Detailed information for compound 1917278

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 1209.61 | Formula: C64H104N16O7
  • H donors: 14 H acceptors: 7 LogP: 8.9 Rotable bonds: 54
    Rule of 5 violations (Lipinski): 3
  • SMILES: NCCCC[C@@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N)CCCNC(=N)N)Cc1c[nH]c2c1cccc2)Cc1c[nH]c2c1cccc2)CCCNC(=N)N)[C@H](CC)C)NC(=O)CCCCCCCCCCCCCCCCC
  • InChi: 1S/C64H104N16O7/c1-4-6-7-8-9-10-11-12-13-14-15-16-17-18-19-35-55(81)75-51(32-24-25-36-65)59(84)80-56(43(3)5-2)62(87)77-52(34-27-38-72-64(69)70)58(83)78-54(40-45-42-74-49-31-23-21-29-47(45)49)61(86)79-53(39-44-41-73-48-30-22-20-28-46(44)48)60(85)76-50(57(66)82)33-26-37-71-63(67)68/h20-23,28-31,41-43,50-54,56,73-74H,4-19,24-27,32-40,65H2,1-3H3,(H2,66,82)(H,75,81)(H,76,85)(H,77,87)(H,78,83)(H,79,86)(H,80,84)(H4,67,68,71)(H4,69,70,72)/t43-,50-,51-,52-,53-,54-,56-/m0/s1
  • InChiKey: AWLXLOLEURZQRJ-IBUUYIBASA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma brucei unspecified product 0.002 0.0021 0.0105
Loa Loa (eye worm) hypothetical protein 0.0021 0.003 0.005
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.0037 0.0163 0.0814
Plasmodium falciparum plasmepsin IV 0.0041 0.0201 0.0707
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0148 0.1118 0.1118
Loa Loa (eye worm) hypothetical protein 0.0169 0.1305 0.2195
Echinococcus granulosus Tubulin beta 2C chain 0.0049 0.0272 0.0272
Entamoeba histolytica tubulin family protein 0.0049 0.0272 0.1356
Echinococcus granulosus G protein coupled receptor 139 0.0148 0.1118 0.1118
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.0037 0.0163 0.0814
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0091 0.0635 0.0635
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0091 0.0635 0.0738
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0027 0.0079 0.0092
Leishmania major lanosterol synthase, putative 0.003 0.0109 0.0541
Echinococcus multilocularis g-protein coupled receptor 0.0148 0.1118 0.1118
Schistosoma mansoni thyroid hormone receptor 0.002 0.0019 0.0022
Brugia malayi PAN domain containing protein 0.0039 0.0189 0.0317
Loa Loa (eye worm) hypothetical protein 0.0148 0.1118 0.188
Loa Loa (eye worm) hypothetical protein 0.0148 0.1118 0.188
Echinococcus granulosus GPCR family 2 0.0064 0.0398 0.0398
Schistosoma mansoni hypothetical protein 0.0138 0.1035 0.1203
Brugia malayi Ets-domain containing protein 0.0145 0.1094 0.1841
Leishmania major beta tubulin 0.0049 0.0272 0.1356
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0021 0.0105
Loa Loa (eye worm) transcription factor SMAD2 0.0265 0.2124 0.3572
Echinococcus granulosus tubulin subunit beta 0.0049 0.0272 0.0272
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0148 0.1118 0.1299
Brugia malayi Nuclear hormone receptor-like 1 0.002 0.0019 0.0032
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0021 0.0105
Plasmodium falciparum plasmepsin VII 0.0041 0.0201 0.0707
Echinococcus multilocularis SAM and MBT domain containing protein 0.0046 0.0248 0.0248
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.002 0.0019 0.0019
Plasmodium vivax tubulin beta chain, putative 0.0049 0.0272 0.0924
Loa Loa (eye worm) MH2 domain-containing protein 0.0018 0.0004 0.0007
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.002 0.0019 0.0019
Echinococcus granulosus g protein coupled receptor 0.0148 0.1118 0.1118
Leishmania major beta tubulin 0.0049 0.0272 0.1356
Loa Loa (eye worm) BEN-1 protein 0.0049 0.0272 0.0457
Loa Loa (eye worm) PAN domain-containing protein 0.0039 0.0189 0.0317
Loa Loa (eye worm) hypothetical protein 0.0069 0.044 0.074
Echinococcus multilocularis ets variant gene 4 0.0021 0.003 0.003
Loa Loa (eye worm) hypothetical protein 0.0021 0.0027 0.0046
Loa Loa (eye worm) hypothetical protein 0.0025 0.0064 0.0107
Loa Loa (eye worm) hypothetical protein 0.0148 0.1118 0.188
Echinococcus multilocularis somatostatin receptor 0.0148 0.1118 0.1118
Loa Loa (eye worm) tubulin beta-2A chain 0.0049 0.0272 0.0457
Loa Loa (eye worm) histone deacetylase 7A 0.0186 0.1452 0.2443
Giardia lamblia Beta tubulin 0.0049 0.0272 0.1356
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0148 0.1118 0.188
Brugia malayi ecdysteroid receptor 0.002 0.0019 0.0032
Trichomonas vaginalis tubulin epsilon chain, putative 0.0049 0.0272 0.1356
Onchocerca volvulus Neuropeptide F receptor homolog 0.0148 0.1118 0.1854
Brugia malayi MH2 domain containing protein 0.0265 0.2124 0.3572
Schistosoma mansoni neuropeptide F-like receptor 0.0148 0.1118 0.1299
Toxoplasma gondii FATC domain-containing protein 0.0024 0.0056 0.011
Plasmodium falciparum histone deacetylase, putative 0.0186 0.1452 0.7151
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0148 0.1118 0.1118
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0148 0.1118 0.1118
Onchocerca volvulus 0.0039 0.0189 0.0286
Loa Loa (eye worm) hypothetical protein 0.0148 0.1118 0.188
Onchocerca volvulus 0.0148 0.1118 0.1854
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0027 0.0079 0.0154
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0148 0.1118 0.1118
Leishmania major beta tubulin 0.0049 0.0272 0.1356
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0047 0.025 0.042
Toxoplasma gondii microneme protein, putative 0.0039 0.0189 0.0368
Echinococcus multilocularis sex peptide receptor 0.0148 0.1118 0.1118
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0157 0.1203 0.1398
Brugia malayi Steroid receptor seven-up type 2 0.002 0.0019 0.0032
Loa Loa (eye worm) hypothetical protein 0.002 0.0019 0.0032
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.002 0.0019 0.0022
Trichomonas vaginalis DNA polymerase eta, putative 0.002 0.0021 0.0105
Echinococcus multilocularis neuropeptides capa receptor 0.0148 0.1118 0.1118
Loa Loa (eye worm) hypothetical protein 0.0039 0.0189 0.0317
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0148 0.1118 0.1118
Brugia malayi PAN domain containing protein 0.0039 0.0189 0.0317
Leishmania major DNA polymerase eta, putative 0.002 0.0021 0.0105
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0148 0.1118 0.1118
Onchocerca volvulus 0.0029 0.0098 0.0134
Loa Loa (eye worm) tubulin beta-4 chain 0.0049 0.0272 0.0457
Plasmodium falciparum plasmepsin I 0.0041 0.0201 0.0707
Schistosoma mansoni protein farnesyltransferase subunit beta 0.0037 0.0163 0.019
Echinococcus multilocularis histone deacetylase 6 0.0186 0.1452 0.1452
Onchocerca volvulus 0.0148 0.1118 0.1854
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0064 0.0317
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0251 0.2006 1
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.002 0.0021 0.0105
Echinococcus multilocularis beta tubulin 0.0049 0.0272 0.0272
Loa Loa (eye worm) Smad1 0.0018 0.0004 0.0007
Schistosoma mansoni hypothetical protein 0.0148 0.1118 0.1299
Echinococcus multilocularis neuropeptide s receptor 0.0148 0.1118 0.1118
Plasmodium vivax aspartyl protease, putative 0.0041 0.0201 0.0609
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0148 0.1118 0.1299
Echinococcus granulosus g protein coupled receptor 0.0148 0.1118 0.1118
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0019 0.0032
Schistosoma mansoni hypothetical protein 0.0148 0.1118 0.1299
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0091 0.0635 0.0738
Loa Loa (eye worm) hypothetical protein 0.004 0.019 0.0319
Loa Loa (eye worm) hypothetical protein 0.0148 0.1118 0.188
Schistosoma mansoni biogenic amine receptor 0.0148 0.1118 0.1299
Schistosoma mansoni histone deacetylase 0.0251 0.2006 0.2331
