Detailed information for compound 407986

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 1576.75 | Formula: C77H105N15O21
  • H donors: 19 H acceptors: 22 LogP: 4.03 Rotable bonds: 59
    Rule of 5 violations (Lipinski): 4
  • SMILES: CC[C@@H]([C@@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)O)Cc1c[nH]c2c1cccc2)[C@H](CC)C)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](C(C)C)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)CCC(=O)O)CCC(=O)O)C)Cc1ccc(cc1)O)Cc1ccccc1)C)Cc1nc[nH]c1)CC(C)C)CC(=O)O)C
  • InChi: 1S/C77H105N15O21/c1-11-41(7)64(75(110)89-58(77(112)113)33-47-36-79-51-21-17-16-20-50(47)51)92-76(111)65(42(8)12-2)91-73(108)57(35-62(99)100)87-70(105)53(30-39(3)4)85-72(107)56(34-48-37-78-38-80-48)84-66(101)43(9)82-69(104)54(31-45-18-14-13-15-19-45)86-71(106)55(32-46-22-24-49(93)25-23-46)88-74(109)63(40(5)6)90-67(102)44(10)81-68(103)52(26-28-60(95)96)83-59(94)27-29-61(97)98/h13-25,36-44,52-58,63-65,79,93H,11-12,26-35H2,1-10H3,(H,78,80)(H,81,103)(H,82,104)(H,83,94)(H,84,101)(H,85,107)(H,86,106)(H,87,105)(H,88,109)(H,89,110)(H,90,102)(H,91,108)(H,92,111)(H,95,96)(H,97,98)(H,99,100)(H,112,113)/t41-,42-,43-,44-,52-,53-,54-,55-,56-,57-,58-,63-,64-,65-/m0/s1
  • InChiKey: PXCMGJMNTZLMFD-MKVQGMSTSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Sus scrofa Endothelin receptor ET-B Starlite/ChEMBL No references
Sus scrofa Endothelin receptor ET-A Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Schistosoma japonicum ko:K04135 adrenergic receptor, alpha 1a, putative Endothelin receptor ET-B   443 aa 392 aa 23.5 %
Onchocerca volvulus Endothelin receptor ET-B   443 aa 371 aa 20.5 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi hypothetical protein 0.0019 0.0019 0.0036
Echinococcus multilocularis muscleblind protein 1 0.0159 0.0347 0.0439
Loa Loa (eye worm) hypothetical protein 0.0019 0.0019 0.0035
Echinococcus granulosus dnaJ subfamily B 0.0289 0.0653 0.1239
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0141 0.0304 0.2836
Echinococcus multilocularis somatostatin receptor 0.0958 0.2226 0.2812
Echinococcus granulosus g-protein coupled receptor 0.0958 0.2226 0.4225
Trypanosoma cruzi hypothetical protein, conserved 0.0017 0.0014 0.0448
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0119 0.0253 0.1078
Brugia malayi hypothetical protein 0.0019 0.0019 0.0035
Trypanosoma brucei DNA damage repair protein, putative 0.0018 0.0016 0.0519
Loa Loa (eye worm) DR-78 0.0019 0.0019 0.0036
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0012 0.0001 0.0002
Mycobacterium ulcerans secreted Mpt51/Mpb51 antigen protein FbpD 0.0035 0.0055 0.0231
Mycobacterium tuberculosis Conserved hypothetical membrane protein 0.0035 0.0055 0.0234
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0016 0.0011 0.043
Brugia malayi hypothetical protein 0.005 0.0091 0.0172
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0012 0.0002 0.0003
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0019 0.0019 0.0168
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0019 0.0019 0.0036
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.006
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0057 0.0057
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0095 0.0198 0.0375
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0141 0.0304 0.2836
Brugia malayi Dopamine receptor protein 2 0.0958 0.2226 0.4225
Loa Loa (eye worm) patched family protein 0.0025 0.0031 0.006
Echinococcus granulosus glutamate receptor 2 0.0012 0.0002 0.0003
Loa Loa (eye worm) hypothetical protein 0.1408 0.3283 0.6231
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0017 0.0012 0.0405
Brugia malayi Muscleblind-like protein 0.0159 0.0347 0.0659
Brugia malayi MH2 domain containing protein 0.0116 0.0246 0.0466
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.006
Mycobacterium leprae SECRETED ANTIGEN 85-C FBPC (85C) (ANTIGEN 85 COMPLEX C) (AG58C) (MYCOLYL TRANSFERASE 85C) (FIBRONECTIN-BINDING PROTEIN C) 0.0821 0.1903 0.8091
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0135 0.0291 0.0291
Onchocerca volvulus 0.0057 0.0107 0.0324
Schistosoma mansoni lipoxygenase 0.0039 0.0065 0.0065
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0041 0.007 0.0088
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.006
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0141 0.0304 1
Echinococcus multilocularis glutamate receptor 2 0.0012 0.0002 0.0002
Leishmania major glycosyl hydrolase-like protein 0.0013 0.0005 0.0155
Loa Loa (eye worm) hypothetical protein 0.0958 0.2226 0.4225
Plasmodium falciparum JmjC domain-containing protein, putative 0.0017 0.0012 0.0792
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0019 0.0168
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0038 0.0062 0.3104
Echinococcus granulosus dna polymerase kappa 0.0059 0.0111 0.021
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0038 0.0062 0.0078
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0141 0.0304 0.2836
Loa Loa (eye worm) hypothetical protein 0.0074 0.0146 0.0277
Loa Loa (eye worm) hypothetical protein 0.0013 0.0005 0.0009
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.0198 0.1843
Trypanosoma brucei DNA polymerase kappa, putative 0.0059 0.0111 0.3649
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0017 0.0014 0.0448
Loa Loa (eye worm) hypothetical protein 0.0958 0.2226 0.4225
Trypanosoma cruzi DNA damage repair protein, putative 0.0018 0.0016 0.0519
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0141 0.0304 0.2836
Echinococcus multilocularis bloom syndrome protein 0.0025 0.0032 0.0041
Leishmania major hypothetical protein, conserved 0.0077 0.0155 0.5111
Schistosoma mansoni lamin 0.0057 0.0107 0.0107
Toxoplasma gondii hypothetical protein 0.0025 0.0031 0.1196
Brugia malayi Animal haem peroxidase family protein 0.1408 0.3283 0.6231
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.0011 0.0372
Brugia malayi Nuclear hormone receptor E75 0.0019 0.0019 0.0036
Loa Loa (eye worm) hypothetical protein 0.0055 0.0102 0.0194
Echinococcus granulosus ecdysone induced protein 78C 0.0041 0.007 0.0133
Echinococcus granulosus intermediate filament protein 0.0057 0.0107 0.0203
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0016 0.0011 0.0048
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0958 0.2226 0.4225
Onchocerca volvulus Huntingtin homolog 0.0121 0.0258 0.0786
Echinococcus multilocularis rhodopsin orphan GPCR 0.0958 0.2226 0.2812
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0022 0.0024 0.0101
Brugia malayi Serotonin receptor 0.0958 0.2226 0.4225
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0017 0.0014 0.0014
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0074 0.0146 0.0619
Brugia malayi Patched family protein 0.0025 0.0031 0.006
Mycobacterium tuberculosis Probable DNA polymerase III (alpha chain) DnaE1 (DNA nucleotidyltransferase) 0.1012 0.2352 1
Echinococcus multilocularis peroxidasin 0.1408 0.3283 0.4148
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0017 0.0014 0.0026
Trypanosoma brucei unspecified product 0.0059 0.0111 0.3649
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0016 0.0011 0.0046
Trichomonas vaginalis ap endonuclease, putative 0.0038 0.0062 0.0572
Leishmania major importin beta-1 subunit, putative 0.0025 0.0032 0.104
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0041 0.007 0.0133
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0022 0.0024 0.0099
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0019 0.0019
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0022 0.0024 0.0099
Brugia malayi DOMON domain containing protein 0.0431 0.0987 0.1873
Brugia malayi beta-lactamase family protein 0.0036 0.0057 0.0108
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0958 0.2226 0.2812
Onchocerca volvulus Dual oxidase homolog 0.1408 0.3283 1
Echinococcus multilocularis lysine specific demethylase 6a 0.0017 0.0012 0.0016
Loa Loa (eye worm) hypothetical protein 0.0176 0.0387 0.0734
Echinococcus granulosus dna polymerase eta 0.0085 0.0174 0.033
Treponema pallidum DNA polymerase III subunit alpha 0.1012 0.2352 1
Schistosoma mansoni hypothetical protein 0.017 0.0372 0.0372
Loa Loa (eye worm) hypothetical protein 0.0958 0.2226 0.4225
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0068 0.224
Echinococcus granulosus neutral alpha glucosidase AB 0.0036 0.0058 0.011
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0057 0.1874
Loa Loa (eye worm) PDE1B protein 0.0017 0.0014 0.0026
Echinococcus granulosus alpha 1A adrenergic receptor 0.0958 0.2226 0.4225
Loa Loa (eye worm) hypothetical protein 0.0045 0.0078 0.0149
Loa Loa (eye worm) hypothetical protein 0.0958 0.2226 0.4225
Echinococcus granulosus nuclear receptor nhr 48 0.0019 0.0019 0.0036
Loa Loa (eye worm) RGS-3 protein 0.0019 0.0019 0.0035
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0058 0.0539
Loa Loa (eye worm) glutamate receptor 0.013 0.0279 0.053
Schistosoma mansoni pap-inositol-14-phosphatase 0.0012 0.0001 0.0001
Schistosoma mansoni alpha-1 adrenergic receptor 0.0958 0.2226 0.2226
Schistosoma mansoni terminal deoxycytidyl transferase 0.0059 0.0111 0.0111
Loa Loa (eye worm) hypothetical protein 0.0958 0.2226 0.4225
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0041 0.007 0.0133
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0062 0.0119 0.0226
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0038 0.0062 0.0117
Plasmodium falciparum phosphodiesterase gamma, putative 0.0017 0.0014 0.0877
Echinococcus multilocularis inositol monophosphatase 1 0.0112 0.0236 0.0298
Mycobacterium tuberculosis Conserved protein 0.0035 0.0055 0.0234
Echinococcus granulosus dro:myosuppressin receptor 0.0958 0.2226 0.4225
Trypanosoma cruzi DNA polymerase eta, putative 0.0085 0.0174 0.5727
Mycobacterium tuberculosis Conserved protein 0.0036 0.0057 0.0242
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0062 0.0119 0.1108
Onchocerca volvulus 0.0958 0.2226 0.6779
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0074 0.0146 0.0619
Mycobacterium ulcerans hypothetical protein 0.0035 0.0055 0.0231
Brugia malayi Patched related family protein 12 0.0025 0.0031 0.006
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0059 0.0111 0.0471
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.006
Loa Loa (eye worm) hypothetical protein 0.0958 0.2226 0.4225
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0958 0.2226 0.2812
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0058 0.1916
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0958 0.2226 0.2812
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0024 0.0099
Loa Loa (eye worm) animal heme peroxidase 0.1408 0.3283 0.6231
Trypanosoma cruzi trypanothione reductase, putative 0.0016 0.0011 0.0372
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0019 0.0019 0.0036
Echinococcus multilocularis neuropeptide Y receptor 0.0958 0.2226 0.2812
Giardia lamblia Kinase, PLK 0.0095 0.0198 1
Loa Loa (eye worm) hypothetical protein 0.0958 0.2226 0.4225
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0036 0.0058 0.0615
Brugia malayi Receptor family ligand binding region containing protein 0.0033 0.0052 0.0098
Brugia malayi hypothetical protein 0.0019 0.0019 0.0036
Onchocerca volvulus 0.0025 0.0031 0.0094
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0003
Trichomonas vaginalis DNA helicase recq, putative 0.0025 0.0032 0.0298
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0017 0.0013 0.0483
Echinococcus granulosus peroxidasin 0.1408 0.3283 0.6231
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0141 0.0304 0.2836
Echinococcus multilocularis G protein coupled receptor 139 0.0958 0.2226 0.2812
Toxoplasma gondii histone lysine methyltransferase SET1 0.0041 0.0068 0.2604
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0057 0.1874
Onchocerca volvulus 0.0025 0.0031 0.0094
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0958 0.2226 0.2226
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.0141 0.0304 0.0384
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0958 0.2226 0.2812
Plasmodium vivax SET domain protein, putative 0.0059 0.0112 0.7221
Brugia malayi Copper type II ascorbate-dependent monooxygenase, C-terminal domain containing protein 0.2252 0.5269 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0958 0.2226 0.4225
Plasmodium vivax multidomain scavenger receptor, putative 0.0039 0.0065 0.4186
Entamoeba histolytica hypothetical protein 0.0019 0.0019 0.0192
Schistosoma mansoni adenoreceptor 0.0958 0.2226 0.2226
Mycobacterium ulcerans hypothetical protein 0.0018 0.0016 0.0065
Loa Loa (eye worm) hypothetical protein 0.0041 0.007 0.0133
Echinococcus multilocularis 3'(2'),5' bisphosphate nucleotidase 1 0.0012 0.0001 0.0001
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0022 0.0024 0.0101
Echinococcus granulosus snurportin 1 0.0328 0.0744 0.1413
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0059 0.0112 0.0112
Mycobacterium tuberculosis Probable DNA polymerase III (alpha chain) DnaE2 (DNA nucleotidyltransferase) 0.1012 0.2352 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.0019 0.0036
Brugia malayi polk-prov protein 0.0018 0.0016 0.003
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.006
Loa Loa (eye worm) hypothetical protein 0.1408 0.3283 0.6231
Echinococcus granulosus Protein patched homolog 1 0.0176 0.0387 0.0734
Trypanosoma brucei DNA polymerase kappa, putative 0.0059 0.0111 0.3649
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0958 0.2226 0.2226
Brugia malayi Nuclear hormone receptor-like 1 0.0041 0.007 0.0133
