Detailed information for compound 590006

Basic information

Technical information
  • TDR Targets ID: 590006
  • Name: [[5-[2,4-dioxo-5-[(E)-3-[3-[2-[5-(2-oxo-1,3,3 a,4,6,6a-hexahydrothieno[3,4-d]imidazol-6-yl) pentanoylamino]ethyldisulfanyl]propanoylamino ]prop-1-enyl]pyrimidin-1-yl]-3-hydroxy-tetrah ydrofuran-2-yl]methoxy-hydroxy-phosphoryl] ph osphono hydrogen phosphate
  • MW: 912.777 | Formula: C27H43N6O17P3S3
  • H donors: 10 H acceptors: 13 LogP: -4.92 Rotable bonds: 25
    Rule of 5 violations (Lipinski): 4
  • SMILES: O=C(NC/C=C/c1cn(C2CC(C(O2)COP(=O)(OP(=O)(OP(=O)(O)O)O)O)O)c(=O)[nH]c1=O)CCSSCCNC(=O)CCCCC1SCC2C1NC(=O)N2
  • InChi: 1S/C27H43N6O17P3S3/c34-18-12-23(48-19(18)14-47-52(43,44)50-53(45,46)49-51(40,41)42)33-13-16(25(37)32-27(33)39)4-3-8-28-22(36)7-10-55-56-11-9-29-21(35)6-2-1-5-20-24-17(15-54-20)30-26(38)31-24/h3-4,13,17-20,23-24,34H,1-2,5-12,14-15H2,(H,28,36)(H,29,35)(H,43,44)(H,45,46)(H2,30,31,38)(H,32,37,39)(H2,40,41,42)/b4-3+
  • InChiKey: OWJRLHWTPUNEQA-ONEGZZNKSA-N  


Substructure search Similarity search

Network

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Synonyms

  • [[5-[2,4-dioxo-5-[(E)-3-[[1-oxo-3-[2-[[1-oxo-5-(2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-6-yl)pentyl]amino]ethyldisulfanyl]propyl]amino]prop-1-enyl]-1-pyrimidinyl]-3-hydroxy-2-tetrahydrofuranyl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate
  • [[5-[2,4-dioxo-5-[(E)-3-[3-[2-[5-(2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-6-yl)pentanoylamino]ethyldisulfanyl]propanoylamino]prop-1-enyl]pyrimidin-1-yl]-3-hydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl] phosphono hydrogen phosphate
  • [[5-[2,4-diketo-5-[(E)-3-[3-[2-[5-(2-keto-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-6-yl)pentanoylamino]ethyldisulfanyl]propanoylamino]prop-1-enyl]pyrimidin-1-yl]-3-hydroxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl] phosphono hydrogen phosphate
  • [[5-[2,4-dioxo-5-[(E)-3-[3-[2-[5-(2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-6-yl)pentanoylamino]ethyldisulfanyl]propanoylamino]prop-1-enyl]pyrimidin-1-yl]-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate
  • biotin-12-SS-dUTP
  • [5-[2,4-dioxo-5-[(E)-3-[3-[2-[5-(2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-6-yl)pentanoylamino]ethyldisulfanyl]propanoylamino]prop-1-enyl]pyrimidin-1-yl]-3-hydroxyoxolan-2-yl]methyl (hydroxy-phosphonooxyphosphoryl) hydrogen phosphate
  • [5-[2,4-dioxo-5-[(E)-3-[3-[2-[5-(2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-6-yl)pentanoylamino]ethyldisulfanyl]propanoylamino]prop-1-enyl]pyrimidin-1-yl]-3-hydroxy-tetrahydrofuran-2-yl]methyl (hydroxy-phosphonooxy-phosphoryl) hydrogen phosphate
  • [5-[2,4-dioxo-5-[(E)-3-[[1-oxo-3-[2-[[1-oxo-5-(2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-6-yl)pentyl]amino]ethyldisulfanyl]propyl]amino]prop-1-enyl]-1-pyrimidinyl]-3-hydroxy-2-tetrahydrofuranyl]methyl (hydroxy-phosphonooxyphosphoryl) hydrogen phosphate
  • [5-[2,4-diketo-5-[(E)-3-[3-[2-[5-(2-keto-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-6-yl)pentanoylamino]ethyldisulfanyl]propanoylamino]prop-1-enyl]pyrimidin-1-yl]-3-hydroxy-tetrahydrofuran-2-yl]methyl (hydroxy-phosphonooxy-phosphoryl) hydrogen phosphate
  • [5-[2,4-dioxo-5-[(E)-3-[3-[2-[5-(2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-6-yl)pentanoylamino]ethyldisulfanyl]propanoylamino]prop-1-enyl]pyrimidin-1-yl]-3-hydroxy-oxolan-2-yl]methyl (hydroxy-phosphonooxy-phosphoryl) hydrogen phosphate
  • 97068-12-7
  • Bio-12-SS-dutp
  • Uridine 5'-(tetrahydrogen triphosphate), 2'-deoxy-5-(3-((3-((2-((5-(hexahydro-2-oxo-1H-thieno(3,4-d)imidazol-4-yl)-1-oxopentyl)amino)ethyl)dithio)-1-oxopropyl)amino)-1-propenyl)-, (3aR-(3aalpha,4beta,6aalpha))-

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0154 0.096 0.1357
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0353 0.304 0.4901
Onchocerca volvulus 0.0076 0.0149 0.0213
Brugia malayi hypothetical protein 0.0222 0.1677 0.1822
Brugia malayi Fes/CIP4 homology domain containing protein 0.0117 0.0571 0.0621
Echinococcus multilocularis serine:threonine protein kinase 0.0114 0.0546 0.0635
Trypanosoma cruzi casein kinase, putative 0.0109 0.0489 0.0578
Echinococcus granulosus cGMP dependent protein kinase 1 0.0135 0.076 0.0707
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0135 0.076 0.0896
Schistosoma mansoni serine/threonine protein kinase 0.0325 0.2753 0.4446
Echinococcus multilocularis serine:threonine protein kinase N2 0.013 0.0704 0.0827
Plasmodium falciparum serine/threonine protein kinase 0.0083 0.0222 0.0394
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0083 0.022 0.0347
Schistosoma mansoni tyrosine kinase 0.0449 0.405 0.6547
Trichomonas vaginalis CAMK family protein kinase 0.0114 0.0546 0.0876
Echinococcus granulosus dual specificity protein kinase clk2 0.0154 0.096 0.0907
Echinococcus multilocularis dual specificity 0.0139 0.0806 0.0952
Brugia malayi RhoGAP domain containing protein 0.0099 0.0384 0.0418
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0233 0.1791 0.2153
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0216 0.1612 0.1935
Echinococcus granulosus serine:threonine protein kinase mig 15 0.0232 0.1773 0.1725
Brugia malayi Protein kinase domain containing protein 0.0082 0.0205 0.0223
Onchocerca volvulus Serine\/threonine kinase homolog 0.0653 0.6184 1
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0082 0.0205 0.0204
Entamoeba histolytica casein kinase 1, putative 0.0109 0.0489 0.0753
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0159 0.1017 0.1377
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0101 0.0408 0.1214
Schistosoma mansoni tyrosine kinase 0.026 0.2075 0.3349
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0109 0.0489 0.0514
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0119 0.0595 0.2272
Brugia malayi Protein kinase domain containing protein 0.0119 0.0595 0.0647
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0245 0.1915 0.2305
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0101 0.0408 0.0352
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0098 0.0377 0.0391
Schistosoma mansoni tyrosine kinase 0.0404 0.3574 0.5775
Schistosoma mansoni tyrosine kinase 0.0373 0.3251 0.5253
Giardia lamblia Kinase, STE STE20 0.0086 0.0252 0.0051
Loa Loa (eye worm) casein kinase 0.018 0.1233 0.1324
Loa Loa (eye worm) TK protein kinase 0.035 0.3015 0.3263
Schistosoma mansoni protein kinase 0.0265 0.2123 0.3426
Echinococcus multilocularis mitogen activated protein kinase 11 0.0159 0.1017 0.1209
Echinococcus multilocularis homeodomain interacting protein kinase 3 0.0203 0.1472 0.1764
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0146 0.0874 0.1378
Entamoeba histolytica cell division protein kinase 2, putative 0.0119 0.0595 0.0925
Echinococcus granulosus protein kinase shaggy 0.0129 0.0699 0.0644
Trichomonas vaginalis CAMK family protein kinase 0.0653 0.6184 1
Trypanosoma cruzi cdc2-related kinase 1 0.0119 0.0595 0.0754
Schistosoma mansoni protein kinase 0.0434 0.389 0.6287
Schistosoma mansoni serine/threonine protein kinase 0.0089 0.028 0.0443
Giardia lamblia Kinase, AGC AKT 0.0117 0.0577 0.0596
Echinococcus granulosus raf serine:threonine protein kinase 0.0089 0.028 0.0223
Giardia lamblia Kinase, PLK 0.0653 0.6184 1
Entamoeba histolytica PH domain containing protein kinase, putative 0.0122 0.0628 0.0979
Brugia malayi Protein kinase domain containing protein 0.0201 0.1452 0.1578
Schistosoma mansoni rap gtpase-activating protein 0.0112 0.0517 0.0827
Brugia malayi Casein kinase II, alpha chain 0.01 0.04 0.0435
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0216 0.1612 0.1563
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0119 0.0595 0.0629
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0101 0.0408 0.1214
Entamoeba histolytica protein kinase, putative 0.0071 0.0094 0.0111
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0113 0.0535 0.0573
Schistosoma mansoni serine/threonine protein kinase 0.0237 0.1828 0.2949
Entamoeba histolytica PH domain containing protein kinase, putative 0.0122 0.0628 0.0979
Echinococcus multilocularis ephrin type A receptor 4 A 0.0111 0.0512 0.0593
Trypanosoma brucei rac serine-threonine kinase, putative 0.0259 0.2062 0.3121
Brugia malayi Fibronectin type III domain containing protein 0.0099 0.0384 0.0417
Schistosoma mansoni protein kinase 0.0434 0.389 0.6287
Echinococcus multilocularis activin receptor type 0.0081 0.0192 0.0203
Entamoeba histolytica protein kinase domain containing protein 0.0139 0.0806 0.1268
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0123 0.0631 0.0813
Plasmodium falciparum NIMA related kinase 1 0.0136 0.0777 0.7617
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0653 0.6184 0.6162
