Detailed information for compound 553894

Basic information

Technical information
  • TDR Targets ID: 553894
  • Name: N-[1-[(3S,5S,8R,9S,10S,13S,14S)-3-(dimethylam ino)-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14, 15,16,17-tetradecahydro-1H-cyclopenta[a]phena nthren-17-yl]ethyl]-N-methyl-acetamide
  • MW: 402.656 | Formula: C26H46N2O
  • H donors: 0 H acceptors: 1 LogP: 6.08 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: CN(C(C1CC[C@@H]2[C@]1(C)CC[C@H]1[C@H]2CC[C@@H]2[C@]1(C)CC[C@@H](C2)N(C)C)C)C(=O)C
  • InChi: 1S/C26H46N2O/c1-17(28(7)18(2)29)22-10-11-23-21-9-8-19-16-20(27(5)6)12-14-25(19,3)24(21)13-15-26(22,23)4/h17,19-24H,8-16H2,1-7H3/t17?,19-,20-,21-,22?,23-,24-,25-,26+/m0/s1
  • InChiKey: VPOYXIYUORUTSW-PXALIONTSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N-[1-[(3S,5S,8R,9S,10S,13S,14S)-3-(dimethylamino)-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]ethyl]-N-methylacetamide
  • N-[1-[(3S,5S,8R,9S,10S,13S,14S)-3-(dimethylamino)-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]ethyl]-N-methyl-ethanamide
  • epipachysamine A
  • N-[1-[(3S,5S,8R,9S,10S,13S,14S)-3-dimethylamino-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]ethyl]-N-methylacetamide
  • N-[1-[(3S,5S,8R,9S,10S,13S,14S)-3-dimethylamino-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]ethyl]-N-methyl-acetamide
  • N-[1-[(3S,5S,8R,9S,10S,13S,14S)-3-dimethylamino-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]ethyl]-N-methyl-ethanamide
  • 2309-42-4
  • Acetamide, N-(3-beta-(dimethylamino)-5-alpha-pregnan-20-alpha-yl)-N-methyl-

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Entamoeba histolytica hypothetical protein 0.0146 0.0147 0.1447
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0055 0.0038 0.0218
Wolbachia endosymbiont of Brugia malayi membrane associated signal transduction histidine kinase 0.0108 0.0102 0.0407
Giardia lamblia Histone acetyltransferase GCN5 0.0077 0.0065 0.0733
Echinococcus multilocularis neuroligin 0.0071 0.0058 0.0058
Mycobacterium leprae PUTATIVE TWO COMPONENT SENSOR HISTIDINE KINASE SENX3 0.0108 0.0102 0.0263
Loa Loa (eye worm) LGC-31 protein 0.005 0.0032 0.0226
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0191 0.0201 0.1612
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.005 0.0032 0.0032
Mycobacterium ulcerans acyl-CoA synthetase 0.0035 0.0015 0.0044
Plasmodium falciparum casein kinase 1 0.0039 0.0019 0.0099
Loa Loa (eye worm) hypothetical protein 0.0101 0.0093 0.065
Loa Loa (eye worm) hypothetical protein 0.0047 0.0028 0.0195
Brugia malayi Nuclear hormone receptor family member nhr-40 0.003 0.0008 0.0058
Brugia malayi Bromodomain containing protein 0.0044 0.0025 0.0175
Brugia malayi Nuclear hormone receptor family member nhr-14 0.003 0.0008 0.0058
Trypanosoma brucei heat shock protein, putative 0.0349 0.039 0.3131
Brugia malayi Nuclear hormone receptor family member nhr-25 0.003 0.0008 0.0058
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0035 0.0015 0.0044
Mycobacterium ulcerans hypothetical protein 0.0149 0.015 0.045
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.005 0.0032 0.0289
Schistosoma mansoni hypothetical protein 0.0082 0.0071 0.0071
Trypanosoma cruzi PAB1-binding protein , putative 0.0052 0.0034 0.0276
Brugia malayi Nuclear hormone receptor family member nhr-25 0.003 0.0008 0.0058
Schistosoma mansoni RAR-like nuclear receptor 0.003 0.0008 0.0008
Echinococcus multilocularis dna polymerase eta 0.0023 0.0000098932 0.0000098932
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0038 0.0017 0.0193
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.005 0.0032 0.0226
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0074 0.0061 0.049
Brugia malayi ImpB/MucB/SamB family protein 0.0023 0.0000098932 0.0001
Trichomonas vaginalis two component sensor and regulator histidine kinase bacteria, putative 0.0108 0.0102 0.0916
Trypanosoma cruzi heat shock protein 90, putative 0.0349 0.039 0.3131
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0272 0.0298 0.0298
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.1064 0.1245 1
Mycobacterium ulcerans acyl-CoA synthetase 0.0121 0.0117 0.035
Loa Loa (eye worm) heat shock protein 75 0.0124 0.0121 0.0841
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.009 0.008 0.024
Trichomonas vaginalis esterase, putative 0.0149 0.015 0.1351
Onchocerca volvulus 0.0038 0.0017 0.0156
Schistosoma mansoni cellular tumor antigen P53 0.03 0.0332 0.0332
Brugia malayi Carboxylesterase family protein 0.0071 0.0058 0.0401
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0074 0.0061 0.0602
Trypanosoma cruzi DNA topoisomerase III, putative 0.0089 0.0078 0.0629
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.009 0.0079 0.0079
Loa Loa (eye worm) hypothetical protein 0.005 0.0032 0.0226
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0071 0.0058 0.0172
Toxoplasma gondii ABC1 family protein 0.0149 0.015 0.0889
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.003 0.0008 0.0008
Brugia malayi beta-lactamase family protein 0.0149 0.015 0.1047
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.009 0.0079 0.0554
Loa Loa (eye worm) hypothetical protein 0.009 0.008 0.0559
Plasmodium vivax DNA topoisomerase 3, putative 0.0089 0.0078 0.047
Brugia malayi RNA recognition motif domain containing protein 0.0062 0.0046 0.0322
Brugia malayi PHD-finger family protein 0.0031 0.001 0.0067
Brugia malayi jmjC domain containing protein 0.0056 0.0039 0.0273
Plasmodium falciparum cysteine proteinase falcipain 2a 0.005 0.0032 0.0182
Mycobacterium ulcerans two component sensory transduction histidine kinase MtrB 0.0108 0.0102 0.0305
Brugia malayi Nuclear hormone receptor family member nhr-41 0.003 0.0008 0.0058
Echinococcus multilocularis lysine specific demethylase 5A 0.021 0.0223 0.0223
Loa Loa (eye worm) hypothetical protein 0.0121 0.0117 0.0813
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0284 0.0312 0.3074
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.003 0.0008 0.0008
Loa Loa (eye worm) bromodomain containing protein 0.0024 0.0001 0.0008
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0092 0.0082 0.0656
Mycobacterium ulcerans acetyl-CoA synthetase 0.0035 0.0015 0.0044
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0139 0.0138 0.0414
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0191 0.0201 0.1612
Loa Loa (eye worm) hypothetical protein 0.0077 0.0065 0.0451
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.005 0.0032 0.0032
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.005 0.0032 0.0226
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0026 0.0003 0.0024
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.003 0.0008 0.0008
Toxoplasma gondii exonuclease III APE 0.0055 0.0038 0.0186
Trypanosoma cruzi cytochrome P450, putative 0.0027 0.0005 0.004
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0046 0.0046
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0035 0.0015 0.0102
Mycobacterium leprae TWO COMPONENT SENSOR HISTIDINE KINASE PRRB 0.0108 0.0102 0.0263
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0161 0.0165 0.0567
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0038 0.0017 0.0017
Plasmodium vivax DNA gyrase subunit B, putative 0.0988 0.1155 0.7195
Loa Loa (eye worm) jmjC domain-containing protein 0.0056 0.0039 0.0273
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0055 0.0038 0.0428
Entamoeba histolytica acyl-CoA synthetase, putative 0.0121 0.0117 0.115
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0064 0.0048 0.0048
Loa Loa (eye worm) hypothetical protein 0.003 0.0008 0.0058
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0108 0.0102 0.0586
Loa Loa (eye worm) hypothetical protein 0.005 0.0032 0.0226
Plasmodium vivax endoplasmin, putative 0.0349 0.039 0.2416
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0161 0.0165 0.0982
Loa Loa (eye worm) hypothetical protein 0.0149 0.015 0.1047
Trichomonas vaginalis heat shock protein, putative 0.0241 0.026 0.2344
Brugia malayi AMP-binding enzyme family protein 0.0121 0.0117 0.0813
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0012 0.011
Echinococcus multilocularis transcription factor btf3 0.0034 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0037 0.0016 0.0111
Loa Loa (eye worm) hypothetical protein 0.0056 0.0039 0.0273
Schistosoma mansoni nAChR subunit 0.005 0.0032 0.0032
Trypanosoma brucei DNA topoisomerase ii 0.1064 0.1245 1
Loa Loa (eye worm) hypothetical protein 0.003 0.0008 0.0058
Brugia malayi Carboxylesterase family protein 0.0422 0.0477 0.3328
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.005 0.0032 0.0289
Plasmodium vivax heat shock protein, putative 0.0124 0.0121 0.0733
Brugia malayi Carboxylesterase family protein 0.0422 0.0477 0.3328
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0055 0.0038 0.0265
Plasmodium falciparum heat shock protein 90, putative 0.0124 0.0121 0.0733
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0149 0.015 0.045
Leishmania major heat shock protein 83-1 0.0349 0.039 0.3131
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0161 0.0165 0.0495
Echinococcus multilocularis inositol monophosphatase 1 0.0074 0.0061 0.0061
Onchocerca volvulus 0.0039 0.0019 0.0171
Echinococcus multilocularis Niemann Pick C1 protein 0.0284 0.0312 0.0312
Loa Loa (eye worm) carboxylesterase 0.0422 0.0477 0.3328
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0023 0.0000098932 0.0000098932
Leishmania major hypothetical protein, conserved 0.0056 0.0039 0.0314
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0038 0.0017 0.0017
Trypanosoma cruzi casein kinase, putative 0.0039 0.0019 0.0152
Brugia malayi TAR-binding protein 0.0062 0.0046 0.0322
Echinococcus granulosus thioredoxin glutathione reductase 0.0047 0.0029 0.0029
Trypanosoma brucei heat shock protein, putative 0.0349 0.039 0.3131
Mycobacterium tuberculosis Probable hydrolase 0.0149 0.015 0.045
Brugia malayi hypothetical protein 0.0071 0.0058 0.0401
Toxoplasma gondii DNA topoisomerase domain-containing protein 0.0089 0.0078 0.0439
Echinococcus granulosus casein kinase I delta 0.0039 0.0019 0.0019
Trypanosoma cruzi cysteine peptidase, putative 0.0191 0.0201 0.1612
Entamoeba histolytica cysteine proteinase, putative 0.0026 0.0003 0.003
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.003 0.0008 0.0008
Trypanosoma cruzi casein kinase, putative 0.0039 0.0019 0.0152
Trypanosoma cruzi heat shock protein 85, putative 0.0241 0.026 0.2091
Schistosoma mansoni jumonji domain containing protein 0.0056 0.0039 0.0039
Leishmania major casein kinase, putative 0.0039 0.0019 0.0152
Loa Loa (eye worm) endoplasmin 0.0349 0.039 0.272
Loa Loa (eye worm) hypothetical protein 0.009 0.008 0.0559
Brugia malayi jmjC domain containing protein 0.0056 0.0039 0.0273
Brugia malayi Papain family cysteine protease containing protein 0.0026 0.0003 0.0022
Loa Loa (eye worm) hypothetical protein 0.005 0.0032 0.0226
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0035 0.0015 0.0044
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0055 0.0038 0.0304
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0062 0.0047 0.0375
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.005 0.0032 0.0226
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.005 0.0032 0.0032
Leishmania major DNA topoisomerase 1A 0.0089 0.0078 0.0629
