Detailed information for compound 422601

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 519.677 | Formula: C27H45N5O5
  • H donors: 4 H acceptors: 5 LogP: 3.03 Rotable bonds: 14
    Rule of 5 violations (Lipinski): 2
  • SMILES: CCC[C@@H](C(=O)C(=O)N)NC(=O)C1N(C[C@H]2[C@@H]1C2(C)C)C(=O)C(C1CCCCC1)NC(=O)NC(C)(C)C
  • InChi: 1S/C27H45N5O5/c1-7-11-17(21(33)22(28)34)29-23(35)20-18-16(27(18,5)6)14-32(20)24(36)19(15-12-9-8-10-13-15)30-25(37)31-26(2,3)4/h15-20H,7-14H2,1-6H3,(H2,28,34)(H,29,35)(H2,30,31,37)/t16-,17-,18-,19?,20?/m0/s1
  • InChiKey: JCPXKWWNPBKSOC-YUUDKIHESA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Hepatitis C virus Hepatitis C virus serine protease, NS3/NS4A Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Echinococcus granulosus 60S ribosomal protein L8 Hepatitis C virus serine protease, NS3/NS4A   54 aa 48 aa 33.3 %
Trypanosoma congolense WD40 repeats, putative Hepatitis C virus serine protease, NS3/NS4A   54 aa 46 aa 28.3 %
Entamoeba histolytica hypothetical protein Hepatitis C virus serine protease, NS3/NS4A   54 aa 52 aa 23.1 %
Mycobacterium ulcerans Maf-like protein Hepatitis C virus serine protease, NS3/NS4A   54 aa 44 aa 38.6 %
Trypanosoma brucei gambiense expression site-associated gene 3 (ESAG3)-like protein, putative Hepatitis C virus serine protease, NS3/NS4A   54 aa 49 aa 28.6 %
Leishmania braziliensis hypothetical protein, conserved Hepatitis C virus serine protease, NS3/NS4A   54 aa 46 aa 26.1 %
Schistosoma mansoni hypothetical protein Hepatitis C virus serine protease, NS3/NS4A   54 aa 44 aa 29.5 %
Mycobacterium tuberculosis Membrane-associated phospholipase C 2 PlcB Hepatitis C virus serine protease, NS3/NS4A   54 aa 49 aa 32.7 %
Toxoplasma gondii hypothetical protein Hepatitis C virus serine protease, NS3/NS4A   54 aa 50 aa 28.0 %
Trypanosoma brucei hypothetical protein, conserved Hepatitis C virus serine protease, NS3/NS4A   54 aa 55 aa 30.9 %
Trypanosoma brucei expression site-associated gene 3 (ESAG3)-like protein Hepatitis C virus serine protease, NS3/NS4A   54 aa 49 aa 28.6 %
Schistosoma japonicum expressed protein Hepatitis C virus serine protease, NS3/NS4A   54 aa 44 aa 29.5 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0406 0.0739 1
Brugia malayi VAB-10A protein 0.0036 0.0016 0.0036
Leishmania major heat shock protein 83-1 0.0051 0.0046 0.0304
Loa Loa (eye worm) heat shock protein 75 0.0034 0.0013 0.0029
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0056 0.0055 0.0362
Trichomonas vaginalis inositol monophosphatase, putative 0.011 0.0161 0.0574
Trichomonas vaginalis CMGC family protein kinase 0.0054 0.0051 0.0176
Schistosoma mansoni terminal deoxycytidyl transferase 0.0039 0.0023 0.0019
Trypanosoma cruzi hexokinase, putative 0.0089 0.012 0.082
Loa Loa (eye worm) hypothetical protein 0.0034 0.0012 0.0027
Mycobacterium ulcerans glutaminase 0.1445 0.2765 1
Trypanosoma cruzi hypothetical protein, conserved 0.0207 0.0351 0.2433
Trypanosoma brucei unspecified product 0.0039 0.0023 0.0138
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.011 0.0161 1
Trichomonas vaginalis alpha-glucosidase, putative 0.0078 0.0098 0.0345
Echinococcus granulosus neutral alpha glucosidase AB 0.0078 0.0098 0.0094
Loa Loa (eye worm) hypothetical protein 0.0098 0.0138 0.0314
Echinococcus granulosus acetylcholinesterase 0.0287 0.0507 0.0503
Mycobacterium tuberculosis Methoxy mycolic acid synthase 4 MmaA4 (methyl mycolic acid synthase 4) (MMA4) (hydroxy mycolic acid synthase) 0.0037 0.0019 0.0202
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0186 0.0309 0.0704
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0186 0.0309 0.0704
Brugia malayi tailless protein 0.0088 0.0117 0.0267
Trichomonas vaginalis heat shock protein, putative 0.0044 0.0032 0.0105
Brugia malayi eukaryotic initiation factor 4A 0.003 0.0004 0.0009
Echinococcus multilocularis lysine specific demethylase 6a 0.0061 0.0066 0.0062
Leishmania major C-8 sterol isomerase-like protein 0.0731 0.1371 0.9563
Echinococcus granulosus inositol monophosphatase 1 0.011 0.0161 0.0157
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0039 0.0023 0.0019
Loa Loa (eye worm) hypothetical protein 0.0028 0.0001 0.0003
Trichomonas vaginalis maltase-glucoamylase, putative 0.0078 0.0098 0.0345
Plasmodium falciparum thioredoxin reductase 0.0056 0.0055 0.1578
Schistosoma mansoni BC026374 protein (S09 family) 0.0049 0.0041 0.0037
Schistosoma mansoni smad1 5 8 and 0.0034 0.0012 0.0008
Mycobacterium ulcerans heat shock protein 90 0.0048 0.004 0.009
Echinococcus granulosus JmjC domain containing protein 4 0.0061 0.0066 0.0062
Brugia malayi Hint module family protein 0.005 0.0043 0.0098
Trypanosoma cruzi PAB1-binding protein , putative 0.008 0.0102 0.0692
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0186 0.0309 0.0306
Loa Loa (eye worm) hypothetical protein 0.0062 0.0066 0.0151
Brugia malayi heat shock protein 90 0.0051 0.0046 0.0105
Brugia malayi Carboxylesterase family protein 0.0049 0.0041 0.0093
Echinococcus granulosus muscleblind protein 0.0164 0.0265 0.0262
Trichomonas vaginalis CAMK family protein kinase 0.0096 0.0134 0.0475
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0056 0.0055 0.0362
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0056 0.0055 0.0143
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0048 0.004 0.0036
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0023 0.0138
Trypanosoma brucei hexokinase, putative 0.0089 0.012 0.082
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0186 0.0309 0.0704
Trichomonas vaginalis glutathione reductase, putative 0.0056 0.0055 0.0187
Brugia malayi Pre-SET motif family protein 0.0092 0.0126 0.0286
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0049 0.0041 0.0138
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0039 0.0023 0.0072
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0035 0.0015 0.0157
Echinococcus multilocularis L aminoadipate semialdehyde 0.0084 0.0111 0.0107
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.004 0.0134
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0056 0.0055 0.0362
Brugia malayi Nuclear hormone receptor E75 0.0088 0.0117 0.0267
Loa Loa (eye worm) hypothetical protein 0.0287 0.0507 0.1154
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0078 0.0098 0.0223
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0186 0.0309 0.0704
Loa Loa (eye worm) jmjC domain-containing protein 0.0061 0.0066 0.0149
Schistosoma mansoni phd/f-box containing protein 0.0061 0.0066 0.0062
Trypanosoma brucei heat shock protein 90, putative 0.0051 0.0046 0.0304
Trypanosoma brucei trypanothione reductase 0.016 0.0259 0.179
Brugia malayi nuclear receptor NHR-88 0.0186 0.0309 0.0704
Echinococcus multilocularis mothers against decapentaplegic 5 0.0034 0.0012 0.0008
Plasmodium falciparum thioredoxin reductase 0.016 0.0259 0.7931
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0366 0.0659 0.8917
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0049 0.0041 0.0037
Leishmania major hexokinase, putative 0.0089 0.012 0.082
Brugia malayi jmjC domain containing protein 0.0061 0.0066 0.0149
Brugia malayi nuclear receptor RXR 0.0098 0.0138 0.0314
Brugia malayi MH2 domain containing protein 0.0034 0.0012 0.0027
Plasmodium vivax ataxin-2 like protein, putative 0.008 0.0102 0.3045
Schistosoma mansoni heat shock protein 0.0051 0.0046 0.0042
Loa Loa (eye worm) hypothetical protein 0.0049 0.0041 0.0093
Onchocerca volvulus 0.0049 0.0041 0.0087
Echinococcus multilocularis indoleamine 2,3 dioxygenase 2 0.0571 0.1061 0.1057
Onchocerca volvulus Protein ultraspiracle homolog 0.0186 0.0309 0.0698
Echinococcus multilocularis heat shock protein 90 0.0044 0.0032 0.0028
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0054 0.0051 0.034
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0139 0.0218 0.0215
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0054 0.0051 0.034
Brugia malayi beta-lactamase 0.0035 0.0015 0.0035
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0056 0.0055 0.1578
Echinococcus multilocularis jumonji domain containing protein 0.0129 0.0198 0.0195
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0139 0.0218 0.0215
Echinococcus granulosus indoleamine 23 dioxygenase 2 0.0571 0.1061 0.1057
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0139 0.0218 0.0215
Trichomonas vaginalis heat shock protein, putative 0.0037 0.0019 0.0058
Brugia malayi latrophilin 2 splice variant baaae 0.0069 0.0081 0.0184
Brugia malayi beta-lactamase family protein 0.0035 0.0015 0.0035
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0061 0.0066 0.0062
Plasmodium falciparum glutathione reductase 0.016 0.0259 0.7931
Leishmania major heat shock protein 83-1 0.0051 0.0046 0.0304
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0119 0.0177 0.059
Echinococcus granulosus heat shock protein 90 0.0051 0.0046 0.0042
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0056 0.0055 0.0362
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0186 0.0309 0.0704