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0031 0.0045 0.0085
Echinococcus granulosus thioredoxin glutathione reductase 0.0047 0.0084 0.0159
Brugia malayi exodeoxyribonuclease III family protein 0.0038 0.0062 0.0117
Loa Loa (eye worm) hypothetical protein 0.0958 0.2226 0.4225
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0045 0.0079 0.2998
Mycobacterium tuberculosis Conserved protein 0.0036 0.0057 0.0242
Brugia malayi ecdysteroid receptor 0.0041 0.007 0.0133
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0057 0.0527
Brugia malayi hypothetical protein 0.0121 0.0258 0.0491
Loa Loa (eye worm) hypothetical protein 0.0958 0.2226 0.4225
Brugia malayi Copper type II ascorbate-dependent monooxygenase, N-terminal domain containing protein 0.1143 0.266 0.5049
Echinococcus granulosus Polycystic kidney disease protein 0.0039 0.0065 0.0123
Leishmania major DNA polymerase eta, putative 0.0045 0.0079 0.2597
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0024 0.0099
Loa Loa (eye worm) hypothetical protein 0.1408 0.3283 0.6231
Trypanosoma brucei DNA polymerase IV, putative 0.0059 0.0111 0.3649
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0958 0.2226 0.4225
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0112 0.0236 0.1001
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.006
Echinococcus granulosus jumonji domain containing 1A 0.0017 0.0012 0.0023
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0019 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.1408 0.3283 0.6231
Loa Loa (eye worm) hypothetical protein 0.2252 0.5269 1
Echinococcus granulosus lipoxygenase domain containing protein 0.0039 0.0065 0.0123
Plasmodium falciparum glutathione reductase 0.0047 0.0084 0.5387
Brugia malayi Melatonin receptor type 1A 0.0958 0.2226 0.4225
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0022 0.0024 0.0046
Echinococcus granulosus neuropeptide receptor 0.0958 0.2226 0.4225
Schistosoma mansoni peroxidasin 0.1408 0.3283 0.3283
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0024 0.0099
Loa Loa (eye worm) hypothetical protein 0.0012 0.0001 0.0001
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0041 0.007 0.0088
Onchocerca volvulus 0.0012 0.0002 0.0004
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0057 0.0057
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.0062 0.0119 0.0226
Echinococcus multilocularis neuropeptide Y receptor 0.0958 0.2226 0.2812
Loa Loa (eye worm) hypothetical protein 0.0019 0.0019 0.0036
Brugia malayi AMP-binding enzyme family protein 0.0074 0.0146 0.0277
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.006
Loa Loa (eye worm) thioredoxin reductase 0.0047 0.0084 0.0159
Loa Loa (eye worm) hypothetical protein 0.0027 0.0038 0.0071
Schistosoma mansoni neuropeptide receptor 0.0958 0.2226 0.2226
Brugia malayi beta-lactamase family protein 0.0036 0.0057 0.0108
Loa Loa (eye worm) hypothetical protein 0.0019 0.0019 0.0036
Echinococcus granulosus tm gpcr rhodopsin 0.0958 0.2226 0.4225
Leishmania major hypothetical protein, conserved 0.0017 0.0014 0.0448
Echinococcus multilocularis peptidyl glycine alpha amidating monooxygenase 0.2252 0.5269 0.6657
Brugia malayi Guanylyl cyclase protein 23 0.0012 0.0002 0.0003
Brugia malayi ImpB/MucB/SamB family protein 0.0059 0.0111 0.021
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0017 0.0014 0.0026
Loa Loa (eye worm) hypothetical protein 0.0958 0.2226 0.4225
Leishmania major 4-coumarate:coa ligase-like protein 0.0074 0.0146 0.4811
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0022 0.0024 0.0099
Brugia malayi G protein-coupled receptor 0.0958 0.2226 0.4225
Onchocerca volvulus 0.0306 0.0691 0.2105
Echinococcus multilocularis cpg binding protein 0.0021 0.0023 0.003
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0095 0.0198 0.6507
Loa Loa (eye worm) hypothetical protein 0.0019 0.0019 0.0036
Trichomonas vaginalis glutathione reductase, putative 0.0016 0.0011 0.0101
Loa Loa (eye worm) animal heme peroxidase 0.1408 0.3283 0.6231
Leishmania major DNA polymerase eta, putative 0.0085 0.0174 0.5727
Echinococcus granulosus histone lysine methyltransferase setb 0.0059 0.0112 0.0213
Loa Loa (eye worm) calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase 0.0017 0.0014 0.0026
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0012 0.0002 0.0002
Schistosoma mansoni thyroid hormone receptor 0.0041 0.007 0.007
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0041 0.007 0.0088
Brugia malayi Patched family protein 0.0025 0.0031 0.006
Echinococcus granulosus lysine specific demethylase 5A 0.0064 0.0123 0.0234
Schistosoma mansoni retinoic acid receptor RXR 0.0041 0.007 0.007
Plasmodium falciparum lipid/sterol:H+ symporter 0.0025 0.0031 0.2027
Onchocerca volvulus 0.002 0.0021 0.0061
Brugia malayi Inositol-1 0.0112 0.0236 0.0448
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.006
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.006
Trypanosoma cruzi DNA polymerase kappa, putative 0.0059 0.0111 0.3649
Echinococcus multilocularis JmjC domain containing protein 4 0.0017 0.0012 0.0016
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0058 0.0539
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0003
Onchocerca volvulus 0.0958 0.2226 0.6779
Schistosoma mansoni cellular tumor antigen P53 0.0049 0.0088 0.0088
Onchocerca volvulus Peroxidasin homolog 0.1408 0.3283 1
Trypanosoma brucei polo-like protein kinase 0.0095 0.0198 0.6507
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0055 0.0102 0.0433
Echinococcus granulosus metabotropic glutamate receptor 2 0.0109 0.023 0.0436
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0016 0.0011 0.0046
Schistosoma mansoni transcription factor LCR-F1 0.0076 0.0151 0.0151
Loa Loa (eye worm) metabotropic GABA-B receptor subtype 2 0.0033 0.0052 0.0098
Loa Loa (eye worm) hypothetical protein 0.1408 0.3283 0.6231
Entamoeba histolytica hypothetical protein 0.0076 0.0151 0.1602
Schistosoma mansoni serine/threonine protein kinase 0.0095 0.0198 0.0198
Loa Loa (eye worm) hypothetical protein 0.0121 0.0258 0.0491
Onchocerca volvulus 0.0022 0.0024 0.0071
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0041 0.007 0.0133
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0141 0.0304 0.2836
Trypanosoma cruzi extracellular receptor, putative 0.0012 0.0002 0.0059
Brugia malayi hypothetical protein 0.0019 0.0019 0.0035
Echinococcus multilocularis lysosomal alpha glucosidase 0.0163 0.0357 0.0451
Echinococcus multilocularis FTZ F1 alpha 0.0041 0.007 0.0088
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0059 0.0111 0.0111
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0038 0.0062 0.0262
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0107 0.0225 0.0958
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0059 0.0112 0.0112
Echinococcus granulosus neuropeptides capa receptor 0.0958 0.2226 0.4225
Mycobacterium tuberculosis Probable conserved exported protein 0.0035 0.0055 0.0234
Echinococcus granulosus metabotropic glutamate receptor 5 0.016 0.035 0.0665
Schistosoma mansoni biogenic amine (5HT) receptor 0.0958 0.2226 0.2226
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0958 0.2226 0.4225
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0017 0.0014 0.0017
Schistosoma mansoni cpg binding protein 0.0021 0.0023 0.0023
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0016 0.0011 0.0729
Loa Loa (eye worm) DOMON domain-containing protein 0.0431 0.0987 0.1873
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0096 0.0198 0.185
Loa Loa (eye worm) hypothetical protein 0.0019 0.0019 0.0036
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0011 0.0372
Brugia malayi G-protein coupled receptor 0.0958 0.2226 0.4225
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0958 0.2226 0.2226
Plasmodium falciparum DNA repair protein REV1, putative 0.0018 0.0016 0.1015
Toxoplasma gondii LsmAD domain-containing protein 0.0077 0.0155 0.5901
Brugia malayi Glycosyl hydrolases family 31 protein 0.0036 0.0058 0.011
Onchocerca volvulus 0.1408 0.3283 1
Loa Loa (eye worm) hypothetical protein 0.0017 0.0014 0.0026
Trichomonas vaginalis alpha-glucosidase, putative 0.0013 0.0005 0.0039
Schistosoma mansoni metabotropic glutamate receptor 0.0109 0.023 0.023
Echinococcus granulosus g protein coupled receptor 0.0958 0.2226 0.4225
Trypanosoma brucei cAMP-specific phosphodiesterase, putative 0.0017 0.0014 0.0448
Plasmodium vivax JmjC domain containing protein 0.0017 0.0012 0.0792
Loa Loa (eye worm) hypothetical protein 0.1408 0.3283 0.6231
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0023 0.0026 0.1301
Schistosoma mansoni axis inhibition protein axin 0.0019 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.0958 0.2226 0.4225
Trypanosoma brucei hypothetical protein, conserved 0.0018 0.0016 0.0519
Trichomonas vaginalis antibiotic synthetase, putative 0.0022 0.0024 0.0218
Loa Loa (eye worm) hypothetical protein 0.0036 0.0057 0.0108
Brugia malayi AKH receptor 0.0958 0.2226 0.4225
Loa Loa (eye worm) RGC/RGC protein kinase 0.0012 0.0002 0.0003
Leishmania major trypanothione reductase 0.0047 0.0084 0.2753
Loa Loa (eye worm) hypothetical protein 0.0031 0.0045 0.0086
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0035 0.0056 0.0106
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0017 0.0014 0.0518
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0052 0.0095 0.0405
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0017 0.0014 0.0014
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0958 0.2226 0.4225
Brugia malayi hypothetical protein 0.0958 0.2226 0.4225
Brugia malayi Animal haem peroxidase family protein 0.1408 0.3283 0.6231
Mycobacterium ulcerans secreted antigen 85-A FbpA 0.0035 0.0055 0.0231
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0019 0.0019 0.0019
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0141 0.0304 0.2836
Echinococcus granulosus thyroid hormone receptor alpha 0.0019 0.0019 0.0036
Brugia malayi Copper type II ascorbate-dependent monooxygenase, C-terminal domain containing protein 0.1109 0.2581 0.4899
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.0011 0.0372
Toxoplasma gondii thioredoxin reductase 0.0047 0.0084 0.3179
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0135 0.0291 0.0291
Mycobacterium tuberculosis Probable lipase LipD 0.0036 0.0057 0.0242
Echinococcus multilocularis g protein coupled receptor 0.0958 0.2226 0.2812
Toxoplasma gondii hypothetical protein 0.0123 0.0263 1
Onchocerca volvulus 0.0039 0.0065 0.0196
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0041 0.007 0.0133
Entamoeba histolytica hypothetical protein 0.0076 0.0151 0.1602
Echinococcus granulosus 7TM GPCR rhodopsin 0.0958 0.2226 0.4225
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0024 0.0099
Trypanosoma brucei unspecified product 0.004 0.0068 0.224
Trypanosoma brucei glycosyl hydrolase-like protein 0.0013 0.0005 0.0155
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0017 0.0014 0.0518
Loa Loa (eye worm) hypothetical protein 0.0958 0.2226 0.4225
Leishmania major hypothetical protein, conserved 0.0017 0.0014 0.0448
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0019 0.0019
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0141 0.0304 0.2836
Entamoeba histolytica hypothetical protein 0.0019 0.0019 0.0192
Brugia malayi Probable 3',5'-cyclic phosphodiesterase T04D3.3, putative 0.0017 0.0014 0.0026
Trichomonas vaginalis conserved hypothetical protein 0.0123 0.0263 0.2455
Loa Loa (eye worm) animal heme peroxidase 0.1408 0.3283 0.6231
Echinococcus multilocularis lysine specific demethylase 5A 0.0063 0.012 0.0152
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0023 0.0026 0.0995
Brugia malayi protein C24B5.3 0.0025 0.0031 0.006
Mycobacterium tuberculosis Possible conserved membrane protein 0.0035 0.0055 0.0234
Brugia malayi hypothetical protein 0.0039 0.0065 0.0123
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0074 0.0146 0.0621
Loa Loa (eye worm) hypothetical protein 0.0077 0.0155 0.0294
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.006
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0038 0.0062 0.2032
Schistosoma mansoni amine GPCR 0.0958 0.2226 0.2226
Schistosoma mansoni metabotropic glutamate receptor 2 3 (mglur group 2) 0.0148 0.0321 0.0321
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0017 0.0012 0.0467
Trichomonas vaginalis alpha-glucosidase, putative 0.0013 0.0005 0.0039
Trypanosoma brucei PAB1-binding protein , putative 0.0077 0.0155 0.5111
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0058 0.0539
Onchocerca volvulus 0.0958 0.2226 0.6779
Echinococcus granulosus 3'2'5' bisphosphate nucleotidase 1 0.0012 0.0001 0.0001
Mycobacterium ulcerans secreted antigen 85-C FbpC 0.0821 0.1903 0.8091
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0063 0.012 0.0152
Schistosoma mansoni neuropeptide f receptor 76f 0.0958 0.2226 0.2226
Loa Loa (eye worm) hypothetical protein 0.0035 0.0056 0.0106
Echinococcus multilocularis fmrfamide receptor 0.0958 0.2226 0.2812
Brugia malayi beta-lactamase 0.0036 0.0057 0.0108
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0036 0.0058 0.0615
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0038 0.0062 0.2032
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0041 0.007 0.0133
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0019 0.0019 0.0019
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0012 0.0002 0.0002
Onchocerca volvulus 0.0958 0.2226 0.6779
