Detailed information for compound 2078324

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 540.413 | Formula: C21H22F6N4O6
  • H donors: 3 H acceptors: 8 LogP: 0.5 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 2
  • SMILES: OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.Cn1ncc(c1)c1ncc2c(c1C(=O)O)CCN(C2)CC1CC1
  • InChi: 1S/C17H20N4O2.2C2HF3O2/c1-20-9-13(7-19-20)16-15(17(22)23)14-4-5-21(8-11-2-3-11)10-12(14)6-18-16;2*3-2(4,5)1(6)7/h6-7,9,11H,2-5,8,10H2,1H3,(H,22,23);2*(H,6,7)
  • InChiKey: DZGGVOQDNTWSLR-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0039 0.0088 0.0087
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0039 0.0156
Echinococcus multilocularis FTZ F1 alpha 0.0014 0.0011 0.001
Echinococcus multilocularis neuropeptide receptor 0.0039 0.0088 0.0087
Brugia malayi Cathepsin L-like precursor 0.002 0.003 0.0036
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0017 0.0022 0.0541
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0014 0.0011 0.001
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0028 0.0053 0.1311
Echinococcus granulosus rhodopsin orphan GPCR 0.0039 0.0088 0.0087
Schistosoma mansoni tar DNA-binding protein 0.0132 0.0367 0.0366
Loa Loa (eye worm) hypothetical protein 0.0039 0.0088 0.0105
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0028 0.0053 0.0052
Schistosoma mansoni neuropeptide receptor 0.0039 0.0088 0.0087
Loa Loa (eye worm) G-protein coupled receptor 0.0039 0.0088 0.0105
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.003 0.0119
Leishmania major hypothetical protein, conserved 0.0017 0.0022 0.0341
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0039 0.0088 0.0087
Loa Loa (eye worm) hypothetical protein 0.0039 0.0088 0.0105
Brugia malayi follicle stimulating hormone receptor 0.0039 0.0088 0.0106
Mycobacterium ulcerans Type I modular polyketide synthase 0.0052 0.0125 0.3037
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsB 0.0042 0.0095 0.2245
Trichomonas vaginalis penicillin-binding protein, putative 0.014 0.0393 0.1595
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0029 0.0058 0.1469
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0726 0.2158 0.2631
Mycobacterium tuberculosis Probable conserved lipoprotein 0.014 0.0393 0.1445
Mycobacterium tuberculosis Probable oxidoreductase 0.0203 0.058 0.2148
Schistosoma mansoni coup transcription factor 0.0014 0.0011 0.001
Schistosoma mansoni ferritin 0.0016 0.0017 0.0016
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0039 0.0088 0.0105
Plasmodium vivax hypothetical protein, conserved 0.0033 0.0068 0.172
Echinococcus granulosus dnaJ subfamily B 0.0305 0.089 0.089
Trichomonas vaginalis CAMK family protein kinase 0.007 0.018 0.073
Brugia malayi Latrophilin receptor protein 2 0.0239 0.0691 0.0842
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0028 0.0053 0.0052
Trichomonas vaginalis bromodomain-containing protein, putative 0.0029 0.0058 0.0234
Onchocerca volvulus Protein ultraspiracle homolog 0.0014 0.0011 0.0043
Echinococcus multilocularis neuropeptide s receptor 0.0039 0.0088 0.0087
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.003 0.0119
Onchocerca volvulus 0.002 0.003 0.0121
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0059 0.0146 0.0146
Schistosoma mansoni RAR-like nuclear receptor 0.0014 0.0011 0.001
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0105 0.0285 0.0284
Schistosoma mansoni survival motor neuron protein 0.003 0.006 0.0059
Plasmodium vivax flap endonuclease 1, putative 0.0019 0.0028 0.0704
Schistosoma mansoni hypothetical protein 0.0111 0.0304 0.0304
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.003 0.0119
Brugia malayi hypothetical protein 0.0039 0.0088 0.0106
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0039 0.0088 0.0087
Giardia lamblia Histone acetyltransferase GCN5 0.0023 0.0039 0.0644
Echinococcus multilocularis sex peptide receptor 0.0039 0.0088 0.0087
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.014 0.0393 0.0478
Mycobacterium ulcerans Type I modular polyketide synthase 0.0052 0.0125 0.3037
Echinococcus granulosus neuropeptides capa receptor 0.0039 0.0088 0.0087
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0013 0.001 0.0038
Schistosoma mansoni biogenic amine (5HT) receptor 0.0636 0.1888 0.1887
Trichomonas vaginalis ran, putative 0.0059 0.0146 0.0593
Echinococcus granulosus g-protein coupled receptor 0.0039 0.0088 0.0087
Echinococcus multilocularis g protein coupled receptor 0.0039 0.0088 0.0087
Loa Loa (eye worm) hypothetical protein 0.014 0.0393 0.0478
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.009 0.0241 0.0241
Loa Loa (eye worm) beta-lactamase 0.014 0.0393 0.0478
Brugia malayi neuropeptide F receptor 0.0039 0.0088 0.0106
Loa Loa (eye worm) MH2 domain-containing protein 0.1536 0.46 0.5609
Echinococcus multilocularis rhodopsin orphan GPCR 0.0039 0.0088 0.0087
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0052 0.0125 0.0442
Echinococcus granulosus importin subunit beta 1 0.009 0.0241 0.0241
Echinococcus multilocularis somatostatin receptor 0.0039 0.0088 0.0087
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.014 0.0393 1
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0052 0.0127 0.3088
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0039 0.0088 0.0087
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0039 0.0088 0.0105
Trypanosoma cruzi cysteine peptidase, putative 0.002 0.003 0.0744
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSB 0.0042 0.0095 0.1384
Mycobacterium tuberculosis Probable polyketide synthase Pks7 0.0055 0.0135 0.0478
Echinococcus granulosus fmrfamide receptor 0.0039 0.0088 0.0087
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0017 0.0021 0.0021
Brugia malayi hypothetical protein 0.041 0.1204 0.1468
Onchocerca volvulus 0.0039 0.0088 0.0356
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0028 0.0053 0.1338
Schistosoma mansoni tar DNA-binding protein 0.0132 0.0367 0.0366
Toxoplasma gondii kinesin motor domain-containing protein 0.0017 0.002 0.0455
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.003 0.0119
Echinococcus granulosus g protein coupled receptor 0.0039 0.0088 0.0087
Loa Loa (eye worm) hypothetical protein 0.0039 0.0088 0.0105
Brugia malayi nuclear hormone receptor 0.0014 0.0011 0.0012
Plasmodium vivax thioredoxin reductase, putative 0.008 0.021 0.535
Brugia malayi Papain family cysteine protease containing protein 0.002 0.003 0.0036
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0014 0.0013 0.005
Echinococcus multilocularis kinesin family 1 0.0128 0.0354 0.0354
Mycobacterium leprae PROBABLE FATTY ACID SYNTHASE FAS (FATTY ACID SYNTHETASE) 0.0016 0.0019 0.0027
Echinococcus granulosus rhodopsin orphan GPCR 0.0039 0.0088 0.0087
Brugia malayi Cathepsin L-like precursor 0.002 0.003 0.0036
Echinococcus multilocularis lysine specific demethylase 6a 0.0017 0.0022 0.0021
Echinococcus granulosus TGF beta signal transducer SmadC 0.0105 0.0285 0.0284
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0059 0.0146 0.3719
Loa Loa (eye worm) hypothetical protein 0.0039 0.0088 0.0105
Brugia malayi Kinesin motor domain containing protein 0.0017 0.002 0.0023
Echinococcus multilocularis orexin receptor type 2 0.0039 0.0088 0.0087
Brugia malayi Cathepsin L-like precursor 0.002 0.003 0.0036
Echinococcus multilocularis g protein coupled receptor 0.0039 0.0088 0.0087
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0014 0.0011 0.0012
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0028 0.0053 0.1338
Plasmodium falciparum transportin 0.0017 0.0021 0.0848
Mycobacterium leprae Probable polyketide synthase Pks1 0.0055 0.0135 0.2096
Toxoplasma gondii thioredoxin reductase 0.008 0.021 0.5336
Echinococcus multilocularis cpg binding protein 0.0026 0.0048 0.0047
Giardia lamblia Kinase, PLK 0.0133 0.0372 1
Schistosoma mansoni opsin-like receptor 0.0039 0.0088 0.0087
Echinococcus granulosus fetal alzheimer antigen falz 0.004 0.0092 0.0091
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0132 0.0367 0.0446
Brugia malayi AMP-binding enzyme family protein 0.0016 0.0017 0.0021
Brugia malayi Methyltransferase-like protein 4 0.0016 0.0017 0.0019
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0039 0.0088 0.0087
Loa Loa (eye worm) hypothetical protein 0.0013 0.001 0.0011
Schistosoma mansoni thyroid hormone receptor 0.0014 0.0011 0.001
Loa Loa (eye worm) hypothetical protein 0.0015 0.0015 0.0018
Mycobacterium tuberculosis Probable fatty acid synthase Fas (fatty acid synthetase) 0.0016 0.0019 0.0041
Schistosoma mansoni flap endonuclease-1 0.0018 0.0023 0.0022
Echinococcus multilocularis dro:myosuppressin receptor 0.0039 0.0088 0.0087
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0039 0.0088 0.0087
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0029 0.0058 0.1443
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0059 0.0146 0.3719
Schistosoma mansoni smad1 5 8 and 0.0105 0.0285 0.0284
Echinococcus granulosus neuropeptide Y receptor 0.0039 0.0088 0.0087
Brugia malayi hypothetical protein 0.007 0.018 0.0218
Loa Loa (eye worm) hypothetical protein 0.0039 0.0088 0.0105
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0039 0.0088 0.0106
Loa Loa (eye worm) TYRA-2 protein 0.0039 0.0088 0.0105
Echinococcus granulosus MAP kinase activated protein kinase 2 0.273 0.8199 0.8199
Echinococcus multilocularis ecdysone induced protein 78C 0.0014 0.0011 0.001
Onchocerca volvulus Neuropeptide F receptor homolog 0.0039 0.0088 0.0356
Echinococcus multilocularis cathepsin l cysteine peptidase 0.002 0.003 0.0029
Onchocerca volvulus 0.014 0.0393 0.1597
