Detailed information for compound 1783245

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 267.322 | Formula: C17H17NO2
  • H donors: 1 H acceptors: 1 LogP: 2.99 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C1CCc2c(N1)ccc(c2)OCCc1ccccc1
  • InChi: 1S/C17H17NO2/c19-17-9-6-14-12-15(7-8-16(14)18-17)20-11-10-13-4-2-1-3-5-13/h1-5,7-8,12H,6,9-11H2,(H,18,19)
  • InChiKey: MMJBZBLQNNAVCU-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens monoamine oxidase B Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Mycobacterium tuberculosis Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) Get druggable targets OG5_130722 All targets in OG5_130722
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH Get druggable targets OG5_130722 All targets in OG5_130722
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH Get druggable targets OG5_130722 All targets in OG5_130722
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Brugia malayi amine oxidase, flavin-containing family protein monoamine oxidase B 520 aa 462 aa 19.7 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni nuclear hormone receptor 0.0014 0.0002 0.0002
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.013 0.0589 0.1978
Loa Loa (eye worm) glutaminase 2 0.0269 0.1299 0.1298
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0032 0.0093 0.029
Leishmania major diacylglycerol kinase, putative 0.0077 0.0322 0.1069
Echinococcus multilocularis zinc finger protein 0.0047 0.0167 0.0166
Loa Loa (eye worm) hypothetical protein 0.198 1 1
Toxoplasma gondii peptidylprolyl isomerase 0.0032 0.0093 0.0572
Loa Loa (eye worm) 6-phosphofructokinase 0.0105 0.0464 0.0462
Trichomonas vaginalis bmru protein, putative 0.0077 0.0322 0.1842
Echinococcus granulosus JmjC domain containing protein 4 0.0015 0.0008 0.0007
Brugia malayi acetyltransferase, GNAT family protein 0.0145 0.0666 0.408
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0123 0.0554 0.1857
Loa Loa (eye worm) hypothetical protein 0.0334 0.1629 0.1628
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0097 0.0438
Schistosoma mansoni blooms syndrome DNA helicase 0.0052 0.0193 0.0193
Loa Loa (eye worm) hypothetical protein 0.003 0.0082 0.008
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0027 0.0067 0.0414
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0028 0.0074 0.0407
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0035 0.0108 0.034
Loa Loa (eye worm) hypothetical protein 0.0046 0.0165 0.0164
Brugia malayi isocitrate dehydrogenase 0.0015 0.0008 0.004
Loa Loa (eye worm) latrophilin receptor protein 2 0.0062 0.0243 0.0241
Brugia malayi hypothetical protein 0.0035 0.0108 0.0654
Onchocerca volvulus Bile acid receptor homolog 0.003 0.0082 0.0715
Echinococcus multilocularis histone acetyltransferase MYST2 0.0053 0.0202 0.02
Loa Loa (eye worm) hypothetical protein 0.0077 0.0322 0.0321
Brugia malayi mbt repeat family protein 0.0047 0.0169 0.1027
Schistosoma mansoni sphingosine kinase A B 0.198 1 1
Schistosoma mansoni amine oxidase 0.0025 0.0058 0.0058
Echinococcus granulosus histone acetyltransferase KAT2B 0.0136 0.0622 0.0621
Entamoeba histolytica acyl-coA synthetase, putative 0.0046 0.0165 0.0165
Loa Loa (eye worm) bromodomain containing protein 0.0038 0.0124 0.0122
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0027 0.0000000003541
Trichomonas vaginalis penicillin-binding protein, putative 0.0071 0.0289 0.1637
Leishmania major DNA polymerase kappa, putative 0.0117 0.0526 0.1762
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0089 0.0089
Loa Loa (eye worm) hypothetical protein 0.0083 0.0354 0.0353
Trichomonas vaginalis diacylglycerol kinase, zeta, iota, putative 0.0077 0.0322 0.1842
Trypanosoma cruzi hypothetical protein, conserved 0.0071 0.0289 0.0957
Brugia malayi Nuclear hormone receptor family member nhr-25 0.003 0.0082 0.0494
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0046 0.0165 0.0157
Brugia malayi nuclear receptor NHR-88 0.003 0.0082 0.0494
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0056 0.0214 0.0206
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0123 0.0554 0.1857
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0028 0.0074 0.0101
Loa Loa (eye worm) hypothetical protein 0.0085 0.036 0.0358
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0053 0.0202 0.02
Leishmania major DNA damage repair protein, putative 0.0032 0.0094 0.0293
Toxoplasma gondii diacylglycerol kinase, putative 0.0077 0.0322 0.1977
Schistosoma mansoni retinoic acid receptor RXR 0.003 0.0082 0.0082
Trypanosoma brucei Sphingosine kinase 0.0077 0.0322 0.1069
Entamoeba histolytica diacylglycerol kinase, putative 0.0077 0.0322 0.0322
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0015 0.0008 0.0008
Loa Loa (eye worm) transcription factor SMAD2 0.0116 0.0521 0.052
Loa Loa (eye worm) hypothetical protein 0.0015 0.0008 0.0007
Trichomonas vaginalis phosphofructokinase, putative 0.0028 0.0074 0.0294
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.003 0.0082 0.0082
Loa Loa (eye worm) hypothetical protein 0.0035 0.0106 0.0104
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0062 0.0243 0.1483
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0047 0.0167 0.0167
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0032 0.0094 0.0579
Echinococcus granulosus neuropeptide s receptor 0.0447 0.2202 0.2201
Schistosoma mansoni DNA helicase recq5 0.0027 0.0067 0.0067
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0334 0.1629 1
Schistosoma mansoni apoferritin-2 0.0025 0.0056 0.0056
Echinococcus granulosus zinc finger protein 0.0047 0.0167 0.0166
Schistosoma mansoni ferritin 0.0025 0.0056 0.0056
Loa Loa (eye worm) ceramide kinase 0.0077 0.0322 0.0321
Trypanosoma cruzi DNA damage repair protein, putative 0.0032 0.0094 0.0293
Mycobacterium ulcerans hypothetical protein 0.198 1 1
Loa Loa (eye worm) hypothetical protein 0.0071 0.0289 0.0288
Loa Loa (eye worm) CXXC zinc finger family protein 0.0084 0.0359 0.0357
Toxoplasma gondii phosphofructokinase PFKII 0.0028 0.0074 0.0455
Loa Loa (eye worm) hypothetical protein 0.0152 0.0705 0.0704
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0027 0.0067 0.0366
Echinococcus multilocularis GPCR, family 2 0.0062 0.0243 0.0241
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0016 0.001 0.0009
Mycobacterium leprae Probable lipase LipE 0.0071 0.0289 0.1483
Loa Loa (eye worm) beta-lactamase 0.0071 0.0289 0.0288
Toxoplasma gondii diacylglycerol kinase catalytic domain-containing protein 0.0077 0.0322 0.1977
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0047 0.0167 0.0165
Echinococcus granulosus methyl CpG binding domain protein 2 0.0033 0.01 0.0099
Echinococcus granulosus beta LACTamase domain containing family member 0.0071 0.0289 0.0288
Trypanosoma cruzi DNA polymerase eta, putative 0.0082 0.0349 0.1159
Trypanosoma brucei DNA polymerase eta, putative 0.0154 0.0714 0.2404
Onchocerca volvulus 0.0031 0.0089 0.0775
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.003 0.0082 0.008
