Detailed information for compound 205689

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 417.249 | Formula: C18H14Cl2N6O2--
  • H donors: 1 H acceptors: 5 LogP: 4.87 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: [O-][N+](=O)c1ccc2c(c1)c(NCc1ccccc1)nc(n2)n1cncc1.[Cl-].[Cl-]
  • InChi: 1S/C18H14N6O2.2ClH/c25-24(26)14-6-7-16-15(10-14)17(20-11-13-4-2-1-3-5-13)22-18(21-16)23-9-8-19-12-23;;/h1-10,12H,11H2,(H,20,21,22);2*1H/p-2
  • InChiKey: UABBYQLNJKEERR-UHFFFAOYSA-L  


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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis calcium dependent protein kinase 0.0134 0.0133 0.0161
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0307 0.1045 0.1292
Onchocerca volvulus 0.0258 0.0785 0.1796
Echinococcus granulosus Immunoglobulin 0.0153 0.0235 0.0213
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0456 0.1832 0.2214
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0289 0.0952 0.0932
Loa Loa (eye worm) TK/FER protein kinase 0.0202 0.0489 0.0515
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0468 0.1892 0.2286
Loa Loa (eye worm) hypothetical protein 0.0365 0.1348 0.1445
Trichomonas vaginalis AGC family protein kinase 0.0127 0.0095 0.0362
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0153 0.0235 0.0455
Onchocerca volvulus 0.0126 0.0093 0.0165
Echinococcus multilocularis mitogen activated protein kinase 0.0169 0.0318 0.0384
Schistosoma mansoni atypical protein kinase C 0.0594 0.2555 0.4952
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.043 0.1694 0.2047
Schistosoma mansoni serine/threonine protein kinase 0.018 0.0377 0.073
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0147 0.0202 0.0204
Trypanosoma brucei aurora B kinase 0.0291 0.096 0.1153
Schistosoma mansoni growth factor receptor-bound protein 0.0198 0.0471 0.0913
Echinococcus multilocularis insulin receptor 0.0439 0.1742 0.2105
Schistosoma mansoni serine/threonine protein kinase 0.0112 0.0015 0.0029
Echinococcus multilocularis cGMP dependent protein kinase 1 0.027 0.0847 0.1024
Echinococcus multilocularis lipoxygenase domain containing protein 0.0131 0.0116 0.0141
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0113 0.0022 0.0009
Echinococcus multilocularis STE20 serine:threonine protein kinase 0.098 0.459 0.5548
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0153 0.0235 0.0284
Giardia lamblia Kinase, STE STE20 0.0174 0.0341 0.0155
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0468 0.1892 0.1873
Loa Loa (eye worm) AGC/NDR protein kinase 0.0335 0.1194 0.1278
Brugia malayi SH2 domain containing protein 0.0113 0.0022 0.0009
Schistosoma mansoni protein kinase 0.0157 0.0256 0.0496
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0238 0.0683 0.0698
Schistosoma mansoni protein kinase 0.0131 0.0116 0.0225
Trichomonas vaginalis CK1 family protein kinase 0.0218 0.0577 0.2236
Schistosoma mansoni ste20-related kinase 0.0409 0.1581 0.3064
Schistosoma mansoni serine/threonine protein kinase 0.0227 0.0622 0.1207
Entamoeba histolytica hypothetical protein 0.075 0.3381 1
Brugia malayi SH2 domain containing protein 0.0113 0.0022 0.0009
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0456 0.1832 0.2214
Loa Loa (eye worm) hypothetical protein 0.0147 0.0202 0.0204
Entamoeba histolytica protein kinase, putative 0.0597 0.2573 0.7596
Echinococcus granulosus serine:threonine protein kinase TAO1 0.0442 0.1758 0.174
Echinococcus granulosus tyrosine kinase 0.0375 0.1404 0.1385
Echinococcus multilocularis RUN 0.0119 0.0054 0.0065
Echinococcus multilocularis phosphatidylinositol 3 kinase regulatory subunit 0.0113 0.0022 0.0027
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0133 0.0129 0.0124
Echinococcus multilocularis 0.0126 0.0088 0.0107
Echinococcus granulosus defective proboscis extension response 0.0153 0.0235 0.0213
Loa Loa (eye worm) TK/FER protein kinase 0.0202 0.0489 0.0515
Trichomonas vaginalis AGC family protein kinase 0.0165 0.0294 0.1136
Trichomonas vaginalis AGC family protein kinase 0.0127 0.0095 0.0362
Loa Loa (eye worm) AGC/PKA protein kinase 0.0227 0.0622 0.0659
Entamoeba histolytica protein kinase, putative 0.0278 0.0892 0.2591
Echinococcus granulosus mitogen activated protein kinase 0.0169 0.0318 0.0296
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0331 0.1169 0.1818
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0456 0.1832 0.2214
Schistosoma mansoni tyrosine kinase 0.0623 0.271 0.5254
Schistosoma mansoni protein kinase 0.0728 0.3262 0.6324
Echinococcus granulosus raf serine:threonine protein kinase 0.0171 0.0328 0.0306
Trichomonas vaginalis CMGC family protein kinase 0.0181 0.038 0.1471
Echinococcus granulosus tyrosine protein kinase ABL1 0.0611 0.2647 0.263
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.0658 0.2892 0.3117
Leishmania major protein kinase A catalytic subunit isoform 2 0.0227 0.0622 0.06
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0174 0.0341 0.032
Loa Loa (eye worm) AUR protein kinase 0.0291 0.096 0.1025
Trichomonas vaginalis CAMK family protein kinase 0.018 0.0377 0.1456
Echinococcus granulosus serine:threonine kinase SAD 1 0.018 0.0377 0.0355
Trichomonas vaginalis CMGC family protein kinase 0.0181 0.038 0.1471
Schistosoma mansoni serine/threonine protein kinase 0.0171 0.0328 0.0636
Echinococcus multilocularis casein kinase I delta 0.0218 0.0577 0.0698
Loa Loa (eye worm) doublecortin family protein 0.0119 0.0054 0.0044
Schistosoma mansoni serine/threonine protein kinase 0.0468 0.1892 0.3667
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0525 0.2196 0.2364
Echinococcus granulosus dual specificity 0.0278 0.0892 0.0872
Schistosoma mansoni signal transduction protein lnk-related 0.0113 0.0022 0.0044
Trichomonas vaginalis AGC family protein kinase 0.0291 0.096 0.3726
Trichomonas vaginalis CMGC family protein kinase 0.0258 0.0785 0.3045
Onchocerca volvulus 0.0119 0.0054 0.0074
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0245 0.0718 0.1108
Entamoeba histolytica hypothetical protein 0.0245 0.0718 0.2072
Loa Loa (eye worm) hypothetical protein 0.0712 0.3179 0.3428
Brugia malayi MAP kinase sur-1 0.0169 0.0318 0.0329
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.0442 0.1758 0.189
Entamoeba histolytica protein kinase, putative 0.0168 0.0311 0.086
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0174 0.0341 0.0413
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0501 0.2069 0.2051
Echinococcus multilocularis tyrosine protein kinase shark 0.0623 0.271 0.3276
Schistosoma mansoni SH2A 0.0113 0.0022 0.0044
Schistosoma mansoni tyrosine kinase 0.048 0.1956 0.3791
Trichomonas vaginalis AGC family protein kinase 0.0597 0.2573 1
Schistosoma mansoni lipoxygenase 0.0712 0.318 0.6164
Brugia malayi map kinase activated protein kinase protein 2 0.0782 0.3548 0.3828
Schistosoma mansoni serine/threonine protein kinase 0.0442 0.1758 0.3408
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.0889 0.4113 0.444
Onchocerca volvulus 0.0365 0.1348 0.3121
Echinococcus multilocularis calcium:calmodulin dependent protein kinase I 0.0144 0.0183 0.0222
Loa Loa (eye worm) hypothetical protein 0.0274 0.087 0.0928
Echinococcus granulosus mitogen activated protein kinase 14 0.1316 0.6363 0.6355
Echinococcus granulosus Glutaredoxin protein 5 0.0244 0.0713 0.0692
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0278 0.0892 0.1382
Brugia malayi casein kinase 1, delta 0.0218 0.0577 0.061
Brugia malayi SH2 domain containing protein 0.0113 0.0022 0.0009
Echinococcus granulosus tyrosine protein kinase shark 0.0623 0.271 0.2694
Echinococcus multilocularis SHC transforming protein 3 0.0113 0.0022 0.0027
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0244 0.0713 0.0862
Trichomonas vaginalis CMGC family protein kinase 0.0201 0.0488 0.189
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0203 0.0496 0.0392
Trichomonas vaginalis CAMK family protein kinase 0.0537 0.2258 0.8775
Entamoeba histolytica protein kinase, putative 0.0245 0.0718 0.2072
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0227 0.0622 0.0752
Trichomonas vaginalis CMGC family protein kinase 0.0201 0.0488 0.189
Loa Loa (eye worm) CAMK/PIM protein kinase 0.07 0.3115 0.3359
Echinococcus multilocularis phosphorylase kinase gamma subunit 0.0328 0.1154 0.1395
Leishmania major casein kinase, putative 0.0218 0.0577 0.0526
Schistosoma mansoni serine/threonine kinase 0.0335 0.1194 0.2314
Echinococcus multilocularis casein kinase I gamma 0.0425 0.1665 0.2013
Onchocerca volvulus 0.0646 0.2829 0.661
Schistosoma mansoni nck2/grb4 0.0194 0.045 0.0872
Loa Loa (eye worm) TK/EGFR protein kinase 0.0499 0.2057 0.2213
Brugia malayi Doublecortin family protein 0.0131 0.0116 0.0111
Echinococcus multilocularis cyclin dependent kinase 5 0.0238 0.0683 0.0825
Trypanosoma cruzi casein kinase, putative 0.0218 0.0577 0.0885
Echinococcus granulosus casein kinase i 0.0218 0.0577 0.0556
Entamoeba histolytica protein kinase, putative 0.0335 0.1194 0.3488
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0157 0.0256 0.038
Brugia malayi Serine/threonine-protein kinase SULU 0.0442 0.1758 0.189
Trichomonas vaginalis CMGC family protein kinase 0.0278 0.0892 0.3462
Brugia malayi SRC-1 0.0456 0.1832 0.1969
Loa Loa (eye worm) CAMK protein kinase 0.014 0.0163 0.0162
Trichomonas vaginalis AGC family protein kinase 0.0165 0.0294 0.1136
Onchocerca volvulus 0.0131 0.0116 0.0221
Loa Loa (eye worm) AGC/PKN protein kinase 0.0591 0.2543 0.2739