Brugia malayi hypothetical protein 0.0039 0.0088 0.0106
Loa Loa (eye worm) hypothetical protein 0.0039 0.0088 0.0105
Brugia malayi PHD-finger family protein 0.0047 0.011 0.0134
Echinococcus multilocularis translational activator gcn1 0.0017 0.0021 0.002
Echinococcus multilocularis mothers against decapentaplegic 6 0.0047 0.0111 0.011
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0014 0.0011 0.0012
Echinococcus granulosus thioredoxin glutathione reductase 0.008 0.0212 0.0212
Schistosoma mansoni hypothetical protein 0.0239 0.0691 0.0691
Echinococcus multilocularis neuropeptide Y receptor 0.0039 0.0088 0.0087
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0182 0.0519 0.1918
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.003 0.0119
Onchocerca volvulus Cathepsin L homolog 0.002 0.003 0.0121
Schistosoma mansoni hypothetical protein 0.0039 0.0088 0.0087
Onchocerca volvulus 0.0039 0.0088 0.0356
Echinococcus multilocularis mothers against decapentaplegic 2 0.0047 0.0111 0.011
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0059 0.0146 0.37
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0028 0.0053 1
Loa Loa (eye worm) MH2 domain-containing protein 0.0105 0.0285 0.0346
Schistosoma mansoni peptidase 0.0014 0.0012 0.0012
Entamoeba histolytica cysteine proteinase, putative 0.001 0.0001 0.0011
Brugia malayi AMP-binding enzyme family protein 0.0048 0.0115 0.014
Loa Loa (eye worm) hypothetical protein 0.0073 0.019 0.023
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0028 0.0053 0.1338
Trypanosoma brucei beta-ketoacyl-ACP synthase 0.0013 0.0009 0.0207
Brugia malayi jmjC domain containing protein 0.0017 0.0022 0.0026
Brugia malayi hypothetical protein 0.0039 0.0088 0.0106
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0062 0.0156 0.0555
Echinococcus granulosus mothers against decapentaplegic 5 0.0105 0.0285 0.0284
Schistosoma mansoni myosin xvIII 0.0039 0.0088 0.0087
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0039 0.0088 0.0105
Loa Loa (eye worm) hypothetical protein 0.0048 0.0115 0.0138
Brugia malayi Bromodomain containing protein 0.0069 0.0177 0.0215
Echinococcus granulosus tm gpcr rhodopsin 0.0039 0.0088 0.0087
Plasmodium vivax 3-oxoacyl-[acyl-carrier-protein] synthase i/ii, putative 0.0013 0.0009 0.0207
Brugia malayi Tachykinin-like peptides receptor 99D 0.0039 0.0088 0.0106
Echinococcus granulosus tar DNA binding protein 0.0132 0.0367 0.0366
Echinococcus granulosus lysine specific demethylase 5A 0.0069 0.0179 0.0178
Schistosoma mansoni amine GPCR 0.0039 0.0088 0.0087
Giardia lamblia Flap structure-specific endonuclease 0.0019 0.0028 0.0329
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0052 0.0127 0.0154
Toxoplasma gondii type I fatty acid synthase, putative 0.0055 0.0135 0.3408
Loa Loa (eye worm) MH1 domain-containing protein 0.0105 0.0285 0.0346
Schistosoma mansoni chromobox protein 0.0058 0.0144 0.0144
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0006 0.0022
Schistosoma mansoni hypothetical protein 0.0033 0.0068 0.0067
Trichomonas vaginalis glutathione reductase, putative 0.0028 0.0053 0.0213
Echinococcus granulosus cathepsin l cysteine peptidase 0.002 0.003 0.0029
Schistosoma mansoni microtubule-associated protein tau 0.1528 0.4576 0.4576
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0039 0.0088 0.0087
Plasmodium vivax glutathione reductase, putative 0.008 0.021 0.535
Brugia malayi Dopamine receptor protein 2 0.0039 0.0088 0.0106
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0014 0.0013 0.005
Onchocerca volvulus 0.002 0.003 0.0121
Echinococcus multilocularis peregrin 0.0039 0.0087 0.0086
Schistosoma mansoni phosphatidylserine receptor 0.0017 0.0022 0.0021
Echinococcus granulosus rhodopsin orphan GPCR 0.0039 0.0088 0.0087
Onchocerca volvulus 0.0039 0.0088 0.0356
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0059 0.0146 0.6056
Brugia malayi F/Y-rich N-terminus family protein 0.0024 0.0043 0.0052
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0039 0.0088 0.0087
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0239 0.0691 0.0842
Echinococcus granulosus importin 5 0.0017 0.0021 0.002
Onchocerca volvulus 0.0039 0.0088 0.0356
Schistosoma mansoni hypothetical protein 0.0239 0.0691 0.0691
Trypanosoma brucei polo-like protein kinase 0.0133 0.0372 0.9468
Echinococcus multilocularis JmjC domain containing protein 4 0.0017 0.0022 0.0021
Loa Loa (eye worm) hypothetical protein 0.0014 0.0011 0.0012
Brugia malayi Cathepsin L-like precursor 0.002 0.003 0.0036
Echinococcus granulosus phd:f box containing protein 0.0017 0.0022 0.0021
Brugia malayi CHD4 protein 0.0014 0.0012 0.0014
Mycobacterium ulcerans fatty acid synthase Fas 0.0016 0.0019 0.0256
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.014 0.0393 0.0392
Brugia malayi MH1 domain containing protein 0.0058 0.0144 0.0175
Echinococcus multilocularis rhodopsin orphan GPCR 0.0039 0.0088 0.0087
Schistosoma mansoni hypothetical protein 0.0039 0.0088 0.0087
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0014 0.0011 0.0012
Schistosoma mansoni amine GPCR 0.0039 0.0088 0.0087
Onchocerca volvulus 0.0048 0.0115 0.0468
Schistosoma mansoni biogenic amine receptor 0.0039 0.0088 0.0087
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0017 0.0021 0.0021
Brugia malayi Tyrosine-protein kinase abl-1 0.0064 0.0163 0.0198
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0017 0.0022 0.0541
Echinococcus multilocularis rhodopsin orphan GPCR 0.0039 0.0088 0.0087
Echinococcus granulosus tyrosine protein kinase ABL1 0.0158 0.0445 0.0444
Schistosoma mansoni neuropeptide F-like receptor 0.0039 0.0088 0.0087
Plasmodium falciparum thioredoxin reductase 0.008 0.021 0.8713
Schistosoma mansoni neuropeptide F-like receptor 0.0039 0.0088 0.0087
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0017 0.0022 0.0512
Loa Loa (eye worm) ctsf protein 0.002 0.003 0.0035
Schistosoma mansoni transcription factor LCR-F1 0.0132 0.0367 0.0367
Echinococcus granulosus cathepsin l1 0.002 0.003 0.0029
Leishmania major hypothetical protein, conserved 0.0017 0.0021 0.0321
Schistosoma mansoni ferritin 0.0016 0.0017 0.0016
Brugia malayi Importin beta-1 subunit 0.009 0.0241 0.0294
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0028 0.0053 0.1155
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.003 0.0119
Entamoeba histolytica cysteine protease, putative 0.001 0.0001 0.0011
Onchocerca volvulus 0.0025 0.0046 0.0188
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0052 0.0127 0.342
Plasmodium falciparum thioredoxin reductase 0.0028 0.0053 0.2178
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.003 0.0119
Leishmania major importin beta-1 subunit, putative 0.0073 0.019 0.472
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0014 0.0011 0.001
Treponema pallidum fructose-bisphosphate aldolase 0.0126 0.035 1
Brugia malayi hypothetical protein 0.0039 0.0088 0.0106
Echinococcus granulosus flap endonuclease 1 0.0019 0.0028 0.0028
Loa Loa (eye worm) acetyltransferase 0.009 0.0241 0.0293
Echinococcus multilocularis microtubule associated protein 2 0.1528 0.4576 0.4576
Entamoeba histolytica cysteine protease, putative 0.001 0.0001 0.0011
Loa Loa (eye worm) cysteine protease 0.002 0.003 0.0035
Onchocerca volvulus 0.0039 0.0088 0.0356
Loa Loa (eye worm) fibroinase 0.002 0.003 0.0035
Entamoeba histolytica cysteine protease, putative 0.001 0.0001 0.0011
Plasmodium falciparum importin beta, putative 0.009 0.0241 1
Echinococcus granulosus histone lysine methyltransferase setb 0.0134 0.0374 0.0374
Loa Loa (eye worm) hypothetical protein 0.0014 0.0011 0.0012
Echinococcus granulosus somatostatin receptor 0.0039 0.0088 0.0087
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.01 0.0272 0.0271
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0028 0.0053 0.0064
Loa Loa (eye worm) hypothetical protein 0.041 0.1204 0.1467
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSD 0.0052 0.0125 0.1924
Toxoplasma gondii ABC1 family protein 0.014 0.0393 1
Echinococcus multilocularis tumor protein p63 0.0988 0.2947 0.2947
Trichomonas vaginalis CAMK family protein kinase 0.0133 0.0372 0.151
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0039 0.0088 0.0087
Brugia malayi serine/threonine-protein kinase plk-2 0.0133 0.0372 0.0453
Schistosoma mansoni Smad4 0.0047 0.0111 0.011
Loa Loa (eye worm) hypothetical protein 0.014 0.0393 0.0478
Loa Loa (eye worm) hypothetical protein 0.0014 0.0011 0.0012
Echinococcus multilocularis g-protein coupled receptor 0.0039 0.0088 0.0087
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0063 0.0158 0.0158
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0039 0.0088 0.0087
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0017 0.0021 0.0021
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0028 0.0053 0.2178
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0309 0.0901 0.09
Brugia malayi hypothetical protein 0.0147 0.0412 0.0502
Loa Loa (eye worm) papain family cysteine protease containing protein 0.002 0.003 0.0035
Echinococcus multilocularis snurportin 1 0.0963 0.2872 0.2871
Brugia malayi MH2 domain containing protein 0.0105 0.0285 0.0347
Loa Loa (eye worm) kap beta 3 protein 0.0017 0.0021 0.0024
Brugia malayi hypothetical protein 0.0039 0.0088 0.0106
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0014 0.0011 0.001
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0076 0.0199 0.5053
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0028 0.0053 0.1155
Mycobacterium ulcerans esterase/lipase LipP 0.014 0.0393 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0039 0.0088 0.0087