Mycobacterium tuberculosis Possible two component sensor kinase TcrY 0.0108 0.0102 0.0305
Plasmodium falciparum DNA topoisomerase 3, putative 0.0089 0.0078 0.047
Brugia malayi beta-NAC-like protein 0.0034 0.0013 0.0091
Mycobacterium ulcerans TetR family transcriptional regulator 0.2807 0.3332 1
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0161 0.0165 0.0811
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.005 0.0032 0.0289
Loa Loa (eye worm) hypothetical protein 0.0121 0.0117 0.0813
Treponema pallidum chemotaxis histidine kinase (cheA) 0.0108 0.0102 0.0407
Trypanosoma cruzi DNA topoisomerase III, putative 0.0089 0.0078 0.0629
Mycobacterium ulcerans fatty-acid-CoA ligase 0.009 0.008 0.024
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0284 0.0312 0.2806
Leishmania major 4-coumarate:coa ligase-like protein 0.0121 0.0117 0.0936
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0066 0.0052 0.0155
Loa Loa (eye worm) hypothetical protein 0.009 0.008 0.0559
Echinococcus granulosus GPCR family 2 0.0047 0.0028 0.0028
Echinococcus granulosus Niemann Pick C1 protein 0.0284 0.0312 0.0312
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0038 0.0017 0.0137
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0038 0.0017 0.0137
Echinococcus multilocularis casein kinase I alpha 0.0039 0.0019 0.0019
Trichomonas vaginalis sensory transduction histidine kinase, putative 0.0108 0.0102 0.0916
Echinococcus multilocularis sterol regulatory element binding protein 0.0085 0.0074 0.0074
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0121 0.0117 0.035
Trypanosoma cruzi casein kinase, putative 0.0039 0.0019 0.0152
Loa Loa (eye worm) hypothetical protein 0.0302 0.0334 0.2328
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0121 0.0117 0.035
Entamoeba histolytica cysteine protease, putative 0.0026 0.0003 0.003
Schistosoma mansoni protein phosphatase 2C 0.0056 0.0039 0.0039
Leishmania major cathepsin L-like protease 0.005 0.0032 0.0258
Brugia malayi beta-lactamase 0.0149 0.015 0.1047
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.005 0.0032 0.0289
Brugia malayi excitatory GABA receptor EXP-1A 0.005 0.0032 0.0226
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0012 0.011
Toxoplasma gondii thioredoxin reductase 0.0047 0.0029 0.013
Onchocerca volvulus Alhambra homolog 0.003 0.0008 0.0075
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0161 0.0165 0.0453
Leishmania major mitochondrial DNA topoisomerase II 0.1064 0.1245 1
Entamoeba histolytica DNA topoisomerase II, putative 0.087 0.1014 1
Loa Loa (eye worm) hypothetical protein 0.005 0.0032 0.0225
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.005 0.0032 0.0032
Echinococcus granulosus nAChR subunit 0.0027 0.0005 0.0005
Echinococcus multilocularis DNA topoisomerase 3 beta 1 0.0089 0.0078 0.0078
Brugia malayi cytoplasmic intermediate filament protein 0.0042 0.0023 0.0158
Brugia malayi CHE-14 protein 0.0085 0.0074 0.0519
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0422 0.0477 0.0477
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0027 0.0005 0.0033
Trypanosoma cruzi heat shock protein 90, putative 0.0241 0.026 0.2091
Echinococcus granulosus BC026374 protein S09 family 0.0071 0.0058 0.0058
Onchocerca volvulus 0.0149 0.015 0.1352
Echinococcus multilocularis nAChR subunit 0.0027 0.0005 0.0005
Mycobacterium tuberculosis Transcriptional regulatory repressor protein (TetR-family) EthR 0.2807 0.3332 1
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.005 0.0032 0.0226
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0191 0.0201 0.1612
Plasmodium vivax casein kinase 1, putative 0.0039 0.0019 0.0099
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0058 0.0041 0.0041
Onchocerca volvulus 0.003 0.0008 0.0075
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0038 0.0017 0.0137
Brugia malayi jmjC domain containing protein 0.0056 0.0039 0.0273
Echinococcus multilocularis glycine receptor subunit beta 0.005 0.0032 0.0032
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.005 0.0032 0.0032
Brugia malayi Cathepsin L-like precursor 0.005 0.0032 0.0225
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.005 0.0032 0.0289
Echinococcus multilocularis Niemann Pick C1 protein 0.0199 0.021 0.021
Loa Loa (eye worm) hypothetical protein 0.0027 0.0005 0.0033
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0149 0.015 0.045
Onchocerca volvulus 0.03 0.0332 0.2988
Loa Loa (eye worm) glutathione reductase 0.0047 0.0029 0.0203
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0062 0.0047 0.0375
Loa Loa (eye worm) hypothetical protein 0.0034 0.0012 0.0086
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.003 0.0008 0.0058
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.005 0.0032 0.0226
Trypanosoma cruzi DNA topoisomerase IA, putative 0.0089 0.0078 0.0629
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0249 0.027 0.1885
Giardia lamblia PHD finger protein 15 0.003 0.0008 0.0093
Brugia malayi hypothetical protein 0.0034 0.0012 0.0086
Onchocerca volvulus Bile acid receptor homolog 0.003 0.0008 0.0075
Brugia malayi Papain family cysteine protease containing protein 0.0026 0.0003 0.0022
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0284 0.0312 0.2806
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0108 0.0102 0.0102
Leishmania major heat shock protein 83-1 0.0349 0.039 0.3131
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0925 0.108 0.753
Echinococcus granulosus nuclear receptor 2DBD gamma 0.003 0.0008 0.0008
Mycobacterium ulcerans hypothetical protein 0.0121 0.0117 0.035
Schistosoma mansoni heat shock protein 0.0349 0.039 0.039
Leishmania major protein kinase, putative 0.0062 0.0047 0.0375
Trichomonas vaginalis conserved hypothetical protein 0.0085 0.0074 0.0669
Echinococcus multilocularis expressed conserved protein 0.0187 0.0196 0.0196
Trichomonas vaginalis penicillin-binding protein, putative 0.0149 0.015 0.1351
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0149 0.015 0.015
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0035 0.0015 0.0044
Plasmodium falciparum cysteine proteinase falcipain 3 0.005 0.0032 0.0182
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.005 0.0032 0.0289
Schistosoma mansoni hypothetical protein 0.0082 0.0071 0.0071
Mycobacterium ulcerans two component system membrane associated sensor kinase 0.0108 0.0102 0.0305
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0035 0.0015 0.0044
Leishmania major heat shock protein 83-1 0.0349 0.039 0.3131
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0017 0.0154
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.005 0.0032 0.0032
Echinococcus granulosus tumor protein p63 0.2052 0.2429 0.2429
Schistosoma mansoni acetyl-CoA synthetase 0.0035 0.0015 0.0015
Echinococcus multilocularis acetylcholinesterase 0.0422 0.0477 0.0477
Echinococcus granulosus heat shock protein 75 kDa mitochondrial 0.0124 0.0121 0.0121
Schistosoma mansoni hypothetical protein 0.0249 0.027 0.027
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0191 0.0201 0.1612
Mycobacterium tuberculosis Probable two component sensor kinase 0.0108 0.0102 0.0305
Loa Loa (eye worm) beta-lactamase 0.0149 0.015 0.1047
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0064 0.0048 0.0336
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0071 0.0058 0.0058
Onchocerca volvulus 0.0071 0.0058 0.0518
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.005 0.0032 0.0226
Brugia malayi AMP-binding enzyme family protein 0.0121 0.0117 0.0813
Echinococcus multilocularis DNA topoisomerase 2 alpha 0.087 0.1014 0.1014
Echinococcus multilocularis neuropeptide receptor A26 0.0457 0.052 0.052
Trypanosoma brucei developmentally regulated phosphoprotein 0.0108 0.0102 0.0817
Loa Loa (eye worm) hypothetical protein 0.003 0.0008 0.0058
Leishmania major hypothetical protein, conserved 0.0149 0.015 0.1205
Loa Loa (eye worm) hypothetical protein 0.003 0.0008 0.0058
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0125 0.0122 0.0122
Brugia malayi AMP-binding enzyme family protein 0.0121 0.0117 0.0813
Trichomonas vaginalis D-aminoacylase, putative 0.0149 0.015 0.1351
Plasmodium vivax acetyl-CoA synthetase, putative 0.0035 0.0015 0.0072
Loa Loa (eye worm) hypothetical protein 0.0035 0.0015 0.0102
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0087 0.0076 0.0425
Entamoeba histolytica cysteine proteinase 2 0.0026 0.0003 0.003
Leishmania major heat shock protein 83-1 0.0349 0.039 0.3131
Echinococcus granulosus DNA topoisomerase 2 alpha 0.087 0.1014 0.1014
Plasmodium vivax DNA gyrase subunit A, putative 0.1364 0.1605 1
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0056 0.0039 0.0314
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0161 0.0165 0.0165
Brugia malayi cathepsin L-like precursor 0.0034 0.0012 0.0086
Leishmania major heat shock protein 83-1 0.0349 0.039 0.3131
Mycobacterium ulcerans DNA gyrase subunit A 0.1364 0.1605 0.4815
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0149 0.015 0.1047
Schistosoma mansoni transcription factor btf3 0.0034 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0061 0.0045 0.0315
Entamoeba histolytica 90 kDa heat shock protein, putative 0.0124 0.0121 0.1188
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0125 0.0122 0.0122
Loa Loa (eye worm) hypothetical protein 0.005 0.0032 0.0226
Loa Loa (eye worm) cytochrome P450 family protein 0.0083 0.0072 0.0503
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0035 0.0015 0.0117
Brugia malayi Cathepsin L-like precursor 0.005 0.0032 0.0225
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.005 0.0032 0.0226
Mycobacterium ulcerans acyl-CoA synthetase 0.0121 0.0117 0.035
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0191 0.0201 0.1612
Brugia malayi Cathepsin L-like precursor 0.005 0.0032 0.0225
Onchocerca volvulus 0.005 0.0032 0.0292
Trichomonas vaginalis endoplasmin, putative 0.0232 0.025 0.2251
Brugia malayi intermediate filament protein 0.0079 0.0066 0.0463
Onchocerca volvulus 0.0071 0.0058 0.0518
Echinococcus multilocularis rho GTPase activating protein 20 0.0089 0.0078 0.0078
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.005 0.0032 0.0289
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.009 0.0079 0.0079
Trypanosoma cruzi cysteine peptidase, putative 0.005 0.0032 0.0258
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.003 0.0008 0.0058
Loa Loa (eye worm) hypothetical protein 0.005 0.0032 0.0226
Brugia malayi Cation transporter family protein 0.005 0.0032 0.0226
Trypanosoma brucei DNA topoisomerase III, putative 0.0089 0.0078 0.0629
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0062 0.0047 0.0241
Entamoeba histolytica acyl-coA synthetase, putative 0.0121 0.0117 0.115
Brugia malayi PHD-finger family protein 0.003 0.0008 0.0058
Mycobacterium tuberculosis Probable oxidoreductase 0.012 0.0116 0.0349
Trypanosoma brucei trypanothione reductase 0.0047 0.0029 0.0232
Chlamydia trachomatis DNA gyrase subunit B 0.0988 0.1155 0.7057
Entamoeba histolytica hypothetical protein 0.0146 0.0147 0.1447
Plasmodium vivax DNA topoisomerase II, putative 0.087 0.1014 0.6311
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0191 0.0201 0.1612
Schistosoma mansoni serine/threonine protein kinase 0.0092 0.0082 0.0082
Brugia malayi Protein kinase domain containing protein 0.0092 0.0082 0.0571
Trypanosoma brucei heat shock protein, putative 0.0349 0.039 0.3131
