Detailed information for compound 1653498

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 463.638 | Formula: C26H33N5OS
  • H donors: 0 H acceptors: 1 LogP: 4.09 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: CSc1nc2n(CCCN3CCCCC3)c(c(c2c2=NC(=O)CC(n12)C)C)c1ccccc1
  • InChi: 1S/C26H33N5OS/c1-18-17-21(32)27-25-22-19(2)23(20-11-6-4-7-12-20)30(24(22)28-26(33-3)31(18)25)16-10-15-29-13-8-5-9-14-29/h4,6-7,11-12,18H,5,8-10,13-17H2,1-3H3
  • InChiKey: XWYUCFJURDRGHK-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Entamoeba histolytica cyclin, domain containing protein 0.0077 0.005 0.0227
Brugia malayi Dopamine receptor protein 1 0.0349 0.098 0.1122
Echinococcus multilocularis ubiquitin specific protease 41 0.0082 0.0066 0.006
Trichomonas vaginalis cyclins, putative 0.0391 0.1124 0.2111
Echinococcus multilocularis calpain 7 (C02 family) 0.0322 0.0888 0.0883
Plasmodium falciparum sortilin 0.0283 0.0753 0.8611
Onchocerca volvulus Putative endochitinase 0.04 0.1154 0.5917
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0071 0.0029 0.0024
Loa Loa (eye worm) hypothetical protein 0.0077 0.005 0.0057
Echinococcus granulosus lysine specific histone demethylase 1A 0.0482 0.1433 0.1428
Echinococcus multilocularis cdk5 and abl1 enzyme substrate 1 0.0077 0.005 0.0044
Trypanosoma cruzi Cysteine peptidase, Clan CF, family C15 0.045 0.1325 0.4837
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0245 0.0623 0.1164
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0289 0.0775 0.0814
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 14 0.0074 0.0041 0.0035
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.012 0.0198 0.0363
Trypanosoma cruzi AUT2/APG4/ATG4 cysteine peptidase, putative 0.0205 0.0487 0.1766
Onchocerca volvulus 0.0349 0.098 0.502
Toxoplasma gondii kringle domain-containing protein 0.0178 0.0397 0.507
Giardia lamblia Cathepsin B precursor 0.0115 0.0181 0.0578
Trypanosoma brucei cyclin 3 0.0077 0.005 0.0161
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase isozyme L3 0.0131 0.0233 0.2622
Entamoeba histolytica cyclin, putative 0.0318 0.0874 0.447
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0421 0.1224 0.4466
Loa Loa (eye worm) hypothetical protein 0.0219 0.0537 0.0614
Loa Loa (eye worm) hypothetical protein 0.0349 0.098 0.1122
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0081 0.0064 0.011
Brugia malayi RE15519p 0.0349 0.098 0.1122
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.012 0.0198 0.0363
Onchocerca volvulus 0.0245 0.0623 0.3181
Leishmania major hypothetical protein, conserved 0.0281 0.0746 0.2715
Loa Loa (eye worm) hypothetical protein 0.0214 0.0519 0.0595
Entamoeba histolytica cell division protein kinase 2, putative 0.0087 0.0084 0.0404
Trypanosoma cruzi Domain of unknown function (DUF1935), putative 0.0281 0.0746 0.2715
Schistosoma mansoni integrin beta subunit 0.0191 0.0438 0.0458
Entamoeba histolytica cysteine proteinase 1, putative 0.0129 0.0228 0.1146
Echinococcus multilocularis cyclins 0.0318 0.0874 0.0869
Leishmania major AUT2/APG4/ATG4 cysteine peptidase, putative 0.0086 0.0081 0.0279
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0163 0.0345 0.1244
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0229 0.0569 0.1063
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0118 0.0191 0.0681
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0683 0.2121 0.775
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0349 0.098 0.1122
Loa Loa (eye worm) hypothetical protein 0.0174 0.0383 0.0439
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0229 0.0569 0.1063
Loa Loa (eye worm) calpain D 0.0301 0.0815 0.0933
Echinococcus granulosus integrin alpha ps 0.0068 0.002 0.0014
Schistosoma mansoni cathepsin F (C01 family) 0.0245 0.0623 0.0653
Schistosoma mansoni amine GPCR 0.0349 0.098 0.1031
Trypanosoma brucei cysteine peptidase, Clan CA, family C51, putative 0.0327 0.0904 0.3292
Plasmodium falciparum deubiquinating/deneddylating enzyme 0.0118 0.0191 0.2127
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0245 0.0623 0.1164
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0426 0.1243 0.4534
Schistosoma mansoni family M1 non-peptidase homologue (M01 family) 0.0069 0.0023 0.0019
Brugia malayi Myb-like DNA-binding domain containing protein 0.0176 0.0388 0.0445
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0067 0.0018 0.0023
Giardia lamblia Cathepsin B precursor 0.0115 0.0181 0.0578
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.012 0.0198 0.0363
Trichomonas vaginalis cyclins, putative 0.0077 0.005 0.0083
Loa Loa (eye worm) hypothetical protein 0.0219 0.0537 0.0614
Leishmania major mitotic cyclin, putative 0.0077 0.005 0.0165
Echinococcus granulosus neuropeptide Y receptor 0.0349 0.098 0.0975
Brugia malayi neuropeptide F receptor 0.0349 0.098 0.1122
Schistosoma mansoni cyclin B 0.0633 0.1948 0.2056
Leishmania major hypothetical protein, conserved 0.0178 0.0397 0.1436
Echinococcus granulosus G1:S specific cyclin D1 0.0077 0.005 0.0044
Brugia malayi G-protein coupled receptor 0.0349 0.098 0.1122
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0106 0.0151 0.0145
Brugia malayi neuropeptide F receptor 0.0349 0.098 0.1122
Brugia malayi Endochitinase 0.04 0.1154 0.1322
Echinococcus multilocularis calpain 5 0.0289 0.0775 0.0769
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0178 0.0397 0.4665
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0138 0.0258 0.0928
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase 5, putative 0.0084 0.0074 0.035
Trichomonas vaginalis conserved hypothetical protein 0.0544 0.1644 0.3092
Loa Loa (eye worm) ctsf protein 0.0245 0.0623 0.0713
Schistosoma mansoni family M13 non-peptidase homologue (M13 family) 0.0071 0.0029 0.0024
Schistosoma mansoni neuropeptide receptor 0.0349 0.098 0.1031
Echinococcus multilocularis rhodopsin orphan GPCR 0.0349 0.098 0.0975
Trypanosoma brucei calpain-like protein, putative 0.0289 0.0775 0.2818
Brugia malayi GPI-anchor transamidase 0.0064 0.0006 0.0007
Echinococcus multilocularis Furin 1 0.0664 0.2054 0.205
Trypanosoma cruzi cysteine peptidase, Clan CA, family C54, putative 0.0205 0.0487 0.1766
Loa Loa (eye worm) hypothetical protein 0.029 0.0778 0.0891
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0626 0.1925 0.7035
Schistosoma mansoni calpain (C02 family) 0.0289 0.0775 0.0814
Plasmodium falciparum protein kinase 5 0.0087 0.0084 0.0903
Schistosoma mansoni ubiquitin-specific peptidase 42 (C19 family) 0.0067 0.0018 0.0013
Echinococcus granulosus neuropeptide FF receptor 2 0.105 0.3372 0.3368
Trypanosoma brucei Calpain-like protein 2 0.0641 0.1976 0.7221
Echinococcus multilocularis rhodopsin orphan GPCR 0.0349 0.098 0.0975
Echinococcus granulosus neuropeptides capa receptor 0.0349 0.098 0.0975
Trypanosoma brucei hypothetical protein 0.0503 0.1503 0.5488
Echinococcus multilocularis cathepsin b 0.0115 0.0181 0.0175
Echinococcus granulosus cyclin y 0.0077 0.005 0.0044
Plasmodium vivax subtilisin-like protease 1 0.012 0.0198 0.2293
Mycobacterium tuberculosis Probable alanine and proline rich membrane-anchored mycosin MycP2 (serine protease) (subtilisin-like protease) (subtilase-like) 0.012 0.0198 0.0912
Leishmania major ubiqitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0109 0.0158 0.0562
Brugia malayi Melatonin receptor type 1A 0.0349 0.098 0.1122
Brugia malayi ORL1-like opioid receptor 0.0349 0.098 0.1122
Toxoplasma gondii subtilisin SUB1 0.012 0.0198 0.2499
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0221 0.0542 0.1966
Onchocerca volvulus 0.0144 0.0278 0.1411
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0563 0.1709 0.6243
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0692 0.2149 0.7855
Loa Loa (eye worm) peptidase family M13 containing protein 0.0214 0.0519 0.0595
Echinococcus multilocularis endothelin converting enzyme 1 0.029 0.0778 0.0772
Schistosoma mansoni hypothetical protein 0.0349 0.098 0.1031
Echinococcus multilocularis Peptidase S8 S53, subtilisin kexin sedolisin 0.012 0.0198 0.0192
Trypanosoma brucei cyclin 9 0.0077 0.005 0.0161
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0115 0.0181 0.0185
Onchocerca volvulus 0.0245 0.0623 0.3181
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase, putative 0.0067 0.0018 0.014
Echinococcus granulosus Cyclin L1 0.0077 0.005 0.0044
Echinococcus granulosus furin 0.262 0.8733 0.8732
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0245 0.0623 0.7103
Schistosoma mansoni family C12 unassigned peptidase (C12 family) 0.0131 0.0233 0.0241
Trypanosoma brucei calpain, putative 0.0229 0.0569 0.2064
Toxoplasma gondii cathepsin CPL 0.0245 0.0623 0.7991
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0245 0.0623 0.1164
Trypanosoma cruzi hypothetical protein, conserved 0.0281 0.0746 0.2715
Trypanosoma brucei otubain cysteine peptidase, Clan CA, family C65, putative 0.009 0.0095 0.0325
Loa Loa (eye worm) cyclin fold protein 1 variant b 0.0077 0.005 0.0057
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0084 0.0074 0.0249
Brugia malayi hypothetical protein 0.0349 0.098 0.1122
Echinococcus granulosus cathepsin l1 0.0166 0.0354 0.0348
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0163 0.0345 0.1247
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0115 0.0181 0.0185
Leishmania major PFPI/DJ-1-like protein, putative 0.0473 0.1401 0.5116
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0245 0.0623 0.1164
Trypanosoma cruzi cyclin, putative 0.0633 0.1948 0.712
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0067 0.0018 0.0045
Echinococcus granulosus G2:mitotic specific cyclin B3 0.0318 0.0874 0.0869
Trichomonas vaginalis ubiquitin specific protease, putative 0.0066 0.0013 0.0014
Echinococcus multilocularis G-protein coupled receptor, putative 0.0349 0.098 0.0975
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0349 0.098 0.1122
Schistosoma mansoni hypothetical protein 0.0069 0.0024 0.002
Loa Loa (eye worm) hypothetical protein 0.0229 0.0569 0.0652
Schistosoma mansoni family A2 unassigned peptidase (A02 family) 0.0468 0.1385 0.146
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0106 0.0151 0.0145
Brugia malayi Protein kinase domain containing protein 0.0087 0.0084 0.0096
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0349 0.098 0.0975
Trypanosoma brucei Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative 0.0076 0.0048 0.0153
Entamoeba histolytica chitinase, putative 0.04 0.1154 0.5913
Trypanosoma cruzi hypothetical protein, conserved 0.0178 0.0397 0.1436
Entamoeba histolytica calpain family cysteine protease, putative 0.0301 0.0815 0.4163
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0245 0.0623 0.0617
Onchocerca volvulus 0.0349 0.098 0.502
Brugia malayi Cathepsin L-like precursor 0.0245 0.0623 0.0713
Schistosoma mansoni site-1 peptidase (S08 family) 0.012 0.0198 0.0203
Mycobacterium ulcerans chitinase/cellulase 0.0341 0.0953 1
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.012 0.0198 0.0363
Schistosoma mansoni family C12 unassigned peptidase (C12 family) 0.0131 0.0233 0.0241
Plasmodium vivax hypothetical protein, conserved 0.0077 0.005 0.0526
Schistosoma mansoni histamine h1 receptor 0.0349 0.098 0.1031
Leishmania major hypothetical protein, conserved,calpain-like cysteine peptidase, Clan CA, family C2 0.0588 0.1795 0.6559
Onchocerca volvulus 0.0349 0.098 0.502
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0243 0.0618 0.2246
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0245 0.0623 0.1164
Plasmodium vivax vivapain-2 0.0245 0.0623 0.7361
Leishmania major small myristoylated protein-2 0.0743 0.2326 0.8503
Schistosoma mansoni hypothetical protein 0.2832 0.9455 1
Echinococcus granulosus Furin 1 0.0664 0.2054 0.205
Toxoplasma gondii subtilisin SUB2 0.012 0.0198 0.2499
Schistosoma mansoni cyclin G 0.0077 0.005 0.0047
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0392 0.1128 0.4111
Onchocerca volvulus 0.0178 0.0397 0.202
Echinococcus granulosus 7TM GPCR rhodopsin 0.0349 0.098 0.0975
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 46 0.0076 0.0048 0.0055
Schistosoma mansoni neprilysin 0.0076 0.0046 0.0043
Loa Loa (eye worm) chitinase I 0.04 0.1154 0.1322
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0236 0.0592 0.0587
Brugia malayi larval opioid receptor 0.0349 0.098 0.1122
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.012 0.0198 0.0363