Echinococcus multilocularis high affinity cAMP specific 3',5' cyclic 0.0017 0.0014 0.0017
Giardia lamblia CAMP-specific 3,5-cyclic phosphodiesterase 4B 0.0017 0.0014 0.0664
Mycobacterium ulcerans putative regulatory protein 0.0045 0.0078 0.0331
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0958 0.2226 0.2226
Echinococcus multilocularis g-protein coupled receptor 0.0958 0.2226 0.2812
Brugia malayi Receptor family ligand binding region containing protein 0.0012 0.0002 0.0003
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0016 0.0011 0.0372
Loa Loa (eye worm) hypothetical protein 0.0958 0.2226 0.4225
Schistosoma mansoni nuclear receptor nhr-48 0.0019 0.0019 0.0019
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0112 0.0236 0.8976
Loa Loa (eye worm) hypothetical protein 0.1408 0.3283 0.6231
Echinococcus granulosus cpg binding protein 0.0021 0.0023 0.0044
Mycobacterium ulcerans acyl-CoA synthetase 0.0074 0.0146 0.0619
Echinococcus multilocularis ecdysone induced protein 78C 0.0041 0.007 0.0088
Brugia malayi latrophilin 2 splice variant baaae 0.0024 0.003 0.0056
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0141 0.0304 0.2836
Onchocerca volvulus 0.0012 0.0002 0.0004
Loa Loa (eye worm) hypothetical protein 0.0019 0.0019 0.0036
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0017 0.0014 0.0122
Plasmodium falciparum ataxin-2 like protein, putative 0.0077 0.0155 1
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0016 0.0011 0.0021
Echinococcus granulosus axis inhibition protein axin 0.0019 0.0019 0.0035
Brugia malayi Patched family protein 0.0025 0.0031 0.006
Mycobacterium tuberculosis Secreted MPT51/MPB51 antigen protein FbpD (MPT51/MPB51 antigen 85 complex C) (AG58C) (mycolyl transferase 85C) (fibronectin-bind 0.0035 0.0055 0.0234
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0022 0.0024 0.0784
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0022 0.0024 0.0101
Schistosoma mansoni hypothetical protein 0.0024 0.003 0.003
Brugia malayi serine/threonine-protein kinase plk-2 0.0095 0.0198 0.0375
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0058 0.0539
Echinococcus multilocularis dnaJ subfamily B 0.0289 0.0653 0.0825
Loa Loa (eye worm) hypothetical protein 0.0019 0.0019 0.0036
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0958 0.2226 0.2226
Onchocerca volvulus 0.0022 0.0024 0.0071
Onchocerca volvulus 0.0036 0.0057 0.0172
Schistosoma mansoni ran 0.0023 0.0026 0.0026
Loa Loa (eye worm) hypothetical protein 0.0026 0.0035 0.0067
Loa Loa (eye worm) nuclear receptor NHR-67 0.0019 0.0019 0.0036
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0017 0.0014 0.0518
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0019 0.0019
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0017 0.0014 0.0518
Loa Loa (eye worm) patched family protein 0.0025 0.0031 0.006
Trypanosoma brucei unspecified product 0.004 0.0068 0.224
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0041 0.007 0.007
Loa Loa (eye worm) nuclear hormone receptor 0.0019 0.0019 0.0036
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0078 0.0728
Schistosoma mansoni RAR-like nuclear receptor 0.0041 0.007 0.007
Echinococcus granulosus JmjC domain containing protein 4 0.0017 0.0012 0.0023
Brugia malayi Patched family protein 0.0025 0.0031 0.006
Echinococcus multilocularis neuropeptides capa receptor 0.0958 0.2226 0.2812
Plasmodium falciparum phosphodiesterase delta, putative 0.0017 0.0014 0.0877
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0017 0.0014 0.0877
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0016 0.0011 0.0372
Onchocerca volvulus 0.0958 0.2226 0.6779
Trypanosoma brucei glucosidase, putative 0.0036 0.0058 0.1916
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0041 0.007 0.0133
Trichomonas vaginalis set domain proteins, putative 0.0466 0.1069 1
Trichomonas vaginalis conserved hypothetical protein 0.0123 0.0263 0.2455
Trypanosoma cruzi DNA polymerase kappa, putative 0.0059 0.0111 0.3649
Trypanosoma brucei importin beta-1 subunit, putative 0.0031 0.0045 0.149
Trypanosoma cruzi hypothetical protein, conserved 0.0017 0.0014 0.0448
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0011 0.0372
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.006
Mycobacterium ulcerans two component sensor histidine kinase DevS 0.0045 0.0078 0.0331
Brugia malayi neuropeptide F receptor 0.0958 0.2226 0.4225
Echinococcus multilocularis GPCR, family 3, C terminal 0.0021 0.0023 0.0029
Schistosoma mansoni inositol monophosphatase 0.0112 0.0236 0.0236
Schistosoma mansoni neuropeptide receptor 0.0958 0.2226 0.2226
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0135 0.0291 0.0552
Loa Loa (eye worm) hypothetical protein 0.1408 0.3283 0.6231
Loa Loa (eye worm) hypothetical protein 0.0019 0.0019 0.0035
Onchocerca volvulus 0.0059 0.0112 0.034
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.0141 0.0304 0.0576
Echinococcus granulosus peptide allatostatin:somatostatin 0.0958 0.2226 0.4225
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0958 0.2226 0.2226
Trypanosoma brucei hypothetical protein, conserved 0.0018 0.0016 0.0519
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0958 0.2226 0.4225
Echinococcus granulosus Niemann Pick C1 protein 0.041 0.0937 0.1779
Schistosoma mansoni amine GPCR 0.0958 0.2226 0.2226
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0036 0.0057 0.0108
Loa Loa (eye worm) hypothetical protein 0.0958 0.2226 0.4225
Echinococcus multilocularis muscleblind protein 0.0159 0.0347 0.0439
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0036 0.0058 0.0539
Leishmania major hypothetical protein, conserved 0.0036 0.0057 0.1874
Echinococcus granulosus g protein coupled receptor 0.0958 0.2226 0.4225
Brugia malayi jmjC domain containing protein 0.0017 0.0012 0.0023
Brugia malayi hypothetical protein 0.0958 0.2226 0.4225
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0003
Toxoplasma gondii aldehyde dehydrogenase 0.0065 0.0125 0.476
Loa Loa (eye worm) hypothetical protein 0.0059 0.0112 0.0213
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0012 0.0002 0.0003
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.002 0.0019 0.0037
Trypanosoma brucei DNA polymerase kappa, putative 0.0018 0.0016 0.0519
Trypanosoma cruzi cyclic nucleotide phosphodiesterase 0.0017 0.0014 0.0448
Loa Loa (eye worm) hypothetical protein 0.0019 0.0019 0.0035
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.0011 0.0372
Onchocerca volvulus 0.0431 0.0987 0.3005
Onchocerca volvulus 0.0958 0.2226 0.6779
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0112 0.0236 0.7774
Brugia malayi Patched family protein 0.0025 0.0031 0.006
Echinococcus granulosus RUN 0.0039 0.0065 0.0123
Echinococcus multilocularis rhodopsin orphan GPCR 0.0958 0.2226 0.2812
Loa Loa (eye worm) hypothetical protein 0.0041 0.007 0.0133
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0038 0.0062 0.0653
Brugia malayi Patched family protein 0.0025 0.0031 0.006
Brugia malayi Glycosyl hydrolases family 31 protein 0.0163 0.0357 0.0677
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0958 0.2226 0.2812
Schistosoma mansoni cpg binding protein 0.0021 0.0023 0.0023
Echinococcus multilocularis rhodopsin orphan GPCR 0.0958 0.2226 0.2812
Mycobacterium tuberculosis Probable reductase 0.0107 0.0225 0.0958
Brugia malayi hypothetical protein 0.0025 0.0031 0.006
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0119 0.0253 0.1076
Onchocerca volvulus 0.1408 0.3283 1
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0096 0.0198 0.6531
Brugia malayi Patched family protein 0.0025 0.0031 0.006
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0135 0.0291 0.0291
Loa Loa (eye worm) jmjC domain-containing protein 0.0017 0.0012 0.0023
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.0141 0.0304 0.2836
Echinococcus multilocularis dna polymerase kappa 0.0059 0.0111 0.014
Echinococcus granulosus inositol monophosphatase 1 0.0112 0.0236 0.0448
Echinococcus multilocularis metabotropic glutamate receptor 2 0.0109 0.023 0.029
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0016 0.0011 0.0729
Brugia malayi hypothetical protein 0.1408 0.3283 0.6231
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0019 0.0019 0.0024
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0041 0.007 0.0088
Echinococcus granulosus GPCR family 3 C terminal 0.0021 0.0023 0.0043
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0141 0.0304 0.2836
Brugia malayi Patched family protein 0.0025 0.0031 0.006
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0017 0.0014 0.0448
Loa Loa (eye worm) hypothetical protein 0.0017 0.0012 0.0023
Schistosoma mansoni intermediate filament proteins 0.0057 0.0107 0.0107
Leishmania major 4-coumarate:coa ligase-like protein 0.0074 0.0146 0.4811
Schistosoma mansoni importin beta-1 0.0031 0.0045 0.0045
Brugia malayi AMP-binding enzyme family protein 0.0022 0.0024 0.0045
Echinococcus granulosus regulator of G protein signaling 7 0.0019 0.0019 0.0035
Echinococcus granulosus rhodopsin orphan GPCR 0.0958 0.2226 0.4225
Schistosoma mansoni amine GPCR 0.0958 0.2226 0.2226
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.006
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0057 0.0107 0.0203
Echinococcus granulosus hypothetical protein 0.0958 0.2226 0.4225
Schistosoma mansoni acetyl-CoA synthetase 0.0022 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.0958 0.2226 0.4225
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0141 0.0304 0.2836
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0141 0.0304 0.2836
Loa Loa (eye worm) hypothetical protein 0.0159 0.0347 0.0659
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0958 0.2226 0.4225
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0065 0.0125 0.0532
Mycobacterium leprae conserved hypothetical protein 0.0036 0.0057 0.024
Echinococcus multilocularis Niemann Pick C1 protein 0.0586 0.1351 0.1707
Plasmodium falciparum acyl-CoA synthetase 0.0055 0.0102 0.6594
Loa Loa (eye worm) patched family protein 0.0025 0.0031 0.006
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0017 0.0014 0.0026
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0018 0.0016 0.0599
Echinococcus multilocularis glutamate receptor 2 0.0012 0.0002 0.0002
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0107 0.0225 0.0956
Loa Loa (eye worm) hypothetical protein 0.0036 0.0057 0.0108
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0023 0.0026 0.0033
Brugia malayi Nuclear hormone receptor-like 1 0.0022 0.0024 0.0046
Schistosoma mansoni microtubule-associated protein tau 0.0488 0.112 0.112
Trypanosoma brucei DNA polymerase kappa, putative 0.0059 0.0111 0.3649
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0958 0.2226 0.2812
Trichomonas vaginalis alpha-glucosidase, putative 0.0013 0.0005 0.0039
Entamoeba histolytica hypothetical protein 0.0076 0.0151 0.1602
Trypanosoma brucei DNA polymerase eta, putative 0.0085 0.0174 0.5727
Echinococcus multilocularis regulator of G protein signaling 7 0.0019 0.0019 0.0023
Entamoeba histolytica Ran family GTPase 0.0023 0.0026 0.0274
Loa Loa (eye worm) hypothetical protein 0.0958 0.2226 0.4225
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0068 0.224
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0958 0.2226 0.2226
Echinococcus multilocularis receptor type guanylyl cyclase 0.0012 0.0002 0.0002
Brugia malayi ORL1-like opioid receptor 0.0958 0.2226 0.4225
Mycobacterium ulcerans DNA polymerase IV 0.0059 0.0111 0.0469
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.0011 0.0372
Schistosoma mansoni lamin 0.0057 0.0107 0.0107
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0041 0.007 0.007
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0011 0.0372
Echinococcus multilocularis axis inhibition protein axin 0.0019 0.0019 0.0023
Schistosoma mansoni hypothetical protein 0.0958 0.2226 0.2226
Echinococcus granulosus Regulator of G protein signaling 20 0.0019 0.0019 0.0035
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0958 0.2226 0.4225
Trypanosoma brucei DNA damage repair protein, putative 0.0018 0.0016 0.0519
Entamoeba histolytica acyl-CoA synthetase, putative 0.0074 0.0146 0.1554
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0012 0.0002 0.0003
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0012 0.0002 0.0003
Brugia malayi Importin beta-1 subunit 0.0031 0.0045 0.0086
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0041 0.007 0.007
Brugia malayi hypothetical protein 0.0012 0.0002 0.0003
Brugia malayi hypothetical protein 0.0306 0.0691 0.1312
Entamoeba histolytica hypothetical protein 0.0012 0.0002 0.0013
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0059 0.0112 0.0142
Schistosoma mansoni biogenic amine receptor 0.0958 0.2226 0.2226
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.041 0.0936 0.1777
Brugia malayi regulator of G-protein signaling egl-10 0.0019 0.0019 0.0035
Brugia malayi Tachykinin-like peptides receptor 99D 0.0958 0.2226 0.4225
Echinococcus multilocularis rhodopsin orphan GPCR 0.0958 0.2226 0.2812
Brugia malayi Patched family protein 0.0025 0.0031 0.006
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0022 0.0024 0.0024
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0074 0.0146 0.0621
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0062 0.0119 0.1108
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0017 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0022 0.0024 0.0045
Brugia malayi nuclear receptor NHR-88 0.0041 0.007 0.0133
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0065 0.0125 0.0238