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0038 0.0017 0.012
Toxoplasma gondii LsmAD domain-containing protein 0.0052 0.0034 0.0164
Trypanosoma cruzi Heat shock protein 83, putative 0.0349 0.039 0.3131
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.005 0.0032 0.0289
Loa Loa (eye worm) hypothetical protein 0.0108 0.0102 0.071
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.003 0.0008 0.0008
Trypanosoma cruzi hypothetical protein, conserved 0.0149 0.015 0.1205
Leishmania major cysteine peptidase A (CPA) 0.005 0.0032 0.0258
Echinococcus multilocularis cathepsin l cysteine peptidase 0.005 0.0032 0.0032
Brugia malayi jmjC domain containing protein 0.0056 0.0039 0.0273
Schistosoma mansoni coup transcription factor 0.003 0.0008 0.0008
Brugia malayi Nuclear hormone receptor family member nhr-49 0.003 0.0008 0.0058
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0038 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0052 0.0034 0.024
Loa Loa (eye worm) hypothetical protein 0.0149 0.015 0.1047
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0046 0.0046
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.009 0.0079 0.0554
Mycobacterium leprae Probable two component sensor kinase MprB 0.0108 0.0102 0.0263
Brugia malayi Nuclear hormone receptor family member nhr-19 0.003 0.0008 0.0058
Schistosoma mansoni hypothetical protein 0.0109 0.0102 0.0102
Echinococcus granulosus Pyruvate dehydrogenase lipoamide kinase 0.0108 0.0102 0.0102
Trichomonas vaginalis CK1 family protein kinase 0.0039 0.0019 0.017
Echinococcus multilocularis dual specificity protein kinase clk2 0.0062 0.0047 0.0047
Echinococcus granulosus heat shock protein 90 0.0349 0.039 0.039
Loa Loa (eye worm) hypothetical protein 0.0136 0.0135 0.0945
Plasmodium falciparum DNA topoisomerase 2 0.087 0.1014 0.6311
Brugia malayi Cathepsin L-like precursor 0.005 0.0032 0.0225
Brugia malayi Cathepsin L-like precursor 0.005 0.0032 0.0225
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0039 0.0019 0.0152
Echinococcus granulosus dual specificity protein kinase clk2 0.0062 0.0047 0.0047
Loa Loa (eye worm) hypothetical protein 0.0077 0.0065 0.0452
Loa Loa (eye worm) DNA topoisomerase III beta-1 0.0089 0.0078 0.0547
Mycobacterium ulcerans beta-lactamase 0.0149 0.015 0.045
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0161 0.0165 0.0165
Plasmodium falciparum heat shock protein 90, putative 0.0124 0.0121 0.0733
Loa Loa (eye worm) hypothetical protein 0.0037 0.0016 0.0111
Mycobacterium tuberculosis Probable lipase LipD 0.0149 0.015 0.045
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.005 0.0032 0.0032
Leishmania major heat shock protein 83-1 0.0349 0.039 0.3131
Onchocerca volvulus 0.005 0.0032 0.0292
Schistosoma mansoni jumonji/arid domain-containing protein 0.0212 0.0226 0.0226
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0074 0.0061 0.0148
Entamoeba histolytica hypothetical protein 0.0027 0.0005 0.0045
Schistosoma mansoni jumonji/arid domain-containing protein 0.0212 0.0226 0.0226
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0031 0.0009 0.0026
Loa Loa (eye worm) hypothetical protein 0.0077 0.0065 0.0452
Echinococcus granulosus glycine receptor subunit beta 0.005 0.0032 0.0032
Loa Loa (eye worm) ACC-1 protein 0.005 0.0032 0.0226
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0161 0.0165 0.0811
Mycobacterium ulcerans acyl-CoA synthetase 0.0035 0.0015 0.0044
Echinococcus granulosus casein kinase I alpha 0.0039 0.0019 0.0019
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0035 0.0015 0.0015
Brugia malayi hypothetical protein 0.1221 0.1434 1
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0079 0.0066 0.0463
Brugia malayi Thioredoxin reductase 0.0047 0.0029 0.0203
Echinococcus granulosus cathepsin L cysteine proteinase 0.005 0.0032 0.0032
Echinococcus granulosus casein kinase I alpha 0.0039 0.0019 0.0019
Onchocerca volvulus 0.0035 0.0015 0.0132
Mycobacterium tuberculosis Conserved protein 0.0149 0.015 0.045
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0047 0.0029 0.0087
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0055 0.0038 0.0304
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0039 0.0019 0.0132
Echinococcus granulosus neuroligin 0.0071 0.0058 0.0058
Echinococcus granulosus acetylcholinesterase 0.0422 0.0477 0.0477
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.005 0.0032 0.0032
Echinococcus multilocularis lamin dm0 0.0079 0.0066 0.0066
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.005 0.0032 0.0226
Loa Loa (eye worm) hypothetical protein 0.0199 0.021 0.1467
Loa Loa (eye worm) hypothetical protein 0.0071 0.0058 0.0401
Mycobacterium tuberculosis Probable lipase LipE 0.0149 0.015 0.045
Onchocerca volvulus 0.005 0.0032 0.029
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0161 0.0165 0.0495
Trypanosoma cruzi transcription factor btf3, putative 0.0034 0.0013 0.0104
Loa Loa (eye worm) TAR-binding protein 0.0062 0.0046 0.0322
Onchocerca volvulus 0.0027 0.0005 0.0042
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.005 0.0032 0.0289
Mycobacterium ulcerans putative regultory protein 0.0108 0.0102 0.0305
Schistosoma mansoni DNA topoisomerase II 0.087 0.1014 0.1014
Entamoeba histolytica cysteine protease, putative 0.0026 0.0003 0.003
Loa Loa (eye worm) hypothetical protein 0.03 0.0332 0.2314
Onchocerca volvulus 0.005 0.0032 0.0292
Onchocerca volvulus Cathepsin L homolog 0.005 0.0032 0.029
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.005 0.0032 0.0289
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0038 0.0017 0.0017
Schistosoma mansoni patched 1 0.0085 0.0074 0.0074
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.003 0.0008 0.0008
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0035 0.0015 0.0044
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0026 0.0003 0.0027
Brugia malayi nuclear hormone receptor 0.003 0.0008 0.0058
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0836 0.0972 0.6782
Loa Loa (eye worm) RNA binding protein 0.0062 0.0046 0.0322
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0035 0.0015 0.0117
Schistosoma mansoni lipoxygenase 0.0118 0.0114 0.0114
Loa Loa (eye worm) hypothetical protein 0.0149 0.015 0.1047
Brugia malayi latrophilin 2 splice variant baaae 0.0101 0.0093 0.065
Trypanosoma cruzi cysteine proteinase, putative 0.0026 0.0003 0.0024
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.005 0.0032 0.0032
Echinococcus granulosus expressed conserved protein 0.0187 0.0196 0.0196
Trichomonas vaginalis D-aminoacylase, putative 0.0149 0.015 0.1351
Trypanosoma brucei heat shock protein, putative 0.0349 0.039 0.3131
Brugia malayi follicle stimulating hormone receptor 0.0925 0.108 0.753
Plasmodium falciparum basic transcription factor 3b, putative 0.0034 0.0013 0.0062
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0065 0.005 0.005
Loa Loa (eye worm) hypothetical protein 0.0027 0.0005 0.0033
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0062 0.0047 0.0375
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0071 0.0058 0.0517
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0149 0.015 0.045
Chlamydia trachomatis DNA gyrase subunit B 0.0795 0.0924 0.554
Loa Loa (eye worm) hypothetical protein 0.0119 0.0114 0.0796
Giardia lamblia Fructose-bisphosphate aldolase 0.0284 0.0312 0.3525
Echinococcus granulosus cysteine protease 0.0026 0.0003 0.0003
Echinococcus granulosus heat shock protein 90 0.0241 0.026 0.026
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.005 0.0032 0.0032
Mycobacterium ulcerans two component sensor kinase MprB 0.0108 0.0102 0.0305
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0174 0.0181 0.1452
Leishmania major heat shock protein, putative 0.0124 0.0121 0.0967
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.0108 0.0102 0.0916
Onchocerca volvulus Huntingtin homolog 0.0119 0.0114 0.1028
Onchocerca volvulus 0.005 0.0032 0.0292
Mycobacterium tuberculosis Probable reductase 0.0108 0.0102 0.0305
Brugia malayi Cytochrome P450 family protein 0.0083 0.0072 0.0503
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0035 0.0015 0.0072
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0023 0.0000098932 0.0000098932
Loa Loa (eye worm) hypothetical protein 0.0149 0.015 0.1047
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0035 0.0015 0.0143
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.009 0.008 0.0011
Echinococcus granulosus dna polymerase eta 0.0023 0.0000098932 0.0000098932
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0055 0.0038 0.0114
Echinococcus multilocularis cathepsin L cysteine protease 0.005 0.0032 0.0032
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0035 0.0015 0.0117
Echinococcus multilocularis glycine receptor subunit beta 0.005 0.0032 0.0032
Echinococcus granulosus lysine specific demethylase 5A 0.0212 0.0226 0.0226
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.005 0.0032 0.0032
Schistosoma mansoni aldehyde dehydrogenase 0.0179 0.0187 0.0187
Giardia lamblia Heat shock protein HSP 90-alpha 0.0241 0.026 0.2945
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0035 0.0015 0.0044
Plasmodium falciparum phd finger protein, putative 0.003 0.0008 0.0032
Echinococcus granulosus histone lysine methyltransferase setb 0.0136 0.0135 0.0135
Brugia malayi Bromodomain containing protein 0.008 0.0068 0.0473
Schistosoma mansoni hypothetical protein 0.0082 0.0071 0.0071
Toxoplasma gondii heat shock protein 90, putative 0.0349 0.039 0.2391
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0115 0.011 0.011
Loa Loa (eye worm) hypothetical protein 0.005 0.0032 0.0226
Treponema pallidum DNA gyrase, subunit B (gyrB) 0.0988 0.1155 0.7133
Echinococcus granulosus peptidase Clp S14 family 0.0106 0.0099 0.0099
Loa Loa (eye worm) cytochrome P450 family protein 0.0027 0.0005 0.0035
Plasmodium falciparum JmjC domain-containing protein, putative 0.0056 0.0039 0.0225
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0284 0.0312 0.2806
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0284 0.0312 0.2806
Echinococcus multilocularis JmjC domain containing protein 4 0.0056 0.0039 0.0039
Schistosoma mansoni inositol monophosphatase 0.0074 0.0061 0.0061
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.029 0.0319 0.0319
Giardia lamblia Pms1-like protein 0.0108 0.0102 0.115
Brugia malayi Nuclear hormone receptor family member nhr-19 0.003 0.0008 0.0058
Brugia malayi Cathepsin L-like precursor 0.005 0.0032 0.0225
Brugia malayi Protein kinase domain containing protein 0.0062 0.0047 0.0327
Echinococcus multilocularis cathepsin L cysteine protease 0.005 0.0032 0.0032
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.005 0.0032 0.0226
Echinococcus granulosus glycine receptor subunit alpha 1 0.005 0.0032 0.0032
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0035 0.0015 0.0044
Trypanosoma brucei heat shock protein 90, putative 0.0349 0.039 0.3131
Echinococcus granulosus lysine specific demethylase 6a 0.0056 0.0039 0.0039
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0136 0.0135 0.0135
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0062 0.0047 0.0327
Loa Loa (eye worm) hypothetical protein 0.005 0.0032 0.0226
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0035 0.0015 0.004
Leishmania major heat shock protein 83-1 0.0349 0.039 0.3131
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.012 0.0116 0.0307
Schistosoma mansoni neuroligin 3 (S09 family) 0.0071 0.0058 0.0058