Brugia malayi Nuclear hormone receptor family member nhr-40 0.003 0.0082 0.0494
Leishmania major phosphoglycerate kinase C, glycosomal 0.0334 0.1629 0.5519
Trichomonas vaginalis phosphofructokinase, putative 0.0105 0.0464 0.2727
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0105 0.0464 0.0456
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0014 0.0002 0.0002
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0027 0.0067 0.0405
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0065 0.0259 0.0257
Trypanosoma brucei DNA polymerase kappa, putative 0.0156 0.0725 0.2442
Loa Loa (eye worm) hypothetical protein 0.003 0.0082 0.008
Schistosoma mansoni ap endonuclease 0.0056 0.0214 0.0214
Schistosoma mansoni cpg binding protein 0.0093 0.0402 0.0402
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0046 0.0163 0.1
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0035 0.0106 0.0302
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.0096 0.0088
Brugia malayi PHD-finger family protein 0.0057 0.0221 0.1345
Brugia malayi F/Y-rich N-terminus family protein 0.0031 0.0085 0.0515
Schistosoma mansoni hypothetical protein 0.0062 0.0243 0.0243
Echinococcus granulosus lysine specific demethylase 5A 0.0066 0.0268 0.0266
Trypanosoma cruzi hypothetical protein, conserved 0.0032 0.0094 0.0293
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.003 0.0082 0.008
Echinococcus multilocularis Diacylglycerol kinase theta 0.0077 0.0322 0.0321
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0027 0.0000000003541
Loa Loa (eye worm) hypothetical protein 0.0065 0.0259 0.0257
Loa Loa (eye worm) hypothetical protein 0.0016 0.001 0.0009
Schistosoma mansoni 6-phosphofructokinase 0.0105 0.0464 0.0464
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0025 0.0058 0.031
Trichomonas vaginalis phosphofructokinase, putative 0.0028 0.0074 0.0294
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0102 0.0447 0.1493
Mycobacterium ulcerans acyl-CoA synthetase 0.0046 0.0165 0.011
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0593 0.2946 1
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0027 0.0068 0.0066
Schistosoma mansoni hypothetical protein 0.0062 0.0243 0.0243
Echinococcus granulosus lysine specific histone demethylase 1A 0.0025 0.0058 0.0057
Trichomonas vaginalis phosphofructokinase, putative 0.0028 0.0074 0.0294
Schistosoma mansoni ferritin light chain 0.0025 0.0056 0.0056
Brugia malayi ImpB/MucB/SamB family protein 0.0154 0.0714 0.4378
Plasmodium falciparum JmjC domain-containing protein, putative 0.0015 0.0008 0.0002
Echinococcus granulosus ceramide kinase 0.0077 0.0322 0.0321
Trypanosoma brucei DNA polymerase IV, putative 0.0156 0.0725 0.2442
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0046 0.0163 0.0955
Schistosoma mansoni retinoid-x-receptor (RXR) 0.003 0.0082 0.0082
Mycobacterium tuberculosis Probable lipase LipD 0.0071 0.0289 0.0281
Schistosoma mansoni terminal deoxycytidyl transferase 0.0104 0.046 0.046
Trypanosoma cruzi hypothetical protein, conserved 0.0032 0.0094 0.0293
Trypanosoma cruzi hypothetical protein, conserved 0.0071 0.0289 0.0957
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.0108 0.0106
Trypanosoma brucei DNA damage repair protein, putative 0.0032 0.0094 0.0293
Leishmania major phosphoglycerate kinase B, cytosolic 0.0334 0.1629 0.5519
Loa Loa (eye worm) jmjC domain-containing protein 0.0015 0.0008 0.0007
Trichomonas vaginalis D-aminoacylase, putative 0.0071 0.0289 0.1637
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.003 0.0082 0.008
Onchocerca volvulus 0.0046 0.0165 0.1456
Giardia lamblia Histone acetyltransferase GCN5 0.0038 0.0122 0.0348
Brugia malayi diacylglycerol kinase 0.0077 0.0322 0.1969
Entamoeba histolytica diacylglycerol kinase, putative 0.0077 0.0322 0.0322
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.003 0.0082 0.008
Trypanosoma brucei unspecified product 0.0072 0.0295 0.0978
Brugia malayi nuclear hormone receptor 0.003 0.0082 0.0494
Trichomonas vaginalis sphingosine kinase, putative 0.0077 0.0322 0.1842
Echinococcus multilocularis JmjC domain containing protein 4 0.0015 0.0008 0.0007
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.003 0.0082 0.008
Schistosoma mansoni apoferritin-2 0.0025 0.0056 0.0056
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0022 0.0042 0.004
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0105 0.0464 0.2594
Onchocerca volvulus Protein ultraspiracle homolog 0.003 0.0082 0.0715
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0015 0.0008 0.0052
Plasmodium falciparum histone acetyltransferase GCN5 0.0038 0.0122 0.0702
Schistosoma mansoni zinc finger protein 0.0014 0.0002 0.0002
Schistosoma mansoni mixed-lineage leukemia protein mll 0.018 0.0845 0.0845
Trypanosoma cruzi ISWI complex protein 0.003 0.0083 0.0254
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0049 0.0179 0.0178
Plasmodium vivax 6-phosphofructokinase, putative 0.0028 0.0074 0.0407
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0062 0.0243 0.0241
Plasmodium vivax diacylglycerol kinase, putative 0.0077 0.0322 0.1937
Brugia malayi Bromodomain containing protein 0.0079 0.033 0.2016
Toxoplasma gondii histone lysine-specific demethylase 0.0025 0.0058 0.0358
Echinococcus granulosus phosphoglycerate kinase 1 0.0334 0.1629 0.1628
Loa Loa (eye worm) hypothetical protein 0.0071 0.0289 0.0288
Mycobacterium tuberculosis Conserved hypothetical protein 0.0104 0.046 0.0452
Chlamydia trachomatis phosphoglycerate kinase 0.0334 0.1629 1
Brugia malayi Isocitrate dehydrogenase 0.0015 0.0008 0.004
Echinococcus multilocularis alkaline phosphatase 0.016 0.0745 0.0743
Brugia malayi glutaminase DH11.1 0.0269 0.1299 0.7973
Brugia malayi Nuclear hormone receptor family member nhr-49 0.003 0.0082 0.0494
Mycobacterium tuberculosis Conserved protein 0.0071 0.0289 0.0281
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.003 0.0082 0.008
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0156 0.0725 0.4358
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0016 0.001 0.001
Schistosoma mansoni bromodomain containing protein 0.0017 0.0014 0.0014
Entamoeba histolytica phosphoglycerate kinase, putative 0.0334 0.1629 0.1629
Brugia malayi AMP-binding enzyme family protein 0.0046 0.0165 0.1005
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0056 0.0214 0.0701
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0047 0.0167 0.0165
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0359 0.1754 0.1708
Trypanosoma brucei phosphoglycerate kinase, putative 0.0123 0.0554 0.1857
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0058 0.0224 0.0223
Onchocerca volvulus 0.0084 0.0359 0.3176
Echinococcus granulosus jumonji domain containing 1A 0.0015 0.0008 0.0007
Mycobacterium ulcerans phosphoglycerate kinase 0.0334 0.1629 0.1582
Trypanosoma cruzi DNA polymerase kappa, putative 0.0156 0.0725 0.2442
Wolbachia endosymbiont of Brugia malayi phosphoglycerate kinase 0.0334 0.1629 1
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0027 0.0067 0.0066
Schistosoma mansoni hypothetical protein 0.0165 0.0769 0.0769