Brugia malayi Protein kinase domain containing protein 0.0175 0.1176 0.1278
Loa Loa (eye worm) TK/ROR protein kinase 0.0069 0.0069 0.0056
Loa Loa (eye worm) TK/FAK protein kinase 0.0559 0.5197 0.564
Echinococcus granulosus rho-associated protein kinase 1 0.0325 0.2753 0.271
Trypanosoma brucei protein kinase, putative 0.0129 0.0699 0.0846
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.0232 0.178 0.1919
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0465 0.4214 0.418
Entamoeba histolytica PH domain containing protein kinase, putative 0.0138 0.0797 0.1252
Schistosoma mansoni serine/threonine protein kinase 0.0238 0.1842 0.2972
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0353 0.304 0.3303
Schistosoma mansoni protein kinase 0.0434 0.389 0.6287
Schistosoma mansoni protein kinase 0.0193 0.1369 0.2207
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0367 0.3188 0.3148
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0288 0.0458
Echinococcus granulosus serine:threonine protein kinase 3 0.0257 0.2039 0.1992
Brugia malayi Sex muscle abnormal protein 5 0.0098 0.0377 0.0409
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0123 0.0631 0.0733
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0086 0.0252 0.0196
Echinococcus granulosus Immunoglobulin 0.0083 0.022 0.0163
Echinococcus multilocularis tyrosine protein kinase Abl 0.0225 0.17 0.2042
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0084 0.0229 0.023
Loa Loa (eye worm) TK/ALK protein kinase 0.0283 0.2315 0.2502
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0434 0.389 0.3855
Trypanosoma brucei aurora B kinase 0.0146 0.0874 0.1139
Loa Loa (eye worm) hypothetical protein 0.0123 0.0639 0.0676
Trichomonas vaginalis CMGC family protein kinase 0.01 0.04 0.0639
Trypanosoma cruzi polo-like protein kinase, putative 0.0653 0.6184 1
Schistosoma mansoni ste20-related kinase 0.0205 0.1498 0.2415
Brugia malayi Protein kinase domain containing protein 0.0104 0.0441 0.0479
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0099 0.0384 0.0399
Echinococcus granulosus mitogen activated protein kinase 14 0.0159 0.1017 0.0965
Trichomonas vaginalis CK1 family protein kinase 0.0109 0.0489 0.0784
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0154 0.096 0.4322
Schistosoma mansoni serine/threonine kinase 0.0217 0.1622 0.2616
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0404 0.3574 0.3536
Echinococcus granulosus serine:threonine kinase SAD 1 0.009 0.0288 0.0231
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.0394 0.3475 0.3764
Entamoeba histolytica casein kinase, putative 0.01 0.04 0.0608
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0112 0.0517 0.0827
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0123 0.0631 0.0813
Schistosoma mansoni tyrosine kinase 0.0087 0.0261 0.0412
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0101 0.0408 0.4247
Brugia malayi probable protein kinase 0.0265 0.2123 0.2307
Loa Loa (eye worm) TK/FER protein kinase 0.0104 0.0441 0.0461
Loa Loa (eye worm) hypothetical protein 0.0143 0.0849 0.0906
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0135 0.076 0.3201
Schistosoma mansoni hypothetical protein 0.0102 0.0414 0.066
Entamoeba histolytica p21-activated kinase 0.0095 0.0346 0.052
Trichomonas vaginalis CMGC family protein kinase 0.01 0.04 0.0639
Loa Loa (eye worm) hypothetical protein 0.0461 0.4173 0.4524
Echinococcus granulosus hypothetical protein 0.0121 0.061 0.0555
Brugia malayi Protein kinase domain containing protein 0.0367 0.3188 0.3464
Schistosoma mansoni serine/threonine protein kinase 0.0222 0.1677 0.2704
Trypanosoma cruzi polo-like protein kinase, putative 0.0653 0.6184 1
Echinococcus multilocularis casein kinase I alpha 0.0109 0.0489 0.0565
Schistosoma mansoni tyrosine kinase 0.0356 0.3079 0.4975
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0084 0.0229 0.0061
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0145 0.0871 0.14
Plasmodium falciparum protein kinase 5 0.0119 0.0595 0.5256
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0119 0.0595 0.0629
Brugia malayi Protein kinase domain containing protein 0.0448 0.4043 0.4394
Echinococcus granulosus twitchin 0.0138 0.0797 0.0743
Schistosoma mansoni protein kinase 0.0367 0.3188 0.5151
Brugia malayi SRC-1 0.0233 0.1791 0.1946
Plasmodium vivax serine/threonine protein kinase, putative 0.0083 0.0222 0.2314
Echinococcus multilocularis serine:threonine protein kinase N2 0.0154 0.0963 0.1143
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0129 0.0699 0.0741
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0084 0.0229 0.0061
Schistosoma mansoni serine/threonine protein kinase 0.0139 0.0806 0.1295
Loa Loa (eye worm) hypothetical protein 0.0113 0.0535 0.0563
Loa Loa (eye worm) SRC-1 0.0233 0.1791 0.193
Trichomonas vaginalis AGC family protein kinase 0.0259 0.2062 0.3329
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0083 0.022 0.0238
Echinococcus granulosus mitogen activated protein kinase 3 0.0084 0.0229 0.0172
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0123 0.0631 0.0733
Loa Loa (eye worm) AGC/PKG protein kinase 0.0135 0.076 0.0809
Giardia lamblia Kinase, CAMK CAMKL 0.009 0.0288 0.011
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0091 0.0297 0.044
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0245 0.1915 0.1868
Loa Loa (eye worm) hypothetical protein 0.0099 0.0384 0.0399
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0129 0.0703 0.0649
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0145 0.0866 0.0813
Trichomonas vaginalis AGC family protein kinase 0.0184 0.127 0.2047
Trichomonas vaginalis CMGC family protein kinase 0.0139 0.0806 0.1297
Loa Loa (eye worm) hypothetical protein 0.0114 0.0546 0.0576
Loa Loa (eye worm) hypothetical protein 0.018 0.1237 0.1327
Trichomonas vaginalis AGC family protein kinase 0.0259 0.2062 0.3329
Echinococcus multilocularis protein kinase c iota type 0.0279 0.2267 0.2734
Plasmodium falciparum casein kinase 2, alpha subunit 0.01 0.04 0.271
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0236 0.1818 0.177
Trypanosoma cruzi casein kinase, putative 0.0109 0.0489 0.0578
Loa Loa (eye worm) hypothetical protein 0.0086 0.0246 0.0248
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0129 0.0699 0.0644
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0288 0.0458
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0288 0.0458
Schistosoma mansoni serine/threonine protein kinase 0.009 0.0288 0.0456
Echinococcus multilocularis c src tyrosine kinase 0.0145 0.0871 0.1031
Brugia malayi Temporarily assigned gene name protein 59 0.0112 0.0517 0.0561
Loa Loa (eye worm) hypothetical protein 0.0089 0.0282 0.0288
Echinococcus granulosus ephrin type A receptor 4 A 0.0111 0.0512 0.0456
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0113 0.0535 0.0621
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.0394 0.3475 0.4207
Schistosoma mansoni serine/threonine protein kinase 0.0113 0.0535 0.0856
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0367 0.3188 0.3857
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0085 0.0238 0.0163
Trichomonas vaginalis CMGC family protein kinase 0.009 0.0292 0.0464
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0407 0.3613 0.3576
Echinococcus granulosus serine:threonine protein kinase N2 0.013 0.0704 0.065
Brugia malayi MAP kinase sur-1 0.0084 0.0229 0.0248
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.008 0.0185 0.0128
Entamoeba histolytica serine/threonine protein kinase, putative 0.009 0.0288 0.0426
Giardia lamblia Kinase, CMGC MAPK 0.0084 0.0229 0.0011
Brugia malayi hypothetical protein 0.0104 0.0441 0.0479
Loa Loa (eye worm) AGC/PKA protein kinase 0.0113 0.0535 0.0563
Echinococcus granulosus insulin receptor 0.0449 0.405 0.4016
Echinococcus granulosus dual specificity 0.0123 0.0631 0.0577
Trichomonas vaginalis AGC family protein kinase 0.0175 0.1176 0.1896
Loa Loa (eye worm) hypothetical protein 0.0119 0.0592 0.0625
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0236 0.1818 0.2186
Entamoeba histolytica protein kinase domain containing protein 0.0123 0.0631 0.0983
Schistosoma mansoni serine/threonine protein kinase 0.0084 0.0229 0.036
Loa Loa (eye worm) hypothetical protein 0.0101 0.0408 0.0425
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0312 0.261 0.3152
Echinococcus granulosus tyrosine protein kinase Srms 0.0512 0.4704 0.4673
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0139 0.0806 0.1103
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0233 0.1791 0.2153
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0113 0.0535 0.0573
Brugia malayi Egg laying defective protein 4 0.0135 0.076 0.0826
Brugia malayi ephrin receptor 1 precursor 0.0077 0.0158 0.0171