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.012 0.0116 0.0116
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.012 0.0116 0.0116
Brugia malayi Nuclear hormone receptor family member nhr-1 0.003 0.0008 0.0058
Echinococcus multilocularis heat shock protein 75 kDa, mitochondrial 0.0124 0.0121 0.0121
Echinococcus multilocularis 0.0061 0.0045 0.0045
Loa Loa (eye worm) carboxylesterase 0.0071 0.0058 0.0401
Plasmodium falciparum histone acetyltransferase GCN5 0.0077 0.0065 0.0386
Trichomonas vaginalis heat shock protein, putative 0.0232 0.025 0.2251
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0039 0.0019 0.0132
Leishmania major heat shock protein 83-1 0.0349 0.039 0.3131
Loa Loa (eye worm) hypothetical protein 0.009 0.008 0.0559
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0071 0.0058 0.0172
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.005 0.0032 0.0289
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0199 0.021 0.2074
Loa Loa (eye worm) hypothetical protein 0.0079 0.0066 0.0463
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0087 0.0076 0.0456
Mycobacterium ulcerans acyl-CoA synthetase 0.0035 0.0015 0.0044
Loa Loa (eye worm) hypothetical protein 0.005 0.0032 0.0226
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.003 0.0008 0.0008
Echinococcus multilocularis cysteine protease 0.005 0.0032 0.0032
Treponema pallidum heat shock protein 90 0.0241 0.026 0.142
Brugia malayi hypothetical protein 0.0119 0.0114 0.0796
Trypanosoma brucei heat shock protein, putative 0.0349 0.039 0.3131
Schistosoma mansoni prokaryotic DNA topoisomerase 0.0089 0.0078 0.0078
Loa Loa (eye worm) hypothetical protein 0.0149 0.015 0.1047
Brugia malayi AMP-binding enzyme family protein 0.0035 0.0015 0.0102
Onchocerca volvulus 0.005 0.0032 0.029
Entamoeba histolytica casein kinase 1, putative 0.0039 0.0019 0.0186
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.005 0.0032 0.0226
Echinococcus granulosus DNA topoisomerase 3 alpha 0.0089 0.0078 0.0078
Loa Loa (eye worm) hypothetical protein 0.0071 0.0058 0.0401
Trypanosoma cruzi major cysteine proteinase, putative 0.015 0.0152 0.1219
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0071 0.0058 0.0058
Trichomonas vaginalis heat shock protein, putative 0.0241 0.026 0.2344
Schistosoma mansoni nAChR subunit 0.005 0.0032 0.0032
Leishmania major cathepsin L-like protease 0.005 0.0032 0.0258
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0038 0.0017 0.0017
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.005 0.0032 0.0289
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.005 0.0032 0.0289
Mycobacterium leprae Probable lipase LipE 0.0149 0.015 0.0409
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0013 0.0117
Entamoeba histolytica acetyltransferase, GNAT family 0.0077 0.0065 0.0639
Loa Loa (eye worm) hypothetical protein 0.009 0.008 0.0559
Echinococcus multilocularis casein kinase I alpha 0.0039 0.0019 0.0019
Brugia malayi Hsp90 protein 0.0124 0.0121 0.0841
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.003 0.0008 0.0058
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0064 0.0048 0.0144
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0074 0.0061 0.049
Loa Loa (eye worm) oxidoreductase 0.0035 0.0015 0.0102
Loa Loa (eye worm) hypothetical protein 0.1221 0.1434 1
Schistosoma mansoni pyruvate dehydrogenase 0.0108 0.0102 0.0102
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0241 0.026 0.0741
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0035 0.0015 0.0102
Mycobacterium ulcerans aldehyde dehydrogenase 0.0179 0.0187 0.0559
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.005 0.0032 0.0032
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0056 0.0039 0.0194
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0017 0.0154
Schistosoma mansoni ap endonuclease 0.0055 0.0038 0.0038
Mycobacterium tuberculosis Two component sensor histidine kinase DevS 0.0108 0.0102 0.0305
Loa Loa (eye worm) hypothetical protein 0.0105 0.0097 0.0679
Loa Loa (eye worm) hypothetical protein 0.0038 0.0017 0.012
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0092 0.0082 0.0656
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.005 0.0032 0.0289
Loa Loa (eye worm) cysteine protease 0.005 0.0032 0.0225
Entamoeba histolytica DNA topoisomerase III, putative 0.0089 0.0078 0.0773
Brugia malayi Cation transporter family protein 0.005 0.0032 0.0226
Echinococcus granulosus survival motor neuron protein 1 0.1221 0.1434 0.1434
Entamoeba histolytica acyl-CoA synthetase, putative 0.0121 0.0117 0.115
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0108 0.0102 0.0305
Entamoeba histolytica cysteine protease, putative 0.0026 0.0003 0.003
Onchocerca volvulus 0.0249 0.027 0.2434
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0241 0.026 0.142
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.003 0.0008 0.0075
Echinococcus granulosus intermediate filament protein 0.0079 0.0066 0.0066
Plasmodium vivax glutathione reductase, putative 0.0047 0.0029 0.0162
Entamoeba histolytica cysteine proteinase, putative 0.005 0.0032 0.0317
Plasmodium vivax SET domain protein, putative 0.012 0.0116 0.0703
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0062 0.0047 0.0375
Loa Loa (eye worm) hypothetical protein 0.0071 0.0058 0.0401
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0035 0.0015 0.0044
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0017 0.0154
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0055 0.0039 0.0072
Mycobacterium ulcerans carboxylesterase, LipT 0.0071 0.0058 0.0172
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0149 0.015 0.015
Brugia malayi jmjC domain containing protein 0.0272 0.0298 0.2078
Brugia malayi Inositol-1 0.0074 0.0061 0.0426
Mycobacterium leprae Probable DNA topoisomerase I TopA (omega-protein) (relaxing enzyme) (untwisting enzyme) (swivelase) (type I DNA topoisomerase) ( 0.0089 0.0078 0.0192
Trypanosoma brucei Heat shock protein 83, putative 0.0349 0.039 0.3131
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0108 0.0102 0.0305
Toxoplasma gondii Hsp90 domain-containing protein 0.0124 0.0121 0.0703
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0064 0.0048 0.0144
Brugia malayi Latrophilin receptor protein 2 0.0047 0.0028 0.0197
Echinococcus granulosus inositol monophosphatase 1 0.0074 0.0061 0.0061
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.003 0.0008 0.0008
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.005 0.0032 0.0289
Leishmania major protein kinase, putative 0.0062 0.0047 0.0375
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0064 0.0048 0.0048
Echinococcus granulosus casein kinase I delta 0.0039 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.003 0.0008 0.0058
Plasmodium falciparum endoplasmin, putative 0.0232 0.025 0.1542
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0241 0.026 0.026
Echinococcus granulosus neuropeptide s receptor 0.0457 0.052 0.052
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0038 0.0017 0.0137
Plasmodium falciparum protein serine/threonine kinase-1 0.0062 0.0047 0.0273
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0064 0.0048 0.0048
Mycobacterium leprae Probable two-component sensor kinase 0.0108 0.0102 0.0263
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.003 0.0008 0.0008
Trypanosoma cruzi DNA topoisomerase IA, putative 0.0089 0.0078 0.0629
Trypanosoma brucei heat shock protein, putative 0.0349 0.039 0.3131
Loa Loa (eye worm) hypothetical protein 0.0047 0.0028 0.0197
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0046 0.0046
Loa Loa (eye worm) hypothetical protein 0.0027 0.0005 0.0033
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0027 0.0005 0.0005
Echinococcus granulosus peregrin 0.0039 0.0019 0.0019
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0058 0.0041 0.0041
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.005 0.0032 0.0289
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.003 0.0008 0.0058
Giardia lamblia Heat shock protein HSP 90-alpha 0.0349 0.039 0.441
Loa Loa (eye worm) inositol-1 0.0074 0.0061 0.0426
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0035 0.0015 0.0117
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0062 0.0047 0.0375
Trypanosoma cruzi DNA topoisomerase II, putative 0.0781 0.0908 0.7287
Brugia malayi Endoplasmin precursor 0.0349 0.039 0.272
Loa Loa (eye worm) jmjC domain-containing protein 0.0056 0.0039 0.0273
Trypanosoma cruzi hypothetical protein, conserved 0.0149 0.015 0.1205
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0074 0.0061 0.0549
Echinococcus multilocularis ecdysone induced protein 78C 0.003 0.0008 0.0008
Leishmania major acetyl-CoA synthetase, putative 0.0035 0.0015 0.0117
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0149 0.015 0.045
Onchocerca volvulus 0.005 0.0032 0.029
Mycobacterium tuberculosis Possible penicillin-binding protein 0.095 0.1109 0.3328
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.005 0.0032 0.0289
Plasmodium falciparum heat shock protein 90 0.0349 0.039 0.2416
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.009 0.0079 0.0079
Mycobacterium ulcerans DNA topoisomerase I 0.0089 0.0078 0.0235
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0106 0.0099 0.0296
Echinococcus granulosus histone acetyltransferase KAT2B 0.0087 0.0076 0.0076
Echinococcus granulosus jumonji domain containing protein 0.0042 0.0022 0.0022
Leishmania major heat shock protein 83-1 0.0349 0.039 0.3131
Echinococcus granulosus ecdysone induced protein 78C 0.003 0.0008 0.0008
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0139 0.0138 0.0372
Mycobacterium ulcerans two component sensor histidine kinase TrcS 0.0108 0.0102 0.0305
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0027 0.0005 0.0033
Loa Loa (eye worm) ICD-1 protein 0.0034 0.0013 0.0091
Entamoeba histolytica transcription factor BTF3, putative 0.0034 0.0013 0.0128
Trypanosoma cruzi heat shock protein 90, putative 0.0225 0.0242 0.194
Leishmania major heat shock protein 83-1 0.0349 0.039 0.3131
Schistosoma mansoni serine/threonine protein kinase 0.0062 0.0047 0.0047
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.005 0.0032 0.0289
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.005 0.0032 0.0226
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0146 0.0147 0.0147
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0013 0.0117
Loa Loa (eye worm) hypothetical protein 0.0027 0.0005 0.0033
Loa Loa (eye worm) hypothetical protein 0.009 0.008 0.0559
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0035 0.0015 0.0044
Echinococcus multilocularis jumonji domain containing 1A 0.0056 0.0039 0.0039
Entamoeba histolytica hypothetical protein 0.0092 0.0082 0.0806
Echinococcus multilocularis muscleblind protein 1 0.0302 0.0334 0.0334
Trypanosoma brucei DNA topoisomerase II alpha, putative 0.0781 0.0908 0.7287
Brugia malayi heat shock protein 90 0.0349 0.039 0.272
Onchocerca volvulus Heat shock protein 75 kDa, mitochondrial homolog 0.0124 0.0121 0.1085
Brugia malayi Carboxylesterase family protein 0.0071 0.0058 0.0401
Schistosoma mansoni cathepsin F (C01 family) 0.0034 0.0012 0.0012
Trichomonas vaginalis set domain proteins, putative 0.0951 0.1111 1
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0056 0.0039 0.0314
Echinococcus multilocularis dual specificity 0.0092 0.0082 0.0082
