid-x-receptor (RXR) 0.002 0.0071 0.0071
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0247 0.0241
Loa Loa (eye worm) hypothetical protein 0.002 0.0071 0.0065
Trichomonas vaginalis diacylglycerol kinase, zeta, iota, putative 0.0056 0.0325 0.1781
Echinococcus granulosus histone acetyltransferase MYST2 0.0053 0.0305 0.0299
Loa Loa (eye worm) hypothetical protein 0.0056 0.0325 0.0319
Echinococcus granulosus fetal alzheimer antigen falz 0.0027 0.0121 0.0115
Leishmania major hypothetical protein, conserved 0.0056 0.0325 0.1613
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0071 0.0161
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0071 0.0161
Leishmania major DNA damage repair protein, putative 0.0016 0.0046 0.0216
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0015 0.0041 0.0189
Schistosoma mansoni zinc finger protein 0.0027 0.0125 0.0125
Schistosoma mansoni hypothetical protein 0.002 0.0074 0.0074
Brugia malayi hypothetical protein 0.001 0.0006 0.0014
Trypanosoma brucei DNA polymerase kappa, putative 0.0078 0.0479 0.2382
Trypanosoma brucei hypothetical protein, conserved 0.0016 0.0046 0.0216
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0019 0.0062 0.0016
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.018 0.018
Schistosoma mansoni RAR-like nuclear receptor 0.002 0.0071 0.0071
Chlamydia trachomatis phosphoglycerate kinase 0.0167 0.1099 1
Trypanosoma cruzi diacylglycerol kinase-like protein, putative 0.0056 0.0325 0.1613
Entamoeba histolytica acetyltransferase, GNAT family 0.0038 0.0196 0.0181
Echinococcus multilocularis transcription factor Dp 1 0.0038 0.0195 0.0189
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0645 0.4425 0.4421
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0062 0.0056
Trypanosoma brucei hypothetical protein, conserved 0.0016 0.0046 0.0216
Schistosoma mansoni diacylglycerol kinase zeta iota 0.0056 0.0325 0.0325
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0016 0.0043 0.02
Schistosoma mansoni hypothetical protein 0.0107 0.068 0.068
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0062 0.0296
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0031 0.015 0.1348
Brugia malayi MH2 domain containing protein 0.0119 0.0761 0.172
Echinococcus granulosus mixed lineage leukemia protein mll 0.0022 0.0086 0.008
Schistosoma mansoni ferritin 0.0025 0.0107 0.0107
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0065 0.0385 0.038
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0098 0.0052
Loa Loa (eye worm) MBCTL1 0.0053 0.0305 0.0299
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0247 0.0241
Echinococcus granulosus JmjC domain containing protein 4 0.0015 0.0041 0.0034
Mycobacterium ulcerans glutaminase 0.0269 0.1806 0.1768
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0024 0.0098 0.0052
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0042 0.0224 0.1107
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0019 0.0062 0.0152
Onchocerca volvulus 0.0035 0.018 0.1145
Echinococcus multilocularis intestinal type alkaline phosphatase 0.016 0.1047 0.1042
Loa Loa (eye worm) hypothetical protein 0.002 0.0071 0.0065
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0098 0.0052
Schistosoma mansoni ferritin 0.0025 0.0107 0.0107
Trichomonas vaginalis phosphofructokinase, putative 0.0028 0.0131 0.0701
Schistosoma mansoni jumonji/arid domain-containing protein 0.0065 0.0382 0.0382
Plasmodium falciparum T-complex protein 1 subunit beta 0.0024 0.0098 0.076
Trypanosoma brucei hypothetical protein, conserved 0.0035 0.018 0.0886
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0039 0.0206 0.1759
Schistosoma mansoni proteasome subunit alpha 6 (T01 family) 0.0056 0.0325 0.0325
Brugia malayi Isocitrate dehydrogenase 0.0016 0.0043 0.0096
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0042 0.0224 0.1107
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0071 0.0161
Echinococcus granulosus chaperonin containing TCP1 subunit 2 beta 0.0024 0.0098 0.0092