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0101 0.0408 0.4247
Schistosoma mansoni tyrosine kinase 0.0245 0.1915 0.3091
Onchocerca volvulus 0.0071 0.0088 0.0115
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0129 0.0699 0.1121
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0154 0.096 0.1357
Plasmodium falciparum serine/threonine protein kinase KIN 0.009 0.0288 0.1252
Trichomonas vaginalis AGC family protein kinase 0.0146 0.0874 0.1407
Schistosoma mansoni tyrosine kinase 0.0079 0.017 0.0266
Brugia malayi Cam kinase protein 1 0.0101 0.0408 0.0443
Brugia malayi SH2 domain containing protein 0.0104 0.0441 0.0479
Plasmodium vivax tyrosine kinase-like protein, putative 0.0081 0.02 0.2086
Echinococcus multilocularis tyrosine kinase 0.0104 0.0441 0.0507
Schistosoma mansoni serine/threonine protein kinase 0.0394 0.3475 0.5615
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0186 0.1296 0.1408
Brugia malayi serine/threonine-protein kinase PAK 7 0.0232 0.178 0.1934
Schistosoma mansoni growth factor receptor-bound protein 0.01 0.0398 0.0634
Schistosoma mansoni serine/threonine protein kinase 0.0353 0.304 0.491
Brugia malayi Immunoglobulin I-set domain containing protein 0.0071 0.0088 0.0096
Echinococcus granulosus tyrosine protein kinase Src42A 0.0233 0.1791 0.1743
Echinococcus multilocularis insulin receptor 0.0449 0.405 0.4909
Leishmania major protein kinase A catalytic subunit isoform 1 0.0113 0.0535 0.0573
Schistosoma mansoni tyrosine kinase 0.0553 0.5134 0.8301
Echinococcus granulosus cyclin dependent kinase 0.0119 0.0595 0.0541
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0067 0.0054 0.0039
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.0201 0.1452 0.174
Trichomonas vaginalis CK1 family protein kinase 0.0109 0.0489 0.0784
Schistosoma mansoni protein kinase 0.0081 0.0192 0.0301
Trichomonas vaginalis CMGC family protein kinase 0.0119 0.0595 0.0955
Echinococcus multilocularis mitogen activated protein kinase 11 0.0159 0.1017 0.1209
Brugia malayi Protein kinase domain containing protein 0.06 0.5627 0.6115
Trichomonas vaginalis STE family protein kinase 0.0086 0.0252 0.04
Schistosoma mansoni protein kinase 0.0236 0.1818 0.2932
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0074 0.0126 0.0118
Echinococcus multilocularis expressed conserved protein 0.0135 0.076 0.0896
Schistosoma mansoni protein kinase C mu 0.0218 0.1629 0.2626
Giardia lamblia Aurora kinase 0.0146 0.0874 0.1094
Brugia malayi Variant SH3 domain containing protein 0.0099 0.0384 0.0418
Echinococcus granulosus titin 0.0071 0.0088 0.0031
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0288 0.0458
Echinococcus multilocularis serine:threonine protein kinase 0.0114 0.0546 0.0635
Onchocerca volvulus Serine\/threonine kinase homolog 0.0164 0.1069 0.1705
Loa Loa (eye worm) TK protein kinase 0.0287 0.2349 0.2539
Trichomonas vaginalis CMGC family protein kinase 0.0139 0.0806 0.1297
Schistosoma mansoni serine/threonine protein kinase 0.0213 0.1583 0.2552
Brugia malayi map kinase activated protein kinase protein 2 0.0394 0.3475 0.3776
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.0333 0.2831 0.3063
Brugia malayi serine/threonine protein kinase 6 0.0146 0.0874 0.095
Loa Loa (eye worm) CMGC/DYRK/HIPK protein kinase 0.0203 0.1472 0.1583
Trichomonas vaginalis CMGC family protein kinase 0.0084 0.0229 0.0362
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0082 0.0205 0.0148
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0112 0.0517 0.0624
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0233 0.1791 0.2153
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0084 0.0229 0.0207
Echinococcus multilocularis cyclin dependent kinase 1 0.0119 0.0595 0.0695
Giardia lamblia Kinase, CDC7 0.009 0.0292 0.0117
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0126 0.0671 0.0799
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0264 0.2116 0.255
Echinococcus granulosus casein kinase I delta 0.0109 0.0489 0.0434
Echinococcus granulosus STE20 serine:threonine protein kinase 0.0494 0.4522 0.449
Trichomonas vaginalis CMGC family protein kinase 0.0154 0.096 0.1545
Echinococcus multilocularis tyrosine protein kinase shark 0.0318 0.2674 0.323
Echinococcus multilocularis Glutaredoxin protein 5 0.0096 0.0354 0.04
Echinococcus multilocularis mitogen activated protein kinase 14 0.0159 0.1017 0.1209
Loa Loa (eye worm) AUR protein kinase 0.0146 0.0874 0.0933
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0233 0.1791 0.2153
Echinococcus multilocularis dual specificity 0.0139 0.0806 0.0952
Schistosoma mansoni tyrosine kinase 0.0404 0.3574 0.5775
Echinococcus multilocularis neuroglian 0.0105 0.0447 0.0514
Loa Loa (eye worm) hypothetical protein 0.0139 0.0799 0.0851
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0233 0.1791 0.2153
Entamoeba histolytica protein kinase, putative 0.0129 0.0699 0.1093
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0186 0.1296 0.1245
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0119 0.0595 0.0541
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0288 0.0458
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0159 0.1017 0.1451
Toxoplasma gondii casein kinase I 0.0109 0.0489 0.1674
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0154 0.096 0.1357
Loa Loa (eye worm) hypothetical protein 0.0081 0.02 0.0199
Schistosoma mansoni nephrin 0.0121 0.0611 0.098
Trichomonas vaginalis CMGC family protein kinase 0.01 0.04 0.0639
Loa Loa (eye worm) AUR protein kinase 0.0146 0.0874 0.0933
Plasmodium vivax unspecified product 0.01 0.04 0.4168
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0653 0.6184 1
Brugia malayi casein kinase I 0.0109 0.0489 0.0532
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0333 0.2831 0.3076
Echinococcus multilocularis roundabout 2 0.0139 0.0803 0.0948
Leishmania major casein kinase II, putative 0.01 0.04 0.0347
Echinococcus multilocularis 0.0121 0.061 0.0713
Echinococcus multilocularis protein kinase c epsilon type 0.0197 0.1413 0.1692
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0154 0.0963 0.1143
Schistosoma mansoni serine/threonine protein kinase 0.012 0.06 0.0961
Echinococcus multilocularis titin 0.0071 0.0088 0.0077
Schistosoma mansoni tyrosine kinase 0.0145 0.0871 0.14
Echinococcus multilocularis raf serine:threonine protein kinase 0.0089 0.028 0.031
Trichomonas vaginalis AGC family protein kinase 0.0259 0.2062 0.3329
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0101 0.0408 0.1214
Entamoeba histolytica protein kinase, putative 0.0083 0.0222 0.0319
Leishmania major casein kinase, putative 0.0109 0.0489 0.0496
Leishmania major protein kinase A catalytic subunit 0.0113 0.0535 0.0573
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0145 0.0866 0.1025
Echinococcus granulosus nervana 2 0.0096 0.0354 0.0298
Entamoeba histolytica protein kinase, putative 0.0083 0.0222 0.0319
Trypanosoma brucei serine/arginine-rich protein specific kinase SRPK, putative 0.0083 0.0222 0.005
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0233 0.1791 0.2153
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0139 0.0806 0.1025
Schistosoma mansoni serine/threonine protein kinase 0.0119 0.0595 0.0954
Plasmodium vivax calcium-dependent protein kinase, putative 0.0101 0.0408 0.4247
Schistosoma mansoni serine/threonine protein kinase 0.009 0.0288 0.0456
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.0367 0.3188 0.3452
Brugia malayi Protein kinase domain containing protein 0.0449 0.405 0.4402
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0113 0.0535 0.048
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0101 0.0408 0.036
Echinococcus multilocularis epidermal growth factor receptor 0.0612 0.575 0.6983
Plasmodium falciparum serine/threonine protein kinase, putative 0.0146 0.0874 0.889
Trichomonas vaginalis CMGC family protein kinase 0.0139 0.0806 0.1297
Trichomonas vaginalis AGC family protein kinase 0.0136 0.0777 0.1249
Toxoplasma gondii histone kinase SNF1, putative 0.009 0.0288 0.0541
Onchocerca volvulus 0.0193 0.1372 0.2197
Echinococcus granulosus aurora kinase A 0.0146 0.0874 0.0821
Loa Loa (eye worm) TK/FER protein kinase 0.0104 0.0441 0.0461
Entamoeba histolytica protein kinase, putative 0.0259 0.2062 0.3306
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0159 0.1017 0.1377
Loa Loa (eye worm) hypothetical protein 0.0143 0.0842 0.0897
Echinococcus granulosus dual specificity 0.0139 0.0806 0.0753
Entamoeba histolytica protein kinase, putative 0.0146 0.0874 0.1378
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0237 0.1828 0.2198
Toxoplasma gondii CMGC kinase, CK2 family 0.01 0.04 0.1171
Trypanosoma cruzi cdc2-related kinase 3 0.0119 0.0595 0.0754