Trichomonas vaginalis D-aminoacylase, putative 0.014 0.0393 0.1595
Loa Loa (eye worm) TK/ABL protein kinase 0.0158 0.0445 0.0541
Loa Loa (eye worm) hypothetical protein 0.0039 0.0088 0.0105
Trypanosoma cruzi cysteine peptidase, putative 0.0076 0.0199 0.5053
Entamoeba histolytica hypothetical protein 0.0073 0.019 0.5106
Loa Loa (eye worm) hypothetical protein 0.0048 0.0115 0.0138
Mycobacterium leprae conserved hypothetical protein 0.014 0.0393 0.6672
Mycobacterium ulcerans multifunctional mycocerosic acid synthase membrane-associated Mas 0.0055 0.0135 0.3289
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0052 0.0127 0.0127
Brugia malayi RE15519p 0.0039 0.0088 0.0106
Onchocerca volvulus 0.002 0.003 0.0121
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0035 0.0075 0.0304
Brugia malayi glutathione reductase 0.008 0.021 0.0256
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0039 0.0088 0.0087
Loa Loa (eye worm) hypothetical protein 0.0013 0.001 0.0011
Loa Loa (eye worm) hypothetical protein 0.0039 0.0088 0.0105
Loa Loa (eye worm) neuropeptide F receptor 0.0039 0.0088 0.0105
Loa Loa (eye worm) hypothetical protein 0.007 0.018 0.0218
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0132 0.0367 0.0367
Loa Loa (eye worm) hypothetical protein 0.0032 0.0067 0.0081
Giardia lamblia PHD finger protein 15 0.0033 0.0068 0.1449
Echinococcus granulosus rhodopsin orphan GPCR 0.0039 0.0088 0.0087
Schistosoma mansoni opsin-like receptor 0.0039 0.0088 0.0087
Echinococcus multilocularis rhodopsin orphan GPCR 0.0039 0.0088 0.0087
Echinococcus multilocularis beta LACTamase domain containing family member 0.014 0.0393 0.0392
Mycobacterium tuberculosis Probable hydrolase 0.014 0.0393 0.1445
Onchocerca volvulus 0.009 0.0241 0.0979
Loa Loa (eye worm) hypothetical protein 0.0039 0.0088 0.0105
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0039 0.0088 0.0087
Trypanosoma cruzi major cysteine proteinase, putative 0.006 0.015 0.3803
Schistosoma mansoni serine/threonine protein kinase 0.0133 0.0372 0.0371
Trypanosoma cruzi hypothetical protein, conserved 0.014 0.0393 1
Loa Loa (eye worm) jmjC domain-containing protein 0.0067 0.0173 0.021
Giardia lamblia NADH oxidase lateral transfer candidate 0.0028 0.0053 0.1028
Loa Loa (eye worm) hypothetical protein 0.0039 0.0088 0.0105
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0017 0.0022 0.0541
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0126 0.035 0.1422
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0026 0.0048 0.119
Schistosoma mansoni jumonji/arid domain-containing protein 0.0069 0.0179 0.0178
Echinococcus granulosus kinesin family 1 0.0128 0.0354 0.0354
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0039 0.0088 0.0087
Plasmodium vivax kinesin-5 0.0017 0.002 0.0484
Loa Loa (eye worm) hypothetical protein 0.014 0.0393 0.0478
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0039 0.0088 0.0087
Giardia lamblia Fructose-bisphosphate aldolase 0.0126 0.035 0.9387
Echinococcus multilocularis transportin 1 0.0017 0.0021 0.002
Schistosoma mansoni tyrosine kinase 0.0155 0.0438 0.0437
Mycobacterium tuberculosis Probable dehydrogenase 0.0182 0.0519 0.1918
Schistosoma mansoni jumonji/arid domain-containing protein 0.0069 0.0179 0.0178
Schistosoma mansoni zinc finger protein 0.0027 0.005 0.0049
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0032 0.0067 0.0274
Brugia malayi MH2 domain containing protein 0.1536 0.46 0.561
Loa Loa (eye worm) hypothetical protein 0.0011 0.0002 0.0001
Entamoeba histolytica cysteine protease, putative 0.001 0.0001 0.0011
Echinococcus granulosus JmjC domain containing protein 4 0.0017 0.0022 0.0021
Brugia malayi hypothetical protein 0.0039 0.0088 0.0106
Loa Loa (eye worm) jmjC domain-containing protein 0.0017 0.0022 0.0025
Brugia malayi latrophilin 2 splice variant baaae 0.0517 0.1529 0.1864
Brugia malayi Pre-SET motif family protein 0.0105 0.0285 0.0346
Plasmodium falciparum cysteine proteinase falcipain 2a 0.002 0.003 0.1211
Echinococcus granulosus tyrosine protein kinase Lyn 0.0013 0.0009 0.0008
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0126 0.035 0.9414
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0012 0.0005 0.0018
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0067 0.0272
Onchocerca volvulus 0.0826 0.246 1
Onchocerca volvulus Serine\/threonine kinase homolog 0.0133 0.0372 0.1512
Entamoeba histolytica kinesin, putative 0.0017 0.002 0.0522
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.003 0.0119
Echinococcus multilocularis lysine specific demethylase 5A 0.0065 0.0165 0.0165
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0039 0.0088 0.0087
Loa Loa (eye worm) hypothetical protein 0.0039 0.0088 0.0105
Schistosoma mansoni hypothetical protein 0.0039 0.0088 0.0087
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0028 0.0053 0.1338
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0182 0.0519 0.8912
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0028 0.0053 0.1338
Onchocerca volvulus 0.0039 0.0088 0.0356
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0014 0.0013 0.005
Echinococcus granulosus zinc finger protein 0.0037 0.0082 0.0082
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0076 0.0199 0.5053
Echinococcus granulosus jumonji domain containing protein 0.0045 0.0107 0.0106
Schistosoma mansoni methyltransferase-related 0.0016 0.0017 0.0016
Onchocerca volvulus 0.014 0.0393 0.1597
Leishmania major cathepsin L-like protease 0.002 0.003 0.0548
Schistosoma mansoni eyes absent homolog 0.0048 0.0115 0.0114
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0039 0.0088 0.0356
Echinococcus granulosus 7tm_1 domain containing protein 0.0039 0.0088 0.0087
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0014 0.0011 0.001
Echinococcus granulosus chromobox protein 1 0.0058 0.0144 0.0144
Schistosoma mansoni hypothetical protein 0.003 0.006 0.0059
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0182 0.0519 0.1918
Loa Loa (eye worm) hypothetical protein 0.0039 0.0088 0.0105
Schistosoma mansoni biogenic amine receptor 0.0039 0.0088 0.0087
Loa Loa (eye worm) hypothetical protein 0.0039 0.0088 0.0105
Loa Loa (eye worm) hypothetical protein 0.0039 0.0088 0.0105
Echinococcus granulosus sex peptide receptor 0.0039 0.0088 0.0087
Echinococcus granulosus GPCR family 2 0.0239 0.0691 0.0691
Mycobacterium tuberculosis Probable lipase LipD 0.014 0.0393 0.1445
Leishmania major hypothetical protein, conserved 0.014 0.0393 1
Brugia malayi Cathepsin L-like precursor 0.002 0.003 0.0036
Mycobacterium leprae Polyketide synthase Pks13 0.0077 0.0202 0.3292
Loa Loa (eye worm) flap endonuclease-1 0.0019 0.0028 0.0033
Onchocerca volvulus 0.0039 0.0088 0.0356
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0076 0.0199 0.5053
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0014 0.0013 0.005
Brugia malayi Cathepsin L-like precursor 0.002 0.003 0.0036
Loa Loa (eye worm) heterochromatin protein 1 0.0058 0.0144 0.0175
Echinococcus multilocularis neuropeptides capa receptor 0.0039 0.0088 0.0087
Schistosoma mansoni opsin-like receptor 0.0039 0.0088 0.0087
Schistosoma mansoni hypothetical protein 0.0011 0.0002 0.0001
Echinococcus multilocularis 3 oxoacyl (acyl carrier protein) synthase 0.0013 0.0009 0.0008
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0076 0.0199 0.5053
Loa Loa (eye worm) neuropeptide F receptor 0.0039 0.0088 0.0105
Schistosoma mansoni ferritin 0.0016 0.0017 0.0016
Brugia malayi photoreceptor-specific nuclear receptor 0.0014 0.0011 0.0012
Onchocerca volvulus 0.002 0.003 0.0121
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0039 0.0088 0.0087
Toxoplasma gondii HEAT repeat-containing protein 0.0017 0.0021 0.0492
Brugia malayi Heterochromatin protein 1 0.0058 0.0144 0.0175
Schistosoma mansoni tar DNA-binding protein 0.0132 0.0367 0.0366
Brugia malayi Bromodomain containing protein 0.0134 0.0373 0.0455
Mycobacterium ulcerans polyketide synthase MbtD 0.0016 0.0017 0.0229
Echinococcus multilocularis survival motor neuron protein 1 0.0147 0.0412 0.0412
Trichomonas vaginalis ferritin, putative 0.0016 0.0017 0.0067
Echinococcus multilocularis dnaJ subfamily B 0.0305 0.089 0.089
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0076 0.0199 0.5053
Toxoplasma gondii HEAT repeat-containing protein 0.0017 0.0021 0.0492
Schistosoma mansoni neuropeptide receptor 0.0039 0.0088 0.0087
Entamoeba histolytica cysteine proteinase 2 0.001 0.0001 0.0011
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0028 0.0053 0.1338
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0022 0.0036 0.0035
Schistosoma mansoni thyroid hormone receptor 0.0014 0.0011 0.001
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0203 0.058 0.2148
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0039 0.0088 0.0087
Plasmodium falciparum 3-oxoacyl-acyl-carrier protein synthase I/II 0.0013 0.0009 0.0337
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0076 0.0199 0.5053
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0132 0.0369 0.0368
Toxoplasma gondii cathepsin CPL 0.002 0.003 0.0716
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0076 0.0199 0.5053
Loa Loa (eye worm) hypothetical protein 0.0039 0.0088 0.0105
Onchocerca volvulus 0.0021 0.0034 0.0139
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0014 0.0011 0.001
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0028 0.0053 0.1155
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0039 0.0088 0.0087
Echinococcus multilocularis g protein coupled receptor 0.0039 0.0088 0.0087
Onchocerca volvulus Mothers against decapentaplegic homolog 0.0047 0.0111 0.045