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0044 0.0236 0.1847
Trypanosoma cruzi DNA polymerase kappa, putative 0.0078 0.0479 0.2382
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0018 0.0061 0.0055
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0015 0.0041 0.0345
Schistosoma mansoni jumonji/arid domain-containing protein 0.0065 0.0382 0.0382
Plasmodium vivax 6-phosphofructokinase, putative 0.0028 0.0131 0.0851
Schistosoma mansoni ap endonuclease 0.0019 0.0062 0.0062
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0107 0.068 0.0675
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0066 0.0342
Loa Loa (eye worm) jmjC domain-containing protein 0.0015 0.0041 0.0034
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0053 0.0305 0.0299
Onchocerca volvulus 0.0035 0.018 0.1145
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0016 0.0043 0.02
Trypanosoma cruzi DNA polymerase kappa, putative 0.0078 0.0479 0.2382
Echinococcus granulosus alkaline phosphatase intestinal gene 2 0.016 0.1047 0.1042
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0141 0.0912 0.4549
Trypanosoma cruzi 3-phosphoglycerate kinase, glycosomal 0.0061 0.0361 0.1793
Schistosoma mansoni hypothetical protein 0.0204 0.1354 0.1354
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0098 0.022
Loa Loa (eye worm) glutaminase 2 0.0269 0.1806 0.1801
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0016 0.0043 0.0252
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0204 0.1354 0.1349
Brugia malayi nuclear receptor RXR 0.001 0.0006 0.0014
Trypanosoma cruzi Diacylglycerol kinase catalytic domain containing protein, putative 0.0056 0.0325 0.1613
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0065 0.0385 0.1914
Toxoplasma gondii diacylglycerol kinase accessory domain (presumed) domain-containing protein 0.0056 0.0325 0.2942
Toxoplasma gondii peptidylprolyl isomerase 0.0032 0.0157 0.1403
Loa Loa (eye worm) transcription factor SMAD2 0.0119 0.0761 0.0755
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0105 0.0664 0.5807
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0062 0.014
Trichomonas vaginalis ferritin, putative 0.0025 0.0107 0.0569
Schistosoma mansoni steroid hormone receptor ad4bp 0.002 0.0071 0.0071
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.018 0.0973
Echinococcus granulosus intestinal type alkaline phosphatase 0.016 0.1047 0.1042
Schistosoma mansoni Tr4/Tr2 (homologue) 0.002 0.0071 0.0071
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0098 0.0474
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0018 0.0061 0.0055
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0071 0.0161
Trypanosoma brucei DNA damage repair protein, putative 0.0016 0.0046 0.0216
Brugia malayi mbt repeat family protein 0.0047 0.026 0.0587
Loa Loa (eye worm) hypothetical protein 0.007 0.0418 0.0412
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.0062 0.0019
Schistosoma mansoni apoferritin-2 0.0025 0.0107 0.0107
Schistosoma mansoni bromodomain containing protein 0.0012 0.002 0.002
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0066 0.0342
Mycobacterium tuberculosis Diacylglycerol kinase 0.0056 0.0325 0.0284
Echinococcus multilocularis zinc finger protein 0.0027 0.0125 0.0119
Plasmodium falciparum phosphoglycerate kinase 0.0167 0.1099 1
Schistosoma mansoni diacylglycerol kinase theta 0.0056 0.0325 0.0325
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0015 0.0041 0.0041
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0071 0.0065
Schistosoma mansoni hypothetical protein 0.0204 0.1354 0.1354
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0049 0.0007
Schistosoma mansoni zinc finger protein 0.0015 0.0038 0.0038
Trypanosoma cruzi ISWI complex protein 0.0015 0.0038 0.0176
Leishmania major DNA polymerase eta, putative 0.0041 0.022 0.1089
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.002 0.0071 0.0071
Echinococcus granulosus Diacylglycerol kinase zeta 0.0056 0.0325 0.0319