Schistosoma mansoni hypothetical protein 0.0076 0.0046 0.0043
Brugia malayi Ubiquitin carboxyl-terminal hydrolase, family 1 protein 0.0131 0.0233 0.0267
Schistosoma mansoni neuropeptide F-like receptor 0.0349 0.098 0.1031
Toxoplasma gondii cyclin, N-terminal domain-containing protein 0.0077 0.005 0.0584
Entamoeba histolytica cyclin, domain containing protein 0.0077 0.005 0.0227
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0129 0.0228 0.0816
Loa Loa (eye worm) hypothetical protein 0.0085 0.0079 0.0091
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0664 0.2054 0.3867
Echinococcus multilocularis G2:mitotic specific cyclin B3 0.0318 0.0874 0.0869
Schistosoma mansoni hypothetical protein 0.0349 0.098 0.1031
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0349 0.098 0.0975
Brugia malayi Cathepsin L-like precursor 0.0166 0.0354 0.0405
Plasmodium falciparum subtilisin-like protease 3 0.012 0.0198 0.2212
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0271 0.0713 0.2595
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0349 0.098 0.0975
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase isozyme 0.0118 0.0191 0.0185
Entamoeba histolytica cysteine proteinase, putative 0.0245 0.0623 0.3174
Echinococcus multilocularis allatostatin A receptor 0.0349 0.098 0.0975
Trichomonas vaginalis proprotein convertase subtilisin/kexin type, putative 0.0544 0.1644 0.3092
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.012 0.0198 0.0363
Entamoeba histolytica cyclin family protein 0.0318 0.0874 0.447
Loa Loa (eye worm) hypothetical protein 0.0349 0.098 0.1122
Onchocerca volvulus Putative endochitinase 0.04 0.1154 0.5917
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0067 0.0018 0.0063
Echinococcus granulosus Peptidase C54 0.0086 0.0081 0.0075
Trypanosoma brucei cysteine peptidase, Clan CA, family C51, putative 0.0327 0.0904 0.3292
Trypanosoma cruzi hypothetical protein, conserved 0.0281 0.0746 0.2715
Giardia lamblia Hypothetical protein 0.0077 0.005 0.0145
Echinococcus granulosus cyclin t1 0.0077 0.005 0.0044
Trichomonas vaginalis cyclin A, putative 0.0633 0.1948 0.3667
Trichomonas vaginalis Clan CA, family C12, ubiquitin hydrolase-like cysteine peptidase 0.0131 0.0233 0.043
Echinococcus granulosus cathepsin l1 0.0245 0.0623 0.0617
Echinococcus multilocularis g protein coupled receptor 0.0349 0.098 0.0975
Brugia malayi hypothetical protein 0.0106 0.0151 0.0173
Brugia malayi G-protein coupled receptor 0.0349 0.098 0.1122
Trypanosoma cruzi cysteine protease, putative 0.0129 0.0228 0.082
Giardia lamblia High cysteine membrane protein Group 2 0.0952 0.3037 1
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0138 0.0258 0.0928
Plasmodium vivax cyclin 4, putative 0.0077 0.005 0.0526
Echinococcus multilocularis protoporphyrinogen oxidase 0.0098 0.0122 0.0116
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase, putative 0.0074 0.0041 0.0422
Trypanosoma brucei Calpain-like protein 1.1 0.0863 0.2735 1
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0079 0.0056 0.0065
Loa Loa (eye worm) hypothetical protein 0.0523 0.1572 0.18
Mycobacterium ulcerans membrane-anchored serine protease (mycosin), MycP4 0.012 0.0198 0.0912
Echinococcus granulosus fmrfamide receptor 0.0349 0.098 0.0975
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0349 0.098 0.0975
Leishmania major hypothetical protein, conserved 0.0454 0.1338 0.4883
Leishmania major hypothetical protein, conserved 0.0281 0.0746 0.2715
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0392 0.1128 0.4111
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0082 0.0066 0.0221
Toxoplasma gondii cyclin domain protein, cyclin H family protein 0.0077 0.005 0.0584
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0245 0.0623 0.1164
Schistosoma mansoni calpain-7 (C02 family) 0.0368 0.1045 0.11
Schistosoma mansoni subfamily S8B unassigned peptidase (S08 family) 0.262 0.8733 0.9236
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.012 0.0198 0.0363
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase 5, putative 0.0163 0.0345 0.1747
Loa Loa (eye worm) hypothetical protein 0.0219 0.0537 0.0614
Trypanosoma brucei small myristoylated protein 1-2 0.0437 0.128 0.4671
Brugia malayi Cyclin, N-terminal domain containing protein 0.0633 0.1948 0.2231
Schistosoma mansoni cyclin l 0.0077 0.005 0.0047
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0664 0.2054 0.3867
Loa Loa (eye worm) hypothetical protein 0.0349 0.098 0.1122
Brugia malayi Cyclin, N-terminal domain containing protein 0.0077 0.005 0.0057
Loa Loa (eye worm) hypothetical protein 0.029 0.0778 0.0891
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0349 0.098 0.1031
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0245 0.0623 0.0617
Trypanosoma cruzi UDP-galactopyranose mutase 0.0098 0.0122 0.043
Echinococcus multilocularis cyclins 0.0318 0.0874 0.0869
Leishmania major D-alanyl-glycyl endopeptidase-like protein,cysteine peptidase, Clan CA, family C51, putative 0.0327 0.0904 0.3295
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0084 0.0074 0.0128
Schistosoma mansoni sortilin 0.02 0.0472 0.0493
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0863 0.2735 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0392 0.1128 0.4111
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.012 0.0198 0.0363
Plasmodium falciparum cysteine proteinase falcipain 3 0.0245 0.0623 0.7103
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0067 0.0018 0.0049
Schistosoma mansoni serine/threonine protein kinase 0.0087 0.0084 0.0083
Trypanosoma cruzi cysteine peptidase, Clan CA, family C19, putative 0.0109 0.0158 0.0562
Loa Loa (eye worm) hypothetical protein 0.0349 0.098 0.1122
Mycobacterium ulcerans proline rich membrane-anchored mycosin MycP5 0.012 0.0198 0.0912
Schistosoma mansoni cyclin d 0.0077 0.005 0.0047
Entamoeba histolytica cysteine protease inhibitor 2 (EhICP2) 0.0245 0.0624 0.3182
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0349 0.098 0.1122
Brugia malayi celfurPC protein 0.2077 0.6877 0.7874
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0106 0.0151 0.0145
Echinococcus granulosus cathepsin L cysteine proteinase 0.0245 0.0623 0.0617
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0067 0.0018 0.0172
Echinococcus multilocularis cyclin G2 0.0077 0.005 0.0044
Entamoeba histolytica cysteine protease, putative 0.0129 0.0228 0.1146
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase isozyme L3, putative 0.0131 0.0233 0.2717
Leishmania major inhibitor of cysteine peptidase 0.0245 0.0624 0.2268
Onchocerca volvulus 0.0349 0.098 0.502
Loa Loa (eye worm) hypothetical protein 0.0349 0.098 0.1122
Onchocerca volvulus 0.0349 0.098 0.502
Plasmodium vivax hypothetical protein, conserved 0.0098 0.0122 0.1387
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0595 0.1819 0.6647
Brugia malayi Integrin alpha cytoplasmic region family protein 0.0239 0.0604 0.0692
Schistosoma mansoni serine/threonine protein kinase 0.0236 0.0592 0.0621
Trypanosoma cruzi subtilisin-like serine peptidase, putative 0.012 0.0198 0.0708
Schistosoma mansoni endothelin-converting enzyme-like 1 (damage-induced neuronal endopeptidase) 0.0071 0.0029 0.0024
Brugia malayi calpain D 0.0301 0.0815 0.0933
Plasmodium vivax hypothetical protein, conserved 0.0098 0.0122 0.1387
Trypanosoma cruzi cruzipain precursor, putative 0.0079 0.0056 0.0189
Echinococcus granulosus 7tm_1 domain containing protein 0.0349 0.098 0.0975
Echinococcus granulosus cyclin dependent kinase 1 0.0087 0.0084 0.0078
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0221 0.0542 0.1966
Echinococcus granulosus G protein coupled receptor 139 0.0349 0.098 0.0975
Echinococcus multilocularis ubiquitin specific peptidase 42 (C19 family) 0.0067 0.0018 0.0012
Schistosoma mansoni hypothetical protein 0.0083 0.0069 0.0067
Trichomonas vaginalis conserved hypothetical protein 0.0544 0.1644 0.3092
Echinococcus granulosus cyclin B3 1 0.0318 0.0874 0.0869
Trypanosoma cruzi cysteine peptidase, Clan CA, family C19, putative 0.0243 0.0618 0.2246
Schistosoma mansoni hypothetical protein 0.0077 0.005 0.0047
Trichomonas vaginalis conserved hypothetical protein 0.0544 0.1644 0.3092
Trichomonas vaginalis cyclin D, putative 0.0077 0.005 0.0083
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0818 0.258 0.9435
Onchocerca volvulus Neuropeptide F receptor homolog 0.0349 0.098 0.502
Schistosoma mansoni cathepsin s 0.0079 0.0056 0.0053
Loa Loa (eye worm) hypothetical protein 0.0217 0.0529 0.0606
Trichomonas vaginalis cyclin B3, putative 0.0318 0.0874 0.1639
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0229 0.0569 0.1063
Trypanosoma cruzi cysteine peptidase, putative 0.0079 0.0056 0.0189
Loa Loa (eye worm) hypothetical protein 0.0098 0.0122 0.014
Echinococcus multilocularis integrin alpha ps 0.0068 0.002 0.0014
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0076 0.0046 0.0043
Leishmania major cathepsin L-like protease 0.0392 0.1128 0.4113
Schistosoma mansoni hypothetical protein 0.0076 0.0046 0.0043
Schistosoma mansoni ubiquitin-specific peptidase 5 (C19 family) 0.0084 0.0074 0.0072
Echinococcus multilocularis cyclin b3 0.0318 0.0874 0.0869
Echinococcus multilocularis integrin beta 2 0.024 0.0606 0.0601
Leishmania major hypothetical protein, conserved 0.0281 0.0746 0.2715
Trypanosoma cruzi trypanothione synthetase, putative 0.0071 0.0029 0.0087
Echinococcus multilocularis cysteine protease atg4b 0.0086 0.0081 0.0075
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.012 0.0198 0.0363
Giardia lamblia G2/mitotic-specific cyclin B 0.0633 0.1948 0.6409
Onchocerca volvulus Cyclin L homolog 0.0077 0.005 0.0236
Echinococcus granulosus rhodopsin orphan GPCR 0.0349 0.098 0.0975
Brugia malayi Peptidase family M1 containing protein 0.0106 0.0151 0.0173
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0486 0.1448 0.5288
Echinococcus granulosus cyclin 0.0077 0.005 0.0044
Schistosoma mansoni neuropeptide F-like receptor 0.0349 0.098 0.1031
Echinococcus multilocularis ubiquitin specific peptidase (c family) ubiquitin terminal hydrolase 0.0138 0.0258 0.0252
Trypanosoma brucei unspecified product 0.0281 0.0746 0.2712
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.038 0.1086 0.3961
Echinococcus granulosus cyclin G2 0.0077 0.005 0.0044
Onchocerca volvulus 0.0349 0.098 0.502
Echinococcus multilocularis neuropeptide receptor 0.0349 0.098 0.0975
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0129 0.0228 0.0816
Schistosoma mansoni family C54 unassigned peptidase (C54 family) 0.0086 0.0081 0.008
Echinococcus multilocularis dro:myosuppressin receptor 0.0349 0.098 0.0975
Brugia malayi endochitinase 0.04 0.1154 0.1322
Echinococcus granulosus cysteine protease 0.0129 0.0228 0.0223
Echinococcus multilocularis cathepsin L cysteine protease 0.0245 0.0623 0.0617
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0291 0.0782 0.2845
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0349 0.098 0.0975
Trypanosoma cruzi cysteine peptidase, putative 0.0129 0.0228 0.082
Loa Loa (eye worm) peptidase family M13 containing protein 0.0214 0.0519 0.0595
Onchocerca volvulus 0.0077 0.005 0.0236
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0245 0.0623 0.1164
Trypanosoma brucei AUT2/APG4/ATG4 cysteine peptidase, putative 0.0086 0.0081 0.0275
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0245 0.0623 0.1164
Echinococcus granulosus biogenic amine 5HT receptor 0.0349 0.098 0.0975
Schistosoma mansoni integrin alpha-ps 0.0142 0.0271 0.0281
Leishmania major ubiquitin carboxyl-terminal hydrolase, putative,cysteine peptidase, Clan CA, family C12, putative 0.0131 0.0233 0.0838
Echinococcus multilocularis cathepsin b 0.0115 0.0181 0.0175
Loa Loa (eye worm) hypothetical protein 0.0248 0.0635 0.0727
Loa Loa (eye worm) hypothetical protein 0.0245 0.0623 0.0713
Loa Loa (eye worm) integrin beta-2 0.0324 0.0893 0.1022
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0276 0.073 0.2653
Mycobacterium tuberculosis Probable epoxide hydrolase EphA (epoxide hydratase) (arene-oxide hydratase) 0.0168 0.0363 0.2895
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0115 0.0181 0.0645
Plasmodium vivax ubiquitin C-terminal hydrolase, family 1, putative 0.0118 0.0191 0.2205
Brugia malayi putative neuropeptide receptor NPR1 0.0349 0.098 0.1122