Mycobacterium ulcerans dehydrogenase 0.0025 0.0058 0.0002
Mycobacterium ulcerans monoamine oxidase 0.0025 0.0058 0.0002
Echinococcus granulosus dna polymerase eta 0.0154 0.0714 0.0713
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0027 0.0067 0.0414
Brugia malayi 6-phosphofructokinase 0.0105 0.0464 0.2841
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0071 0.0289 0.0281
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.0096 0.0088
Brugia malayi nuclear receptor RXR 0.0016 0.001 0.0053
Loa Loa (eye worm) MH2 domain-containing protein 0.0116 0.0521 0.052
Loa Loa (eye worm) hypothetical protein 0.0035 0.0106 0.0104
Echinococcus multilocularis neuropeptide s receptor 0.0447 0.2202 0.2201
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0065 0.0259 0.0259
Plasmodium vivax diacylglycerol kinase, putative 0.0077 0.0322 0.1937
Treponema pallidum bacterioferrin (TpF1) 0.0025 0.0056 0.0344
Loa Loa (eye worm) hypothetical protein 0.003 0.0082 0.008
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0123 0.0554 0.1857
Plasmodium vivax acyl-CoA synthetase, putative 0.0035 0.0106 0.0602
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.013 0.0589 0.1978
Loa Loa (eye worm) MBCTL1 0.0053 0.0202 0.02
Trypanosoma cruzi DNA damage repair protein, putative 0.0032 0.0094 0.0293
Loa Loa (eye worm) hypothetical protein 0.0062 0.0243 0.0241
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0071 0.0289 0.0287
Brugia malayi diacylglycerol kinase 0.0077 0.0322 0.1969
Trichomonas vaginalis ferritin, putative 0.0025 0.0056 0.0181
Schistosoma mansoni hypothetical protein 0.0165 0.0769 0.0769
Echinococcus granulosus transcription factor Dp 1 0.0075 0.0311 0.031
Echinococcus multilocularis beta LACTamase domain containing family member 0.0071 0.0289 0.0288
Schistosoma mansoni ferritin 0.0025 0.0056 0.0056
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0056 0.0214 0.1269
Schistosoma mansoni DNA polymerase eta 0.0154 0.0714 0.0714
Entamoeba histolytica hypothetical protein 0.0035 0.0108 0.0108
Entamoeba histolytica diacylglycerol kinase, putative 0.0077 0.0322 0.0322
Trypanosoma cruzi DNA polymerase kappa, putative 0.0156 0.0725 0.2442
Loa Loa (eye worm) hypothetical protein 0.0195 0.092 0.0918
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.003 0.0082 0.008
Trichomonas vaginalis conserved hypothetical protein 0.0077 0.0322 0.1842
Trypanosoma cruzi Diacylglycerol kinase catalytic domain containing protein, putative 0.0077 0.0322 0.1069
Mycobacterium ulcerans acyl-CoA synthetase 0.0046 0.0165 0.011
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0015 0.0008 0.0007
Trichomonas vaginalis ap endonuclease, putative 0.0056 0.0214 0.1166
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0015 0.0008 0.0007
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0071 0.0289 0.0281
Echinococcus multilocularis transcription factor Dp 1 0.0075 0.0311 0.031
Mycobacterium ulcerans 6-phosphofructokinase 0.0105 0.0464 0.041
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0281 0.1357 0.4592
Schistosoma mansoni alkaline phosphatase 0.016 0.0745 0.0745
Loa Loa (eye worm) hypothetical protein 0.003 0.0082 0.008
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0062 0.0243 0.0241
Loa Loa (eye worm) jmjC domain-containing protein 0.0015 0.0008 0.0007
Schistosoma mansoni sphingoid long chain base kinase 0.198 1 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.003 0.0082 0.008
Echinococcus granulosus alkaline phosphatase intestinal gene 2 0.016 0.0745 0.0743
Schistosoma mansoni myelin transcription factor 1 myt1 0.0053 0.0202 0.0202
Schistosoma mansoni diacylglycerol kinase zeta iota 0.0077 0.0322 0.0322
Trypanosoma brucei hypothetical protein, conserved 0.0032 0.0094 0.0293
Onchocerca volvulus 0.0235 0.1126 1
Brugia malayi Nuclear hormone receptor-like 1 0.0016 0.001 0.0053
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0032 0.0093 0.0093
Schistosoma mansoni ap endonuclease 0.0056 0.0214 0.0214
Trypanosoma brucei hypothetical protein, conserved 0.0071 0.0289 0.0957
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0028 0.0074 0.0043
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0195 0.092 0.564
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0035 0.0106 0.0098
Loa Loa (eye worm) hypothetical protein 0.0077 0.0322 0.0321
Trichomonas vaginalis bmru protein, putative 0.0077 0.0322 0.1842
Loa Loa (eye worm) PHD-finger family protein 0.0041 0.0136 0.0134
Mycobacterium tuberculosis Conserved hypothetical protein 0.0025 0.0058 0.005
Trypanosoma cruzi Sphingosine kinase 0.0077 0.0322 0.1069
Trypanosoma brucei DNA polymerase IV, putative 0.0143 0.0659 0.2217
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0083 0.0354 0.1177
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0105 0.0464 0.2848
Plasmodium vivax protoporphyrinogen oxidase, putative 0.0025 0.0058 0.031
Onchocerca volvulus 0.0071 0.0289 0.2559
Schistosoma mansoni jumonji domain containing protein 0.0058 0.0224 0.0224
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0015 0.0008 0.0052
Brugia malayi Phosphoglycerate kinase 0.0334 0.1629 1
Echinococcus multilocularis jumonji domain containing 1A 0.0015 0.0008 0.0007
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0058 0.0223 0.1324
Trypanosoma cruzi DNA polymerase kappa, putative 0.0156 0.0725 0.2442
Leishmania major DNA polymerase eta, putative 0.0154 0.0714 0.2404
Onchocerca volvulus Ceramide kinase 1 homolog 0.0077 0.0322 0.285
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.013 0.0589 0.0587
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0027 0.0000000003541
Schistosoma mansoni methyl-cpg binding protein mbd 0.0033 0.01 0.01
Giardia lamblia DNA damage repair protein 0.0032 0.0094 0.0172
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0031 0.0089 0.0087
Echinococcus granulosus Diacylglycerol kinase zeta 0.0077 0.0322 0.0321
Mycobacterium tuberculosis Probable phosphoglycerate kinase Pgk 0.0334 0.1629 0.1622
Loa Loa (eye worm) phosphofructokinase 0.0105 0.0464 0.0462
Schistosoma mansoni nuclear receptor nhr-48 0.0014 0.0002 0.0002
Mycobacterium tuberculosis Probable hydrolase 0.0071 0.0289 0.0281
Loa Loa (eye worm) hypothetical protein 0.0077 0.0322 0.0321
Schistosoma mansoni cpg binding protein 0.0084 0.0359 0.0359
Mycobacterium ulcerans lipase LipD 0.0071 0.0289 0.0235
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0452 0.2227 0.222
Plasmodium vivax hypothetical protein, conserved 0.0025 0.0058 0.031
Echinococcus multilocularis intestinal type alkaline phosphatase 0.016 0.0745 0.0743
Echinococcus multilocularis dna polymerase kappa 0.0156 0.0725 0.0724
Loa Loa (eye worm) hypothetical protein 0.0047 0.0169 0.0167
Schistosoma mansoni amine oxidase 0.0025 0.0058 0.0058
Schistosoma mansoni diacylglycerol kinase theta 0.0077 0.0322 0.0322
Trichomonas vaginalis phosphofructokinase, putative 0.0105 0.0464 0.2727
Leishmania major 4-coumarate:coa ligase-like protein 0.0046 0.0165 0.0535
Loa Loa (eye worm) hypothetical protein 0.003 0.0082 0.008