Schistosoma mansoni tyrosine kinase 0.0145 0.0871 0.14
Loa Loa (eye worm) TK/EPH protein kinase 0.0129 0.0695 0.0738
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0138 0.0797 0.1087
Loa Loa (eye worm) hypothetical protein 0.0139 0.0799 0.0851
Echinococcus granulosus calcium:calmodulin dependent protein kinase I 0.0071 0.0094 0.0036
Schistosoma mansoni serine/threonine protein kinase 0.0071 0.0094 0.0142
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0081 0.0192 0.0086
Loa Loa (eye worm) hypothetical protein 0.0293 0.2414 0.2609
Entamoeba histolytica hypothetical protein 0.038 0.3322 0.5353
Echinococcus granulosus growth factor receptor bound protein 2 0.01 0.0398 0.0342
Trichomonas vaginalis CMGC family protein kinase 0.01 0.04 0.0639
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0288 0.0458
Trichomonas vaginalis CAMK family protein kinase 0.0653 0.6184 1
Loa Loa (eye worm) camk/dcamkl protein kinase 0.0151 0.093 0.0994
Echinococcus multilocularis tyrosine protein kinase 0.0287 0.2349 0.2834
Brugia malayi Variant SH3 domain containing protein 0.0098 0.0377 0.0409
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.01 0.04 0.0416
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0176 0.1191 0.1278
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0129 0.0703 0.6664
Schistosoma mansoni tyrosine kinase 0.0233 0.1791 0.2889
Echinococcus granulosus titin 0.0071 0.0088 0.0031
Giardia lamblia Kinase, CK1 Casein kinase 0.0109 0.0489 0.0448
Entamoeba histolytica protein kinase, putative 0.0074 0.0119 0.0152
Entamoeba histolytica protein kinase domain containing protein 0.01 0.04 0.0608
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0197 0.1413 0.1519
Schistosoma mansoni adapter molecule crk 0.0098 0.0377 0.06
Loa Loa (eye worm) hypothetical protein 0.036 0.3119 0.3377
Loa Loa (eye worm) hypothetical protein 0.0084 0.0224 0.0224
Trichomonas vaginalis STE family protein kinase 0.0136 0.0777 0.1249
Echinococcus multilocularis growth factor receptor bound protein 2 0.0098 0.0377 0.0428
Brugia malayi hypothetical protein 0.0112 0.0517 0.0561
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0083 0.0222 0.005
Trichomonas vaginalis CMGC family protein kinase 0.01 0.04 0.0639
Plasmodium falciparum glycogen synthase kinase 3 0.0129 0.0699 0.66
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0154 0.096 0.1281
Onchocerca volvulus Tyrosine kinase homolog 0.0554 0.5148 0.832
Loa Loa (eye worm) thyroid receptor interactor 0.0117 0.0571 0.0603
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0192 0.1361 0.1629
Echinococcus granulosus fibroblast growth factor receptor 4 0.0245 0.1915 0.1868
Echinococcus multilocularis cyclin dependent kinase 0.0119 0.0595 0.0695
Echinococcus multilocularis serine:threonine protein kinase 3 0.0257 0.2039 0.2455
Echinococcus granulosus NCK adaptor protein 0.0098 0.0377 0.0321
Entamoeba histolytica PH domain containing protein kinase, putative 0.0138 0.0797 0.1252
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0434 0.389 0.4714
Echinococcus granulosus cGMP dependent protein kinase 1 0.0135 0.076 0.0707
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0235 0.181 0.1763
Plasmodium vivax casein kinase 1, putative 0.0109 0.0489 0.5099
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0129 0.0699 0.0925
Giardia lamblia Kinase, CMGC CLK 0.0154 0.096 0.1237
Schistosoma mansoni serine/threonine protein kinase 0.0154 0.0963 0.1548
Schistosoma mansoni serine/threonine protein kinase 0.009 0.0292 0.0462
Loa Loa (eye worm) TK/FER protein kinase 0.0104 0.0441 0.0461
Loa Loa (eye worm) hypothetical protein 0.036 0.3119 0.3377
Trichomonas vaginalis CAMK family protein kinase 0.0653 0.6184 1
Plasmodium vivax protein kinase Crk2 0.0119 0.0595 0.6204
Echinococcus granulosus maternal embryonic leucine zipper kinase 0.0115 0.0556 0.0501
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0288 0.0458
Loa Loa (eye worm) hypothetical protein 0.0102 0.0414 0.0431
Echinococcus multilocularis dual specificity protein kinase clk2 0.0154 0.096 0.1139
Onchocerca volvulus 0.0104 0.0441 0.0687
Schistosoma mansoni serine/threonine protein kinase 0.009 0.0288 0.0456
Schistosoma mansoni serine/threonine protein kinase 0.0264 0.2116 0.3416
Schistosoma mansoni serine/threonine protein kinase 0.0197 0.1413 0.2277
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.0139 0.0806 0.0859
Leishmania major protein kinase, putative 0.0154 0.096 0.1281
Schistosoma mansoni serine/threonine protein kinase 0.0135 0.0763 0.1225
Entamoeba histolytica serine/threonine protein kinase, putative 0.0653 0.6184 1
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0235 0.181 0.2177
Onchocerca volvulus 0.0292 0.2403 0.3869
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0186 0.1296 0.1392
Echinococcus granulosus protein tyrosine kinase 0.0553 0.5134 0.5106
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0109 0.0489 0.0578
Brugia malayi Hr1 repeat family protein 0.0284 0.2318 0.2519
Brugia malayi Serine/threonine-protein kinase SULU 0.0222 0.1677 0.1822
Schistosoma mansoni serine/threonine protein kinase 0.0653 0.6184 1
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0099 0.0384 0.0612
Brugia malayi Protein kinase domain 0.0086 0.0252 0.0274
Onchocerca volvulus 0.0104 0.0441 0.0687
Schistosoma mansoni serine/threonine protein kinase 0.0135 0.076 0.1221
Loa Loa (eye worm) hypothetical protein 0.0232 0.1773 0.1912
Brugia malayi Immunoglobulin I-set domain containing protein 0.0634 0.5985 0.6504
Echinococcus granulosus activin receptor type 0.0081 0.0192 0.0135
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0101 0.0408 0.0466
Echinococcus multilocularis epidermal growth factor receptor 0.0404 0.3574 0.4328
Trichomonas vaginalis STE family protein kinase 0.0086 0.0252 0.04
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0096 0.0354 0.04
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.06 0.5627 0.6107
Brugia malayi Protein kinase domain containing protein 0.0104 0.0441 0.0479
Schistosoma mansoni tyrosine kinase 0.0356 0.3079 0.4975
Trypanosoma cruzi Protein kinase B 0.0138 0.0797 0.1087
Schistosoma mansoni protein kinase 0.0065 0.0026 0.0032
Schistosoma mansoni serine/threonine protein kinase 0.0109 0.0489 0.0782
Trichomonas vaginalis CMGC family protein kinase 0.009 0.0292 0.0464
Trichomonas vaginalis CMGC family protein kinase 0.0139 0.0806 0.1297
Entamoeba histolytica protein kinase, putative 0.0135 0.0762 0.1196
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.0448 0.4043 0.4383
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0098 0.0377 0.06
Schistosoma mansoni protein kinase 0.0086 0.0252 0.0399
Echinococcus multilocularis Immunoglobulin 0.0083 0.022 0.0238
Echinococcus granulosus mitogen activated protein kinase 11 0.0159 0.1017 0.0965
Schistosoma mansoni tyrosine kinase 0.0449 0.405 0.6547
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0233 0.1791 0.2153
Brugia malayi Protein kinase domain containing protein 0.0287 0.2349 0.2553
Schistosoma mansoni protein kinase 0.0109 0.0489 0.0782
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0218 0.1629 0.1754
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0288 0.0458
Plasmodium falciparum calcium-dependent protein kinase 2 0.0101 0.0408 0.281
Schistosoma mansoni vam6/vps39 related 0.0112 0.0517 0.0827
Brugia malayi Protein kinase domain containing protein 0.0104 0.0441 0.0479
Trichomonas vaginalis AGC family protein kinase 0.0082 0.0205 0.0324
Echinococcus granulosus calcium activated potassium channel 0.0135 0.0763 0.0709
Onchocerca volvulus 0.0112 0.0517 0.0809
Echinococcus granulosus serine threonine protein kinase nrc 0.0129 0.0703 0.0649
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0146 0.0874 0.9112
Loa Loa (eye worm) hypothetical protein 0.0126 0.0671 0.0712
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.0153 0.0954 0.102
Brugia malayi serine/threonine-protein kinase 6 0.0146 0.0874 0.095
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.0201 0.1452 0.1402
Brugia malayi protein unc-22 0.0071 0.0088 0.0096
Schistosoma mansoni vesicular amine transporter 0.0083 0.022 0.0347
Onchocerca volvulus 0.009 0.0292 0.0445
Trichomonas vaginalis STE family protein kinase 0.0065 0.0026 0.0033
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0288 0.0458
Schistosoma mansoni serine/threonine protein kinase 0.0255 0.202 0.3259
Echinococcus granulosus protein kinase c iota type 0.0279 0.2267 0.2222
Schistosoma mansoni growth factor receptor-bound protein 0.0098 0.0377 0.06
Loa Loa (eye worm) hypothetical protein 0.009 0.0288 0.0294
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0086 0.0252 0.0277
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0233 0.1791 0.2153