Loa Loa (eye worm) hypothetical protein 0.0039 0.0065 0.0123
Echinococcus multilocularis neuropeptide FF receptor 2 0.0958 0.2226 0.2812
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0041 0.007 0.0133
Trypanosoma brucei hypothetical protein, conserved 0.0036 0.0057 0.1874
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0019 0.0168
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0022 0.0024 0.0045
Brugia malayi Myosin head containing protein 0.0025 0.0031 0.006
Mycobacterium ulcerans esterase/lipase LipP 0.0036 0.0057 0.024
Echinococcus granulosus rhodopsin orphan GPCR 0.0958 0.2226 0.4225
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0112 0.0236 0.096
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0017 0.0014 0.0122
Schistosoma mansoni neuropeptide receptor 0.0958 0.2226 0.2226
Echinococcus granulosus tm gpcr rhodopsin 0.0958 0.2226 0.4225
Echinococcus granulosus fmrfamide receptor 0.0958 0.2226 0.4225
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0041 0.007 0.0133
Mycobacterium tuberculosis Probable esterase LipL 0.0036 0.0057 0.0242
Schistosoma mansoni hypothetical protein 0.017 0.0372 0.0372
Trypanosoma brucei DNA polymerase kappa, putative 0.0059 0.0111 0.3649
Schistosoma mansoni biogenic amine receptor 0.0958 0.2226 0.2226
Schistosoma mansoni ap endonuclease 0.0038 0.0062 0.0062
Brugia malayi AMP-binding enzyme family protein 0.0074 0.0146 0.0277
Onchocerca volvulus 0.0057 0.0107 0.0324
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0022 0.0024 0.0101
Brugia malayi Esterase D 0.0035 0.0055 0.0104
Loa Loa (eye worm) TYRA-2 protein 0.0958 0.2226 0.4225
Brugia malayi RE15519p 0.0958 0.2226 0.4225
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0019 0.0017 0.0071
Trypanosoma cruzi DNA polymerase kappa, putative 0.0059 0.0111 0.3649
Schistosoma mansoni protein kinase 0.0012 0.0002 0.0002
Echinococcus multilocularis neuropeptide receptor A26 0.0958 0.2226 0.2812
Brugia malayi larval opioid receptor 0.0958 0.2226 0.4225
Echinococcus multilocularis lamin 0.0057 0.0107 0.0135
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0057 0.0527
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0141 0.0304 0.2836
Mycobacterium tuberculosis Probable lipase LipE 0.0036 0.0057 0.0242
Schistosoma mansoni jumonji domain containing protein 0.0063 0.012 0.012
Trichomonas vaginalis conserved hypothetical protein 0.0176 0.0387 0.3614
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0019 0.0019 0.0024
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.002 0.0019 0.0037
Loa Loa (eye worm) hypothetical protein 0.0019 0.0019 0.0036
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0041 0.007 0.0133
Loa Loa (eye worm) hypothetical protein 0.0958 0.2226 0.4225
Leishmania major inositol polyphosphate 1-phosphatase, putative 0.0012 0.0001 0.0018
Echinococcus multilocularis neutral alpha glucosidase AB 0.0036 0.0058 0.0074
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0017 0.0014 0.0518
Echinococcus granulosus biogenic amine 5HT receptor 0.0958 0.2226 0.4225
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0112 0.0236 0.2514
Brugia malayi putative neuropeptide receptor 0.0958 0.2226 0.4225
Trypanosoma brucei hypothetical protein, conserved 0.0017 0.0014 0.0448
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0013 0.0005 0.0155
Mycobacterium ulcerans acyl-CoA synthetase 0.0074 0.0146 0.0619
Loa Loa (eye worm) hypothetical protein 0.0041 0.007 0.0133
Echinococcus granulosus lysine specific demethylase 6a 0.0017 0.0012 0.0023
Echinococcus granulosus inositol monophosphatase 0.0012 0.0001 0.0001
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0017 0.0014 0.0014
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0017 0.0014 0.0026
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.006
Mycobacterium leprae SECRETED ANTIGEN 85-B FBPB (85B) (ANTIGEN 85 COMPLEX B) (MYCOLYL TRANSFERASE 85B) (FIBRONECTIN-BINDING PROTEIN B) (EXTRACELLULAR 0.0035 0.0055 0.0231
Echinococcus granulosus neuropeptides capa receptor 0.0958 0.2226 0.4225
Schistosoma mansoni myo inositol monophosphatase 0.0012 0.0001 0.0001
Plasmodium falciparum glutathione reductase 0.0016 0.0011 0.0729
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0041 0.007 0.0133
Onchocerca volvulus 0.0036 0.0057 0.0172
Loa Loa (eye worm) hypothetical protein 0.016 0.035 0.0665
Loa Loa (eye worm) receptor family ligand binding region containing protein 0.0033 0.0052 0.0098
Leishmania major 4-coumarate:coa ligase-like protein 0.0074 0.0146 0.4811
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0958 0.2226 0.4225
Plasmodium vivax glutathione reductase, putative 0.0047 0.0084 0.5387
Mycobacterium leprae Probable lipase LipE 0.0036 0.0057 0.024
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.011 0.023 0.0291
Entamoeba histolytica acyl-CoA synthetase, putative 0.0074 0.0146 0.1554
Loa Loa (eye worm) hypothetical protein 0.0958 0.2226 0.4225
Loa Loa (eye worm) intermediate filament protein 0.0057 0.0107 0.0203
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0023 0.0026 0.1686
Echinococcus granulosus biogenic amine 5HT receptor 0.0958 0.2226 0.4225
Loa Loa (eye worm) hypothetical protein 0.0017 0.0012 0.0023
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0017 0.0014 0.0014
Trichomonas vaginalis conserved hypothetical protein 0.0141 0.0304 0.2836
Toxoplasma gondii hypothetical protein 0.0045 0.0078 0.2978
Brugia malayi hypothetical protein 0.0076 0.0151 0.0286
Giardia lamblia Hypothetical protein 0.0017 0.0014 0.0664
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0019 0.0019
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0058 0.0539
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0023 0.0026 0.0862
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0059 0.0111 0.3649
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0052 0.0095 0.0405
Echinococcus multilocularis nuclear receptor nhr 48 0.0019 0.0019 0.0024
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0017 0.0014 0.0518
Schistosoma mansoni nuclear hormone receptor 0.0019 0.0019 0.0019
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0041 0.007 0.0133
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.0198 0.1843
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0016 0.0011 0.0046
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0141 0.0304 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0059 0.0112 0.0112
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0141 0.0304 0.2836
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0059 0.0111 0.021
Mycobacterium ulcerans secreted antigen 85-B FbpB 0.0035 0.0055 0.0231
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.006
Brugia malayi orphan nuclear receptor NR2E1 0.0019 0.0019 0.0036
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.006
Chlamydia trachomatis DNA polymerase III subunit alpha 0.1012 0.2352 1
Mycobacterium tuberculosis Probable hydrolase 0.0036 0.0057 0.0242
Brugia malayi nuclear receptor RXR 0.0019 0.0019 0.0036
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.0198 0.1843
Brugia malayi Metabotropic glutamate receptor precursor. 0.013 0.0279 0.053
Plasmodium vivax cyclic nucleotide phosphodiesterase, putative 0.0017 0.0014 0.0877
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0017 0.0014 0.0017
Entamoeba histolytica deoxycytidyl transferase, putative 0.0059 0.0111 0.1177
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0013 0.0005 0.0155
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0017 0.0014 0.0014
Loa Loa (eye worm) RGC/RGC protein kinase 0.0012 0.0002 0.0003
Toxoplasma gondii NADPH-glutathione reductase 0.0016 0.0011 0.043
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0003
Echinococcus multilocularis regulator of G protein signaling 3 0.0019 0.0019 0.0023
Echinococcus granulosus 7tm_1 domain containing protein 0.0958 0.2226 0.4225
Mycobacterium tuberculosis Probable monophosphatase 0.0012 0.0001 0.0002
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0019 0.0168
Echinococcus multilocularis Regulator of G protein signaling 20 0.0019 0.0019 0.0023
Leishmania major acetyl-CoA synthetase, putative 0.0022 0.0024 0.0784
Toxoplasma gondii patched family protein 0.0025 0.0031 0.1196
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0958 0.2226 0.2812
Mycobacterium tuberculosis Secreted antigen 85-B FbpB (85B) (antigen 85 complex B) (mycolyl transferase 85B) (fibronectin-binding protein B) (extracellular 0.0035 0.0055 0.0234
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0141 0.0304 0.2836
Loa Loa (eye worm) jmjC domain-containing protein 0.0017 0.0012 0.0023
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0013 0.0005 0.0039
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0022 0.0024 0.0101
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0019 0.0019 0.0055
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0017 0.0014 0.0122
Echinococcus granulosus regulator of G protein signaling 7 0.0019 0.0019 0.0035
Toxoplasma gondii patched family protein 0.0025 0.0031 0.1196
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0328 0.0744 0.1413
Schistosoma mansoni nuclear hormone receptor 0.0019 0.0019 0.0019
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0012 0.0002 0.0002
Echinococcus granulosus beta LACTamase domain containing family member 0.0036 0.0057 0.0108
Loa Loa (eye worm) hypothetical protein 0.0055 0.0102 0.0194
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0041 0.007 0.0133
Schistosoma mansoni hypothetical protein 0.0076 0.0151 0.0151
Echinococcus granulosus muscleblind protein 0.0159 0.0347 0.0659
Onchocerca volvulus 0.0958 0.2226 0.6779
Echinococcus multilocularis g protein coupled receptor 0.0958 0.2226 0.2812
Brugia malayi regulator of G-protein signaling rgs-7 0.0019 0.0019 0.0035
Brugia malayi Animal haem peroxidase family protein 0.1408 0.3283 0.6231
Entamoeba histolytica serine/threonine protein kinase, putative 0.0095 0.0198 0.2103
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0022 0.0024 0.0784
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0016 0.0011 0.0729
Giardia lamblia hypothetical protein 0.0017 0.0014 0.0664
Echinococcus granulosus microtubule associated protein 2 0.0488 0.112 0.2125
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0018 0.0016 0.0599
Brugia malayi tailless protein 0.0019 0.0019 0.0036
Brugia malayi Nuclear hormone receptor-like 1 0.0022 0.0024 0.0046
Brugia malayi Dopamine receptor 0.0958 0.2226 0.4225
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.003
Onchocerca volvulus 0.0431 0.0987 0.3005
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0958 0.2226 0.6779
Brugia malayi Calcitonin receptor-like protein seb-1 0.0035 0.0056 0.0106
Onchocerca volvulus 0.0958 0.2226 0.6779
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0019 0.0019 0.0035
Loa Loa (eye worm) hypothetical protein 0.0055 0.0102 0.0194
Entamoeba histolytica hypothetical protein 0.0019 0.0019 0.0192
Trichomonas vaginalis maltase-glucoamylase, putative 0.0013 0.0005 0.0039
Trypanosoma brucei DNA polymerase kappa, putative 0.0059 0.0111 0.3649
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0017 0.0014 0.0518
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0076 0.0151 0.0286
Mycobacterium ulcerans DNA polymerase III subunit alpha 0.1012 0.2352 1
Schistosoma mansoni opsin-like receptor 0.0958 0.2226 0.2226
Leishmania major cAMP-specific phosphodiesterase, putative 0.0017 0.0014 0.0448
Schistosoma mansoni protein phosphatase 2C 0.0017 0.0012 0.0012
Loa Loa (eye worm) MH2 domain-containing protein 0.0116 0.0246 0.0466
Loa Loa (eye worm) hypothetical protein 0.0012 0.0001 0.0001
Onchocerca volvulus 0.0958 0.2226 0.6779
Onchocerca volvulus 0.0958 0.2226 0.6779
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0017 0.0014 0.0877
Loa Loa (eye worm) patched family protein 0.0025 0.0031 0.006
Trypanosoma brucei DNA polymerase kappa, putative 0.0059 0.0111 0.3649
Schistosoma mansoni phosphatidylserine receptor 0.0017 0.0012 0.0012
Trypanosoma brucei DNA polymerase IV, putative 0.0059 0.0111 0.3649
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0041 0.007 0.0133
Echinococcus multilocularis lysosomal alpha glucosidase 0.0163 0.0357 0.0451
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0958 0.2226 0.4225
Loa Loa (eye worm) hypothetical protein 0.0041 0.007 0.0133
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0022 0.0024 0.0784
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.006
Onchocerca volvulus Peroxidase homolog 0.1408 0.3283 1
Echinococcus granulosus regulator of G protein signaling 3 0.0019 0.0019 0.0035
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.006
Brugia malayi Peroxidasin 0.1408 0.3283 0.6231
Echinococcus multilocularis jumonji domain containing 1A 0.0017 0.0012 0.0016
Echinococcus granulosus tachykinin peptides receptor 99D 0.0958 0.2226 0.4225
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0107 0.0225 0.0958
Brugia malayi Patched related family protein 10 0.0025 0.0031 0.006
Mycobacterium tuberculosis Secreted antigen 85-C FbpC (85C) (antigen 85 complex C) (AG58C) (mycolyl transferase 85C) (fibronectin-binding protein C) 0.0821 0.1903 0.8092
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0958 0.2226 0.4225
Leishmania major DNA polymerase kappa, putative 0.0018 0.0016 0.0519
Loa Loa (eye worm) hypothetical protein 0.0022 0.0024 0.0046
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.006
Brugia malayi hypothetical protein 0.0958 0.2226 0.4225