Schistosoma mansoni Smad4 0.0018 0.0004 0.0005
Toxoplasma gondii microneme protein MIC4 0.0039 0.0189 0.0368
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0041 0.0201 0.0234
Loa Loa (eye worm) hypothetical protein 0.0148 0.1118 0.188
Brugia malayi Nuclear hormone receptor family member nhr-40 0.002 0.0019 0.0032
Entamoeba histolytica hypothetical protein 0.007 0.0448 0.2231
Brugia malayi PAN domain containing protein 0.0039 0.0189 0.0317
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0024 0.0056 0.0095
Schistosoma mansoni opsin-like receptor 0.0148 0.1118 0.1299
Echinococcus granulosus neuropeptide FF receptor 2 0.0148 0.1118 0.1118
Brugia malayi Tubulin beta-1 chain 0.0049 0.0272 0.0457
Treponema pallidum sodium- and chloride- dependent transporter 0.0157 0.1203 0.5
Echinococcus granulosus ETS transcription factor Elf 2 0.0021 0.003 0.003
Loa Loa (eye worm) hypothetical protein 0.0148 0.1118 0.188
Onchocerca volvulus 0.0039 0.0189 0.0286
Echinococcus granulosus biogenic amine 5HT receptor 0.0148 0.1118 0.1118
Loa Loa (eye worm) tubulin beta-1 chain 0.0049 0.0272 0.0457
Trichomonas vaginalis geranylgeranyl transferase type I beta subunit, putative 0.0037 0.0163 0.0814
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0148 0.1118 0.1118
Loa Loa (eye worm) hypothetical protein 0.0027 0.0079 0.0133
Echinococcus granulosus neuropeptide s receptor 0.0148 0.1118 0.1118
Brugia malayi PHD-finger family protein 0.0024 0.0057 0.0097
Echinococcus multilocularis neuropeptide receptor 0.0148 0.1118 0.1118
Echinococcus granulosus tubulin beta 4A class IVa 0.0049 0.0272 0.0272
Echinococcus multilocularis ETS domain containing protein Elk 1 0.0021 0.003 0.003
Brugia malayi PAN domain containing protein 0.0039 0.0189 0.0317
Schistosoma mansoni tubulin subunit beta 0.0049 0.0272 0.0316
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0202 0.1583 0.2663
Brugia malayi Tachykinin-like peptides receptor 99D 0.0148 0.1118 0.188
Schistosoma mansoni bromodomain containing protein 0.0062 0.0378 0.0439
Brugia malayi Fli-1 protein 0.044 0.3629 0.6104
Brugia malayi Nuclear hormone receptor family member nhr-41 0.002 0.0019 0.0032
Echinococcus multilocularis histone deacetylase 8 0.0118 0.0863 0.0863
Echinococcus granulosus dna polymerase kappa 0.002 0.0021 0.0021
Trypanosoma brucei beta tubulin 0.0049 0.0272 0.1356
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0027 0.0079 0.0092
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0183 0.142 0.142
Loa Loa (eye worm) hypothetical protein 0.0148 0.1118 0.188
Leishmania major beta tubulin 0.0049 0.0272 0.1356
Schistosoma mansoni transcription factor LCR-F1 0.007 0.0448 0.052
Echinococcus multilocularis Tubulin beta 2C chain 0.0049 0.0272 0.0272
Onchocerca volvulus 0.0148 0.1118 0.1854
Trypanosoma brucei beta tubulin 0.0049 0.0272 0.1356
Giardia lamblia DINP protein human, muc B family 0.002 0.0021 0.0105
Plasmodium falciparum plasmepsin IX 0.0041 0.0201 0.0707
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0053 0.0303 0.0303
Schistosoma mansoni histone deacetylase 4 5 0.0186 0.1452 0.1688
Loa Loa (eye worm) aspartic protease BmAsp-1 0.0041 0.0201 0.0338
Trypanosoma brucei beta tubulin 0.0049 0.0272 0.1356
Echinococcus granulosus beta tubulin 0.0049 0.0272 0.0272
Trypanosoma brucei beta tubulin 0.0049 0.0272 0.1356
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0041 0.0201 0.0234
Trypanosoma brucei DNA polymerase eta, putative 0.002 0.0021 0.0105
Echinococcus multilocularis ETS transcription factor Elf 2 0.0021 0.003 0.003
Brugia malayi sulfakinin receptor protein 0.0148 0.1118 0.188
Loa Loa (eye worm) hypothetical protein 0.0148 0.1118 0.188
Brugia malayi G-protein coupled receptor 0.0148 0.1118 0.188
Trypanosoma brucei histone deacetylase, putative 0.0186 0.1452 0.7242
Toxoplasma gondii subtilisin SUB12 0.0039 0.0189 0.0368
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.002 0.0019 0.0022
Schistosoma mansoni hypothetical protein 0.007 0.0448 0.052
Brugia malayi Serotonin receptor 0.0148 0.1118 0.188
Entamoeba histolytica histone deacetylase, putative 0.0251 0.2006 1
Trypanosoma cruzi histone deacetylase 1, putative 0.0251 0.2006 1
Echinococcus granulosus tm gpcr rhodopsin 0.0148 0.1118 0.1118
Brugia malayi neuropeptide F receptor 0.0148 0.1118 0.188
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0148 0.1118 0.1299
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0786 0.6606 0.6606
Loa Loa (eye worm) hypothetical protein 0.0148 0.1118 0.188
Leishmania major histone deacetylase, putative 0.0251 0.2006 1
Loa Loa (eye worm) PAN domain-containing protein 0.0039 0.0189 0.0317
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0148 0.1118 0.1118
Echinococcus granulosus fetal alzheimer antigen falz 0.0022 0.0038 0.0038
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0021 0.0105
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0202 0.1583 0.2663
Loa Loa (eye worm) hypothetical protein 0.0039 0.0189 0.0317
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0027 0.0079 0.0079
Leishmania major phosphatidylinositol kinase related protein, putative 0.0018 0 0.0001
Loa Loa (eye worm) hypothetical protein 0.0148 0.1118 0.188
Trichomonas vaginalis set domain proteins, putative 0.023 0.1823 0.909
Brugia malayi hypothetical protein 0.0228 0.1813 0.305
Plasmodium vivax hypothetical protein, conserved 0.0027 0.0079 0.0069
Loa Loa (eye worm) hypothetical protein 0.0148 0.1118 0.188
Brugia malayi Ets-domain containing protein 0.0145 0.1094 0.1841
Brugia malayi DNA-binding protein D-ETS-3 0.0021 0.003 0.005
Onchocerca volvulus 0.0039 0.0189 0.0286
Schistosoma mansoni alpha-1 adrenergic receptor 0.0148 0.1118 0.1299
Brugia malayi Dopamine receptor protein 2 0.0148 0.1118 0.188
Loa Loa (eye worm) steroid hormone receptor 0.002 0.0019 0.0032
Toxoplasma gondii beta-1 tubulin, putative 0.0049 0.0272 0.0531
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0019 0.0032
Toxoplasma gondii hypothetical protein 0.0027 0.0079 0.0154
Loa Loa (eye worm) hypothetical protein 0.0157 0.1203 0.2023
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0027 0.0079 0.0092
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0148 0.1118 0.1299
Loa Loa (eye worm) hypothetical protein 0.0046 0.0241 0.0405
Echinococcus multilocularis histone acetyltransferase MYST2 0.0053 0.0303 0.0303
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0021 0.0105
Loa Loa (eye worm) hypothetical protein 0.0202 0.1583 0.2663
Loa Loa (eye worm) hypothetical protein 0.0027 0.0079 0.0133
Schistosoma mansoni amine GPCR 0.0148 0.1118 0.1299
Brugia malayi Pepsin A precursor 0.0041 0.0201 0.0338
Echinococcus granulosus beta tubulin 0.0049 0.0272 0.0272
Toxoplasma gondii hypothetical protein 0.0027 0.0079 0.0154
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0027 0.0079 0.0079
Brugia malayi beta-tubulin, identical 0.0049 0.0272 0.0457
Echinococcus multilocularis G protein coupled receptor 139 0.0148 0.1118 0.1118
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.002 0.0019 0.0032
Trypanosoma brucei histone deacetylase 3 0.0186 0.1452 0.7242
Loa Loa (eye worm) hypothetical protein 0.0148 0.1118 0.188
Echinococcus granulosus rhodopsin orphan GPCR 0.0148 0.1118 0.1118
Echinococcus multilocularis sodium and chloride dependent glycine 0.0027 0.0079 0.0079
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.002 0.0019 0.0022
Schistosoma mansoni sodium/chloride dependent transporter 0.0027 0.0079 0.0092
Loa Loa (eye worm) hypothetical protein 0.0039 0.0189 0.0317
Brugia malayi G protein-coupled receptor 0.0148 0.1118 0.188
