Detailed information for compound 69738

Basic information

Technical information
  • TDR Targets ID: 69738
  • Name: 1-(1-hydroxy-2,4,4a,6,7,7a-hexahydrofuro[3,2- d][1,3]oxazin-6-yl)-5-methylpyrimidine-2,4-di one
  • MW: 269.254 | Formula: C11H15N3O5
  • H donors: 2 H acceptors: 3 LogP: -0.87 Rotable bonds: 1
    Rule of 5 violations (Lipinski): 1
  • SMILES: ON1COCC2C1CC(O2)n1cc(C)c(=O)[nH]c1=O
  • InChi: 1S/C11H15N3O5/c1-6-3-13(11(16)12-10(6)15)9-2-7-8(19-9)4-18-5-14(7)17/h3,7-9,17H,2,4-5H2,1H3,(H,12,15,16)
  • InChiKey: XPWHXCAXOARGSM-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 1-(1-hydroxy-2,4,4a,6,7,7a-hexahydrofuro[3,2-d][1,3]oxazin-6-yl)-5-methyl-pyrimidine-2,4-dione
  • 1-(1-hydroxy-2,4,4a,6,7,7a-hexahydrofuro[3,2-d][1,3]oxazin-6-yl)-5-methyl-pyrimidine-2,4-quinone
  • 1-(1-hydroxy-2,4,4a,6,7,7a-hexahydrofuro[4,5-d][1,3]oxazin-6-yl)-5-methylpyrimidine-2,4-dione
  • 1-(1-hydroxy-2,4,4a,6,7,7a-hexahydrofuro[4,5-d][1,3]oxazin-6-yl)-5-methyl-pyrimidine-2,4-dione
  • 1-(1-hydroxy-2,4,4a,6,7,7a-hexahydrofuro[4,5-d][1,3]oxazin-6-yl)-5-methyl-pyrimidine-2,4-quinone
  • NSC651814
  • NCI60_018132