Brugia malayi Diacylglycerol kinase protein 2 0.0077 0.0322 0.1969
Leishmania major hypothetical protein, conserved 0.0077 0.0322 0.1069
Entamoeba histolytica deoxycytidyl transferase, putative 0.0104 0.046 0.046
Echinococcus multilocularis lysine specific histone demethylase 1A 0.0025 0.0058 0.0057
Loa Loa (eye worm) hypothetical protein 0.003 0.0082 0.008
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0033 0.0097 0.0096
Echinococcus multilocularis polycomb protein SCMH1 0.0047 0.0169 0.0167
Trypanosoma brucei phosphoglycerate kinase 0.0334 0.1629 0.5519
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0028 0.0074 0.0294
Loa Loa (eye worm) isocitrate dehydrogenase 0.0015 0.0008 0.0007
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0046 0.0165 0.011
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0593 0.2946 1
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0035 0.0108 0.034
Trypanosoma cruzi hypothetical protein, conserved 0.0077 0.0322 0.1069
Entamoeba histolytica acyl-CoA synthetase, putative 0.0046 0.0165 0.0165
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0046 0.0165 0.011
Leishmania major hypothetical protein, conserved 0.0071 0.0289 0.0957
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0033 0.01 0.0099
Trichomonas vaginalis bromodomain-containing protein, putative 0.0046 0.0163 0.0848
Toxoplasma gondii exonuclease III APE 0.0056 0.0214 0.1313
Brugia malayi Latrophilin receptor protein 2 0.0062 0.0243 0.1483
Echinococcus multilocularis bloom syndrome protein 0.0066 0.0263 0.0262
Echinococcus multilocularis ceramide kinase 0.0077 0.0322 0.0321
Echinococcus granulosus ferritin 0.0025 0.0056 0.0054
Loa Loa (eye worm) hypothetical protein 0.0016 0.001 0.0009
Loa Loa (eye worm) hypothetical protein 0.0053 0.0202 0.02
Loa Loa (eye worm) hypothetical protein 0.0035 0.0106 0.0104
Plasmodium vivax hypothetical protein, conserved 0.0071 0.0289 0.1735
Loa Loa (eye worm) eye-specific diacylglycerol kinase 0.0077 0.0322 0.0321
Toxoplasma gondii isocitrate dehydrogenase 0.0015 0.0008 0.005
Schistosoma mansoni phosphatidylserine receptor 0.0015 0.0008 0.0008
Trypanosoma brucei DNA polymerase kappa, putative 0.0156 0.0725 0.2442
Loa Loa (eye worm) jmjC domain-containing protein 0.0066 0.0268 0.0266
Echinococcus multilocularis geminin 0.0165 0.0769 0.0768
Schistosoma mansoni methyl-cpg binding protein mbd 0.0033 0.01 0.01
Brugia malayi Nuclear hormone receptor family member nhr-25 0.003 0.0082 0.0494
Loa Loa (eye worm) hypothetical protein 0.0046 0.0165 0.0164
Schistosoma mansoni phd/f-box containing protein 0.0015 0.0008 0.0008
Brugia malayi AMP-binding enzyme family protein 0.0046 0.0165 0.1005
Mycobacterium tuberculosis Conserved hypothetical protein 0.0312 0.1518 0.1511
Mycobacterium tuberculosis Possible oxidoreductase 0.0025 0.0058 0.005
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.013 0.0589 0.3609
Plasmodium falciparum protoporphyrinogen oxidase 0.0025 0.0058 0.031
Schistosoma mansoni nuclear receptor 0.0014 0.0002 0.0002
Toxoplasma gondii ABC1 family protein 0.0071 0.0289 0.1776
Echinococcus multilocularis FTZ F1 alpha 0.003 0.0082 0.008
Schistosoma mansoni Lysine-specific histone demethylase 1 0.0025 0.0058 0.0058
Treponema pallidum phosphoglycerate kinase 0.0334 0.1629 1
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0032 0.0093 0.029
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0334 0.1629 0.5519
Brugia malayi Nuclear hormone receptor family member nhr-3 0.003 0.0082 0.0494
Entamoeba histolytica hypothetical protein 0.0035 0.0108 0.0108
Echinococcus granulosus SAM and MBT domain containing protein 0.0047 0.0169 0.0167
Plasmodium falciparum lysine-specific histone demethylase 1, putative 0.0025 0.0058 0.031
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0071 0.0289 0.0289
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0058 0.0224 0.0223
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0207 0.0982 0.098
Schistosoma mansoni Tr4/Tr2 (homologue) 0.003 0.0082 0.0082
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0593 0.2946 1
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.013 0.0589 0.1978
Mycobacterium ulcerans DNA polymerase IV 0.0156 0.0725 0.0673
Mycobacterium ulcerans hypothetical protein 0.0046 0.0165 0.011
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0015 0.0008 0.0007
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0027 0.0068 0.0066
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.013 0.0589 0.0587
Loa Loa (eye worm) hypothetical protein 0.0025 0.0058 0.0057
Schistosoma mansoni sex comb on midleg homolog 0.0047 0.0169 0.0169
Echinococcus multilocularis isocitrate dehydrogenase 0.0015 0.0008 0.0007
Trypanosoma brucei hypothetical protein, conserved 0.0077 0.0322 0.1069
Mycobacterium ulcerans hypothetical protein 0.0312 0.1518 0.1471
Echinococcus granulosus histone acetyltransferase MYST2 0.0053 0.0202 0.02
Trypanosoma brucei hypothetical protein, conserved 0.0032 0.0094 0.0293
Mycobacterium tuberculosis Conserved protein 0.0071 0.0289 0.0281
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0062 0.0243 0.0241
Loa Loa (eye worm) hypothetical protein 0.0046 0.0165 0.0164
Schistosoma mansoni hypothetical protein 0.1201 0.6037 0.6037
Echinococcus multilocularis lysine specific demethylase 6a 0.0015 0.0008 0.0007
Toxoplasma gondii diacylglycerol kinase accessory domain (presumed) domain-containing protein 0.0077 0.0322 0.1977
Brugia malayi 6-phosphofructokinase 0.0105 0.0464 0.2841
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0027 0.0067 0.0066
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0022 0.0042 0.004
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0035 0.0108 0.034
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0056 0.0214 0.1269
Mycobacterium ulcerans esterase/lipase LipP 0.0071 0.0289 0.0235
Brugia malayi hypothetical protein 0.0016 0.001 0.0053
Loa Loa (eye worm) hypothetical protein 0.0015 0.0008 0.0007
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0022 0.0042 0.0042
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0046 0.0165 0.011
Echinococcus granulosus retinoic acid receptor rxr beta a 0.003 0.0082 0.008
Mycobacterium tuberculosis Probable lipase LipE 0.0071 0.0289 0.0281
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0082 0.0349 0.214
Schistosoma mansoni RAR-like nuclear receptor 0.003 0.0082 0.0082
Entamoeba histolytica hypothetical protein 0.0035 0.0108 0.0108
Schistosoma mansoni jumonji domain containing protein 0.0015 0.0008 0.0008
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.003 0.0082 0.0494
Echinococcus multilocularis acylglycerol kinase, mitochondrial 0.0077 0.0322 0.0321
Loa Loa (eye worm) hypothetical protein 0.0092 0.0398 0.0396
Echinococcus granulosus histone lysine methyltransferase setb 0.0065 0.0259 0.0257
Schistosoma mansoni thyroid hormone receptor 0.003 0.0082 0.0082
Trichomonas vaginalis ap endonuclease, putative 0.0056 0.0214 0.1166
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0071 0.0289 0.0281