Echinococcus multilocularis mitogen activated protein kinase 0.0084 0.0229 0.0248
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0102 0.0412 0.0356
Onchocerca volvulus 0.0143 0.0842 0.1336
Echinococcus granulosus serine:threonine protein kinase N2 0.0284 0.2318 0.2273
Schistosoma mansoni tyrosine kinase 0.0612 0.575 0.9298
Trichomonas vaginalis CMGC family protein kinase 0.0084 0.0229 0.0362
Plasmodium falciparum calcium-dependent protein kinase 1 0.0101 0.0408 0.281
Echinococcus granulosus tyrosine protein kinase Fyn 0.0233 0.1791 0.1743
Giardia lamblia Kinase, CMGC GSK 0.0129 0.0699 0.0799
Echinococcus granulosus casein kinase I alpha 0.0109 0.0489 0.0434
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0084 0.0229 0.0147
Loa Loa (eye worm) hypothetical protein 0.0208 0.1525 0.1641
Giardia lamblia Kinase, STE STE20 0.0085 0.0238 0.0027
Trichomonas vaginalis CMGC family protein kinase 0.0139 0.0806 0.1297
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0082 0.0205 0.0219
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0145 0.0867 0.1027
Brugia malayi Protein kinase domain containing protein 0.06 0.5627 0.6115
Trichomonas vaginalis CMGC family protein kinase 0.0084 0.0229 0.0362
Giardia lamblia Kinase, NEK 0.0136 0.0777 0.093
Schistosoma mansoni cell adhesion molecule 0.0117 0.0576 0.0922
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0154 0.096 0.1281
Loa Loa (eye worm) hypothetical protein 0.0112 0.0517 0.0543
Schistosoma mansoni serine/threonine protein kinase 0.0119 0.0595 0.0954
Echinococcus multilocularis dual specificity 0.0139 0.0806 0.0952
Trypanosoma brucei Casein kinase II 0.01 0.04 0.0347
Brugia malayi Furin-like cysteine rich region family protein 0.0612 0.575 0.6249
Trichomonas vaginalis AGC family protein kinase 0.0259 0.2062 0.3329
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0109 0.0489 0.0514
Brugia malayi casein kinase 1, delta 0.0109 0.0489 0.0532
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0154 0.096 0.1026
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0112 0.0517 0.0624
Echinococcus granulosus c src tyrosine kinase 0.0145 0.0871 0.0818
Echinococcus granulosus MAP kinase activated protein kinase 2 0.0394 0.3475 0.3437
Echinococcus multilocularis phosphorylase kinase gamma subunit 0.0164 0.1069 0.1272
Trichomonas vaginalis CAMK family protein kinase 0.0653 0.6184 1
Trichomonas vaginalis AGC family protein kinase 0.0146 0.0874 0.1407
Leishmania major protein kinase A catalytic subunit isoform 2 0.0113 0.0535 0.0573
Echinococcus granulosus Vam6:Vps39 protein 0.0112 0.0517 0.0461
Trichomonas vaginalis CMGC family protein kinase 0.009 0.0292 0.0464
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0407 0.3613 0.4376
Brugia malayi Tyrosine-protein kinase abl-1 0.0128 0.0688 0.0747
Echinococcus granulosus protein kinase C gamma type 0.0195 0.139 0.134
Echinococcus granulosus casein kinase I gamma 0.0213 0.1583 0.1534
Entamoeba histolytica protein kinase , putative 0.0146 0.0874 0.1378
Loa Loa (eye worm) TK/INSR protein kinase 0.0449 0.405 0.4391
Plasmodium falciparum calcium-dependent protein kinase 4 0.0101 0.0408 0.281
Entamoeba histolytica protein kinase, putative 0.0146 0.0874 0.1378
Echinococcus multilocularis tyrosine protein kinase HCK 0.0135 0.0762 0.0898
Brugia malayi Protein kinase domain containing protein 0.0104 0.0441 0.0479
Trichomonas vaginalis STE family protein kinase 0.0086 0.0252 0.04
Plasmodium falciparum tyrosine kinase-like protein, putative 0.0081 0.02 0.0109
Entamoeba histolytica protein kinase domain containing protein 0.0203 0.1472 0.2348
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0101 0.0408 0.0425
Entamoeba histolytica protein kinase, putative 0.0139 0.0806 0.1268
Entamoeba histolytica protein kinase, putative 0.0071 0.0094 0.0111
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0159 0.1017 0.1451
Brugia malayi Protein kinase domain containing protein 0.0154 0.0963 0.1046
Echinococcus multilocularis expressed protein 0.0083 0.0222 0.0239
Schistosoma mansoni tyrosine kinase 0.0254 0.2011 0.3245
Giardia lamblia Kinase, AGC PKA 0.0113 0.0535 0.0525
Giardia lamblia Kinase, CMGC DYRK 0.0139 0.0806 0.098
Giardia lamblia Kinase, CMGC CK2 0.01 0.04 0.0298
Echinococcus multilocularis cyclin dependent kinase 5 0.0119 0.0595 0.0695
Trichomonas vaginalis CAMK family protein kinase 0.0653 0.6184 1
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0113 0.0535 0.0654
Leishmania major protein kinase, putative 0.0101 0.0408 0.036
Echinococcus granulosus casein kinase I alpha 0.0109 0.0489 0.0434
Brugia malayi Protein kinase domain containing protein 0.0083 0.0222 0.0241
Loa Loa (eye worm) hypothetical protein 0.0239 0.1855 0.2001
Echinococcus granulosus tyrosine protein kinase Fyn 0.0233 0.1791 0.1743
Trichomonas vaginalis AGC family protein kinase 0.0154 0.0963 0.155
Plasmodium falciparum calcium-dependent protein kinase 3 0.0101 0.0408 0.281
Brugia malayi Protein kinase domain containing protein 0.0217 0.1622 0.1762
Schistosoma mansoni protein kinase 0.0236 0.1818 0.2932
Echinococcus multilocularis casein kinase I gamma 0.0213 0.1583 0.1899
Loa Loa (eye worm) AGC/NDR protein kinase 0.0154 0.0963 0.1029
Schistosoma mansoni hypothetical protein 0.0112 0.0517 0.0827
Trichomonas vaginalis CK1 family protein kinase 0.0109 0.0489 0.0784
Brugia malayi Protein kinase domain containing protein 0.009 0.0292 0.0317
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0412 0.366 0.3623
Entamoeba histolytica protein kinase domain containing protein 0.0146 0.0874 0.1378
Brugia malayi Protein kinase domain containing protein 0.0259 0.2062 0.224
Echinococcus granulosus casein kinase I delta 0.0109 0.0489 0.0434
Plasmodium falciparum protein serine/threonine kinase-1 0.0154 0.096 1
Echinococcus granulosus tyrosine protein kinase 0.0287 0.2349 0.2305
Echinococcus granulosus phosphorylase kinase gamma subunit 0.0164 0.1069 0.1017
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0288 0.0458
Loa Loa (eye worm) hypothetical protein 0.0112 0.0517 0.0543
Leishmania major protein kinase, putative 0.0085 0.0238 0.0078
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0216 0.1612 0.1935
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0653 0.6184 0.6714
Echinococcus multilocularis nervana 2 0.0096 0.0354 0.04
Brugia malayi Immunoglobulin I-set domain containing protein 0.0267 0.2142 0.2328
Loa Loa (eye worm) TK protein kinase 0.0192 0.1361 0.1463
Loa Loa (eye worm) hypothetical protein 0.0121 0.061 0.0645
Brugia malayi Protein kinase domain containing protein 0.0559 0.5197 0.5648
Trypanosoma cruzi casein kinase II, putative 0.01 0.04 0.0431
Entamoeba histolytica protein kinase domain containing protein 0.0129 0.0699 0.1093
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0084 0.0229 0.0061
Brugia malayi Immunoglobulin I-set domain containing protein 0.0099 0.0384 0.0417
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.009 0.0288 0.016
Trichomonas vaginalis CAMK family protein kinase 0.0115 0.0556 0.0892
Echinococcus granulosus protein kinase 0.0153 0.0954 0.0902
Schistosoma mansoni serine/threonine protein kinase 0.0082 0.0205 0.0322
Loa Loa (eye worm) protein kinase domain-containing protein 0.0213 0.1583 0.1704
Echinococcus granulosus protein kinase c epsilon type 0.0197 0.1413 0.1363
Echinococcus multilocularis 0.0173 0.1164 0.1389
Echinococcus granulosus tyrosine protein kinase ABL1 0.0312 0.261 0.2567
Onchocerca volvulus 0.0104 0.0441 0.0687
Giardia lamblia Kinase, AGC PKA 0.0129 0.0703 0.0808
Mycobacterium ulcerans hypothetical protein 0.0102 0.0411 0.5
Entamoeba histolytica protein kinase domain containing protein 0.0081 0.0192 0.027
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0129 0.0699 0.0846
Entamoeba histolytica protein kinase, putative 0.0259 0.2062 0.3306
Echinococcus granulosus cyclin dependent kinase 5 0.0119 0.0595 0.0541
Echinococcus granulosus CDC7 cell division cycle 7 0.009 0.0292 0.0235
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0146 0.0874 0.1035
Schistosoma mansoni tyrosine kinase 0.0318 0.2674 0.4318
Echinococcus granulosus Protein kinase C brain isozyme 0.0237 0.1828 0.178
Trichomonas vaginalis AGC family protein kinase 0.0082 0.0205 0.0324
Echinococcus multilocularis serine:threonine kinase SAD 1 0.009 0.0288 0.032
Brugia malayi Protein kinase domain containing protein 0.0213 0.1583 0.172
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0164 0.1066 0.1141
Schistosoma mansoni serine/threonine protein kinase 0.0123 0.0631 0.1012
Brugia malayi Tyrosine-protein kinase abl-1 0.0225 0.17 0.1847
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0136 0.0777 0.3292
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0146 0.0874 0.0821