Echinococcus granulosus glycine receptor subunit alpha 1 0.005 0.0032 0.0032
Schistosoma mansoni bromodomain containing protein 0.0068 0.0054 0.0054
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0108 0.0102 0.0305
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0038 0.0017 0.0017
Echinococcus multilocularis protein patched 0.0085 0.0074 0.0074
Mycobacterium ulcerans AcrR family transcriptional regulator 0.2807 0.3332 1
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0035 0.0015 0.0044
Plasmodium vivax vivapain-2 0.005 0.0032 0.0182
Mycobacterium leprae Probable transcriptional regulatory repressor protein (TetR-family) EthR 0.2807 0.3332 1
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.0108 0.0102 0.0916
Loa Loa (eye worm) jmjC domain-containing protein 0.0062 0.0047 0.0326
Leishmania major DNA topoisomerase III, putative 0.0089 0.0078 0.0629
Plasmodium vivax hypothetical protein, conserved 0.0108 0.0102 0.0616
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0023 0.0000098932 0.0000098932
Echinococcus multilocularis glycine receptor subunit alpha 1 0.005 0.0032 0.0032
Trichomonas vaginalis heat shock protein, putative 0.0124 0.0121 0.1084
Schistosoma mansoni neurotransmitter gated ion channel 0.0027 0.0005 0.0005
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0026 0.0003 0.0003
Trypanosoma brucei heat shock protein 84, putative 0.0124 0.0121 0.0967
Entamoeba histolytica cysteine protease, putative 0.0026 0.0003 0.003
Echinococcus multilocularis geminin 0.0502 0.0573 0.0573
Onchocerca volvulus 0.005 0.0032 0.0292
Echinococcus multilocularis survival motor neuron protein 1 0.1221 0.1434 0.1434
Mycobacterium leprae conserved hypothetical protein 0.0149 0.015 0.0409
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0064 0.0048 0.0387
Schistosoma mansoni hypothetical protein 0.0082 0.0071 0.0071
Trypanosoma cruzi cysteine proteinase, putative 0.0026 0.0003 0.0024
Giardia lamblia DNA topoisomerase II 0.0762 0.0884 1
Leishmania major heat shock protein 83-1 0.0349 0.039 0.3131
Echinococcus granulosus cathepsin l cysteine peptidase 0.005 0.0032 0.0032
Trypanosoma cruzi cytochrome P450, putative 0.0027 0.0005 0.004
Echinococcus granulosus glycine receptor subunit alpha 1 0.005 0.0032 0.0032
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0118 0.0114 0.0114
Echinococcus granulosus neuropeptide receptor A26 0.0457 0.052 0.052
Schistosoma mansoni nAChR subunit 0.005 0.0032 0.0032
Mycobacterium ulcerans acyl-CoA synthetase 0.0035 0.0015 0.0044
Echinococcus multilocularis tar DNA binding protein 0.0062 0.0046 0.0046
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0027 0.0005 0.0033
Plasmodium falciparum DNA gyrase subunit B 0.0988 0.1155 0.7195
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0026 0.0003 0.0027
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0035 0.0015 0.0044
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0055 0.0039 0.0004
Loa Loa (eye worm) jmjC domain-containing protein 0.0212 0.0226 0.1574
Loa Loa (eye worm) hypothetical protein 0.005 0.0032 0.0226
Treponema pallidum DNA gyrase, subunit A (gyrA) 0.1364 0.1605 1
Echinococcus multilocularis para nitrobenzyl esterase 0.0071 0.0058 0.0058
Mycobacterium tuberculosis Two component sensor histidine kinase PrrB 0.0108 0.0102 0.0305
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0026 0.0003 0.0003
Entamoeba histolytica cysteine protease, putative 0.0026 0.0003 0.003
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0035 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.038 0.0427 0.298
Entamoeba histolytica casein kinase, putative 0.0039 0.0019 0.0186
Trypanosoma cruzi trypanothione reductase, putative 0.0047 0.0029 0.0232
Mycobacterium ulcerans heat shock protein 90 0.0241 0.026 0.0781
Onchocerca volvulus 0.0035 0.0015 0.0132
Echinococcus granulosus muscleblind protein 0.0302 0.0334 0.0334
Echinococcus granulosus hypothetical protein 0.0061 0.0045 0.0045
Echinococcus granulosus PHD finger protein rhinoceros 0.003 0.0008 0.0008
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0027 0.0005 0.0015
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0071 0.0058 0.0058
Loa Loa (eye worm) hypothetical protein 0.0034 0.0012 0.0086
Mycobacterium tuberculosis Probable sensor protein KdpD 0.0108 0.0102 0.0305
Loa Loa (eye worm) hypothetical protein 0.0085 0.0074 0.0519
Echinococcus multilocularis FTZ F1 alpha 0.003 0.0008 0.0008
Echinococcus multilocularis nAChR subunit 0.005 0.0032 0.0032
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0085 0.0074 0.0222
Entamoeba histolytica cysteine protease, putative 0.0026 0.0003 0.003
Brugia malayi Pre-SET motif family protein 0.0836 0.0972 0.6782
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0055 0.0039 0.0222
Echinococcus multilocularis muscleblind protein 0.0302 0.0334 0.0334
Brugia malayi Cytochrome P450 family protein 0.0027 0.0005 0.0035
Echinococcus multilocularis carboxylesterase 5A 0.0422 0.0477 0.0477
Brugia malayi steroid hormone receptor 0.003 0.0008 0.0058
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0272 0.0298 0.0298
Trypanosoma brucei PAB1-binding protein , putative 0.0052 0.0034 0.0276
Brugia malayi Nuclear hormone receptor family member nhr-3 0.003 0.0008 0.0058
Plasmodium vivax heat shock protein 86, putative 0.0349 0.039 0.2416
Loa Loa (eye worm) hypothetical protein 0.0148 0.0149 0.1041
Echinococcus granulosus jumonji domain containing 1A 0.0056 0.0039 0.0039
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0035 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0422 0.0477 0.3328
Toxoplasma gondii DNA topoisomerase 2, putative 0.087 0.1014 0.6299
Brugia malayi Steroid receptor seven-up type 2 0.003 0.0008 0.0058
Entamoeba histolytica cysteine proteinase, putative 0.0034 0.0012 0.0121
Loa Loa (eye worm) acetylcholinesterase 1 0.0422 0.0477 0.3328
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0149 0.015 0.1047
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.005 0.0032 0.0032
Mycobacterium tuberculosis DNA gyrase (subunit A) GyrA (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.1364 0.1605 0.4815
Schistosoma mansoni lamin 0.0079 0.0066 0.0066
Echinococcus multilocularis phd:f box containing protein 0.0056 0.0039 0.0039
Trypanosoma cruzi heat shock protein 85, putative 0.0349 0.039 0.3131
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0148 0.0149 0.1041
Leishmania major cathepsin L-like protease 0.005 0.0032 0.0258
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0055 0.0038 0.0304
Echinococcus granulosus tar DNA binding protein 0.0062 0.0046 0.0046
Echinococcus granulosus transcription factor btf3 0.0034 0.0013 0.0013
Schistosoma mansoni zinc finger protein 0.0026 0.0003 0.0003
Entamoeba histolytica cysteine protease, putative 0.0026 0.0003 0.003
Trypanosoma cruzi cruzipain precursor, putative 0.0191 0.0201 0.1612
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0038 0.0018 0.0018
Trichomonas vaginalis spcc417.12 protein, putative 0.0071 0.0058 0.0517
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.005 0.0032 0.0032
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.003 0.0008 0.0008
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0042 0.0023 0.0158
Loa Loa (eye worm) hypothetical protein 0.005 0.0032 0.0226
Loa Loa (eye worm) GABA receptor subunit 0.0027 0.0005 0.0033
Onchocerca volvulus 0.0089 0.0078 0.0706
Treponema pallidum fructose-bisphosphate aldolase 0.0284 0.0312 0.1748
Loa Loa (eye worm) hypothetical protein 0.0149 0.015 0.1047
Echinococcus multilocularis casein kinase I delta 0.0039 0.0019 0.0019
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0241 0.026 0.0781
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0035 0.0015 0.004
Loa Loa (eye worm) hypothetical protein 0.005 0.0032 0.0226
Loa Loa (eye worm) hypothetical protein 0.0071 0.0058 0.0401
Wolbachia endosymbiont of Brugia malayi DNA gyrase subunit A 0.1364 0.1605 1
Trypanosoma cruzi cysteine protease, putative 0.0026 0.0003 0.0024
Toxoplasma gondii casein kinase I 0.0039 0.0019 0.0067
Loa Loa (eye worm) hypothetical protein 0.0027 0.0005 0.0033
Brugia malayi Cation transporter family protein 0.005 0.0032 0.0226
Giardia lamblia DNA topoisomerase III 0.0089 0.0078 0.0886
Loa Loa (eye worm) hypothetical protein 0.003 0.0008 0.0058
Trypanosoma brucei casein kinase I, isoform 2 0.0039 0.0019 0.0152
Echinococcus granulosus cathepsin l1 0.0034 0.0012 0.0012
Schistosoma mansoni hypothetical protein 0.0047 0.0028 0.0028
Plasmodium vivax serine/threonine kinase-1, putative 0.0062 0.0047 0.0273
Loa Loa (eye worm) hypothetical protein 0.0422 0.0477 0.3328
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0108 0.0102 0.0586
Onchocerca volvulus 0.0034 0.0012 0.0111
Schistosoma mansoni lamin 0.0079 0.0066 0.0066
Echinococcus granulosus phd:f box containing protein 0.0056 0.0039 0.0039
Loa Loa (eye worm) hypothetical protein 0.0071 0.0058 0.0401
Onchocerca volvulus Huntingtin homolog 0.0119 0.0114 0.1028
Trypanosoma cruzi cysteine peptidase, putative 0.0191 0.0201 0.1612
Echinococcus granulosus zinc finger protein 0.0026 0.0003 0.0003
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.005 0.0032 0.0032
Loa Loa (eye worm) ctsf protein 0.005 0.0032 0.0225
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0121 0.0117 0.035
Toxoplasma gondii cathepsin CPL 0.005 0.0032 0.015
Mycobacterium tuberculosis Two component sensor kinase MprB 0.0108 0.0102 0.0305
Onchocerca volvulus 0.0149 0.015 0.1352
Entamoeba histolytica cysteine proteinase, putative 0.0026 0.0003 0.003
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.005 0.0032 0.0032
Echinococcus granulosus cathepsin l1 0.005 0.0032 0.0032
Trypanosoma cruzi DNA topoisomerase II, putative 0.0781 0.0908 0.7287
Brugia malayi Muscleblind-like protein 0.0302 0.0334 0.2328
Brugia malayi AMP-binding enzyme family protein 0.0035 0.0015 0.0102
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0731 0.0847 0.7624
Brugia malayi DNA topoisomerase III 0.0089 0.0078 0.0547
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0284 0.0312 0.2806
Loa Loa (eye worm) steroid hormone receptor 0.003 0.0008 0.0058
Loa Loa (eye worm) hypothetical protein 0.005 0.0032 0.0226
Echinococcus granulosus ubiquitin specific protease 41 0.0038 0.0017 0.0017
Echinococcus multilocularis GPCR, family 2 0.0047 0.0028 0.0028
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0038 0.0017 0.0138
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0013 0.0117
Leishmania major cathepsin L-like protease 0.0191 0.0201 0.1612
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.005 0.0032 0.0032
Mycobacterium tuberculosis Conserved protein 0.0149 0.015 0.045
Trypanosoma cruzi heat shock protein 85, putative 0.0349 0.039 0.3131
Schistosoma mansoni intermediate filament proteins 0.0079 0.0066 0.0066
Echinococcus multilocularis casein kinase I delta 0.0039 0.0019 0.0019
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0092 0.0082 0.0656
Leishmania major 4-coumarate:coa ligase-like protein 0.0121 0.0117 0.0936
Trichomonas vaginalis inositol monophosphatase, putative 0.0074 0.0061 0.0549
Echinococcus multilocularis lysine specific demethylase 6a 0.0056 0.0039 0.0039
Leishmania major cytochrome p450-like protein 0.0027 0.0005 0.004
Onchocerca volvulus 0.012 0.0116 0.1041
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0026 0.0003 0.0024