Schistosoma mansoni serine/threonine protein kinase 0.027 0.0849 0.1647
Trichomonas vaginalis AGC family protein kinase 0.0127 0.0095 0.0362
Brugia malayi Egg laying defective protein 4 0.027 0.0847 0.0902
Giardia lamblia Kinase, AGC AKT 0.0235 0.0665 0.1815
Trichomonas vaginalis CAMK family protein kinase 0.0231 0.0644 0.2496
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0307 0.1045 0.1622
Entamoeba histolytica protein kinase domain containing protein 0.0157 0.0256 0.0695
Brugia malayi RhoGAP domain containing protein 0.0196 0.0458 0.0481
Echinococcus granulosus Vam6:Vps39 protein 0.0221 0.0589 0.0568
Echinococcus multilocularis fibroblast growth factor receptor 4 0.048 0.1956 0.2364
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0227 0.0622 0.0601
Schistosoma mansoni serine/threonine protein kinase 0.0144 0.0184 0.0356
Loa Loa (eye worm) hypothetical protein 0.0113 0.0022 0.0009
Echinococcus granulosus serine:threonine protein kinase MARK2 0.043 0.1694 0.1675
Loa Loa (eye worm) hypothetical protein 0.0411 0.1592 0.171
Loa Loa (eye worm) TK/FAK protein kinase 0.11 0.5221 0.5641
Echinococcus granulosus nervana 2 0.0244 0.0713 0.0692
Echinococcus multilocularis cyclin dependent kinase 1 0.0238 0.0683 0.0825
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.0728 0.3262 0.3518
Schistosoma mansoni serine/threonine protein kinase 0.0238 0.0683 0.1323
Trichomonas vaginalis CAMK family protein kinase 0.0537 0.2258 0.8775
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0371 0.138 0.1479
Trichomonas vaginalis AGC family protein kinase 0.0127 0.0095 0.0362
Brugia malayi STAT protein, DNA binding domain containing protein 0.0113 0.0022 0.0009
Brugia malayi Homeodomain interacting protein kinase protein 1 0.0404 0.1555 0.1669
Giardia lamblia Kinase, CMGC GSK 0.0258 0.0785 0.2435
Brugia malayi Temporarily assigned gene name protein 59 0.0221 0.0589 0.0623
Plasmodium falciparum protein kinase, putative 0.0157 0.0256 0.1976
Echinococcus granulosus twitchin 0.0262 0.0808 0.0787
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0227 0.0622 0.0752
Trypanosoma brucei Casein kinase II 0.0201 0.0488 0.038
Giardia lamblia Kinase, CAMK CAMKL 0.018 0.0377 0.0337
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.0221 0.0589 0.0712
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.0782 0.3548 0.4288
Echinococcus multilocularis growth factor receptor bound protein 2 0.0194 0.045 0.0544
Schistosoma mansoni serine/threonine protein kinase 0.027 0.0849 0.1647
Loa Loa (eye worm) hypothetical protein 0.0221 0.0589 0.0623
Schistosoma mansoni serine/threonine protein kinase 0.018 0.0377 0.073
Loa Loa (eye worm) hypothetical protein 0.0282 0.0913 0.0973
Brugia malayi SH2 domain containing protein 0.0113 0.0022 0.0009
Brugia malayi Protein kinase domain containing protein 0.0597 0.2573 0.2772
Brugia malayi hypothetical protein 0.0184 0.0398 0.0416
Schistosoma mansoni serine/threonine protein kinase 0.0945 0.4409 0.8546
Trichomonas vaginalis STE family protein kinase 0.0174 0.0341 0.1319
Echinococcus multilocularis tyrosine kinase 0.0202 0.0489 0.0591
Loa Loa (eye worm) CAMK/PIM protein kinase 0.07 0.3115 0.3359
Loa Loa (eye worm) hypothetical protein 0.0169 0.032 0.0331
Onchocerca volvulus 0.0282 0.0913 0.2096
Loa Loa (eye worm) TK/ROR protein kinase 0.0128 0.0104 0.0097
Loa Loa (eye worm) protein kinase domain-containing protein 0.0425 0.1665 0.1789
Trichomonas vaginalis AGC family protein kinase 0.0127 0.0095 0.0362
Echinococcus multilocularis tyrosine protein kinase HCK 0.0262 0.0808 0.0977
Brugia malayi hypothetical protein 0.0202 0.0489 0.0515
Loa Loa (eye worm) TK/KIN16 protein kinase 0.1065 0.5037 0.5441
Trichomonas vaginalis CAMK family protein kinase 0.018 0.0377 0.1456
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0194 0.045 0.0872
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0501 0.2069 0.2501
Entamoeba histolytica serine/threonine protein kinase, putative 0.018 0.0377 0.1055
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0165 0.0294 0.0356
Entamoeba histolytica protein kinase, putative 0.0144 0.0184 0.048
Trichomonas vaginalis CAMK family protein kinase 0.0253 0.0761 0.2953
Loa Loa (eye worm) AGC/PKG protein kinase 0.027 0.0847 0.0902
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0501 0.2069 0.2226
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0194 0.045 0.0472
Trypanosoma cruzi cdc2-related kinase 3 0.0238 0.0683 0.1051
Brugia malayi Protein kinase domain containing protein 0.0376 0.1406 0.1508
Echinococcus multilocularis cyclin dependent kinase 1 0.0238 0.0683 0.0825
Schistosoma mansoni protein kinase 0.086 0.3961 0.7678
Brugia malayi intracellular kinase 0.0258 0.0785 0.0836
Schistosoma mansoni growth factor receptor-bound protein 0.0194 0.045 0.0872
Plasmodium falciparum NIMA related kinase 1 0.0273 0.0863 0.7915
Loa Loa (eye worm) CMGC/DYRK/HIPK protein kinase 0.0404 0.1555 0.1669
Loa Loa (eye worm) hypothetical protein 0.0154 0.0238 0.0243
Echinococcus granulosus protein tyrosine kinase 0.1088 0.5159 0.5148
Plasmodium falciparum cGMP-dependent protein kinase 0.027 0.0847 0.7757
Brugia malayi Variant SH3 domain containing protein 0.0194 0.045 0.0472
Echinococcus multilocularis mitogen activated protein kinase 11 0.1316 0.6363 0.7692
Trypanosoma cruzi polo-like protein kinase, putative 0.0537 0.2258 0.3534
Schistosoma mansoni tyrosine kinase 0.0439 0.1742 0.3376
Trichomonas vaginalis mitogen-activated protein kinase kinase kinase 3, MAPKKK3, MEKK3, putative 0.0112 0.0015 0.005
Entamoeba histolytica PH domain containing protein kinase, putative 0.0331 0.1169 0.3414
Entamoeba histolytica protein kinase, putative 0.0131 0.0116 0.0278
Echinococcus multilocularis expressed protein 0.0404 0.1554 0.1879
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0537 0.2258 0.2431
Entamoeba histolytica PH domain containing protein kinase, putative 0.0331 0.1169 0.3414
Trichomonas vaginalis CAMK family protein kinase 0.018 0.0377 0.1456
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0283 0.0917 0.1777
Schistosoma mansoni serine/threonine protein kinase 0.0335 0.1194 0.2314
Echinococcus multilocularis aurora kinase A 0.0291 0.096 0.1161
Echinococcus granulosus ephrin type A receptor 4 A 0.0215 0.0559 0.0538
Loa Loa (eye worm) hypothetical protein 0.0113 0.0022 0.0009
Loa Loa (eye worm) hypothetical protein 0.018 0.0377 0.0393
Loa Loa (eye worm) hypothetical protein 0.0282 0.0913 0.0973
Echinococcus granulosus aurora kinase A 0.0291 0.096 0.094
Brugia malayi SH2 domain containing protein 0.0202 0.0489 0.0515
Loa Loa (eye worm) TK/ABL protein kinase 0.0611 0.2647 0.2852
Echinococcus multilocularis serine:threonine kinase SAD 1 0.018 0.0377 0.0455
Onchocerca volvulus 0.0202 0.0489 0.1099
Trichomonas vaginalis CMGC family protein kinase 0.0238 0.0683 0.2646
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.0278 0.0892 0.0952
Echinococcus granulosus expressed protein 0.0168 0.0311 0.0289
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0456 0.1832 0.2214
Entamoeba histolytica protein kinase, putative 0.0165 0.0294 0.0809
Loa Loa (eye worm) hypothetical protein 0.0186 0.0405 0.0424
Giardia lamblia Aurora kinase 0.0291 0.096 0.3333
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0227 0.0622 0.0957
Loa Loa (eye worm) TK/FER protein kinase 0.0202 0.0489 0.0515
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0218 0.0577 0.061
Loa Loa (eye worm) hypothetical protein 0.0113 0.0022 0.0009
Echinococcus multilocularis Immunoglobulin 0.0153 0.0235 0.0284
Loa Loa (eye worm) SH2 domain-containing protein 0.0113 0.0022 0.0009
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0149 0.0214 0.0313
Entamoeba histolytica casein kinase, putative 0.0201 0.0488 0.1387
Echinococcus granulosus neuroglian 0.0193 0.0445 0.0424
Brugia malayi Protein kinase domain containing protein 0.0556 0.2354 0.2535
Trichomonas vaginalis AGC family protein kinase 0.0127 0.0095 0.0362
Loa Loa (eye worm) hypothetical protein 0.0113 0.0022 0.0009
Echinococcus multilocularis mitogen activated protein kinase 14 0.1316 0.6363 0.7692
Trichomonas vaginalis CMGC family protein kinase 0.0201 0.0488 0.189
Echinococcus multilocularis rho associated protein kinase 0.0646 0.2829 0.342
Entamoeba histolytica protein kinase, putative 0.0144 0.0184 0.048
Brugia malayi cytokine inducible SH2-containing protein 5 0.0113 0.0022 0.0009
Trichomonas vaginalis AGC family protein kinase 0.0291 0.096 0.3726
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.047 0.1905 0.2302
Echinococcus granulosus lipoxygenase domain containing protein 0.0119 0.0054 0.0032
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0456 0.1832 0.2214
Giardia lamblia Kinase, CMGC DYRK 0.0278 0.0892 0.2985
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.07 0.3115 0.3765
Echinococcus granulosus dual specificity 0.0278 0.0892 0.0872
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0456 0.1832 0.2214
Entamoeba histolytica protein kinase, putative 0.0291 0.096 0.2792
Echinococcus multilocularis protein kinase c iota type 0.0582 0.2491 0.3012
Onchocerca volvulus Serine\/threonine kinase homolog 0.0328 0.1154 0.2664
Brugia malayi SH2 domain containing protein 0.0801 0.3645 0.3934
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0537 0.2258 0.273
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0245 0.0718 0.0757
Giardia lamblia Kinase, CAMK CAMKL 0.018 0.0377 0.0337
Trichomonas vaginalis AGC family protein kinase 0.0127 0.0095 0.0362
Trypanosoma brucei cdc2-related kinase 1 0.0238 0.0683 0.0698