Schistosoma mansoni cathepsin D (A01 family) 0.0041 0.0201 0.0234
Onchocerca volvulus 0.0148 0.1118 0.1854
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0029 0.0098 0.0098
Loa Loa (eye worm) hypothetical protein 0.0709 0.5946 1
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0064 0.0398 0.0398
Echinococcus granulosus protein C ets 2 0.0021 0.003 0.003
Plasmodium vivax aspartyl protease, putative 0.0041 0.0201 0.0609
Echinococcus granulosus histone deacetylase 6 0.0186 0.1452 0.1452
Echinococcus granulosus neuropeptide receptor 0.0148 0.1118 0.1118
Mycobacterium ulcerans DNA polymerase IV 0.002 0.0021 0.5
Plasmodium falciparum plasmepsin II 0.0041 0.0201 0.0707
Plasmodium falciparum plasmepsin V 0.0041 0.0201 0.0707
Toxoplasma gondii PAN domain-containing protein 0.0039 0.0189 0.0368
Loa Loa (eye worm) PAN domain-containing protein 0.0039 0.0189 0.0317
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0027 0.0079 0.0092
Schistosoma mansoni biogenic amine receptor 0.0148 0.1118 0.1299
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0148 0.1118 0.188
Onchocerca volvulus 0.023 0.1823 0.3044
Echinococcus granulosus rhodopsin orphan GPCR 0.0148 0.1118 0.1118
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.002 0.0019 0.0032
Echinococcus multilocularis dro:myosuppressin receptor 0.0148 0.1118 0.1118
Plasmodium vivax plasmepsin V, putative 0.0041 0.0201 0.0609
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0148 0.1118 0.1299
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0148 0.1118 0.1118
Trichomonas vaginalis tubulin, putative 0.0049 0.0272 0.1356
Echinococcus granulosus histone deacetylase 1 0.0251 0.2006 0.2006
Brugia malayi Bromodomain containing protein 0.0073 0.0476 0.0801
Loa Loa (eye worm) hypothetical protein 0.002 0.0019 0.0032
Leishmania major beta tubulin 0.0049 0.0272 0.1356
Echinococcus granulosus protein farnesyltransferase subunit beta 0.0037 0.0163 0.0163
Loa Loa (eye worm) hypothetical protein 0.0027 0.0079 0.0133
Echinococcus granulosus neuropeptides capa receptor 0.0148 0.1118 0.1118
Echinococcus granulosus peptide allatostatin:somatostatin 0.0148 0.1118 0.1118
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0018 0 0.0001
Onchocerca volvulus 0.0039 0.0189 0.0286
Echinococcus multilocularis smad 0.0018 0.0004 0.0004
Schistosoma mansoni histone deacetylase hda2 0.0192 0.1504 0.1748
Brugia malayi Prenyltransferase and squalene oxidase repeat family protein 0.0037 0.0163 0.0274
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0148 0.1118 0.1854
Loa Loa (eye worm) hypothetical protein 0.0148 0.1118 0.188
Toxoplasma gondii beta tubulin 0.0049 0.0272 0.0531
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.002 0.0019 0.0032
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0021 0.0105
Toxoplasma gondii PAN domain-containing protein 0.0039 0.0189 0.0368
Schistosoma mansoni growth hormone secretagogue receptor 0.0148 0.1118 0.1299
Schistosoma mansoni terminal deoxycytidyl transferase 0.002 0.0021 0.0024
Brugia malayi Histone deacetylase family protein 0.0186 0.1452 0.2443
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0027 0.0079 0.5
Loa Loa (eye worm) prenyltransferase and squalene oxidase repeat family protein 0.0037 0.0163 0.0274
Schistosoma mansoni neuropeptide receptor 0.0148 0.1118 0.1299
Echinococcus multilocularis Tubulin beta 2C chain 0.0049 0.0272 0.0272
Echinococcus multilocularis ETS transcription factor Elf 1 0.0021 0.003 0.003
Loa Loa (eye worm) hypothetical protein 0.0148 0.1118 0.188
Echinococcus multilocularis ETS transcription factor Elf 5 0.0021 0.003 0.003
Echinococcus multilocularis ewsr:fli fusion protein type 0.0021 0.003 0.003
Leishmania major histone deacetylase, putative 0.0251 0.2006 1
Loa Loa (eye worm) hypothetical protein 0.002 0.0019 0.0032
Loa Loa (eye worm) hypothetical protein 0.0148 0.1118 0.188
Echinococcus granulosus g-protein coupled receptor 0.0148 0.1118 0.1118
Loa Loa (eye worm) hypothetical protein 0.0027 0.0079 0.0133
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.0041 0.0201 0.0201
Schistosoma mansoni tubulin subunit beta 0.0049 0.0272 0.0316
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0148 0.1118 0.1118
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.002 0.0019 0.0022
Brugia malayi Smad1 0.0018 0.0004 0.0007
Echinococcus granulosus histone deacetylase 6 0.0192 0.1504 0.1504
Echinococcus granulosus Tubulin beta 2C chain 0.0049 0.0272 0.0272
Onchocerca volvulus 0.0039 0.0189 0.0286
Loa Loa (eye worm) MH2 domain-containing protein 0.0265 0.2124 0.3572
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0029 0.0098 0.0114
Loa Loa (eye worm) hypothetical protein 0.0148 0.1118 0.188
Brugia malayi MH2 domain containing protein 0.0018 0.0004 0.0007
Schistosoma mansoni hypothetical protein 0.002 0.0022 0.0025
Toxoplasma gondii hypothetical protein 0.0039 0.0189 0.0368
Schistosoma mansoni retinoic acid receptor RXR 0.002 0.0019 0.0022
Echinococcus multilocularis fmrfamide receptor 0.0148 0.1118 0.1118
Loa Loa (eye worm) hypothetical protein 0.0148 0.1118 0.188
Leishmania major beta tubulin 0.0049 0.0272 0.1356
Loa Loa (eye worm) PAN domain-containing protein 0.0039 0.0189 0.0317
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0148 0.1118 0.188
Echinococcus multilocularis serotonin transporter 0.0157 0.1203 0.1203
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.0041 0.0201 0.0201
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0046 0.0241 0.028
Schistosoma mansoni nuclear hormone receptor 0.002 0.0019 0.0022
Trypanosoma cruzi histone deacetylase, putative 0.0118 0.0863 0.4302
Echinococcus multilocularis G-protein coupled receptor, putative 0.0148 0.1118 0.1118
Trichomonas vaginalis geranylgeranyl transferase type beta subunit, putative 0.0037 0.0163 0.0814
Onchocerca volvulus 0.0148 0.1118 0.1854
Echinococcus granulosus rhodopsin orphan GPCR 0.0148 0.1118 0.1118
Loa Loa (eye worm) hypothetical protein 0.0148 0.1118 0.188
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0022 0.0038 0.0044
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0148 0.1118 0.1299
Onchocerca volvulus 0.0041 0.0201 0.0307
Echinococcus multilocularis serotonin receptor 0.0148 0.1118 0.1118
Brugia malayi PAN domain containing protein 0.0039 0.0189 0.0317
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0027 0.0079 0.0133
Brugia malayi nuclear hormone receptor 0.002 0.0019 0.0032
Loa Loa (eye worm) histone deacetylase 3 0.0251 0.2006 0.3373
Onchocerca volvulus 0.0148 0.1118 0.1854
Trypanosoma cruzi DNA polymerase eta, putative 0.002 0.0021 0.0105
Onchocerca volvulus 0.0148 0.1118 0.1854
Onchocerca volvulus 0.0148 0.1118 0.1854
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0148 0.1118 0.1118
Toxoplasma gondii PAN domain-containing protein 0.0613 0.512 1
Loa Loa (eye worm) hypothetical protein 0.0039 0.0189 0.0317
Onchocerca volvulus 0.0027 0.0079 0.0102
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0021 0.0105
Giardia lamblia Beta tubulin 0.0049 0.0272 0.1356
Entamoeba histolytica hypothetical protein 0.007 0.0448 0.2231
Loa Loa (eye worm) hypothetical protein 0.0041 0.0201 0.0338
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.002 0.0021 0.0021
Onchocerca volvulus 0.0047 0.025 0.039
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0053 0.0303 0.0303
Onchocerca volvulus 0.0148 0.1118 0.1854
Brugia malayi latrophilin 2 splice variant baaae 0.0138 0.1035 0.174
Loa Loa (eye worm) melatonin receptor type 1A 0.0148 0.1118 0.188