Loa Loa (eye worm) hypothetical protein 0.0056 0.0104 0.0198
Loa Loa (eye worm) hypothetical protein 0.0019 0.0019 0.0035
Echinococcus granulosus Nuclear hormone receptor HR96 0.0019 0.0019 0.0036
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0059 0.0112 0.0142
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0017 0.0014 0.0017
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0017 0.0012 0.0405
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0958 0.2226 0.2226
Echinococcus granulosus G protein coupled receptor 139 0.0958 0.2226 0.4225
Trichomonas vaginalis CAMK family protein kinase 0.0047 0.0084 0.0782
Echinococcus multilocularis rhodopsin orphan GPCR 0.0958 0.2226 0.2812
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0135 0.0291 0.0368
Schistosoma mansoni jumonji domain containing protein 0.0017 0.0012 0.0012
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0017 0.0014 0.0122
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.006
Schistosoma mansoni histamine h1 receptor 0.0958 0.2226 0.2226
Schistosoma mansoni rab6-interacting 0.0039 0.0065 0.0065
Mycobacterium ulcerans lipase LipD 0.0036 0.0057 0.024
Loa Loa (eye worm) hypothetical protein 0.0062 0.0119 0.0226
Echinococcus granulosus receptor type guanylyl cyclase 0.0012 0.0002 0.0003
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0074 0.0146 0.0619
Brugia malayi Patched protein homolog 1 0.0025 0.0031 0.006
Schistosoma mansoni metabotropic glutamate receptor 0.0064 0.0122 0.0122
Brugia malayi nuclear hormone receptor family member nhr-6 0.0019 0.0019 0.0036
Echinococcus granulosus Nuclear hormone receptor HR96 0.0019 0.0019 0.0036
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0095 0.0198 0.025
Schistosoma mansoni hypothetical protein 0.012 0.0255 0.0255
Brugia malayi RNA, U transporter 1 0.0087 0.0178 0.0339
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0059 0.0111 0.1032
Mycobacterium ulcerans hypothetical protein 0.0035 0.0055 0.0231
Echinococcus multilocularis protein patched 0.0176 0.0387 0.0489
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0012 0.0002 0.0003
Echinococcus multilocularis inositol monophosphatase 0.0012 0.0001 0.0001
Echinococcus granulosus glutamate receptor 2 0.0012 0.0002 0.0003
Trichomonas vaginalis CAMK family protein kinase 0.0047 0.0084 0.0782
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0958 0.2226 0.4225
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0141 0.0304 0.2836
Onchocerca volvulus 0.0039 0.0065 0.0196
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0141 0.0304 0.2836
Trichomonas vaginalis DNA helicase recq1, putative 0.0025 0.0032 0.0298
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.006
Onchocerca volvulus Chorion peroxidase homolog 0.1408 0.3283 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0958 0.2226 0.2226
Schistosoma mansoni aldehyde dehydrogenase 0.0065 0.0125 0.0125
Toxoplasma gondii patched family protein 0.0025 0.0031 0.1196
Loa Loa (eye worm) hypothetical protein 0.0055 0.0102 0.0194
Plasmodium vivax acetyl-CoA synthetase, putative 0.0022 0.0024 0.1534
Echinococcus multilocularis dro:myosuppressin receptor 0.0958 0.2226 0.2812
Echinococcus granulosus sex peptide receptor 0.0958 0.2226 0.4225
Loa Loa (eye worm) hypothetical protein 0.1408 0.3283 0.6231
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0958 0.2226 0.2812
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0958 0.2226 0.2226
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0141 0.0304 0.2836
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0958 0.2226 0.4225
Schistosoma mansoni camp-specific cyclic nucleotide phosphodiesterase 0.0017 0.0014 0.0014
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0036 0.0057 0.024
Toxoplasma gondii exonuclease III APE 0.0038 0.0062 0.2346
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.0198 0.1843
Loa Loa (eye worm) DOMON domain-containing protein 0.0431 0.0987 0.1873
Brugia malayi hypothetical protein 0.0958 0.2226 0.4225
Loa Loa (eye worm) hypothetical protein 0.0055 0.0102 0.0194
Brugia malayi PXA domain containing protein 0.0019 0.0019 0.0035
Brugia malayi hypothetical protein 0.0958 0.2226 0.4225
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0017 0.0012 0.0012
Trypanosoma cruzi hypothetical protein, conserved 0.0017 0.0014 0.0448
Echinococcus granulosus bloom syndrome protein 0.0025 0.0032 0.0062
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0022 0.0024 0.0045
Schistosoma mansoni hypothetical protein 0.0012 0.0001 0.0001
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0019 0.0019 0.0055
Schistosoma mansoni tyrosine kinase 0.0012 0.0002 0.0002
Brugia malayi Patched family protein 0.0025 0.0031 0.006
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0958 0.2226 0.4225
Brugia malayi Animal haem peroxidase family protein 0.1408 0.3283 0.6231
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0022 0.0024 0.0905
Onchocerca volvulus Protein patched homolog 0.0025 0.0031 0.0094
Mycobacterium ulcerans beta-lactamase 0.0036 0.0057 0.024
Echinococcus multilocularis expressed conserved protein 0.0385 0.0879 0.111
Schistosoma mansoni loxhd1 0.0039 0.0065 0.0065
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0041 0.007 0.0133
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.0198 0.1843
Plasmodium falciparum LCCL domain-containing protein 0.0039 0.0065 0.4186
Brugia malayi neuropeptide F receptor 0.0958 0.2226 0.4225
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0958 0.2226 0.2226
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0021 0.0023 0.0043
Schistosoma mansoni ap endonuclease 0.0038 0.0062 0.0062
Mycobacterium tuberculosis Two component sensor histidine kinase DosT 0.0045 0.0078 0.0333
Schistosoma mansoni zinc finger protein 0.0019 0.0019 0.0019
Echinococcus multilocularis serotonin receptor 0.0958 0.2226 0.2812
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0022 0.0024 0.0101
Loa Loa (eye worm) inositol-1 0.0112 0.0236 0.0448
Schistosoma mansoni glutamate receptor NMDA 0.0012 0.0002 0.0002
Brugia malayi sulfakinin receptor protein 0.0958 0.2226 0.4225
Loa Loa (eye worm) transcription factor SMAD2 0.0116 0.0246 0.0466
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0141 0.0304 1
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0041 0.007 0.0133
Schistosoma mansoni biogenic amine (5HT) receptor 0.0958 0.2226 0.2226
Plasmodium falciparum importin beta, putative 0.0031 0.0045 0.2916
Brugia malayi cytoplasmic intermediate filament protein 0.0031 0.0045 0.0085
Giardia lamblia DNA damage repair protein 0.0018 0.0016 0.0772
Echinococcus granulosus neuropeptide FF receptor 2 0.0958 0.2226 0.4225
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0022 0.0024 0.003
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.0011 0.0372
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0041 0.007 0.0133
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0014 0.0005 0.0156
Echinococcus granulosus neuropeptide Y receptor 0.0958 0.2226 0.4225
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0022 0.0024 0.0905
Mycobacterium tuberculosis Probable oxidoreductase 0.0119 0.0253 0.1078
Echinococcus granulosus S formylglutathione hydrolase 0.0035 0.0055 0.0104
Brugia malayi jmjC domain containing protein 0.0017 0.0012 0.0023
Brugia malayi steroid hormone receptor 0.0041 0.007 0.0133
Brugia malayi nuclear receptor NHR-88 0.0019 0.0019 0.0036
Onchocerca volvulus 0.0025 0.0031 0.0094
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0017 0.0014 0.0448
Brugia malayi ecdysone receptor 0.0019 0.0019 0.0036
Loa Loa (eye worm) hypothetical protein 0.0017 0.0014 0.0026
Mycobacterium ulcerans hypothetical protein 0.0035 0.0055 0.0231
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0112 0.0236 0.7774
Leishmania major DNA damage repair protein, putative 0.0018 0.0016 0.0519
Loa Loa (eye worm) hypothetical protein 0.0958 0.2226 0.4225
Loa Loa (eye worm) hypothetical protein 0.1408 0.3283 0.6231
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0017 0.0014 0.0017
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0019 0.0019 0.0024
Onchocerca volvulus 0.0958 0.2226 0.6779
Onchocerca volvulus 0.0025 0.0031 0.0094
Echinococcus granulosus tyrosine kinase 0.0012 0.0002 0.0003
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0013 0.0005 0.0045
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0958 0.2226 0.2812
Onchocerca volvulus 0.0094 0.0195 0.0593
Echinococcus multilocularis nmda type glutamate receptor 0.0012 0.0002 0.0002
Plasmodium vivax patched family protein, putative 0.0025 0.0031 0.2027
Brugia malayi Patched family protein 0.0025 0.0031 0.006
Loa Loa (eye worm) hypothetical protein 0.0958 0.2226 0.4225
Loa Loa (eye worm) beta-lactamase 0.0036 0.0057 0.0108
Onchocerca volvulus 0.1408 0.3283 1
Trypanosoma cruzi hypothetical protein, conserved 0.0018 0.0016 0.0519
Echinococcus granulosus GTP binding nuclear protein Ran 0.0023 0.0026 0.005
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0045 0.0079 0.0079
Loa Loa (eye worm) hypothetical protein 0.0958 0.2226 0.4225
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0025 0.0032 0.029
Echinococcus multilocularis allatostatin A receptor 0.0958 0.2226 0.2812
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0036 0.0057 0.0242
Schistosoma mansoni peroxidasin 0.1408 0.3283 0.3283
Echinococcus granulosus nmda type glutamate receptor 0.0012 0.0002 0.0003
Loa Loa (eye worm) hypothetical protein 0.0958 0.2226 0.4225
Echinococcus granulosus FTZ F1 alpha 0.0041 0.007 0.0133
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0038 0.0062 0.3975
Loa Loa (eye worm) hypothetical protein 0.0019 0.0019 0.0036
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0022 0.0024 0.0099
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0019 0.0019 0.0024
Loa Loa (eye worm) hypothetical protein 0.0022 0.0024 0.0046
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0041 0.007 0.0133
Brugia malayi Steroid receptor seven-up type 2 0.0041 0.007 0.0133
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0141 0.0304 0.2836
Mycobacterium ulcerans DNA polymerase IV 0.0059 0.0111 0.0469
Plasmodium falciparum ataxin-2 like protein, putative 0.0077 0.0155 1
Schistosoma mansoni hypothetical protein 0.0035 0.0055 0.0055
Loa Loa (eye worm) hypothetical protein 0.0958 0.2226 0.4225
Loa Loa (eye worm) hypothetical protein 0.0019 0.0019 0.0036
Trichomonas vaginalis alpha-glucosidase, putative 0.0013 0.0005 0.0039
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0958 0.2226 0.2812
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0041 0.007 0.0133
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.041 0.0937 1
Brugia malayi metabotropic glutamate receptor type 2 0.0064 0.0122 0.0232
Echinococcus multilocularis Polycystic kidney disease protein 0.0039 0.0065 0.0082
Echinococcus multilocularis tyrosine kinase 0.0012 0.0002 0.0002
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0017 0.0014 0.0122
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0119 0.0253 0.1078
Echinococcus granulosus expressed protein 0.0377 0.086 0.1633
Plasmodium vivax importin-beta 2, putative 0.0031 0.0045 0.2916
Trypanosoma cruzi DNA damage repair protein, putative 0.0018 0.0016 0.0519
Toxoplasma gondii ABC1 family protein 0.0036 0.0057 0.2164
Loa Loa (eye worm) neuropeptide F receptor 0.0958 0.2226 0.4225
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0074 0.0146 0.0619
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0022 0.0024 0.0784
Loa Loa (eye worm) hypothetical protein 0.0022 0.0024 0.0046
Echinococcus granulosus orexin receptor type 2 0.0958 0.2226 0.4225
Trichomonas vaginalis sucrase-isomaltase, putative 0.0036 0.0058 0.0539
Echinococcus granulosus serotonin receptor 0.0958 0.2226 0.4225
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0012 0.0002 0.0004
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0036 0.0057 0.0242
Loa Loa (eye worm) hypothetical protein 0.0019 0.0019 0.0035
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0014 0.0005 0.0156
Schistosoma mansoni ran 0.0023 0.0026 0.0026
Echinococcus granulosus expressed conserved protein 0.0385 0.0879 0.1668
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0011 0.0372
Treponema pallidum exodeoxyribonuclease (exoA) 0.0038 0.0062 0.0215
Plasmodium vivax acyl-CoA synthetase, putative 0.0055 0.0102 0.6594
Trichomonas vaginalis alpha-glucosidase, putative 0.0013 0.0005 0.0039
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0023 0.0026 0.005
Mycobacterium ulcerans aldehyde dehydrogenase 0.0065 0.0125 0.053
Onchocerca volvulus Serine\/threonine kinase homolog 0.0095 0.0198 0.06
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0059 0.0112 0.4261
Toxoplasma gondii patched family protein 0.0025 0.0031 0.1196
Schistosoma mansoni rab6-interacting 0.0039 0.0065 0.0065
Schistosoma mansoni jumonji/arid domain-containing protein 0.0064 0.0123 0.0123
Trypanosoma brucei inositol polyphosphate 1-phosphatase, putative 0.0012 0.0001 0.0018
Loa Loa (eye worm) hypothetical protein 0.0121 0.0258 0.0491
Schistosoma mansoni neuropeptide F-like receptor 0.0958 0.2226 0.2226
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0019 0.0019
Schistosoma mansoni biogenic amine receptor 0.0958 0.2226 0.2226
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0096 0.0198 0.185
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0011 0.0372
Plasmodium vivax phosphodiesterase gamma, putative 0.0017 0.0014 0.0877
Schistosoma mansoni aldehyde dehydrogenase 0.0065 0.0125 0.0125