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0014 0.0011 0.001
Loa Loa (eye worm) hypothetical protein 0.0025 0.0046 0.0055
Echinococcus granulosus transcription factor Dp 1 0.003 0.0061 0.006
Echinococcus granulosus histone acetyltransferase KAT2B 0.0029 0.0058 0.0058
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0014 0.0011 0.001
Schistosoma mansoni amine GPCR 0.0039 0.0088 0.0087
Trichomonas vaginalis CAMK family protein kinase 0.0133 0.0372 0.151
Loa Loa (eye worm) hypothetical protein 0.0039 0.0088 0.0105
Loa Loa (eye worm) TAR-binding protein 0.0132 0.0367 0.0446
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0013 0.001 0.0038
Schistosoma mansoni hypothetical protein 0.3327 1 1
Loa Loa (eye worm) hypothetical protein 0.0039 0.0088 0.0105
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0014 0.0011 0.001
Echinococcus multilocularis importin subunit beta 1 0.009 0.0241 0.0241
Plasmodium falciparum ataxin-2 like protein, putative 0.007 0.018 0.7434
Loa Loa (eye worm) jmjC domain-containing protein 0.0017 0.0022 0.0025
Echinococcus multilocularis importin 5 0.0017 0.0021 0.002
Brugia malayi acetyltransferase, GNAT family protein 0.009 0.0241 0.0293
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.0042 0.0095 0.2245
Plasmodium falciparum ataxin-2 like protein, putative 0.007 0.018 0.7434
Schistosoma mansoni hypothetical protein 0.0027 0.005 0.0049
Trypanosoma cruzi PAB1-binding protein , putative 0.007 0.018 0.4565
Onchocerca volvulus 0.0039 0.0088 0.0356
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.003 0.0119
Loa Loa (eye worm) hypothetical protein 0.0029 0.0057 0.0068
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0059 0.0146 0.3719
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0039 0.0088 0.0087
Trichomonas vaginalis CAMK family protein kinase 0.0133 0.0372 0.151
Plasmodium vivax vivapain-2 0.002 0.003 0.0744
Brugia malayi hypothetical protein 0.0039 0.0088 0.0106
Onchocerca volvulus 0.0114 0.0313 0.1273
Loa Loa (eye worm) hypothetical protein 0.0123 0.0341 0.0414
Loa Loa (eye worm) hypothetical protein 0.0039 0.0088 0.0105
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0126 0.035 0.1422
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0014 0.0012 0.0011
Mycobacterium ulcerans bacterioferritin BfrA 0.0016 0.0017 0.0216
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0029 0.0058 0.1443
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0039 0.0088 0.0105
Schistosoma mansoni neuropeptide receptor 0.0039 0.0088 0.0087
Entamoeba histolytica cysteine protease, putative 0.001 0.0001 0.0011
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0028 0.0053 0.1155
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0033 0.0068 0.0067
Loa Loa (eye worm) hypothetical protein 0.0039 0.0088 0.0105
Plasmodium falciparum cysteine proteinase falcipain 3 0.002 0.003 0.1211
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.0016 0.0017 0.0035
Echinococcus granulosus G protein coupled receptor 139 0.0039 0.0088 0.0087
Echinococcus multilocularis cathepsin l cysteine peptidase 0.002 0.003 0.0029
Toxoplasma gondii PHD-finger domain-containing protein 0.0033 0.0068 0.1695
Brugia malayi RNA recognition motif domain containing protein 0.0132 0.0367 0.0446
Mycobacterium ulcerans hypothetical protein 0.014 0.0393 1
Brugia malayi MH1 domain containing protein 0.0105 0.0285 0.0347
Onchocerca volvulus 0.002 0.003 0.0121
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0028 0.0053 0.1155
Echinococcus multilocularis cathepsin L cysteine protease 0.002 0.003 0.0029
Leishmania major hypothetical protein, conserved 0.0016 0.0017 0.0204
Echinococcus multilocularis jumonji domain containing protein 0.0045 0.0107 0.0106
Entamoeba histolytica Ran family GTPase 0.0059 0.0146 0.3934
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0012 0.0006 0.0213
Trypanosoma brucei hypothetical protein, conserved 0.014 0.0393 1
Echinococcus multilocularis mothers against decapentaplegic 5 0.0105 0.0285 0.0284
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0014 0.0011 0.001
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0029 0.0058 0.0234
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0052 0.0127 0.3231
Trypanosoma cruzi polo-like protein kinase, putative 0.0133 0.0372 0.9468
Trypanosoma cruzi hypothetical protein, conserved 0.014 0.0393 1
Echinococcus granulosus neuropeptide receptor A26 0.0039 0.0088 0.0087
Loa Loa (eye worm) beta-ketoacyl synthase domain-containing protein 0.0013 0.0009 0.0009
Mycobacterium tuberculosis Polyketide synthetase MbtC (polyketide synthase) 0.0018 0.0023 0.0058
Echinococcus granulosus snurportin 1 0.0963 0.2872 0.2871
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0039 0.0088 0.0087
Loa Loa (eye worm) hypothetical protein 0.0039 0.0088 0.0105
Echinococcus multilocularis smad 0.0105 0.0285 0.0284
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSC 0.0055 0.0135 0.2096
Loa Loa (eye worm) hypothetical protein 0.0039 0.0088 0.0105
Brugia malayi Flap endonuclease-1 0.0019 0.0028 0.0034
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0028 0.0053 0.0052
Loa Loa (eye worm) hypothetical protein 0.0039 0.0088 0.0105
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0017 0.0021 0.0021
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0014 0.0011 0.001
Loa Loa (eye worm) hypothetical protein 0.0014 0.0011 0.0012
Schistosoma mansoni hypothetical protein 0.0239 0.0691 0.0691
Echinococcus granulosus neuropeptide Y receptor 0.0039 0.0088 0.0087
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0028 0.0053 0.2178
Schistosoma mansoni neuropeptide receptor 0.0039 0.0088 0.0087
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0126 0.035 0.1422
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0062 0.0156 0.2459
Loa Loa (eye worm) hypothetical protein 0.0039 0.0088 0.0105
Mycobacterium ulcerans polyketide synthase Pks9 0.0034 0.0073 0.1664
Brugia malayi SET domain containing protein 0.0014 0.0011 0.0013
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0014 0.0011 0.0012
Echinococcus multilocularis allatostatin A receptor 0.0039 0.0088 0.0087
Echinococcus multilocularis serotonin receptor 0.0039 0.0088 0.0087
Echinococcus granulosus neuropeptide s receptor 0.0039 0.0088 0.0087
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.003 0.0119
Loa Loa (eye worm) hypothetical protein 0.014 0.0393 0.0478
Brugia malayi G-protein coupled receptor 0.0039 0.0088 0.0106
Mycobacterium tuberculosis Probable membrane bound polyketide synthase Pks6 0.0077 0.0202 0.0731
Loa Loa (eye worm) hypothetical protein 0.0017 0.0022 0.0025
Plasmodium vivax importin-beta 2, putative 0.009 0.0241 0.614
Loa Loa (eye worm) importin-beta domain-containing protein 0.0017 0.0021 0.0024
Brugia malayi Pre-SET motif family protein 0.0726 0.2158 0.2631
Trypanosoma brucei ISWI complex protein 0.0027 0.005 0.1257
Schistosoma mansoni hypothetical protein 0.0305 0.089 0.089
Plasmodium falciparum phd finger protein, putative 0.0033 0.0068 0.2801
Loa Loa (eye worm) hypothetical protein 0.0017 0.0022 0.0025
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0039 0.0088 0.0087
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0014 0.0011 0.0012
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0028 0.0053 0.1338
Brugia malayi beta-lactamase family protein 0.014 0.0393 0.0478
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0014 0.0011 0.0012
Brugia malayi jmjC domain containing protein 0.0132 0.0369 0.0449
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0126 0.035 0.1422
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0014 0.0011 0.0012
Schistosoma mansoni methyl-cpg binding protein mbd 0.003 0.0059 0.0059
Brugia malayi RNA binding protein 0.0132 0.0367 0.0446
Echinococcus granulosus FTZ F1 alpha 0.0014 0.0011 0.001
Schistosoma mansoni serine/threonine protein kinase 0.273 0.8199 0.8199
Echinococcus multilocularis G-protein coupled receptor, putative 0.0039 0.0088 0.0087
Trypanosoma cruzi polo-like protein kinase, putative 0.0133 0.0372 0.9468
Brugia malayi hypothetical protein 0.0045 0.0105 0.0128
Echinococcus multilocularis zinc finger protein 0.0037 0.0082 0.0082
Loa Loa (eye worm) hypothetical protein 0.0039 0.0088 0.0105
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0039 0.0088 0.0106
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.003 0.0119
Echinococcus multilocularis rhodopsin orphan GPCR 0.0039 0.0088 0.0087
Mycobacterium tuberculosis Hypothetical protein 0.0016 0.0017 0.0033
Loa Loa (eye worm) CXXC zinc finger family protein 0.0021 0.0034 0.004
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.003 0.0119
Brugia malayi jmjC domain containing protein 0.0069 0.0179 0.0218
Echinococcus granulosus chromobox protein 1 0.0058 0.0144 0.0144
Brugia malayi beta-lactamase 0.014 0.0393 0.0478
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0017 0.0065
Loa Loa (eye worm) hypothetical protein 0.0014 0.0011 0.0012
Echinococcus multilocularis rhodopsin orphan GPCR 0.0039 0.0088 0.0087
Echinococcus granulosus rhodopsin orphan GPCR 0.0039 0.0088 0.0087
Leishmania major cathepsin L-like protease 0.002 0.003 0.0548
Schistosoma mansoni cpg binding protein 0.0026 0.0048 0.0047
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0073 0.019 0.077
Brugia malayi Beta-ketoacyl synthase, N-terminal domain containing protein 0.0052 0.0125 0.0152
Mycobacterium tuberculosis Probable reductase 0.0182 0.0519 0.1918
Loa Loa (eye worm) hypothetical protein 0.0039 0.0088 0.0105
Echinococcus multilocularis neuropeptide receptor A26 0.0039 0.0088 0.0087