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0027 0.0079 0.0079
Brugia malayi neuropeptide F receptor 0.0148 0.1118 0.188
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0041 0.0201 0.0234
Brugia malayi Nuclear hormone receptor family member nhr-1 0.002 0.0019 0.0032
Schistosoma mansoni cathepsin D (A01 family) 0.0041 0.0201 0.0234
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0064 0.0317
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0148 0.1118 0.1299
Loa Loa (eye worm) hypothetical protein 0.0037 0.017 0.0286
Brugia malayi RE15519p 0.0148 0.1118 0.188
Brugia malayi Nuclear hormone receptor family member nhr-31 0.002 0.0019 0.0032
Brugia malayi steroid hormone receptor 0.002 0.0019 0.0032
Schistosoma mansoni tubulin subunit beta 0.0049 0.0272 0.0316
Echinococcus multilocularis rhodopsin orphan GPCR 0.0148 0.1118 0.1118
Loa Loa (eye worm) PAN domain-containing protein 0.0039 0.0189 0.0317
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0029 0.0098 0.0192
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0091 0.0635 0.0635
Brugia malayi GnHR receptor homolog 0.0148 0.1118 0.188
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0091 0.0635 0.0635
Echinococcus multilocularis serine protein kinase ATM 0.0024 0.0056 0.0056
Onchocerca volvulus 0.0039 0.0189 0.0286
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.002 0.0019 0.0032
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0091 0.0635 0.1068
Brugia malayi Nuclear hormone receptor family member nhr-3 0.002 0.0019 0.0032
Schistosoma mansoni sodium/chloride dependent transporter 0.0157 0.1203 0.1398
Brugia malayi PAN domain containing protein 0.0039 0.0189 0.0317
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0064 0.0398 0.0398
Schistosoma mansoni smad 0.0018 0.0004 0.0005
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.002 0.0019 0.0019
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0027 0.0079 0.0133
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0058 0.0348 0.0348
Schistosoma mansoni amine GPCR 0.0148 0.1118 0.1299
Echinococcus granulosus serine protein kinase ATM 0.0024 0.0056 0.0056
Loa Loa (eye worm) latrophilin receptor protein 2 0.0064 0.0398 0.0669
Plasmodium falciparum protein farnesyltransferase subunit beta 0.0037 0.0163 0.0513
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0021 0.0105
Schistosoma mansoni histamine h1 receptor 0.0148 0.1118 0.1299
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0027 0.0079 0.0079
Schistosoma mansoni steroid hormone receptor ad4bp 0.002 0.0019 0.0022
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0183 0.142 0.142
Echinococcus granulosus neuropeptide Y receptor 0.0148 0.1118 0.1118
Echinococcus granulosus zinc finger protein 0.0019 0.0013 0.0013
Trichomonas vaginalis histone deacetylase, putative 0.0251 0.2006 1
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0027 0.0079 0.0079
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.002 0.0021 0.0035
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.002 0.0021 0.0105
Toxoplasma gondii microneme protein MIC17C 0.0039 0.0189 0.0368
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0148 0.1118 0.1299
Echinococcus multilocularis neuropeptide Y receptor 0.0148 0.1118 0.1118
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0041 0.0201 0.0234
Trichomonas vaginalis tubulin beta chain, putative 0.0049 0.0272 0.1356
Schistosoma mansoni myosin xvIII 0.0148 0.1118 0.1299
Toxoplasma gondii microneme protein MIC17A 0.0039 0.0189 0.0368
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0148 0.1118 0.1299
Echinococcus granulosus ETS transcription factor Elf 5 0.0021 0.003 0.003
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0148 0.1118 0.1299
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0027 0.0079 0.0154
Plasmodium falciparum amino acid transporter, putative 0.0027 0.0079 0.008
Trichomonas vaginalis tubulin gamma chain, putative 0.0049 0.0272 0.1356
Schistosoma mansoni hypothetical protein 0.0064 0.0398 0.0463
Echinococcus granulosus mothers against decapentaplegic 5 0.0018 0.0004 0.0004
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0251 0.2006 1
Plasmodium vivax aspartyl protease, putative 0.0041 0.0201 0.0609
Loa Loa (eye worm) hypothetical protein 0.0148 0.1118 0.188
Echinococcus multilocularis rhodopsin orphan GPCR 0.0148 0.1118 0.1118
Loa Loa (eye worm) hypothetical protein 0.0148 0.1118 0.188
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.007 0.0448 0.0448
Echinococcus granulosus tm gpcr rhodopsin 0.0148 0.1118 0.1118
Brugia malayi Eukaryotic aspartyl protease family protein 0.0041 0.0201 0.0338
Onchocerca volvulus 0.0148 0.1118 0.1854
Plasmodium falciparum plasmepsin X 0.0041 0.0201 0.0707
Echinococcus granulosus rhodopsin orphan GPCR 0.0148 0.1118 0.1118
Echinococcus granulosus neuropeptides capa receptor 0.0148 0.1118 0.1118
Loa Loa (eye worm) hypothetical protein 0.0148 0.1118 0.188
Schistosoma mansoni hypothetical protein 0.0064 0.0398 0.0463
Brugia malayi Dopamine receptor protein 1 0.0148 0.1118 0.188
Trypanosoma cruzi protein farnesyltransferase, putative 0.0037 0.0163 0.0814
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.0041 0.0201 0.1002
Echinococcus multilocularis rhodopsin orphan GPCR 0.0148 0.1118 0.1118
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0021 0.0105
Echinococcus granulosus FTZ F1 alpha 0.002 0.0019 0.0019
Schistosoma mansoni hypothetical protein 0.0021 0.003 0.0035
Loa Loa (eye worm) beta-tubulin 0.0049 0.0272 0.0457
Brugia malayi hypothetical protein 0.0148 0.1118 0.188
Echinococcus multilocularis dna polymerase eta 0.002 0.0021 0.0021
Echinococcus multilocularis sodium and chloride dependent glycine 0.0027 0.0079 0.0079
Loa Loa (eye worm) aspartyl protease 6 0.0041 0.0201 0.0338
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0145 0.1094 0.1841
Echinococcus multilocularis GPCR, family 2 0.0064 0.0398 0.0398
Echinococcus granulosus neuropeptide receptor 0.0148 0.1118 0.1118
Leishmania major beta tubulin 0.0049 0.0272 0.1356
Entamoeba histolytica hypothetical protein 0.007 0.0448 0.2231
Trypanosoma cruzi lanosterol synthase, putative 0.004 0.0194 0.0966
Loa Loa (eye worm) hypothetical protein 0.0053 0.0303 0.051
Echinococcus granulosus 7tm_1 domain containing protein 0.0148 0.1118 0.1118
Echinococcus granulosus Tubulin beta 2C chain 0.0049 0.0272 0.0272
Onchocerca volvulus 0.0148 0.1118 0.1854
Leishmania major beta tubulin 0.0049 0.0272 0.1356
Loa Loa (eye worm) hypothetical protein 0.0148 0.1118 0.188
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0021 0.0027 0.0136
Schistosoma mansoni biogenic amine (5HT) receptor 0.0148 0.1118 0.1299
Echinococcus granulosus alpha 1A adrenergic receptor 0.0148 0.1118 0.1118
Loa Loa (eye worm) hypothetical protein 0.0148 0.1118 0.188
Echinococcus granulosus histone acetyltransferase MYST2 0.0053 0.0303 0.0303
Brugia malayi hypothetical protein 0.0148 0.1118 0.188
Schistosoma mansoni amine GPCR 0.0148 0.1118 0.1299
Loa Loa (eye worm) hypothetical protein 0.0075 0.049 0.0825
Giardia lamblia Histone deacetylase 0.0251 0.2006 1
Schistosoma mansoni histone deacetylase 0.0251 0.2006 0.2331
Leishmania major beta tubulin 0.0049 0.0272 0.1356
Loa Loa (eye worm) hypothetical protein 0.0148 0.1118 0.188
Brugia malayi Ets-domain containing protein 0.0021 0.003 0.005
Entamoeba histolytica protein farnesyltransferase beta subunit, putative 0.0037 0.0163 0.0814
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0027 0.0079 0.0092
Echinococcus multilocularis histone deacetylase 0.0186 0.1452 0.1452