Brugia malayi Patched related family protein 4 0.0025 0.0031 0.006
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0022 0.0024 0.0099
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0025 0.0032 0.029
Leishmania major alpha glucosidase II subunit, putative 0.0036 0.0058 0.1916
Mycobacterium ulcerans putative regulatory protein 0.0045 0.0078 0.0331
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0017 0.0013 0.0849
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0023 0.0026 0.0862
Onchocerca volvulus 0.0958 0.2226 0.6779
Loa Loa (eye worm) jmjC domain-containing protein 0.0064 0.0123 0.0234
Plasmodium falciparum thioredoxin reductase 0.0016 0.0011 0.0729
Echinococcus multilocularis neuropeptide receptor 0.0958 0.2226 0.2812
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0012 0.0002 0.0002
Brugia malayi AMP-binding enzyme family protein 0.0074 0.0146 0.0277
Brugia malayi Regulator of G protein signaling domain containing protein 0.0019 0.0019 0.0035
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0041 0.007 0.007
Loa Loa (eye worm) hypothetical protein 0.0019 0.0019 0.0036
Brugia malayi AMP-binding enzyme family protein 0.0022 0.0024 0.0045
Brugia malayi metabotropic glutamate receptor subtype 5a (mGluR5a), putative 0.0118 0.0251 0.0475
Schistosoma mansoni neuropeptide F-like receptor 0.0958 0.2226 0.2226
Brugia malayi jmjC domain containing protein 0.0063 0.012 0.0228
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0022 0.0024 0.0101
Loa Loa (eye worm) RGC/RGC protein kinase 0.0012 0.0002 0.0003
Loa Loa (eye worm) hypothetical protein 0.0958 0.2226 0.4225
Echinococcus multilocularis G-protein coupled receptor, putative 0.0958 0.2226 0.2812
Schistosoma mansoni hypothetical protein 0.0958 0.2226 0.2226
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0036 0.0058 0.0539
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0059 0.0111 0.021
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0057 0.0527
Schistosoma mansoni axis inhibition protein axin 0.0019 0.0019 0.0019
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0141 0.0304 0.2836
Loa Loa (eye worm) neuropeptide F receptor 0.0958 0.2226 0.4225
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0022 0.0024 0.0101
Trypanosoma cruzi inositol polyphosphate 1-phosphatase, putative 0.0012 0.0001 0.0018
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0141 0.0304 1
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0018 0.0015 0.0019
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0013 0.0005 0.0039
Schistosoma mansoni coup transcription factor 0.0041 0.007 0.007
Toxoplasma gondii GAF domain-containing protein 0.0045 0.0078 0.2978
Loa Loa (eye worm) hypothetical protein 0.0057 0.0107 0.0203
Onchocerca volvulus 0.0958 0.2226 0.6779
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0958 0.2226 0.2226
Brugia malayi Pre-SET motif family protein 0.0059 0.0112 0.0213
Onchocerca volvulus Protein ultraspiracle homolog 0.0041 0.007 0.0212
Schistosoma mansoni hypothetical protein 0.0289 0.0653 0.0653
Loa Loa (eye worm) hypothetical protein 0.0041 0.007 0.0133
Echinococcus granulosus lamin dm0 0.0057 0.0107 0.0203
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0141 0.0304 0.2836
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.006
Echinococcus granulosus importin subunit beta 1 0.0031 0.0045 0.0086
Brugia malayi glutathione reductase 0.0047 0.0084 0.0159
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0041 0.007 0.0212
Echinococcus granulosus allatostatin A receptor 0.0958 0.2226 0.4225
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0022 0.0024 0.0099
Loa Loa (eye worm) patched family protein 0.0025 0.0031 0.006
Schistosoma mansoni nuclear hormone receptor 0.0041 0.007 0.007
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0024 0.0099
Loa Loa (eye worm) hypothetical protein 0.0041 0.007 0.0133
Loa Loa (eye worm) hypothetical protein 0.0039 0.0065 0.0123
Loa Loa (eye worm) hypothetical protein 0.1408 0.3283 0.6231
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.01 0.0208 0.0884
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0055 0.0102 0.0435
Echinococcus granulosus tumor protein p63 0.0335 0.0761 0.1445
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.002 0.0019 0.0037
Trypanosoma cruzi hypothetical protein, conserved 0.0017 0.0014 0.0448
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0041 0.007 0.0133
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0228 0.0509 0.2164
Loa Loa (eye worm) hypothetical protein 0.0306 0.0691 0.1312
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0017 0.0014 0.0518
Toxoplasma gondii HEAT repeat-containing protein 0.0031 0.0045 0.1721
Loa Loa (eye worm) G-protein coupled receptor 0.0958 0.2226 0.4225
Echinococcus multilocularis thioredoxin glutathione reductase 0.0047 0.0084 0.0106
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0017 0.0014 0.0877
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0076 0.0151 0.019
Echinococcus granulosus geminin 0.012 0.0255 0.0483
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0107 0.0225 0.0958
Mycobacterium leprae conserved hypothetical protein 0.0045 0.0078 0.0331
Schistosoma mansoni alpha glucosidase 0.0036 0.0058 0.0058
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0958 0.2226 0.2226
Onchocerca volvulus 0.0958 0.2226 0.6779
Schistosoma mansoni blooms syndrome DNA helicase 0.002 0.002 0.002
Mycobacterium tuberculosis Probable dehydrogenase 0.0107 0.0225 0.0958
Entamoeba histolytica hypothetical protein 0.0025 0.0032 0.0331
Schistosoma mansoni lipoxygenase 0.011 0.023 0.023
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0022 0.0024 0.0101
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0041 0.007 0.0133
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.006
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0057 0.0106 0.0201
Brugia malayi Regulator of G protein signaling domain containing protein 0.0019 0.0019 0.0035
Trypanosoma cruzi polo-like protein kinase, putative 0.0095 0.0198 0.6507
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0052 0.0095 0.0405
Brugia malayi Doublecortin family protein 0.0039 0.0065 0.0123
Schistosoma mansoni steroid hormone receptor ad4bp 0.0041 0.007 0.007
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0017 0.0014 0.0026
Schistosoma mansoni DNA polymerase eta 0.0085 0.0174 0.0174
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0024 0.0099
Plasmodium falciparum thioredoxin reductase 0.0047 0.0084 0.5387
Brugia malayi jmjC domain containing protein 0.0017 0.0012 0.0023
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0022 0.0024 0.0045
Brugia malayi Copper type II ascorbate-dependent monooxygenase, C-terminal domain containing protein 0.2252 0.5269 1
Trichomonas vaginalis DNA polymerase eta, putative 0.0059 0.0111 0.1032
Brugia malayi Intermediate filament tail domain containing protein 0.0057 0.0107 0.0203
Echinococcus granulosus neuropeptide s receptor 0.0958 0.2226 0.4225
Trypanosoma cruzi PAB1-binding protein , putative 0.0077 0.0155 0.5111
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0958 0.2226 0.2226
Loa Loa (eye worm) hypothetical protein 0.0022 0.0024 0.0046
Brugia malayi Pre-SET motif family protein 0.041 0.0936 0.1777
Mycobacterium tuberculosis Two component sensor histidine kinase DevS 0.0045 0.0078 0.0333
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0014 0.0005 0.0156
Brugia malayi follicle stimulating hormone receptor 0.0958 0.2226 0.4225
Loa Loa (eye worm) hypothetical protein 0.0958 0.2226 0.4225
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0016 0.0011 0.0046
Trypanosoma brucei DNA polymerase kappa, putative 0.0059 0.0111 0.3649
Loa Loa (eye worm) hypothetical protein 0.0017 0.0014 0.0026
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0041 0.007 0.0088
Brugia malayi Nuclear hormone receptor E75 0.0019 0.0019 0.0036
Loa Loa (eye worm) hypothetical protein 0.0958 0.2226 0.4225
Trichomonas vaginalis importin beta-1, putative 0.0025 0.0032 0.029
Echinococcus multilocularis g protein coupled receptor 0.0958 0.2226 0.2812
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0135 0.0291 0.0368
Loa Loa (eye worm) G-protein coupled receptor 0.0958 0.2226 0.4225
Echinococcus multilocularis snurportin 1 0.0328 0.0744 0.0941
Brugia malayi hypothetical protein 0.0025 0.0031 0.006
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0958 0.2226 0.2812
Trypanosoma cruzi myo-inositol-1 phosphatase, putative 0.0012 0.0001 0.0018
Schistosoma mansoni neuropeptide receptor 0.0958 0.2226 0.2226
Trichomonas vaginalis DNA helicase recq, putative 0.0014 0.0005 0.0039
Echinococcus granulosus regulator of G protein signaling 3 0.0019 0.0019 0.0035
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0022 0.0024 0.0045
Brugia malayi PXA domain containing protein 0.0019 0.0019 0.0035
Loa Loa (eye worm) hypothetical protein 0.0159 0.0347 0.0659
Echinococcus granulosus somatostatin receptor 0.0958 0.2226 0.4225
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.0198 0.1843
Echinococcus granulosus arachidonate 5 lipoxygenase 0.011 0.023 0.0437
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0023 0.0026 0.0862
Echinococcus granulosus rhodopsin orphan GPCR 0.0958 0.2226 0.4225
Loa Loa (eye worm) animal heme peroxidase 0.1408 0.3283 0.6231
Echinococcus granulosus rhodopsin orphan GPCR 0.0958 0.2226 0.4225
Leishmania major extracellular receptor, putative 0.0012 0.0002 0.0059
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0112 0.0236 0.7774
Loa Loa (eye worm) hypothetical protein 0.0026 0.0035 0.0067
Mycobacterium leprae Secreted antigen 85A FbpA (mycolyl transferase 85A) (fibronectin-binding protein A) (antigen 85 complex A) 0.0035 0.0055 0.0231
Loa Loa (eye worm) hypothetical protein 0.0958 0.2226 0.4225
Onchocerca volvulus 0.0958 0.2226 0.6779
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0022 0.0024 0.0784
Loa Loa (eye worm) hypothetical protein 0.0958 0.2226 0.4225
Trichomonas vaginalis ran, putative 0.0023 0.0026 0.024
Onchocerca volvulus 0.0049 0.0088 0.0268
Onchocerca volvulus 0.0958 0.2226 0.6779
Loa Loa (eye worm) hypothetical protein 0.0958 0.2226 0.4225
Brugia malayi putative neuropeptide receptor NPR1 0.0958 0.2226 0.4225
Brugia malayi jmjC domain containing protein 0.0017 0.0012 0.0023
Loa Loa (eye worm) hypothetical protein 0.0017 0.0012 0.0023
Onchocerca volvulus Neuropeptide F receptor homolog 0.0958 0.2226 0.6779
Schistosoma mansoni DNA polymerase IV / kappa 0.0018 0.0016 0.0016
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0017 0.0012 0.0467
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0022 0.0024 0.0784
Brugia malayi Inositol monophosphatase family protein 0.0012 0.0001 0.0001
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0016 0.0011 0.0021
Brugia malayi conserved hypotetical protein 0.0019 0.0019 0.0036
Schistosoma mansoni myosin xvIII 0.0958 0.2226 0.2226
Loa Loa (eye worm) hypothetical protein 0.0036 0.0057 0.0108
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0022 0.0024 0.0099
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0022 0.0024 0.0046
Onchocerca volvulus 0.0036 0.0057 0.0172
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0958 0.2226 0.4225
Echinococcus multilocularis serotonin receptor 0.0958 0.2226 0.2812
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.006
Echinococcus granulosus peptidyl glycine alpha amidating monooxygenase 0.2252 0.5269 1
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0014 0.0122
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0019 0.0019 0.0035
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0036 0.0057 0.0108
Schistosoma mansoni amine GPCR 0.0958 0.2226 0.2226
Loa Loa (eye worm) hypothetical protein 0.0024 0.003 0.0056
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0017 0.0012 0.0405
Brugia malayi DOMON domain containing protein 0.0431 0.0987 0.1873
Mycobacterium ulcerans acyl-CoA synthetase 0.0074 0.0146 0.0619
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0019 0.0019
Onchocerca volvulus Peroxidase homolog 0.1408 0.3283 1
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0958 0.2226 0.2812
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0416 0.0952 0.0952
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0016 0.0011 0.0372
Trypanosoma brucei DNA polymerase IV, putative 0.0059 0.0111 0.3649
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0074 0.0146 0.0619
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0019 0.0019 0.0023
Onchocerca volvulus Huntingtin homolog 0.0121 0.0258 0.0786
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0017 0.0014 0.0518
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0017 0.0014 0.0518
Echinococcus multilocularis S formylglutathione hydrolase 0.0035 0.0055 0.0069
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0038 0.0062 0.0215
Loa Loa (eye worm) hypothetical protein 0.0022 0.0024 0.0046
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0958 0.2226 0.2226
Schistosoma mansoni hypothetical protein 0.0012 0.0001 0.0001
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0019 0.0019 0.0036
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0958 0.2226 0.2226
Schistosoma mansoni amine GPCR 0.0958 0.2226 0.2226
Schistosoma mansoni inositol monophosphatase 0.0112 0.0236 0.0236
Onchocerca volvulus 0.0022 0.0024 0.0071
Brugia malayi Patched family protein 0.0025 0.0031 0.006
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0052 0.0095 0.0405