Loa Loa (eye worm) hypothetical protein 0.0039 0.0088 0.0105
Leishmania major cathepsin L-like protease 0.002 0.003 0.0548
Schistosoma mansoni steroid hormone receptor ad4bp 0.0014 0.0011 0.001
Mycobacterium leprae PROBABLE THIOESTERASE TESA 0.0043 0.0099 0.1463
Echinococcus multilocularis rhodopsin orphan GPCR 0.0039 0.0088 0.0087
Echinococcus granulosus methyl CpG binding domain protein 2 0.003 0.0059 0.0059
Mycobacterium ulcerans thioesterase TesA 0.0043 0.0099 0.2361
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0134 0.0374 0.0374
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0158 0.0445 0.0444
Loa Loa (eye worm) MH2 domain-containing protein 0.0047 0.0111 0.0134
Mycobacterium ulcerans polyketide synthase 0.0055 0.0135 0.3289
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0019 0.0028 0.0704
Onchocerca volvulus Fatty acid synthase homolog 0.0093 0.025 0.1018
Leishmania major cysteine peptidase A (CPA) 0.002 0.003 0.0548
Loa Loa (eye worm) hypothetical protein 0.0033 0.0068 0.0082
Entamoeba histolytica cysteine protease, putative 0.001 0.0001 0.0011
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.003 0.006 0.0072
Plasmodium falciparum JmjC domain-containing protein, putative 0.0017 0.0022 0.0881
Plasmodium falciparum glutathione reductase 0.008 0.021 0.8713
Schistosoma mansoni apoferritin-2 0.0016 0.0017 0.0016
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0014 0.0011 0.001
Schistosoma mansoni ran 0.0059 0.0146 0.0146
Loa Loa (eye worm) hypothetical protein 0.0039 0.0088 0.0105
Brugia malayi larval opioid receptor 0.0039 0.0088 0.0106
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0076 0.0199 0.5053
Brugia malayi Tyrosine-protein kinase abl-1 0.0096 0.0258 0.0313
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0073 0.019 0.077
Entamoeba histolytica cysteine proteinase, putative 0.002 0.003 0.0796
Schistosoma mansoni retinoic acid receptor RXR 0.0014 0.0011 0.001
Loa Loa (eye worm) hypothetical protein 0.0039 0.0088 0.0105
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0028 0.0053 0.1338
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0014 0.0011 0.001
Loa Loa (eye worm) hypothetical protein 0.0063 0.0159 0.0192
Echinococcus granulosus smad 0.0105 0.0285 0.0284
Mycobacterium tuberculosis Conserved protein 0.0016 0.0017 0.0033
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0126 0.035 0.1422
Entamoeba histolytica hypothetical protein 0.0132 0.0367 0.9872
Onchocerca volvulus 0.0039 0.0088 0.0356
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0126 0.035 0.1422
Brugia malayi neuropeptide F receptor 0.0039 0.0088 0.0106
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0055 0.0135 0.3289
Echinococcus granulosus neuropeptide receptor 0.0039 0.0088 0.0087
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0011 0.0002 0.003
Echinococcus granulosus rhodopsin orphan GPCR 0.0039 0.0088 0.0087
Mycobacterium tuberculosis Probable multifunctional mycocerosic acid synthase membrane-associated Mas 0.0055 0.0135 0.0478
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0039 0.0088 0.0087
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0014 0.0011 0.0012
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0052 0.0127 0.0127
Echinococcus granulosus biogenic amine 5HT receptor 0.0039 0.0088 0.0087
Echinococcus multilocularis cathepsin L cysteine protease 0.002 0.003 0.0029
Echinococcus multilocularis chromobox protein 1 0.0058 0.0144 0.0144
Entamoeba histolytica cysteine proteinase, putative 0.002 0.003 0.0796
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0014 0.0013 0.005
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0039 0.0088 0.0105
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0014 0.0011 0.001
Toxoplasma gondii 3-oxoacyl-acyl-carrier protein synthase I/II, putative 0.0013 0.0009 0.0177
Trypanosoma cruzi trypanothione reductase, putative 0.0028 0.0053 0.1338
Schistosoma mansoni ferritin 0.0016 0.0017 0.0016
Echinococcus granulosus neuropeptide receptor 0.0039 0.0088 0.0087
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0126 0.035 0.1422
Schistosoma mansoni kinase 0.0072 0.0185 0.0185
Schistosoma mansoni alpha-1 adrenergic receptor 0.0039 0.0088 0.0087
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0014 0.0011 0.001
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsE 0.0034 0.0073 0.1664
Echinococcus granulosus cpg binding protein 0.0026 0.0048 0.0047
Echinococcus multilocularis phd:f box containing protein 0.0017 0.0022 0.0021
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0019 0.0028 0.0508
Loa Loa (eye worm) hypothetical protein 0.0014 0.0011 0.0012
Toxoplasma gondii PHD-finger domain-containing protein 0.0033 0.0068 0.1695
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0039 0.0088 0.0106
Onchocerca volvulus 0.0039 0.0088 0.0356
Echinococcus granulosus g protein coupled receptor 0.0039 0.0088 0.0087
Schistosoma mansoni hypothetical protein 0.3327 1 1
Plasmodium vivax ataxin-2 like protein, putative 0.007 0.018 0.4565
Plasmodium vivax SET domain protein, putative 0.0105 0.0285 0.7242
Wolbachia endosymbiont of Brugia malayi bacterioferritin/cytochrome b1 0.0016 0.0017 0.1871
Mycobacterium tuberculosis Probable polyketide synthase Pks9 0.0029 0.0058 0.0189
Toxoplasma gondii LsmAD domain-containing protein 0.007 0.018 0.4548
Brugia malayi jmjC domain containing protein 0.0017 0.0022 0.0026
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0039 0.0088 0.0087
Echinococcus granulosus tumor protein p63 0.0988 0.2947 0.2947
Echinococcus multilocularis neuropeptides capa receptor 0.0039 0.0088 0.0087
Schistosoma mansoni kinesin eg-5 0.0017 0.002 0.0019
Onchocerca volvulus 0.0014 0.0011 0.0043
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0039 0.0088 0.0087
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0028 0.0053 0.1338
Schistosoma mansoni Smad4 0.0047 0.0111 0.011
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0076 0.0199 0.5053
Plasmodium vivax JmjC domain containing protein 0.0017 0.0022 0.0541
Schistosoma mansoni importin beta-1 0.009 0.0241 0.0241
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0897 0.2674 1
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0126 0.035 0.9414
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.002 0.0031 0.0037
Loa Loa (eye worm) steroid hormone receptor 0.0014 0.0011 0.0012
Plasmodium vivax SET domain containing protein 0.0011 0.0001 0.0019
Loa Loa (eye worm) hypothetical protein 0.014 0.0393 0.0478
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0017 0.0022 0.0021
Echinococcus granulosus alpha 1A adrenergic receptor 0.0039 0.0088 0.0087
Loa Loa (eye worm) hypothetical protein 0.0039 0.0088 0.0105
Brugia malayi ORL1-like opioid receptor 0.0039 0.0088 0.0106
Schistosoma mansoni amine GPCR 0.0039 0.0088 0.0087
Schistosoma mansoni cathepsin F (C01 family) 0.002 0.003 0.0029
Trichomonas vaginalis CAMK family protein kinase 0.007 0.018 0.073
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.002 0.0031 0.0037
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.001 0.0001 0.0001
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.002 0.003 0.0035
Echinococcus multilocularis thioredoxin glutathione reductase 0.008 0.0212 0.0212
Loa Loa (eye worm) hypothetical protein 0.002 0.003 0.0035
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0019 0.0028 0.0704
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0014 0.0011 0.001
Schistosoma mansoni amine GPCR 0.0039 0.0088 0.0087
Brugia malayi Dopamine receptor 0.0039 0.0088 0.0106
Mycobacterium ulcerans beta-lactamase 0.014 0.0393 1
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0826 0.246 0.3
Echinococcus granulosus mothers against decapentaplegic 6 0.0047 0.0111 0.011
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0017 0.0021 0.0024
Schistosoma mansoni ferritin light chain 0.0016 0.0017 0.0016
Onchocerca volvulus 0.002 0.003 0.0121
Brugia malayi map kinase activated protein kinase protein 2 0.273 0.8199 1
Echinococcus granulosus serotonin receptor 0.0039 0.0088 0.0087
Loa Loa (eye worm) CHromoDomain protein family member 0.0014 0.0012 0.0013
Plasmodium falciparum histone acetyltransferase GCN5 0.0023 0.0039 0.1613
Entamoeba histolytica HEAT repeat domain containing protein 0.0017 0.0021 0.056
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0134 0.0374 0.0374
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0203 0.058 1
Trichomonas vaginalis flap endonuclease-1, putative 0.0019 0.0028 0.0112
Trypanosoma cruzi cruzipain precursor, putative 0.0076 0.0199 0.5053
Mycobacterium tuberculosis Polyketide synthase Pks2 0.005 0.0121 0.0424
Trichomonas vaginalis CAMK family protein kinase 0.0133 0.0372 0.151
Brugia malayi Smad1 0.0105 0.0285 0.0347
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0014 0.0011 0.0012
Loa Loa (eye worm) hypothetical protein 0.009 0.0241 0.0293
Brugia malayi hypothetical protein 0.0132 0.0367 0.0447
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0014 0.0011 0.0012
Brugia malayi AF-10 protein 0.0011 0.0002 0.0001
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0039 0.0088 0.0087
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.002 0.003 0.0119
Brugia malayi Thioredoxin reductase 0.008 0.021 0.0256
Echinococcus multilocularis jumonji domain containing 1A 0.0017 0.0022 0.0021
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0028 0.0053 0.1155
Entamoeba histolytica cysteine protease, putative 0.001 0.0001 0.0011
Brugia malayi Serotonin receptor 0.0039 0.0088 0.0106
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0028 0.0053 0.1338