Loa Loa (eye worm) hypothetical protein 0.002 0.0071 0.0065
Plasmodium vivax hypothetical protein, conserved 0.0035 0.018 0.1316
Trichomonas vaginalis phosphofructokinase, putative 0.0105 0.0664 0.3663
Schistosoma mansoni retinoic acid receptor RXR 0.002 0.0071 0.0071
Mycobacterium ulcerans esterase/lipase LipP 0.0035 0.018 0.0134
Brugia malayi polk-prov protein 0.0042 0.0228 0.0516
Plasmodium vivax DNA repair protein REV1, putative 0.0016 0.0046 0.0051
Schistosoma mansoni ferritin 0.0025 0.0107 0.0107
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.003 0.0143 0.097
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0066 0.0342
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0035 0.018 0.0134
Loa Loa (eye worm) hypothetical protein 0.0053 0.0305 0.0299
Trypanosoma brucei phosphoglycerate kinase 0.0061 0.0361 0.1793
Mycobacterium ulcerans hypothetical protein 0.0157 0.1023 0.0982
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0071 0.0065
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0045 0.0247 0.0241
Schistosoma mansoni blooms syndrome DNA helicase 0.0035 0.0178 0.0178
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0062 0.043
Schistosoma mansoni hypothetical protein 0.0204 0.1354 0.1354
Brugia malayi Nuclear hormone receptor family member nhr-41 0.002 0.0071 0.0161
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0024 0.0098 0.0055
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0053 0.0305 0.0689
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0167 0.1099 0.5483
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0035 0.018 0.0138
Echinococcus granulosus intestinal type alkaline phosphatase 1 0.016 0.1047 0.1042
Echinococcus granulosus histone acetyltransferase KAT2B 0.0044 0.0236 0.023
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0044 0.0236 0.2128
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0018 0.0061 0.0055
Trypanosoma brucei T-complex protein 1, beta subunit, putative 0.0024 0.0098 0.0476
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0062 0.0296
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0019 0.0066 0.0342
Trichomonas vaginalis rotamase, putative 0.0032 0.0157 0.0844
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.002 0.0071 0.0071
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0048 0.0267 0.0267
Loa Loa (eye worm) hypothetical protein 0.002 0.0071 0.0065
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0016 0.0043 0.002
Loa Loa (eye worm) hypothetical protein 0.0035 0.018 0.0174
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0023 0.0091 0.0807
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0018 0.0056 0.001
Leishmania major hypothetical protein, conserved 0.0035 0.018 0.0886
Schistosoma mansoni phosphatidylserine receptor 0.0015 0.0041 0.0041
Echinococcus granulosus dna polymerase kappa 0.0078 0.0479 0.0473
Trypanosoma cruzi hypothetical protein, conserved 0.0016 0.0046 0.0216
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0065 0.0385 0.0385
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0066 0.0342
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0066 0.0342
Loa Loa (eye worm) hypothetical protein 0.0035 0.018 0.0174
Echinococcus multilocularis 6 phosphofructokinase 0.0105 0.0664 0.0659
Echinococcus granulosus geminin 0.0169 0.1108 0.1103
Mycobacterium ulcerans hypothetical protein 0.1446 1 1
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0019 0.0066 0.0342
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0015 0.0041 0.0189
Entamoeba histolytica diacylglycerol kinase, putative 0.0056 0.0325 0.031
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0142 0.0924 0.0924
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.002 0.0071 0.0065
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.002 0.0071 0.0065
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0065 0.0385 0.038
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0065 0.0385 0.0871