Echinococcus multilocularis phosphoglycerate kinase 1 0.0334 0.1629 0.1628
Trypanosoma brucei diacylglycerol kinase, putative 0.0077 0.0322 0.1069
Echinococcus granulosus intestinal type alkaline phosphatase 1 0.016 0.0745 0.0743
Brugia malayi jmjC domain containing protein 0.0015 0.0008 0.0042
Echinococcus granulosus cpg binding protein 0.0093 0.0402 0.0401
Echinococcus granulosus bloom syndrome protein 0.0066 0.0263 0.0262
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0125 0.0568 0.0566
Entamoeba histolytica phosphofructokinase, putative 0.0105 0.0464 0.0464
Loa Loa (eye worm) hypothetical protein 0.0133 0.0606 0.0605
Plasmodium vivax JmjC domain containing protein 0.0015 0.0008 0.0002
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.003 0.0082 0.008
Entamoeba histolytica phosphofructokinase, putative 0.0105 0.0464 0.0464
Echinococcus granulosus geminin 0.0165 0.0769 0.0768
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0027 0.0067 0.0066
Schistosoma mansoni hypothetical protein 0.0077 0.0322 0.0322
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0015 0.0008 0.0007
Mycobacterium tuberculosis Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) 0.0333 0.1625 0.1619
Trypanosoma cruzi diacylglycerol kinase-like protein, putative 0.0077 0.0322 0.1069
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.003 0.0082 0.0494
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0047 0.0167 0.0165
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0047 0.0167 0.0165
Echinococcus multilocularis phd:f box containing protein 0.0015 0.0008 0.0007
Brugia malayi jmjC domain containing protein 0.0058 0.0224 0.1369
Entamoeba histolytica hypothetical protein, conserved 0.198 1 1
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0019 0.0027 0.0000000003541
Schistosoma mansoni jumonji/arid domain-containing protein 0.0066 0.0268 0.0268
Onchocerca volvulus 0.003 0.0082 0.0715
Loa Loa (eye worm) hypothetical protein 0.0017 0.0014 0.0013
Trypanosoma brucei Diacylglycerol kinase catalytic domain containing protein, putative 0.0077 0.0322 0.1069
Brugia malayi Nuclear hormone receptor family member nhr-1 0.003 0.0082 0.0494
Loa Loa (eye worm) hypothetical protein 0.0016 0.001 0.0009
Schistosoma mansoni glutaminase 0.0269 0.1299 0.1299
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0045 0.016 0.0983
Schistosoma mansoni DNA helicase recq1 0.0027 0.0067 0.0067
Entamoeba histolytica diacylglycerol kinase, putative 0.0077 0.0322 0.0322
Trichomonas vaginalis glutaminase, putative 0.0269 0.1299 0.7941
Echinococcus multilocularis expressed protein 0.0033 0.0097 0.0096
Trypanosoma cruzi diacylglycerol kinase, putative 0.0077 0.0322 0.1069
Entamoeba histolytica phosphofructokinase, putative 0.0105 0.0464 0.0464
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0334 0.1629 1
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.0096 0.0088
Schistosoma mansoni protein phosphatase 2C 0.0015 0.0008 0.0008
Mycobacterium ulcerans acyl-CoA synthetase 0.0046 0.0165 0.011
Toxoplasma gondii histone lysine-specific demethylase LSD1/BHC110/KDMA1A 0.003 0.0084 0.0518
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0281 0.1357 0.4592
Schistosoma mansoni DNA polymerase IV / kappa 0.0032 0.0094 0.0094
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0123 0.0554 0.1857
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0281 0.1357 0.4592
Loa Loa (eye worm) acetyltransferase 0.0145 0.0666 0.0664
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0022 0.0042 0.004
Brugia malayi Pre-SET motif family protein 0.0207 0.0982 0.6022
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0035 0.0106 0.005
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.003 0.0082 0.008
Trichomonas vaginalis DNA helicase recq, putative 0.0035 0.0108 0.0505
Trypanosoma brucei phosphoglycerate kinase 0.0334 0.1629 0.5519
Trichomonas vaginalis phosphofructokinase, putative 0.0028 0.0074 0.0294
Leishmania major hypothetical protein, conserved 0.003 0.0083 0.0254
Schistosoma mansoni hypothetical protein 0.0133 0.0606 0.0606
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0056 0.0214 0.0701
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0046 0.0163 0.1
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.003 0.0082 0.008
Mycobacterium ulcerans protoporphyrinogen oxidase 0.0025 0.0058 0.0002
Schistosoma mansoni bromodomain containing protein 0.0132 0.0604 0.0604
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0083 0.0354 0.1177
Leishmania major DNA polymerase kappa, putative 0.0032 0.0094 0.0293
Mycobacterium ulcerans glutaminase 0.0269 0.1299 0.125
Trichomonas vaginalis DNA helicase recq1, putative 0.0066 0.0263 0.1474
Trypanosoma brucei ISWI complex protein 0.003 0.0083 0.0254
Plasmodium falciparum diacylglycerol kinase, putative 0.0077 0.0322 0.1937
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0047 0.0167 0.0167
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0024 0.0052 0.005
Schistosoma mansoni ferritin light chain 0.0025 0.0056 0.0056
Trichomonas vaginalis DNA helicase recq, putative 0.0066 0.0263 0.1474
Toxoplasma gondii 6-phosphofructokinase 0.0028 0.0074 0.0455
Schistosoma mansoni rotamase 0.0033 0.0097 0.0097
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0359 0.1754 0.1708
Trypanosoma brucei phosphoglycerate kinase 0.0123 0.0554 0.1857
Leishmania major diacylglycerol kinase-like protein 0.0077 0.0322 0.1069
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.003 0.0082 0.0082
Schistosoma mansoni cpg binding protein 0.0093 0.0402 0.0402
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0125 0.0568 0.0566
Trichomonas vaginalis diacylglycerol kinase, zeta, iota, putative 0.0077 0.0322 0.1842
Schistosoma mansoni Protoporphyrinogen oxidase chloroplast/mitochondrial precursor 0.0025 0.0058 0.0058
Brugia malayi Eye-specific diacylglycerol kinase 0.0077 0.0322 0.1969
Trypanosoma brucei DNA polymerase kappa, putative 0.0085 0.036 0.1197
Brugia malayi Pre-SET motif family protein 0.0031 0.0089 0.0535
Echinococcus granulosus expressed protein 0.0025 0.0056 0.0054
Trypanosoma cruzi DNA polymerase kappa, putative 0.0156 0.0725 0.2442
Schistosoma mansoni alkaline phosphatase 0.016 0.0745 0.0745
Trypanosoma brucei DNA polymerase kappa, putative 0.0085 0.0361 0.1202
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0334 0.1629 0.5519
Toxoplasma gondii phosphoglycerate kinase PGKII 0.0334 0.1629 1
Leishmania major DNA polymerase eta, putative 0.0082 0.0349 0.1159
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0046 0.0165 0.0695
Echinococcus granulosus dnaJ subfamily B 0.1201 0.6037 0.6037
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0024 0.0052 0.005
Entamoeba histolytica acyl-CoA synthetase, putative 0.0046 0.0165 0.0165
Echinococcus multilocularis ecdysone induced protein 78C 0.003 0.0082 0.008
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0028 0.0074 0.0407
Echinococcus multilocularis dna polymerase eta 0.0154 0.0714 0.0713
Trichomonas vaginalis rotamase, putative 0.0033 0.0097 0.0438