Loa Loa (eye worm) hypothetical protein 0.0134 0.0374 0.0455
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.003 0.0119
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSE 0.0034 0.0073 0.0987
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0039 0.0088 0.0106
Loa Loa (eye worm) hypothetical protein 0.0039 0.0088 0.0105
Onchocerca volvulus Cathepsin F homolog 0.002 0.003 0.0121
Loa Loa (eye worm) transcription factor SMAD2 0.1536 0.46 0.5609
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0133 0.0372 0.9457
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.014 0.0393 0.0392
Loa Loa (eye worm) hypothetical protein 0.0039 0.0088 0.0105
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSA 0.0052 0.0125 0.1924
Loa Loa (eye worm) kinesin-like protein KLP2 0.0017 0.002 0.0022
Schistosoma mansoni bromodomain containing protein 0.0011 0.0002 0.0001
Loa Loa (eye worm) hypothetical protein 0.0039 0.0088 0.0105
Schistosoma mansoni jumonji domain containing protein 0.011 0.0302 0.0302
Loa Loa (eye worm) nuclear factor I 0.0058 0.0144 0.0174
Echinococcus multilocularis fmrfamide receptor 0.0039 0.0088 0.0087
Echinococcus granulosus cathepsin l1 0.0013 0.001 0.0009
Brugia malayi kap beta 3 protein 0.0017 0.0021 0.0025
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0031 0.0064 0.0063
Echinococcus granulosus tm gpcr rhodopsin 0.0039 0.0088 0.0087
Echinococcus multilocularis serotonin receptor 0.0039 0.0088 0.0087
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0031 0.0064 0.0063
Schistosoma mansoni biogenic amine (5HT) receptor 0.0039 0.0088 0.0087
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0028 0.0053 0.017
Brugia malayi mothers against decapentaplegic homolog 3 0.0047 0.0111 0.0134
Schistosoma mansoni ran 0.0059 0.0146 0.0146
Mycobacterium leprae Probable multifunctional mycocerosic acid synthase membrane associated enzyme Mas 0.0055 0.0135 0.2096
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.273 0.8199 1
Trypanosoma cruzi ISWI complex protein 0.0027 0.005 0.1257
Trypanosoma cruzi cysteine peptidase, putative 0.0076 0.0199 0.5053
Brugia malayi Bromodomain containing protein 0.0039 0.0087 0.0105
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0028 0.0053 0.1155
Brugia malayi GnHR receptor homolog 0.0039 0.0088 0.0106
Entamoeba histolytica cysteine protease, putative 0.001 0.0001 0.0011
Brugia malayi hypothetical protein 0.0039 0.0088 0.0106
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.002 0.003 0.0119
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0012 0.0006 0.0022
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0039 0.0088 0.0087
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0757 0.2251 0.2744
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0039 0.0088 0.0087
Mycobacterium tuberculosis Probable thioesterase TesA 0.0043 0.0099 0.0344
Loa Loa (eye worm) thioredoxin reductase 0.008 0.021 0.0255
Loa Loa (eye worm) hypothetical protein 0.0078 0.0203 0.0247
Brugia malayi Nuclear hormone receptor-like 1 0.0014 0.0011 0.0012
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0126 0.035 0.1422
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.003 0.0119
Onchocerca volvulus 0.0039 0.0088 0.0356
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0039 0.0088 0.0087
Entamoeba histolytica cysteine protease, putative 0.001 0.0001 0.0011
Loa Loa (eye worm) hypothetical protein 0.0517 0.1529 0.1864
Treponema pallidum NADH oxidase 0.0028 0.0053 0.1082
Brugia malayi Melatonin receptor type 1A 0.0039 0.0088 0.0106
Schistosoma mansoni zinc finger protein 0.0037 0.0082 0.0082
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.003 0.0119
Trichomonas vaginalis mercuric reductase, putative 0.0028 0.0053 0.0213
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0028 0.0053 1
Loa Loa (eye worm) hypothetical protein 0.0147 0.0412 0.0502
Echinococcus multilocularis cysteine protease 0.002 0.003 0.0029
Echinococcus granulosus transportin 1 0.0017 0.0021 0.002
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.009 0.0241 0.0241
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0039 0.0088 0.0087
Mycobacterium ulcerans polyketide synthase 0.0052 0.0125 0.3037
Echinococcus multilocularis tyrosine protein kinase Abl 0.0064 0.0163 0.0163
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0014 0.0012 0.0011
Onchocerca volvulus 0.0039 0.0088 0.0356
Trypanosoma brucei importin beta-1 subunit, putative 0.009 0.0241 0.614
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0076 0.0199 0.5053
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0105 0.0285 0.0284
Mycobacterium tuberculosis Conserved protein 0.014 0.0393 0.1445
Onchocerca volvulus 0.0039 0.0088 0.0356
Echinococcus granulosus mothers against decapentaplegic 2 0.0047 0.0111 0.011
Echinococcus granulosus tm gpcr rhodopsin 0.0039 0.0088 0.0087
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0203 0.058 0.2148
Loa Loa (eye worm) latrophilin receptor protein 2 0.0239 0.0691 0.0842
Mycobacterium tuberculosis Probable polyketide synthase Pks15 0.0021 0.0033 0.0094
Schistosoma mansoni cpg binding protein 0.0021 0.0034 0.0034
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.014 0.0393 0.1445
Loa Loa (eye worm) hypothetical protein 0.0039 0.0088 0.0105
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0052 0.0125 0.0442
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.2923 0.878 0.878
Echinococcus granulosus lysine specific demethylase 6a 0.0017 0.0022 0.0021
Schistosoma mansoni cellular tumor antigen P53 0.0145 0.0405 0.0405
Loa Loa (eye worm) hypothetical protein 0.0039 0.0088 0.0105
Trypanosoma cruzi PAB1-binding protein , putative 0.007 0.018 0.4565
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.001 0.0001 0.0001
Plasmodium vivax transportin, putative 0.0017 0.0021 0.0521
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0132 0.0367 0.0367
Mycobacterium ulcerans thioesterase 0.0043 0.0099 0.2361
Schistosoma mansoni hypothetical protein 0.0036 0.0078 0.0077
Trypanosoma brucei trypanothione reductase 0.008 0.021 0.535
Echinococcus granulosus jumonji domain containing 1A 0.0017 0.0022 0.0021
Echinococcus granulosus GTP binding nuclear protein Ran 0.0059 0.0146 0.0146
Entamoeba histolytica acetyltransferase, GNAT family 0.0023 0.0039 0.1056
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0105 0.0285 0.7233
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0069 0.0179 0.4546
Mycobacterium tuberculosis Conserved protein 0.014 0.0393 0.1445
Trichomonas vaginalis D-aminoacylase, putative 0.014 0.0393 0.1595
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.014 0.0393 0.0478
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0014 0.0011 0.0012
Onchocerca volvulus 0.003 0.006 0.0243
Schistosoma mansoni histamine h1 receptor 0.0039 0.0088 0.0087
Schistosoma mansoni protein phosphatase 2C 0.0017 0.0022 0.0021
Echinococcus granulosus peptide allatostatin:somatostatin 0.0039 0.0088 0.0087
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0309 0.0901 0.09
Loa Loa (eye worm) RNA binding protein 0.0132 0.0367 0.0446
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0059 0.0146 0.0177
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0052 0.0127 0.3231
Trypanosoma cruzi ISWI complex protein 0.0027 0.005 0.1257
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0039 0.0088 0.0087
Brugia malayi PHD-finger family protein 0.0033 0.0068 0.0082
Echinococcus multilocularis chromobox protein 1 0.0058 0.0144 0.0144
Brugia malayi oxidoreductase, zinc-binding dehydrogenase family protein 0.0098 0.0265 0.0322
Loa Loa (eye worm) G-protein coupled receptor 0.0039 0.0088 0.0105
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0039 0.0088 0.0087
Echinococcus granulosus PHD finger protein rhinoceros 0.0033 0.0068 0.0067
Entamoeba histolytica hypothetical protein 0.0132 0.0367 0.9872
Brugia malayi TAR-binding protein 0.0132 0.0367 0.0446
Schistosoma mansoni cathepsin F (C01 family) 0.002 0.003 0.0029
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0014 0.0011 0.0012
Trichomonas vaginalis penicillin-binding protein, putative 0.014 0.0393 0.1595
Brugia malayi Calcitonin receptor-like protein seb-1 0.0757 0.2251 0.2744
Trichomonas vaginalis hypothetical protein 0.0017 0.0021 0.0083
Schistosoma mansoni jumonji domain containing protein 0.0017 0.0022 0.0021
Brugia malayi cathepsin L-like precursor 0.0013 0.001 0.0011
Onchocerca volvulus Cathepsin L homolog 0.002 0.003 0.0121
Echinococcus multilocularis neuropeptide FF receptor 2 0.0039 0.0088 0.0087
Echinococcus multilocularis PHD finger protein rhinoceros 0.0033 0.0068 0.0067
Echinococcus multilocularis thyroid hormone receptor alpha 0.0014 0.0011 0.001
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0019 0.0028 0.0676
Echinococcus granulosus 3 oxoacyl acyl carrier protein synthase 0.0013 0.0009 0.0008
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0052 0.0127 0.3231
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0133 0.0372 0.0452
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0017 0.0021 0.0021
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0028 0.0053 1
Echinococcus multilocularis Smad4 0.0105 0.0285 0.0284
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.008 0.021 0.0761
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0017 0.0021 0.0021
Loa Loa (eye worm) bromodomain containing protein 0.0033 0.0069 0.0082
Echinococcus granulosus survival motor neuron protein 1 0.0147 0.0412 0.0412
Loa Loa (eye worm) hypothetical protein 0.006 0.015 0.0181
Onchocerca volvulus 0.0039 0.0088 0.0356