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0054 0.0051 0.034
Echinococcus granulosus Polycystic kidney disease protein 0.0062 0.0066 0.0062
Loa Loa (eye worm) hypothetical protein 0.0062 0.0066 0.0151
Trypanosoma cruzi kinetoplast DNA-associated protein, putative 0.0036 0.0016 0.0092
Loa Loa (eye worm) helix-loop-helix DNA-binding domain-containing protein 0.012 0.0181 0.0411
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0227 0.0388 0.5226
Plasmodium vivax importin-beta 2, putative 0.0032 0.0009 0.0166
Trypanosoma cruzi sterol 24-c-methyltransferase, putative 0.0763 0.1434 1
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0514 0.0949 0.2159
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0036 0.0016 0.0012
Echinococcus granulosus neuroligin 0.0049 0.0041 0.0037
Onchocerca volvulus 0.0186 0.0309 0.0698
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0084 0.0111 0.0107
Echinococcus multilocularis dnaJ subfamily B 0.0814 0.1534 0.1531
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0119 0.0177 0.2362
Loa Loa (eye worm) jmjC domain-containing protein 0.0061 0.0066 0.0149
Plasmodium falciparum LCCL domain-containing protein 0.0062 0.0066 0.1939
Brugia malayi Helix-loop-helix DNA-binding domain containing protein 0.0121 0.0182 0.0414
Brugia malayi ImpB/MucB/SamB family protein 0.0039 0.0023 0.0051
Plasmodium vivax SET domain protein, putative 0.0092 0.0126 0.3793
Mycobacterium ulcerans DNA polymerase IV 0.0039 0.0023 0.0026
Loa Loa (eye worm) hypothetical protein 0.0088 0.0117 0.0267
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0351 0.0631 0.1435
Brugia malayi Thioredoxin reductase 0.016 0.0259 0.0589
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0044 0.0032 0.0028
Trichomonas vaginalis CAMK family protein kinase 0.0096 0.0134 0.0475
Brugia malayi Pre-SET motif family protein 0.0634 0.1184 0.2694
Schistosoma mansoni hypothetical protein 0.0062 0.0066 0.0062
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.011 0.0161 0.1107
Trichomonas vaginalis glucosylceramidase, putative 0.0337 0.0604 0.2176
Brugia malayi F/Y-rich N-terminus family protein 0.0051 0.0046 0.0105
Schistosoma mansoni nuclear receptor 0.0088 0.0117 0.0114
Loa Loa (eye worm) vesicular acetylcholine transporter unc-17 0.228 0.4394 1
Echinococcus granulosus phd:f box containing protein 0.0061 0.0066 0.0062
Echinococcus multilocularis transcription factor eb 0.0121 0.0182 0.0178
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0582 0.1081 0.3902
Echinococcus multilocularis RUN 0.0062 0.0066 0.0062
Loa Loa (eye worm) hypothetical protein 0.0088 0.0117 0.0267
Loa Loa (eye worm) hypothetical protein 0.0101 0.0143 0.0327
Loa Loa (eye worm) hypothetical protein 0.0035 0.0015 0.0035
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0039 0.0023 0.0138
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0056 0.0055 0.1193
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0092 0.0126 0.0122
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0186 0.0309 0.0306
Leishmania major heat shock protein 83-1 0.0051 0.0046 0.0304
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0582 0.1081 0.3902
Echinococcus multilocularis hexokinase 0.0089 0.012 0.0116
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0056 0.0055 0.0051
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0139 0.0218 0.0215
Plasmodium vivax glutathione reductase, putative 0.016 0.0259 0.7931
Brugia malayi nuclear receptor NHR-88 0.0088 0.0117 0.0267
Leishmania major heat shock protein 83-1 0.0051 0.0046 0.0304
Mycobacterium tuberculosis Carboxylesterase LipT 0.0049 0.0041 0.0505
Trypanosoma cruzi sterol 24-c-methyltransferase, putative 0.0037 0.0019 0.0111
Trypanosoma brucei PAB1-binding protein , putative 0.008 0.0102 0.0692
Giardia lamblia Fructose-bisphosphate aldolase 0.0582 0.1081 1
Plasmodium falciparum ataxin-2 like protein, putative 0.008 0.0102 0.3045
Echinococcus multilocularis carboxylesterase 5A 0.0287 0.0507 0.0503
Schistosoma mansoni rab6-interacting 0.0062 0.0066 0.0062
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0148 0.0236 0.0232
Echinococcus multilocularis lipoxygenase domain containing protein 0.0062 0.0066 0.0062
Toxoplasma gondii heat shock protein HSP90 0.0051 0.0046 0.132
Leishmania major heat shock protein 83-1 0.0051 0.0046 0.0304
Schistosoma mansoni cpg binding protein 0.006 0.0064 0.006
Echinococcus granulosus heat shock protein 90 0.0044 0.0032 0.0028
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0186 0.0309 0.0704
Schistosoma mansoni hypothetical protein 0.0036 0.0016 0.0012
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0366 0.0659 0.8917
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0119 0.0177 0.0174
Plasmodium falciparum heat shock protein 90 0.0051 0.0046 0.132
Echinococcus multilocularis microtubule associated protein 2 0.5154 1 1
Echinococcus granulosus para nitrobenzyl esterase 0.0049 0.0041 0.0037
Echinococcus granulosus hexokinase 0.0089 0.012 0.0116
Loa Loa (eye worm) hypothetical protein 0.0028 0.0001 0.0003
Trypanosoma brucei heat shock protein, putative 0.0051 0.0046 0.0304
Onchocerca volvulus 0.0056 0.0055 0.012
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0041 0.0026 0.0059
Mycobacterium tuberculosis Probable esterase LipL 0.0035 0.0015 0.0157
Loa Loa (eye worm) glutaminase 0.1445 0.2765 0.6293
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0186 0.0309 0.0306
Toxoplasma gondii NADPH-glutathione reductase 0.0056 0.0055 0.1578
Echinococcus granulosus importin subunit beta 1 0.0032 0.0009 0.0005
Echinococcus multilocularis snurportin 1 0.0345 0.0618 0.0615
Schistosoma mansoni steroid hormone receptor ad4bp 0.0186 0.0309 0.0306
Trichomonas vaginalis glucosylceramidase, putative 0.0514 0.0949 0.3424
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0023 0.0138
Loa Loa (eye worm) hypothetical protein 0.0088 0.0117 0.0267
Brugia malayi RNA recognition motif domain containing protein 0.0196 0.0328 0.0746
Schistosoma mansoni rab6-interacting 0.0062 0.0066 0.0062
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.003 0.0005 0.0019
Onchocerca volvulus 0.0203 0.0342 0.0773
Echinococcus granulosus BC026374 protein S09 family 0.0049 0.0041 0.0037
Loa Loa (eye worm) hypothetical protein 0.0088 0.0117 0.0267
Mycobacterium ulcerans glucose-6-phosphate 1-dehydrogenase 0.0062 0.0067 0.0187
Toxoplasma gondii heat shock protein 90, putative 0.0051 0.0046 0.132
Schistosoma mansoni nuclear hormone receptor 0.0088 0.0117 0.0114
Schistosoma mansoni hypothetical protein 0.0814 0.1534 0.1531
Entamoeba histolytica 90 kDa heat shock protein, putative 0.0034 0.0013 0.0092
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0049 0.0041 0.0037
Echinococcus multilocularis lysosomal alpha glucosidase 0.0351 0.0631 0.0627
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0078 0.0098 0.2931
Trypanosoma brucei sterol 24-c-methyltransferase, putative 0.0398 0.0722 0.5026
Loa Loa (eye worm) cytochrome P450 family protein 0.0048 0.004 0.0092
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0196 0.0328 0.0746
Brugia malayi beta-lactamase family protein 0.0035 0.0015 0.0035
Trichomonas vaginalis glucosylceramidase, putative 0.0337 0.0604 0.2176
Trichomonas vaginalis myo inositol monophosphatase, putative 0.011 0.0161 0.0574
Loa Loa (eye worm) heat shock protein 90 0.0051 0.0046 0.0105
Loa Loa (eye worm) acetylcholinesterase 1 0.0287 0.0507 0.1154
Echinococcus multilocularis cpg binding protein 0.006 0.0064 0.006
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0096 0.0134 0.013
Schistosoma mansoni serine/threonine protein kinase 0.0096 0.0134 0.013
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0088 0.0117 0.0114
Schistosoma mansoni hypothetical protein 0.0069 0.0081 0.0077
Plasmodium vivax hypothetical protein, conserved 0.0093 0.0127 0.3843
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0186 0.0309 0.0704
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0015 0.0088
Mycobacterium ulcerans aldehyde dehydrogenase 0.0185 0.0307 0.1059
Brugia malayi jmjC domain containing protein 0.0421 0.0768 0.1748
Echinococcus granulosus GPCR family 2 0.0032 0.0009 0.0005
Brugia malayi ecdysone receptor 0.0088 0.0117 0.0267
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0185 0.0307 0.0303
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0092 0.0126 0.0122
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0092 0.0126 0.0122
Trypanosoma cruzi hypothetical protein, conserved 0.0078 0.0098 0.0666
Onchocerca volvulus 0.0111 0.0162 0.0363
Loa Loa (eye worm) hypothetical protein 0.0088 0.0117 0.0267
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0054 0.0051 0.034
Brugia malayi RNA binding protein 0.0196 0.0328 0.0746
Brugia malayi Bromodomain containing protein 0.0093 0.0127 0.029
Loa Loa (eye worm) carboxylesterase 0.0049 0.0041 0.0093
Mycobacterium tuberculosis Conserved protein 0.0035 0.0015 0.0157
Brugia malayi Latrophilin receptor protein 2 0.0032 0.0009 0.002