Mycobacterium tuberculosis Bacterioferritin BfrB 0.0025 0.0056 0.0048
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0104 0.046 0.0458
Toxoplasma gondii histone lysine methyltransferase SET1 0.0169 0.0789 0.4842
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0071 0.0289 0.1768
Trypanosoma cruzi diacylglycerol kinase-like protein, putative 0.0077 0.0322 0.1069
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0195 0.092 0.0918
Toxoplasma gondii isocitrate dehydrogenase 0.0015 0.0008 0.005
Leishmania major hypothetical protein, conserved 0.0015 0.0008 0.0001
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0031 0.0089 0.0545
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0032 0.0093 0.029
Trichomonas vaginalis DNA polymerase eta, putative 0.0156 0.0725 0.4358
Trypanosoma cruzi ISWI complex protein 0.003 0.0083 0.0254
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.0096 0.0088
Brugia malayi jmjC domain containing protein 0.0015 0.0008 0.0042
Brugia malayi Calcitonin receptor-like protein seb-1 0.0195 0.092 0.564
Echinococcus multilocularis 0.0025 0.0058 0.0057
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0016 0.001 0.0009
Trypanosoma cruzi UDP-galactopyranose mutase 0.0025 0.0058 0.0171
Treponema pallidum exodeoxyribonuclease (exoA) 0.0056 0.0214 0.1313
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0056 0.0214 0.1004
Schistosoma mansoni ferritin 0.0025 0.0056 0.0056
Trichomonas vaginalis diacylglycerol kinase, epsilon, putative 0.0077 0.0322 0.1842
Brugia malayi CXXC zinc finger family protein 0.0084 0.0359 0.2194
Loa Loa (eye worm) hypothetical protein 0.0071 0.0289 0.0288
Entamoeba histolytica acetyltransferase, GNAT family 0.0038 0.0122 0.0122
Brugia malayi Ceramide kinase 0.0077 0.0322 0.1969
Trypanosoma brucei DNA polymerase kappa, putative 0.0085 0.0361 0.1202
Echinococcus granulosus acylglycerol kinase mitochondrial 0.0077 0.0322 0.0321
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.003 0.0082 0.0715
Echinococcus granulosus histone acetyltransferase KAT2B 0.0046 0.0163 0.0161
Plasmodium falciparum phosphoglycerate kinase 0.0334 0.1629 1
Schistosoma mansoni 6-phosphofructokinase 0.0105 0.0464 0.0464
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.0108 0.0108
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0117 0.0526 0.1762
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0123 0.0554 0.1857
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0044 0.0153 0.0936
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0056 0.0214 0.0212
Trichomonas vaginalis phosphofructokinase, putative 0.0105 0.0464 0.2727
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0032 0.0093 0.029
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0027 0.0000000003541
Schistosoma mansoni phosphoglycerate kinase 0.0334 0.1629 0.1629
Trypanosoma cruzi Sphingosine kinase 0.0077 0.0322 0.1069
Trypanosoma brucei DNA polymerase kappa, putative 0.0085 0.036 0.1197
Trypanosoma cruzi UDP-galactopyranose mutase 0.0025 0.0058 0.0171
Trypanosoma brucei chrX additional, unordered contigs 0.0032 0.0094 0.0293
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.003 0.0082 0.008
Schistosoma mansoni zinc finger protein 0.0047 0.0167 0.0167
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0044 0.0155 0.0907
Loa Loa (eye worm) histone methyltransferase 0.0027 0.0068 0.0066
Brugia malayi phosphofructokinase 0.0105 0.0464 0.2841
Plasmodium vivax hypothetical protein, conserved 0.0025 0.0058 0.031
Schistosoma mansoni ferritin 0.0025 0.0056 0.0056
Plasmodium falciparum DNA repair protein REV1, putative 0.0032 0.0094 0.0532
Echinococcus granulosus Diacylglycerol kinase theta 0.0077 0.0322 0.0321
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.003 0.0082 0.0082
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.003 0.0082 0.008
Schistosoma mansoni thyroid hormone receptor 0.003 0.0082 0.0082
Brugia malayi beta-lactamase family protein 0.0071 0.0289 0.1768
Trichomonas vaginalis rotamase, putative 0.0032 0.0093 0.0413
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0056 0.0214 0.0938
Schistosoma mansoni hypothetical protein 0.0062 0.0243 0.0243
Trypanosoma brucei DNA polymerase kappa, putative 0.0156 0.0725 0.2442
Brugia malayi beta-lactamase family protein 0.0071 0.0289 0.1768
Brugia malayi photoreceptor-specific nuclear receptor 0.003 0.0082 0.0494
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.003 0.0082 0.008
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0056 0.0214 0.0159
Echinococcus granulosus lysine specific histone demethylase 1A 0.0025 0.0058 0.0057
Trypanosoma cruzi DNA polymerase eta, putative 0.0154 0.0714 0.2404
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0046 0.0165 0.0695
Brugia malayi amine oxidase, flavin-containing family protein 0.0025 0.0058 0.0348
Loa Loa (eye worm) steroid hormone receptor 0.003 0.0082 0.008
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0104 0.046 0.0458
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0015 0.0008 0.0001
Plasmodium vivax phosphoglycerate kinase, putative 0.0334 0.1629 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0027 0.0000000003541
Mycobacterium ulcerans beta-lactamase 0.0071 0.0289 0.0235
Onchocerca volvulus 0.0047 0.0169 0.1486
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0105 0.0464 0.1552
Plasmodium falciparum acyl-CoA synthetase 0.0035 0.0106 0.0602
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0071 0.0289 0.0288
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0015 0.0008 0.0008
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.003 0.0082 0.0082
Trichomonas vaginalis D-aminoacylase, putative 0.0071 0.0289 0.1637
Trichomonas vaginalis penicillin-binding protein, putative 0.0071 0.0289 0.1637
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.013 0.0589 0.0587
Loa Loa (eye worm) hypothetical protein 0.0025 0.0058 0.0057
Trypanosoma brucei DNA polymerase kappa, putative 0.0156 0.0725 0.2442
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0145 0.0666 0.0666
Schistosoma mansoni proteasome subunit alpha 6 (T01 family) 0.0077 0.0322 0.0322
Trypanosoma brucei unspecified product 0.0143 0.0659 0.2217
Onchocerca volvulus 0.0077 0.0322 0.285
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.003 0.0082 0.008
Echinococcus granulosus intestinal type alkaline phosphatase 0.016 0.0745 0.0743
Loa Loa (eye worm) RecQ helicase 0.0066 0.0263 0.0262
Trypanosoma brucei DNA polymerase IV, putative 0.0156 0.0725 0.2442
Trichomonas vaginalis phosphofructokinase, putative 0.0028 0.0074 0.0294
Plasmodium vivax DNA repair protein REV1, putative 0.0032 0.0094 0.0532
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.0025 0.0056 0.0048
Brugia malayi jmjC domain containing protein 0.0066 0.0268 0.1636
Brugia malayi Nuclear hormone receptor family member nhr-41 0.003 0.0082 0.0494
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0047 0.0169 0.1486
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0027 0.0067 0.0405