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0043 0.02
Giardia lamblia Phosphoglycerate kinase 0.0167 0.1099 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.015 0.015
Schistosoma mansoni phosphoglycerate kinase 0.0167 0.1099 0.1099
Schistosoma mansoni bromodomain containing protein 0.007 0.0424 0.0424
Trypanosoma cruzi T-complex protein 1, beta subunit, putative 0.0024 0.0098 0.0476
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.002 0.0071 0.0065
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0045 0.0247 0.0558
Toxoplasma gondii 6-phosphofructokinase 0.0028 0.0131 0.1167
Entamoeba histolytica diacylglycerol kinase, putative 0.0056 0.0325 0.031
Onchocerca volvulus 0.0084 0.052 0.3309
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0066 0.0342
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0061 0.0361 0.1793
Loa Loa (eye worm) hypothetical protein 0.0136 0.0878 0.0872
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0028 0.0131 0.1063
Mycobacterium ulcerans beta-lactamase 0.0035 0.018 0.0134
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0018 0.0061 0.0055
Schistosoma mansoni retinoid-x-receptor (RXR) 0.001 0.0006 0.0006
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0035 0.0179 0.0173
Loa Loa (eye worm) hypothetical protein 0.0015 0.0041 0.0034
Echinococcus granulosus expressed protein 0.0033 0.0162 0.0156
Mycobacterium ulcerans DNA polymerase IV 0.0078 0.0479 0.0435
Echinococcus granulosus polycomb protein SCMH1 0.0047 0.026 0.0254
Trypanosoma cruzi diacylglycerol kinase-like protein, putative 0.0056 0.0325 0.1613
Toxoplasma gondii phosphofructokinase PFKII 0.0028 0.0131 0.1167
Entamoeba histolytica deoxycytidyl transferase, putative 0.0052 0.0297 0.0282
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0052 0.0297 0.0291
Echinococcus multilocularis histone acetyltransferase MYST2 0.0053 0.0305 0.0299
Leishmania major diacylglycerol kinase-like protein 0.0056 0.0325 0.1613
Echinococcus multilocularis bloom syndrome protein 0.0045 0.0244 0.0238
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0049 0.0007
Loa Loa (eye worm) hypothetical protein 0.0035 0.018 0.0174
Echinococcus granulosus ceramide kinase 0.0056 0.0325 0.0319
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.002 0.0071 0.0065
Schistosoma mansoni hypothetical protein 0.0083 0.0512 0.0512
Schistosoma mansoni sphingoid long chain base kinase 0.1446 1 1
Brugia malayi Eye-specific diacylglycerol kinase 0.0056 0.0325 0.0735
Mycobacterium tuberculosis Conserved protein 0.0035 0.018 0.0138
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.002 0.0071 0.0065
Brugia malayi CXXC zinc finger family protein 0.0084 0.052 0.1175
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0167 0.1099 0.6077
Echinococcus multilocularis chaperonin containing TCP1, subunit 2 (beta) 0.0024 0.0098 0.0092
Trypanosoma brucei DNA polymerase kappa, putative 0.0078 0.0479 0.2382
Loa Loa (eye worm) hypothetical protein 0.002 0.0071 0.0065
Schistosoma mansoni hypothetical protein 0.0441 0.3004 0.3004
Loa Loa (eye worm) diacylglycerol kinase 2 0.0056 0.0325 0.0319
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.002 0.0071 0.0065
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0022 0.0087 0.0081
Schistosoma mansoni ap endonuclease 0.0019 0.0062 0.0062
Trichomonas vaginalis rotamase, putative 0.0033 0.0162 0.0874
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.0229 0.1132
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0028 0.0131 0.0115
Loa Loa (eye worm) hypothetical protein 0.0077 0.0471 0.0465
Brugia malayi steroid hormone receptor 0.002 0.0071 0.0161
Echinococcus multilocularis alkaline phosphatase 0.016 0.1047 0.1042
Echinococcus granulosus histone lysine methyltransferase setb 0.0048 0.0267 0.0261
Brugia malayi Calcitonin receptor-like protein seb-1 0.0645 0.4425 1
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0105 0.0664 0.5658
Mycobacterium ulcerans DNA polymerase IV 0.0078 0.0479 0.0435