Brugia malayi calpain family protein 1 0.0289 0.0775 0.0887
Onchocerca volvulus 0.0245 0.0623 0.3181
Echinococcus granulosus ubiquitin specific protease 41 0.0082 0.0066 0.006
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0274 0.0722 0.2624
Loa Loa (eye worm) hypothetical protein 0.0349 0.098 0.1122
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0071 0.0029 0.0024
Echinococcus multilocularis rhodopsin orphan GPCR 0.0349 0.098 0.0975
Schistosoma mansoni family C19 unassigned peptidase (C19 family) 0.0109 0.0158 0.0161
Schistosoma mansoni family C54 unassigned peptidase (C54 family) 0.0086 0.0081 0.008
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0271 0.0713 0.2595
Echinococcus multilocularis cathepsin L 0.0129 0.0228 0.0223
Leishmania major small myristoylated protein-3, putative 0.038 0.1086 0.3961
Schistosoma mansoni furin-1 (S08 family) 0.1125 0.3628 0.3833
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0138 0.0258 0.0476
Leishmania major UDP-galactopyranose mutase 0.0098 0.0122 0.043
Brugia malayi hypothetical protein 0.0349 0.098 0.1122
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0634 0.1953 0.7138
Loa Loa (eye worm) calpain family protein 1 0.0229 0.0569 0.0652
Schistosoma mansoni g1/s-specific cyclin C 0.0077 0.005 0.0047
Schistosoma mansoni cyclin B3 0.0318 0.0874 0.0919
Loa Loa (eye worm) hypothetical protein 0.0139 0.0261 0.0299
Plasmodium falciparum cysteine repeat modular protein 1 0.0178 0.0397 0.4501
Brugia malayi Hypothetical subtilase-type proteinase F21H12.6 in chromosome II 0.012 0.0198 0.0227
Echinococcus multilocularis somatostatin receptor 0.0349 0.098 0.0975
Loa Loa (eye worm) hypothetical protein 0.0349 0.098 0.1122
Echinococcus granulosus cyclin dependent kinase 0.0087 0.0084 0.0078
Loa Loa (eye worm) calpain family protein 1 0.0289 0.0775 0.0887
Plasmodium falciparum cyclin dependent kinase binding protein, putative 0.0077 0.005 0.0507
Echinococcus multilocularis expressed protein 0.0765 0.2401 0.2396
Loa Loa (eye worm) hypothetical protein 0.0349 0.098 0.1122
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 36 0.0067 0.0018 0.0012
Schistosoma mansoni hypothetical protein 0.0076 0.0046 0.0043
Echinococcus granulosus sex peptide receptor 0.0349 0.098 0.0975
Onchocerca volvulus CoRest homolog 0.0181 0.0406 0.2067
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.012 0.0198 0.0363
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0243 0.0618 0.2243
Brugia malayi Peptidase family M13 containing protein 0.029 0.0778 0.0891
Brugia malayi Furin-like cysteine rich region family protein 0.0294 0.0792 0.0907
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0067 0.0018 0.0049
Echinococcus granulosus cyclins 0.0318 0.0874 0.0869
Loa Loa (eye worm) cysteine protease 0.0245 0.0623 0.0713
Trichomonas vaginalis cyclin B, putative 0.0633 0.1948 0.3667
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 23 0.0067 0.0018 0.0012
Loa Loa (eye worm) hypothetical protein 0.0229 0.0569 0.0652
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 7 0.0081 0.0064 0.0058
Leishmania major cytoskeleton-associated protein CAP5.5, putative,cysteine peptidase, Clan CA, family C2, putative 0.0595 0.1819 0.6647
Schistosoma mansoni neuropeptide receptor 0.0349 0.098 0.1031
Loa Loa (eye worm) subtilase 0.012 0.0198 0.0227
Schistosoma mansoni ubiquitinyl hydrolase-UCH37 (C12 family) 0.0118 0.0191 0.0195
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0243 0.0618 0.2246
Mycobacterium ulcerans zinc metalloprotease 0.029 0.0778 0.789
Trypanosoma brucei META domain/Domain of unknown function (DUF1935), putative 0.0281 0.0746 0.2712
Loa Loa (eye worm) TYRA-2 protein 0.0349 0.098 0.1122
Trypanosoma cruzi cysteine peptidase, Clan CA, family C48, putative 0.0188 0.0431 0.1561
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0082 0.0066 0.006
Trypanosoma cruzi calpain cysteine peptidase, putative 0.051 0.1527 0.5577
Trypanosoma brucei calpain-like protein, putative 0.0563 0.1709 0.6242
Echinococcus multilocularis baculoviral IAP repeat containing protein 0.0217 0.0529 0.0523
Echinococcus multilocularis cyclin k 0.0077 0.005 0.0044
Toxoplasma gondii hypothetical protein 0.0241 0.0612 0.7854
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.012 0.0198 0.0363
Trichomonas vaginalis conserved hypothetical protein 0.0544 0.1644 0.3092
Trichomonas vaginalis conserved hypothetical protein 0.0544 0.1644 0.3092
Loa Loa (eye worm) hypothetical protein 0.0349 0.098 0.1122
Leishmania major ubiquitin carboxyl-terminal hydrolase, putative,cysteine peptidase, Clan CA, family C12, putative 0.0118 0.0191 0.0681
Echinococcus multilocularis Peptidase M1, membrane alanine aminopeptidase, N terminal 0.0106 0.0151 0.0145
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0349 0.098 0.1122
Loa Loa (eye worm) cyclin domain-containing protein 0.0077 0.005 0.0057
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0082 0.0066 0.0076
Trichomonas vaginalis conserved hypothetical protein 0.0544 0.1644 0.3092
Schistosoma mansoni ubiquitinyl hydrolase-UCH37 (C12 family) 0.0118 0.0191 0.0195
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.012 0.0198 0.0363
Echinococcus granulosus cathepsin L cysteine protease 0.0129 0.0228 0.0223
Echinococcus multilocularis hypothetical protein 0.0289 0.0775 0.0769
Leishmania major cysteine peptidase A (CPA) 0.0245 0.0623 0.2263
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0084 0.0074 0.0253
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0243 0.0618 0.2246
Loa Loa (eye worm) cyclin domain-containing protein 0.0077 0.005 0.0057
Echinococcus granulosus expressed protein 0.0765 0.2401 0.2396
Schistosoma mansoni tyrosine kinase 0.0294 0.0792 0.0832
Leishmania major AUT2/APG4/ATG4 cysteine peptidase, putative 0.0205 0.0487 0.1766
Echinococcus multilocularis integrin alpha 3 0.0242 0.0615 0.0609
Brugia malayi ubiquitin carboxyl-terminal hydrolase 46 0.0076 0.0048 0.0055
Trichomonas vaginalis conserved hypothetical protein 0.0544 0.1644 0.3092
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0106 0.0151 0.0145
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0392 0.1128 0.4111
Schistosoma mansoni cyclin G2 0.0077 0.005 0.0047
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0138 0.0258 0.1299
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0245 0.0623 0.1164
Loa Loa (eye worm) hypothetical protein 0.0341 0.0953 0.1091
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0349 0.098 0.1122
Schistosoma mansoni calpain C (C02 family) 0.0289 0.0775 0.0814
Schistosoma mansoni hypothetical protein 0.0308 0.084 0.0883
Giardia lamblia Furin precursor putative serine protease 0.0544 0.1644 0.5405
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0081 0.0064 0.011
Trypanosoma cruzi trypanothione synthetase 0.0071 0.0029 0.0087
Brugia malayi GnHR receptor homolog 0.0349 0.098 0.1122
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.038 0.1086 0.3961
Leishmania major D-alanyl-glycyl endopeptidase-like protein,cysteine peptidase, Clan CA, family C51, putative 0.0327 0.0904 0.3295
Schistosoma mansoni subfamily S8B unassigned peptidase (S08 family) 0.012 0.0198 0.0203
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0069 0.0023 0.0018
Entamoeba histolytica cysteine protease, putative 0.0129 0.0228 0.1146
Trypanosoma brucei cysteine peptidase, Clan CA, family C19, putative 0.0109 0.0158 0.0559
Brugia malayi Cathepsin L-like precursor 0.0166 0.0354 0.0405
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0067 0.0018 0.0023
Loa Loa (eye worm) hypothetical protein 0.0349 0.098 0.1122
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0064 0.0008 0.0008
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0281 0.0746 0.2715
Schistosoma mansoni autophagin-1 (C54 family) 0.0086 0.0081 0.008
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0138 0.0258 0.0476
Loa Loa (eye worm) hypothetical protein 0.0068 0.002 0.0022
Trypanosoma cruzi Aminopeptidase M1, putative 0.0106 0.0151 0.0536
Trichomonas vaginalis cyclin D, putative 0.0318 0.0874 0.1639
Loa Loa (eye worm) hypothetical protein 0.0349 0.098 0.1122
Echinococcus multilocularis cyclin B3 1 0.0318 0.0874 0.0869
Plasmodium vivax protoporphyrinogen oxidase, putative 0.0098 0.0122 0.1387
Loa Loa (eye worm) hypothetical protein 0.0349 0.098 0.1122
Trypanosoma cruzi hypothetical protein, conserved 0.0281 0.0746 0.2715
Trichomonas vaginalis cyclin B, putative 0.0077 0.005 0.0083
Brugia malayi Trypsin family protein 0.0417 0.121 0.1386
Brugia malayi cyclin fold protein 1 variant b 0.0077 0.005 0.0057
Echinococcus granulosus rhodopsin orphan GPCR 0.0349 0.098 0.0975
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0349 0.098 0.1031
Loa Loa (eye worm) hypothetical protein 0.0349 0.098 0.1122
Schistosoma mansoni endothelin-converting enzyme-related 0.0071 0.0029 0.0024
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.1616 0.5304 1
Brugia malayi Tachykinin-like peptides receptor 99D 0.105 0.3372 0.3861
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0349 0.098 0.1031
Brugia malayi hypothetical protein 0.0349 0.098 0.1122
Plasmodium vivax subtilisin-like protease 2, putative 0.012 0.0198 0.2293
Brugia malayi hypothetical protein 0.0077 0.005 0.0057
Schistosoma mansoni integrin alpha 0.0316 0.0867 0.0911
Trichomonas vaginalis cyclin B3, putative 0.0077 0.005 0.0083
Leishmania major hypothetical protein, conserved 0.0281 0.0746 0.2715
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0162 0.0342 0.0355
Loa Loa (eye worm) hypothetical protein 0.0166 0.0354 0.0405
Brugia malayi Kringle domain containing protein 0.0178 0.0397 0.0454
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase isozyme 0.0118 0.0191 0.0185
Loa Loa (eye worm) hypothetical protein 0.0349 0.098 0.1122
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0426 0.1243 0.4534
Loa Loa (eye worm) cyclin domain-containing protein 0.0077 0.005 0.0057
Trypanosoma brucei antigen, putative 0.0289 0.0775 0.2818
Trypanosoma brucei Aminopeptidase M1, putative 0.0106 0.0151 0.0533
Schistosoma mansoni hypothetical protein 0.0544 0.1644 0.1734
Entamoeba histolytica cysteine protease, putative 0.0129 0.0228 0.1146
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0291 0.0782 0.2848
Echinococcus granulosus cyclin G2 0.0077 0.005 0.0044
Echinococcus granulosus cyclins 0.0077 0.005 0.0044
Trypanosoma brucei calpain-like protein, putative 0.0309 0.0844 0.307
Echinococcus granulosus cyclin y 0.0077 0.005 0.0044
Echinococcus granulosus g-protein coupled receptor 0.0349 0.098 0.0975
Entamoeba histolytica cysteine protease, putative 0.0129 0.0228 0.1146
Plasmodium falciparum lysine-specific histone demethylase 1, putative 0.0098 0.0122 0.1339
Trypanosoma cruzi trypanothione synthetase-like protein, putative 0.0071 0.0029 0.0087
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.066 0.204 0.7454
Trichomonas vaginalis conserved hypothetical protein 0.0077 0.005 0.0083
Loa Loa (eye worm) hypothetical protein 0.0349 0.098 0.1122
Loa Loa (eye worm) hypothetical protein 0.0349 0.098 0.1122
Onchocerca volvulus 0.012 0.0198 0.0998
Brugia malayi Integrin alpha pat-2 precursor 0.0316 0.0867 0.0993
Loa Loa (eye worm) proprotein convertase 2 0.0664 0.2054 0.2352
Loa Loa (eye worm) hypothetical protein 0.0349 0.098 0.1122
Schistosoma mansoni neprilysin-2 (M13 family) 0.0146 0.0287 0.0298
Loa Loa (eye worm) G-protein coupled receptor 0.0349 0.098 0.1122
Toxoplasma gondii subtilisin SUB6 0.012 0.0198 0.2499
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0863 0.2735 1
Echinococcus granulosus aminopeptidase N 0.0362 0.1023 0.1017
Trypanosoma cruzi hypothetical protein, conserved 0.0071 0.0029 0.0087
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0349 0.098 0.0975
Leishmania major cyclin 9, putative 0.0077 0.005 0.0165
Loa Loa (eye worm) hypothetical protein 0.012 0.0198 0.0227
Trichomonas vaginalis calpain, putative 0.0229 0.0569 0.1063
Echinococcus granulosus epidermal growth factor receptor 0.0294 0.0792 0.0787
Echinococcus granulosus biogenic amine 5HT receptor 0.0349 0.098 0.0975
Loa Loa (eye worm) hypothetical protein 0.0079 0.0056 0.0065
Brugia malayi neuroendocrine convertase 1 precursor 0.1669 0.5484 0.628
Brugia malayi putative neuropeptide receptor 0.0349 0.098 0.1122
Schistosoma mansoni ubiquitin-specific peptidase 14 (C19 family) 0.0074 0.0041 0.0037