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0027 0.0000000003541
Brugia malayi Nuclear hormone receptor family member nhr-31 0.003 0.0082 0.0494
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0053 0.0202 0.02
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0071 0.0289 0.0235
Brugia malayi Nuclear hormone receptor-like 1 0.0016 0.001 0.0053
Brugia malayi mbt repeat family protein 0.0047 0.0169 0.1027
Brugia malayi hypothetical protein 0.0025 0.0058 0.0348
Plasmodium vivax SET domain protein, putative 0.0031 0.0089 0.0497
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0053 0.0202 0.123
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0074 0.0072
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0028 0.0074 0.0455
Echinococcus granulosus mixed lineage leukemia protein mll 0.0022 0.0042 0.004
Brugia malayi ImpB/MucB/SamB family protein 0.0104 0.046 0.2815
Trypanosoma brucei DNA polymerase kappa, putative 0.0117 0.0526 0.1762
Plasmodium vivax 6-phosphofructokinase, putative 0.0028 0.0074 0.0407
Mycobacterium tuberculosis Conserved protein 0.198 1 1
Loa Loa (eye worm) glutaminase 0.0269 0.1299 0.1298
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.013 0.0589 0.1978
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0056 0.0214 0.0701
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0019 0.0027 0.0000000003541
Schistosoma mansoni hypothetical protein 0.0062 0.0243 0.0243
Echinococcus granulosus lysine specific demethylase 6a 0.0015 0.0008 0.0007
Echinococcus multilocularis SAM and MBT domain containing protein 0.0047 0.0169 0.0167
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.013 0.0589 0.0589
Loa Loa (eye worm) hypothetical protein 0.003 0.0082 0.008
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0046 0.0165 0.0157
Entamoeba histolytica recQ family helicase, putative 0.0035 0.0108 0.0108
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0047 0.0167 0.0165
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0028 0.0074 0.0074
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0083 0.0354 0.1177
Trypanosoma brucei unspecified product 0.0072 0.0295 0.0978
Loa Loa (eye worm) hypothetical protein 0.003 0.0082 0.008
Trypanosoma brucei DNA polymerase kappa, putative 0.0156 0.0725 0.2442
Loa Loa (eye worm) hypothetical protein 0.0015 0.0008 0.0007
Trichomonas vaginalis esterase, putative 0.0071 0.0289 0.1637
Loa Loa (eye worm) hypothetical protein 0.0071 0.0289 0.0288
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0196 0.0929 0.0927
Echinococcus multilocularis lysine specific demethylase 5A 0.0058 0.0224 0.0223
Mycobacterium ulcerans hypothetical protein 0.0032 0.0094 0.0039
Echinococcus granulosus nuclear receptor 2DBD gamma 0.003 0.0082 0.008
Mycobacterium leprae Probable phosphoglycerate kinase Pgk 0.0334 0.1629 1
Echinococcus multilocularis ferritin 0.0025 0.0056 0.0054
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0049 0.0179 0.0179
Brugia malayi Nuclear hormone receptor family member nhr-14 0.003 0.0082 0.0494
Trypanosoma brucei DNA polymerase kappa, putative 0.0156 0.0725 0.2442
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0014 0.0002 0.0002
Echinococcus granulosus nuclear receptor 2DBD gamma 0.003 0.0082 0.008
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0056 0.0214 0.0701
Trypanosoma brucei DNA damage repair protein, putative 0.0032 0.0094 0.0293
Onchocerca volvulus 0.0025 0.0058 0.0504
Entamoeba histolytica hypothetical protein 0.0035 0.0108 0.0108
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0027 0.0067 0.0066
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0104 0.046 0.046
Brugia malayi beta-lactamase 0.0071 0.0289 0.1768
Loa Loa (eye worm) hypothetical protein 0.0025 0.0058 0.0057
Schistosoma mansoni nuclear hormone receptor 0.003 0.0082 0.0082
Schistosoma mansoni hypothetical protein 0.0041 0.0136 0.0136
Trichomonas vaginalis sphingosine kinase, putative 0.0077 0.0322 0.1842
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0015 0.0008 0.0001
Trichomonas vaginalis phosphofructokinase, putative 0.0028 0.0074 0.0294
Schistosoma mansoni diacylglycerol kinase theta 0.0077 0.0322 0.0322
Echinococcus granulosus alkaline phosphatase 0.016 0.0745 0.0743
Mycobacterium ulcerans oxidoreductase 0.0025 0.0058 0.0002
Schistosoma mansoni hypothetical protein 0.0297 0.1439 0.1439
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.003 0.0082 0.008
Loa Loa (eye worm) hypothetical protein 0.0016 0.001 0.0009
Schistosoma mansoni zinc finger protein 0.003 0.0083 0.0083
Echinococcus granulosus GPCR family 2 0.0062 0.0243 0.0241
Leishmania major hypothetical protein, conserved 0.0077 0.0322 0.1069
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0015 0.0008 0.0007
Brugia malayi jmjC domain containing protein 0.0015 0.0008 0.0042
Echinococcus multilocularis thyroid hormone receptor alpha 0.003 0.0082 0.008
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0071 0.0289 0.0287
Loa Loa (eye worm) hypothetical protein 0.0027 0.0067 0.0066
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0016 0.001 0.0009
Loa Loa (eye worm) hypothetical protein 0.0154 0.0714 0.0713
Mycobacterium ulcerans DNA polymerase IV 0.0156 0.0725 0.0673
Giardia lamblia DINP protein human, muc B family 0.0117 0.0526 0.2934
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0056 0.0214 0.0212
Loa Loa (eye worm) hypothetical protein 0.0025 0.0058 0.0057
Schistosoma mansoni phosphoglycerate kinase 0.0334 0.1629 0.1629
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0083 0.0354 0.1177
Echinococcus granulosus dna polymerase kappa 0.0156 0.0725 0.0724
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0033 0.0097 0.0587
Toxoplasma gondii phosphoglycerate kinase PGKI 0.0334 0.1629 1
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0015 0.0008 0.0001
Giardia lamblia Phosphoglycerate kinase 0.0334 0.1629 1
Loa Loa (eye worm) hypothetical protein 0.0025 0.0058 0.0057
Brugia malayi latrophilin 2 splice variant baaae 0.0133 0.0606 0.3716
Brugia malayi Bromodomain containing protein 0.0155 0.0721 0.4418
Trypanosoma cruzi diacylglycerol kinase, putative 0.0077 0.0322 0.1069
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0047 0.0167 0.1016
Mycobacterium ulcerans diacylglycerol kinase 0.0077 0.0322 0.0268
Trypanosoma brucei DNA polymerase kappa, putative 0.0085 0.0361 0.1202
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.0108 0.0106
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0027 0.0067 0.0066
Schistosoma mansoni coup transcription factor 0.003 0.0082 0.0082
Mycobacterium tuberculosis Probable esterase LipL 0.0071 0.0289 0.0281
Echinococcus granulosus polycomb protein SCMH1 0.0047 0.0169 0.0167
Loa Loa (eye worm) mbt repeat family protein 0.0047 0.0169 0.0167
Echinococcus multilocularis intestinal type alkaline phosphatase 1 0.016 0.0745 0.0743
Trichomonas vaginalis diacylglycerol kinase, putative 0.0077 0.0322 0.1842
Echinococcus granulosus neuropeptide receptor A26 0.0447 0.2202 0.2201
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0028 0.0074 0.0455