Schistosoma mansoni rab6-interacting 0.0119 0.0054 0.0105
Echinococcus granulosus tyrosine protein kinase Fyn 0.0456 0.1832 0.1813
Plasmodium vivax tyrosine kinase-like protein, putative 0.0164 0.0289 0.2333
Onchocerca volvulus 0.0149 0.0214 0.0451
Echinococcus granulosus homeodomain interacting protein kinase 3 0.0404 0.1555 0.1536
Echinococcus multilocularis nervana 2 0.0244 0.0713 0.0862
Echinococcus granulosus c src tyrosine kinase 0.0283 0.0917 0.0896
Brugia malayi Hr1 repeat family protein 0.0591 0.2543 0.2739
Echinococcus multilocularis Glutaredoxin protein 5 0.0244 0.0713 0.0862
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0313 0.1076 0.1301
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0153 0.0235 0.0455
Trichomonas vaginalis AGC family protein kinase 0.0597 0.2573 1
Schistosoma mansoni tyrosine kinase 0.0499 0.2057 0.3987
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.015 0.0215 0.0218
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0433 0.1711 0.1838
Brugia malayi Protein kinase domain containing protein 0.0384 0.1453 0.1558
Echinococcus granulosus serine:threonine protein kinase Chk2 0.0144 0.0184 0.0162
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0203 0.0496 0.0474
Entamoeba histolytica protein kinase domain containing protein 0.0278 0.0892 0.2591
Loa Loa (eye worm) TK/INSR protein kinase 0.0439 0.1742 0.1872
Schistosoma mansoni serine/threonine protein kinase 0.0537 0.2258 0.4378
Trichomonas vaginalis CAMK family protein kinase 0.0537 0.2258 0.8775
Schistosoma mansoni serine/threonine protein kinase 0.0203 0.0496 0.0961
Entamoeba histolytica protein kinase domain containing protein 0.0258 0.0785 0.2271
Echinococcus multilocularis mitogen activated protein kinase 11 0.1316 0.6363 0.7692
Loa Loa (eye worm) hypothetical protein 0.0911 0.4227 0.4563
Echinococcus granulosus protein kinase c iota type 0.0582 0.2491 0.2474
Trichomonas vaginalis CAMK family protein kinase 0.018 0.0377 0.1456
Schistosoma mansoni serine/threonine protein kinase 0.014 0.0163 0.0316
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0168 0.0311 0.009
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.029 0.0953 0.1152
Brugia malayi Fibronectin type III domain containing protein 0.0184 0.0398 0.0416
Brugia malayi Fes/CIP4 homology domain containing protein 0.0231 0.0644 0.0682
Echinococcus multilocularis casein kinase ii subunit alpha 0.0201 0.0488 0.059
Echinococcus multilocularis dual specificity protein kinase clk2 0.0307 0.1045 0.1263
Giardia lamblia Kinase, CMGC CDK 0.0238 0.0683 0.1907
Loa Loa (eye worm) hypothetical protein 0.0382 0.1441 0.1546
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0375 0.1404 0.1385
Schistosoma mansoni tyrosine kinase 0.015 0.0219 0.0425
Echinococcus granulosus dual specificity protein kinase clk2 0.0307 0.1045 0.1025
Schistosoma mansoni serine/threonine protein kinase 0.0335 0.1194 0.2314
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.07 0.3115 0.3099
Loa Loa (eye worm) hypothetical protein 0.0176 0.0355 0.037
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.04 0.1535 0.1855
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0203 0.0496 0.0599
Trichomonas vaginalis AGC family protein kinase 0.0127 0.0095 0.0362
Schistosoma mansoni shc transforming protein 0.0113 0.0022 0.0044
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0712 0.318 0.3844
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0801 0.3645 0.3631
Plasmodium falciparum calcium-dependent protein kinase 4 0.0203 0.0496 0.4322
Trichomonas vaginalis AGC family protein kinase 0.0597 0.2573 1
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.07 0.3115 0.7282
Echinococcus granulosus tyrosine protein kinase Lyn 0.0525 0.2195 0.2177
Schistosoma mansoni protein kinase 0.0218 0.0577 0.1119
Schistosoma mansoni serine/threonine protein kinase 0.0227 0.0622 0.1207
Plasmodium vivax calcium-dependent protein kinase, putative 0.0203 0.0496 0.4344
Entamoeba histolytica PH domain containing protein kinase, putative 0.0245 0.0715 0.2064
Echinococcus granulosus tyrosine protein kinase Srms 0.1006 0.4731 0.4719
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0113 0.0022 0.0027
Schistosoma mansoni serine/threonine protein kinase 0.0181 0.038 0.0738
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0158 0.026 0.0238
Schistosoma mansoni tyrosine kinase 0.0161 0.0274 0.0532
Schistosoma mansoni protein kinase C mu 0.0433 0.1711 0.3316
Trichomonas vaginalis AGC family protein kinase 0.0165 0.0294 0.1136
Brugia malayi C1-like domain containing protein 0.0433 0.1711 0.1838
Trichomonas vaginalis CMGC family protein kinase 0.0169 0.0318 0.1227
Brugia malayi Protein kinase domain containing protein 0.1863 0.9246 1
Plasmodium falciparum protein serine/threonine kinase-1 0.0307 0.1045 0.9696
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0227 0.0622 0.0957
Toxoplasma gondii casein kinase I 0.0218 0.0577 0.1443
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0169 0.0318 0.0477
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0203 0.0496 0.1078
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0172 0.0334 0.0347
Schistosoma mansoni tyrosine kinase 0.0283 0.0917 0.1777
Echinococcus granulosus protein kinase C gamma type 0.0416 0.1619 0.1601
Brugia malayi probable protein kinase 0.0527 0.2202 0.2371
Loa Loa (eye worm) TK/FER protein kinase 0.0202 0.0489 0.0515
Schistosoma mansoni serine/threonine protein kinase 0.04 0.1535 0.2976
Trichomonas vaginalis CMGC family protein kinase 0.0238 0.0683 0.2646
Schistosoma mansoni tyrosine kinase 0.051 0.2114 0.4099
Trichomonas vaginalis CMGC family protein kinase 0.0258 0.0785 0.3045
Echinococcus granulosus activin receptor type 0.0157 0.0256 0.0234
Brugia malayi Protein kinase domain containing protein 0.0562 0.2388 0.2571
Schistosoma mansoni tyrosine kinase 0.0362 0.1335 0.2587
Brugia malayi Protein kinase domain containing protein 0.0425 0.1665 0.1789
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.018 0.0377 0.057
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0169 0.0318 0.0477
Echinococcus granulosus protein kinase shaggy 0.0258 0.0785 0.0764
Schistosoma mansoni protein kinase 0.086 0.3961 0.7678
Brugia malayi Kinase associated domain 1 family protein 0.0201 0.0487 0.0512
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0244 0.0713 0.0692
Schistosoma mansoni serine/threonine protein kinase 0.0165 0.0294 0.057
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0499 0.2055 0.2484
Loa Loa (eye worm) hypothetical protein 0.0113 0.0022 0.0009
Echinococcus granulosus hypothetical protein 0.0238 0.0682 0.0661
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0165 0.0294 0.0272
Echinococcus multilocularis cGMP dependent protein kinase 1 0.027 0.0847 0.1024
Brugia malayi Protein kinase domain containing protein 0.04 0.1535 0.1648
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0169 0.0318 0.0477
Schistosoma mansoni hypothetical protein 0.0119 0.0054 0.0105
Schistosoma mansoni serine/threonine protein kinase 0.0291 0.096 0.1861
Echinococcus multilocularis dual specificity 0.0245 0.0718 0.0868
Loa Loa (eye worm) hypothetical protein 0.0357 0.1306 0.1399
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0128 0.0104 0.0081
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.018 0.0377 0.0393
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.043 0.1694 0.2047
Loa Loa (eye worm) hypothetical protein 0.0473 0.1921 0.2066
Entamoeba histolytica protein kinase , putative 0.0291 0.096 0.2792
Loa Loa (eye worm) STAT protein 0.0113 0.0022 0.0009
Brugia malayi Protein kinase domain containing protein 0.0202 0.0489 0.0515
Loa Loa (eye worm) TK/EPH protein kinase 0.025 0.0742 0.0788
Brugia malayi Protein kinase domain containing protein 0.07 0.3115 0.3359
Loa Loa (eye worm) hypothetical protein 0.0227 0.0622 0.0659
Schistosoma mansoni tyrosine kinase 0.0362 0.1335 0.2587
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.0306 0.104 0.1111
Schistosoma mansoni serine/threonine protein kinase 0.0646 0.2829 0.5484
Onchocerca volvulus 0.0221 0.0589 0.1334
Echinococcus granulosus STE20 serine:threonine protein kinase 0.098 0.459 0.4578
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0238 0.0683 0.0724
Schistosoma mansoni serine/threonine protein kinase 0.0278 0.0892 0.173
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0221 0.0589 0.1142
Loa Loa (eye worm) hypothetical protein 0.0235 0.0664 0.0704
Giardia lamblia Kinase, NEK 0.0273 0.0863 0.2834
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0169 0.0318 0.0101
Entamoeba histolytica protein kinase 2, putative 0.0313 0.1076 0.3137
Entamoeba histolytica casein kinase, putative 0.0218 0.0577 0.1651
Plasmodium falciparum serine/threonine protein kinase KIN 0.018 0.0377 0.3157
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0307 0.1045 0.1622
Echinococcus granulosus casein kinase I gamma 0.0425 0.1665 0.1646
Schistosoma mansoni serine/threonine kinase 0.0432 0.1704 0.3303
Schistosoma mansoni serine/threonine protein kinase 0.0218 0.0577 0.1119
Brugia malayi P38 map kinase family protein 2 0.1316 0.6363 0.6877
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0278 0.0892 0.1042
Trichomonas vaginalis AGC family protein kinase 0.0227 0.0622 0.2412
Brugia malayi Furin-like cysteine rich region family protein 0.0499 0.2057 0.2213
Onchocerca volvulus 0.015 0.0217 0.0458
Echinococcus multilocularis 0.0238 0.0682 0.0825