Trichomonas vaginalis cyclin B, putative 0.0077 0.005 0.0083
Echinococcus granulosus neuropeptide s receptor 0.0349 0.098 0.0975
Loa Loa (eye worm) hypothetical protein 0.0144 0.0278 0.0319
Trypanosoma cruzi major cysteine proteinase, putative 0.0198 0.0465 0.1685
Loa Loa (eye worm) hypothetical protein 0.262 0.8733 1
Echinococcus multilocularis proprotein convertase subtilisin:kexin type 5 0.1616 0.5304 0.5301
Echinococcus multilocularis neuropeptide receptor 0.0806 0.2539 0.2535
Onchocerca volvulus 0.0349 0.098 0.502
Echinococcus multilocularis cyclin 0.0077 0.005 0.0044
Schistosoma mansoni hypothetical protein 0.0068 0.002 0.0015
Entamoeba histolytica cysteine proteinase 2 0.0129 0.0228 0.1146
Trypanosoma brucei variant surface glycoprotein (VSG), putative 0.0274 0.0722 0.2624
Leishmania major hypothetical protein, unknown function 0.0692 0.2149 0.7855
Schistosoma mansoni Nep2 peptidase (M13 family) 0.0146 0.0287 0.0298
Loa Loa (eye worm) hypothetical protein 0.0166 0.0354 0.0405
Brugia malayi endochitinase 0.04 0.1154 0.1322
Loa Loa (eye worm) integrin alpha pat-2 0.0487 0.1451 0.1662
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0098 0.0122 0.1339
Onchocerca volvulus Putative endochitinase 0.04 0.1154 0.5917
Leishmania major trypanothione synthetase-like protein 0.0071 0.0029 0.0087
Brugia malayi Stress-activated protein kinase jnk-1 0.0236 0.0592 0.0678
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.036 0.1018 0.3712
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0067 0.0018 0.0021
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.051 0.1527 0.5577
Echinococcus multilocularis neuropeptide s receptor 0.0349 0.098 0.0975
Loa Loa (eye worm) neuropeptide F receptor 0.0349 0.098 0.1122
Loa Loa (eye worm) aminopeptidase N 0.0106 0.0151 0.0173
Trypanosoma cruzi cdc2-related kinase 3 0.0087 0.0084 0.0291
Plasmodium falciparum subtilisin-like protease 2 0.012 0.0198 0.2212
Echinococcus multilocularis calpain A 0.0289 0.0775 0.0769
Entamoeba histolytica hypothetical protein 0.0064 0.0008 0.0011
Leishmania major small myristoylated protein 4, putative 0.0652 0.2013 0.7356
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0131 0.0233 0.0834
Schistosoma mansoni calpain-7 (C02 family) 0.0368 0.1045 0.11
Loa Loa (eye worm) hypothetical protein 0.0633 0.1948 0.2231
Trypanosoma cruzi UDP-galactopyranose mutase 0.0098 0.0122 0.043
Schistosoma mansoni inhibitor of apoptosis (iap) domain family member 0.0217 0.0529 0.0553
Trypanosoma cruzi subtilisin peptidase 0.012 0.0198 0.0708
Loa Loa (eye worm) hypothetical protein 0.0079 0.0056 0.0065
Brugia malayi ubiquitin C-terminal hydrolase UCH-L5 0.0118 0.0191 0.0218
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0421 0.1224 0.4466
Loa Loa (eye worm) TK/EGFR protein kinase 0.0294 0.0792 0.0907
Loa Loa (eye worm) hypothetical protein 0.0219 0.0537 0.0614
Loa Loa (eye worm) hypothetical protein 0.0417 0.121 0.1386
Toxoplasma gondii subtilisin SUB4 0.012 0.0198 0.2499
Brugia malayi Serotonin receptor 0.0349 0.098 0.1122
Leishmania major trypanothione synthetase, putative 0.0071 0.0029 0.0087
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0082 0.0066 0.006
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0245 0.0623 0.1164
Echinococcus granulosus neuropeptide receptor A26 0.0349 0.098 0.0975
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0166 0.0354 0.0657
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0118 0.0191 0.0681
Echinococcus granulosus calpain 5 0.0289 0.0775 0.0769
Echinococcus multilocularis neuropeptides capa receptor 0.0349 0.098 0.0975
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0349 0.098 0.0975
Onchocerca volvulus 0.0362 0.1023 0.5239
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.038 0.1086 0.3958
Trypanosoma brucei pyroglutamyl-peptidase I, putative 0.045 0.1325 0.4834
Schistosoma mansoni amine GPCR 0.0349 0.098 0.1031
Toxoplasma gondii peptidase c13 family protein 0.0064 0.0006 0.0014
Echinococcus multilocularis g protein coupled receptor 0.0349 0.098 0.0975
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase 13, putative 0.0081 0.0064 0.0668
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0243 0.0618 0.2246
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0129 0.0228 0.042
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.012 0.0198 0.0363
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0503 0.1503 0.5489
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0349 0.098 0.0975
Brugia malayi cathepsin F-like cysteine proteinase 0.0079 0.0056 0.0065
Echinococcus multilocularis cysteine protease 0.0245 0.0623 0.0617
Schistosoma mansoni tripeptidyl-peptidase II (S08 family) 0.012 0.0198 0.0203
Trypanosoma cruzi CYC2-like cyclin, putative 0.0633 0.1948 0.712
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0243 0.0618 0.2246
Echinococcus granulosus dro:myosuppressin receptor 0.0349 0.098 0.0975
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0417 0.1211 0.442
Schistosoma mansoni biogenic amine (5HT) receptor 0.0349 0.098 0.1031
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.012 0.0198 0.0363
Echinococcus multilocularis neuroendocrine convertase 2 0.1669 0.5484 0.5481
Plasmodium vivax unspecified product 0.0079 0.0056 0.0603
Plasmodium falciparum cyclin 0.0318 0.0874 1
Trichomonas vaginalis conserved hypothetical protein 0.035 0.0982 0.1842
Echinococcus granulosus c-Jun N-terminal kinases 0.0236 0.0592 0.0587
Schistosoma mansoni alpha-1 adrenergic receptor 0.0349 0.098 0.1031
Loa Loa (eye worm) hypothetical protein 0.0349 0.098 0.1122
Trypanosoma brucei hypothetical protein, conserved 0.035 0.0982 0.3577
Loa Loa (eye worm) hypothetical protein 0.0082 0.0066 0.0076
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0426 0.1243 0.4534
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.012 0.0198 0.0363
Entamoeba histolytica peptidase, C54 family 0.0086 0.0081 0.0387
Echinococcus multilocularis oligomeric golgi complex subunit 3 0.0077 0.005 0.0044
Echinococcus multilocularis neuropeptide FF receptor 2 0.105 0.3372 0.3368
Echinococcus granulosus calpain 0.0289 0.0775 0.0769
Plasmodium vivax cyclin homologue, putative 0.0077 0.005 0.0526
Entamoeba histolytica peptidase, C54 family 0.0205 0.0487 0.2476
Loa Loa (eye worm) hypothetical protein 0.0079 0.0056 0.0065
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0274 0.0722 0.2627
Trypanosoma brucei glutathionylspermidine synthetase, putative 0.0071 0.0029 0.0083
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0174 0.0381 0.1378
Trichomonas vaginalis hypothetical protein 0.0544 0.1644 0.3092
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase UCHL3 0.0131 0.0233 0.2959
Loa Loa (eye worm) hypothetical protein 0.0324 0.0895 0.1025
Trypanosoma cruzi mitotic cyclin, putative 0.0077 0.005 0.0165
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0131 0.0233 0.0838
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.012 0.0198 0.0363
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0818 0.258 0.9435
Mycobacterium leprae PROBABLE MEMBRANE-ANCHORED MYCOSIN MYCP3 (SERINE PROTEASE) (SUBTILISIN-LIKE PROTEASE) (SUBTILASE-LIKE) (MYCOSIN-3) 0.012 0.0198 0.1156
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0664 0.2054 0.3867
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 5 0.0084 0.0074 0.0068
Echinococcus multilocularis cyclin dependent kinase 1 0.0087 0.0084 0.0078
Trypanosoma cruzi SUMO1/Ulp2, putative 0.0188 0.0431 0.1561
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0084 0.0074 0.0253
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0349 0.098 0.0975
Trypanosoma cruzi cysteine proteinase, putative 0.0129 0.0228 0.082
Onchocerca volvulus Cathepsin L homolog 0.0245 0.0623 0.3181
Echinococcus multilocularis integrin alpha ps 0.0142 0.0271 0.0266
Echinococcus multilocularis cyclin A3 4 0.0077 0.005 0.0044
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0349 0.098 0.0975
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0129 0.0228 0.042
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0274 0.0722 0.2624
Loa Loa (eye worm) CYL-1 protein 0.0077 0.005 0.0057
Mycobacterium ulcerans membrane-anchored mycosin MycP3 0.012 0.0198 0.0912
Brugia malayi Cyclin, N-terminal domain containing protein 0.0077 0.005 0.0057
Leishmania major CYC2-like cyclin, putative,cyclin 6, putative 0.0633 0.1948 0.712
Trichomonas vaginalis conserved hypothetical protein 0.012 0.0198 0.0363
Trypanosoma brucei glucosamine 6-phosphate n-acetyltransferase 0.0229 0.0569 0.2064
Trichomonas vaginalis cyclin A, putative 0.0077 0.005 0.0083
Onchocerca volvulus 0.0523 0.1572 0.8066
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase BAP1 0.0064 0.0008 0.0002
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0309 0.0844 0.3073
Brugia malayi sulfakinin receptor protein 0.0349 0.098 0.1122
Schistosoma mansoni ubiquitin-specific peptidase 46 (C19 family) 0.0076 0.0048 0.0044
Echinococcus multilocularis cyclin dependent kinase 1 0.0087 0.0084 0.0078
Mycobacterium ulcerans epoxide hydrolase EphA 0.0168 0.0363 0.2895
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0138 0.0258 0.0925
Loa Loa (eye worm) hypothetical protein 0.0176 0.0388 0.0445
Echinococcus multilocularis cyclins 0.0318 0.0874 0.0869
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0692 0.2149 0.7855
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0071 0.0029 0.0024
Echinococcus multilocularis Peptidase C54 0.0086 0.0081 0.0075
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0086 0.0081 0.0142
Brugia malayi peptidase family M13 containing protein 0.0071 0.0029 0.0033
Echinococcus multilocularis dnaJ subfamily B 0.2832 0.9455 0.9455
Entamoeba histolytica aminopeptidase, putative 0.0106 0.0151 0.0748
Schistosoma mansoni cathepsin F (C01 family) 0.0245 0.0623 0.0653
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase 14 0.0074 0.0041 0.0407
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0082 0.0066 0.0114
Echinococcus granulosus orexin receptor type 2 0.0349 0.098 0.0975
Trypanosoma brucei cdc2-related kinase 3 0.0087 0.0084 0.0287
Plasmodium vivax calpain, putative 0.0309 0.0844 1
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0245 0.0623 0.0713
Echinococcus granulosus rhodopsin orphan GPCR 0.0349 0.098 0.0975
Trypanosoma cruzi cyclin, putative 0.0633 0.1948 0.712
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0229 0.0569 0.1063
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0349 0.098 0.1031
Onchocerca volvulus 0.0349 0.098 0.502
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0349 0.098 0.1031
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0503 0.1503 0.5488
Echinococcus granulosus cyclins 0.0318 0.0874 0.0869
Echinococcus multilocularis epidermal growth factor receptor 0.0294 0.0792 0.0787
Echinococcus multilocularis rhodopsin orphan GPCR 0.0349 0.098 0.0975
Brugia malayi Cyclin, N-terminal domain containing protein 0.0077 0.005 0.0057
Onchocerca volvulus 0.0349 0.098 0.502
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0271 0.0713 0.2595
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0115 0.0181 0.0645
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0076 0.0048 0.0153
Echinococcus granulosus tachykinin peptides receptor 99D 0.0349 0.098 0.0975
Trypanosoma cruzi cysteine peptidase, Clan CD, family C13, putative 0.0064 0.0006 0.0004
Toxoplasma gondii subtilisin SUB5 0.012 0.0198 0.2499
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0245 0.0623 0.1164
Leishmania major otubain, putative,otubain cysteine peptidase, Clan CA, family C65, putative 0.009 0.0095 0.0329
Loa Loa (eye worm) hypothetical protein 0.0077 0.005 0.0057
Toxoplasma gondii UBA/TS-N domain-containing protein 0.0084 0.0074 0.0894
Leishmania major cyclin 0.0633 0.1948 0.712
Leishmania major hypothetical protein, conserved 0.0071 0.0029 0.0087
Entamoeba histolytica cysteine proteinase, putative 0.0245 0.0623 0.3174
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0245 0.0623 0.1164
Toxoplasma gondii sortilin, putative 0.0283 0.0753 0.9686
Trypanosoma cruzi serine peptidase, clan SB, family S8-like protein 0.012 0.0198 0.0708
Echinococcus granulosus cyclin k 0.0077 0.005 0.0044
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0349 0.098 0.1031
Loa Loa (eye worm) hypothetical protein 0.0349 0.098 0.1122
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0392 0.1128 0.4111