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0029 0.0098 0.0114
Schistosoma mansoni adenoreceptor 0.0148 0.1118 0.1299
Loa Loa (eye worm) hypothetical protein 0.0148 0.1118 0.188
Loa Loa (eye worm) hypothetical protein 0.0157 0.1203 0.2023
Brugia malayi aspartic protease BmAsp-1, identical 0.0041 0.0201 0.0338
Loa Loa (eye worm) histone deacetylase 1 0.0251 0.2006 0.3373
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0148 0.1118 0.1299
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0019 0.0032
Echinococcus multilocularis neuropeptide FF receptor 2 0.0148 0.1118 0.1118
Loa Loa (eye worm) hypothetical protein 0.002 0.0019 0.0032
Echinococcus multilocularis rhodopsin orphan GPCR 0.0148 0.1118 0.1118
Echinococcus granulosus fmrfamide receptor 0.0148 0.1118 0.1118
Brugia malayi putative neuropeptide receptor 0.0148 0.1118 0.188
Plasmodium falciparum histone deacetylase 2 0.0186 0.1452 0.7151
Leishmania major beta tubulin 0.0049 0.0272 0.1356
Entamoeba histolytica hypothetical protein 0.007 0.0448 0.2231
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0091 0.0635 0.1068
Loa Loa (eye worm) hypothetical protein 0.0027 0.0079 0.0133
Toxoplasma gondii histone deacetylase HDAC3 0.0251 0.2006 0.3918
Echinococcus multilocularis rhodopsin orphan GPCR 0.0148 0.1118 0.1118
Leishmania major beta tubulin 0.0049 0.0272 0.1356
Plasmodium falciparum plasmepsin VI 0.0041 0.0201 0.0707
Echinococcus granulosus sex peptide receptor 0.0148 0.1118 0.1118
Schistosoma mansoni RAR-like nuclear receptor 0.002 0.0019 0.0022
Echinococcus granulosus histone deacetylase 0.0186 0.1452 0.1452
Toxoplasma gondii PAN domain-containing protein 0.0613 0.512 1
Plasmodium vivax histone deacetylase, putative 0.0287 0.2319 1
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.002 0.0019 0.0019
Plasmodium vivax farnesyltransferase beta subunit, putative 0.0037 0.0163 0.0441
Loa Loa (eye worm) histone deacetylase 0.0186 0.1452 0.2443
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0019 0.0019
Entamoeba histolytica tubulin family protein 0.0049 0.0272 0.1356
Echinococcus multilocularis neuropeptide Y receptor 0.0148 0.1118 0.1118
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.0035
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0041 0.0201 0.0234
Brugia malayi Histone deacetylase family protein 0.0186 0.1452 0.2443
Brugia malayi photoreceptor-specific nuclear receptor 0.002 0.0019 0.0032
Loa Loa (eye worm) hypothetical protein 0.0148 0.1118 0.188
Echinococcus multilocularis orexin receptor type 2 0.0148 0.1118 0.1118
Echinococcus multilocularis beta tubulin 0.0049 0.0272 0.0272
Loa Loa (eye worm) hypothetical protein 0.0148 0.1118 0.188
Brugia malayi histone deacetylase 3 (HD3) 0.0251 0.2006 0.3373
Loa Loa (eye worm) hypothetical protein 0.0148 0.1118 0.188
Echinococcus multilocularis g protein coupled receptor 0.0148 0.1118 0.1118
Toxoplasma gondii eukaryotic aspartyl protease superfamily protein 0.0041 0.0201 0.0392
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0027 0.0079 0.0154
Schistosoma mansoni opsin-like receptor 0.0148 0.1118 0.1299
Onchocerca volvulus 0.0148 0.1118 0.1854
Onchocerca volvulus Histone deacetylase 10 homolog 0.0118 0.0863 0.1424
Schistosoma mansoni amine GPCR 0.0148 0.1118 0.1299
Echinococcus granulosus histone deacetylase 3 0.0251 0.2006 0.2006
Loa Loa (eye worm) solute carrier family 6 member 4 0.0157 0.1203 0.2023
Leishmania major beta tubulin 0.0049 0.0272 0.1356
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0148 0.1118 0.1299
Echinococcus multilocularis Smad4 0.0018 0.0004 0.0004
Schistosoma mansoni coup transcription factor 0.002 0.0019 0.0022
Loa Loa (eye worm) hypothetical protein 0.0148 0.1118 0.188
Schistosoma mansoni neuropeptide receptor 0.0148 0.1118 0.1299
Schistosoma mansoni smad1 5 8 and 0.0018 0.0004 0.0005
Onchocerca volvulus 0.0046 0.0248 0.0386
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0148 0.1118 0.1118
Schistosoma mansoni hypothetical protein 0.0148 0.1118 0.1299
Trypanosoma brucei histone deacetylase 4 0.0186 0.1452 0.7242
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0021 0.0105
Plasmodium falciparum histone deacetylase 1 0.0251 0.2006 1
Loa Loa (eye worm) hypothetical protein 0.0148 0.1118 0.188
Schistosoma mansoni sodium-dependent amino acid transporter 0.0027 0.0079 0.0092
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0148 0.1118 0.188
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.002 0.0019 0.0019
Loa Loa (eye worm) D-ets-2 protein 0.0021 0.003 0.005
Brugia malayi Calcitonin receptor-like protein seb-1 0.0202 0.1583 0.2663
Schistosoma mansoni neuropeptide receptor 0.0148 0.1118 0.1299
Brugia malayi Dopamine receptor 0.0148 0.1118 0.188
Loa Loa (eye worm) hypothetical protein 0.0148 0.1118 0.188
Toxoplasma gondii aspartyl protease 0.0041 0.0201 0.0392
Plasmodium vivax amine transporter, putative 0.0027 0.0079 0.0069
Schistosoma mansoni opsin-like receptor 0.0148 0.1118 0.1299
Loa Loa (eye worm) hypothetical protein 0.002 0.0019 0.0032
Trichomonas vaginalis tubulin alpha chain, putative 0.0049 0.0272 0.1356
Schistosoma mansoni Tr4/Tr2 (homologue) 0.002 0.0019 0.0022
Echinococcus granulosus hypothetical protein 0.0148 0.1118 0.1118
Echinococcus multilocularis tubulin, beta 4A class IVa 0.0049 0.0272 0.0272
Echinococcus granulosus g protein coupled receptor 0.0148 0.1118 0.1118
Leishmania major hypothetical protein, conserved 0.0025 0.0064 0.0317
Echinococcus granulosus biogenic amine 5HT receptor 0.0148 0.1118 0.1118
Brugia malayi hypothetical protein 0.0041 0.0201 0.0338
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0027 0.0079 0.0133
Echinococcus granulosus serotonin receptor 0.0148 0.1118 0.1118
Loa Loa (eye worm) DNA-binding protein D-ETS-3 0.0021 0.003 0.005
Loa Loa (eye worm) hypothetical protein 0.0148 0.1118 0.188
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0021 0.0105
Onchocerca volvulus Phospholipase A2 homolog 0.0709 0.5946 1
Schistosoma mansoni tubulin subunit beta 0.0049 0.0272 0.0316
Echinococcus multilocularis FTZ F1 alpha 0.002 0.0019 0.0019
Brugia malayi hypothetical protein 0.0148 0.1118 0.188
Echinococcus multilocularis protein farnesyltransferase subunit beta 0.0037 0.0163 0.0163
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0251 0.2006 1
Loa Loa (eye worm) hypothetical protein 0.0039 0.0189 0.0317
Schistosoma mansoni hypothetical protein 0.0064 0.0398 0.0463
Leishmania major farnesyltransferase beta subunit 0.0037 0.0163 0.0814
Loa Loa (eye worm) hypothetical protein 0.0148 0.1118 0.188
Leishmania major beta tubulin 0.0049 0.0272 0.1356
Toxoplasma gondii histone deacetylase HDAC1 0.0186 0.1452 0.2837
Brugia malayi ImpB/MucB/SamB family protein 0.002 0.0021 0.0035
Echinococcus multilocularis tachykinin peptides receptor 99D 0.1181 1 1
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0041 0.0201 0.0234
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0091 0.0635 0.0738
Echinococcus multilocularis ETS transcription factor Elf 2 0.0021 0.003 0.003
Toxoplasma gondii hypothetical protein 0.0039 0.0189 0.0368
Loa Loa (eye worm) hypothetical protein 0.0041 0.0201 0.0338
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0019 0.0019
Brugia malayi MH1 domain containing protein 0.0018 0.0004 0.0007
Echinococcus multilocularis histone deacetylase 1 0.0251 0.2006 0.2006
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0148 0.1118 0.1118
Trichomonas vaginalis histone deacetylase, putative 0.0251 0.2006 1
Leishmania major beta tubulin 0.0049 0.0272 0.1356
Trypanosoma cruzi lanosterol synthase, putative 0.004 0.0194 0.0966