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0071 0.0088 0.0077
Onchocerca volvulus 0.0184 0.1279 0.2046
Trichomonas vaginalis CMGC family protein kinase 0.0084 0.0229 0.0362
Echinococcus granulosus tyrosine protein kinase shark 0.0318 0.2674 0.2631
Trichomonas vaginalis CMGC family protein kinase 0.01 0.04 0.0639
Echinococcus multilocularis serine threonine protein kinase 0.0195 0.139 0.1665
Schistosoma mansoni serine/threonine protein kinase 0.0237 0.1828 0.2949
Trichomonas vaginalis AGC family protein kinase 0.0175 0.1176 0.1896
Echinococcus granulosus tyrosine protein kinase HCK 0.0135 0.0762 0.0708
Loa Loa (eye worm) CMGC/SRPK protein kinase 0.0083 0.0222 0.0223
Echinococcus multilocularis Immunoglobulin 0.0083 0.022 0.0238
Trypanosoma brucei cdc2-related kinase 3 0.0119 0.0595 0.0673
Trichomonas vaginalis CAMK family protein kinase 0.0653 0.6184 1
Loa Loa (eye worm) CDC7 protein kinase 0.009 0.0292 0.0298
Loa Loa (eye worm) hypothetical protein 0.0083 0.022 0.0221
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0245 0.1915 0.2305
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.0217 0.1622 0.1747
Entamoeba histolytica protein kinase, putative 0.0082 0.0205 0.0291
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0288 0.0458
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0082 0.0205 0.0204
Onchocerca volvulus 0.009 0.0292 0.0445
Schistosoma mansoni serine/threonine kinase 0.0154 0.0963 0.1548
Echinococcus multilocularis protein kinase shaggy 0.0129 0.0699 0.0821
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.009 0.0288 0.016
Brugia malayi phosphoinositide-dependent protein kinase I 0.0082 0.0205 0.0223
Loa Loa (eye worm) TK/EGFR protein kinase 0.0612 0.575 0.6242
Entamoeba histolytica protein kinase, putative 0.0123 0.0631 0.0983
Echinococcus multilocularis serine:threonine protein kinase N2 0.0284 0.2318 0.2796
Echinococcus multilocularis casein kinase i 0.0109 0.0489 0.0565
Giardia lamblia Kinase, CAMK CAMKL 0.009 0.0288 0.011
Loa Loa (eye worm) TK/FER protein kinase 0.0104 0.0441 0.0461
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0113 0.0535 0.0573
Loa Loa (eye worm) hypothetical protein 0.0066 0.0041 0.0025
Echinococcus granulosus tyrosine kinase 0.0104 0.0441 0.0385
Trypanosoma cruzi casein kinase, putative 0.0109 0.0489 0.0578
Brugia malayi serine/threonine-protein kinase plk-2 0.0653 0.6184 0.672
Loa Loa (eye worm) AGC/PKA protein kinase 0.0113 0.0535 0.0563
Loa Loa (eye worm) AGC/AKT protein kinase 0.0259 0.2062 0.2226
Brugia malayi Protein kinase domain containing protein 0.0194 0.1379 0.1498
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0264 0.2116 0.2285
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0101 0.0408 0.0466
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0086 0.0252 0.0277
Entamoeba histolytica protein kinase, putative 0.0154 0.0963 0.1521
Trichomonas vaginalis AGC family protein kinase 0.0259 0.2062 0.3329
Trichomonas vaginalis STE family protein kinase 0.0085 0.0238 0.0378
Schistosoma mansoni serine/threonine protein kinase 0.0203 0.1472 0.2373
Onchocerca volvulus 0.0139 0.0799 0.1268
Entamoeba histolytica protein kinase domain containing protein 0.0129 0.0699 0.1093
Echinococcus multilocularis casein kinase I delta 0.0109 0.0489 0.0565
Schistosoma mansoni protein kinase 0.0086 0.0252 0.0399
Loa Loa (eye worm) TK/FER protein kinase 0.0104 0.0441 0.0461
Schistosoma mansoni serine/threonine-protein kinase 0.0138 0.0797 0.128
Schistosoma mansoni vav2 0.0108 0.0478 0.0764
Trypanosoma brucei protein kinase, putative 0.0084 0.0229 0.0061
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0238 0.1842 0.2215
Brugia malayi cell division control protein 2 homolog 0.0119 0.0595 0.0647
Brugia malayi Homeodomain interacting protein kinase protein 1 0.0203 0.1472 0.1599
Echinococcus multilocularis casein kinase I alpha 0.0109 0.0489 0.0565
Schistosoma mansoni serine/threonine protein kinase 0.0164 0.1069 0.172
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0113 0.0535 0.1931
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.0941 0.9202 1
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0154 0.096 0.1357
Entamoeba histolytica hypothetical protein 0.0123 0.0631 0.0983
Brugia malayi Protein kinase domain containing protein 0.0941 0.9202 1
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0084 0.0229 0.0147
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0113 0.0535 0.5575
Brugia malayi C1-like domain containing protein 0.0218 0.1629 0.177
Echinococcus granulosus defective proboscis extension response 0.0083 0.022 0.0163
Toxoplasma gondii AGC kinase 0.0113 0.0535 0.1931
Loa Loa (eye worm) hypothetical protein 0.0083 0.022 0.0221
Brugia malayi Variant SH3 domain containing protein 0.0067 0.0054 0.0058
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.009 0.0288 0.016
Brugia malayi Protein kinase domain containing protein 0.0123 0.0631 0.0686
Onchocerca volvulus 0.0325 0.2753 0.4436
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0136 0.0777 0.8094
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.06 0.5627 0.6107
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0653 0.6184 0.7512
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0129 0.0699 0.0741
Onchocerca volvulus 0.0104 0.0441 0.0687
Echinococcus granulosus tyrosine protein kinase Lyn 0.0267 0.214 0.2094
Schistosoma mansoni serine/threonine protein kinase 0.0284 0.2318 0.3743
Echinococcus granulosus serine:threonine protein kinase TAO1 0.0222 0.1677 0.1628
Echinococcus granulosus dual specificity 0.0139 0.0806 0.0753
Echinococcus granulosus neuroglian 0.0105 0.0447 0.0392
Brugia malayi Protein kinase domain containing protein 0.0104 0.0441 0.0479
Schistosoma mansoni serine/threonine protein kinase 0.0146 0.0874 0.1406
Echinococcus multilocularis tyrosine protein kinase Srms 0.0192 0.1361 0.1629
Schistosoma mansoni titin 0.0071 0.0088 0.0133
Echinococcus granulosus serine:threonine protein kinase 0.0114 0.0546 0.0491
Echinococcus multilocularis tyrosine protein kinase Blk 0.0192 0.1361 0.1629
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0218 0.1629 0.177
Trichomonas vaginalis CAMK family protein kinase 0.0217 0.1622 0.2617
Trypanosoma cruzi casein kinase, putative 0.0109 0.0489 0.0578
Loa Loa (eye worm) CAMK protein kinase 0.0071 0.0088 0.0077
Toxoplasma gondii AGC kinase 0.025 0.1968 1
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0353 0.304 0.2999
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0084 0.0229 0.0147
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.0112 0.0517 0.0599
Loa Loa (eye worm) hypothetical protein 0.0104 0.0441 0.0461
Brugia malayi Protein kinase domain containing protein 0.0353 0.304 0.3303
Echinococcus granulosus epidermal growth factor receptor 0.0404 0.3574 0.3536
Onchocerca volvulus 0.0485 0.4427 0.7151
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0101 0.0408 0.0466
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0331 0.2818 0.3049
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0412 0.366 0.4433
Loa Loa (eye worm) hypothetical protein 0.0102 0.0412 0.0429
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0288 0.0458
Echinococcus multilocularis protein tyrosine kinase 0.0553 0.5134 0.6232
Loa Loa (eye worm) STE/STE20/SLK protein kinase 0.0193 0.1369 0.1472
Schistosoma mansoni tyrosine kinase 0.0233 0.1791 0.2889
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0089 0.028 0.0285
Loa Loa (eye worm) TK/FER protein kinase 0.0407 0.3613 0.3915
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0123 0.0631 0.0668
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0159 0.1017 0.1088
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0147 0.0888 0.1051
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0186 0.1296 0.1549
Schistosoma mansoni serine/threonine protein kinase 0.0071 0.0088 0.0133
Echinococcus multilocularis calcium:calmodulin dependent protein kinase I 0.0071 0.0094 0.0083
Trypanosoma brucei cdc2-related kinase 1 0.0119 0.0595 0.0673
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.0222 0.1677 0.2014
Brugia malayi protein-tyrosine kinase 0.0192 0.1361 0.1479
Trichomonas vaginalis AGC family protein kinase 0.0146 0.0874 0.1407
Trypanosoma cruzi cdc2-related kinase 1 0.0119 0.0595 0.0754
Echinococcus multilocularis N chimaerin 0.0099 0.0384 0.0438
Trichomonas vaginalis CAMK family protein kinase 0.0115 0.0556 0.0892
Trypanosoma cruzi SNF1-related protein kinases, putative 0.009 0.0288 0.0245
Brugia malayi Protein kinase domain containing protein 0.0284 0.2316 0.2517
Echinococcus granulosus Glutaredoxin protein 5 0.0096 0.0354 0.0298
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0141 0.0827 0.133
Schistosoma mansoni serine/threonine protein kinase 0.0083 0.0222 0.035