Mycobacterium ulcerans aminopeptidase N PepN 0.0106 0.0151 0.035
Brugia malayi Peptidase family C54 containing protein 0.0086 0.0081 0.0093
Echinococcus multilocularis tissue type plasminogen activator 0.0178 0.0397 0.0391
Echinococcus multilocularis cyclins 0.0318 0.0874 0.0869
Plasmodium falciparum cyclin 1 0.0077 0.005 0.0507
Loa Loa (eye worm) hypothetical protein 0.0349 0.098 0.1122
Loa Loa (eye worm) hypothetical protein 0.0349 0.098 0.1122
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0392 0.1128 0.4111
Loa Loa (eye worm) hypothetical protein 0.0349 0.098 0.1122
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0243 0.0618 0.2246
Brugia malayi Protein kinase domain containing protein 0.0178 0.0397 0.0454
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0082 0.0066 0.0199
Brugia malayi endoprotease bli-4 precursor 0.262 0.8733 1
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0106 0.0151 0.0145
Loa Loa (eye worm) hypothetical protein 0.0633 0.1948 0.2231
Schistosoma mansoni cathepsin F (C01 family) 0.0166 0.0354 0.0368
Schistosoma mansoni ubiquitin-specific peptidase 10 (C19 family) 0.0138 0.0258 0.0267
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.0289 0.0775 0.0769
Echinococcus multilocularis membrane bound transcription factor site 1 0.012 0.0198 0.0192
Trypanosoma brucei cysteine peptidase, putative 0.0595 0.1819 0.6646
Trichomonas vaginalis cyclin B, putative 0.0318 0.0874 0.1639
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0138 0.0258 0.0928
Brugia malayi G protein-coupled receptor F59B2.13 0.0349 0.098 0.1122
Trypanosoma cruzi small myristoylated protein 1-1 0.0437 0.128 0.4673
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.066 0.204 0.7454
Brugia malayi hypothetical protein 0.0349 0.098 0.1122
Toxoplasma gondii cyclin 4, putative 0.0077 0.005 0.0584
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0349 0.098 0.1031
Loa Loa (eye worm) hypothetical protein 0.009 0.0095 0.0108
Loa Loa (eye worm) hypothetical protein 0.0349 0.098 0.1122
Loa Loa (eye worm) hypothetical protein 0.0166 0.0354 0.0405
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0086 0.0081 0.0142
Schistosoma mansoni neuropeptide receptor 0.0349 0.098 0.1031
Brugia malayi Cyclin, N-terminal domain containing protein 0.0633 0.1948 0.2231
Echinococcus granulosus proprotein convertase subtilisin:kexin type 5 0.1616 0.5304 0.5301
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0082 0.0066 0.031
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0392 0.1128 0.4111
Onchocerca volvulus 0.0349 0.098 0.502
Schistosoma mansoni calpain-2 (C02 family) 0.0229 0.0569 0.0596
Trypanosoma cruzi metallo-peptidase, Clan MA(E) Family M1 0.0069 0.0023 0.0068
Brugia malayi Integrin beta pat-3 precursor 0.0324 0.0893 0.1022
Echinococcus granulosus oligomeric golgi complex subunit 3 0.0077 0.005 0.0044
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0349 0.098 0.0975
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0595 0.1819 0.6647
Schistosoma mansoni myosin xvIII 0.0349 0.098 0.1031
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0103 0.0141 0.0499
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0217 0.0529 0.0606
Trypanosoma brucei mitotic cyclin 0.0077 0.005 0.0161
Trichomonas vaginalis CMGC family protein kinase 0.0087 0.0084 0.0148
Trypanosoma cruzi cysteine peptidase, Clan CA, family C51, putative 0.0327 0.0904 0.3295
Chlamydia trachomatis protoporphyrinogen oxidase 0.0098 0.0122 0.5
Onchocerca volvulus Deterin homolog 0.0217 0.0529 0.27
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0271 0.0713 0.2595
Mycobacterium ulcerans hypothetical protein 0.0104 0.0142 0.0235
Schistosoma mansoni hypothetical protein 0.0069 0.0024 0.002
Onchocerca volvulus 0.0245 0.0623 0.3181
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0068 0.0021 0.0029
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.038 0.1086 0.3961
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0349 0.098 0.1031
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0349 0.098 0.1031
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0349 0.098 0.0975
Plasmodium vivax sortilin, putative 0.0283 0.0753 0.8925
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0349 0.098 0.1122
Brugia malayi Cyclin, N-terminal domain containing protein 0.0077 0.005 0.0057
Entamoeba histolytica cysteine protease, putative 0.0129 0.0228 0.1146
Trypanosoma cruzi cysteine peptidase inhibitor, putative 0.0245 0.0624 0.2268
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0245 0.0623 0.1164
Echinococcus granulosus ubiquitin specific peptidase c family 0.0138 0.0258 0.0252
Echinococcus granulosus cyclins 0.0318 0.0874 0.0869
Leishmania major cathepsin L-like protease 0.0245 0.0623 0.2263
Onchocerca volvulus 0.0349 0.098 0.502
Brugia malayi Serotonin receptor 0.0349 0.098 0.1122
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.0421 0.1224 0.4466
Trypanosoma cruzi cdc2-related kinase 3 0.0087 0.0084 0.0291
Entamoeba histolytica cysteine protease, putative 0.0129 0.0228 0.1146
Trichomonas vaginalis calpain, putative 0.0229 0.0569 0.1063
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 36 0.0067 0.0018 0.0012
Trichomonas vaginalis cyclin B3, putative 0.0077 0.005 0.0083
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0082 0.0066 0.006
Echinococcus multilocularis serotonin receptor 0.0349 0.098 0.0975
Trypanosoma cruzi hypothetical protein, conserved 0.035 0.0982 0.358
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0664 0.2054 0.3867
Entamoeba histolytica cysteine proteinase, putative 0.0129 0.0228 0.1146
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0082 0.0066 0.0064
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0683 0.2121 0.775
Brugia malayi Cyclin, N-terminal domain containing protein 0.0077 0.005 0.0057
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0086 0.0081 0.0142
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0129 0.0228 0.0236
Loa Loa (eye worm) cyclin domain-containing protein 0.0077 0.005 0.0057
Loa Loa (eye worm) hypothetical protein 0.105 0.3372 0.3861
Trypanosoma brucei inhibitor of cysteine peptidase 0.0245 0.0624 0.2265
Entamoeba histolytica cysteine protease, putative 0.0129 0.0228 0.1146
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0077 0.005 0.0507
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0081 0.0064 0.011
Leishmania major small myristoylated protein-1 0.0437 0.128 0.4673
Plasmodium vivax cyclin dependent kinase binding protein, putative 0.0077 0.005 0.0526
Trypanosoma brucei small myristoylated protein 1-1 0.0437 0.128 0.4671
Echinococcus granulosus rhodopsin orphan GPCR 0.0349 0.098 0.0975
Loa Loa (eye worm) cyclin C 0.0077 0.005 0.0057
Loa Loa (eye worm) hypothetical protein 0.0074 0.0041 0.0047
Echinococcus multilocularis aminopeptidase N 0.0362 0.1023 0.1017
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0081 0.0064 0.0073
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0349 0.098 0.0975
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0087 0.0084 0.1028
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0641 0.1976 0.7222
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0229 0.0569 0.1063
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 7 0.0081 0.0064 0.0058
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.0106 0.0151 0.0274
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0087 0.0084 0.0096
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0563 0.1709 0.6243
Schistosoma mansoni cytosol alanyl aminopeptidase (M01 family) 0.0106 0.0151 0.0154
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0349 0.098 0.0975
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0103 0.0141 0.0161
Echinococcus multilocularis G protein coupled receptor 139 0.0806 0.2539 0.2535
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0863 0.2735 1
Toxoplasma gondii subtilisin SUB11 0.012 0.0198 0.2499
Echinococcus granulosus g protein coupled receptor 0.0349 0.098 0.0975
Schistosoma mansoni hypothetical protein 0.0229 0.0569 0.0596
Echinococcus multilocularis sex peptide receptor 0.0349 0.098 0.0975
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0103 0.0141 0.0499
Schistosoma mansoni hypothetical protein 0.0349 0.098 0.1031
Echinococcus granulosus cyclin b3 0.0318 0.0874 0.0869
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0129 0.0228 0.082
Trichomonas vaginalis neuroendocrine convertase 2 precursor, putative 0.0544 0.1644 0.3092
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0079 0.0056 0.0065
Trypanosoma brucei Aminopeptidase M1, putative 0.0106 0.0151 0.0533
Echinococcus granulosus cysteine protease atg4b 0.0086 0.0081 0.0075
Trypanosoma cruzi glutathionylspermidine synthase, putative 0.0071 0.0029 0.0087
Echinococcus multilocularis neuropeptides capa receptor 0.0349 0.098 0.0975
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0563 0.1709 0.6243
Loa Loa (eye worm) cyclin domain-containing protein 0.0077 0.005 0.0057
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0863 0.2735 1
Brugia malayi Cathepsin L-like cysteine proteinase 0.0166 0.0354 0.0405
Leishmania major cathepsin L-like protease 0.0245 0.0623 0.2263
Echinococcus granulosus inhibitor of apoptosis protein 0.0217 0.0529 0.0523
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0074 0.0041 0.0471
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0245 0.0623 0.1164
Plasmodium falciparum calpain 0.0249 0.0638 0.7279
Onchocerca volvulus 0.0633 0.1948 1
Loa Loa (eye worm) hypothetical protein 0.0349 0.098 0.1122
Onchocerca volvulus 0.0245 0.0623 0.3181
Trichomonas vaginalis cyclins, putative 0.0633 0.1948 0.3667
Echinococcus granulosus peptidase s8 s53 subtilisin kexin sedolisin 0.012 0.0198 0.0192
Echinococcus granulosus serotonin receptor 0.0349 0.098 0.0975
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase BAP1 0.0064 0.0008 0.0002
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0349 0.098 0.1031
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 14 0.0081 0.0064 0.0191
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0115 0.0181 0.0645
Trypanosoma cruzi hypothetical protein, conserved 0.035 0.0982 0.358
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0863 0.2735 1
Brugia malayi Papain family cysteine protease containing protein 0.0129 0.0228 0.0262
Toxoplasma gondii cyclin dependent kinase binding protein 0.0077 0.005 0.0584
Echinococcus multilocularis cyclin dependent kinase 5 0.0087 0.0084 0.0078
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 12 0.0076 0.0048 0.0042
Entamoeba histolytica cysteine protease, putative 0.0245 0.0623 0.3174
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0417 0.1211 0.442
Echinococcus multilocularis fmrfamide receptor 0.0349 0.098 0.0975
Schistosoma mansoni adenoreceptor 0.0349 0.098 0.1031
Trypanosoma cruzi conserved protein 0.0454 0.1338 0.4883
Brugia malayi hypothetical protein 0.0077 0.005 0.0057
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase isozyme 0.0118 0.0191 0.0185
Schistosoma mansoni hypothetical protein 0.0349 0.098 0.1031
Leishmania major META domain containing protein 0.0281 0.0746 0.2715
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0349 0.098 0.1031
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0109 0.0158 0.0181
Leishmania major subtilisin-like serine peptidase 0.012 0.0198 0.0708
Brugia malayi Cyclin, N-terminal domain containing protein 0.0318 0.0874 0.1001
Loa Loa (eye worm) hypothetical protein 0.0749 0.2346 0.2686
Loa Loa (eye worm) zinc metallopeptidase 4 0.0071 0.0029 0.0033
Leishmania major cathepsin L-like protease 0.0245 0.0623 0.2263
Onchocerca volvulus 0.0166 0.0354 0.18
Echinococcus granulosus somatostatin receptor 0.0349 0.098 0.0975
Trypanosoma cruzi cysteine peptidase, Clan CA, family C51, putative 0.0327 0.0904 0.3295
Echinococcus granulosus rhodopsin orphan GPCR 0.0349 0.098 0.0975
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 0.0106 0.0151 0.0536
Entamoeba histolytica cyclin C, putative 0.0077 0.005 0.0227
Brugia malayi hypothetical protein 0.0349 0.098 0.1122
Giardia lamblia Kinase, CMGC CDK 0.0087 0.0084 0.0259
Leishmania major mitotic cyclin, putative 0.0077 0.005 0.0165
Schistosoma mansoni cyclins 0.0318 0.0874 0.0919
Trypanosoma cruzi cysteine peptidase, putative 0.0392 0.1128 0.4113