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0017 0.0014 0.0518
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0017 0.0014 0.0122
Echinococcus multilocularis beta adrenergic receptor kinase 0.002 0.0019 0.0024
Echinococcus multilocularis orexin receptor type 2 0.0958 0.2226 0.2812
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0058 0.1916
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0035 0.0055 0.0069
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0022 0.0024 0.0101
Brugia malayi Inositol monophosphatase family protein 0.0012 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0019 0.0019 0.0036
Brugia malayi protein C24B5.3 0.0025 0.0031 0.006
Echinococcus multilocularis high affinity cgmp specific 3' 5' cyclic 0.0017 0.0014 0.0017
Trypanosoma cruzi hypothetical protein, conserved 0.0017 0.0014 0.0448
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0017 0.0014 0.0448
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0022 0.0024 0.0101
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0016 0.0011 0.0014
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0019 0.0168
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0023 0.0026 0.005
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0041 0.007 0.007
Schistosoma mansoni alpha-glucosidase 0.0141 0.0303 0.0303
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.006
Brugia malayi GnHR receptor homolog 0.0958 0.2226 0.4225
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0135 0.0291 0.0552
Brugia malayi nuclear receptor NHR-67 0.0019 0.0019 0.0036
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0017 0.0014 0.0518
Echinococcus granulosus beta-adrenergic receptor kinase 0.002 0.0019 0.0037
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0062 0.0119 0.1108
Echinococcus multilocularis tumor protein p63 0.0335 0.0761 0.0962
Plasmodium vivax thioredoxin reductase, putative 0.0047 0.0084 0.5387
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0176 0.0387 0.0734
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0022 0.0024 0.0099
Onchocerca volvulus 0.0466 0.1069 0.3255
Loa Loa (eye worm) hypothetical protein 0.0074 0.0146 0.0277
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.006
Loa Loa (eye worm) blistered cuticle protein 3 0.1408 0.3283 0.6231
Trypanosoma brucei trypanothione reductase 0.0047 0.0084 0.2753
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0017 0.0014 0.0518
Loa Loa (eye worm) hypothetical protein 0.0958 0.2226 0.4225
Echinococcus granulosus neuropeptide Y receptor 0.0958 0.2226 0.4225
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0958 0.2226 0.4225
Loa Loa (eye worm) hypothetical protein 0.0019 0.0019 0.0035
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.006
Schistosoma mansoni nuclear receptor 0.0019 0.0019 0.0019
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.0062 0.0119 0.0119
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0958 0.2226 0.2226
Loa Loa (eye worm) hypothetical protein 0.0958 0.2226 0.4225
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0003
Loa Loa (eye worm) hypothetical protein 0.0958 0.2226 0.4225
Loa Loa (eye worm) hypothetical protein 0.0958 0.2226 0.4225
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0022 0.0024 0.0024
Schistosoma mansoni patched 1 0.0176 0.0387 0.0387
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0065 0.0125 0.0158
Schistosoma mansoni hypothetical protein 0.0958 0.2226 0.2226
Brugia malayi nuclear hormone receptor family member odr-7 0.0019 0.0019 0.0036
Echinococcus multilocularis beta LACTamase domain containing family member 0.0036 0.0057 0.0072
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0958 0.2226 0.2226
Mycobacterium tuberculosis Conserved protein 0.0036 0.0057 0.0242
Onchocerca volvulus 0.0019 0.0019 0.0055
Loa Loa (eye worm) hypothetical protein 0.0958 0.2226 0.4225
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0038 0.0062 0.2032
Schistosoma mansoni kinase 0.0049 0.0087 0.0087
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0112 0.0236 0.2203
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0038 0.0062 0.2032
Schistosoma mansoni hypothetical protein 0.012 0.0255 0.0255
Brugia malayi DOMON domain containing protein 0.0431 0.0987 0.1873
Brugia malayi photoreceptor-specific nuclear receptor 0.0041 0.007 0.0133
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0012 0.0001 0.0002
Echinococcus granulosus rhodopsin orphan GPCR 0.0958 0.2226 0.4225
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0017 0.0014 0.0518
Trypanosoma brucei DNA polymerase kappa, putative 0.0018 0.0016 0.0519
Schistosoma mansoni nuclear receptor 0.0019 0.0019 0.0019
Schistosoma mansoni cpg binding protein 0.002 0.0021 0.0021
Echinococcus multilocularis musashi 0.0057 0.0107 0.0135
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0022 0.0024 0.1534
Trypanosoma brucei cAMP phosphodiesterase A, putative 0.0017 0.0014 0.0448
Loa Loa (eye worm) hypothetical protein 0.0958 0.2226 0.4225
Trypanosoma cruzi DNA polymerase kappa, putative 0.0059 0.0111 0.3649
Mycobacterium tuberculosis Monophosphatase CysQ 0.0012 0.0001 0.0002
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0017 0.0014 0.0877
Echinococcus multilocularis regulator of G protein signaling 3 0.0019 0.0019 0.0023
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0022 0.0024 0.0248
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0041 0.007 0.0133
Schistosoma mansoni z-protein (S1r protein) 0.0019 0.0019 0.0019
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.0062 0.0119 0.015
Loa Loa (eye worm) doublecortin family protein 0.0039 0.0065 0.0123
Loa Loa (eye worm) glutathione reductase 0.0047 0.0084 0.0159
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0017 0.0014 0.0122
Loa Loa (eye worm) hypothetical protein 0.1408 0.3283 0.6231
Toxoplasma gondii hypothetical protein 0.0045 0.0078 0.2978
Trypanosoma brucei chrX additional, unordered contigs 0.0018 0.0016 0.0519
Mycobacterium ulcerans error-prone DNA polymerase 0.1012 0.2352 1
Echinococcus multilocularis phd:f box containing protein 0.0017 0.0012 0.0016
Leishmania major cAMP phosphodiesterase A, putative;with=GeneDB:LinJ18_V3.1100 0.0017 0.0014 0.0448
Echinococcus granulosus neuropeptide receptor A26 0.0958 0.2226 0.4225
Schistosoma mansoni hypothetical protein 0.017 0.0372 0.0372
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0057 0.0527
Trypanosoma cruzi hypothetical protein, conserved 0.0017 0.0014 0.0448
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.01 0.0208 0.0886
Loa Loa (eye worm) hypothetical protein 0.0958 0.2226 0.4225
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0017 0.0014 0.0518
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0041 0.007 0.0088
Echinococcus granulosus high affinity cAMP specific 3'5' cyclic 0.0017 0.0014 0.0026
Echinococcus multilocularis sterol regulatory element binding protein 0.0176 0.0387 0.0489
Brugia malayi G protein-coupled receptor F59B2.13 0.0958 0.2226 0.4225
Trichomonas vaginalis mercuric reductase, putative 0.0016 0.0011 0.0101
Loa Loa (eye worm) hypothetical protein 0.041 0.0937 0.1779
Echinococcus multilocularis neuropeptide receptor 0.0958 0.2226 0.2812
Loa Loa (eye worm) hypothetical protein 0.0958 0.2226 0.4225
Brugia malayi AMP-binding enzyme family protein 0.0022 0.0024 0.0045
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0016 0.0011 0.0372
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0059 0.0111 0.014
Brugia malayi hypothetical protein 0.0958 0.2226 0.4225
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0017 0.0014 0.0122
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0958 0.2226 0.4225
Brugia malayi hypothetical protein 0.0077 0.0155 0.0294
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.0011 0.0372
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0135 0.0291 0.0552
Schistosoma mansoni jumonji/arid domain-containing protein 0.0064 0.0123 0.0123
Brugia malayi nuclear receptor RXR 0.0022 0.0024 0.0046
Loa Loa (eye worm) hypothetical protein 0.0041 0.007 0.0133
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0055 0.0102 0.0433
Onchocerca volvulus Protein patched homolog 0.0025 0.0031 0.0094
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0958 0.2226 0.2226
Trichomonas vaginalis calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0017 0.0014 0.0122
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0017 0.0014 0.0518
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0017 0.0014 0.0026
Echinococcus granulosus lysosomal alpha glucosidase 0.0163 0.0357 0.0677
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0041 0.007 0.0133
Trypanosoma brucei DNA polymerase kappa, putative 0.0059 0.0111 0.3649
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0068 0.224
Echinococcus multilocularis thyroid hormone receptor alpha 0.0041 0.007 0.0088
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0141 0.0304 1
Echinococcus granulosus atrial natriuretic peptide receptor 0.0012 0.0002 0.0003
Brugia malayi CHE-14 protein 0.0176 0.0387 0.0734
Brugia malayi hypothetical protein 0.0958 0.2226 0.4225
Onchocerca volvulus Bile acid receptor homolog 0.0041 0.007 0.0212
Leishmania major DNA polymerase kappa, putative 0.0059 0.0111 0.3649
Loa Loa (eye worm) hypothetical protein 0.2252 0.5269 1
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0019 0.0019
Echinococcus multilocularis dna polymerase eta 0.0085 0.0174 0.022
Schistosoma mansoni peptidyl-glycine monooxygenase 0.2252 0.5269 0.5269
Brugia malayi intermediate filament protein 0.0057 0.0107 0.0203
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0019 0.0019
Loa Loa (eye worm) metabotropic glutamate receptor 8 0.0012 0.0002 0.0003
Loa Loa (eye worm) hypothetical protein 0.0036 0.0057 0.0108
Loa Loa (eye worm) hypothetical protein 0.0074 0.0146 0.0277
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0019 0.0168
Echinococcus multilocularis microtubule associated protein 2 0.0488 0.112 0.1415
Schistosoma mansoni hypothetical protein 0.0021 0.0023 0.0023
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0141 0.0304 0.2836
Leishmania major GTP-binding protein, putative 0.0023 0.0026 0.0862
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0038 0.0062 0.026
Mycobacterium ulcerans aldehyde dehydrogenase 0.0065 0.0125 0.053
Mycobacterium tuberculosis Conserved hypothetical protein 0.0191 0.0423 0.1798
Brugia malayi jmjC domain containing protein 0.0064 0.0123 0.0234
Loa Loa (eye worm) DOMON domain-containing protein 0.0431 0.0987 0.1873
Echinococcus granulosus axis inhibition protein axin 0.0019 0.0019 0.0035
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0018 0.0015 0.0028
Brugia malayi Thioredoxin reductase 0.0047 0.0084 0.0159
Schistosoma mansoni calcium/calmodulin-dependent 35-cyclic nucleotide phosphodiesterase 0.0017 0.0014 0.0014
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.0062 0.0119 0.0226
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0017 0.0014 0.0026
Schistosoma mansoni hypothetical protein 0.0328 0.0744 0.0744
Schistosoma mansoni opsin-like receptor 0.0958 0.2226 0.2226
Loa Loa (eye worm) PXA domain-containing protein 0.0019 0.0019 0.0035
Loa Loa (eye worm) hypothetical protein 0.0216 0.048 0.0911
Brugia malayi hypothetical protein 0.0958 0.2226 0.4225
Leishmania major hypothetical protein, conserved 0.0017 0.0012 0.0405
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0019 0.0168
Loa Loa (eye worm) hypothetical protein 0.1408 0.3283 0.6231
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0003
Trichomonas vaginalis inositol monophosphatase, putative 0.0112 0.0236 0.2203
Trypanosoma brucei DNA polymerase kappa, putative 0.0059 0.0111 0.3649
Echinococcus granulosus high affinity cgmp specific 3' 5' cyclic 0.0017 0.0014 0.0026
Echinococcus granulosus sterol regulatory element binding protein 0.0176 0.0387 0.0734
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0958 0.2226 0.2812
Schistosoma mansoni phd/f-box containing protein 0.0017 0.0012 0.0012
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0017 0.0014 0.0518
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0141 0.0304 0.2836
Loa Loa (eye worm) oxidoreductase 0.0022 0.0024 0.0045
Echinococcus multilocularis geminin 0.012 0.0255 0.0322
Onchocerca volvulus Poor gastrulation protein homolog 0.0021 0.0023 0.0068
Schistosoma mansoni hypothetical protein 0.0039 0.0065 0.0065
Echinococcus multilocularis neuropeptide s receptor 0.0958 0.2226 0.2812
Schistosoma mansoni polycystin 1-related 0.0039 0.0065 0.0065
Brugia malayi Patched family protein 0.0025 0.0031 0.006
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0141 0.0304 0.2836
Brugia malayi A-kinase anchor protein 10, precursor 0.0019 0.0019 0.0035
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0024 0.0099
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0041 0.007 0.0133
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0027 0.0038 0.0048
Brugia malayi hypothetical protein 0.0958 0.2226 0.4225
Loa Loa (eye worm) hypothetical protein 0.0022 0.0024 0.0045
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0019 0.0019 0.0036
Trypanosoma cruzi DNA polymerase eta, putative 0.0045 0.0079 0.2597
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.006
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0057 0.0527
Echinococcus multilocularis lipoxygenase domain containing protein 0.0039 0.0065 0.0082
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0017 0.0014 0.0518
Onchocerca volvulus 0.0025 0.0031 0.0094