Loa Loa (eye worm) hypothetical protein 0.0098 0.0138 0.0314
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0023 0.0138
Loa Loa (eye worm) hypothetical protein 0.0037 0.0019 0.0042
Trichomonas vaginalis CAMK family protein kinase 0.0096 0.0134 0.0475
Trichomonas vaginalis CMGC family protein kinase 0.0054 0.0051 0.0176
Entamoeba histolytica heat shock protein 90, putative 0.0051 0.0046 0.0403
Entamoeba histolytica hypothetical protein 0.0148 0.0236 0.216
Echinococcus multilocularis lipoxygenase domain containing protein 0.0062 0.0066 0.0062
Trypanosoma cruzi DNA polymerase kappa, putative 0.0039 0.0023 0.0138
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0582 0.1081 0.3902
Plasmodium vivax endoplasmin, putative 0.0051 0.0046 0.132
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0035 0.0015 0.0157
Brugia malayi hypothetical protein 0.0049 0.0041 0.0093
Brugia malayi TAR-binding protein 0.0196 0.0328 0.0746
Loa Loa (eye worm) MH1 domain-containing protein 0.0034 0.0012 0.0027
Echinococcus multilocularis muscleblind protein 0.0164 0.0265 0.0262
Trypanosoma cruzi polo-like protein kinase, putative 0.0096 0.0134 0.0917
Trichomonas vaginalis 6-phosphogluconolactonase, putative 0.0103 0.0147 0.0523
Schistosoma mansoni inositol monophosphatase 0.011 0.0161 0.0157
Schistosoma mansoni coup transcription factor 0.0186 0.0309 0.0306
Brugia malayi jmjC domain containing protein 0.0061 0.0066 0.0149
Brugia malayi ImpB/MucB/SamB family protein 0.0039 0.0023 0.0051
Brugia malayi glucose-6-phosphate dehydrogenase 0.0095 0.0131 0.0297
Schistosoma mansoni lipoxygenase 0.0128 0.0195 0.0191
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0039 0.0023 0.0019
Echinococcus granulosus carboxylesterase 5A 0.0287 0.0507 0.0503
Loa Loa (eye worm) hypothetical protein 0.0049 0.0041 0.0093
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0186 0.0309 0.0306
Schistosoma mansoni alpha-glucosidase 0.0302 0.0535 0.0532
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0186 0.0309 0.0704
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0056 0.0055 0.0051
Echinococcus granulosus Nuclear hormone receptor HR96 0.0088 0.0117 0.0114
Brugia malayi Glycosyl hydrolases family 31 protein 0.0078 0.0098 0.0223
Loa Loa (eye worm) hypothetical protein 0.0049 0.0041 0.0093
Plasmodium vivax heat shock protein 90, putative 0.0034 0.0013 0.0276
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0015 0.0046
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.011 0.0161 0.1107
Echinococcus multilocularis importin subunit beta 1 0.0032 0.0009 0.0005
Trypanosoma cruzi hypothetical protein, conserved 0.0078 0.0098 0.0666
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0015 0.0046
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0088 0.0117 0.0114
Trypanosoma brucei hexokinase 0.0089 0.012 0.082
Echinococcus granulosus peregrin 0.0093 0.0127 0.0124
Trypanosoma brucei DNA polymerase eta, putative 0.0039 0.0023 0.0138
Onchocerca volvulus 0.0062 0.0066 0.0144
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0093 0.0127 0.0124
Echinococcus granulosus acetylcholinesterase 0.0287 0.0507 0.0503
Schistosoma mansoni aldehyde dehydrogenase 0.0185 0.0307 0.0303
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0088 0.0117 0.0267
Plasmodium falciparum endoplasmin, putative 0.0037 0.0019 0.0467
Mycobacterium ulcerans methoxy mycolic acid synthase 4, MmaA4 0.0037 0.0019 0.0012
Echinococcus multilocularis muscleblind protein 1 0.0164 0.0265 0.0262
Onchocerca volvulus 0.0088 0.0117 0.0261
Schistosoma mansoni jumonji/arid domain-containing protein 0.0233 0.04 0.0396
Toxoplasma gondii LsmAD domain-containing protein 0.008 0.0102 0.3045
Trichomonas vaginalis heat shock protein, putative 0.0048 0.004 0.0135
Plasmodium vivax JmjC domain containing protein 0.0061 0.0066 0.192
Plasmodium falciparum heat shock protein 90, putative 0.0194 0.0325 1
Trichomonas vaginalis CMGC family protein kinase 0.0054 0.0051 0.0176
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0186 0.0309 0.0306
Trypanosoma brucei DNA polymerase IV, putative 0.0039 0.0023 0.0138
Leishmania major heat shock protein 83-1 0.0051 0.0046 0.0304
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0056 0.0055 0.0362
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0049 0.0041 0.0505
Trichomonas vaginalis glucosamine-6-phosphate isomerase, putative 0.0103 0.0147 0.0523
Loa Loa (eye worm) hypothetical protein 0.0543 0.1005 0.2287
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0345 0.0618 0.1407
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0023 0.0138
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.011 0.0161 0.1107
Leishmania major sterol 24-c-methyltransferase, putative 0.0763 0.1434 1
Echinococcus granulosus FTZ F1 alpha 0.0186 0.0309 0.0306
Echinococcus granulosus glucose 6 phosphate 1 dehydrogenase 0.0095 0.0131 0.0127
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0186 0.0309 0.0306
Schistosoma mansoni lipoxygenase 0.0238 0.0411 0.0407
Schistosoma mansoni hypothetical protein 0.0869 0.1641 0.1638
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0186 0.0309 0.0704
Onchocerca volvulus 0.0088 0.0117 0.0261
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0186 0.0309 0.0306
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.004 0.0134
Echinococcus granulosus heat shock protein 75 kDa mitochondrial 0.0034 0.0013 0.0009
Loa Loa (eye worm) MH2 domain-containing protein 0.0034 0.0012 0.0027
Trichomonas vaginalis heat shock protein, putative 0.0048 0.004 0.0135
Onchocerca volvulus Eukaryotic initiation factor 4A homolog 0.003 0.0004 0.0002
Schistosoma mansoni serine/threonine protein kinase 0.0054 0.0051 0.0048
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0056 0.0055 0.0124
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0036 0.0016 0.0012
Schistosoma mansoni hypothetical protein 0.0036 0.0016 0.0012
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0015 0.0046
Entamoeba histolytica myo-inositol monophosphatase, putative 0.011 0.0161 0.147
Leishmania major heat shock protein, putative 0.0034 0.0013 0.0069
Giardia lamblia PHD finger protein 15 0.0093 0.0127 0.1148
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0366 0.0659 0.89
Giardia lamblia Glucose-6-phosphate 1-dehydrogenase 0.0103 0.0147 0.1331
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0092 0.0126 0.0122
Trichomonas vaginalis CMGC family protein kinase 0.0054 0.0051 0.0176
Loa Loa (eye worm) hypothetical protein 0.0061 0.0065 0.0148
Plasmodium falciparum importin beta, putative 0.0032 0.0009 0.0166
Echinococcus multilocularis ecdysone induced protein 78C 0.0186 0.0309 0.0306
Loa Loa (eye worm) hexokinase 0.0056 0.0055 0.0126
Trypanosoma brucei heat shock protein, putative 0.0051 0.0046 0.0304
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0088 0.0117 0.0261
Loa Loa (eye worm) hypothetical protein 0.0032 0.0009 0.0021
Brugia malayi hypothetical protein 0.0062 0.0066 0.0151
Echinococcus granulosus mothers against decapentaplegic 5 0.0034 0.0012 0.0008
Plasmodium falciparum glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase 0.0103 0.0147 0.4457
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.011 0.0161 0.1107
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0287 0.0507 0.0503
Giardia lamblia Kinase, PLK 0.0096 0.0134 0.121
Onchocerca volvulus Alhambra homolog 0.0093 0.0127 0.0284
Trichomonas vaginalis glucosylceramidase, putative 0.0514 0.0949 0.3424
Onchocerca volvulus 0.0722 0.1354 0.3078
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0088 0.0117 0.0267
Plasmodium vivax heat shock protein, putative 0.0194 0.0325 1
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0101 0.0143 0.0327
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0056 0.0055 0.0362
Schistosoma mansoni vesicular acetylcholine transporter 0.228 0.4394 0.4391
Trypanosoma cruzi polo-like protein kinase, putative 0.0096 0.0134 0.0917
Leishmania major hypothetical protein, conserved 0.0035 0.0015 0.0088
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0056 0.0055 0.0362
Loa Loa (eye worm) hypothetical protein 0.0039 0.0023 0.0051
Trypanosoma cruzi heat shock protein 85, putative 0.0044 0.0032 0.0203
Onchocerca volvulus 0.0089 0.012 0.0267
Echinococcus multilocularis nuclear receptor nhr 48 0.0088 0.0117 0.0114
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.003 0.0004 0.0004
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0186 0.0309 0.0306
Echinococcus multilocularis Spectrin alpha actinin 0.0036 0.0016 0.0012
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0056 0.0055 0.0362
Loa Loa (eye worm) hypothetical protein 0.0035 0.0015 0.0035
Echinococcus multilocularis acetylcholinesterase 0.0287 0.0507 0.0503
Schistosoma mansoni hypothetical protein 0.0571 0.1061 0.1057
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0186 0.0309 0.0306
Mycobacterium leprae MYCOLIC ACID SYNTHASE PCAA (CYCLOPROPANE SYNTHASE) 0.0037 0.0019 0.0046
Loa Loa (eye worm) hypothetical protein 0.0069 0.0081 0.0184