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0163 0.0345 0.1247
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0074 0.0041 0.0129
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 14 0.0074 0.0041 0.0116
Loa Loa (eye worm) peptidase family M1 containing protein 0.0293 0.0787 0.0901
Trypanosoma brucei mitotic cyclin 6 0.0633 0.1948 0.7119
Loa Loa (eye worm) cyclin domain-containing protein 0.0077 0.005 0.0057
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0652 0.2013 0.7356
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.036 0.1018 0.3709
Trypanosoma cruzi cysteine peptidase, Clan CA, family C51, putative 0.0327 0.0904 0.3295
Trichomonas vaginalis conserved hypothetical protein 0.0544 0.1644 0.3092
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 14 0.0074 0.0041 0.0035
Echinococcus multilocularis rhodopsin orphan GPCR 0.0349 0.098 0.0975
Echinococcus granulosus cyclins 0.0318 0.0874 0.0869
Trypanosoma cruzi cdc2-related kinase 1 0.0087 0.0084 0.0291
Loa Loa (eye worm) hypothetical protein 0.0181 0.0406 0.0465
Trypanosoma brucei Calpain-like protein CALP1.3 0.051 0.1527 0.5575
Loa Loa (eye worm) hypothetical protein 0.0315 0.0862 0.0987
Toxoplasma gondii subtilisin SUB8 0.012 0.0198 0.2499
Schistosoma mansoni hypothetical protein 0.0076 0.0046 0.0043
Trypanosoma brucei Calpain-like protein 1.2 0.066 0.204 0.7453
Echinococcus granulosus lysine specific histone demethylase 1A 0.0098 0.0122 0.0116
Trypanosoma cruzi trypanothione synthetase 0.0071 0.0029 0.0087
Leishmania major hypothetical protein, conserved 0.0281 0.0746 0.2715
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0074 0.0041 0.0133
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0087 0.0084 0.0096
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0106 0.0151 0.0145
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0243 0.0618 0.2243
Loa Loa (eye worm) endoprotease bli-4 0.262 0.8733 1
Loa Loa (eye worm) hypothetical protein 0.0749 0.2346 0.2686
Echinococcus multilocularis orexin receptor type 2 0.0349 0.098 0.0975
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.012 0.0198 0.0363
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0217 0.0529 0.0606
Schistosoma mansoni family C12 unassigned peptidase (C12 family) 0.0131 0.0233 0.0241
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0818 0.258 0.9435
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0074 0.0041 0.0133
Echinococcus granulosus neuropeptide Y receptor 0.0349 0.098 0.0975
Brugia malayi Dopamine receptor protein 2 0.0349 0.098 0.1122
Echinococcus multilocularis cysteine protease 0.0245 0.0623 0.0617
Trypanosoma cruzi cysteine peptidase, putative 0.0245 0.0623 0.2263
Loa Loa (eye worm) hypothetical protein 0.0219 0.0537 0.0614
Onchocerca volvulus 0.0217 0.0529 0.27
Leishmania major calpain-like protein, putative,cysteine peptidase, Clan CA, family C2, putative 0.0683 0.2121 0.775
Schistosoma mansoni Protoporphyrinogen oxidase chloroplast/mitochondrial precursor 0.0098 0.0122 0.0123
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0115 0.0181 0.033
Trypanosoma cruzi otubain cysteine peptidase, Clan CA, family C65, putative 0.009 0.0095 0.0329
Onchocerca volvulus 0.0245 0.0623 0.3181
Brugia malayi Cathepsin L-like precursor 0.0245 0.0623 0.0713
Onchocerca volvulus Putative endochitinase 0.04 0.1154 0.5917
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0563 0.1709 0.6243
Mycobacterium leprae PROBABLE PROLINE RICH MEMBRANE-ANCHORED MYCOSIN MYCP5 (SERINE PROTEASE) (SUBTILISIN-LIKE PROTEASE) (SUBTILASE-LIKE) (MYCOSIN-5) 0.012 0.0198 0.1156
Echinococcus granulosus allatostatin A receptor 0.0349 0.098 0.0975
Loa Loa (eye worm) hypothetical protein 0.0349 0.098 0.1122
Loa Loa (eye worm) hypothetical protein 0.0349 0.098 0.1122
Trypanosoma brucei amidase, putative 0.0071 0.0029 0.0083
Echinococcus multilocularis cyclin G2 0.0077 0.005 0.0044
Schistosoma mansoni biogenic amine receptor 0.0349 0.098 0.1031
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0563 0.1709 0.6243
Trichomonas vaginalis cyclin B, putative 0.0633 0.1948 0.3667
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0076 0.0048 0.0079
Echinococcus multilocularis neuropeptide Y receptor 0.0349 0.098 0.0975
Loa Loa (eye worm) ubiquitin C-terminal hydrolase UCH-L5 0.0118 0.0191 0.0218
Toxoplasma gondii hypothetical protein 0.0229 0.0569 0.7299
Onchocerca volvulus 0.0106 0.0151 0.0758
Toxoplasma gondii cathepsin B 0.0115 0.0181 0.2279
Echinococcus multilocularis cyclins 0.0318 0.0874 0.0869
Loa Loa (eye worm) cathepsin B 0.0115 0.0181 0.0207
Trypanosoma brucei metallo-peptidase, Clan MA(E) Family M1 0.0106 0.0151 0.0533
Brugia malayi Cathepsin L-like precursor 0.0245 0.0623 0.0713
Trichomonas vaginalis conserved hypothetical protein 0.012 0.0198 0.0363
Trichomonas vaginalis CMGC family protein kinase 0.0087 0.0084 0.0148
Echinococcus multilocularis calpain 0.0289 0.0775 0.0769
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0563 0.1709 0.6242
Schistosoma mansoni Mername-AA248 (C02 family) 0.0289 0.0775 0.0814
Giardia lamblia Cyclin fold protein 1, putative 0.0077 0.005 0.0145
Loa Loa (eye worm) hypothetical protein 0.0349 0.098 0.1122
Brugia malayi hypothetical protein 0.0098 0.0122 0.014
Echinococcus granulosus cyclin B 0.0633 0.1948 0.1944
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0349 0.098 0.1031
Echinococcus granulosus calpain A 0.0289 0.0775 0.0769
Trichomonas vaginalis cyclins, putative 0.0633 0.1948 0.3667
Loa Loa (eye worm) cuticular endochitinase 0.04 0.1154 0.1322
Brugia malayi calpain 5 0.0229 0.0569 0.0652
Schistosoma mansoni hypothetical protein 0.0178 0.0397 0.0414
Loa Loa (eye worm) hypothetical protein 0.0239 0.0604 0.0692
Brugia malayi Membrane-bound transcription factor site-1 protease precursor 0.012 0.0198 0.0227
Loa Loa (eye worm) hypothetical protein 0.0349 0.098 0.1122
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase isozyme 0.0131 0.0233 0.0228
Toxoplasma gondii cathepsin CPC2 0.023 0.0571 0.7329
Brugia malayi Subtilase family protein 0.012 0.0198 0.0227
Echinococcus multilocularis G1:S specific cyclin D1 0.0077 0.005 0.0044
Schistosoma mansoni family M13 non-peptidase homologue (M13 family) 0.0146 0.0287 0.0298
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.012 0.0198 0.0363
Schistosoma mansoni integrin alpha-ps 0.0074 0.004 0.0036
Echinococcus granulosus hypothetical protein 0.0349 0.098 0.0975
Entamoeba histolytica cell division protein kinase 2, putative 0.0087 0.0084 0.0404
Echinococcus multilocularis rhodopsin orphan GPCR 0.0349 0.098 0.0975
Trypanosoma cruzi cyclin 9, putative 0.0077 0.005 0.0165
Giardia lamblia Hypothetical protein 0.0318 0.0874 0.2864
Entamoeba histolytica cysteine protease, putative 0.0129 0.0228 0.1146
Trypanosoma cruzi hypothetical protein, conserved 0.0077 0.005 0.0165
Echinococcus granulosus cathepsin b 0.0115 0.0181 0.0175
Schistosoma mansoni amine GPCR 0.0349 0.098 0.1031
Schistosoma mansoni biogenic amine (5HT) receptor 0.0349 0.098 0.1031
Leishmania major hypothetical protein, conserved 0.0281 0.0746 0.2715
Loa Loa (eye worm) hypothetical protein 0.0217 0.0529 0.0606
Loa Loa (eye worm) hypothetical protein 0.0219 0.0537 0.0614
Leishmania major GPI-anchor transamidase subunit 8 (GPI8), putative 0.0064 0.0006 0.0004
Trichomonas vaginalis cyclin B, putative 0.0633 0.1948 0.3667
Loa Loa (eye worm) hypothetical protein 0.0349 0.098 0.1122
Brugia malayi hypothetical protein 0.0349 0.098 0.1122
Loa Loa (eye worm) hypothetical protein 0.0074 0.004 0.0045
Trypanosoma brucei cyclin dependent kinase-binding protein, putative 0.0077 0.005 0.0161
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 12 0.0076 0.0048 0.0042
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase isozyme 0.0131 0.0233 0.0228
Schistosoma mansoni hypothetical protein 0.0077 0.005 0.0047
Plasmodium vivax vivapain-2 0.0245 0.0623 0.7361
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0349 0.098 0.1122
Plasmodium vivax vivapain-1 0.0129 0.0228 0.2657
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.038 0.1086 0.3958
Trichomonas vaginalis conserved hypothetical protein 0.012 0.0198 0.0363
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0129 0.0228 0.0236
Entamoeba histolytica cysteine protease, putative 0.0129 0.0228 0.1146
Trichomonas vaginalis conserved hypothetical protein 0.012 0.0198 0.0363
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0349 0.098 0.502
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0245 0.0623 0.1164
Echinococcus granulosus cdk5 and abl1 enzyme substrate 1 0.0077 0.005 0.0044
Schistosoma mansoni hypothetical protein 0.0076 0.0046 0.0043
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0664 0.2054 0.3867
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.012 0.0198 0.0363
Trichomonas vaginalis conserved hypothetical protein 0.0077 0.005 0.0083
Brugia malayi hypothetical protein 0.0349 0.098 0.1122
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0392 0.1128 0.4111
Onchocerca volvulus 0.0245 0.0623 0.3181
Trypanosoma cruzi otubain cysteine peptidase, Clan CA, family C65, putative 0.009 0.0095 0.0329
Loa Loa (eye worm) hypothetical protein 0.029 0.0778 0.0891
Loa Loa (eye worm) hypothetical protein 0.0064 0.0006 0.0007
Echinococcus granulosus cyclin dependent kinase 5 0.0087 0.0084 0.0078
Echinococcus granulosus tissue type plasminogen activator 0.0178 0.0397 0.0391
Trichomonas vaginalis Clan CA, family C12, ubiquitin hydrolase-like cysteine peptidase 0.0131 0.0233 0.043
Toxoplasma gondii subtilisin SUB9 0.012 0.0198 0.2499
Leishmania major SUMO1/Ulp2, putative,cysteine peptidase, Clan CA, family C48, putative 0.0188 0.0431 0.1561
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0349 0.098 0.1031
Brugia malayi Cyclin C 0.0077 0.005 0.0057
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0109 0.0158 0.0181
Plasmodium falciparum cysteine proteinase falcipain 1 0.0129 0.0228 0.2564
Schistosoma mansoni ubiquitin-specific peptidase 7 (C19 family) 0.0103 0.0141 0.0143
Echinococcus granulosus baculoviral IAP repeat containing protein 0.0217 0.0529 0.0523
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0221 0.0542 0.1966
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0349 0.098 0.1031
Loa Loa (eye worm) hypothetical protein 0.0086 0.0081 0.0093
Trichomonas vaginalis cyclins, putative 0.0633 0.1948 0.3667
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0086 0.0081 0.0142
Loa Loa (eye worm) hypothetical protein 0.0349 0.098 0.1122
Trypanosoma brucei META domain/Domain of unknown function (DUF1935), putative 0.0281 0.0746 0.2712
Echinococcus granulosus endothelin converting enzyme 1 0.029 0.0778 0.0772
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0106 0.0151 0.0145
Echinococcus granulosus neuropeptide receptor 0.0806 0.2539 0.2535
Echinococcus granulosus Ubiquitin thioesterase otubain protein 0.009 0.0095 0.0089
Entamoeba histolytica hypothetical protein 0.0077 0.005 0.0227
Entamoeba histolytica cysteine protease, putative 0.0129 0.0228 0.1146
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0081 0.0064 0.0073
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.1616 0.5304 1
Giardia lamblia Kinase, CMGC CDK 0.0087 0.0084 0.0259
Trypanosoma cruzi hypothetical protein, conserved 0.0281 0.0746 0.2715
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0082 0.0066 0.006
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0274 0.0722 0.2624
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0349 0.098 0.0975
Giardia lamblia Hypothetical protein 0.0077 0.005 0.0145
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.0106 0.0151 0.0274
Brugia malayi hypothetical protein 0.0349 0.098 0.1122
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0245 0.0623 0.1164
Giardia lamblia Cyclin A 0.0318 0.0874 0.2864
Schistosoma mansoni neuropeptide receptor 0.0806 0.2539 0.2681
Plasmodium vivax protein kinase Crk2 0.0087 0.0084 0.0936
Loa Loa (eye worm) hypothetical protein 0.0069 0.0023 0.0027
Echinococcus granulosus dnaJ subfamily B 0.2832 0.9455 0.9455
Schistosoma mansoni serine/threonine protein kinase 0.0087 0.0084 0.0083
Trichomonas vaginalis conserved hypothetical protein 0.0229 0.0569 0.1063
Echinococcus multilocularis cyclins 0.0318 0.0874 0.0869
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0349 0.098 0.1031
Onchocerca volvulus Cathepsin L homolog 0.0245 0.0623 0.3181