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.006
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0017 0.0014 0.0122
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0016 0.0011 0.0011
Onchocerca volvulus 0.0074 0.0146 0.0443
Echinococcus multilocularis expressed protein 0.0377 0.086 0.1087
Loa Loa (eye worm) hypothetical protein 0.0958 0.2226 0.4225
Echinococcus multilocularis rhodopsin orphan GPCR 0.0958 0.2226 0.2812
Brugia malayi Bloom's syndrome protein homolog 0.0025 0.0032 0.0062
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0141 0.0304 0.2836
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0022 0.0024 0.0045
Entamoeba histolytica acyl-coA synthetase, putative 0.0074 0.0146 0.1554
Plasmodium vivax hypothetical protein, conserved 0.0045 0.0078 0.5046
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0027 0.0038 0.0071
Schistosoma mansoni thyroid hormone receptor 0.0041 0.007 0.007
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0016 0.0011 0.0729
Onchocerca volvulus 0.0025 0.0031 0.0094
Mycobacterium ulcerans hypothetical protein 0.0036 0.0057 0.024
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0036 0.0058 0.2213
Brugia malayi nuclear hormone receptor 0.0041 0.007 0.0133
Schistosoma mansoni opsin-like receptor 0.0958 0.2226 0.2226
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.006
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0065 0.0125 0.4123
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0035 0.0056 0.0106
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0141 0.0304 0.2836
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0011 0.0372
Mycobacterium ulcerans hypothetical protein 0.0074 0.0146 0.0619
Brugia malayi nuclear hormone receptor 0.0019 0.0019 0.0036
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0003
Loa Loa (eye worm) hypothetical protein 0.0127 0.0272 0.0517
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0112 0.0236 0.2203
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0017 0.0014 0.0877
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0163 0.0357 0.0677
Entamoeba histolytica hypothetical protein 0.0076 0.0151 0.1602
Loa Loa (eye worm) CXXC zinc finger family protein 0.002 0.0021 0.0039
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.0141 0.0304 0.0304
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0063 0.012 0.0228
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0017 0.0014 0.0877
Mycobacterium ulcerans acetyl-CoA synthetase 0.0022 0.0024 0.0099
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0013 0.0005 0.0013
Plasmodium vivax DNA repair protein REV1, putative 0.0018 0.0016 0.1015
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0022 0.0025 0.1624
Echinococcus multilocularis regulator of G protein signaling 0.0019 0.0019 0.0023
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0958 0.2226 0.2226
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0135 0.0291 0.0552
Toxoplasma gondii hypothetical protein 0.0012 0.0001 0.002
Brugia malayi hypothetical protein 0.0022 0.0024 0.0046
Echinococcus multilocularis sex peptide receptor 0.0958 0.2226 0.2812
Loa Loa (eye worm) steroid hormone receptor 0.0041 0.007 0.0133
Echinococcus multilocularis lamin dm0 0.0057 0.0107 0.0135
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0958 0.2226 0.2226
Wolbachia endosymbiont of Brugia malayi DNA polymerase III alpha subunit 0.1012 0.2352 1
Echinococcus granulosus g protein coupled receptor 0.0958 0.2226 0.4225
Loa Loa (eye worm) melatonin receptor type 1A 0.0958 0.2226 0.4225
Schistosoma mansoni peptidylglycine monooxygenase 0.2252 0.5269 0.5269
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0041 0.007 0.0133
Entamoeba histolytica endo-1,4-beta-xylanase, putative 0.0035 0.0055 0.0581
Loa Loa (eye worm) hypothetical protein 0.0049 0.0088 0.0168
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0141 0.0304 0.2836
Echinococcus granulosus tm gpcr rhodopsin 0.0958 0.2226 0.4225
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0041 0.007 0.007
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0958 0.2226 0.2226
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0035 0.0055 0.0104
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.006
Schistosoma mansoni hypothetical protein 0.017 0.0372 0.0372
Loa Loa (eye worm) hypothetical protein 0.0085 0.0174 0.033
Brugia malayi hypothetical protein 0.0025 0.0031 0.006
Echinococcus multilocularis atrial natriuretic peptide receptor 0.0012 0.0002 0.0002
Mycobacterium tuberculosis Secreted antigen 85-a FbpA (mycolyl transferase 85A) (fibronectin-binding protein A) (antigen 85 complex A) 0.0035 0.0055 0.0234
Echinococcus granulosus lamin 0.0057 0.0107 0.0203
Trichomonas vaginalis antibiotic synthetase, putative 0.0022 0.0024 0.0218
Brugia malayi ImpB/MucB/SamB family protein 0.0085 0.0174 0.033
Plasmodium falciparum GAF domain-related protein, putative 0.0045 0.0078 0.5046
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0017 0.0014 0.0014
Echinococcus multilocularis axis inhibition protein axin 0.0019 0.0019 0.0023
Entamoeba histolytica recQ family helicase, putative 0.0014 0.0005 0.0045
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.0198 0.1843
Loa Loa (eye worm) hypothetical protein 0.0958 0.2226 0.4225
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.006
Brugia malayi Animal haem peroxidase family protein 0.1408 0.3283 0.6231
Brugia malayi G-protein coupled receptor 0.0958 0.2226 0.4225
Trypanosoma cruzi PAB1-binding protein , putative 0.0077 0.0155 0.5111
Schistosoma mansoni growth hormone secretagogue receptor 0.0958 0.2226 0.2226
Brugia malayi Patched family protein 0.0025 0.0031 0.006
Echinococcus multilocularis protein dispatched 1 0.0201 0.0445 0.0563
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0024 0.0099
Echinococcus granulosus neuropeptide receptor 0.0958 0.2226 0.4225
Echinococcus multilocularis regulator of G protein signaling 7 0.0019 0.0019 0.0023
Giardia lamblia DINP protein human, muc B family 0.0059 0.0111 0.5596
Loa Loa (eye worm) RecQ helicase 0.0025 0.0032 0.0062
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0019 0.0019 0.0024
Echinococcus multilocularis rhodopsin orphan GPCR 0.0958 0.2226 0.2812
Loa Loa (eye worm) jmjC domain-containing protein 0.0017 0.0012 0.0023
Brugia malayi Dopamine receptor protein 1 0.0958 0.2226 0.4225
Mycobacterium ulcerans hypothetical protein 0.0035 0.0055 0.0231
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0112 0.0236 0.7774
Brugia malayi Patched family protein 0.0025 0.0031 0.006
Brugia malayi AMP-binding enzyme family protein 0.0022 0.0024 0.0045
Trypanosoma cruzi cAMP-specific phosphodiesterase, putative 0.0017 0.0014 0.0448
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0041 0.007 0.0133
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0074 0.0146 0.0619
Loa Loa (eye worm) hypothetical protein 0.0036 0.0057 0.0108
Brugia malayi Glycosyl hydrolases family 31 protein 0.0013 0.0005 0.0009
Loa Loa (eye worm) hypothetical protein 0.0958 0.2226 0.4225
Mycobacterium ulcerans aldehyde dehydrogenase 0.0065 0.0125 0.053
Trichomonas vaginalis ap endonuclease, putative 0.0038 0.0062 0.0572
Brugia malayi hypothetical protein 0.0022 0.0024 0.0046
Giardia lamblia NADH oxidase lateral transfer candidate 0.0016 0.0011 0.0547
Onchocerca volvulus Peroxidasin homolog 0.1408 0.3283 1
Echinococcus multilocularis metabotropic glutamate receptor 5 0.016 0.035 0.0442
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0019 0.0019 0.0019
Echinococcus granulosus lipoxygenase domain containing protein 0.0039 0.0065 0.0123
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0022 0.0024 0.0099
Mycobacterium ulcerans hypothetical protein 0.0191 0.0423 0.1796
Echinococcus granulosus Niemann Pick C1 protein 0.0586 0.1351 0.2564
Schistosoma mansoni tyrosine kinase 0.0012 0.0002 0.0002
Echinococcus granulosus phd:f box containing protein 0.0017 0.0012 0.0023
Schistosoma mansoni alpha-glucosidase 0.0141 0.0303 0.0303
Loa Loa (eye worm) hypothetical protein 0.1408 0.3283 0.6231
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0022 0.0024 0.0099
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0038 0.0062 0.3975
Brugia malayi hypothetical protein 0.0025 0.0031 0.006
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.3378 0.7914 1
Trypanosoma brucei inositol-1(or 4)-monophosphatase, putative 0.0012 0.0001 0.0018
Loa Loa (eye worm) hypothetical protein 0.0958 0.2226 0.4225
Plasmodium vivax ataxin-2 like protein, putative 0.0077 0.0155 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0041 0.007 0.0133
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0023 0.0026 0.1686
Echinococcus multilocularis lipoxygenase domain containing protein 0.0039 0.0065 0.0082
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0036 0.0057 0.0242
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0022 0.0024 0.0099
Trichomonas vaginalis conserved hypothetical protein 0.0123 0.0263 0.2455
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0036 0.0058 0.011
Trypanosoma cruzi trypanothione reductase, putative 0.0047 0.0084 0.2753
Echinococcus granulosus rhodopsin orphan GPCR 0.0958 0.2226 0.4225
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0041 0.007 0.0133
Plasmodium vivax hypothetical protein, conserved 0.0036 0.0057 0.3667
Mycobacterium tuberculosis Conserved hypothetical protein 0.0059 0.0111 0.0471
Brugia malayi Serotonin receptor 0.0958 0.2226 0.4225
Brugia malayi Niemann-Pick C1 protein precursor 0.041 0.0937 0.1779
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.006
Brugia malayi hypothetical protein 0.0039 0.0065 0.0123
Trypanosoma brucei DNA polymerase kappa, putative 0.0059 0.0111 0.3649
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0038 0.0062 0.0117
Loa Loa (eye worm) glutamate receptor 0.0051 0.0093 0.0177
Mycobacterium leprae PROBABLE DNA POLYMERASE III (ALPHA CHAIN) DNAE1 (DNA NUCLEOTIDYLTRANSFERASE) 0.1012 0.2352 1
Trypanosoma brucei importin beta-1 subunit, putative 0.0031 0.0045 0.149
Schistosoma mansoni hypothetical protein 0.0958 0.2226 0.2226
Loa Loa (eye worm) esterase D 0.0035 0.0055 0.0104
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0095 0.0198 0.0375
Onchocerca volvulus 0.0025 0.0031 0.0094
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0107 0.0225 0.0958
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0022 0.0024 0.0784
Trypanosoma cruzi hypothetical protein, conserved 0.0018 0.0016 0.0519
Onchocerca volvulus 0.0022 0.0024 0.0071
Trichomonas vaginalis esterase, putative 0.0036 0.0057 0.0527
Loa Loa (eye worm) hypothetical protein 0.0021 0.0023 0.0043
Loa Loa (eye worm) hypothetical protein 0.0958 0.2226 0.4225
Brugia malayi hypothetical protein 0.0958 0.2226 0.4225
Toxoplasma gondii propionate-CoA ligase 0.0022 0.0024 0.0905
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0022 0.0024 0.0031
Onchocerca volvulus 0.0958 0.2226 0.6779
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0014 0.0122
Brugia malayi CXXC zinc finger family protein 0.002 0.0021 0.0039
Loa Loa (eye worm) hypothetical protein 0.0958 0.2226 0.4225
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0019 0.0019 0.0019
Echinococcus multilocularis rhodopsin orphan GPCR 0.0958 0.2226 0.2812
Echinococcus multilocularis RUN 0.0039 0.0065 0.0082
Leishmania major myo-inositol-1 phosphatase, putative 0.0012 0.0001 0.0018
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0059 0.0112 0.0112
Loa Loa (eye worm) hypothetical protein 0.0019 0.0019 0.0036
Loa Loa (eye worm) hypothetical protein 0.0958 0.2226 0.4225
Loa Loa (eye worm) hypothetical protein 0.0041 0.007 0.0133
Onchocerca volvulus Metabotropic glutamate receptor homolog 0.0021 0.0023 0.0068
Echinococcus multilocularis importin subunit beta 1 0.0031 0.0045 0.0057
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0958 0.2226 0.2812
Trichomonas vaginalis maltase-glucoamylase, putative 0.0036 0.0058 0.0539
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0047 0.0084 0.0355
Onchocerca volvulus 0.0041 0.007 0.0212
Echinococcus multilocularis Niemann Pick C1 protein 0.041 0.0937 0.1184
Trypanosoma cruzi importin beta-1 subunit, putative 0.0025 0.0032 0.104
Echinococcus multilocularis fmrfamide receptor 0.0958 0.2226 0.2812
Trypanosoma cruzi polo-like protein kinase, putative 0.0095 0.0198 0.6507
Echinococcus multilocularis neuropeptides capa receptor 0.0958 0.2226 0.2812
Brugia malayi Blistered cuticle protein 3 0.1408 0.3283 0.6231
Loa Loa (eye worm) hypothetical protein 0.0033 0.0052 0.0098
Loa Loa (eye worm) hypothetical protein 0.0958 0.2226 0.4225
Leishmania major acetyl-CoA synthetase, putative 0.0022 0.0024 0.0784
Onchocerca volvulus 0.0019 0.0019 0.0055
Loa Loa (eye worm) hypothetical protein 0.0036 0.0057 0.0108

Activities

Activity type Activity value Assay description Source Reference
Ki (binding) = 0.077 nM Ability to inhibit [125I]-ET-3 binding to the Endothelin B receptor from porcine lung membranes was evaluated ChEMBL. No reference
Ki (binding) = 0.077 nM Ability to inhibit [125I]-ET-3 binding to the Endothelin B receptor from porcine lung membranes was evaluated ChEMBL. No reference
Ki (binding) = 620 nM Ability to inhibit [125I]-ET-1 binding to the Endothelin A receptor from porcine lung membranes was evaluated ChEMBL. No reference
Ki (binding) = 620 nM Ability to inhibit [125I]-ET-1 binding to the Endothelin A receptor from porcine lung membranes was evaluated ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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