Echinococcus multilocularis casein kinase I alpha 0.0039 0.0019 0.0019
Schistosoma mansoni microtubule-associated protein tau 0.8376 1 1
Trypanosoma cruzi PAB1-binding protein , putative 0.0052 0.0034 0.0276
Schistosoma mansoni hypothetical protein 0.0101 0.0093 0.0093
Brugia malayi Cathepsin L-like precursor 0.0034 0.0012 0.0086
Onchocerca volvulus 0.0071 0.0058 0.0518
Mycobacterium tuberculosis Two component sensory transduction histidine kinase MtrB 0.0108 0.0102 0.0305
Schistosoma mansoni BC026374 protein (S09 family) 0.0071 0.0058 0.0058
Mycobacterium tuberculosis DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.0988 0.1155 0.3467
Leishmania major cathepsin L-like protease 0.005 0.0032 0.0258
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.003 0.0008 0.0058
Loa Loa (eye worm) hypothetical protein 0.0037 0.0017 0.0117
Leishmania major basic transcription factor 3a, putative 0.0034 0.0013 0.0104
Loa Loa (eye worm) hypothetical protein 0.009 0.008 0.0559
Schistosoma mansoni retinoic acid receptor RXR 0.003 0.0008 0.0008
Loa Loa (eye worm) latrophilin receptor protein 2 0.0047 0.0028 0.0197
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0055 0.0038 0.0114
Schistosoma mansoni thyroid hormone receptor 0.0155 0.0158 0.0158
Entamoeba histolytica DNA topoisomerase III, putative 0.0089 0.0078 0.0773
Mycobacterium tuberculosis Conserved protein 0.0149 0.015 0.045
Toxoplasma gondii aldehyde dehydrogenase 0.0179 0.0187 0.1116
Toxoplasma gondii NAC domain-containing protein 0.0034 0.0013 0.003
Entamoeba histolytica protein kinase, putative 0.0092 0.0082 0.0806
Giardia lamblia Grp94/Hsp90 0.0241 0.026 0.2945
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0035 0.0014 0.0014
Mycobacterium ulcerans two component sensor histidine kinase PrrB 0.0108 0.0102 0.0305
Brugia malayi Bromodomain containing protein 0.0039 0.0019 0.0136
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0064 0.0048 0.0144
Trypanosoma brucei heat shock protein, putative 0.0349 0.039 0.3131
Echinococcus granulosus Protein patched homolog 1 0.0085 0.0074 0.0074
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0035 0.0015 0.0044
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0662 0.0765 0.4741
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0055 0.0038 0.0038
Brugia malayi hypothetical protein 0.0052 0.0034 0.024
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0161 0.0165 0.1011
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0202 0.0214 0.0214
Brugia malayi DNA topoisomerase II, alpha isozyme 0.087 0.1014 0.7071
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0035 0.0015 0.0044
Echinococcus multilocularis neuropeptide s receptor 0.0457 0.052 0.052
Trypanosoma cruzi heat shock protein 85, putative 0.0349 0.039 0.3131
Loa Loa (eye worm) hypothetical protein 0.005 0.0032 0.0226
Echinococcus granulosus cathepsin L cysteine protease 0.0026 0.0003 0.0003
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.005 0.0032 0.0289
Schistosoma mansoni aldehyde dehydrogenase 0.0179 0.0187 0.0187
Loa Loa (eye worm) hypothetical protein 0.005 0.0032 0.0226
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0121 0.0117 0.035
Echinococcus granulosus heat shock protein 0.0349 0.039 0.039
Trypanosoma cruzi casein kinase, putative 0.0039 0.0019 0.0152
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0139 0.0138 0.0414
Brugia malayi casein kinase I 0.0039 0.0019 0.0132
Brugia malayi DNA gyrase/topoisomerase IV, A subunit family protein 0.087 0.1014 0.7071
Echinococcus granulosus Niemann Pick C1 protein 0.0199 0.021 0.021
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0241 0.026 0.2091
Loa Loa (eye worm) hypothetical protein 0.003 0.0008 0.0058
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0092 0.0082 0.0571
Echinococcus granulosus carboxylesterase 5A 0.0422 0.0477 0.0477
Entamoeba histolytica cysteine protease, putative 0.0026 0.0003 0.003
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0284 0.0312 0.2806
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.005 0.0032 0.0289
Loa Loa (eye worm) hypothetical protein 0.0071 0.0058 0.0401
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0047 0.0028 0.0197
Chlamydia trachomatis DNA gyrase subunit A 0.1364 0.1605 1
Toxoplasma gondii DNA gyrase/topoisomerase IV, A subunit domain-containing protein 0.1364 0.1605 1
Leishmania major cathepsin L-like protease 0.0191 0.0201 0.1612
Trypanosoma cruzi DNA topoisomerase III, putative 0.0089 0.0078 0.0629
Mycobacterium tuberculosis Possible two component system response sensor kinase membrane associated PhoR 0.0108 0.0102 0.0305
Schistosoma mansoni hypothetical protein 0.0047 0.0028 0.0028
Trypanosoma cruzi cysteine peptidase, putative 0.0026 0.0003 0.0024
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0047 0.0028 0.0028
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0038 0.0017 0.0168
Schistosoma mansoni serine/threonine protein kinase 0.0039 0.0019 0.0019
Plasmodium falciparum ataxin-2 like protein, putative 0.0052 0.0034 0.0196
Loa Loa (eye worm) hypothetical protein 0.0071 0.0058 0.0401
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.003 0.0008 0.0058
Echinococcus multilocularis microtubule associated protein 2 0.8376 1 1
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0074 0.0061 0.0549
Echinococcus multilocularis protein dispatched 1 0.0097 0.0089 0.0089
Entamoeba histolytica cysteine proteinase, putative 0.0026 0.0003 0.003
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0035 0.0015 0.0044
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.005 0.0032 0.0226
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0161 0.0165 0.1011
Schistosoma mansoni transcription factor LCR-F1 0.0146 0.0147 0.0147
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0074 0.0061 0.049
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0056 0.0039 0.0314
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0035 0.0015 0.0102
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0026 0.0003 0.0003
Trypanosoma cruzi transcription factor btf3, putative 0.0034 0.0013 0.0104
Schistosoma mansoni nAChR subunit 0.005 0.0032 0.0032
Onchocerca volvulus 0.005 0.0032 0.029
Schistosoma mansoni hypothetical protein 0.0047 0.0028 0.0028
Schistosoma mansoni heat shock protein 0.0349 0.039 0.039
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.005 0.0032 0.0226
Loa Loa (eye worm) hypothetical protein 0.0048 0.003 0.021
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0023 0.0000098932 0.0001
Brugia malayi ImpB/MucB/SamB family protein 0.0023 0.0000098932 0.0001
Schistosoma mansoni peptidase Clp (S14 family) 0.0161 0.0165 0.0165
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.009 0.0079 0.0079
Mycobacterium ulcerans two component system response phosphate sensor kinase, PhoR 0.0108 0.0102 0.0305
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0055 0.0038 0.0218
Loa Loa (eye worm) hypothetical protein 0.0098 0.0089 0.0624
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.005 0.0032 0.0226
Echinococcus multilocularis glycine receptor subunit alpha 1 0.005 0.0032 0.0032
Leishmania major acetyl-CoA synthetase, putative 0.0035 0.0015 0.0117
Trypanosoma brucei hypothetical protein, conserved 0.0149 0.015 0.1205
Mycobacterium ulcerans acyl-CoA synthetase 0.0121 0.0117 0.035
Schistosoma mansoni ap endonuclease 0.0055 0.0038 0.0038
Onchocerca volvulus 0.0071 0.0058 0.0518
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.012 0.0116 0.0673
Leishmania major DNA topoisomerase III, putative 0.0089 0.0078 0.0629
Brugia malayi DNA topoisomerase III beta-1 0.0089 0.0078 0.0547
Echinococcus granulosus glycine receptor subunit beta 0.005 0.0032 0.0032
Plasmodium vivax hypothetical protein, conserved 0.0149 0.015 0.0918
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0027 0.0005 0.0005
Onchocerca volvulus 0.0047 0.0028 0.0253
Entamoeba histolytica cysteine proteinase, putative 0.005 0.0032 0.0317
Plasmodium vivax hypothetical protein, conserved 0.003 0.0008 0.0032
Schistosoma mansoni DNA polymerase eta 0.0023 0.0000098932 0.0000098932
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0027 0.0005 0.0033
Wolbachia endosymbiont of Brugia malayi topoisomerase IA, TopA 0.0089 0.0078 0.0258
Loa Loa (eye worm) hypothetical protein 0.005 0.0032 0.0226
Trichomonas vaginalis prokaryotic DNA topoisomerase, putative 0.0089 0.0078 0.0705
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0056 0.0039 0.0039
Schistosoma mansoni phosphatidylserine receptor 0.0056 0.0039 0.0039
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0087 0.0076 0.0425
Giardia lamblia Kinase, CK1 Casein kinase 0.0039 0.0019 0.0213
Schistosoma mansoni hypothetical protein 0.0502 0.0573 0.0573
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.012 0.0116 0.0349
Brugia malayi Cathepsin L-like precursor 0.0034 0.0012 0.0086
Echinococcus multilocularis musashi 0.0079 0.0066 0.0066
Onchocerca volvulus 0.0079 0.0066 0.0598
Loa Loa (eye worm) fibroinase 0.005 0.0032 0.0225
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.005 0.0032 0.0289
Brugia malayi Carboxylesterase family protein 0.0071 0.0058 0.0401
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.003 0.0008 0.0058
Loa Loa (eye worm) hypothetical protein 0.0035 0.0015 0.0102
Mycobacterium tuberculosis Two component sensor histidine kinase TrcS 0.0108 0.0102 0.0305
Loa Loa (eye worm) papain family cysteine protease containing protein 0.005 0.0032 0.0225
Trichomonas vaginalis bromodomain-containing protein, putative 0.0087 0.0076 0.0684
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0074 0.0061 0.0183
Entamoeba histolytica hypothetical protein 0.0034 0.0013 0.0128
Loa Loa (eye worm) ACC-1 protein 0.005 0.0032 0.0226
Loa Loa (eye worm) hypothetical protein 0.038 0.0427 0.298
Trypanosoma brucei heat shock protein 90, putative 0.0349 0.039 0.3131
Plasmodium vivax basic transcription factor 3b, putative 0.0034 0.0013 0.0062
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0035 0.0015 0.0117
Brugia malayi acetyltransferase, GNAT family protein 0.029 0.0319 0.2224
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0071 0.0058 0.0058
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0087 0.0076 0.0684
Onchocerca volvulus 0.0035 0.0015 0.0132
Onchocerca volvulus 0.005 0.0032 0.0292
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.005 0.0032 0.0032
Schistosoma mansoni lipoxygenase 0.0083 0.0071 0.0071
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0121 0.0117 0.035
Plasmodium vivax heat shock protein 90, putative 0.0124 0.0121 0.0733
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0191 0.0201 0.1612
Loa Loa (eye worm) hypothetical protein 0.003 0.0008 0.0058
Onchocerca volvulus Putative nachr subunit 0.005 0.0032 0.0292
Loa Loa (eye worm) cytochrome P450 family protein 0.0027 0.0005 0.0035
Schistosoma mansoni prokaryotic DNA topoisomerase 0.0089 0.0078 0.0078
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.005 0.0032 0.0289
Loa Loa (eye worm) hypothetical protein 0.0027 0.0005 0.0033
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0026 0.0003 0.0024
Brugia malayi Papain family cysteine protease containing protein 0.005 0.0032 0.0225
Onchocerca volvulus 0.0079 0.0066 0.0598
Echinococcus multilocularis tumor protein p63 0.2052 0.2429 0.2429
Toxoplasma gondii heat shock protein 75, putative 0.0124 0.0121 0.0703
Trypanosoma cruzi heat shock protein, putative 0.0124 0.0121 0.0967