Schistosoma mansoni serine/threonine protein kinase 0.0227 0.0622 0.1207
Brugia malayi Variant SH3 domain containing protein 0.0133 0.0129 0.0124
Echinococcus granulosus tyrosine protein kinase Fyn 0.0456 0.1832 0.1813
Leishmania major protein kinase A catalytic subunit 0.0227 0.0622 0.06
Trypanosoma cruzi casein kinase, putative 0.0218 0.0577 0.0885
Loa Loa (eye worm) hypothetical protein 0.1188 0.5689 0.6147
Entamoeba histolytica cell division protein kinase 2, putative 0.0238 0.0683 0.1966
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.048 0.1956 0.2364
Echinococcus granulosus serine:threonine protein kinase MARK2 0.043 0.1694 0.1675
Trichomonas vaginalis CAMK family protein kinase 0.018 0.0377 0.1456
Entamoeba histolytica serine/threonine protein kinase STE20, putative 0.0171 0.0327 0.0908
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0307 0.1044 0.405
Entamoeba histolytica protein kinase, putative 0.0205 0.0509 0.1448
Brugia malayi Variant SH3 domain containing protein 0.0196 0.0458 0.0481
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0165 0.0294 0.0304
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0258 0.0785 0.1522
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0238 0.0683 0.1918
Giardia lamblia Kinase, AGC PKA 0.0313 0.1076 0.3928
Leishmania major protein kinase A catalytic subunit isoform 1 0.0227 0.0622 0.06
Loa Loa (eye worm) hypothetical protein 0.0229 0.0634 0.0672
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0335 0.1194 0.1443
Echinococcus multilocularis serine:threonine protein kinase N2 0.0256 0.0775 0.0937
Entamoeba histolytica protein kinase domain containing protein 0.0258 0.0785 0.2271
Trypanosoma brucei STE20-like serine/threonine-protein kinase 1, putative 0.0171 0.0327 0.0117
Leishmania major protein kinase, putative 0.0203 0.0496 0.0392
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0196 0.0458 0.0887
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0171 0.0327 0.0492
Echinococcus multilocularis dual specificity 0.0278 0.0892 0.1079
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0258 0.0785 0.0764
Trichomonas vaginalis STE family protein kinase 0.0273 0.0863 0.3348
Brugia malayi Protein kinase domain containing protein 0.0307 0.1045 0.1117
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0201 0.0488 0.0514
Brugia malayi Protein kinase c protein 2 0.0232 0.065 0.0689
Brugia malayi serine/threonine kinase 12 0.0291 0.096 0.1025
Trichomonas vaginalis AGC family protein kinase 0.0597 0.2573 1
Schistosoma mansoni serine/threonine protein kinase 0.0507 0.21 0.407
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0537 0.2258 0.3279
Trichomonas vaginalis CK1 family protein kinase 0.0218 0.0577 0.2236
Trichomonas vaginalis AGC family protein kinase 0.0597 0.2573 1
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0313 0.1076 1
Brugia malayi Protein kinase domain containing protein 0.0238 0.0683 0.0724
Echinococcus granulosus serine:threonine protein kinase N2 0.0256 0.0775 0.0755
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0801 0.3645 0.4407
Loa Loa (eye worm) hypothetical protein 0.0458 0.184 0.1978
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0196 0.0458 0.0436
Entamoeba histolytica protein kinase, putative 0.0258 0.0785 0.2271
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0196 0.0458 0.0481
Toxoplasma gondii AGC kinase 0.0227 0.0622 0.1647
Loa Loa (eye worm) hypothetical protein 0.0202 0.0489 0.0515
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0227 0.0622 0.0957
Echinococcus multilocularis serine:threonine protein kinase Chk2 0.0144 0.0184 0.0222
Echinococcus granulosus Protein kinase C brain isozyme 0.0499 0.2055 0.2037
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0258 0.0785 0.0836
Schistosoma mansoni cell adhesion molecule 0.0217 0.0568 0.1102
Brugia malayi Tyrosine-protein kinase abl-1 0.0253 0.0759 0.0808
Schistosoma mansoni suppressor of cytokine signaling 0.0113 0.0022 0.0044
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.0432 0.1704 0.1831
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0221 0.0589 0.0904
Brugia malayi SH2 domain containing protein 0.0113 0.0022 0.0009
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0456 0.1832 0.1813
Echinococcus granulosus c-Jun N-terminal kinases 0.0525 0.2196 0.2178
Echinococcus multilocularis CDC7 cell division cycle 7 0.0181 0.038 0.046
Trypanosoma brucei protein kinase, putative 0.0169 0.0318 0.0101
Loa Loa (eye worm) hypothetical protein 0.0221 0.0589 0.0623
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.027 0.0847 0.2656
Trichomonas vaginalis 3-phosphoinositide dependent protein kinase-1, putative 0.0127 0.0095 0.0362
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0218 0.0577 0.061
Trichomonas vaginalis ribosomal protein S6 kinase, 90kD, polypeptide, putative 0.0127 0.0095 0.0362
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0335 0.1194 0.1174
Echinococcus multilocularis serine:threonine protein kinase N2 0.0591 0.2543 0.3074
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0291 0.0958 0.1158
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0128 0.0104 0.0125
Onchocerca volvulus 0.0181 0.038 0.0843
Schistosoma mansoni serine/threonine protein kinase 0.018 0.0377 0.073
Trichomonas vaginalis CAMK family protein kinase 0.018 0.0377 0.1456
Echinococcus multilocularis death associated protein kinase 1 0.1679 0.8273 1
Trichomonas vaginalis CMGC family protein kinase 0.0278 0.0892 0.3462
Onchocerca volvulus 0.0202 0.0489 0.1099
Trichomonas vaginalis CAMK family protein kinase 0.018 0.0377 0.1456
Giardia lamblia Kinase, CDC7 0.0181 0.038 0.0356
Echinococcus granulosus N chimaerin 0.0196 0.0458 0.0436
Entamoeba histolytica p21-activated kinase 0.0191 0.0434 0.1227
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0307 0.1045 0.3547
Trypanosoma cruzi SNF1-related protein kinases, putative 0.018 0.0377 0.057
Trichomonas vaginalis AGC family protein kinase 0.0273 0.0863 0.3348
Trypanosoma brucei rac serine-threonine kinase, putative 0.0597 0.2573 0.3795
Echinococcus multilocularis serine threonine protein kinase 0.0416 0.1619 0.1958
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0537 0.2258 0.2241
Trichomonas vaginalis CAMK family protein kinase 0.0229 0.0634 0.2456
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0809 0.3692 0.4463
Onchocerca volvulus 0.0577 0.2466 0.5755
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0157 0.0256 0.038
Echinococcus granulosus dual specificity 0.0278 0.0892 0.0872
Leishmania major protein kinase, putative 0.0291 0.096 0.1153
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0307 0.1045 0.1292
Schistosoma mansoni protein kinase 0.0174 0.0341 0.0662
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.018 0.0377 0.0198
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0258 0.0785 0.0949
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.0278 0.0892 0.1042
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0291 0.096 0.094
Loa Loa (eye worm) hypothetical protein 0.0153 0.0235 0.0239
Schistosoma mansoni tyrosine kinase 0.0274 0.0868 0.1683
Loa Loa (eye worm) SRC-1 0.0456 0.1832 0.1969
Schistosoma mansoni protein kinase 0.0384 0.1453 0.2816
Echinococcus multilocularis serine:threonine protein kinase 3 0.0511 0.2119 0.2561
Schistosoma mansoni serine/threonine protein kinase 0.0499 0.2055 0.3983
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0174 0.0341 0.032
Schistosoma mansoni serine/threonine protein kinase 0.0238 0.0683 0.1323
Loa Loa (eye worm) hypothetical protein 0.0142 0.0173 0.0173
Leishmania major casein kinase II, putative 0.0201 0.0488 0.038
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.0113 0.0022 0.0044
Onchocerca volvulus Serine\/threonine kinase homolog 0.0537 0.2258 0.5266
Trichomonas vaginalis CAMK family protein kinase 0.0537 0.2258 0.8775
Echinococcus multilocularis expressed conserved protein 0.027 0.0847 0.1024
Brugia malayi Protein kinase domain containing protein 0.0202 0.0489 0.0515
Plasmodium falciparum glycogen synthase kinase 3 0.0258 0.0785 0.7154
Trichomonas vaginalis CAMK family protein kinase 0.018 0.0377 0.1456
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0165 0.0294 0.0304
Echinococcus granulosus casein kinase I alpha 0.0218 0.0577 0.0556
Trichomonas vaginalis STE family protein kinase 0.0174 0.0341 0.1319
Echinococcus multilocularis raf serine:threonine protein kinase 0.0171 0.0328 0.0397
Brugia malayi ephrin receptor 1 precursor 0.0148 0.0207 0.0209
Echinococcus multilocularis neuroglian 0.0193 0.0445 0.0538
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0202 0.0489 0.1389
Echinococcus multilocularis casein kinase I alpha 0.0218 0.0577 0.0698
Toxoplasma gondii aurora kinase 0.0291 0.096 0.3166
Echinococcus granulosus cGMP dependent protein kinase 1 0.027 0.0847 0.0826
Echinococcus multilocularis suppressor of cytokine signaling 6 0.0113 0.0022 0.0027
Schistosoma mansoni loxhd1 0.0119 0.0054 0.0105
Brugia malayi Calcitonin receptor-like protein seb-1 0.0147 0.0202 0.0204
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.04 0.1535 0.1516
Loa Loa (eye worm) STE/STE20/SLK protein kinase 0.0384 0.1453 0.1558
Echinococcus multilocularis serine:threonine protein kinase 38 0.0335 0.1194 0.1443
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0203 0.0496 0.0599
Brugia malayi phosphoinositide-dependent protein kinase I 0.0165 0.0294 0.0304
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0245 0.0718 0.0763