Brugia malayi Growth-Arrest-Specific Protein 2 Domain containing protein 0.0036 0.0016 0.0036
Brugia malayi hexokinase type II 0.0028 0.0001 0.0003
Brugia malayi hypothetical protein 0.025 0.0433 0.0986
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0088 0.0117 0.0114
Echinococcus granulosus lipoxygenase domain containing protein 0.0062 0.0066 0.0062
Onchocerca volvulus Huntingtin homolog 0.025 0.0433 0.098
Brugia malayi RNA, U transporter 1 0.0092 0.0125 0.0285
Mycobacterium leprae POSSIBLE FATTY ACID SYNTHASE 0.0037 0.0019 0.0046
Loa Loa (eye worm) TAR-binding protein 0.0196 0.0328 0.0746
Plasmodium falciparum hexokinase 0.0089 0.012 0.3617
Plasmodium vivax glucose-6-phosphate 1-dehydrogenase, putative 0.0103 0.0147 0.4457
Schistosoma mansoni tar DNA-binding protein 0.0196 0.0328 0.0324
Trichomonas vaginalis spcc417.12 protein, putative 0.0049 0.0041 0.0138
Schistosoma mansoni retinoic acid receptor RXR 0.0186 0.0309 0.0306
Entamoeba histolytica heat shock protein 90, putative 0.0051 0.0046 0.0403
Brugia malayi Nuclear hormone receptor E75 0.0088 0.0117 0.0267
Brugia malayi Inositol-1 0.011 0.0161 0.0367
Mycobacterium tuberculosis Probable lipase LipD 0.0035 0.0015 0.0157
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0139 0.0218 0.0215
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0406 0.0739 1
Trypanosoma brucei heat shock protein, putative 0.0051 0.0046 0.0304
Brugia malayi Doublecortin family protein 0.0062 0.0066 0.0151
Brugia malayi hypothetical protein 0.0062 0.0066 0.0151
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.0005 0.005
Echinococcus granulosus tar DNA binding protein 0.0196 0.0328 0.0324
Echinococcus multilocularis inositol monophosphatase 1 0.011 0.0161 0.0157
Loa Loa (eye worm) hypothetical protein 0.005 0.0043 0.0098
Mycobacterium leprae METHOXY MYCOLIC ACID SYNTHASE 1 MMAA1 (METHYL MYCOLIC ACID SYNTHASE 1) (MMA1) (HYDROXY MYCOLIC ACID SYNTHASE) 0.0037 0.0019 0.0046
Toxoplasma gondii heat shock protein 75, putative 0.0034 0.0013 0.0276
Loa Loa (eye worm) hypothetical protein 0.0088 0.0117 0.0267
Onchocerca volvulus 0.0089 0.012 0.0267
Mycobacterium tuberculosis Conserved protein 0.0035 0.0015 0.0157
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0186 0.0309 0.0704
Brugia malayi PHD-finger family protein 0.0034 0.0012 0.0027
Echinococcus granulosus transcription factor eb 0.0121 0.0182 0.0178
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0186 0.0309 0.0704
Trypanosoma cruzi glucose-6-phosphate 1-dehydrogenase, putative 0.0095 0.0131 0.0894
Mycobacterium tuberculosis Cyclopropane-fatty-acyl-phospholipid synthase 1 CmaA1 (cyclopropane fatty acid synthase) (CFA synthase) (cyclopropane mycolic ac 0.0037 0.0019 0.0202
Trypanosoma cruzi DNA polymerase eta, putative 0.0039 0.0023 0.0138
Onchocerca volvulus 0.0092 0.0126 0.028
Toxoplasma gondii PHD-finger domain-containing protein 0.0093 0.0127 0.3843
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0049 0.0041 0.0505
Chlamydia trachomatis glucose-6-phosphate 1-dehydrogenase 0.0095 0.0131 1
Trypanosoma brucei heat shock protein, putative 0.0051 0.0046 0.0304
Echinococcus granulosus dna polymerase kappa 0.0039 0.0023 0.0019
Loa Loa (eye worm) jmjC domain-containing protein 0.0233 0.04 0.0911
Treponema pallidum fructose-bisphosphate aldolase 0.0582 0.1081 1
Loa Loa (eye worm) hypothetical protein 0.0032 0.0009 0.002
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0078 0.0098 0.0345
Trichomonas vaginalis heat shock protein, putative 0.003 0.0004 0.0006
Echinococcus granulosus hexokinase 0.0089 0.012 0.0116
Leishmania major DNA polymerase kappa, putative 0.0039 0.0023 0.0138
Schistosoma mansoni DNA polymerase eta 0.0039 0.0023 0.0019
Schistosoma mansoni smad1 5 8 and 0.0034 0.0012 0.0008
Brugia malayi CXXC zinc finger family protein 0.0057 0.0058 0.0131
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0582 0.1081 1
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0056 0.0055 0.1578
Onchocerca volvulus 0.0049 0.0041 0.0087
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0056 0.0055 0.0362
Giardia lamblia Heat shock protein HSP 90-alpha 0.0044 0.0032 0.026
Loa Loa (eye worm) hypothetical protein 0.003 0.0004 0.0009
Leishmania major sterol 24-c-methyltransferase, putative 0.0763 0.1434 1
Treponema pallidum hexokinase (hxk) 0.0089 0.012 0.108
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0186 0.0309 0.0704
Schistosoma mansoni protein phosphatase 2C 0.0061 0.0066 0.0062
Schistosoma mansoni acetylcholinesterase 0.0049 0.0041 0.0037
Brugia malayi MH1 domain containing protein 0.0034 0.0012 0.0027
Brugia malayi Calcitonin receptor-like protein seb-1 0.0101 0.0143 0.0327
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0582 0.1081 1
Trypanosoma brucei Sterol methyltransferase, putative 0.0763 0.1434 1
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0186 0.0309 0.0306
Onchocerca volvulus 0.0049 0.0041 0.0087
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0582 0.1081 0.3902
Mycobacterium tuberculosis Methoxy mycolic acid synthase 3 MmaA3 (methyl mycolic acid synthase 3) (MMA3) (hydroxy mycolic acid synthase) 0.0037 0.0019 0.0202
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0049 0.0041 0.0037
Schistosoma mansoni hypothetical protein 0.0111 0.0162 0.0158
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0035 0.0015 0.0157
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0054 0.0051 0.034
Leishmania major DNA polymerase eta, putative 0.0039 0.0023 0.0138
Loa Loa (eye worm) hypothetical protein 0.0186 0.0309 0.0704
Trichomonas vaginalis glucosylceramidase, putative 0.0514 0.0949 0.3424
Trypanosoma brucei hexokinase 0.0089 0.012 0.082
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.3494 0.6762 0.676
Loa Loa (eye worm) thioredoxin reductase 0.016 0.0259 0.0589
Echinococcus multilocularis endoplasmin 0.0048 0.004 0.0036
Loa Loa (eye worm) hypothetical protein 0.0164 0.0265 0.0604
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0119 0.0177 0.0404
Onchocerca volvulus Bile acid receptor homolog 0.0186 0.0309 0.0698
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0119 0.0177 0.059
Loa Loa (eye worm) hypothetical protein 0.0372 0.0671 0.1527
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0064 0.0072 0.0068
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0092 0.0126 0.0122
Echinococcus granulosus thyroid hormone receptor alpha 0.0088 0.0117 0.0114
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0185 0.0307 0.2123
Trichomonas vaginalis CAMK family protein kinase 0.0096 0.0134 0.0475
Trypanosoma cruzi DNA polymerase kappa, putative 0.0039 0.0023 0.0138
Mycobacterium ulcerans carboxylesterase, LipT 0.0049 0.0041 0.0093
Trypanosoma cruzi heat shock protein 85, putative 0.0051 0.0046 0.0304
Trichomonas vaginalis myo inositol monophosphatase, putative 0.011 0.0161 0.0574
Mycobacterium tuberculosis Possible mycolic acid synthase UmaA 0.0037 0.0019 0.0202
Onchocerca volvulus Hexokinase homolog 0.0056 0.0055 0.012
Plasmodium falciparum ataxin-2 like protein, putative 0.008 0.0102 0.3045
Loa Loa (eye worm) hypothetical protein 0.0373 0.0675 0.1535
Trichomonas vaginalis endoplasmin, putative 0.0037 0.0019 0.0058
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0015 0.0088
Brugia malayi Hexokinase family protein 0.0056 0.0055 0.0126
Loa Loa (eye worm) hypothetical protein 0.0098 0.0138 0.0314
Brugia malayi hypothetical protein 0.0098 0.0138 0.0314
Schistosoma mansoni tar DNA-binding protein 0.0196 0.0328 0.0324
Onchocerca volvulus 0.0037 0.0019 0.0036
Entamoeba histolytica hypothetical protein 0.0148 0.0236 0.216
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0139 0.0218 0.0497
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0186 0.0309 0.0306
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0119 0.0177 0.1221
Schistosoma mansoni smad1 5 8 and 0.0034 0.0012 0.0008
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0186 0.0309 0.0704
Onchocerca volvulus Glucosylceramidase homolog 0.0337 0.0604 0.1369
Echinococcus multilocularis phd:f box containing protein 0.0061 0.0066 0.0062
Loa Loa (eye worm) hypothetical protein 0.012 0.0181 0.0411
Trypanosoma cruzi hypothetical protein, conserved 0.0207 0.0351 0.2433
Mycobacterium ulcerans cyclopropane-fatty-acyl-phospholipid synthase 2 CmaA2 0.0037 0.0019 0.0012
Trichomonas vaginalis glucosylceramidase, putative 0.0514 0.0949 0.3424
Loa Loa (eye worm) hexokinase 0.0089 0.012 0.0273
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0032 0.0009 0.0005
Brugia malayi nuclear hormone receptor family member odr-7 0.0088 0.0117 0.0267
Echinococcus granulosus lysosomal alpha glucosidase 0.0351 0.0631 0.0627
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0039 0.0023 0.0255
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0023 0.0138
Echinococcus granulosus heat shock protein 0.0051 0.0046 0.0042
Onchocerca volvulus 0.0049 0.0041 0.0087
Echinococcus multilocularis tar DNA binding protein 0.0196 0.0328 0.0324