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.003 0.0008 0.0008
Entamoeba histolytica cysteine protease, putative 0.0026 0.0003 0.003
Loa Loa (eye worm) jmjC domain-containing protein 0.0056 0.0039 0.0273
Loa Loa (eye worm) acetyltransferase 0.029 0.0319 0.2224
Schistosoma mansoni survival motor neuron protein 0.0249 0.027 0.027
Echinococcus granulosus para nitrobenzyl esterase 0.0071 0.0058 0.0058
Echinococcus granulosus nuclear receptor 2DBD gamma 0.003 0.0008 0.0008
Brugia malayi Pre-SET motif family protein 0.012 0.0116 0.0807
Trypanosoma brucei DNA topoisomerase III, putative 0.0089 0.0078 0.0629
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0085 0.0074 0.0222
Mycobacterium ulcerans two component sensor histidine kinase SenX3 0.0108 0.0102 0.0305
Loa Loa (eye worm) heat shock protein 90 0.0349 0.039 0.272
Schistosoma mansoni cathepsin F (C01 family) 0.005 0.0032 0.0032
Entamoeba histolytica cysteine protease, putative 0.0026 0.0003 0.003
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0066 0.0052 0.0112
Brugia malayi nuclear receptor NHR-88 0.003 0.0008 0.0058
Plasmodium vivax thioredoxin reductase, putative 0.0047 0.0029 0.0162
Schistosoma mansoni Tr4/Tr2 (homologue) 0.003 0.0008 0.0008
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0108 0.0102 0.0153
Echinococcus granulosus geminin 0.0502 0.0573 0.0573
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.005 0.0032 0.0226
Loa Loa (eye worm) hypothetical protein 0.0038 0.0018 0.0123
Trichomonas vaginalis heat shock protein, putative 0.0349 0.039 0.3511
Trichomonas vaginalis receptor histidine kinase, putative 0.0108 0.0102 0.0916
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0085 0.0074 0.0519
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0062 0.0046 0.0322
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.003 0.0008 0.0058
Trichomonas vaginalis antibiotic synthetase, putative 0.0035 0.0015 0.0131
Mycobacterium ulcerans aldehyde dehydrogenase 0.0179 0.0187 0.0559
Schistosoma mansoni cathepsin F (C01 family) 0.005 0.0032 0.0032
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.1064 0.1245 1
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0055 0.0038 0.0038
Brugia malayi Probable ClpP-like protease 0.0161 0.0165 0.1151
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.029 0.0319 0.0319
Plasmodium falciparum acyl-CoA synthetase 0.009 0.008 0.0481
Trichomonas vaginalis ap endonuclease, putative 0.0055 0.0038 0.0341
Onchocerca volvulus 0.005 0.0032 0.029
Giardia lamblia Kinase, CMGC CLK 0.0062 0.0047 0.0528
Echinococcus multilocularis peregrin 0.0039 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.0302 0.0334 0.2328
Schistosoma mansoni retinoid-x-receptor (RXR) 0.003 0.0008 0.0008
Plasmodium vivax vivapain-2 0.005 0.0032 0.0182
Trichomonas vaginalis receptor histidine kinase, putative 0.0108 0.0102 0.0916
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0121 0.0117 0.035
Loa Loa (eye worm) hypothetical protein 0.0479 0.0545 0.3802
Loa Loa (eye worm) hypothetical protein 0.0027 0.0005 0.0033
Entamoeba histolytica cysteine protease, putative 0.0026 0.0003 0.003
Loa Loa (eye worm) hypothetical protein 0.005 0.0032 0.0226
Schistosoma mansoni gliotactin 0.0071 0.0058 0.0058
Loa Loa (eye worm) hypothetical protein 0.005 0.0032 0.0226
Brugia malayi glutathione reductase 0.0047 0.0029 0.0203
Echinococcus multilocularis BC026374 protein (S09 family) 0.0071 0.0058 0.0058
Mycobacterium ulcerans two component regulator - sensor kinase 0.0108 0.0102 0.0305
Loa Loa (eye worm) hypothetical protein 0.0119 0.0114 0.0796
Brugia malayi Cytochrome P450 family protein 0.0027 0.0005 0.0035
Onchocerca volvulus Cathepsin F homolog 0.005 0.0032 0.029
Echinococcus granulosus dna polymerase kappa 0.0023 0.0000098932 0.0000098932
Mycobacterium tuberculosis Probable esterase LipL 0.0149 0.015 0.045
Brugia malayi GRF zinc finger family protein 0.0089 0.0078 0.0547
Echinococcus multilocularis heat shock protein 0.0349 0.039 0.039
Echinococcus multilocularis glycine receptor subunit alpha 1 0.005 0.0032 0.0032
Plasmodium vivax ataxin-2 like protein, putative 0.0052 0.0034 0.0196
Echinococcus multilocularis thyroid hormone receptor alpha 0.0155 0.0158 0.0158
Leishmania major DNA topoisomerase ii 0.0781 0.0908 0.7287
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0179 0.0187 0.0187
Schistosoma mansoni nuclear hormone receptor 0.003 0.0008 0.0008
Mycobacterium ulcerans two component sensor histidine kinase DevS 0.0108 0.0102 0.0305
Brugia malayi hypothetical protein 0.0146 0.0147 0.1024
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.012 0.0116 0.0116
Echinococcus multilocularis acetylcholinesterase 0.0422 0.0477 0.0477
Plasmodium falciparum thioredoxin reductase 0.0047 0.0029 0.0162
Trichomonas vaginalis D-aminoacylase, putative 0.0149 0.015 0.1351
Mycobacterium ulcerans acyl-CoA synthetase 0.0035 0.0015 0.0044
Leishmania major cathepsin L-like protease 0.005 0.0032 0.0258
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0085 0.0074 0.0222
Leishmania major heat shock protein 83-1 0.0349 0.039 0.3131
Toxoplasma gondii heat shock protein HSP90 0.0349 0.039 0.2391
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0191 0.0201 0.1612
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0047 0.0028 0.0028
Echinococcus granulosus acetylcholinesterase 0.0422 0.0477 0.0477
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.003 0.0008 0.0008
Toxoplasma gondii hypothetical protein 0.0055 0.0039 0.019
Loa Loa (eye worm) thioredoxin reductase 0.0047 0.0029 0.0203
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0106 0.0099 0.0296
Onchocerca volvulus 0.0951 0.1111 1
Schistosoma mansoni endoplasmin 0.0349 0.039 0.039
Trichomonas vaginalis antibiotic synthetase, putative 0.0035 0.0015 0.0131
Echinococcus multilocularis zinc finger protein 0.0026 0.0003 0.0003
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0179 0.0187 0.0187
Echinococcus multilocularis endoplasmin 0.0241 0.026 0.026
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0108 0.0102 0.0263
Entamoeba histolytica hypothetical protein 0.0146 0.0147 0.1447
Brugia malayi exodeoxyribonuclease III family protein 0.0055 0.0038 0.0265
Echinococcus granulosus lamin dm0 0.0079 0.0066 0.0066
Brugia malayi kinase, mitochondrial precursor 0.0108 0.0102 0.071
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0106 0.0099 0.0253
Loa Loa (eye worm) PHD-finger family protein 0.003 0.0008 0.0058
Loa Loa (eye worm) hypothetical protein 0.0161 0.0165 0.1151
Trypanosoma brucei transcription factor BTF3, putative 0.0034 0.0013 0.0104
Echinococcus granulosus retinoic acid receptor rxr beta a 0.003 0.0008 0.0008
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0121 0.0117 0.0308
Echinococcus multilocularis cathepsin l cysteine peptidase 0.005 0.0032 0.0032
Echinococcus multilocularis cysteine protease 0.005 0.0032 0.0032
Onchocerca volvulus Cathepsin L homolog 0.005 0.0032 0.029
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.005 0.0032 0.0032
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0062 0.0047 0.0375
Loa Loa (eye worm) hypothetical protein 0.0027 0.0005 0.0033
Entamoeba histolytica cysteine protease, putative 0.0026 0.0003 0.003
Echinococcus granulosus nAChR subunit 0.005 0.0032 0.0032
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.005 0.0032 0.0032
Mycobacterium ulcerans lipase LipD 0.0149 0.015 0.045
Onchocerca volvulus 0.0027 0.0005 0.0042
Brugia malayi Intermediate filament tail domain containing protein 0.0079 0.0066 0.0463
Loa Loa (eye worm) carboxylesterase 0.0071 0.0058 0.0401
Toxoplasma gondii propionate-CoA ligase 0.0035 0.0015 0.004
Entamoeba histolytica hypothetical protein 0.0146 0.0147 0.1447
Trypanosoma brucei Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative 0.0108 0.0102 0.0817
Entamoeba histolytica cysteine proteinase, putative 0.0026 0.0003 0.003
Echinococcus granulosus casein kinase i 0.0039 0.0019 0.0019
Schistosoma mansoni thyroid hormone receptor 0.0155 0.0158 0.0158
Schistosoma mansoni jumonji domain containing protein 0.0252 0.0274 0.0274
Schistosoma mansoni hypothetical protein 0.0125 0.0122 0.0122
Echinococcus granulosus sterol regulatory element binding protein 0.0085 0.0074 0.0074
Leishmania major developmentally regulated phosphoprotein-like protein 0.0108 0.0102 0.0817
Schistosoma mansoni serine/threonine protein kinase 0.0062 0.0047 0.0047
Brugia malayi casein kinase 1, delta 0.0039 0.0019 0.0132
Loa Loa (eye worm) hypothetical protein 0.003 0.0008 0.0058
Loa Loa (eye worm) DNA topoisomerase III 0.0089 0.0078 0.0547
Echinococcus granulosus beta LACTamase domain containing family member 0.0149 0.015 0.015
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0284 0.0312 0.2806
Loa Loa (eye worm) intermediate filament protein 0.0079 0.0066 0.0463
Brugia malayi Cathepsin L-like cysteine proteinase 0.0034 0.0012 0.0086
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.005 0.0032 0.0226
Loa Loa (eye worm) hypothetical protein 0.0034 0.0012 0.0086
Wolbachia endosymbiont of Brugia malayi DNA gyrase, topoisomerase II, B subunit, GyrB 0.0988 0.1155 0.7133
Trichomonas vaginalis heat shock protein, putative 0.0241 0.026 0.2344
Leishmania major heat shock protein 83-1 0.0349 0.039 0.3131
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.005 0.0032 0.0226
Mycobacterium tuberculosis Carboxylesterase LipT 0.0071 0.0058 0.0172
Brugia malayi RNA binding protein 0.0062 0.0046 0.0322
Entamoeba histolytica cysteine protease, putative 0.0026 0.0003 0.003
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0047 0.0028 0.0028
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0108 0.0102 0.0305
Trypanosoma cruzi developmentally regulated phosphoprotein, putative 0.0108 0.0102 0.0817
Brugia malayi Nuclear hormone receptor family member nhr-31 0.003 0.0008 0.0058
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.005 0.0032 0.0289
Leishmania major hypothetical protein, conserved 0.0108 0.0102 0.0817
Brugia malayi Carboxylesterase family protein 0.0071 0.0058 0.0401
Brugia malayi AMP-binding enzyme family protein 0.0035 0.0015 0.0102
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0052 0.0035 0.0242
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.005 0.0032 0.0226
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0035 0.0015 0.0044
Schistosoma mansoni phd/f-box containing protein 0.0056 0.0039 0.0039
Onchocerca volvulus 0.0149 0.015 0.1352
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0071 0.0058 0.0058
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0065 0.005 0.005
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0179 0.0187 0.1497
Echinococcus granulosus dual specificity 0.0092 0.0082 0.0082
Entamoeba histolytica heat shock protein 90, putative 0.0349 0.039 0.3846
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0161 0.0165 0.0982
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0055 0.0038 0.0304
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0161 0.0165 0.0567
Trypanosoma brucei heat shock protein, putative 0.0349 0.039 0.3131
Plasmodium vivax JmjC domain containing protein 0.0056 0.0039 0.0225
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0118 0.0114 0.0114
Mycobacterium ulcerans acyl-CoA synthetase 0.0035 0.0015 0.0044
Schistosoma mansoni hypothetical protein 0.003 0.0008 0.0008