Echinococcus granulosus dual specificity 0.0245 0.0718 0.0697
Giardia lamblia Kinase, NEK 0.0273 0.0863 0.2834
Loa Loa (eye worm) hypothetical protein 0.0126 0.0093 0.0085
Schistosoma mansoni serine/threonine protein kinase 0.0169 0.0318 0.0616
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0182 0.0385 0.1081
Schistosoma mansoni serine/threonine protein kinase 0.0501 0.2069 0.401
Entamoeba histolytica serine/threonine-protein kinase 3, putative 0.0171 0.0327 0.0908
Trypanosoma cruzi cdc2-related kinase 1 0.0238 0.0683 0.1051
Loa Loa (eye worm) AGC/PKA protein kinase 0.0227 0.0622 0.0659
Echinococcus multilocularis 0.0306 0.104 0.1257
Loa Loa (eye worm) CDC7 protein kinase 0.0181 0.038 0.0397
Entamoeba histolytica protein kinase, putative 0.0148 0.0209 0.0555
Schistosoma mansoni tyrosine kinase 0.0498 0.2051 0.3976
Brugia malayi Protein kinase domain containing protein 0.0202 0.0489 0.0515
Echinococcus granulosus tyrosine protein kinase HCK 0.0262 0.0808 0.0788
Trichomonas vaginalis AGC family protein kinase 0.0127 0.0095 0.0362
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0227 0.0622 0.1647
Schistosoma mansoni kinase 0.0574 0.245 0.475
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0809 0.3692 0.3678
Schistosoma mansoni rab6-interacting 0.0119 0.0054 0.0105
Brugia malayi Protein kinase domain containing protein 0.0245 0.0718 0.0763
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0169 0.0318 0.0101
Plasmodium falciparum protein kinase 5 0.0238 0.0683 0.615
Schistosoma mansoni serine/threonine protein kinase 0.0245 0.0718 0.1392
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.0229 0.0634 0.0672
Schistosoma mansoni tyrosine kinase 0.0732 0.3285 0.6368
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0203 0.0496 0.0522
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0169 0.0318 0.0477
Trichomonas vaginalis CMGC family protein kinase 0.0181 0.038 0.1471
Loa Loa (eye worm) TK protein kinase 0.0262 0.0808 0.086
Schistosoma mansoni serine/threonine protein kinase 0.07 0.3115 0.6037
Echinococcus granulosus protein kinase 0.0306 0.104 0.102
Schistosoma mansoni serine/threonine protein kinase 0.042 0.1642 0.3183
Echinococcus granulosus rho-associated protein kinase 1 0.0646 0.2829 0.2813
Trichomonas vaginalis CMGC family protein kinase 0.0278 0.0892 0.3462
Trypanosoma brucei polo-like protein kinase 0.0537 0.2258 0.3279
Echinococcus multilocularis maternal embryonic leucine zipper kinase 0.0231 0.0644 0.0778
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0362 0.1335 0.1315
Loa Loa (eye worm) hypothetical protein 0.0113 0.0022 0.0009
Brugia malayi Immunoglobulin I-set domain containing protein 0.014 0.0163 0.0162
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.086 0.3961 0.4788
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0238 0.0683 0.0662
Schistosoma mansoni hypothetical protein 0.0201 0.0487 0.0943
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0658 0.2892 0.3117
Echinococcus multilocularis titin 0.014 0.0163 0.0197
Brugia malayi Cam kinase protein 1 0.0203 0.0496 0.0522
Schistosoma mansoni protein kinase 0.0157 0.0256 0.0496
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0203 0.0496 0.0474
Schistosoma mansoni serine/threonine protein kinase 0.0112 0.0015 0.0029
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0525 0.2196 0.2654
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0456 0.1832 0.1813
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0113 0.0022 0.0027
Trypanosoma brucei protein kinase, putative 0.0258 0.0785 0.0867
Echinococcus multilocularis expressed protein 0.0168 0.0311 0.0376
Echinococcus multilocularis SH2 motif 0.0113 0.0022 0.0027
Echinococcus multilocularis signal transduction protein lnk realted 0.0113 0.0022 0.0027
Echinococcus multilocularis dual specificity 0.0278 0.0892 0.1079
Trypanosoma cruzi cdc2-related kinase 1 0.0238 0.0683 0.1051
Echinococcus granulosus cyclin dependent kinase 1 0.0238 0.0683 0.0662
Trichomonas vaginalis AGC family protein kinase 0.0291 0.096 0.3726
Giardia lamblia Kinase, CMGC MAPK 0.0169 0.0318 0.0034
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0227 0.0622 0.0659
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.0221 0.0589 0.0568
Schistosoma mansoni nephrin 0.0224 0.0608 0.1179
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0258 0.0785 0.0867
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0201 0.0488 0.427
Trichomonas vaginalis CAMK family protein kinase 0.0537 0.2258 0.8775
Trichomonas vaginalis AGC family protein kinase 0.0127 0.0095 0.0362
Schistosoma mansoni serine/threonine protein kinase 0.0371 0.138 0.2674
Loa Loa (eye worm) thyroid receptor interactor 0.0231 0.0644 0.0682
Echinococcus multilocularis tyrosine protein kinase Srms 0.0375 0.1404 0.1697
Echinococcus multilocularis N chimaerin 0.0196 0.0458 0.0553
Echinococcus granulosus epidermal growth factor receptor 0.0499 0.2057 0.2039
Entamoeba histolytica protein kinase, putative 0.0182 0.0385 0.1081
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.018 0.0377 0.0198
Schistosoma mansoni serine/threonine protein kinase 0.027 0.0849 0.1647
Trypanosoma brucei serine/arginine-rich protein specific kinase SRPK, putative 0.0168 0.0311 0.009
Mycobacterium ulcerans hypothetical protein 0.0201 0.0484 0.5
Brugia malayi Protein kinase domain containing protein 0.1188 0.5689 0.6147
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0291 0.096 0.2792
Giardia lamblia Kinase, PLK 0.0537 0.2258 1
Brugia malayi SH2 domain containing protein 0.0113 0.0022 0.0009
Schistosoma mansoni adapter molecule crk 0.0194 0.045 0.0872
Loa Loa (eye worm) hypothetical protein 0.0245 0.0718 0.0763
Trichomonas vaginalis CAMK family protein kinase 0.018 0.0377 0.1456
Brugia malayi Protein kinase domain containing protein 0.0386 0.1462 0.1569
Loa Loa (eye worm) hypothetical protein 0.0274 0.087 0.0928
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0253 0.0758 0.0821
Echinococcus granulosus serine:threonine protein kinase N2 0.0591 0.2543 0.2526
Echinococcus multilocularis tensin 0.0113 0.0022 0.0027
Echinococcus multilocularis mitogen activated protein kinase 14 0.1316 0.6363 0.7692
Entamoeba histolytica protein kinase, putative 0.0597 0.2573 0.7596
Brugia malayi Protein kinase domain containing protein 0.0439 0.1742 0.1872
Loa Loa (eye worm) hypothetical protein 0.0113 0.0022 0.0009
Schistosoma mansoni serine/threonine protein kinase 0.0782 0.3548 0.6877
Loa Loa (eye worm) hypothetical protein 0.0184 0.0398 0.0416
Schistosoma mansoni tensin 0.0113 0.0022 0.0044
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0203 0.0496 0.0522
Echinococcus granulosus cGMP dependent protein kinase 1 0.027 0.0847 0.0826
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0291 0.096 0.1161
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0174 0.0341 0.032
Loa Loa (eye worm) TK/FER protein kinase 0.0202 0.0489 0.0515
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0686 0.304 0.3278
Trichomonas vaginalis CAMK family protein kinase 0.018 0.0377 0.1456
Brugia malayi Protein kinase domain containing protein 0.0126 0.009 0.0083
Brugia malayi Protein kinase domain containing protein 0.0432 0.1704 0.1831
Echinococcus multilocularis NCK adaptor protein 0.0198 0.0471 0.0569
Schistosoma mansoni ephrin receptor 0.0215 0.0559 0.1084
Loa Loa (eye worm) TK protein kinase 0.0687 0.3049 0.3288
Loa Loa (eye worm) TK/FER protein kinase 0.0202 0.0489 0.0515
Echinococcus granulosus cyclin dependent kinase 5 0.0238 0.0683 0.0662
Onchocerca volvulus 0.0202 0.0489 0.1099
Brugia malayi Stress-activated protein kinase jnk-1 0.0525 0.2196 0.2364
Loa Loa (eye worm) CAMK/CAMKL/PASK protein kinase 0.0158 0.0259 0.0265
Brugia malayi Protein kinase domain containing protein 0.1188 0.5689 0.6147
Schistosoma mansoni serine/threonine protein kinase 0.043 0.1694 0.3283
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0196 0.0458 0.0887
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0327 0.115 0.1231
Echinococcus granulosus serine:threonine protein kinase 0.0229 0.0634 0.0613
Brugia malayi Protein kinase domain containing protein 0.0728 0.3262 0.3518
Trypanosoma cruzi serine/arginine-rich protein specific kinase SRPK, putative 0.0168 0.0311 0.0466
Entamoeba histolytica protein kinase, putative 0.0262 0.0808 0.234
Echinococcus granulosus casein kinase I alpha 0.0218 0.0577 0.0556
Brugia malayi Tyrosine-protein kinase abl-1 0.0439 0.1742 0.1871
Loa Loa (eye worm) hypothetical protein 0.0153 0.0235 0.0239
Trichomonas vaginalis AGC family protein kinase 0.0597 0.2573 1
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0728 0.3262 0.3943
Brugia malayi STE20-like kinase MST 0.0511 0.2119 0.228
Echinococcus granulosus nervana 2 0.0244 0.0713 0.0692
Trypanosoma brucei cdc2-related kinase 3 0.0238 0.0683 0.0698
Plasmodium falciparum casein kinase 2, alpha subunit 0.0201 0.0488 0.4247
Trypanosoma cruzi casein kinase II, putative 0.0201 0.0488 0.0745
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0227 0.0622 0.0752
Loa Loa (eye worm) cytokine inducible SH2-containing protein 5 0.0113 0.0022 0.0009
Loa Loa (eye worm) hypothetical protein 0.0176 0.0355 0.037
Brugia malayi Protein kinase domain 0.0174 0.0341 0.0355
Echinococcus granulosus mitogen activated protein kinase 11 0.1316 0.6363 0.6355
Trichomonas vaginalis CAMK family protein kinase 0.0253 0.0761 0.2953
Trypanosoma cruzi cdc2-related kinase 3 0.0238 0.0683 0.1051