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0061 0.0066 0.0439
Loa Loa (eye worm) hypothetical protein 0.0035 0.0015 0.0035
Schistosoma mansoni glucose-6-phosphate 1-dehydrogenase 0.0095 0.0131 0.0127
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0061 0.0066 0.0439
Brugia malayi jmjC domain containing protein 0.0061 0.0066 0.0149
Brugia malayi Smad1 0.0034 0.0012 0.0027
Brugia malayi hypothetical protein 0.008 0.0102 0.0232
Trichomonas vaginalis DNA polymerase eta, putative 0.0039 0.0023 0.0072
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0078 0.0098 0.0884
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0582 0.1081 0.3902
Mycobacterium tuberculosis Cyclopropane-fatty-acyl-phospholipid synthase 2 CmaA2 (cyclopropane fatty acid synthase) (CFA synthase) (cyclopropane mycolic ac 0.0037 0.0019 0.0202
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0056 0.0055 0.1193
Brugia malayi hypothetical protein 0.0148 0.0236 0.0536
Loa Loa (eye worm) hypothetical protein 0.0037 0.0019 0.0042
Trypanosoma brucei heat shock protein 90, putative 0.0051 0.0046 0.0304
Echinococcus multilocularis jumonji domain containing 1A 0.0061 0.0066 0.0062
Brugia malayi Hint module family protein 0.005 0.0043 0.0098
Treponema pallidum heat shock protein 90 0.0048 0.004 0.0337
Echinococcus multilocularis geminin 0.0869 0.1641 0.1638
Schistosoma mansoni thyroid hormone receptor 0.0186 0.0309 0.0306
Brugia malayi Carboxylesterase family protein 0.0049 0.0041 0.0093
Echinococcus multilocularis dna polymerase kappa 0.0039 0.0023 0.0019
Mycobacterium ulcerans mycolic acid synthase PcaA 0.0037 0.0019 0.0012
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0034 0.0012 0.0008
Loa Loa (eye worm) jmjC domain-containing protein 0.0192 0.032 0.0729
Mycobacterium tuberculosis Probable oxidoreductase 0.0406 0.0739 1
Echinococcus multilocularis hexokinase 0.0089 0.012 0.0116
Schistosoma mansoni survival motor neuron protein 0.0111 0.0162 0.0158
Echinococcus multilocularis FTZ F1 alpha 0.0186 0.0309 0.0306
Loa Loa (eye worm) hypothetical protein 0.025 0.0433 0.0986
Entamoeba histolytica DEAD/DEAH box helicase, putative 0.003 0.0004 0.001
Loa Loa (eye worm) hypothetical protein 0.0088 0.0117 0.0267
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0023 0.0138
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0421 0.0768 0.0764
Trypanosoma cruzi DNA polymerase kappa, putative 0.0039 0.0023 0.0138
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0064 0.0072 0.0068
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0186 0.0309 0.0306
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0186 0.0309 0.0704
Leishmania major trypanothione reductase 0.016 0.0259 0.179
Schistosoma mansoni polycystin 1-related 0.0062 0.0066 0.0062
Schistosoma mansoni importin beta-1 0.0032 0.0009 0.0005
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0186 0.0309 0.0306
Mycobacterium tuberculosis Probable lipase LipE 0.0035 0.0015 0.0157
Schistosoma mansoni jumonji/arid domain-containing protein 0.0233 0.04 0.0396
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0186 0.0309 0.0704
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0139 0.0218 0.0215
Echinococcus multilocularis mitogen activated protein kinase 0.0054 0.0051 0.0048
Echinococcus multilocularis BC026374 protein (S09 family) 0.0049 0.0041 0.0037
Echinococcus granulosus hexokinase type 2 0.0089 0.012 0.0116
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0186 0.0309 0.0306
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0049 0.0041 0.0037
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0061 0.0066 0.192
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0032 0.0009 0.0005
Mycobacterium ulcerans aldehyde dehydrogenase 0.0185 0.0307 0.1059
Echinococcus multilocularis heat shock protein 90 0.0051 0.0046 0.0042
Mycobacterium leprae METHOXY MYCOLIC ACID SYNTHASE 4 MMAA4 (METHYL MYCOLIC ACID SYNTHASE 4) (MMA4) (HYDROXY MYCOLIC ACID SYNTHASE) 0.0037 0.0019 0.0046
Mycobacterium ulcerans methoxy mycolic acid synthase 2, MmaA2 0.0037 0.0019 0.0012
Mycobacterium tuberculosis Methoxy mycolic acid synthase 2 MmaA2 (methyl mycolic acid synthase 2) (MMA2) (hydroxy mycolic acid synthase) 0.0037 0.0019 0.0202
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0056 0.0055 0.069
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0098 0.0138 0.0134
Leishmania major hypothetical protein, conserved 0.0061 0.0066 0.0439
Brugia malayi serine/threonine-protein kinase plk-2 0.0096 0.0134 0.0305
Trichomonas vaginalis CAMK family protein kinase 0.0096 0.0134 0.0475
Echinococcus granulosus Spectrin alpha actinin 0.0036 0.0016 0.0012
Mycobacterium leprae CYCLOPROPANE-FATTY-ACYL-PHOSPHOLIPID SYNTHASE 2 CMAA2 (CYCLOPROPANE FATTY ACID SYNTHASE) (CFA SYNTHASE) (CYCLOPROPANE MYCOLIC AC 0.0037 0.0019 0.0046
Loa Loa (eye worm) hypothetical protein 0.0186 0.0309 0.0704
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0284 0.05 0.1764
Giardia lamblia Kinase, CMGC MAPK 0.0054 0.0051 0.0442
Brugia malayi MH2 domain containing protein 0.0034 0.0012 0.0027
Brugia malayi nuclear hormone receptor 0.0186 0.0309 0.0704
Schistosoma mansoni cpg binding protein 0.0057 0.0058 0.0054
Schistosoma mansoni smad 0.0034 0.0012 0.0008
Schistosoma mansoni kinase 0.0049 0.0042 0.0038
Loa Loa (eye worm) hypothetical protein 0.0186 0.0309 0.0704
Schistosoma mansoni hypothetical protein 0.0036 0.0016 0.0012
Brugia malayi glutathione reductase 0.016 0.0259 0.0589
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0096 0.0134 0.013
Trichomonas vaginalis alpha-glucosidase, putative 0.0078 0.0098 0.0345
Entamoeba histolytica hypothetical protein 0.0148 0.0236 0.216
Schistosoma mansoni heat shock protein 0.0034 0.0013 0.0009
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0054 0.0051 0.034
Schistosoma mansoni microtubule-associated protein tau 0.5154 1 1
Loa Loa (eye worm) hypothetical protein 0.005 0.0043 0.0098
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0406 0.0739 1
Leishmania major alpha glucosidase II subunit, putative 0.0078 0.0098 0.0666
Entamoeba histolytica hexokinase 2 0.0089 0.012 0.1089
Trypanosoma cruzi trypanothione reductase, putative 0.016 0.0259 0.179
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0186 0.0309 0.0698
Mycobacterium ulcerans methoxy mycolic acid synthase 3, MmaA3 0.0037 0.0019 0.0012
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0078 0.0098 0.0884
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.003 0.0005 0.0019
Plasmodium falciparum glutathione reductase 0.0056 0.0055 0.1578
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0056 0.0055 0.0362
Leishmania major heat shock protein 83-1 0.0051 0.0046 0.0304
Brugia malayi nuclear receptor NHR-67 0.0088 0.0117 0.0267
Brugia malayi Glycosyl hydrolases family 31 protein 0.0029 0.0003 0.0006
Echinococcus granulosus cpg binding protein 0.006 0.0064 0.006
Toxoplasma gondii glucose-6-phosphate 1-dehydrogenase 0.0103 0.0147 0.4457
Toxoplasma gondii histone lysine methyltransferase SET1 0.0112 0.0164 0.4978
Echinococcus multilocularis PHD finger protein rhinoceros 0.0093 0.0127 0.0124
Echinococcus multilocularis mitogen activated protein kinase 3 0.0054 0.0051 0.0048
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0098 0.0138 0.0134
Schistosoma mansoni glutaminase 0.1445 0.2765 0.2762
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0088 0.0117 0.0114
Toxoplasma gondii glucose-6-phosphate 1-dehydrogenase 0.0062 0.0067 0.1956
Trichomonas vaginalis set domain proteins, putative 0.0722 0.1354 0.4893
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0099 0.0139 0.1704
Plasmodium vivax hypothetical protein, conserved 0.0035 0.0015 0.0359
Brugia malayi indoleamine 2,3-dioxygenase 0.0571 0.1061 0.2414
Trypanosoma cruzi Heat shock protein 83, putative 0.0051 0.0046 0.0304
Loa Loa (eye worm) PHD-finger family protein 0.0093 0.0127 0.029
Loa Loa (eye worm) hypothetical protein 0.0093 0.0127 0.029
Leishmania major eukaryotic initiation factor 4a, putative 0.003 0.0004 0.0007
Loa Loa (eye worm) RNA binding protein 0.0196 0.0328 0.0746
Onchocerca volvulus 0.0084 0.0111 0.0246
Schistosoma mansoni hypothetical protein 0.0148 0.0236 0.0232
Onchocerca volvulus Vesicular acetylcholine transporter homolog 0.228 0.4394 1
Echinococcus multilocularis peregrin 0.0093 0.0127 0.0124
Echinococcus granulosus ecdysone induced protein 78C 0.0186 0.0309 0.0306
Brugia malayi hypothetical protein 0.0088 0.0117 0.0267
Trypanosoma brucei sterol 24-c-methyltransferase, putative 0.0763 0.1434 1
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0101 0.0143 0.0327
Echinococcus multilocularis dna polymerase eta 0.0039 0.0023 0.0019
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.016 0.0259 0.3469
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0098 0.0138 0.0314
Toxoplasma gondii ABC1 family protein 0.0035 0.0015 0.0359
Trichomonas vaginalis alpha-glucosidase, putative 0.0078 0.0098 0.0345
Schistosoma mansoni transcription factor LCR-F1 0.0148 0.0236 0.0232