Toxoplasma gondii histone lysine-specific demethylase 0.0098 0.0122 0.1518
Trypanosoma brucei Domain of unknown function (DUF1935), putative 0.0281 0.0746 0.2712
Brugia malayi cell division control protein 2 homolog 0.0087 0.0084 0.0096
Trypanosoma brucei calpain-like protein, putative 0.0309 0.0844 0.307
Leishmania major cathepsin L-like protease 0.0245 0.0623 0.2263
Mycobacterium tuberculosis Possible chitinase 0.0341 0.0953 1
Trypanosoma cruzi Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative 0.0243 0.0618 0.2246
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0426 0.1243 0.4534
Loa Loa (eye worm) hypothetical protein 0.0178 0.0397 0.0454
Trichomonas vaginalis conserved hypothetical protein 0.0544 0.1644 0.3092
Echinococcus multilocularis lysine specific histone demethylase 1A 0.0482 0.1433 0.1428
Loa Loa (eye worm) melatonin receptor type 1A 0.0349 0.098 0.1122
Trypanosoma brucei serine peptidase, clan SB, family S8-like protein 0.012 0.0198 0.0704
Schistosoma mansoni inhibitor of apoptosis protein 0.0217 0.0529 0.0553
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 5 0.0079 0.0057 0.0051
Trypanosoma brucei calpain, putative 0.0503 0.1503 0.5488
Echinococcus granulosus integrin alpha 3 0.0242 0.0615 0.0609
Entamoeba histolytica cysteine proteinase, putative 0.0129 0.0228 0.1146
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0086 0.0081 0.0142
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0863 0.2735 1
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0229 0.0569 0.1063
Brugia malayi Cathepsin L-like precursor 0.0245 0.0623 0.0713
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0417 0.121 0.1274
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0309 0.0844 0.3073
Loa Loa (eye worm) hypothetical protein 0.0482 0.1433 0.1641
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0067 0.0018 0.0049
Schistosoma mansoni opsin-like receptor 0.0349 0.098 0.1031
Loa Loa (eye worm) hypothetical protein 0.1005 0.3217 0.3684
Toxoplasma gondii subtilisin SUB12 0.0178 0.0397 0.5075
Brugia malayi calpain family protein 1 0.0289 0.0775 0.0887
Trypanosoma cruzi AUT2/APG4/ATG4 cysteine peptidase, putative 0.0086 0.0081 0.0279
Loa Loa (eye worm) hypothetical protein 0.0349 0.098 0.1122
Trypanosoma brucei cdc2-related kinase 1 0.0087 0.0084 0.0287
Trypanosoma cruzi cysteine peptidase, Clan CA, family C51, putative 0.0327 0.0904 0.3295
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0245 0.0623 0.1164
Trichomonas vaginalis conserved hypothetical protein 0.0318 0.0874 0.1639
Trypanosoma cruzi trypanothione synthetase, putative 0.0071 0.0029 0.0087
Echinococcus granulosus calpain 7 C02 family 0.0322 0.0888 0.0883
Loa Loa (eye worm) hypothetical protein 0.0289 0.0775 0.0887
Entamoeba histolytica cysteine protease, putative 0.0129 0.0228 0.1146
Trypanosoma brucei trypanothione synthetase 0.0071 0.0029 0.0083
Onchocerca volvulus Cyclin L homolog 0.0077 0.005 0.0236
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0314 0.0859 0.3129
Schistosoma mansoni amine oxidase 0.0098 0.0122 0.0123
Echinococcus granulosus integrin beta 2 0.024 0.0606 0.0601
Leishmania major hypothetical protein, conserved 0.035 0.0982 0.358
Plasmodium vivax vivapain-3 0.0129 0.0228 0.2657
Echinococcus multilocularis rhodopsin orphan GPCR 0.0349 0.098 0.0975
Leishmania major chitinase 0.04 0.1154 0.4212
Loa Loa (eye worm) hypothetical protein 0.0349 0.098 0.1122
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0486 0.1448 0.5288
Brugia malayi Peptidase family M1 containing protein 0.0362 0.1023 0.1171
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0486 0.1448 0.5286
Entamoeba histolytica cysteine proteinase, putative 0.0129 0.0228 0.1146
Loa Loa (eye worm) hypothetical protein 0.0349 0.098 0.1122
Echinococcus granulosus integrin alpha ps 0.0142 0.0271 0.0266
Echinococcus multilocularis cyclin B 0.0633 0.1948 0.1944
Mycobacterium tuberculosis Probable membrane-anchored mycosin MycP4 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-4) 0.012 0.0198 0.0912
Plasmodium falciparum subtilisin-like protease 1 0.012 0.0198 0.2212
Loa Loa (eye worm) fibroinase 0.0245 0.0623 0.0713
Loa Loa (eye worm) calpain 0.0322 0.0888 0.1017
Trichomonas vaginalis conserved hypothetical protein 0.0082 0.0066 0.0114
Mycobacterium leprae Possible secreted protease 0.012 0.0198 0.1156
Schistosoma mansoni cyclin k 0.0077 0.005 0.0047
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0595 0.1819 0.6647
Brugia malayi SWIRM domain containing protein 0.0523 0.1572 0.18
Loa Loa (eye worm) hypothetical protein 0.0131 0.0233 0.0267
Brugia malayi Cyclin, N-terminal domain containing protein 0.0077 0.005 0.0057
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0349 0.098 0.0975
Toxoplasma gondii subtilisin SUB10 0.012 0.0198 0.2499
Echinococcus granulosus neuropeptides capa receptor 0.0349 0.098 0.0975
Echinococcus multilocularis fmrfamide receptor 0.0349 0.098 0.0975
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.029 0.0778 0.0817
Trypanosoma cruzi metallo-peptidase, clan MA(E), family M1, putative 0.0106 0.0151 0.0536
Brugia malayi hypothetical protein 0.0349 0.098 0.1122
Trypanosoma brucei CHAP domain containing protein, putative 0.0071 0.0029 0.0083
Onchocerca volvulus 0.0349 0.098 0.502
Loa Loa (eye worm) hypothetical protein 0.0349 0.098 0.1122
Onchocerca volvulus 0.0349 0.098 0.502
Schistosoma mansoni amine GPCR 0.0349 0.098 0.1031
Leishmania major cathepsin L-like protease 0.0392 0.1128 0.4113
Echinococcus multilocularis 0.0098 0.0122 0.0116
Schistosoma mansoni biogenic amine receptor 0.0349 0.098 0.1031
Echinococcus granulosus cathepsin b 0.0115 0.0181 0.0175
Echinococcus multilocularis sortilin 0.0283 0.0753 0.0748
Echinococcus granulosus cyclins 0.0318 0.0874 0.0869
Trichomonas vaginalis hypothetical protein 0.0229 0.0569 0.1063
Loa Loa (eye worm) hypothetical protein 0.0417 0.121 0.1386
Schistosoma mansoni subfamily S8B non-peptidase homologue (S08 family) 0.0664 0.2054 0.2168
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0349 0.098 0.1031
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0563 0.1709 0.6243
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase 13, putative 0.0081 0.0064 0.0693
Onchocerca volvulus 0.0349 0.098 0.502
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase, putative 0.0118 0.0191 0.0951
Schistosoma mansoni Lysine-specific histone demethylase 1 0.0482 0.1433 0.151
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 20 0.0109 0.0158 0.0153
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0082 0.0066 0.0225
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0664 0.2054 0.3867
Onchocerca volvulus Putative endochitinase 0.04 0.1154 0.5917
Trypanosoma brucei trypanothione synthetase, putative 0.0071 0.0029 0.0083
Trichomonas vaginalis calpain, putative 0.0229 0.0569 0.1063
Schistosoma mansoni opsin-like receptor 0.0349 0.098 0.1031
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0082 0.0066 0.0064
Echinococcus multilocularis g protein coupled receptor 0.0349 0.098 0.0975
Brugia malayi Cyclin, N-terminal domain containing protein 0.0077 0.005 0.0057
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0392 0.1128 0.4111
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0106 0.0151 0.0145
Mycobacterium leprae probable zinc metalloprotease 0.029 0.0778 1
Brugia malayi AKH receptor 0.0349 0.098 0.1122
Schistosoma mansoni biogenic amine receptor 0.0349 0.098 0.1031
Leishmania major calpain protease-like protein 0.0262 0.0682 0.2482
Trypanosoma cruzi cdc2-related kinase 1 0.0087 0.0084 0.0291
Schistosoma mansoni otubain-1 (C65 family) 0.009 0.0095 0.0094
Schistosoma mansoni hypothetical protein 0.0076 0.0046 0.0043
Brugia malayi cathepsin L-like precursor 0.0166 0.0354 0.0405
Trypanosoma cruzi cyclin 6, putative 0.0633 0.1948 0.712
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0626 0.1925 0.7035
Trichomonas vaginalis cyclins, putative 0.0318 0.0874 0.1639
Trypanosoma brucei SUMO1/Ulp2, putative 0.0188 0.0431 0.1558
Trypanosoma cruzi cysteine peptidase inhibitor 0.0245 0.0624 0.2268
Trypanosoma cruzi cysteine peptidase, Clan CA, family C19, putative 0.0079 0.0057 0.0192
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0082 0.0066 0.0114
Trypanosoma brucei Small kinetoplastid calpain-related protein 1-4 0.0588 0.1795 0.6558
Loa Loa (eye worm) G-protein coupled receptor 0.0349 0.098 0.1122
Trichomonas vaginalis cyclin B, putative 0.0633 0.1948 0.3667
Echinococcus granulosus alpha 1A adrenergic receptor 0.0349 0.098 0.0975
Onchocerca volvulus Protein CNPPD1 homolog 0.0077 0.005 0.0236
Mycobacterium ulcerans chitinase/cellulase 0.0341 0.0953 1
Trypanosoma cruzi cysteine proteinase, putative 0.0129 0.0228 0.082
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0221 0.0542 0.1963
Mycobacterium tuberculosis Probable proline rich membrane-anchored mycosin MycP5 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-5) 0.012 0.0198 0.0912
Echinococcus multilocularis cyclin dependent kinase 0.0087 0.0084 0.0078
Trypanosoma cruzi cysteine peptidase, putative 0.0392 0.1128 0.4113
Echinococcus multilocularis integrin alpha ps 0.0142 0.0271 0.0266
Echinococcus granulosus g protein coupled receptor 0.0349 0.098 0.0975
Plasmodium falciparum protoporphyrinogen oxidase 0.0098 0.0122 0.1339
Schistosoma mansoni ubiquitinyl hydrolase-BAP1 (C12 family) 0.0064 0.0008 0.0002
Loa Loa (eye worm) hypothetical protein 0.0349 0.098 0.1122
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0274 0.0722 0.2624
Leishmania major calpain family cysteine protease-like protein 0.0581 0.1773 0.6476
Trypanosoma brucei RNA helicase, putative 0.0308 0.084 0.3058
Onchocerca volvulus Cathepsin F homolog 0.0245 0.0623 0.3181
Trichomonas vaginalis conserved hypothetical protein 0.0544 0.1644 0.3092
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.012 0.0198 0.0363
Giardia lamblia Cyclin B-like protein 0.0077 0.005 0.0145
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0245 0.0623 0.1164
Entamoeba histolytica cysteine protease, putative 0.0129 0.0228 0.1146
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0082 0.0066 0.0225
Brugia malayi cathepsin B-like cysteine proteinase 0.0115 0.0181 0.0207
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0146 0.0287 0.0298
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0087 0.0084 0.0291
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0109 0.0158 0.0562
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0146 0.0287 0.0298
Trichomonas vaginalis CMGC family protein kinase 0.0087 0.0084 0.0148
Plasmodium vivax unspecified product 0.0129 0.0228 0.2657
Trypanosoma brucei cytoskeleton-associated protein CAP5.5, putative 0.0595 0.1819 0.6646
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0349 0.098 0.1031
Echinococcus multilocularis Ubiquitin thioesterase otubain protein 0.009 0.0095 0.0089
Trypanosoma cruzi Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative 0.0076 0.0048 0.0157
Onchocerca volvulus 0.0361 0.102 0.5224
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.012 0.0198 0.0363
Echinococcus multilocularis cyclin t1 0.0077 0.005 0.0044
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0245 0.0623 0.1164
Schistosoma mansoni neuropeptide f receptor 76f 0.0349 0.098 0.1031
Loa Loa (eye worm) hypothetical protein 0.0349 0.098 0.1122
Loa Loa (eye worm) hypothetical protein 0.0482 0.1433 0.1641
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0245 0.0623 0.1164
Brugia malayi proprotein convertase 2 0.1669 0.5484 0.628
Brugia malayi follicle stimulating hormone receptor 0.0349 0.098 0.1122
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0166 0.0354 0.0657
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0129 0.0228 0.0236
Echinococcus multilocularis cyclins 0.0318 0.0874 0.0869
Loa Loa (eye worm) hypothetical protein 0.0069 0.0023 0.0027
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 20 0.0109 0.0158 0.0153
Echinococcus granulosus membrane bound transcription factor site 1 0.012 0.0198 0.0192
Trypanosoma cruzi subtilisin-like serine peptidase, putative 0.012 0.0198 0.0708
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0626 0.1925 0.7035
Toxoplasma gondii hypothetical protein 0.0077 0.005 0.0584
Brugia malayi Cathepsin L-like precursor 0.0079 0.0056 0.0065