Echinococcus granulosus tyrosine protein kinase Src42A 0.0291 0.0958 0.0938
Echinococcus granulosus protein kinase c epsilon type 0.042 0.1642 0.1623
Echinococcus multilocularis serine:threonine protein kinase N2 0.0335 0.1194 0.1443
Loa Loa (eye worm) AGC/AKT protein kinase 0.0597 0.2573 0.2772
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0113 0.0022 0.0027
Trichomonas vaginalis STE family protein kinase 0.0174 0.0341 0.1319
Entamoeba histolytica protein kinase domain containing protein 0.0291 0.096 0.2792
Plasmodium vivax serine/threonine kinase-1, putative 0.0307 0.1045 0.9697
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0245 0.0718 0.0757
Trichomonas vaginalis AGC family protein kinase 0.0127 0.0095 0.0362
Brugia malayi serine/threonine-protein kinase 6 0.0291 0.096 0.1025
Trichomonas vaginalis AGC family protein kinase 0.0127 0.0095 0.0362
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0203 0.0496 0.4344
Echinococcus granulosus lipoxygenase domain containing protein 0.0131 0.0116 0.0094
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0113 0.0022 0.0027
Echinococcus multilocularis tyrosine protein kinase Abl 0.0439 0.1742 0.2105
Loa Loa (eye worm) TK/ALK protein kinase 0.0555 0.2354 0.2534
Echinococcus granulosus tyrosine protein kinase Src64B 0.0456 0.1832 0.1813
Brugia malayi Protein kinase domain containing protein 0.0335 0.1194 0.1278
Brugia malayi Protein kinase domain containing protein 0.0168 0.0311 0.0322
Trichomonas vaginalis STE family protein kinase 0.0174 0.0341 0.1319
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0728 0.3262 0.3247
Echinococcus granulosus titin 0.014 0.0163 0.0141
Schistosoma mansoni tyrosine kinase 0.0274 0.0868 0.1683
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0203 0.0496 0.4344
Onchocerca volvulus Tyrosine kinase homolog 0.0919 0.4269 1
Schistosoma mansoni polycystin 1-related 0.0119 0.0054 0.0105
Loa Loa (eye worm) AUR protein kinase 0.0291 0.096 0.1025
Loa Loa (eye worm) hypothetical protein 0.0161 0.0274 0.0282
Trichomonas vaginalis STE family protein kinase 0.0171 0.0327 0.1264
Trichomonas vaginalis CMGC family protein kinase 0.0169 0.0318 0.1227
Echinococcus granulosus casein kinase I delta 0.0218 0.0577 0.0556
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0456 0.1832 0.2214
Plasmodium falciparum serine/threonine protein kinase 0.0168 0.0311 0.2516
Brugia malayi serine/threonine-protein kinase plk-2 0.0537 0.2258 0.2431
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.029 0.0953 0.0933
Trichomonas vaginalis CAMK family protein kinase 0.0203 0.0496 0.1919
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0169 0.0318 0.0101
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0456 0.1832 0.2214
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0174 0.0341 0.0413
Trichomonas vaginalis CAMK family protein kinase 0.0537 0.2258 0.8775
Echinococcus granulosus titin 0.014 0.0163 0.0141
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.018 0.0377 0.3184
Echinococcus multilocularis SH2 domain containing protein 7 0.0113 0.0022 0.0027
Loa Loa (eye worm) hypothetical protein 0.0609 0.2638 0.2842
Onchocerca volvulus 0.0218 0.0577 0.1306
Trichomonas vaginalis CAMK family protein kinase 0.018 0.0377 0.1456
Brugia malayi Protein kinase domain containing protein 0.0328 0.1154 0.1235
Brugia malayi casein kinase I 0.0218 0.0577 0.061
Schistosoma mansoni serine/threonine-protein kinase 0.0331 0.1169 0.2266
Echinococcus granulosus serine:threonine protein kinase mig 15 0.0458 0.184 0.1821
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0712 0.318 0.3165
Loa Loa (eye worm) hypothetical protein 0.0113 0.0022 0.0009
Loa Loa (eye worm) hypothetical protein 0.0274 0.087 0.0928
Echinococcus multilocularis epidermal growth factor receptor 0.0499 0.2057 0.2486
Trypanosoma cruzi Protein kinase B 0.0331 0.1169 0.1818
Echinococcus multilocularis hypothetical protein 0.0201 0.0487 0.0588
Loa Loa (eye worm) CMGC/SRPK protein kinase 0.0168 0.0311 0.0322
Schistosoma mansoni hypothetical protein 0.0221 0.0589 0.1142
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0611 0.2647 0.32
Trichomonas vaginalis CMGC family protein kinase 0.0169 0.0318 0.1227
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0194 0.045 0.0472
Brugia malayi hypothetical protein 0.0442 0.1758 0.189
Schistosoma mansoni vav2 0.0213 0.0551 0.1067
Leishmania major protein kinase, putative 0.0171 0.0327 0.0117
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.0112 0.0015 0.0001
Entamoeba histolytica casein kinase 1, putative 0.0218 0.0577 0.1651
Schistosoma mansoni protein kinase 0.086 0.3961 0.7678
Brugia malayi protein-tyrosine kinase 0.0375 0.1404 0.1506
Loa Loa (eye worm) TK protein kinase 0.0562 0.2388 0.2571
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.0462 0.1861 0.2001
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.1188 0.5689 0.6147
Schistosoma mansoni serine/threonine protein kinase 0.027 0.0847 0.1642
Trichomonas vaginalis CMGC family protein kinase 0.0278 0.0892 0.3462
Trichomonas vaginalis CAMK family protein kinase 0.018 0.0377 0.1456
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0203 0.0496 0.0522
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0203 0.0496 0.1078
Brugia malayi p21/Cdc42/Rac1-activated kinase 0.0112 0.0015 0.0001
Trichomonas vaginalis CAMK family protein kinase 0.0231 0.0644 0.2496
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.1316 0.6363 1
Echinococcus granulosus cyclin dependent kinase 0.0238 0.0683 0.0662
Trypanosoma cruzi aurora B kinase, putative 0.0291 0.096 0.1489
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.0511 0.2119 0.228
Schistosoma mansoni protein kinase 0.0306 0.104 0.2016
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.04 0.1535 0.1648
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0273 0.0863 0.7923
Trichomonas vaginalis AGC family protein kinase 0.0127 0.0095 0.0362
Echinococcus multilocularis protein tyrosine kinase 0.1088 0.5159 0.6236
Plasmodium vivax multidomain scavenger receptor, putative 0.0119 0.0054 0.0039
Trichomonas vaginalis AGC family protein kinase 0.0127 0.0095 0.0362
Echinococcus multilocularis serine:threonine protein kinase 0.0229 0.0634 0.0766
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.0782 0.3548 0.3828
Echinococcus granulosus RUN 0.0119 0.0054 0.0032
Loa Loa (eye worm) hypothetical protein 0.0113 0.0022 0.0009
Plasmodium falciparum tyrosine kinase-like protein, putative 0.0164 0.0289 0.2303
Echinococcus granulosus serine:threonine protein kinase 3 0.0511 0.2119 0.2101
Trichomonas vaginalis CMGC family protein kinase 0.0201 0.0488 0.189
Plasmodium falciparum casein kinase 1 0.0218 0.0577 0.5117
Schistosoma mansoni tyrosine kinase 0.0456 0.1832 0.3551
Giardia lamblia Kinase, CMGC GSK 0.0258 0.0785 0.2435
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0371 0.138 0.136
Loa Loa (eye worm) hypothetical protein 0.0131 0.0116 0.011
Schistosoma mansoni serine/threonine protein kinase 0.0307 0.1045 0.2026
Trypanosoma brucei SNF1-related protein kinases, putative 0.018 0.0377 0.0198
Echinococcus granulosus tyrosine protein kinase 0.0562 0.2388 0.237
Entamoeba histolytica protein kinase domain containing protein 0.0201 0.0488 0.1387
Schistosoma mansoni protein kinase 0.0157 0.0256 0.0496
Echinococcus granulosus calcium:calmodulin dependent protein kinase I 0.0144 0.0183 0.0161
Trichomonas vaginalis CMGC family protein kinase 0.0278 0.0892 0.3462
Schistosoma mansoni tyrosine kinase 0.0274 0.0868 0.1683
Echinococcus granulosus roundabout 2 0.0257 0.0779 0.0758
Echinococcus multilocularis cyclin dependent kinase 0.0238 0.0683 0.0825
Schistosoma mansoni hypothetical protein 0.0201 0.0487 0.0943
Trichomonas vaginalis CAMK family protein kinase 0.018 0.0377 0.1456
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0335 0.1194 0.1174
Giardia lamblia Kinase, CMGC CDK 0.0238 0.0683 0.1907
Loa Loa (eye worm) TK protein kinase 0.0375 0.1404 0.1506
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0258 0.0785 0.1213
Echinococcus multilocularis casein kinase I delta 0.0218 0.0577 0.0698
Echinococcus granulosus NDR protein kinase 0.0335 0.1194 0.1174
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0186 0.0405 0.0384
Brugia malayi hypothetical protein 0.0119 0.0054 0.0044
Echinococcus granulosus casein kinase I alpha 0.0218 0.0577 0.0556
Trichomonas vaginalis CMGC family protein kinase 0.0169 0.0318 0.1227
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0221 0.0589 0.1142
Loa Loa (eye worm) hypothetical protein 0.0119 0.0054 0.0044
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0169 0.0318 0.0277
Schistosoma mansoni GTPase activating protein 0.0113 0.0022 0.0044
Schistosoma mansoni protein kinase 0.0174 0.0341 0.0662
Plasmodium falciparum serine/threonine protein kinase, putative 0.0291 0.096 0.8866
Echinococcus multilocularis rac serine:threonine kinase 0.0331 0.1169 0.1413
Echinococcus multilocularis nervana 2 0.0244 0.0713 0.0862
Plasmodium vivax unspecified product 0.0201 0.0488 0.427
Plasmodium vivax casein kinase 1, putative 0.0218 0.0577 0.5136
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.1316 0.6363 1
Giardia lamblia Kinase, CMGC CK2 0.0201 0.0488 0.0909
Loa Loa (eye worm) camk/dcamkl protein kinase 0.0302 0.1016 0.1085
Trichomonas vaginalis CMGC family protein kinase 0.0201 0.0488 0.189
Echinococcus multilocularis Polycystic kidney disease protein 0.0119 0.0054 0.0065
Loa Loa (eye worm) hypothetical protein 0.0221 0.0589 0.0623