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.003 0.0004 0.0004
Loa Loa (eye worm) DR-78 0.0088 0.0117 0.0267
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0186 0.0309 0.0306
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0098 0.0138 0.0134
Echinococcus granulosus vesicular acetylcholine transporter 0.228 0.4394 0.4391
Leishmania major hypothetical protein, conserved 0.008 0.0102 0.0692
Trypanosoma cruzi heat shock protein 85, putative 0.0051 0.0046 0.0304
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0015 0.0046
Echinococcus multilocularis para nitrobenzyl esterase 0.0049 0.0041 0.0037
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0023 0.0138
Loa Loa (eye worm) beta-lactamase 0.0035 0.0015 0.0035
Brugia malayi AF-10 protein 0.003 0.0005 0.0012
Loa Loa (eye worm) hexokinase 0.0089 0.012 0.0273
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0185 0.0307 0.4117
Echinococcus granulosus dnaJ subfamily B 0.0814 0.1534 0.1531
Echinococcus granulosus endoplasmin 0.0048 0.004 0.0036
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0056 0.0055 0.0362
Loa Loa (eye worm) hypothetical protein 0.0088 0.0117 0.0267
Trichomonas vaginalis CAMK family protein kinase 0.0096 0.0134 0.0475
Echinococcus granulosus snurportin 1 0.0345 0.0618 0.0615
Brugia malayi nuclear receptor RXR 0.0088 0.0117 0.0267
Leishmania major heat shock protein 83-1 0.0051 0.0046 0.0304
Schistosoma mansoni jumonji domain containing protein 0.0061 0.0066 0.0062
Trichomonas vaginalis glucosylceramidase, putative 0.0514 0.0949 0.3424
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0092 0.0126 0.3793
Loa Loa (eye worm) CXXC zinc finger family protein 0.0057 0.0058 0.0131
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0056 0.0055 0.0362
Plasmodium falciparum JmjC domain-containing protein, putative 0.0061 0.0066 0.192
Brugia malayi ecdysteroid receptor 0.0186 0.0309 0.0704
Schistosoma mansoni Smad4 0.0034 0.0012 0.0008
Trypanosoma brucei importin beta-1 subunit, putative 0.0032 0.0009 0.0045
Echinococcus multilocularis smad 0.0034 0.0012 0.0008
Leishmania major heat shock protein 83-1 0.0051 0.0046 0.0304
Echinococcus granulosus mitogen activated protein kinase 0.0054 0.0051 0.0048
Schistosoma mansoni hypothetical protein 0.0032 0.0009 0.0005
Echinococcus granulosus jumonji domain containing 1A 0.0061 0.0066 0.0062
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0238 0.0411 0.0407
Echinococcus granulosus smad 0.0034 0.0012 0.0008
Toxoplasma gondii Hsp90 domain-containing protein 0.0194 0.0325 1
Loa Loa (eye worm) indoleamine 2,3-dioxygenase 0.0571 0.1061 0.2414
Loa Loa (eye worm) glucose-6-phosphate dehydrogenase 0.0095 0.0131 0.0297
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0731 0.1371 0.3121
Loa Loa (eye worm) hypothetical protein 0.0037 0.0019 0.0042
Trichomonas vaginalis glutaminase, putative 0.1445 0.2765 1
Loa Loa (eye worm) hypothetical protein 0.0186 0.0309 0.0704
Loa Loa (eye worm) hypothetical protein 0.0088 0.0117 0.0267
Trichomonas vaginalis glucosylceramidase, putative 0.0337 0.0604 0.2176
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0056 0.0055 0.0143
Onchocerca volvulus 0.0035 0.0015 0.0029
Trypanosoma cruzi trypanothione reductase, putative 0.0056 0.0055 0.0362
Schistosoma mansoni alpha glucosidase 0.0078 0.0098 0.0094
Onchocerca volvulus 0.0035 0.0015 0.0029
Loa Loa (eye worm) hypothetical protein 0.0035 0.0015 0.0035
Brugia malayi orphan nuclear receptor NR2E1 0.0088 0.0117 0.0267
Mycobacterium ulcerans DNA polymerase IV 0.0039 0.0023 0.0026
Echinococcus multilocularis heat shock protein 75 kDa, mitochondrial 0.0034 0.0013 0.0009
Trypanosoma brucei heat shock protein, putative 0.0051 0.0046 0.0304
Echinococcus granulosus hexokinase 0.0089 0.012 0.0116
Brugia malayi MAP kinase sur-1 0.0054 0.0051 0.0117
Giardia lamblia NADH oxidase lateral transfer candidate 0.0056 0.0055 0.0471
Trypanosoma brucei DNA polymerase IV, putative 0.0039 0.0023 0.0138
Echinococcus granulosus lysine specific demethylase 5A 0.0233 0.04 0.0396
Echinococcus multilocularis vesicular acetylcholine transporter 0.228 0.4394 0.4391
Leishmania major heat shock protein 83-1 0.0051 0.0046 0.0304
Onchocerca volvulus 0.0057 0.0058 0.0125
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0186 0.0309 0.0306
Trypanosoma cruzi Eukaryotic initiation factor 4A-1 0.003 0.0004 0.0007
Loa Loa (eye worm) MH2 domain-containing protein 0.0493 0.0908 0.2067
Plasmodium vivax thioredoxin reductase, putative 0.016 0.0259 0.7931
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0186 0.0309 0.0306
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.003 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0036 0.0016 0.0036
Echinococcus granulosus mitogen activated protein kinase 3 0.0054 0.0051 0.0048
Schistosoma mansoni cpg binding protein 0.006 0.0064 0.006
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0035 0.0015 0.0035
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0084 0.0111 0.0252
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0056 0.0055 0.1578
Trypanosoma brucei hypothetical protein, conserved 0.0207 0.0351 0.2433
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0731 0.1371 0.9563
Loa Loa (eye worm) hypothetical protein 0.0186 0.0309 0.0704
Trypanosoma cruzi heat shock protein 85, putative 0.0051 0.0046 0.0304
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0185 0.0307 0.0303
Echinococcus granulosus thioredoxin glutathione reductase 0.0162 0.0262 0.0258
Leishmania major hexokinase, putative 0.0089 0.012 0.082
Echinococcus multilocularis heat shock protein 0.0051 0.0046 0.0042
Schistosoma mansoni hypothetical protein 0.003 0.0005 0.0002
Mycobacterium tuberculosis Mycolic acid synthase PcaA (cyclopropane synthase) 0.0037 0.0019 0.0202
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0039 0.0023 0.0051
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0366 0.0659 0.8917
Echinococcus granulosus RUN 0.0062 0.0066 0.0062
Loa Loa (eye worm) hypothetical protein 0.0092 0.0126 0.0286
Entamoeba histolytica deoxycytidyl transferase, putative 0.0039 0.0023 0.0184
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0048 0.004 0.0261
Echinococcus granulosus dna polymerase eta 0.0039 0.0023 0.0019
Onchocerca volvulus 0.0089 0.012 0.0267
Brugia malayi Carboxylesterase family protein 0.0049 0.0041 0.0093
Loa Loa (eye worm) nuclear hormone receptor 0.0088 0.0117 0.0267
Loa Loa (eye worm) Smad1 0.0034 0.0012 0.0027
Loa Loa (eye worm) hypothetical protein 0.0035 0.0015 0.0035
Loa Loa (eye worm) hypothetical protein 0.0731 0.1371 0.3121
Brugia malayi hypothetical protein 0.0098 0.0138 0.0314
Loa Loa (eye worm) hypothetical protein 0.0287 0.0507 0.1154
Loa Loa (eye worm) hypothetical protein 0.0084 0.0111 0.0252
Loa Loa (eye worm) hypothetical protein 0.0088 0.0117 0.0267
Loa Loa (eye worm) hypothetical protein 0.0186 0.0309 0.0704
Leishmania major heat shock protein 83-1 0.0051 0.0046 0.0304
Schistosoma mansoni tar DNA-binding protein 0.0196 0.0328 0.0324
Trichomonas vaginalis CAMK family protein kinase 0.0096 0.0134 0.0475
Schistosoma mansoni loxhd1 0.0062 0.0066 0.0062
Brugia malayi glutaminase DH11.1 0.1445 0.2765 0.6293
Trypanosoma cruzi heat shock protein, putative 0.0034 0.0013 0.0069
Schistosoma mansoni hexokinase 0.0089 0.012 0.0116
Loa Loa (eye worm) hypothetical protein 0.0186 0.0309 0.0704
Mycobacterium tuberculosis Possible fatty acid synthase 0.0037 0.0019 0.0202
Onchocerca volvulus 0.0062 0.0066 0.0144
Trypanosoma cruzi sterol 24-c-methyltransferase, putative 0.0763 0.1434 1
Schistosoma mansoni hypothetical protein 0.0571 0.1061 0.1057
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0088 0.0117 0.0261
Schistosoma mansoni nuclear receptor 0.0088 0.0117 0.0114
Leishmania major heat shock protein 83-1 0.0051 0.0046 0.0304
Echinococcus multilocularis Smad4 0.0034 0.0012 0.0008
Entamoeba histolytica hexokinase 1 0.0089 0.012 0.1089
Echinococcus multilocularis lysosomal alpha glucosidase 0.0351 0.0631 0.0627
Trypanosoma brucei glucose-6-phosphate 1-dehydrogenase 0.0095 0.0131 0.0894
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0048 0.004 0.0342
Echinococcus multilocularis beta LACTamase domain containing family member 0.0035 0.0015 0.0012
Mycobacterium ulcerans cyclopropane-fatty-acyl-phospholipid synthase 0.0037 0.0019 0.0012
Trypanosoma brucei importin beta-1 subunit, putative 0.0032 0.0009 0.0045
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0092 0.0126 0.0122
Onchocerca volvulus 0.0035 0.0015 0.0029
Mycobacterium ulcerans mycolic acid synthase UmaA 0.0037 0.0019 0.0012
Brugia malayi steroid hormone receptor 0.0186 0.0309 0.0704
Echinococcus multilocularis lysine specific demethylase 5A 0.0229 0.0394 0.039
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0039 0.0023 0.0019
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0119 0.0177 0.0174
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0284 0.05 0.6701
Plasmodium vivax hexokinase, putative 0.0089 0.012 0.3617