Loa Loa (eye worm) T-complex protein 1 0.0024 0.0098 0.0092
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0047 0.026 0.026
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0016 0.0043 0.0037
Trypanosoma brucei unspecified product 0.0036 0.0184 0.0906
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0078 0.0479 0.2634
Brugia malayi jmjC domain containing protein 0.0015 0.0041 0.0092
Schistosoma mansoni ferritin 0.0025 0.0107 0.0107
Brugia malayi PHD-finger family protein 0.0033 0.0161 0.0364
Schistosoma mansoni alkaline phosphatase 0.016 0.1047 0.1047
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0247 0.0247
Onchocerca volvulus Protein ultraspiracle homolog 0.002 0.0071 0.0453
Brugia malayi beta-lactamase family protein 0.0035 0.018 0.0406
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0066 0.0342
Echinococcus granulosus neuropeptide s receptor 0.0447 0.3044 0.3039
Onchocerca volvulus 0.0056 0.0325 0.207
Loa Loa (eye worm) jmjC domain-containing protein 0.0015 0.0041 0.0034
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0228 0.1127
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0061 0.0361 0.1793
Brugia malayi beta-lactamase family protein 0.0035 0.018 0.0406
Toxoplasma gondii diacylglycerol kinase catalytic domain-containing protein 0.0056 0.0325 0.2942
Trichomonas vaginalis bromodomain-containing protein, putative 0.0044 0.0236 0.1286
Loa Loa (eye worm) 6-phosphofructokinase 0.0105 0.0664 0.0659
Entamoeba histolytica phosphofructokinase, putative 0.0105 0.0664 0.065
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0043 0.0037
Trypanosoma brucei DNA polymerase kappa, putative 0.0078 0.0479 0.2382
Leishmania major DNA polymerase eta, putative 0.0077 0.0471 0.2343
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0043 0.02
Brugia malayi Nuclear hormone receptor-like 1 0.001 0.0006 0.0014
Treponema pallidum bacterioferrin (TpF1) 0.0025 0.0107 0.0434
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.002 0.0071 0.0065
Schistosoma mansoni sex comb on midleg homolog 0.0047 0.026 0.026
Schistosoma mansoni hypothetical protein 0.12 0.8288 0.8288
Echinococcus granulosus retinoic acid receptor rxr beta a 0.002 0.0071 0.0065
Loa Loa (eye worm) hypothetical protein 0.0441 0.3004 0.2999
Brugia malayi T-complex protein 1, beta subunit 0.0024 0.0098 0.0221
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0062 0.0056
Loa Loa (eye worm) hypothetical protein 0.0042 0.0228 0.0222
Echinococcus multilocularis cpg binding protein 0.0091 0.0566 0.0561
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0065 0.0385 0.0371
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.002 0.0071 0.0453
Entamoeba histolytica diacylglycerol kinase, putative 0.0056 0.0325 0.031
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0018 0.0056 0.0013
Trypanosoma cruzi Sphingosine kinase 0.0056 0.0325 0.1613
Schistosoma mansoni 6-phosphofructokinase 0.0105 0.0664 0.0664
Plasmodium falciparum acyl-CoA synthetase 0.0018 0.0056 0.0374
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0022 0.0087 0.0081
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0065 0.0385 0.1914
Loa Loa (eye worm) ceramide kinase 0.0056 0.0325 0.0319
Echinococcus multilocularis intestinal type alkaline phosphatase 1 0.016 0.1047 0.1042
Trypanosoma brucei phosphoglycerate kinase 0.0167 0.1099 0.5483
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0189 0.1246 0.1241
Schistosoma mansoni thyroid hormone receptor 0.002 0.0071 0.0071
Entamoeba histolytica phosphofructokinase, putative 0.0105 0.0664 0.065
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0189 0.1246 0.1241
Schistosoma mansoni cpg binding protein 0.0091 0.0566 0.0566
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0098 0.022
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0066 0.0342
Echinococcus multilocularis ecdysone induced protein 78C 0.002 0.0071 0.0065
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0297 0.2002 1