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0129 0.0703 0.7331
Brugia malayi protein kinase C3,putative 0.0158 0.1002 0.1089
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0192 0.1361 0.1311
Echinococcus multilocularis casein kinase ii subunit alpha 0.01 0.04 0.0456
Loa Loa (eye worm) hypothetical protein 0.0193 0.1372 0.1475
Onchocerca volvulus 0.0104 0.0441 0.0687
Echinococcus granulosus serine:threonine protein kinase Chk2 0.0071 0.0094 0.0036
Schistosoma mansoni serine/threonine protein kinase 0.0201 0.1452 0.2341
Schistosoma mansoni protein kinase 0.0146 0.0874 0.1406
Schistosoma mansoni serine/threonine protein kinase 0.0135 0.0763 0.1225
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0101 0.0408 0.0443
Trypanosoma brucei casein kinase I, isoform 2 0.0109 0.0489 0.0496
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0233 0.1791 0.1743
Schistosoma mansoni nck2/grb4 0.0098 0.0377 0.06
Echinococcus granulosus dual specificity 0.0139 0.0806 0.0753
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0096 0.0354 0.0298
Entamoeba histolytica protein kinase, putative 0.0101 0.0408 0.062
Brugia malayi ribosomal protein S6 kinase alpha 3 0.0117 0.0577 0.0627
Brugia malayi Variant SH3 domain containing protein 0.0098 0.0377 0.0409
Echinococcus multilocularis serine:threonine protein kinase Chk2 0.0071 0.0094 0.0083
Echinococcus multilocularis hypothetical protein 0.0102 0.0414 0.0473
Trypanosoma brucei STE20-like serine/threonine-protein kinase 1, putative 0.0085 0.0238 0.0078
Echinococcus granulosus casein kinase I alpha 0.0109 0.0489 0.0434
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0086 0.0252 0.0277
Entamoeba histolytica protein kinase, putative 0.0086 0.0252 0.0368
Entamoeba histolytica protein kinase, putative 0.0074 0.0119 0.0152
Trichomonas vaginalis CAMK family protein kinase 0.0315 0.265 0.4281
Entamoeba histolytica protein kinase 2, putative 0.0129 0.0703 0.1101
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.0139 0.0806 0.1025
Brugia malayi Protein kinase domain containing protein 0.0164 0.1069 0.1161
Loa Loa (eye worm) hypothetical protein 0.0099 0.0384 0.0399
Echinococcus multilocularis casein kinase I alpha 0.0109 0.0489 0.0565
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0465 0.4214 0.5109
Schistosoma mansoni serine/threonine protein kinase 0.0186 0.1296 0.2088
Toxoplasma gondii cell-cycle-associated protein kinase SRPK, putative 0.0083 0.0222 0.017
Brugia malayi protein kinase C II. 0.0197 0.1413 0.1535
Brugia malayi Doublecortin family protein 0.0151 0.093 0.1011
Loa Loa (eye worm) hypothetical protein 0.0139 0.0799 0.0851
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0113 0.0535 0.4469
Echinococcus multilocularis cyclin dependent kinase 1 0.0119 0.0595 0.0695
Echinococcus granulosus mitogen activated protein kinase 0.0084 0.0229 0.0172
Echinococcus multilocularis maternal embryonic leucine zipper kinase 0.0115 0.0556 0.0647
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0085 0.0238 0.0163
Schistosoma mansoni serine/threonine protein kinase 0.0154 0.0963 0.1548
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0154 0.0963 0.091
Entamoeba histolytica protein kinase, putative 0.0091 0.0297 0.044
Plasmodium falciparum casein kinase 1 0.0109 0.0489 0.3874
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.0257 0.2039 0.22
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0084 0.0229 0.0147
Schistosoma mansoni serine/threonine-protein kinase 0.0138 0.0797 0.128
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0098 0.0377 0.0391
Loa Loa (eye worm) hypothetical protein 0.06 0.5627 0.6107
Giardia lamblia Kinase, NEK 0.0136 0.0777 0.093
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0112 0.0517 0.0827
Schistosoma mansoni serine/threonine protein kinase 0.0113 0.0535 0.0856
Echinococcus multilocularis dual specificity 0.0123 0.0631 0.0739
Loa Loa (eye worm) hypothetical protein 0.0123 0.0639 0.0676
Echinococcus granulosus expressed protein 0.0083 0.0222 0.0165
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0101 0.0408 0.0352
Schistosoma mansoni hypothetical protein 0.0102 0.0414 0.066
Echinococcus multilocularis aurora kinase A 0.0146 0.0874 0.1035
Trichomonas vaginalis CMGC family protein kinase 0.0119 0.0595 0.0955
Echinococcus granulosus c-Jun N-terminal kinases 0.0264 0.2116 0.207
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0101 0.0408 0.0425
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0145 0.0867 0.0814
Brugia malayi SH2 domain containing protein 0.0407 0.3613 0.3927
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.0114 0.0546 0.0576
Loa Loa (eye worm) TK/FER protein kinase 0.0104 0.0441 0.0461
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0288 0.0458
Loa Loa (eye worm) hypothetical protein 0.0089 0.0282 0.0288
Schistosoma mansoni serine/threonine protein kinase 0.0154 0.096 0.1544
Loa Loa (eye worm) AUR protein kinase 0.0146 0.0874 0.0933
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0113 0.0535 0.0654
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0119 0.0595 0.0673
Trypanosoma cruzi aurora B kinase, putative 0.0146 0.0874 0.1215
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.0139 0.0806 0.3459
Trichomonas vaginalis AGC family protein kinase 0.0082 0.0205 0.0324
Loa Loa (eye worm) TK/ABL protein kinase 0.0312 0.261 0.2822
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0101 0.0408 0.4247
Echinococcus granulosus serine:threonine protein kinase 0.0114 0.0546 0.0491
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.009 0.0288 0.0294
Echinococcus multilocularis STE20 serine:threonine protein kinase 0.0494 0.4522 0.5485
Loa Loa (eye worm) hypothetical protein 0.0112 0.0517 0.0543
Loa Loa (eye worm) AGC/PKN protein kinase 0.0284 0.2318 0.2505
Echinococcus granulosus tyrosine protein kinase Blk 0.0192 0.1361 0.1311
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0201 0.1452 0.1562
Trypanosoma brucei polo-like protein kinase 0.0653 0.6184 1
Schistosoma mansoni tyrosine kinase 0.0356 0.3079 0.4975
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0083 0.022 0.0347
Schistosoma mansoni serine/threonine protein kinase 0.0135 0.076 0.1221
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.0222 0.1677 0.1806
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0634 0.5985 0.6497
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0154 0.0963 0.091
Echinococcus multilocularis 0.0153 0.0954 0.1133
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0081 0.02 0.0047
Trypanosoma brucei SNF1-related protein kinases, putative 0.009 0.0288 0.016
Echinococcus multilocularis nervana 2 0.0096 0.0354 0.04
Leishmania major protein kinase, putative 0.0154 0.096 0.1281
Echinococcus multilocularis CDC7 cell division cycle 7 0.009 0.0292 0.0324
Plasmodium vivax glycogen synthase kinase 3, putative 0.0129 0.0699 0.7279
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0135 0.076 0.0896
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0101 0.0408 0.0352
Echinococcus multilocularis calcium activated potassium channel 0.0135 0.0763 0.0899
Loa Loa (eye worm) TK protein kinase 0.0267 0.2142 0.2313
Schistosoma mansoni serine/threonine protein kinase 0.0216 0.1612 0.2599
Brugia malayi Stress-activated protein kinase jnk-1 0.0264 0.2116 0.23
Plasmodium falciparum calcium-dependent protein kinase 5 0.0101 0.0408 0.281
Echinococcus multilocularis NCK adaptor protein 0.01 0.0398 0.0454
Giardia lamblia Kinase, CMGC CDK 0.0119 0.0595 0.0626
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0069 0.0069 0.0053
Trichomonas vaginalis STE family protein kinase 0.0086 0.0252 0.04
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.025 0.1968 0.2124
Brugia malayi Protein kinase domain containing protein 0.0154 0.096 0.1043
Trichomonas vaginalis AGC family protein kinase 0.0259 0.2062 0.3329
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0238 0.1842 0.1986
Echinococcus granulosus tyrosine kinase 0.0192 0.1361 0.1311
Echinococcus granulosus tyrosine protein kinase Src64B 0.0233 0.1791 0.1743
Echinococcus multilocularis rac serine:threonine kinase 0.0138 0.0797 0.0941
Onchocerca volvulus 0.0076 0.014 0.0198
Schistosoma mansoni serine/threonine protein kinase 0.0235 0.181 0.2921
Trichomonas vaginalis CMGC family protein kinase 0.0119 0.0595 0.0955
Entamoeba histolytica serine/threonine-protein kinase 3, putative 0.0085 0.0238 0.0345
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0146 0.0874 0.1378
Trichomonas vaginalis CMGC family protein kinase 0.0139 0.0806 0.1297
Brugia malayi intracellular kinase 0.0129 0.0699 0.0759
Echinococcus granulosus casein kinase ii subunit alpha 0.01 0.04 0.0344
Loa Loa (eye worm) TK protein kinase 0.0135 0.0762 0.081