Loa Loa (eye worm) hypothetical protein 0.0148 0.1118 0.188
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0148 0.1118 0.1299
Brugia malayi hypothetical protein 0.0148 0.1118 0.188
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0019 0.0019
Echinococcus multilocularis thyroid hormone receptor alpha 0.002 0.0019 0.0019
Echinococcus multilocularis g protein coupled receptor 0.0148 0.1118 0.1118
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0019 0.0032
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0056 0.0281
Echinococcus granulosus 7TM GPCR rhodopsin 0.0148 0.1118 0.1118
Loa Loa (eye worm) hypothetical protein 0.0124 0.0914 0.1537
Echinococcus multilocularis neuropeptides capa receptor 0.0148 0.1118 0.1118
Trypanosoma brucei histone deacetylase 2 0.0118 0.0863 0.4302
Loa Loa (eye worm) hypothetical protein 0.0157 0.1203 0.2023
Trypanosoma cruzi histone deacetylase, putative 0.0186 0.1452 0.7242
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0019 0.0032
Echinococcus granulosus histone deacetylase 6 0.0186 0.1452 0.1452
Schistosoma mansoni zinc finger protein 0.0019 0.0013 0.0015
Schistosoma mansoni neuropeptide receptor 0.0148 0.1118 0.1299
Echinococcus granulosus Tubulin beta 2C chain 0.0049 0.0272 0.0272
Echinococcus multilocularis tubulin subunit beta 0.0049 0.0272 0.0272
Brugia malayi PAN domain containing protein 0.0039 0.0189 0.0317
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0148 0.1118 0.188
Echinococcus multilocularis histone deacetylase 3 0.0251 0.2006 0.2006
Loa Loa (eye worm) aspartic protease BmAsp-2 0.0041 0.0201 0.0338
Echinococcus granulosus Smad4 0.0018 0.0004 0.0004
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0148 0.1118 0.1118
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0064 0.0398 0.0669
Trichomonas vaginalis histone deacetylase, putative 0.0251 0.2006 1
Toxoplasma gondii PAN domain-containing protein 0.0039 0.0189 0.0368
Echinococcus granulosus retinoic acid receptor rxr beta a 0.002 0.0019 0.0019
Trypanosoma cruzi histone deacetylase, putative 0.0118 0.0863 0.4302
Echinococcus multilocularis GA binding protein alpha chain 0.0145 0.1094 0.1094
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0027 0.0079 0.0092
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0021 0.0105
Schistosoma mansoni smad1 5 8 and 0.0018 0.0004 0.0005
Schistosoma mansoni sex comb on midleg homolog 0.0046 0.0248 0.0288
Onchocerca volvulus 0.0039 0.0189 0.0286
Brugia malayi nuclear receptor NHR-88 0.002 0.0019 0.0032
Onchocerca volvulus 0.0039 0.0189 0.0286
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0091 0.0635 0.0635
Brugia malayi Pre-SET motif family protein 0.0202 0.1583 0.2663
Loa Loa (eye worm) hypothetical protein 0.0041 0.0201 0.0338
Brugia malayi hypothetical protein 0.0025 0.0064 0.0107
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0046 0.0248 0.0386
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0064 0.0124
Brugia malayi Nuclear hormone receptor family member nhr-49 0.002 0.0019 0.0032
Plasmodium falciparum plasmepsin VIII, putative 0.0041 0.0201 0.0707
Loa Loa (eye worm) hypothetical protein 0.0041 0.0206 0.0346
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0034 0.0138 0.016
Schistosoma mansoni sex comb on midleg homolog 0.0046 0.0248 0.0288
Brugia malayi aspartic protease BmAsp-2, identical 0.0041 0.0201 0.0338
Loa Loa (eye worm) hypothetical protein 0.0148 0.1118 0.188
Mycobacterium ulcerans DNA polymerase IV 0.002 0.0021 0.5
Brugia malayi hypothetical protein 0.0148 0.1118 0.188
Echinococcus multilocularis dna polymerase kappa 0.002 0.0021 0.0021
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0021 0.0105
Loa Loa (eye worm) G-protein coupled receptor 0.0148 0.1118 0.188
Echinococcus granulosus histone lysine methyltransferase setb 0.0046 0.0241 0.0241
Brugia malayi mbt repeat family protein 0.0046 0.0248 0.0417
Schistosoma mansoni histone deacetylase hda2 0.0118 0.0863 0.1003
Echinococcus granulosus TGF beta signal transducer SmadC 0.0018 0.0004 0.0004
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0021 0.0105
Echinococcus granulosus histone deacetylase 8 0.0118 0.0863 0.0863
Echinococcus granulosus ecdysone induced protein 78C 0.002 0.0019 0.0019
Plasmodium vivax aspartyl proteinase, putative 0.0041 0.0201 0.0609
Echinococcus multilocularis g protein coupled receptor 0.0148 0.1118 0.1118
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0035 0.015 0.015
Echinococcus multilocularis protein C ets 2 0.0021 0.003 0.003
Echinococcus multilocularis rhodopsin orphan GPCR 0.0148 0.1118 0.1118
Plasmodium falciparum transporter, putative 0.0027 0.0079 0.008
Loa Loa (eye worm) hypothetical protein 0.0118 0.0863 0.1451
Brugia malayi follicle stimulating hormone receptor 0.0148 0.1118 0.188
Echinococcus granulosus tm gpcr rhodopsin 0.0148 0.1118 0.1118
Schistosoma mansoni hypothetical protein 0.0282 0.2272 0.2641
Onchocerca volvulus 0.0157 0.1203 0.1998
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0021 0.0105
Trichomonas vaginalis tubulin epsilon chain, putative 0.0049 0.0272 0.1356
Echinococcus granulosus dro:myosuppressin receptor 0.0148 0.1118 0.1118
Loa Loa (eye worm) hypothetical protein 0.0027 0.0079 0.0133
Echinococcus granulosus ETS transcription factor Elf 1 0.0021 0.003 0.003
Trypanosoma cruzi beta tubulin, putative 0.0049 0.0272 0.1356
Brugia malayi histone deacetylase 11 0.0287 0.2319 0.39
Echinococcus granulosus SAM and MBT domain containing protein 0.0046 0.0248 0.0248
Brugia malayi histone deacetylase 1 (HD1) 0.0251 0.2006 0.3373
Echinococcus granulosus allatostatin A receptor 0.0148 0.1118 0.1118
Brugia malayi MH2 domain containing protein 0.0018 0.0004 0.0007
Echinococcus multilocularis fmrfamide receptor 0.0148 0.1118 0.1118
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0157 0.1203 0.2023
Entamoeba histolytica deoxycytidyl transferase, putative 0.002 0.0021 0.0105
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0041 0.0201 0.0234
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0027 0.0079 0.0133
Brugia malayi PAN domain containing protein 0.0039 0.0189 0.0317
Brugia malayi hypothetical protein 0.0148 0.1118 0.188
Brugia malayi hypothetical protein 0.0148 0.1118 0.188
Onchocerca volvulus 0.0148 0.1118 0.1854
Onchocerca volvulus 0.0148 0.1118 0.1854
Loa Loa (eye worm) hypothetical protein 0.0148 0.1118 0.188
Schistosoma mansoni smad1 5 8 and 0.0018 0.0004 0.0005
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0148 0.1118 0.188
Leishmania major beta tubulin 0.0049 0.0272 0.1356
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0064 0.0398 0.0398
Onchocerca volvulus 0.0039 0.0189 0.0286
Schistosoma mansoni histone deacetylase 4 5 0.0186 0.1452 0.1688
Schistosoma mansoni memapsin-2 (A01 family) 0.1018 0.8605 1
Brugia malayi Bromodomain containing protein 0.0037 0.0169 0.0285
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0148 0.1118 0.1299
Loa Loa (eye worm) hypothetical protein 0.0251 0.2006 0.3373
Schistosoma mansoni elf1 0.0021 0.003 0.0035
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0021 0.0105
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0035 0.015 0.015
Trypanosoma brucei protein farnesyltransferase beta subunit 0.0037 0.0163 0.0814
Schistosoma mansoni hypothetical protein 0.0064 0.0398 0.0463
Echinococcus granulosus sodium and chloride dependent glycine 0.0027 0.0079 0.0079
Brugia malayi mbt repeat family protein 0.0046 0.0248 0.0417
Brugia malayi hypothetical protein 0.0148 0.1118 0.188