Onchocerca volvulus Bile acid receptor homolog 0.002 0.0071 0.0453
Mycobacterium ulcerans bacterioferritin BfrA 0.0025 0.0107 0.0061
Mycobacterium leprae PROBABLE BACTERIOFERRITIN BFRA 0.0025 0.0107 0.0095
Loa Loa (eye worm) hypothetical protein 0.0167 0.1099 0.1094
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0016 0.0046 0.0395
Entamoeba histolytica phosphofructokinase, putative 0.0105 0.0664 0.065
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0035 0.018 0.0406
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.003 0.0141 0.1259
Loa Loa (eye worm) hypothetical protein 0.0018 0.0056 0.005
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0071 0.0065
Brugia malayi 6-phosphofructokinase 0.0105 0.0664 0.1501
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0071 0.0161
Schistosoma mansoni hypothetical protein 0.0169 0.1108 0.1108
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.0229 0.1132
Plasmodium vivax T-complex protein 1 subunit beta, putative 0.0024 0.0098 0.0541
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0059 0.0342 0.1696
Loa Loa (eye worm) hypothetical protein 0.0035 0.018 0.0174
Echinococcus multilocularis ceramide kinase 0.0056 0.0325 0.0319
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.005 0.005
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.0043 0.0365
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.018 0.0973
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.018 0.0973
Brugia malayi Nuclear hormone receptor family member nhr-40 0.002 0.0071 0.0161
Loa Loa (eye worm) hypothetical protein 0.0015 0.0041 0.0034
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.0229 0.1132
Trypanosoma cruzi hypothetical protein, conserved 0.0016 0.0046 0.0216
Schistosoma mansoni sphingosine kinase A B 0.1446 1 1
Brugia malayi Nuclear hormone receptor family member nhr-14 0.002 0.0071 0.0161
Loa Loa (eye worm) hypothetical protein 0.0056 0.0325 0.0319
Trichomonas vaginalis diacylglycerol kinase, putative 0.0056 0.0325 0.1781
Echinococcus multilocularis geminin 0.0169 0.1108 0.1103
Trichomonas vaginalis phosphofructokinase, putative 0.0028 0.0131 0.0701
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0062 0.0319
Echinococcus granulosus phd:f box containing protein 0.0015 0.0041 0.0034
Onchocerca volvulus Ceramide kinase 1 homolog 0.0056 0.0325 0.207
Brugia malayi T-complex protein 1, beta subunit 0.0024 0.0098 0.0221
Wolbachia endosymbiont of Brugia malayi phosphoglycerate kinase 0.0167 0.1099 1
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0226 0.1509 0.1473
Echinococcus multilocularis dna polymerase kappa 0.0078 0.0479 0.0473
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0024 0.0098 0.0098
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0028 0.0131 0.0716
Echinococcus multilocularis jumonji domain containing 1A 0.0015 0.0041 0.0034
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0204 0.1354 0.1349
Brugia malayi jmjC domain containing protein 0.0065 0.0382 0.0864
Mycobacterium leprae Probable phosphoglycerate kinase Pgk 0.0167 0.1099 1
Echinococcus multilocularis lysine specific demethylase 6a 0.0015 0.0041 0.0034
Plasmodium falciparum diacylglycerol kinase, putative 0.0056 0.0325 0.2859
Brugia malayi 6-phosphofructokinase 0.0105 0.0664 0.1501
Trichomonas vaginalis DNA polymerase eta, putative 0.0078 0.0479 0.2634
Leishmania major ATP-dependent phosphofructokinase 0.0105 0.0664 0.3309
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0044 0.0236 0.2128
Mycobacterium tuberculosis Probable phosphoglycerate kinase Pgk 0.0167 0.1099 0.1061
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0022 0.0086 0.008
Trypanosoma cruzi DNA polymerase kappa, putative 0.0078 0.0479 0.2382
Echinococcus multilocularis JmjC domain containing protein 4 0.0015 0.0041 0.0034
Toxoplasma gondii exonuclease III APE 0.0019 0.0062 0.0541
Trypanosoma brucei hypothetical protein, conserved 0.0056 0.0325 0.1613
Schistosoma mansoni hypothetical protein 0.0204 0.1354 0.1354