Brugia malayi Carboxylesterase family protein 0.0049 0.0041 0.0093
Schistosoma mansoni jumonji domain containing protein 0.0359 0.0646 0.0642
Echinococcus granulosus Nuclear hormone receptor HR96 0.0088 0.0117 0.0114
Leishmania major eukaryotic initiation factor 4a, putative 0.003 0.0004 0.0007
Plasmodium falciparum phd finger protein, putative 0.0093 0.0127 0.3843
Loa Loa (eye worm) glutathione reductase 0.016 0.0259 0.0589
Leishmania major heat shock protein 83-1 0.0051 0.0046 0.0304
Trichomonas vaginalis alpha-glucosidase, putative 0.0078 0.0098 0.0345
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0023 0.0138
Schistosoma mansoni heat shock protein 0.0051 0.0046 0.0042
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0056 0.0055 0.1578
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0111 0.0162 0.0368
Trypanosoma brucei Heat shock protein 83, putative 0.0051 0.0046 0.0304
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0139 0.0218 0.0497
Trichomonas vaginalis glucosylceramidase, putative 0.0337 0.0604 0.2176
Trichomonas vaginalis heat shock protein, putative 0.0051 0.0046 0.0157
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0056 0.0055 0.1578
Mycobacterium tuberculosis Probable reductase 0.0366 0.0659 0.8917
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0015 0.0046
Loa Loa (eye worm) hypothetical protein 0.0088 0.0117 0.0267
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0088 0.0117 0.0114
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0048 0.004 0.0494
Loa Loa (eye worm) hypothetical protein 0.019 0.0318 0.0723
Loa Loa (eye worm) hypothetical protein 0.0088 0.0117 0.0267
Toxoplasma gondii PHD-finger domain-containing protein 0.0093 0.0127 0.3843
Trypanosoma brucei heat shock protein, putative 0.0051 0.0046 0.0304
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0634 0.1184 0.2694
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0061 0.0066 0.0439
Loa Loa (eye worm) glutaminase 2 0.1445 0.2765 0.6293
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0284 0.05 0.6753
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0186 0.0309 0.0306
Brugia malayi nuclear hormone receptor 0.0088 0.0117 0.0267
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0034 0.0012 0.0008
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0096 0.0134 0.0305
Schistosoma mansoni zinc finger protein 0.0088 0.0117 0.0114
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0421 0.0768 0.0764
Brugia malayi photoreceptor-specific nuclear receptor 0.0186 0.0309 0.0704
Trichomonas vaginalis sucrase-isomaltase, putative 0.0078 0.0098 0.0345
Brugia malayi PHD-finger family protein 0.0093 0.0127 0.029
Loa Loa (eye worm) hypothetical protein 0.0049 0.0041 0.0093
Schistosoma mansoni thyroid hormone receptor 0.0186 0.0309 0.0306
Schistosoma mansoni gliotactin 0.0049 0.0041 0.0037
Trypanosoma brucei C-8 sterol isomerase, putative 0.0731 0.1371 0.9563
Schistosoma mansoni neuroligin 3 (S09 family) 0.0049 0.0041 0.0037
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0582 0.1081 0.3902
Loa Loa (eye worm) hypothetical protein 0.025 0.0433 0.0986
Trypanosoma cruzi glucose-6-phosphate 1-dehydrogenase, putative 0.0031 0.0007 0.0032
Loa Loa (eye worm) inositol-1 0.011 0.0161 0.0367
Schistosoma mansoni hypothetical protein 0.0133 0.0206 0.0202
Schistosoma mansoni tar DNA-binding protein 0.0196 0.0328 0.0324
Schistosoma mansoni hypothetical protein 0.0093 0.0127 0.0124
Echinococcus granulosus TGF beta signal transducer SmadC 0.0034 0.0012 0.0008
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0023 0.0138
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0088 0.0117 0.0114
Loa Loa (eye worm) hypothetical protein 0.0049 0.0041 0.0093
Plasmodium vivax heat shock protein 86, putative 0.0051 0.0046 0.132
Brugia malayi hypothetical protein 0.0051 0.0047 0.0106
Trypanosoma brucei protein kinase, putative 0.0054 0.0051 0.034
Brugia malayi Muscleblind-like protein 0.0164 0.0265 0.0604
Loa Loa (eye worm) hypothetical protein 0.0049 0.0041 0.0093
Trypanosoma cruzi sterol 24-c-methyltransferase, putative 0.0763 0.1434 1
Trypanosoma brucei glucosidase, putative 0.0078 0.0098 0.0666
Plasmodium vivax hypothetical protein, conserved 0.0034 0.0012 0.0261
Leishmania major heat shock protein 83-1 0.0051 0.0046 0.0304
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0034 0.0012 0.0261
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0015 0.0012
Toxoplasma gondii HEAT repeat-containing protein 0.0032 0.0009 0.0166
Loa Loa (eye worm) carboxylesterase 0.0049 0.0041 0.0093
Brugia malayi hypothetical protein 0.0088 0.0117 0.0267
Trypanosoma cruzi Glucose-6-phosphate dehydrogenase, putative 0.003 0.0006 0.002
Trypanosoma brucei Eukaryotic initiation factor 4A-1 0.003 0.0004 0.0007
Trypanosoma brucei heat shock protein, putative 0.0051 0.0046 0.0304
Echinococcus granulosus lipoxygenase domain containing protein 0.0062 0.0066 0.0062
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0366 0.0659 0.8917
Mycobacterium tuberculosis Probable cyclopropane-fatty-acyl-phospholipid synthase UfaA1 (cyclopropane fatty acid synthase) (CFA synthase) 0.0037 0.0019 0.0202
Echinococcus granulosus lysine specific demethylase 6a 0.0061 0.0066 0.0062
Schistosoma mansoni nuclear hormone receptor 0.0088 0.0117 0.0114
Leishmania major heat shock protein 83-1 0.0051 0.0046 0.0304
Plasmodium falciparum heat shock protein 90, putative 0.003 0.0004 0.0017
Echinococcus multilocularis hexokinase 0.0089 0.012 0.0116
Echinococcus granulosus survival motor neuron protein 1 0.0543 0.1005 0.1001
Schistosoma mansoni nuclear hormone receptor 0.0186 0.0309 0.0306
Loa Loa (eye worm) hypothetical protein 0.0035 0.0015 0.0035
Mycobacterium ulcerans glucose-6-phosphate 1-dehydrogenase 0.0095 0.0131 0.042
Echinococcus granulosus jumonji domain containing protein 0.0129 0.0198 0.0195
Schistosoma mansoni hypothetical protein 0.0032 0.0009 0.0005
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0078 0.0098 0.0345
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0148 0.0236 0.0232
Schistosoma mansoni inositol monophosphatase 0.011 0.0161 0.0157
Trichomonas vaginalis esterase, putative 0.0035 0.0015 0.0046
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.011 0.0161 0.053
Toxoplasma gondii thioredoxin reductase 0.016 0.0259 0.7931
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0582 0.1081 0.3902
Schistosoma mansoni hypothetical protein 0.0345 0.0618 0.0615
Brugia malayi Endoplasmin precursor 0.0051 0.0046 0.0105
Trichomonas vaginalis glucosylceramidase, putative 0.0355 0.0639 0.2304
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0186 0.0309 0.0306
Schistosoma mansoni hypothetical protein 0.0869 0.1641 0.1638
Echinococcus granulosus geminin 0.0869 0.1641 0.1638
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0088 0.0117 0.0114
Brugia malayi jmjC domain containing protein 0.0233 0.04 0.0911
Trypanosoma cruzi DNA polymerase kappa, putative 0.0039 0.0023 0.0138
Loa Loa (eye worm) jmjC domain-containing protein 0.0061 0.0066 0.0149
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0054 0.0051 0.0117
Entamoeba histolytica serine/threonine protein kinase, putative 0.0096 0.0134 0.1218
Trypanosoma brucei polo-like protein kinase 0.0096 0.0134 0.0917
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0032 0.0009 0.0005
Schistosoma mansoni endoplasmin 0.0051 0.0046 0.0042
Trypanosoma brucei heat shock protein 84, putative 0.0034 0.0013 0.0069
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0186 0.0309 0.0704
Mycobacterium tuberculosis Conserved hypothetical protein 0.0039 0.0023 0.0255
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0054 0.0051 0.148
Brugia malayi hypothetical protein 0.0543 0.1005 0.2287
Entamoeba histolytica hypothetical protein 0.0148 0.0236 0.216
Echinococcus granulosus L aminoadipate semialdehyde 0.0084 0.0111 0.0107
Brugia malayi Nuclear hormone receptor-like 1 0.0098 0.0138 0.0314
Echinococcus granulosus nuclear receptor nhr 48 0.0088 0.0117 0.0114
Leishmania major hypothetical protein, conserved 0.0207 0.0351 0.2433
Loa Loa (eye worm) hypothetical protein 0.0098 0.0138 0.0314
Loa Loa (eye worm) hypothetical protein 0.0164 0.0265 0.0604
Brugia malayi Steroid receptor seven-up type 2 0.0186 0.0309 0.0704
Trypanosoma cruzi heat shock protein 90, putative 0.0044 0.0032 0.0203
Brugia malayi Importin beta-1 subunit 0.0032 0.0009 0.0021
Toxoplasma gondii hexokinase 0.0089 0.012 0.3617
Trichomonas vaginalis glucosylceramidase, putative 0.0337 0.0604 0.2176
Brugia malayi hexokinase 0.0089 0.012 0.0273
Plasmodium vivax multidomain scavenger receptor, putative 0.0062 0.0066 0.1939
Echinococcus granulosus PHD finger protein rhinoceros 0.0093 0.0127 0.0124
Loa Loa (eye worm) latrophilin receptor protein 2 0.0032 0.0009 0.002
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0186 0.0309 0.0704
Loa Loa (eye worm) spectraplakin 0.0036 0.0016 0.0036
Trichomonas vaginalis mercuric reductase, putative 0.0056 0.0055 0.0187