Trichomonas vaginalis DNA topoisomerase II, putative 0.087 0.1014 0.9128
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0284 0.0312 0.3074
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0191 0.0201 0.1612
Echinococcus granulosus lamin 0.0079 0.0066 0.0066
Loa Loa (eye worm) CYP4Cod1 0.0027 0.0005 0.0035
Schistosoma mansoni endoplasmin 0.0349 0.039 0.039
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.005 0.0032 0.0289
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.003 0.0008 0.0008
Echinococcus multilocularis dna polymerase kappa 0.0023 0.0000098932 0.0000098932
Entamoeba histolytica heat shock protein 90, putative 0.0349 0.039 0.3846
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.003 0.0008 0.0058
Echinococcus multilocularis thioredoxin glutathione reductase 0.0047 0.0029 0.0029
Loa Loa (eye worm) hypothetical protein 0.005 0.0032 0.0226
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.009 0.0079 0.0079
Brugia malayi Probable DNA topoisomerase II 0.087 0.1014 0.7071
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0056 0.0039 0.0194
Entamoeba histolytica cysteine proteinase 1, putative 0.0026 0.0003 0.003
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0136 0.0135 0.0135
Mycobacterium leprae Probable DNA gyrase (subunit A) GyrA (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (Type II DNA topoisomerase) 0.0419 0.0473 0.1383
Trichomonas vaginalis mismatch repair protein Mlh1C (mutL homolog) 0.0108 0.0102 0.0916
Loa Loa (eye worm) hypothetical protein 0.0069 0.0054 0.0379
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.005 0.0032 0.0032
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0035 0.0015 0.0044
Brugia malayi photoreceptor-specific nuclear receptor 0.003 0.0008 0.0058
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0148 0.0149 0.1041
Schistosoma mansoni acetylcholinesterase 0.0071 0.0058 0.0058
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0038 0.0018 0.0018
Leishmania major heat shock protein 83-1 0.0349 0.039 0.3131
Loa Loa (eye worm) hypothetical protein 0.0023 0.0000098932 0.0001
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0092 0.0082 0.0656
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0136 0.0135 0.0135
Mycobacterium ulcerans aldehyde dehydrogenase 0.0179 0.0187 0.0559
Brugia malayi Niemann-Pick C1 protein precursor 0.0199 0.021 0.1467
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0179 0.0187 0.0559
Leishmania major heat shock protein 83-1 0.0349 0.039 0.3131
Loa Loa (eye worm) hypothetical protein 0.0056 0.0039 0.0273
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.005 0.0032 0.0226
Leishmania major 4-coumarate:coa ligase-like protein 0.0121 0.0117 0.0936
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0039 0.0019 0.0132
Echinococcus multilocularis peptidase Clp (S14 family) 0.0106 0.0099 0.0099
Echinococcus granulosus histone acetyltransferase KAT2B 0.0279 0.0306 0.0306
Onchocerca volvulus Protein ultraspiracle homolog 0.003 0.0008 0.0075
Trichomonas vaginalis CK1 family protein kinase 0.0039 0.0019 0.017
Mycobacterium tuberculosis Two component sensor histidine kinase DosT 0.0108 0.0102 0.0305
Loa Loa (eye worm) hypothetical protein 0.0479 0.0545 0.3802
Echinococcus multilocularis heat shock protein 90 0.0349 0.039 0.039
Echinococcus multilocularis ubiquitin specific protease 41 0.0038 0.0017 0.0017
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0055 0.0039 0.0222
Echinococcus multilocularis lamin 0.0079 0.0066 0.0066
Trypanosoma cruzi cysteine peptidase, putative 0.0191 0.0201 0.1612
Loa Loa (eye worm) hypothetical protein 0.005 0.0032 0.0226
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0035 0.0015 0.0044
Mycobacterium tuberculosis Possible two component sensor kinase 0.0108 0.0102 0.0305
Trypanosoma brucei DNA topoisomerase IA, putative 0.0089 0.0078 0.0629
Echinococcus granulosus cathepsin L 0.0026 0.0003 0.0003
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.005 0.0032 0.0289
Mycobacterium leprae Probable DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (Type II DNA topoisomerase) 0.0271 0.0296 0.0849
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.009 0.0079 0.0079
Mycobacterium ulcerans sensor kinase from two component regulatory system 0.0108 0.0102 0.0305
Schistosoma mansoni nAChR subunit 0.005 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0121 0.0117 0.0813
Schistosoma mansoni steroid hormone receptor ad4bp 0.003 0.0008 0.0008
Leishmania major trypanothione reductase 0.0047 0.0029 0.0232
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0146 0.0147 0.0147
Onchocerca volvulus 0.0071 0.0058 0.0518
Plasmodium falciparum glutathione reductase 0.0047 0.0029 0.0162
Schistosoma mansoni terminal deoxycytidyl transferase 0.0023 0.0000098932 0.0000098932
Mycobacterium ulcerans acyl-CoA synthetase 0.0035 0.0015 0.0044
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.012 0.0116 0.0349
Loa Loa (eye worm) hypothetical protein 0.0027 0.0005 0.0033
Echinococcus multilocularis casein kinase i 0.0039 0.0019 0.0019
Plasmodium vivax acyl-CoA synthetase, putative 0.009 0.008 0.0481
Trichomonas vaginalis sensor histidine kinase, putative 0.0108 0.0102 0.0916
Echinococcus multilocularis heat shock protein 90 0.0241 0.026 0.026
Leishmania major heat shock protein 83-1 0.0349 0.039 0.3131
Chlamydia trachomatis DNA gyrase subunit A 0.0262 0.0285 0.1357
Treponema pallidum DNA topoisomerase I (topA) 0.0089 0.0078 0.0258
Plasmodium falciparum cysteine proteinase falcipain 2b 0.005 0.0032 0.0182
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0046 0.0046
Schistosoma mansoni inositol monophosphatase 0.0074 0.0061 0.0061
Schistosoma mansoni protein kinase 0.0039 0.0019 0.0019
Entamoeba histolytica cysteine protease, putative 0.005 0.0032 0.0317
Echinococcus granulosus DNA topoisomerase 3 beta 1 0.0089 0.0078 0.0078
Leishmania major cathepsin L-like protease 0.0191 0.0201 0.1612
Trichomonas vaginalis prokaryotic DNA topoisomerase, putative 0.0089 0.0078 0.0705
Trichomonas vaginalis ap endonuclease, putative 0.0055 0.0038 0.0341
Mycobacterium ulcerans transcriptional regulator 0.2807 0.3332 1
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0047 0.0028 0.0028
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.003 0.0008 0.0008
Giardia lamblia DNA topoisomerase III 0.0089 0.0078 0.0886
Schistosoma mansoni hypothetical protein 0.0146 0.0147 0.0147
Onchocerca volvulus 0.005 0.0032 0.029
Schistosoma mansoni hypothetical protein 0.0047 0.0028 0.0028
Brugia malayi Nuclear hormone receptor-like 1 0.003 0.0008 0.0058
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.005 0.0032 0.0226
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0035 0.0015 0.0102
Trypanosoma brucei cytochrome P450, putative 0.0027 0.0005 0.004
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.009 0.0079 0.0079
Trichomonas vaginalis penicillin-binding protein, putative 0.0149 0.015 0.1351
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0085 0.0074 0.0222
Entamoeba histolytica protein kinase domain containing protein 0.0092 0.0082 0.0806
Echinococcus multilocularis jumonji domain containing protein 0.0042 0.0022 0.0022
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0284 0.0312 0.2806
Trichomonas vaginalis CMGC family protein kinase 0.0062 0.0047 0.0421
Schistosoma mansoni nAChR subunit 0.005 0.0032 0.0032
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0731 0.0847 0.7624
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0035 0.0015 0.0117
Leishmania major heat shock protein 83-1 0.0349 0.039 0.3131
Entamoeba histolytica protein kinase, putative 0.0092 0.0082 0.0806
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.005 0.0032 0.0226
Echinococcus multilocularis beta LACTamase domain containing family member 0.0149 0.015 0.015
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0121 0.0117 0.0308
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0055 0.0038 0.0373
Brugia malayi AMP-binding enzyme family protein 0.0035 0.0015 0.0102
Echinococcus granulosus endoplasmin 0.0241 0.026 0.026
Trypanosoma brucei DNA topoisomerase II beta, putative 0.0781 0.0908 0.7287
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.005 0.0032 0.0225
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0074 0.0061 0.0331
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0046 0.0046
Trypanosoma cruzi casein kinase, putative 0.0039 0.0019 0.0152
Onchocerca volvulus Putative DNA topoisomerase 2, mitochondrial 0.0731 0.0847 0.7624
Schistosoma mansoni nAChR subunit 0.005 0.0032 0.0032
Mycobacterium ulcerans DNA gyrase subunit B 0.0988 0.1155 0.3467
Brugia malayi jmjC domain containing protein 0.0212 0.0226 0.1574
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.332 0.3947 0.3947
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0191 0.0201 0.1612
Trichomonas vaginalis CK1 family protein kinase 0.0039 0.0019 0.017
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0035 0.0015 0.0044
Mycobacterium ulcerans esterase/lipase LipP 0.0149 0.015 0.045
Loa Loa (eye worm) TOPoisomerase family member 0.087 0.1014 0.7071
Brugia malayi beta-lactamase family protein 0.0149 0.015 0.1047
Trypanosoma brucei RNA helicase, putative 0.0109 0.0102 0.0821
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0074 0.0061 0.049
Schistosoma mansoni heat shock protein 0.0124 0.0121 0.0121
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0191 0.0201 0.1612
Brugia malayi Calcitonin receptor-like protein seb-1 0.0148 0.0149 0.1041
Leishmania major hypothetical protein, conserved 0.0052 0.0034 0.0276
Echinococcus multilocularis PHD finger protein rhinoceros 0.003 0.0008 0.0008
Mycobacterium tuberculosis Two component sensor kinase [second part] 0.0108 0.0102 0.0305
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.005 0.0032 0.0226
Brugia malayi ecdysteroid receptor 0.003 0.0008 0.0058
Onchocerca volvulus 0.005 0.0032 0.029
Wolbachia endosymbiont of Brugia malayi signal transduction histidine kinase and receiver 0.0108 0.0102 0.0407
Toxoplasma gondii DNA topoisomerase family protein 0.0089 0.0078 0.0439
Mycobacterium tuberculosis Conserved protein 0.0108 0.0102 0.0305
Plasmodium falciparum ataxin-2 like protein, putative 0.0052 0.0034 0.0196
Echinococcus multilocularis cathepsin L 0.0026 0.0003 0.0003
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0035 0.0015 0.0044
Mycobacterium ulcerans acyl-CoA synthetase 0.0035 0.0015 0.0044
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0108 0.0102 0.0102
Plasmodium falciparum DNA topoisomerase VI, b subunit, putative 0.0108 0.0102 0.0616
Echinococcus granulosus casein kinase I alpha 0.0039 0.0019 0.0019
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0035 0.0015 0.0117
Mycobacterium tuberculosis Probable dehydrogenase 0.0108 0.0102 0.0305
Onchocerca volvulus 0.0121 0.0117 0.105
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.003 0.0008 0.0008
Plasmodium falciparum DNA gyrase subunit A 0.1364 0.1605 1
Trypanosoma cruzi Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative 0.0108 0.0102 0.0817
Schistosoma mansoni hypothetical protein 0.0502 0.0573 0.0573
Echinococcus granulosus FTZ F1 alpha 0.003 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0077 0.0065 0.0452
Echinococcus granulosus JmjC domain containing protein 4 0.0056 0.0039 0.0039

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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