Echinococcus multilocularis expressed protein 0.0033 0.0162 0.0156
Loa Loa (eye worm) steroid hormone receptor 0.002 0.0071 0.0065
Echinococcus multilocularis acylglycerol kinase, mitochondrial 0.0056 0.0325 0.0319
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0297 0.2002 1
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0067 0.0399 0.0394
Plasmodium vivax acyl-CoA synthetase, putative 0.0018 0.0056 0.0146
Brugia malayi Nuclear hormone receptor family member nhr-1 0.002 0.0071 0.0161
Schistosoma mansoni ferritin light chain 0.0025 0.0107 0.0107
Schistosoma mansoni rotamase 0.0033 0.0162 0.0162
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0048 0.0267 0.0267
Schistosoma mansoni DNA polymerase IV / kappa 0.0016 0.0046 0.0046
Schistosoma mansoni DNA polymerase eta 0.0077 0.0471 0.0471
Loa Loa (eye worm) hypothetical protein 0.0047 0.026 0.0254
Schistosoma mansoni myst-related protein 0.0012 0.0015 0.0015
Trypanosoma cruzi DNA damage repair protein, putative 0.0016 0.0046 0.0216
Trichomonas vaginalis phosphofructokinase, putative 0.0105 0.0664 0.3663
Echinococcus granulosus SAM and MBT domain containing protein 0.0047 0.026 0.0254
Loa Loa (eye worm) RecQ helicase 0.0045 0.0244 0.0238
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.002 0.0071 0.0065
Echinococcus granulosus alkaline phosphatase 0.016 0.1047 0.1042
Echinococcus multilocularis FTZ F1 alpha 0.002 0.0071 0.0065
Trichomonas vaginalis sphingosine kinase, putative 0.0056 0.0325 0.1781
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0105 0.0664 0.3309
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0058 0.0336 0.033
Schistosoma mansoni 6-phosphofructokinase 0.0105 0.0664 0.0664
Trypanosoma brucei phosphoglycerate kinase 0.0167 0.1099 0.5483
Loa Loa (eye worm) histone methyltransferase 0.0027 0.0122 0.0116
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0032 0.0157 0.077
Entamoeba histolytica T-complex protein 1 beta subunit, putative 0.0024 0.0098 0.0083
Loa Loa (eye worm) bromodomain containing protein 0.0021 0.0078 0.0072
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0066 0.0342
Brugia malayi isocitrate dehydrogenase 0.0016 0.0043 0.0096
Trypanosoma brucei DNA polymerase kappa, putative 0.0078 0.0479 0.2382
Echinococcus multilocularis isocitrate dehydrogenase 0.0016 0.0043 0.0037
Leishmania major T-complex protein 1, beta subunit, putative 0.0024 0.0098 0.0476
Schistosoma mansoni thyroid hormone receptor 0.002 0.0071 0.0071
Echinococcus multilocularis Diacylglycerol kinase theta 0.0056 0.0325 0.0319
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0051 0.0288 0.1425
Trichomonas vaginalis chaperonin-60kD, ch60, putative 0.0024 0.0098 0.0518
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.002 0.0071 0.0071
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0071 0.0161
Brugia malayi Nuclear hormone receptor family member nhr-3 0.002 0.0071 0.0161
Brugia malayi Nuclear hormone receptor family member nhr-31 0.002 0.0071 0.0161
Trichomonas vaginalis DNA helicase recq, putative 0.0045 0.0244 0.1329
Echinococcus multilocularis alkaline phosphatase, intestinal, gene 2 0.016 0.1047 0.1042
Giardia lamblia Histone acetyltransferase GCN5 0.0038 0.0196 0.1424
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.018 0.0886
Brugia malayi Pre-SET motif family protein 0.0031 0.015 0.034
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0107 0.068 0.0675
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0049 0.0007
Mycobacterium tuberculosis Probable lipase LipE 0.0035 0.018 0.0138
Echinococcus multilocularis phosphoglycerate kinase 1 0.0167 0.1099 0.1094
Echinococcus granulosus lysine specific demethylase 6a 0.0015 0.0041 0.0034
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0024 0.0098 0.0052
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0071 0.0065
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0018 0.0061 0.0055
Trichomonas vaginalis bmru protein, putative 0.0056 0.0325 0.1781