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0064 0.0398 0.0398
Loa Loa (eye worm) G-protein coupled receptor 0.0148 0.1118 0.188
Loa Loa (eye worm) histone deacetylase 11 0.0287 0.2319 0.39
Loa Loa (eye worm) hypothetical protein 0.0148 0.1118 0.188
Loa Loa (eye worm) hypothetical protein 0.0148 0.1118 0.188
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0148 0.1118 0.188
Echinococcus granulosus GA binding protein alpha chain 0.0145 0.1094 0.1094
Loa Loa (eye worm) hypothetical protein 0.0021 0.003 0.005
Brugia malayi transcription factor E74 isoform 0.0021 0.003 0.005
Toxoplasma gondii histone deacetylase HDAC2 0.0251 0.2006 0.3918
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0022 0.0038 0.0038
Trichomonas vaginalis histone deacetylase, putative 0.0251 0.2006 1
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0041 0.0201 0.0234
Echinococcus granulosus somatostatin receptor 0.0148 0.1118 0.1118
Loa Loa (eye worm) MBCTL1 0.0053 0.0303 0.051
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.0041 0.0201 0.0392
Echinococcus granulosus sodium and chloride dependent glycine 0.0027 0.0079 0.0079
Loa Loa (eye worm) tubulin beta chain 0.0049 0.0272 0.0457
Echinococcus granulosus ewsr:fli fusion protein type 0.0021 0.003 0.003
Toxoplasma gondii microneme protein MIC17B 0.0039 0.0189 0.0368
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.002 0.0019 0.0032
Leishmania major DNA polymerase kappa, putative 0.002 0.0021 0.0105
Toxoplasma gondii PAN/Apple domain-containing protein 0.0039 0.0189 0.0368
Loa Loa (eye worm) hypothetical protein 0.0027 0.0079 0.0133
Loa Loa (eye worm) hypothetical protein 0.0148 0.1118 0.188
Schistosoma mansoni neuropeptide F-like receptor 0.0148 0.1118 0.1299
Brugia malayi G-protein coupled receptor 0.0148 0.1118 0.188
Echinococcus granulosus rhodopsin orphan GPCR 0.0148 0.1118 0.1118
Plasmodium falciparum tubulin beta chain 0.0049 0.0272 0.1073
Loa Loa (eye worm) hypothetical protein 0.0138 0.1035 0.174
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0148 0.1118 0.1299
Loa Loa (eye worm) hypothetical protein 0.0148 0.1118 0.188
Echinococcus multilocularis histone deacetylase 7 0.0186 0.1452 0.1452
Loa Loa (eye worm) hypothetical protein 0.0064 0.0398 0.0669
Leishmania major beta tubulin 0.0049 0.0272 0.1356
Brugia malayi Nuclear hormone receptor family member nhr-14 0.002 0.0019 0.0032
Brugia malayi hypothetical protein 0.0027 0.0079 0.0133
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.0037 0.0163 0.0814
Toxoplasma gondii histone deacetylase HDAC4 0.0287 0.2319 0.453
Schistosoma mansoni sodium/chloride dependent transporter 0.0027 0.0079 0.0092
Plasmodium falciparum plasmepsin III 0.0041 0.0201 0.0707
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0018 0.0004 0.0005
Schistosoma mansoni survival motor neuron protein 0.0047 0.025 0.029
Loa Loa (eye worm) hypothetical protein 0.0148 0.1118 0.188
Echinococcus granulosus Tubulin beta 2C chain 0.0049 0.0272 0.0272
Schistosoma mansoni polyomavirus enhancer activator 3 pea3 0.0021 0.003 0.0035
Brugia malayi Serotonin receptor 0.0148 0.1118 0.188
Brugia malayi putative neuropeptide receptor NPR1 0.0148 0.1118 0.188
Toxoplasma gondii 1,3(4)-beta-glucanase 0.0039 0.0189 0.0368
Trichomonas vaginalis histone deacetylase, putative 0.0251 0.2006 1
Brugia malayi MH1 domain containing protein 0.0018 0.0004 0.0007
Onchocerca volvulus 0.0027 0.0079 0.0102
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.002 0.0019 0.0032
Echinococcus multilocularis histone deacetylase 6 0.0186 0.1452 0.1452
Echinococcus multilocularis Tubulin beta 2C chain 0.0049 0.0272 0.0272
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.007 0.0448 0.0448
Loa Loa (eye worm) PHD-finger family protein 0.002 0.0022 0.0037
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0046 0.0248 0.0288
Loa Loa (eye worm) hypothetical protein 0.0039 0.0189 0.0317
Loa Loa (eye worm) hypothetical protein 0.0039 0.0189 0.0317
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0148 0.1118 0.1299
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.002 0.0019 0.0019
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0148 0.1118 0.188
Echinococcus granulosus serotonin transporter 0.0157 0.1203 0.1203
Loa Loa (eye worm) BEN-1 protein 0.0049 0.0272 0.0457
Echinococcus granulosus survival motor neuron protein 1 0.0228 0.1813 0.1813
Echinococcus multilocularis neuropeptide receptor A26 0.0148 0.1118 0.1118
Schistosoma mansoni histone deacetylase 1 2 3 0.0118 0.0863 0.1003
Trichomonas vaginalis histone deacetylase, putative 0.0251 0.2006 1
Echinococcus multilocularis serotonin receptor 0.0148 0.1118 0.1118
Plasmodium vivax plasmepsin IV, putative 0.0041 0.0201 0.0609
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0089 0.0089
Trypanosoma cruzi histone deacetylase 1, putative 0.0251 0.2006 1
Brugia malayi G protein-coupled receptor F59B2.13 0.0148 0.1118 0.188
Loa Loa (eye worm) serotonin transporter b 0.0157 0.1203 0.2023
Echinococcus multilocularis histone deacetylase 6 0.0192 0.1504 0.1504
Echinococcus multilocularis Tubulin beta 2C chain 0.0049 0.0272 0.0272
Onchocerca volvulus 0.0148 0.1118 0.1854
Brugia malayi PAN domain containing protein 0.0039 0.0189 0.0317
Echinococcus multilocularis neuropeptide receptor 0.0148 0.1118 0.1118
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0018 0.0004 0.0004
Schistosoma mansoni ets 0.0021 0.003 0.0035
Toxoplasma gondii aspartyl protease ASP3 0.0041 0.0201 0.0392
Schistosoma mansoni thyroid hormone receptor 0.002 0.0019 0.0022
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0148 0.1118 0.1118
Schistosoma mansoni tubulin subunit beta 0.0049 0.0272 0.0316
Loa Loa (eye worm) hypothetical protein 0.0046 0.0248 0.0417
Schistosoma mansoni amine GPCR 0.0148 0.1118 0.1299
Onchocerca volvulus 0.0027 0.0079 0.0102
Leishmania major beta tubulin 0.0049 0.0272 0.1356
Schistosoma mansoni tubulin subunit beta 0.0049 0.0272 0.0316
Loa Loa (eye worm) hypothetical protein 0.0148 0.1118 0.188
Echinococcus granulosus dna polymerase eta 0.002 0.0021 0.0021
Brugia malayi Phospholipase A2 family protein 0.0709 0.5946 1
Loa Loa (eye worm) hypothetical protein 0.002 0.0019 0.0032
Loa Loa (eye worm) hypothetical protein 0.0709 0.5946 1
Toxoplasma gondii aspartyl protease ASP1 0.0041 0.0201 0.0392
Brugia malayi Latrophilin receptor protein 2 0.0064 0.0398 0.0669
Brugia malayi Pre-SET motif family protein 0.0029 0.0098 0.0165
Echinococcus multilocularis ecdysone induced protein 78C 0.002 0.0019 0.0019
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.002 0.0019 0.0032
Echinococcus granulosus tubulin beta 1 chain 0.0049 0.0272 0.0272
Plasmodium vivax conserved Plasmodium protein, unknown function 0.0027 0.0078 0.0064
Brugia malayi Histone deacetylase 1 0.0251 0.2006 0.3373
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0053 0.0303 0.051
Toxoplasma gondii prenyltransferase and squalene oxidase repeat-containing protein 0.0037 0.0163 0.0319
Brugia malayi PAN domain containing protein 0.0039 0.0189 0.0317
Toxoplasma gondii PAN domain-containing protein 0.0039 0.0189 0.0368
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0058 0.0348 0.0348
Loa Loa (eye worm) ets-domain-containing protein 0.0021 0.003 0.005
Brugia malayi ORL1-like opioid receptor 0.0148 0.1118 0.188
Schistosoma mansoni biogenic amine (5HT) receptor 0.0148 0.1118 0.1299
Brugia malayi hypothetical protein 0.0148 0.1118 0.188
Loa Loa (eye worm) hypothetical protein 0.0228 0.1813 0.305
Loa Loa (eye worm) MH1 domain-containing protein 0.0018 0.0004 0.0007