Echinococcus multilocularis mitogen activated protein kinase 3 0.0169 0.0318 0.0384
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.0112 0.0015 0.0001
Echinococcus multilocularis casein kinase I alpha 0.0218 0.0577 0.0698
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0433 0.1711 0.1838
Onchocerca volvulus 0.0382 0.1441 0.334
Echinococcus granulosus serine:threonine protein kinase 0.0229 0.0634 0.0613
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0291 0.096 0.887
Schistosoma mansoni tensin-related 0.0113 0.0022 0.0044
Echinococcus multilocularis casein kinase i 0.0218 0.0577 0.0698
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.014 0.0163 0.0162
Trichomonas vaginalis STE family protein kinase 0.0131 0.0116 0.0442
Schistosoma mansoni tensin 0.0113 0.0022 0.0044
Giardia lamblia Kinase, NEK 0.0273 0.0863 0.2834
Entamoeba histolytica PH domain containing protein kinase, putative 0.0245 0.0715 0.2064
Schistosoma mansoni serine/threonine protein kinase 0.0168 0.0311 0.0603
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0227 0.0622 0.0601
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0258 0.0785 0.2379
Trypanosoma cruzi polo-like protein kinase, putative 0.0537 0.2258 0.3534
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.018 0.0377 0.0198
Loa Loa (eye worm) hypothetical protein 0.0238 0.0682 0.0724
Echinococcus granulosus insulin receptor 0.0439 0.1742 0.1723
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0147 0.0202 0.0204
Echinococcus multilocularis lipoxygenase domain containing protein 0.0119 0.0054 0.0065
Entamoeba histolytica protein kinase domain containing protein 0.0245 0.0718 0.2072
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.086 0.3961 0.3947
Echinococcus granulosus tyrosine protein kinase Fyn 0.0456 0.1832 0.1813
Brugia malayi Protein kinase domain containing protein 0.0181 0.038 0.0397
Schistosoma mansoni serine/threonine protein kinase 0.0591 0.2543 0.4929
Loa Loa (eye worm) TK/FER protein kinase 0.0202 0.0489 0.0515
Schistosoma mansoni vam6/vps39 related 0.0221 0.0589 0.1142
Echinococcus multilocularis serine:threonine protein kinase 0.0229 0.0634 0.0766
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.1188 0.5689 0.6147
Plasmodium falciparum calcium-dependent protein kinase 5 0.0203 0.0496 0.4322
Schistosoma mansoni titin 0.014 0.0163 0.0316
Toxoplasma gondii histone kinase SNF1, putative 0.018 0.0377 0.0542
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0218 0.0577 0.061
Entamoeba histolytica serine/threonine protein kinase, putative 0.0537 0.2258 0.6658
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0164 0.0289 0.015
Trichomonas vaginalis CAMK family protein kinase 0.018 0.0377 0.1456
Schistosoma mansoni hypothetical protein 0.0113 0.0022 0.0044
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0258 0.0785 0.0836
Leishmania major protein kinase, putative 0.0307 0.1045 0.1292
Brugia malayi putative serine/threonine kinase SADA gamma 0.018 0.0377 0.0393
Trichomonas vaginalis AGC family protein kinase 0.0127 0.0095 0.0362
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0227 0.0622 0.0601
Entamoeba histolytica protein kinase, putative 0.0245 0.0718 0.2072
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.1863 0.9246 1
Echinococcus granulosus epidermal growth factor receptor 0.0362 0.1335 0.1315
Brugia malayi protein kinase C II. 0.042 0.1642 0.1764
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0238 0.0683 0.0724
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.048 0.1956 0.1938
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.0278 0.0892 0.0952
Echinococcus multilocularis casein kinase I alpha 0.0218 0.0577 0.0698
Giardia lamblia Kinase, CK1 Casein kinase 0.0218 0.0577 0.1365
Echinococcus multilocularis protein kinase shaggy 0.0258 0.0785 0.0949
Giardia lamblia Kinase, STE STE20 0.0171 0.0327 0.0083
Brugia malayi Immunoglobulin I-set domain containing protein 0.052 0.2166 0.2331
Leishmania major protein kinase, putative 0.0307 0.1045 0.1292
Entamoeba histolytica protein kinase, putative 0.0174 0.0341 0.095
Schistosoma mansoni suppressor of cytokine signaling 0.0113 0.0022 0.0044
Echinococcus multilocularis roundabout 2 0.0257 0.0779 0.0942
Plasmodium falciparum calcium-dependent protein kinase 1 0.0203 0.0496 0.4322
Loa Loa (eye worm) hypothetical protein 0.0203 0.0496 0.0522
Echinococcus granulosus expressed protein 0.0404 0.1554 0.1535
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0158 0.026 0.0314
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0307 0.1045 0.1622
Echinococcus granulosus maternal embryonic leucine zipper kinase 0.0231 0.0644 0.0623
Schistosoma mansoni hypothetical protein 0.0113 0.0022 0.0044
Loa Loa (eye worm) hypothetical protein 0.0119 0.0054 0.0044
Echinococcus granulosus growth factor receptor bound protein 2 0.0198 0.0471 0.0449
Loa Loa (eye worm) SH2 domain-containing protein 0.0113 0.0022 0.0009
Trichomonas vaginalis AGC family protein kinase 0.0376 0.1406 0.5462
Trichomonas vaginalis CAMK family protein kinase 0.018 0.0377 0.1456
Brugia malayi Protein kinase domain containing protein 0.11 0.5221 0.5641
Brugia malayi Protein kinase domain containing protein 0.0165 0.0294 0.0304
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0371 0.138 0.1668
Echinococcus granulosus insulin growth factor 1 receptor beta 0.047 0.1905 0.1886
Loa Loa (eye worm) hypothetical protein 0.0201 0.0487 0.0512
Brugia malayi p70 ribosomal S6 kinase beta 0.0579 0.248 0.2672
Echinococcus multilocularis tyrosine protein kinase Blk 0.0375 0.1404 0.1697
Entamoeba histolytica protein kinase, putative 0.0148 0.0209 0.0555
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.0442 0.1758 0.2126
Onchocerca volvulus 0.0274 0.087 0.1997
Echinococcus multilocularis 0.0113 0.0022 0.0027
Onchocerca volvulus 0.0158 0.0259 0.0557
Toxoplasma gondii AGC kinase 0.0579 0.248 1
Trichomonas vaginalis CAMK family protein kinase 0.018 0.0377 0.1456
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0289 0.0952 0.1151
Echinococcus multilocularis protein kinase c epsilon type 0.042 0.1642 0.1985
Brugia malayi Protein kinase domain containing protein 0.0202 0.0489 0.0515
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0171 0.0327 0.0492
Echinococcus multilocularis activin receptor type 0.0157 0.0256 0.0309
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0203 0.0496 0.1078
Echinococcus granulosus calcium activated potassium channel 0.027 0.0849 0.0829
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0291 0.096 0.2792
Echinococcus granulosus MAP kinase activated protein kinase 2 0.0782 0.3548 0.3533
Schistosoma mansoni serine/threonine protein kinase 0.0425 0.1665 0.3228
Echinococcus multilocularis homeodomain interacting protein kinase 3 0.0404 0.1555 0.1879
Schistosoma mansoni protein kinase 0.0291 0.096 0.1861
Echinococcus granulosus CDC7 cell division cycle 7 0.0181 0.038 0.0359
Loa Loa (eye worm) hypothetical protein 0.0226 0.0616 0.0652
Onchocerca volvulus 0.014 0.0163 0.0331
Trichomonas vaginalis AGC family protein kinase 0.0127 0.0095 0.0362
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.1316 0.6363 1
Loa Loa (eye worm) AUR protein kinase 0.0291 0.096 0.1025
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0227 0.0622 0.0752
Echinococcus granulosus phosphorylase kinase gamma subunit 0.0328 0.1154 0.1134
Trypanosoma cruzi casein kinase, putative 0.0218 0.0577 0.0885
Loa Loa (eye worm) TK protein kinase 0.052 0.2166 0.2331
Brugia malayi Casein kinase II, alpha chain 0.0201 0.0488 0.0514
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0313 0.1076 0.1671
Trichomonas vaginalis CAMK family protein kinase 0.0537 0.2258 0.8775
Loa Loa (eye worm) hypothetical protein 0.0184 0.0398 0.0416
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.1316 0.6363 1
Schistosoma mansoni serine/threonine protein kinase 0.043 0.1694 0.3283
Loa Loa (eye worm) hypothetical protein 0.0226 0.0616 0.0652
Schistosoma mansoni serine/threonine protein kinase 0.018 0.0377 0.073
Echinococcus multilocularis tyrosine protein kinase 0.0562 0.2388 0.2886
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0351 0.1275 0.1367
Trypanosoma cruzi casein kinase, putative 0.0218 0.0577 0.0885
Schistosoma mansoni serine/threonine protein kinase 0.0525 0.2196 0.4257
Loa Loa (eye worm) hypothetical protein 0.0712 0.3179 0.3428
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0291 0.096 0.2792
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0221 0.0589 0.0545
Schistosoma mansoni serine/threonine protein kinase 0.0468 0.1892 0.3667
Echinococcus granulosus tyrosine kinase 0.0202 0.0489 0.0468
Schistosoma mansoni tyrosine kinase 0.0456 0.1832 0.3551
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0313 0.1076 0.1056
Schistosoma mansoni lipoxygenase 0.0498 0.2051 0.3975
Toxoplasma gondii cell-cycle-associated protein kinase SRPK, putative 0.0168 0.0311 0.0248
Onchocerca volvulus 0.0202 0.0489 0.1099
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0227 0.0622 0.0957
Trichomonas vaginalis CMGC family protein kinase 0.0201 0.0488 0.189
Plasmodium vivax protein kinase Crk2 0.0238 0.0683 0.6165
Entamoeba histolytica protein kinase, putative 0.0168 0.0311 0.086
Trichomonas vaginalis AGC family protein kinase 0.0335 0.1194 0.4634
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0313 0.1076 1
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0157 0.0256 0.0309