Loa Loa (eye worm) beta-lactamase 0.0035 0.018 0.0174
Echinococcus multilocularis beta LACTamase domain containing family member 0.0035 0.018 0.0174
Giardia lamblia Sgs1 DNA helicase, putative 0.0018 0.0061 0.0146
Echinococcus granulosus methyl CpG binding domain protein 2 0.0017 0.005 0.0044
Brugia malayi jmjC domain containing protein 0.0015 0.0041 0.0092
Brugia malayi Phosphoglycerate kinase 0.0061 0.0361 0.0816
Schistosoma mansoni diacylglycerol kinase theta 0.0056 0.0325 0.0325
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0065 0.0385 0.1914
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0027 0.0122 0.0116
Trichomonas vaginalis diacylglycerol kinase, epsilon, putative 0.0056 0.0325 0.1781
Schistosoma mansoni sex comb on midleg homolog 0.0047 0.026 0.026
Schistosoma mansoni hypothetical protein 0.0289 0.1945 0.1945
Trypanosoma brucei DNA polymerase kappa, putative 0.0078 0.0479 0.2382
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0028 0.0131 0.0804
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.002 0.0071 0.0065
Mycobacterium tuberculosis Conserved protein 0.0035 0.018 0.0138
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0027 0.0122 0.0116
Schistosoma mansoni cpg binding protein 0.0091 0.0566 0.0566
Mycobacterium ulcerans bacterioferritin BfrB 0.0025 0.0107 0.0061
Brugia malayi Bromodomain containing protein 0.0082 0.0504 0.114
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0098 0.0474
Trypanosoma brucei DNA polymerase IV, putative 0.0072 0.0434 0.2155
Trypanosoma brucei chrX additional, unordered contigs 0.0016 0.0046 0.0216
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0065 0.0385 0.038
Brugia malayi Diacylglycerol kinase protein 2 0.0056 0.0325 0.0735
Brugia malayi glutaminase DH11.1 0.0269 0.1806 0.4081
Trypanosoma cruzi DNA damage repair protein, putative 0.0016 0.0046 0.0216
Trypanosoma brucei DNA polymerase kappa, putative 0.0059 0.0342 0.1696
Trichomonas vaginalis set domain proteins, putative 0.0235 0.1569 0.8684
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0061 0.0361 0.1793
Onchocerca volvulus 0.0235 0.1571 1
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0032 0.0157 0.077
Echinococcus multilocularis dnaJ subfamily B 0.12 0.8288 0.8287
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0043 0.0037
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0066 0.0342
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0031 0.015 0.015
Loa Loa (eye worm) PHD-finger family protein 0.002 0.0074 0.0068
Toxoplasma gondii phosphoglycerate kinase PGKII 0.0167 0.1099 1
Trypanosoma brucei unspecified product 0.0072 0.0434 0.2155
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0098 0.022
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0017 0.005 0.0044
Loa Loa (eye worm) MH2 domain-containing protein 0.0119 0.0761 0.0755
Schistosoma mansoni alkaline phosphatase 0.016 0.1047 0.1047
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0098 0.0474
Schistosoma mansoni jumonji domain containing protein 0.0015 0.0041 0.0041
Onchocerca volvulus 0.0024 0.0098 0.0621
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0048 0.0267 0.0261
Entamoeba histolytica diacylglycerol kinase, putative 0.0056 0.0325 0.031
Toxoplasma gondii phosphoglycerate kinase PGKI 0.0167 0.1099 1

Activities

Activity type Activity value Assay description Source Reference
Activity (functional) Agonist activity at rat TRPV1 expressed in Xenopus laevis oocytes assessed as stimulation of capsaicin-induced current at holding potential -60 mV at 10 uM by two-microelectrode voltage -clamp amplifier ChEMBL. 21950613
IC50 (functional) = 0.5 uM Antagonist activity at rat TRPV1 expressed in Xenopus laevis oocytes assessed as blockage of capsaicin-induced current at holding potential -60 mV by two-microelectrode voltage -clamp amplifier ChEMBL. 21950613

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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