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0052 0.0125 0.3037
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.0052 0.0125 0.0442
Brugia malayi Cathepsin L-like precursor 0.0013 0.001 0.0011
Leishmania major hypothetical protein, conserved 0.007 0.018 0.445
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.003 0.0119
Leishmania major cathepsin L-like protease 0.002 0.003 0.0548
Loa Loa (eye worm) hypothetical protein 0.0039 0.0088 0.0105
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0059 0.0146 0.0178
Loa Loa (eye worm) hypothetical protein 0.0039 0.0088 0.0105
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0014 0.0013 0.005
Echinococcus granulosus expressed protein 0.0016 0.0017 0.0016
Mycobacterium ulcerans lipase LipD 0.014 0.0393 1
Echinococcus granulosus translational activator gcn1 0.0017 0.0021 0.002
Echinococcus granulosus peregrin 0.0039 0.0087 0.0086
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0014 0.0011 0.0012
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0014 0.0011 0.001
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0039 0.0088 0.0087
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0014 0.0011 0.0012
Echinococcus granulosus g protein coupled receptor 0.0039 0.0088 0.0087
Brugia malayi hypothetical protein 0.0039 0.0088 0.0106
Loa Loa (eye worm) Smad1 0.0105 0.0285 0.0346
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0014 0.0011 0.0012
Loa Loa (eye worm) hypothetical protein 0.0145 0.0405 0.0493
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0011 0.0002 0.003
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0059 0.0146 0.3655
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0067 0.0272
Brugia malayi Cathepsin L-like precursor 0.0013 0.001 0.0011
Onchocerca volvulus 0.0039 0.0088 0.0356
Trichomonas vaginalis set domain proteins, putative 0.0826 0.246 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0014 0.0013 0.005
Schistosoma mansoni methyl-cpg binding protein mbd 0.003 0.0059 0.0059
Brugia malayi G-protein coupled receptor 0.0039 0.0088 0.0106
Mycobacterium tuberculosis Probable polyketide synthase Pks1 0.0037 0.0082 0.0277
Schistosoma mansoni 3-oxoacyl-[ACP] synthase 0.0013 0.0009 0.0008
Leishmania major cathepsin L-like protease 0.0076 0.0199 0.4949
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0028 0.0053 0.1338
Echinococcus granulosus orexin receptor type 2 0.0039 0.0088 0.0087
Echinococcus granulosus 7TM GPCR rhodopsin 0.0039 0.0088 0.0087
Brugia malayi beta-lactamase family protein 0.014 0.0393 0.0478
Mycobacterium tuberculosis Bacterioferritin BfrB 0.0016 0.0017 0.0035
Schistosoma mansoni apoferritin-2 0.0016 0.0017 0.0016
Giardia lamblia Kinesin-5 0.0017 0.002 0.0086
Loa Loa (eye worm) melatonin receptor type 1A 0.0039 0.0088 0.0105
Brugia malayi G protein-coupled receptor F59B2.13 0.0039 0.0088 0.0106
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0039 0.0088 0.0087
Echinococcus multilocularis expressed protein 0.0016 0.0017 0.0016
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.003 0.0119
Entamoeba histolytica cysteine proteinase, putative 0.0013 0.001 0.0261
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0636 0.1888 0.1887
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0014 0.0011 0.0012
Echinococcus granulosus Smad4 0.0105 0.0285 0.0284
Onchocerca volvulus 0.002 0.003 0.0121
Echinococcus granulosus tachykinin peptides receptor 99D 0.0039 0.0088 0.0087
Echinococcus multilocularis methyl CpG binding domain protein 2 0.003 0.0059 0.0059
Echinococcus granulosus biogenic amine 5HT receptor 0.0636 0.1888 0.1887
Brugia malayi MH2 domain containing protein 0.0105 0.0285 0.0347
Mycobacterium tuberculosis Polyketide synthase Pks13 0.0077 0.0202 0.0731
Loa Loa (eye worm) hypothetical protein 0.0039 0.0088 0.0105
Brugia malayi Dopamine receptor protein 1 0.0039 0.0088 0.0106
Schistosoma mansoni tar DNA-binding protein 0.0132 0.0367 0.0366
Trichomonas vaginalis CAMK family protein kinase 0.0133 0.0372 0.151
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0039 0.0088 0.0087
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0039 0.0088 0.0087
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0052 0.0127 0.0127
Entamoeba histolytica cysteine protease, putative 0.001 0.0001 0.0011
Echinococcus granulosus ecdysone induced protein 78C 0.0014 0.0011 0.001
Schistosoma mansoni Smad4 0.0105 0.0285 0.0284
Loa Loa (eye worm) hypothetical protein 0.0014 0.0011 0.0012
Loa Loa (eye worm) glutathione reductase 0.008 0.021 0.0255
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0107 0.0293 0.0292
Trypanosoma cruzi trypanothione reductase, putative 0.008 0.021 0.535
Trichomonas vaginalis chromobox protein, putative 0.0035 0.0075 0.0302
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0014 0.0012 0.0011
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0049 0.0118 0.0118
Brugia malayi CXXC zinc finger family protein 0.0021 0.0034 0.0041
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0048 0.0115 0.0403
Trypanosoma brucei importin beta-1 subunit, putative 0.009 0.0241 0.614
Schistosoma mansoni hypothetical protein 0.0031 0.0064 0.0063
Trichomonas vaginalis chromobox protein, putative 0.0035 0.0075 0.0302
Loa Loa (eye worm) hypothetical protein 0.0039 0.0088 0.0105
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0039 0.0088 0.0106
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0134 0.0374 0.0374
Schistosoma mansoni smad 0.0105 0.0285 0.0284
Loa Loa (eye worm) hypothetical protein 0.0039 0.0088 0.0105
Loa Loa (eye worm) hypothetical protein 0.0239 0.0691 0.0842
Entamoeba histolytica cysteine protease, putative 0.001 0.0001 0.0011
Schistosoma mansoni biogenic amine receptor 0.0039 0.0088 0.0087
Loa Loa (eye worm) hypothetical protein 0.0826 0.246 0.2999
Echinococcus multilocularis neuropeptide Y receptor 0.0039 0.0088 0.0087
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0239 0.0691 0.0691
Schistosoma mansoni ferritin light chain 0.0016 0.0017 0.0016
Trichomonas vaginalis CAMK family protein kinase 0.0133 0.0372 0.151
Mycobacterium tuberculosis Conserved protein 0.014 0.0393 0.1445
Loa Loa (eye worm) hypothetical protein 0.0013 0.001 0.0011
Entamoeba histolytica serine/threonine protein kinase, putative 0.0133 0.0372 1
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0105 0.0285 0.0284
Onchocerca volvulus Bile acid receptor homolog 0.0014 0.0011 0.0043
Onchocerca volvulus 0.0039 0.0088 0.0356
Brugia malayi jmjC domain containing protein 0.0017 0.0022 0.0026
Echinococcus granulosus neuropeptide FF receptor 2 0.0039 0.0088 0.0087
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0107 0.0293 0.0292
Echinococcus granulosus hypothetical protein 0.0039 0.0088 0.0087
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0114 0.0313 0.0313
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0963 0.2872 0.3502
Trichomonas vaginalis CAMK family protein kinase 0.0133 0.0372 0.151
Brugia malayi ecdysteroid receptor 0.0014 0.0011 0.0012
Brugia malayi hypothetical protein 0.0039 0.0088 0.0106
Echinococcus granulosus histone acetyltransferase KAT2B 0.0084 0.0221 0.0221
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0014 0.0011 0.0012
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0014 0.0011 0.001
Trypanosoma brucei ULK family serine/threonine-protein kinase, putative 0.0025 0.0045 0.1127
Schistosoma mansoni hypothetical protein 0.0239 0.0691 0.0691
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0133 0.0372 0.0371
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0028 0.0053 0.1338
Echinococcus multilocularis cysteine protease 0.002 0.003 0.0029
Schistosoma mansoni tar DNA-binding protein 0.0132 0.0367 0.0366
Echinococcus granulosus neuropeptides capa receptor 0.0039 0.0088 0.0087
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.014 0.0393 0.1445
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0028 0.0053 0.1338
Schistosoma mansoni bromodomain containing protein 0.0114 0.0312 0.0311
Brugia malayi Serotonin receptor 0.0039 0.0088 0.0106
Schistosoma mansoni hypothetical protein 0.0517 0.1529 0.1528
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0017 0.0022 0.0512
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0239 0.0691 0.0691
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0014 0.0011 0.001
Loa Loa (eye worm) hypothetical protein 0.0087 0.0231 0.0281
Plasmodium falciparum flap endonuclease 1 0.0019 0.0028 0.1147
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0052 0.0127 0.0155
Echinococcus multilocularis geminin 0.3327 1 1
Plasmodium falciparum cysteine proteinase falcipain 2b 0.002 0.003 0.1211
Trichomonas vaginalis chromobox protein, putative 0.0058 0.0144 0.0584
Loa Loa (eye worm) hypothetical protein 0.0039 0.0088 0.0105
Loa Loa (eye worm) acyl carrier protein 0.0024 0.0041 0.0049
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0182 0.0519 0.1918
Entamoeba histolytica cysteine proteinase, putative 0.001 0.0001 0.0011
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0014 0.0011 0.0012
Trypanosoma cruzi cysteine peptidase, putative 0.0076 0.0199 0.5053
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0133 0.0372 0.0371
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0076 0.0199 0.5053
Loa Loa (eye worm) hypothetical protein 0.0039 0.0088 0.0105
Mycobacterium tuberculosis Probable polyketide synthase Pks5 0.005 0.0121 0.0424
Entamoeba histolytica cysteine proteinase 1, putative 0.001 0.0001 0.0011
Loa Loa (eye worm) MH1 domain-containing protein 0.0047 0.0111 0.0134
Loa Loa (eye worm) PHD-finger family protein 0.0036 0.0078 0.0094