Schistosoma mansoni serine/threonine protein kinase 0.0499 0.2055 0.3983
Echinococcus granulosus tyrosine protein kinase Src42A 0.0456 0.1832 0.1813
Loa Loa (eye worm) hypothetical protein 0.0184 0.0398 0.0416
Echinococcus multilocularis SH2 domain containing adapter protein F 0.0113 0.0022 0.0027
Trichomonas vaginalis CK1 family protein kinase 0.0218 0.0577 0.2236
Giardia lamblia Kinase, AGC PKA 0.0227 0.0622 0.1599
Schistosoma mansoni serine/threonine-protein kinase 0.0331 0.1169 0.2266
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0203 0.0496 0.4344
Schistosoma mansoni ephrin receptor 0.0119 0.0056 0.0109
Toxoplasma gondii CMGC kinase, CK2 family 0.0201 0.0488 0.1043
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0203 0.0496 0.0474
Schistosoma mansoni tensin 0.0113 0.0022 0.0044
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0238 0.0683 0.0724
Echinococcus granulosus Polycystic kidney disease protein 0.0119 0.0054 0.0032
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0203 0.0496 0.0599
Brugia malayi protein kinase C3,putative 0.0315 0.1087 0.1163
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0227 0.0622 0.06
Trichomonas vaginalis AGC family protein kinase 0.0393 0.1499 0.5823
Brugia malayi Sex muscle abnormal protein 5 0.0194 0.045 0.0472
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.042 0.1642 0.1764
Giardia lamblia Kinase, CMGC CLK 0.0307 0.1045 0.3769
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0371 0.138 0.1479
Schistosoma mansoni vesicular amine transporter 0.0153 0.0235 0.0455
Schistosoma mansoni tyrosine kinase 0.0283 0.0917 0.1777
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0227 0.0622 0.5562
Brugia malayi serine/threonine protein kinase 6 0.0291 0.096 0.1025
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0227 0.0622 0.06
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0227 0.0622 0.5579
Brugia malayi Temporarily assigned gene name protein 59 0.0255 0.0769 0.0818
Loa Loa (eye worm) hypothetical protein 0.0113 0.0022 0.0009
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0335 0.1194 0.1443
Trypanosoma cruzi casein kinase, putative 0.0218 0.0577 0.0885
Brugia malayi SH2 domain containing protein 0.0113 0.0022 0.0009
Echinococcus granulosus cGMP dependent protein kinase 0.027 0.0847 0.0826
Echinococcus multilocularis PAK box P21 Rho binding 0.0131 0.0116 0.014
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0376 0.1406 0.1508
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0245 0.0718 0.1108
Trichomonas vaginalis CMGC family protein kinase 0.0201 0.0488 0.189
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0307 0.1045 0.1117
Entamoeba histolytica protein kinase, putative 0.0203 0.0496 0.1409
Entamoeba histolytica protein kinase, putative 0.0579 0.248 0.7319
Loa Loa (eye worm) casein kinase 0.0356 0.1302 0.1395
Schistosoma mansoni serine/threonine protein kinase 0.027 0.0847 0.1642
Echinococcus granulosus mitogen activated protein kinase 3 0.0169 0.0318 0.0296
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0375 0.1404 0.1697
Entamoeba histolytica cell division protein kinase 2, putative 0.0238 0.0683 0.1966
Brugia malayi hypothetical protein 0.0221 0.0589 0.0623
Trichomonas vaginalis CMGC family protein kinase 0.0307 0.1045 0.4056
Brugia malayi Variant SH3 domain containing protein 0.0194 0.045 0.0472
Brugia malayi Immunoglobulin I-set domain containing protein 0.1065 0.5037 0.5441
Trichomonas vaginalis AGC family protein kinase 0.0597 0.2573 1
Loa Loa (eye worm) TK/FER protein kinase 0.0801 0.3645 0.3934
Brugia malayi Protein kinase domain containing protein 0.0229 0.0634 0.0672
Schistosoma mansoni tensin-related 0.0113 0.0022 0.0044
Echinococcus multilocularis tensin 0.0113 0.0022 0.0027
Brugia malayi Tensin 0.0113 0.0022 0.0009
Brugia malayi protein unc-22 0.014 0.0163 0.0162
Echinococcus granulosus casein kinase I delta 0.0218 0.0577 0.0556
Onchocerca volvulus 0.0181 0.038 0.0843
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0273 0.0863 0.2729
Schistosoma mansoni tyrosine-protein kinase zap-70 0.0113 0.0022 0.0044
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0157 0.0256 0.0234
Loa Loa (eye worm) CAMK/PHK protein kinase 0.0328 0.1154 0.1235
Schistosoma mansoni tyrosine kinase 0.1088 0.5159 1
Schistosoma mansoni tyrosine kinase 0.0439 0.1742 0.3376
Plasmodium vivax serine/threonine protein kinase, putative 0.0168 0.0311 0.2545
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.1316 0.6363 0.6877
Echinococcus multilocularis SH2 motif 0.0113 0.0022 0.0027
Trichomonas vaginalis AGC family protein kinase 0.0376 0.1406 0.5462
Trichomonas vaginalis CAMK family protein kinase 0.018 0.0377 0.1456
Schistosoma mansoni rap gtpase-activating protein 0.0221 0.0589 0.1142
Onchocerca volvulus 0.0202 0.0489 0.1099
Trichomonas vaginalis CMGC family protein kinase 0.0238 0.0683 0.2646
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0227 0.0622 0.06
Brugia malayi Doublecortin family protein 0.0302 0.1016 0.1085
Brugia malayi hypothetical protein 0.0119 0.0054 0.0044
Plasmodium falciparum calcium-dependent protein kinase 3 0.0203 0.0496 0.4322
Brugia malayi Protein kinase domain containing protein 0.023 0.064 0.0678
Brugia malayi Serine/threonine-protein kinase Pim-3 0.07 0.3115 0.3359
Trichomonas vaginalis AGC family protein kinase 0.0291 0.096 0.3726
Loa Loa (eye worm) TK/FER protein kinase 0.0202 0.0489 0.0515
Schistosoma mansoni protein kinase 0.0527 0.2202 0.4269
Brugia malayi cell division control protein 2 homolog 0.0238 0.0683 0.0724
Entamoeba histolytica protein kinase, putative 0.0291 0.096 0.2792
Schistosoma mansoni protein kinase 0.0201 0.0488 0.0946
Echinococcus multilocularis myosin iiia 0.0171 0.0327 0.0396
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0238 0.0683 0.0698
Brugia malayi serine/threonine-protein kinase PAK 7 0.0462 0.1861 0.2001
Echinococcus multilocularis SH2 motif 0.0113 0.0022 0.0027
Echinococcus granulosus fibroblast growth factor receptor 4 0.048 0.1956 0.1938
Schistosoma mansoni serine/threonine protein kinase 0.0328 0.1154 0.2236
Brugia malayi Protein kinase domain containing protein 0.0202 0.0489 0.0515
Trichomonas vaginalis CAMK family protein kinase 0.0432 0.1704 0.6618
Echinococcus multilocularis calcium activated potassium channel 0.027 0.0849 0.1027
Echinococcus granulosus serine/threonine protein kinase 0.0331 0.1169 0.1149
Entamoeba histolytica protein kinase domain containing protein 0.0404 0.1555 0.4562
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0196 0.0458 0.0553
Trichomonas vaginalis AGC family protein kinase 0.0127 0.0095 0.0362
Echinococcus granulosus tyrosine protein kinase Blk 0.0375 0.1404 0.1385
Onchocerca volvulus 0.079 0.3592 0.8406
Echinococcus multilocularis epidermal growth factor receptor 0.0362 0.1335 0.1613
Echinococcus granulosus calcium dependent protein kinase 0.0134 0.0133 0.0111
Echinococcus multilocularis c src tyrosine kinase 0.0283 0.0917 0.1108
Plasmodium vivax glycogen synthase kinase 3, putative 0.0258 0.0785 0.7165
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0579 0.248 0.2672
Echinococcus multilocularis Immunoglobulin 0.0153 0.0235 0.0284
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0218 0.0577 0.0885
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0174 0.0341 0.0413
Plasmodium falciparum calcium-dependent protein kinase 2 0.0203 0.0496 0.4322
Brugia malayi ribosomal protein S6 kinase alpha 3 0.0235 0.0665 0.0705
Brugia malayi hypothetical protein 0.0113 0.0022 0.0009
Brugia malayi Immunoglobulin I-set domain containing protein 0.0184 0.0398 0.0416
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.0278 0.0892 0.2861
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0456 0.1832 0.2214
Echinococcus granulosus NCK adaptor protein 0.0194 0.045 0.0428
Loa Loa (eye worm) TK/FER protein kinase 0.0202 0.0489 0.0515
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0113 0.0022 0.0009
Schistosoma mansoni serine/threonine protein kinase 0.0404 0.1555 0.3014
Echinococcus multilocularis ephrin type A receptor 4 A 0.0215 0.0559 0.0676
Echinococcus granulosus casein kinase ii subunit alpha 0.0201 0.0488 0.0467
Onchocerca volvulus 0.0202 0.0489 0.1099
Brugia malayi tRNA modification GTPase TrmE family protein 0.0113 0.0022 0.0009
Toxoplasma gondii AGC kinase 0.0227 0.0622 0.1647
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0221 0.0589 0.0904
Brugia malayi Protein kinase domain containing protein 0.0889 0.4113 0.444
Loa Loa (eye worm) hypothetical protein 0.0194 0.045 0.0472
Loa Loa (eye worm) SH2 domain-containing protein 0.0113 0.0022 0.0009
Echinococcus multilocularis dual specificity 0.0278 0.0892 0.1079
Trypanosoma brucei casein kinase I, isoform 2 0.0218 0.0577 0.0526
Loa Loa (eye worm) hypothetical protein 0.0113 0.0022 0.0009
Echinococcus granulosus serine threonine protein kinase nrc 0.0313 0.1076 0.1056
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0307 0.1045 0.1622
Schistosoma mansoni serine/threonine protein kinase 0.0232 0.0647 0.1254
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0169 0.0318 0.0329
Trichomonas vaginalis CMGC family protein kinase 0.0278 0.0892 0.3462
Schistosoma mansoni serine/threonine protein kinase 0.0307 0.1045 0.2026

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 0.0026 uM Inhibitory activity against phosphodiesterase 5 from human platelets ChEMBL. 7658441

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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