Schistosoma mansoni RAR-like nuclear receptor 0.0186 0.0309 0.0306
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0119 0.0177 0.0174
Onchocerca volvulus 0.0049 0.0041 0.0087
Mycobacterium ulcerans methoxy mycolic acid synthase 5 MmaA5 0.0037 0.0019 0.0012
Echinococcus multilocularis JmjC domain containing protein 4 0.0061 0.0066 0.0062
Treponema pallidum NADH oxidase 0.0056 0.0055 0.0471
Trypanosoma brucei DNA polymerase IV, putative 0.0039 0.0023 0.0138
Echinococcus multilocularis thyroid hormone receptor alpha 0.0186 0.0309 0.0306
Brugia malayi Nuclear hormone receptor-like 1 0.0186 0.0309 0.0704
Echinococcus granulosus histone lysine methyltransferase setb 0.0092 0.0126 0.0122
Loa Loa (eye worm) nuclear receptor NHR-67 0.0088 0.0117 0.0267
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0056 0.0055 0.0362
Leishmania major heat shock protein 83-1 0.0051 0.0046 0.0304
Onchocerca volvulus Huntingtin homolog 0.025 0.0433 0.098
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0032 0.0009 0.002
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0098 0.0138 0.0134
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0035 0.0015 0.0035
Loa Loa (eye worm) hypothetical protein 0.0088 0.0117 0.0267
Schistosoma mansoni nuclear receptor nhr-48 0.0088 0.0117 0.0114
Mycobacterium tuberculosis Methoxy mycolic acid synthase 1 MmaA1 (methyl mycolic acid synthase 1) (MMA1) (hydroxy mycolic acid synthase) 0.0037 0.0019 0.0202
Echinococcus multilocularis acetylcholinesterase 0.0287 0.0507 0.0503
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0099 0.0139 0.1834
Loa Loa (eye worm) hypothetical protein 0.0186 0.0309 0.0704
Mycobacterium tuberculosis Conserved protein 0.0035 0.0015 0.0157
Loa Loa (eye worm) hypothetical protein 0.0098 0.0138 0.0314
Onchocerca volvulus Serine\/threonine kinase homolog 0.0096 0.0134 0.0299
Trichomonas vaginalis alpha-glucosidase, putative 0.0078 0.0098 0.0345
Loa Loa (eye worm) endoplasmin 0.0051 0.0046 0.0105
Brugia malayi nuclear hormone receptor family member nhr-6 0.0088 0.0117 0.0267
Brugia malayi vesicular acetylcholine transporter unc-17 0.228 0.4394 1
Treponema pallidum glucose-6-phosphate 1-dehydrogenase 0.0095 0.0131 0.1179
Brugia malayi conserved hypotetical protein 0.0088 0.0117 0.0267
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0186 0.0309 0.0704
Toxoplasma gondii aldehyde dehydrogenase 0.0185 0.0307 0.9413
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0054 0.0051 0.034
Mycobacterium ulcerans aldehyde dehydrogenase 0.0185 0.0307 0.1059
Loa Loa (eye worm) hypothetical protein 0.0049 0.0041 0.0093
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0056 0.0055 0.0362
Schistosoma mansoni hypothetical protein 0.0032 0.0009 0.0005
Trypanosoma cruzi hexokinase, putative 0.0089 0.012 0.082
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0088 0.0117 0.0114
Echinococcus granulosus Smad4 0.0034 0.0012 0.0008
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.003 0.0005 0.005
Loa Loa (eye worm) transcription factor SMAD2 0.0493 0.0908 0.2067
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0087 0.0117 0.0113
Echinococcus granulosus Desert hedgehog protein 0.0183 0.0302 0.0299
Trichomonas vaginalis glucosylceramidase, putative 0.0355 0.0639 0.2304
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0125 0.0189 0.0185
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0023 0.0138
Echinococcus multilocularis Polycystic kidney disease protein 0.0062 0.0066 0.0062
Trypanosoma brucei heat shock protein, putative 0.0051 0.0046 0.0304
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0056 0.0055 0.0051
Giardia lamblia Heat shock protein HSP 90-alpha 0.0051 0.0046 0.0394
Brugia malayi S-adenosyl-methionine cycloartenol-C24-methyltransferase 0.0372 0.0671 0.1527
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0056 0.0055 0.0143
Giardia lamblia DINP protein human, muc B family 0.0039 0.0023 0.0174
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0096 0.0134 0.0917
Loa Loa (eye worm) hypothetical protein 0.0061 0.0066 0.0149
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0582 0.1081 0.3902
Brugia malayi Carboxylesterase family protein 0.0287 0.0507 0.1154
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0041 0.0026 0.0059
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0088 0.0117 0.0114
Echinococcus multilocularis hedgehog 0.0183 0.0302 0.0299
Brugia malayi jmjC domain containing protein 0.0061 0.0066 0.0149
Brugia malayi Cytochrome P450 family protein 0.0048 0.004 0.0092
Giardia lamblia Grp94/Hsp90 0.0048 0.004 0.0337
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0111 0.0162 0.0369
Trichomonas vaginalis glucosylceramidase, putative 0.0337 0.0604 0.2176
Echinococcus multilocularis GPCR, family 2 0.0032 0.0009 0.0005
Loa Loa (eye worm) hypothetical protein 0.0029 0.0003 0.0006
Trichomonas vaginalis glucosylceramidase, putative 0.0514 0.0949 0.3424
Echinococcus multilocularis hexokinase type 2 0.0089 0.012 0.0116
Trypanosoma cruzi heat shock protein 90, putative 0.0051 0.0046 0.0304
Trypanosoma brucei sterol 24-c-methyltransferase, putative 0.0763 0.1434 1
Brugia malayi Glycosyl hydrolases family 31 protein 0.0351 0.0631 0.1435
Echinococcus multilocularis glucose 6 phosphate 1 dehydrogenase 0.0095 0.0131 0.0127
Schistosoma mansoni tar DNA-binding protein 0.0196 0.0328 0.0324
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0049 0.0041 0.0037
Echinococcus multilocularis neuroligin 0.0049 0.0041 0.0037
Brugia malayi MH1 domain containing protein 0.0034 0.0012 0.0027
Trichomonas vaginalis glucosylceramidase, putative 0.0337 0.0604 0.2176
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0139 0.0218 0.0215
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0056 0.0055 0.0362
Mycobacterium tuberculosis Probable glucose-6-phosphate 1-dehydrogenase Zwf2 (G6PD) 0.0033 0.001 0.0087
Leishmania major heat shock protein 83-1 0.0051 0.0046 0.0304
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0061 0.0066 0.192
Echinococcus multilocularis survival motor neuron protein 1 0.0543 0.1005 0.1001
Onchocerca volvulus Heat shock protein 75 kDa, mitochondrial homolog 0.0034 0.0013 0.0023
Trichomonas vaginalis glucosamine-6-phosphate isomerase, putative 0.0103 0.0147 0.0523
Schistosoma mansoni aldehyde dehydrogenase 0.0185 0.0307 0.0303
Brugia malayi Carboxylesterase family protein 0.0287 0.0507 0.1154
Loa Loa (eye worm) hexokinase type II 0.0089 0.012 0.0273
Echinococcus multilocularis thioredoxin glutathione reductase 0.0162 0.0262 0.0258
Loa Loa (eye worm) carboxylesterase 0.0287 0.0507 0.1154
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0056 0.0055 0.0362
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0186 0.0309 0.0704
Brugia malayi Hsp90 protein 0.0034 0.0013 0.0029
Mycobacterium tuberculosis Probable dehydrogenase 0.0366 0.0659 0.8917
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0032 0.0009 0.0005
Schistosoma mansoni phosphatidylserine receptor 0.0061 0.0066 0.0062
Trypanosoma brucei hypothetical protein, conserved 0.0035 0.0015 0.0088
Echinococcus granulosus beta LACTamase domain containing family member 0.0035 0.0015 0.0012
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0514 0.0949 0.2159
Loa Loa (eye worm) hypothetical protein 0.0061 0.0066 0.0149
Mycobacterium tuberculosis Probable hydrolase 0.0035 0.0015 0.0157
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0186 0.0309 0.0704
Schistosoma mansoni alpha-glucosidase 0.0302 0.0535 0.0532
Loa Loa (eye worm) steroid hormone receptor 0.0186 0.0309 0.0704
Leishmania major glucose-6-phosphate 1-dehydrogenase, putative 0.0095 0.0131 0.0894
Brugia malayi Nuclear hormone receptor-like 1 0.0098 0.0138 0.0314
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0238 0.0411 0.0407
Trypanosoma cruzi PAB1-binding protein , putative 0.008 0.0102 0.0692
Brugia malayi Hexokinase family protein 0.0089 0.012 0.0273
Loa Loa (eye worm) doublecortin family protein 0.0062 0.0066 0.0151
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.011 0.0161 0.4894
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0015 0.0012
Trypanosoma cruzi Eukaryotic initiation factor 4A-1 0.003 0.0004 0.0007
Echinococcus multilocularis neutral alpha glucosidase AB 0.0078 0.0098 0.0094
Loa Loa (eye worm) hypothetical protein 0.008 0.0102 0.0232
Brugia malayi MH2 domain containing protein 0.0493 0.0908 0.2067
Schistosoma mansoni hypothetical protein 0.0032 0.0009 0.0005
Schistosoma mansoni endoplasmin 0.0051 0.0046 0.0042

Activities

Activity type Activity value Assay description Source Reference
Ki (binding) = 54 nM Inhibition of HCV genotype H 1a NS3/4A protease ChEMBL. 17444623
Ki (binding) = 54 nM Inhibition of HCV genotype H 1a NS3/4A protease ChEMBL. 17444623

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

No external resources registered for this compound

Bibliographic References

1 literature reference was collected for this gene.

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