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0059 0.0146 0.3719
Loa Loa (eye worm) hypothetical protein 0.0014 0.0011 0.0012
Entamoeba histolytica hypothetical protein 0.0132 0.0367 0.9872
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0062 0.0156 0.3822
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0014 0.0013 0.005
Brugia malayi AKH receptor 0.0039 0.0088 0.0106
Mycobacterium tuberculosis Probable polyketide synthase Pks8 0.0042 0.0097 0.0335
Echinococcus granulosus ferritin 0.0016 0.0017 0.0016
Trichomonas vaginalis esterase, putative 0.014 0.0393 0.1595
Brugia malayi G protein-coupled receptor 0.0039 0.0088 0.0106
Schistosoma mansoni smad1 5 8 and 0.0105 0.0285 0.0284
Toxoplasma gondii histone lysine methyltransferase SET1 0.0051 0.0122 0.3084
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0039 0.0156
Mycobacterium ulcerans bacterioferritin BfrB 0.0016 0.0017 0.0216
Leishmania major hypothetical protein, conserved 0.0027 0.005 0.1073
Loa Loa (eye worm) hypothetical protein 0.0039 0.0088 0.0105
Echinococcus granulosus dro:myosuppressin receptor 0.0039 0.0088 0.0087
Plasmodium vivax vivapain-2 0.002 0.003 0.0744
Leishmania major cathepsin L-like protease 0.0076 0.0199 0.4949
Brugia malayi chromobox protein homolog 3 0.0032 0.0067 0.0082
Mycobacterium tuberculosis Probable lipase LipE 0.014 0.0393 0.1445
Echinococcus multilocularis flap endonuclease 1 0.0019 0.0028 0.0028
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0182 0.0519 0.1918
Schistosoma mansoni nuclear hormone receptor 0.0014 0.0011 0.001
Brugia malayi putative neuropeptide receptor 0.0039 0.0088 0.0106
Echinococcus granulosus beta LACTamase domain containing family member 0.014 0.0393 0.0392
Leishmania major cathepsin L-like protease 0.0076 0.0199 0.4949
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.003 0.0119
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0014 0.0011 0.0012
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.003 0.0119
Brugia malayi Cathepsin L-like cysteine proteinase 0.0013 0.001 0.0011
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.273 0.8199 0.8199
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0063 0.0158 0.0158
Trypanosoma cruzi importin beta-1 subunit, putative 0.0073 0.019 0.483
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.003 0.0119
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0132 0.0369 0.0368
Mycobacterium tuberculosis Probable esterase LipL 0.014 0.0393 0.1445
Schistosoma mansoni chromobox protein 0.0058 0.0144 0.0144
Loa Loa (eye worm) hypothetical protein 0.0058 0.0144 0.0174
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0048 0.0115 0.0139
Loa Loa (eye worm) hypothetical protein 0.0039 0.0088 0.0105
Leishmania major cathepsin L-like protease 0.002 0.003 0.0548
Echinococcus multilocularis fetal alzheimer antigen, falz 0.004 0.0092 0.0091
Schistosoma mansoni hypothetical protein 0.0963 0.2872 0.2871
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0039 0.0088 0.0087
Brugia malayi Beta-ketoacyl synthase, N-terminal domain containing protein 0.0013 0.0009 0.001
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0014 0.0011 0.001
Schistosoma mansoni hypothetical protein 0.0039 0.0088 0.0087
Schistosoma mansoni hypothetical protein 0.0132 0.0367 0.0367
Entamoeba histolytica hypothetical protein 0.0132 0.0367 0.9872
Schistosoma mansoni adenoreceptor 0.0039 0.0088 0.0087
Echinococcus granulosus microtubule associated protein 2 0.1528 0.4576 0.4576
Loa Loa (eye worm) jmjC domain-containing protein 0.0069 0.0179 0.0217
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0017 0.0021 0.0021
Entamoeba histolytica cysteine proteinase, putative 0.001 0.0001 0.0011
Loa Loa (eye worm) PHD-finger family protein 0.0033 0.0068 0.0082
Loa Loa (eye worm) hypothetical protein 0.0067 0.0171 0.0207
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.004 0.0092 0.0091
Brugia malayi nuclear receptor NHR-88 0.0014 0.0011 0.0012
Echinococcus multilocularis neuropeptide receptor 0.0039 0.0088 0.0087
Brugia malayi putative neuropeptide receptor NPR1 0.0039 0.0088 0.0106
Echinococcus multilocularis ferritin 0.0016 0.0017 0.0016
Echinococcus multilocularis tar DNA binding protein 0.0132 0.0367 0.0366
Trichomonas vaginalis chromobox protein, putative 0.0058 0.0144 0.0584
Plasmodium vivax hypothetical protein, conserved 0.0012 0.0006 0.0131
Plasmodium falciparum kinesin-5 0.0017 0.002 0.0788
Trypanosoma cruzi beta-ketoacyl synthase family protein, putative 0.0013 0.0009 0.0207
Schistosoma mansoni mixed-lineage leukemia protein mll 0.002 0.0029 0.0029
Mycobacterium ulcerans polyketide synthase Pks13 0.0077 0.0202 0.5043
Toxoplasma gondii NADPH-glutathione reductase 0.0028 0.0053 0.1311
Brugia malayi steroid hormone receptor 0.0014 0.0011 0.0012
Leishmania major trypanothione reductase 0.008 0.021 0.5252
Onchocerca volvulus 0.0145 0.0405 0.1648
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.003 0.0119
Toxoplasma gondii beta-ketoacyl synthase, N-terminal domain-containing protein 0.0034 0.0071 0.1761
Entamoeba histolytica cysteine protease, putative 0.001 0.0001 0.0011
Trypanosoma cruzi beta-ketoacyl synthase family protein, putative 0.0013 0.0009 0.0207
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0014 0.0011 0.0012
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0039 0.0088 0.0087
Entamoeba histolytica cysteine proteinase, putative 0.001 0.0001 0.0011
Schistosoma mansoni growth hormone secretagogue receptor 0.0039 0.0088 0.0087
Brugia malayi jmjC domain containing protein 0.0017 0.0022 0.0026
Toxoplasma gondii HEAT repeat-containing protein 0.009 0.0241 0.6129
Brugia malayi Steroid receptor seven-up type 2 0.0014 0.0011 0.0012
Echinococcus multilocularis G protein coupled receptor 139 0.0039 0.0088 0.0087
Plasmodium falciparum glutathione reductase 0.0028 0.0053 0.2178
Mycobacterium leprae Probable lipase LipE 0.014 0.0393 0.6672
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0022 0.0036 0.0035
Loa Loa (eye worm) fatty acid synthase 0.0051 0.0123 0.0149
Onchocerca volvulus 0.0039 0.0088 0.0356
Onchocerca volvulus 0.014 0.0393 0.1597
Brugia malayi MH1 domain containing protein 0.0105 0.0285 0.0347
Entamoeba histolytica cysteine protease, putative 0.001 0.0001 0.0011
Schistosoma mansoni neuropeptide f receptor 76f 0.0039 0.0088 0.0087
Echinococcus multilocularis rhodopsin orphan GPCR 0.0039 0.0088 0.0087
Schistosoma mansoni importin-beta 2 0.0017 0.0021 0.002
Brugia malayi RNA, U transporter 1 0.0256 0.0743 0.0905
Schistosoma mansoni smad1 5 8 and 0.0105 0.0285 0.0284
Trichomonas vaginalis D-aminoacylase, putative 0.014 0.0393 0.1595
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.003 0.0119
Entamoeba histolytica Flap nuclease, putative 0.0019 0.0028 0.0754
Trypanosoma brucei PAB1-binding protein , putative 0.007 0.018 0.4565
Onchocerca volvulus 0.0013 0.001 0.004
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0017 0.0021 0.0025
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0039 0.0088 0.0087
Loa Loa (eye worm) hypothetical protein 0.014 0.0393 0.0478
Echinococcus granulosus cathepsin L cysteine proteinase 0.002 0.003 0.0029
Mycobacterium ulcerans Type I modular polyketide synthase 0.0052 0.0125 0.3037
Onchocerca volvulus Alhambra homolog 0.0033 0.0068 0.0277
Schistosoma mansoni smad 0.0047 0.0111 0.011
Echinococcus multilocularis fmrfamide receptor 0.0039 0.0088 0.0087
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0039 0.0088 0.0087
Loa Loa (eye worm) jmjC domain-containing protein 0.0017 0.0022 0.0025
Echinococcus multilocularis GPCR, family 2 0.0239 0.0691 0.0691
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0028 0.0053 0.1338
Echinococcus granulosus allatostatin A receptor 0.0039 0.0088 0.0087
Brugia malayi MH2 domain containing protein 0.0047 0.0111 0.0134
Echinococcus multilocularis transcription factor Dp 1 0.003 0.0061 0.006
Loa Loa (eye worm) hypothetical protein 0.0039 0.0088 0.0105
Schistosoma mansoni cathepsin F (C01 family) 0.0013 0.001 0.0009
Trypanosoma brucei Importin-beta N-terminal domain/HEAT-like repeat, putative 0.0017 0.0021 0.0521
Toxoplasma gondii type I fatty acid synthase, putative 0.0037 0.008 0.2013
Brugia malayi MH1 domain containing protein 0.0058 0.0144 0.0175
Schistosoma mansoni phd/f-box containing protein 0.0017 0.0022 0.0021
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0014 0.0011 0.0043
Leishmania major GTP-binding protein, putative 0.0059 0.0146 0.3586
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.003 0.0119
Echinococcus granulosus rhodopsin orphan GPCR 0.0039 0.0088 0.0087
Onchocerca volvulus 0.041 0.1204 0.4895
Loa Loa (eye worm) hypothetical protein 0.0047 0.0111 0.0134
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0105 0.0285 0.0284
Trichomonas vaginalis importin beta-1, putative 0.0073 0.019 0.077
Brugia malayi PHD-finger family protein 0.0015 0.0015 0.0018
Plasmodium vivax hypothetical protein, conserved 0.014 0.0393 1
Brugia malayi sulfakinin receptor protein 0.0039 0.0088 0.0106
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0039 0.0088 0.0087
Mycobacterium tuberculosis Polyketide synthetase MbtD (polyketide synthase) 0.0016 0.0017 0.0037
Entamoeba histolytica cysteine protease, putative 0.002 0.003 0.0796
Brugia malayi hypothetical protein 0.0048 0.0115 0.0139
Mycobacterium tuberculosis Polyketide synthase Pks12 0.0055 0.0135 0.0478
Schistosoma mansoni cpg binding protein 0.0026 0.0048 0.0047
Loa Loa (eye worm) hypothetical protein 0.0039 0.0088 0.0105

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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