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0129 0.0703 0.0933
Echinococcus multilocularis mitogen activated protein kinase 3 0.0084 0.0229 0.0248
Loa Loa (eye worm) CAMK/PHK protein kinase 0.0164 0.1069 0.1145
Onchocerca volvulus 0.0104 0.0441 0.0687
Trichomonas vaginalis CAMK family protein kinase 0.0315 0.265 0.4281
Trichomonas vaginalis CMGC family protein kinase 0.0129 0.0699 0.1122
Brugia malayi Kinase associated domain 1 family protein 0.0102 0.0414 0.0449
Entamoeba histolytica protein kinase, putative 0.025 0.1968 0.3154
Schistosoma mansoni protein kinase 0.01 0.04 0.0638
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0069 0.0069 0.0011
Trichomonas vaginalis AGC family protein kinase 0.0146 0.0874 0.1407
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0113 0.0535 0.048
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0113 0.0535 0.0621
Schistosoma mansoni serine/threonine protein kinase 0.0101 0.0408 0.065
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0099 0.0384 0.0612
Giardia lamblia Kinase, CMGC GSK 0.0129 0.0699 0.0799
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0099 0.0384 0.0438
Schistosoma mansoni serine/threonine protein kinase 0.0235 0.181 0.2921
Schistosoma mansoni serine/threonine protein kinase 0.0477 0.434 0.7016
Entamoeba histolytica protein kinase, putative 0.0123 0.0631 0.0983
Giardia lamblia Kinase, CMGC CDK 0.0119 0.0595 0.0626
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0129 0.0699 0.0821
Echinococcus granulosus NDR protein kinase 0.0154 0.0963 0.091
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0353 0.304 0.3676
Brugia malayi Protein kinase domain containing protein 0.0191 0.1343 0.146
Echinococcus multilocularis casein kinase I delta 0.0109 0.0489 0.0565
Schistosoma mansoni atypical protein kinase C 0.0285 0.233 0.3762
Brugia malayi STE20-like kinase MST 0.0257 0.2039 0.2215
Echinococcus granulosus N chimaerin 0.0099 0.0384 0.0328
Brugia malayi putative serine/threonine kinase SADA gamma 0.009 0.0288 0.0313
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.009 0.0288 0.3
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.0139 0.0806 0.0876
Trichomonas vaginalis CAMK family protein kinase 0.0101 0.0408 0.0651
Echinococcus multilocularis death associated protein kinase 1 0.0848 0.8224 1
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.009 0.0288 0.0245
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0288 0.0458
Giardia lamblia Kinase, NEK 0.0136 0.0777 0.093
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0288 0.0458
Entamoeba histolytica casein kinase, putative 0.0109 0.0489 0.0753
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0288 0.0458
Echinococcus multilocularis calcium dependent protein kinase 0.0068 0.0058 0.0039
Loa Loa (eye worm) hypothetical protein 0.0143 0.0842 0.0897
Echinococcus multilocularis rho associated protein kinase 0.0325 0.2753 0.3326
Brugia malayi Protein kinase domain containing protein 0.0114 0.0546 0.0594
Brugia malayi P38 map kinase family protein 2 0.0159 0.1017 0.1105
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0353 0.304 0.329
Schistosoma mansoni kinase 0.0483 0.4401 0.7114
Echinococcus granulosus epidermal growth factor receptor 0.0612 0.575 0.5725
Onchocerca volvulus 0.0109 0.0489 0.0765
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0099 0.0384 0.0328
Brugia malayi serine/threonine kinase 12 0.0146 0.0874 0.095
Schistosoma mansoni serine/threonine protein kinase 0.0135 0.0763 0.1225
Schistosoma mansoni ephrin receptor 0.0111 0.0512 0.0818
Echinococcus multilocularis myosin iiia 0.0085 0.0238 0.0259
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0288 0.0458
Entamoeba histolytica cell division protein kinase 2, putative 0.0119 0.0595 0.0925
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0112 0.0517 0.0542
Trichomonas vaginalis AGC family protein kinase 0.0259 0.2062 0.3329
Loa Loa (eye worm) hypothetical protein 0.0184 0.1279 0.1373
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0233 0.1791 0.1743
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0216 0.1612 0.1563
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.0112 0.0517 0.0461
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0129 0.0703 0.0827
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0119 0.0595 0.0629
Trypanosoma cruzi serine/arginine-rich protein specific kinase SRPK, putative 0.0083 0.0222 0.0136
Brugia malayi Protein kinase domain containing protein 0.0193 0.1369 0.1488
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0113 0.0535 0.0654
Plasmodium vivax serine/threonine kinase-1, putative 0.0154 0.096 1
Brugia malayi hypothetical protein 0.0099 0.0384 0.0417
Entamoeba histolytica protein kinase, putative 0.0102 0.0421 0.0641
Entamoeba histolytica serine/threonine protein kinase STE20, putative 0.0085 0.0238 0.0345
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0104 0.0441 0.0675
Leishmania major protein kinase, putative 0.0146 0.0874 0.1139
Schistosoma mansoni serine/threonine protein kinase 0.009 0.0288 0.0456
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0119 0.0595 0.0673
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.01 0.04 0.4168
Loa Loa (eye worm) TK/FER protein kinase 0.0104 0.0441 0.0461
Schistosoma mansoni serine/threonine protein kinase 0.0216 0.1612 0.2599
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0238 0.1842 0.1794
Loa Loa (eye worm) TK/FER protein kinase 0.0104 0.0441 0.0461
Trypanosoma cruzi cdc2-related kinase 3 0.0119 0.0595 0.0754
Trichomonas vaginalis CAMK family protein kinase 0.0653 0.6184 1
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0154 0.0963 0.1143
Trypanosoma cruzi casein kinase, putative 0.0109 0.0489 0.0578
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0113 0.0535 0.048
Echinococcus granulosus nervana 2 0.0096 0.0354 0.0298
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0113 0.0535 0.0621
Echinococcus granulosus tyrosine protein kinase Fyn 0.0233 0.1791 0.1743
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0109 0.0489 0.0514
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0233 0.1791 0.2153
Schistosoma mansoni serine/threonine protein kinase 0.0113 0.0535 0.0856
Brugia malayi p70 ribosomal S6 kinase beta 0.025 0.1968 0.2139
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0081 0.0192 0.0086
Echinococcus granulosus cyclin dependent kinase 1 0.0119 0.0595 0.0541
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0353 0.304 0.329
Toxoplasma gondii aurora kinase 0.0146 0.0874 0.3842
Brugia malayi Protein kinase c protein 2 0.0116 0.0563 0.0612
Plasmodium falciparum cGMP-dependent protein kinase 0.0135 0.076 0.7406
Trichomonas vaginalis CMGC family protein kinase 0.01 0.04 0.0639
Echinococcus granulosus casein kinase i 0.0109 0.0489 0.0434
Schistosoma mansoni protein kinase 0.0153 0.0954 0.1535
Echinococcus multilocularis mitogen activated protein kinase 14 0.0159 0.1017 0.1209
Echinococcus granulosus cGMP dependent protein kinase 0.0135 0.076 0.0707
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0086 0.0252 0.0196
Onchocerca volvulus 0.0129 0.0699 0.1104
Echinococcus granulosus serine/threonine protein kinase 0.0138 0.0797 0.0743
Loa Loa (eye worm) hypothetical protein 0.0099 0.0384 0.0399
Brugia malayi Temporarily assigned gene name protein 59 0.0129 0.0697 0.0757
Loa Loa (eye worm) TK/FER protein kinase 0.0104 0.0441 0.0461
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0086 0.0252 0.0196
Trichomonas vaginalis CMGC family protein kinase 0.0129 0.0699 0.1122
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0129 0.0699 0.2852
Echinococcus multilocularis serine:threonine protein kinase 38 0.0154 0.0963 0.1143
Toxoplasma gondii AGC kinase 0.0113 0.0535 0.1931
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0146 0.0874 0.1378
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0113 0.0535 0.0654
Echinococcus granulosus roundabout 2 0.0139 0.0803 0.0749
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0113 0.0535 0.0621
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.008 0.0185 0.0195
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0175 0.1176 0.1262
Echinococcus granulosus tyrosine protein kinase Src42A 0.0147 0.0888 0.0835
Trichomonas vaginalis AGC family protein kinase 0.0113 0.0535 0.0858
Echinococcus granulosus homeodomain interacting protein kinase 3 0.0203 0.1472 0.1422
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0113 0.0535 0.0581
Schistosoma mansoni serine/threonine protein kinase 0.0154 0.096 0.1544
Loa Loa (eye worm) hypothetical protein 0.0098 0.0377 0.0391

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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