Brugia malayi polk-prov protein 0.0085 0.036 0.2201
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0065 0.0259 0.0259
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0016 0.001 0.001
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0056 0.0214 0.0212
Loa Loa (eye worm) hypothetical protein 0.0075 0.0313 0.0311
Leishmania major ATP-dependent phosphofructokinase 0.0105 0.0464 0.1552
Brugia malayi MH2 domain containing protein 0.0116 0.0521 0.3193
Mycobacterium leprae PROBABLE PROTOPORPHYRINOGEN OXIDASE HEMY (PROTOPORPHYRINOGEN-IX OXIDASE) (PROTOPORPHYRINOGENASE) (PPO) 0.0025 0.0058 0.0015
Loa Loa (eye worm) hypothetical protein 0.0139 0.0636 0.0635
Brugia malayi Bloom's syndrome protein homolog 0.0066 0.0263 0.1607
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0145 0.0666 0.0664
Schistosoma mansoni hypothetical protein 0.0035 0.0108 0.0108
Loa Loa (eye worm) jmjC domain-containing protein 0.0015 0.0008 0.0007
Loa Loa (eye worm) hypothetical protein 0.0025 0.0058 0.0057
Brugia malayi Nuclear hormone receptor family member nhr-19 0.003 0.0082 0.0494
Echinococcus multilocularis dnaJ subfamily B 0.1201 0.6037 0.6037
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0071 0.0289 0.0289
Echinococcus granulosus ecdysone induced protein 78C 0.003 0.0082 0.008
Echinococcus multilocularis neuropeptide receptor A26 0.0447 0.2202 0.2201
Brugia malayi steroid hormone receptor 0.003 0.0082 0.0494
Brugia malayi Steroid receptor seven-up type 2 0.003 0.0082 0.0494
Echinococcus multilocularis Diacylglycerol kinase zeta 0.0077 0.0322 0.0321
Schistosoma mansoni sex comb on midleg homolog 0.0047 0.0169 0.0169
Plasmodium vivax lysine-specific histone demethylase 1, putative 0.0025 0.0058 0.031
Loa Loa (eye worm) 6-phosphofructokinase 0.0105 0.0464 0.0462
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0046 0.0165 0.011
Schistosoma mansoni jumonji/arid domain-containing protein 0.0066 0.0268 0.0268
Trichomonas vaginalis phosphofructokinase, putative 0.0105 0.0464 0.2727
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.013 0.0589 0.0589
Leishmania major mitochondrial DNA polymerase beta 0.0593 0.2946 1
Echinococcus granulosus expressed protein 0.0033 0.0097 0.0096
Mycobacterium ulcerans hypothetical protein 0.0071 0.0289 0.0235
Trypanosoma brucei DNA polymerase kappa, putative 0.0156 0.0725 0.2442
Echinococcus granulosus FTZ F1 alpha 0.003 0.0082 0.008
Leishmania major UDP-galactopyranose mutase 0.0025 0.0058 0.0171
Loa Loa (eye worm) hypothetical protein 0.0071 0.0289 0.0288
Echinococcus granulosus 6 phosphofructokinase 0.0105 0.0464 0.0462
Brugia malayi hypothetical protein 0.0016 0.001 0.0053
Loa Loa (eye worm) hypothetical protein 0.0035 0.0106 0.0104
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0062 0.0243 0.0241
Trichomonas vaginalis diacylglycerol kinase, putative 0.0077 0.0322 0.1842
Onchocerca volvulus 0.0071 0.0289 0.2559
Echinococcus multilocularis 6 phosphofructokinase 0.0105 0.0464 0.0462
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0047 0.0169 0.0169
Loa Loa (eye worm) hypothetical protein 0.0071 0.0289 0.0288
Brugia malayi jmjC domain containing protein 0.0015 0.0008 0.0042
Mycobacterium leprae conserved hypothetical protein 0.0071 0.0289 0.1483
Leishmania major 4-coumarate:coa ligase-like protein 0.0046 0.0165 0.0535
Mycobacterium tuberculosis Conserved protein 0.0071 0.0289 0.0281
Loa Loa (eye worm) diacylglycerol kinase 2 0.0077 0.0322 0.0321
Trichomonas vaginalis D-aminoacylase, putative 0.0071 0.0289 0.1637
Echinococcus multilocularis protoporphyrinogen oxidase 0.0025 0.0058 0.0057
Echinococcus granulosus fetal alzheimer antigen falz 0.0049 0.0179 0.0178
Echinococcus multilocularis sphingosine kinase 1 0.198 1 1
Leishmania major sphingosine kinase A, B, putative 0.0077 0.0322 0.1069
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0117 0.0526 0.0518
Plasmodium falciparum diacylglycerol kinase, putative 0.0077 0.0322 0.1937
Schistosoma mansoni hypothetical protein 0.003 0.0083 0.0083
Schistosoma mansoni steroid hormone receptor ad4bp 0.003 0.0082 0.0082
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0056 0.0214 0.0214
Trichomonas vaginalis set domain proteins, putative 0.0235 0.1126 0.6858
Schistosoma mansoni nuclear hormone receptor 0.0014 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0035 0.0106 0.0104
Trypanosoma cruzi 3-phosphoglycerate kinase, glycosomal 0.0123 0.0554 0.1857
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.003 0.0082 0.008
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0105 0.0464 0.1552
Trypanosoma brucei DNA polymerase kappa, putative 0.0156 0.0725 0.2442
Brugia malayi hypothetical protein 0.0077 0.0322 0.1969
Onchocerca volvulus 0.0017 0.0018 0.0145
Brugia malayi Nuclear hormone receptor-like 1 0.003 0.0082 0.0494
Echinococcus multilocularis alkaline phosphatase, intestinal, gene 2 0.016 0.0745 0.0743
Brugia malayi SWIRM domain containing protein 0.0025 0.0058 0.0348
Echinococcus multilocularis cpg binding protein 0.0093 0.0402 0.0401
Toxoplasma gondii hypothetical protein 0.0096 0.0416 0.2555
Brugia malayi Nuclear hormone receptor family member nhr-19 0.003 0.0082 0.0494
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0104 0.046 0.0458
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0196 0.0929 0.0927
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0046 0.0163 0.0848
Onchocerca volvulus 0.0071 0.0289 0.2559
Brugia malayi ecdysteroid receptor 0.003 0.0082 0.0494
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0031 0.0089 0.0089
Brugia malayi Phosphoglycerate kinase 0.0123 0.0554 0.3392
Mycobacterium tuberculosis Diacylglycerol kinase 0.0077 0.0322 0.0314
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0028 0.0074 0.0101
Brugia malayi AMP-binding enzyme family protein 0.0046 0.0165 0.1005
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0047 0.0167 0.0167
Echinococcus multilocularis expressed protein 0.0025 0.0056 0.0054
Schistosoma mansoni hypothetical protein 0.0083 0.0353 0.0353
Leishmania major 4-coumarate:coa ligase-like protein 0.0046 0.0165 0.0535
Trypanosoma brucei DNA polymerase kappa, putative 0.0156 0.0725 0.2442
Loa Loa (eye worm) hypothetical protein 0.0016 0.001 0.0009
Brugia malayi exodeoxyribonuclease III family protein 0.0056 0.0214 0.1304
Schistosoma mansoni nuclear receptor 0.0014 0.0002 0.0002
Echinococcus granulosus phd:f box containing protein 0.0015 0.0008 0.0007

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 2.33 uM Inhibition of recombinant human MAO-B assessed as inhibition of kynuramine conversion to fluorescent metabolite 4-hydroxyquinoline after 20 mins by fluorescence spectrophotometry ChEMBL. 24012182
IC50 (binding) = 22.5 uM Inhibition of recombinant human MAO-A assessed as inhibition of kynuramine conversion to fluorescent metabolite 4-hydroxyquinoline after 20 mins by fluorescence spectrophotometry ChEMBL. 24012182

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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