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0103 0.0141 0.0495
Echinococcus granulosus neuroendocrine convertase 2 0.1669 0.5484 0.5481
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.051 0.1527 0.5577
Echinococcus granulosus rhodopsin orphan GPCR 0.0349 0.098 0.0975
Loa Loa (eye worm) hypothetical protein 0.0074 0.0041 0.0047
Brugia malayi Hypothetical zinc metalloproteinase T16A9.4 0.029 0.0778 0.0891
Echinococcus multilocularis neuropeptide Y receptor 0.0349 0.098 0.0975
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0349 0.098 0.1031
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0245 0.0623 0.1164
Trypanosoma cruzi cysteine peptidase, Clan CA, family C51, putative 0.0327 0.0904 0.3295
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0417 0.121 0.1274
Loa Loa (eye worm) hypothetical protein 0.0255 0.0659 0.0755
Brugia malayi Dopamine receptor 0.0349 0.098 0.1122
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0236 0.0592 0.0678
Trypanosoma brucei subtilisin peptidase 0.012 0.0198 0.0704
Schistosoma mansoni amine oxidase 0.0098 0.0122 0.0123
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0082 0.0066 0.0225
Loa Loa (eye worm) hypothetical protein 0.0349 0.098 0.1122
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0349 0.098 0.0975
Brugia malayi amine oxidase, flavin-containing family protein 0.0139 0.0261 0.0299
Echinococcus multilocularis serotonin receptor 0.0349 0.098 0.0975
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0392 0.1128 0.4111
Loa Loa (eye worm) hypothetical protein 0.0214 0.0519 0.0595
Loa Loa (eye worm) hypothetical protein 0.0115 0.0181 0.0207
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0074 0.0041 0.0047
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0349 0.098 0.1031
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.066 0.204 0.7454
Schistosoma mansoni opsin-like receptor 0.0349 0.098 0.1031
Echinococcus granulosus tm gpcr rhodopsin 0.0349 0.098 0.0975
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0074 0.0041 0.0067
Schistosoma mansoni serine-type protease inhibitor 0.0429 0.1252 0.1319
Loa Loa (eye worm) TK/ROR protein kinase 0.0178 0.0397 0.0454
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase family 2, putative 0.0083 0.0072 0.0789
Loa Loa (eye worm) hypothetical protein 0.0349 0.098 0.1122
Echinococcus granulosus sortilin 0.0283 0.0753 0.0748
Schistosoma mansoni amine GPCR 0.0349 0.098 0.1031
Giardia lamblia Cathepsin B precursor 0.0115 0.0181 0.0578
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0245 0.0623 0.0713
Toxoplasma gondii ubiquitin thioesterase otubain-like family protein 0.009 0.0095 0.1163
Echinococcus granulosus cathepsin L 0.0129 0.0228 0.0223
Brugia malayi Cathepsin L-like precursor 0.0245 0.0623 0.0713
Schistosoma mansoni proteasome subunit alpha 1 (T01 family) 0.0077 0.005 0.0047
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.012 0.0198 0.0363
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0426 0.1243 0.4532
Onchocerca volvulus 0.0349 0.098 0.502
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0115 0.0181 0.0185
Echinococcus multilocularis cathepsin L cysteine protease 0.0245 0.0623 0.0617
Loa Loa (eye worm) hypothetical protein 0.0098 0.0122 0.014
Trypanosoma cruzi cruzipain precursor, putative 0.0392 0.1128 0.4113
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.023 0.0571 0.675
Trypanosoma brucei Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative 0.0243 0.0618 0.2243
Brugia malayi Cathepsin L-like precursor 0.0245 0.0623 0.0713
Echinococcus granulosus cyclin A3 4 0.0077 0.005 0.0044
Echinococcus granulosus calpain A 0.0289 0.0775 0.0769
Trichomonas vaginalis cyclins, putative 0.0633 0.1948 0.3667
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0349 0.098 0.1031
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase, family 1 protein 0.0118 0.0191 0.2404
Trypanosoma cruzi small myristoylated protein 1-2 0.0437 0.128 0.4673
Trypanosoma cruzi Domain of unknown function (DUF1935), putative 0.0281 0.0746 0.2715
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0245 0.0623 0.7103
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0074 0.0041 0.0133
Leishmania major cathepsin L-like protease 0.0245 0.0623 0.2263
Trypanosoma cruzi cysteine peptidase, putative 0.0392 0.1128 0.4113
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0349 0.098 0.1122
Schistosoma mansoni Cyclin fold protein 0.0077 0.005 0.0047
Loa Loa (eye worm) hypothetical protein 0.0214 0.0519 0.0595
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0087 0.0084 0.0078
Trichomonas vaginalis conserved hypothetical protein 0.0077 0.005 0.0083
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0163 0.0345 0.1247
Echinococcus granulosus g protein coupled receptor 0.0349 0.098 0.0975
Brugia malayi ubiquitin specific protease 14 0.0074 0.0041 0.0047
Trichomonas vaginalis conserved hypothetical protein 0.012 0.0198 0.0363
Entamoeba histolytica cysteine proteinase, putative 0.0166 0.0354 0.1791
Trypanosoma brucei cysteine peptidase, Clan CA, family C54, putative 0.0205 0.0487 0.1762
Onchocerca volvulus 0.0349 0.098 0.502
Echinococcus granulosus cathepsin l cysteine peptidase 0.0245 0.0623 0.0617
Brugia malayi Papain family cysteine protease containing protein 0.0245 0.0623 0.0713
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0115 0.0181 0.0185
Entamoeba histolytica cysteine proteinase, putative 0.0129 0.0228 0.1146
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.023 0.0571 0.6513
Toxoplasma gondii histone lysine-specific demethylase LSD1/BHC110/KDMA1A 0.0098 0.0122 0.1518
Schistosoma mansoni growth hormone secretagogue receptor 0.0349 0.098 0.1031
Leishmania major receptor-type adenylate cyclase a-like protein 0.0281 0.0746 0.2715
Loa Loa (eye worm) cyclin domain-containing protein 0.0318 0.0874 0.1001
Echinococcus multilocularis 0.2077 0.6877 0.6875
Trichomonas vaginalis cyclins, putative 0.0077 0.005 0.0083
Loa Loa (eye worm) hypothetical protein 0.0349 0.098 0.1122
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.2991 1 1
Loa Loa (eye worm) microfilarial chitinase 0.0341 0.0953 0.1091
Echinococcus multilocularis calpain family protein 1, d 0.0229 0.0569 0.0563
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.0115 0.0181 0.0185
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0087 0.0084 0.0096
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0392 0.1128 0.4111
Echinococcus granulosus tm gpcr rhodopsin 0.0349 0.098 0.0975
Schistosoma mansoni site-1 peptidase (S08 family) 0.012 0.0198 0.0203
Echinococcus multilocularis g-protein coupled receptor 0.0349 0.098 0.0975
Brugia malayi hypothetical protein 0.0349 0.098 0.1122
Echinococcus granulosus neuropeptide receptor 0.0349 0.098 0.0975
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0349 0.098 0.1122
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0349 0.098 0.1122
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 7 0.0103 0.0141 0.0135
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.012 0.0198 0.0363
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0068 0.0021 0.0029
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.0289 0.0775 0.0769
Entamoeba histolytica cysteine protease, putative 0.0129 0.0228 0.1146
Echinococcus multilocularis rhodopsin orphan GPCR 0.0349 0.098 0.0975
Schistosoma mansoni hypothetical protein 0.0217 0.0529 0.0553
Brugia malayi Papain family cysteine protease containing protein 0.0129 0.0228 0.0262
Echinococcus multilocularis Cyclin L1 0.0077 0.005 0.0044
Loa Loa (eye worm) neuropeptide F receptor 0.0349 0.098 0.1122
Trichomonas vaginalis conserved hypothetical protein 0.0544 0.1644 0.3092
Trypanosoma cruzi aminopeptidase, putative 0.0106 0.0151 0.0536
Leishmania major trypanothione synthetase, putative 0.0071 0.0029 0.0087
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.012 0.0198 0.0363
Trypanosoma brucei cysteine peptidase C (CPC) 0.0115 0.0181 0.0642
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0289 0.0775 0.0814
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0245 0.0623 0.1164
Plasmodium vivax lysine-specific histone demethylase 1, putative 0.0098 0.0122 0.1387
Trypanosoma cruzi mitotic cyclin, putative 0.0077 0.005 0.0165
Leishmania major pyroglutamyl-peptidase I (C15 family) 0.045 0.1325 0.4837
Trypanosoma cruzi unspecified product 0.0437 0.128 0.4673
Loa Loa (eye worm) hypothetical protein 0.0349 0.098 0.1122
Brugia malayi G protein-coupled receptor 0.0349 0.098 0.1122
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0076 0.0048 0.0157
Echinococcus multilocularis cyclin y 0.0077 0.005 0.0044
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0863 0.2735 1
Toxoplasma gondii peptidase family M13 protein 0.029 0.0778 1
Loa Loa (eye worm) hypothetical protein 0.0349 0.098 0.1122
Brugia malayi calpain 7 0.0322 0.0888 0.1017
Schistosoma mansoni serine-type protease inhibitor 0.0429 0.1252 0.1319
Trypanosoma brucei Small kinetoplastid calpain-related protein 1-5 0.0281 0.0746 0.2712
Leishmania major cathepsin L-like protease 0.0392 0.1128 0.4113
Trichomonas vaginalis conserved hypothetical protein 0.0077 0.005 0.0083
Toxoplasma gondii calpain family cysteine protease domain-containing protein 0.0249 0.0638 0.8189
Trypanosoma brucei META domain/Domain of unknown function (DUF1935), putative 0.0281 0.0746 0.2712
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0245 0.0623 0.1164
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0349 0.098 0.0975
Onchocerca volvulus 0.0349 0.098 0.502
Toxoplasma gondii subtilisin SUB7 0.012 0.0198 0.2499
Plasmodium vivax subtilisin-like serine protease, putative 0.012 0.0198 0.2293
Mycobacterium tuberculosis Probable membrane-anchored mycosin MycP3 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-3) 0.012 0.0198 0.0912
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0106 0.0151 0.0145
Entamoeba histolytica cysteine protease inhibitor 1 (EhICP1) 0.0245 0.0624 0.3182
Plasmodium vivax hypothetical protein, conserved 0.0067 0.0018 0.0146
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0087 0.0084 0.0291
Echinococcus granulosus peptide allatostatin:somatostatin 0.0349 0.098 0.0975
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0245 0.0623 0.1164
Entamoeba histolytica cyclin, putative 0.0633 0.1948 1
Trypanosoma brucei conserved protein 0.0225 0.0556 0.2018
Leishmania major aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 0.0106 0.0151 0.0536
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 7 0.0103 0.0141 0.0135
Trichomonas vaginalis cyclin D, putative 0.0318 0.0874 0.1639
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0289 0.0775 0.0814
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0349 0.098 0.0975
Echinococcus multilocularis inhibitor of apoptosis protein 0.0217 0.0529 0.0523
Echinococcus multilocularis neuropeptide receptor A26 0.0349 0.098 0.0975
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0245 0.0623 0.1164
Loa Loa (eye worm) hypothetical protein 0.0349 0.098 0.1122
Loa Loa (eye worm) hypothetical protein 0.0214 0.0519 0.0595
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0103 0.0141 0.0161
Trichomonas vaginalis leucine-rich repeat protein, BspA family 0.0544 0.1644 0.3092
Echinococcus multilocularis cyclin y 0.0077 0.005 0.0044
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0349 0.098 0.1031
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0103 0.0141 0.0255
Entamoeba histolytica cyclin family protein 0.0318 0.0874 0.447
Echinococcus granulosus rhodopsin orphan GPCR 0.0349 0.098 0.0975
Mycobacterium tuberculosis Probable zinc metalloprotease Zmp1 0.029 0.0778 0.789
Onchocerca volvulus 0.0417 0.121 0.6203
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0349 0.098 0.1031
Schistosoma mansoni intracisternal A-particle retropepsin (A02 family) 0.2574 0.8575 0.9068
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0068 0.0021 0.0029
Trypanosoma cruzi pyroglutamyl-peptidase I, putative 0.045 0.1325 0.4837
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0243 0.0618 0.2246

Activities

Activity type Activity value Assay description Source Reference
GI50 (functional) = 5.57 Cytotoxicity against human CCRF-CEM cells after 48 hrs by SRB assay ChEMBL. 22892346

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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