Plasmodium vivax aspartyl proteinase, putative 0.0041 0.0201 0.0609
Echinococcus multilocularis allatostatin A receptor 0.0148 0.1118 0.1118
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0046 0.0241 0.0241
Echinococcus multilocularis Tubulin beta 2C chain 0.0049 0.0272 0.0272
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0202 0.1583 0.2663
Echinococcus multilocularis survival motor neuron protein 1 0.0228 0.1813 0.1813
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0148 0.1118 0.1299
Schistosoma mansoni DNA polymerase eta 0.002 0.0021 0.0024
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0148 0.1118 0.1118
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0019 0.0032
Schistosoma mansoni hypothetical protein 0.0047 0.025 0.029
Brugia malayi larval opioid receptor 0.0148 0.1118 0.188
Plasmodium vivax SET domain protein, putative 0.0029 0.0098 0.0153
Loa Loa (eye worm) hypothetical protein 0.0069 0.0439 0.0738
Onchocerca volvulus 0.0148 0.1118 0.1854
Loa Loa (eye worm) hypothetical protein 0.002 0.0019 0.0032
Schistosoma mansoni biogenic amine receptor 0.0148 0.1118 0.1299
Loa Loa (eye worm) mbt repeat family protein 0.0046 0.0248 0.0417
Toxoplasma gondii histone deacetylase HDAC5 0.0118 0.0863 0.1685
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0046 0.0241 0.028
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.002 0.0019 0.0019
Echinococcus granulosus rhodopsin orphan GPCR 0.0148 0.1118 0.1118
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0024 0.0056 0.0281
Trichomonas vaginalis type I geranylgeranyltransferase beta subunit, putative 0.0037 0.0163 0.0814
Brugia malayi hypothetical protein 0.007 0.0448 0.0753
Giardia lamblia Beta tubulin 0.0049 0.0272 0.1356
Trypanosoma brucei lanosterol synthase 0.004 0.0194 0.0966
Schistosoma mansoni gabp alpha 0.0145 0.1094 0.1272
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.002 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0148 0.1118 0.188
Onchocerca volvulus Phospholipase A2 homolog 0.0709 0.5946 1
Echinococcus granulosus histone deacetylase 7 0.0186 0.1452 0.1452
Toxoplasma gondii beta-tubulin, putative 0.0049 0.0272 0.0531
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0027 0.0079 0.0092
Echinococcus granulosus polycomb protein SCMH1 0.0046 0.0248 0.0248
Leishmania major beta tubulin 0.0049 0.0272 0.1356
Echinococcus multilocularis polycomb protein SCMH1 0.0046 0.0248 0.0248
Loa Loa (eye worm) hypothetical protein 0.002 0.0019 0.0032
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0021 0.0105
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0021 0.003 0.005
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0027 0.0079 0.0092
Echinococcus multilocularis mothers against decapentaplegic 5 0.0018 0.0004 0.0004
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0064 0.0317
Onchocerca volvulus 0.0041 0.0201 0.0307
Brugia malayi ImpB/MucB/SamB family protein 0.002 0.0021 0.0035
Echinococcus multilocularis tubulin beta 1 chain 0.0049 0.0272 0.0272
Schistosoma mansoni ets-related 0.044 0.3629 0.4218
Schistosoma mansoni neuropeptide f receptor 76f 0.0148 0.1118 0.1299
Giardia lamblia Prenyltransferase 0.0037 0.0163 0.0814
Echinococcus multilocularis zinc finger protein 0.0019 0.0013 0.0013
Loa Loa (eye worm) neuropeptide F receptor 0.0148 0.1118 0.188
Echinococcus multilocularis rhodopsin orphan GPCR 0.0148 0.1118 0.1118
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0148 0.1118 0.1118
Loa Loa (eye worm) hypothetical protein 0.0148 0.1118 0.188
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0024 0.0056 0.0065
Brugia malayi hypothetical protein 0.0041 0.0201 0.0338
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0148 0.1118 0.1118
Trypanosoma cruzi protein farnesyltransferase, putative 0.0037 0.0163 0.0814
Echinococcus granulosus rhodopsin orphan GPCR 0.0148 0.1118 0.1118
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0041 0.0201 0.0234
Onchocerca volvulus 0.0039 0.0189 0.0286
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0027 0.0079 0.0133
Schistosoma mansoni hypothetical protein 0.0021 0.003 0.0035
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0148 0.1118 0.1118
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0148 0.1118 0.188
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.002 0.0019 0.0019
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0027 0.0079 0.0079
Loa Loa (eye worm) neuropeptide F receptor 0.0148 0.1118 0.188
Brugia malayi AKH receptor 0.0148 0.1118 0.188
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0027 0.0079 0.0133
Plasmodium vivax histone deacetylase, putative 0.0186 0.1452 0.6158
Schistosoma mansoni ets-related 0.0021 0.003 0.0035
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0148 0.1118 0.1299
Onchocerca volvulus 0.0039 0.0189 0.0286
Echinococcus granulosus neuropeptide Y receptor 0.0148 0.1118 0.1118
Loa Loa (eye worm) norepinephrine transporter 0.0157 0.1203 0.2023
Mycobacterium tuberculosis Halimadienyl diphosphate synthase 0.004 0.0194 1
Echinococcus granulosus orexin receptor type 2 0.0148 0.1118 0.1118
Loa Loa (eye worm) fli-1 protein 0.044 0.3629 0.6104
Onchocerca volvulus 0.0148 0.1118 0.1854
Echinococcus granulosus ETS domain containing protein Elk 1 0.0021 0.003 0.003
Plasmodium vivax histone deacetylase 2, putative 0.0186 0.1452 0.6158
Schistosoma mansoni retinoid-x-receptor (RXR) 0.002 0.0019 0.0022
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0148 0.1118 0.1299
Brugia malayi Melatonin receptor type 1A 0.0148 0.1118 0.188
Trypanosoma cruzi histone deacetylase, putative 0.0186 0.1452 0.7242
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0019 0.0019
Trypanosoma brucei histone deacetylase 1 0.0251 0.2006 1
Trypanosoma cruzi histone deacetylase, putative 0.0186 0.1452 0.7242
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0021 0.0105
Entamoeba histolytica hypothetical protein 0.0024 0.0056 0.0281
Leishmania major histone deacetylase, putative 0.0186 0.1452 0.7242
Plasmodium vivax histone deacetylase 1, putative 0.0251 0.2006 0.8611
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0024 0.0056 0.0281
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0148 0.1118 0.188
Echinococcus granulosus neuropeptide receptor A26 0.0148 0.1118 0.1118
Brugia malayi hypothetical protein 0.0148 0.1118 0.188
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0148 0.1118 0.1299
Echinococcus multilocularis rhodopsin orphan GPCR 0.0148 0.1118 0.1118
Echinococcus granulosus ETS transcription factor Elf 2 0.0021 0.003 0.003
Loa Loa (eye worm) TYRA-2 protein 0.0148 0.1118 0.188
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0148 0.1118 0.1299
Echinococcus granulosus smad 0.0018 0.0004 0.0004
Schistosoma mansoni hypothetical protein 0.0148 0.1118 0.1299
Schistosoma mansoni myelin transcription factor 1 myt1 0.0053 0.0303 0.0352
Leishmania major histone deacetylase, putative 0.0186 0.1452 0.7242
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0148 0.1118 0.1299
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0027 0.0079 0.0079

Activities

Activity type Activity value Assay description Source Reference
MIC (functional) > 31.2 ug ml-1 Antimicrobial activity against Escherichia coli ATCC 25922 after 17 to 20 hrs by serial dilution method ChEMBL. 24946217
MIC (functional) > 62.5 ug ml-1 Antimicrobial activity against Candida albicans ATCC 14053 after 17 to 20 hrs by serial dilution method ChEMBL. 24946217

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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