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0059 0.0188 0.0184
Leishmania major GPI-anchor transamidase subunit 8 (GPI8), putative 0.0345 0.1283 0.475
Loa Loa (eye worm) hypothetical protein 0.0023 0.005 0.0088
Schistosoma mansoni voltage-gated potassium channel 0.0011 0.0004 0.0007
Loa Loa (eye worm) hypothetical protein 0.0012 0.0008 0.0014
Loa Loa (eye worm) hypothetical protein 0.0338 0.1258 0.2224
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0022 0.0044 0.0079
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0023 0.005 0.0068
Brugia malayi Cytochrome P450 family protein 0.0014 0.0017 0.0029
Echinococcus granulosus g-protein coupled receptor 0.0338 0.1258 0.1254
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0012 0.0008 0.0014
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0338 0.1258 0.2224
Mycobacterium tuberculosis Possible arylsulfatase AtsA (aryl-sulfate sulphohydrolase) (arylsulphatase) 0.0017 0.0027 0.0123
Loa Loa (eye worm) hypothetical protein 0.0012 0.0008 0.0014
Echinococcus granulosus serotonin receptor 0.0338 0.1258 0.1254
Brugia malayi hypothetical protein 0.0338 0.1258 0.2224
Plasmodium falciparum GPI-anchor transamidase, putative 0.0345 0.1283 1
Leishmania major cytochrome p450-like protein 0.0014 0.0017 0.0019
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0711 0.2687 0.4752
Loa Loa (eye worm) hypothetical protein 0.0338 0.1258 0.2224
Brugia malayi Serotonin/octopamine receptor family protein 7 0.091 0.3447 0.6096
Schistosoma mansoni polycystin 1-related 0.002 0.004 0.007
Onchocerca volvulus 0.0338 0.1258 0.2213
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0088 0.0299 0.0529
Schistosoma mansoni hypothetical protein 0.0013 0.001 0.0018
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.1486 0.5655 1
Trichomonas vaginalis conserved hypothetical protein 0.0056 0.0175 0.029
Schistosoma mansoni serine-type protease inhibitor 0.0106 0.0367 0.0649
Trichomonas vaginalis esterase, putative 0.0038 0.0107 0.0168
Echinococcus multilocularis hyperpolarization activated cyclic 0.0018 0.003 0.0027
Brugia malayi hypothetical protein 0.0338 0.1258 0.2224
Schistosoma mansoni lamin 0.0054 0.0168 0.0297
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0027 0.0028
Plasmodium vivax hypothetical protein, conserved 0.0031 0.0079 0.0617
Schistosoma mansoni nAChR subunit 0.0012 0.0008 0.0014
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0098 0.0324
Schistosoma mansoni neuropeptide receptor 0.0338 0.1258 0.2224
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0059 0.0188 0.0661
Leishmania major cytochrome p450-like protein 0.0014 0.0017 0.0019
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0038 0.0108 0.036
Schistosoma mansoni hypothetical protein 0.0031 0.0079 0.014
Echinococcus granulosus netrin receptor unc 5 0.0015 0.0018 0.0014
Entamoeba histolytica GPI-anchor transamidase, putative 0.0345 0.1283 1
Loa Loa (eye worm) PAN domain-containing protein 0.0017 0.0025 0.0044
Treponema pallidum sodium- and chloride- dependent transporter 0.0234 0.0857 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0108 0.0171
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0012 0.0008 0.0014
Onchocerca volvulus 0.0338 0.1258 0.2213
Loa Loa (eye worm) hypothetical protein 0.0338 0.1258 0.2224
Brugia malayi G-protein coupled receptor 0.0338 0.1258 0.2224
Echinococcus granulosus kelch ECH associated protein 1 like 0.0013 0.001 0.0006
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0027 0.0065 0.024
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0338 0.1258 0.1254
Loa Loa (eye worm) hypothetical protein 0.002 0.004 0.0071
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0108 0.0171
Toxoplasma gondii hypothetical protein 0.004 0.0114 0.0885
Loa Loa (eye worm) hypothetical protein 0.0038 0.0107 0.0189
Loa Loa (eye worm) hypothetical protein 0.0284 0.105 0.1857
Mycobacterium leprae putative cytochrome p450 0.0014 0.0017 0.0058
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0044 0.0058
Loa Loa (eye worm) hypothetical protein 0.0338 0.1258 0.2224
Echinococcus granulosus rhodopsin orphan GPCR 0.0338 0.1258 0.1254
Plasmodium vivax glutathione reductase, putative 0.0094 0.0324 0.2523
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.002 0.0037 0.008
Echinococcus granulosus regulator of G protein signaling 7 0.0022 0.0044 0.004
Brugia malayi AKH receptor 0.0338 0.1258 0.2224
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.004 0.0036
Trichomonas vaginalis conserved hypothetical protein 0.0079 0.0264 0.0446
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0079 0.0264 0.0453
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0018 0.003 0.0236
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.004 0.0114 0.0201
Plasmodium vivax hypothetical protein, conserved 0.004 0.0114 0.0885
Echinococcus granulosus 6 phosphofructokinase 0.0227 0.083 0.0826
Loa Loa (eye worm) hypothetical protein 0.0022 0.0044 0.0079
Brugia malayi cytoplasmic intermediate filament protein 0.0029 0.0072 0.0128
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0038 0.0108 0.0191
Echinococcus granulosus tm gpcr rhodopsin 0.0338 0.1258 0.1254
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0038 0.0107 0.1033
Toxoplasma gondii exonuclease III APE 0.002 0.0037 0.0291
Toxoplasma gondii PAN domain-containing protein 0.0017 0.0025 0.0195
Loa Loa (eye worm) hypothetical protein 0.0338 0.1258 0.2224
Echinococcus multilocularis nAChR subunit 0.0012 0.0008 0.0004
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0338 0.1258 0.1254
Loa Loa (eye worm) hypothetical protein 0.1304 0.4958 0.8768
Brugia malayi intermediate filament protein 0.0054 0.0168 0.0297
Toxoplasma gondii hypothetical protein 0.004 0.0114 0.0885
Echinococcus multilocularis expressed protein 0.0387 0.1445 0.1442
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0012 0.0008 0.0014
Schistosoma mansoni single-minded 0.005 0.0154 0.0272
Schistosoma mansoni neuropeptide receptor 0.0338 0.1258 0.2224
Echinococcus multilocularis neuropeptide receptor A26 0.0338 0.1258 0.1254
Trypanosoma cruzi hypothetical protein, conserved 0.0018 0.003 0.0069
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0013 0.0012 0.0008
Onchocerca volvulus 0.0018 0.003 0.0039
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0012 0.0008 0.0014
Loa Loa (eye worm) doublecortin family protein 0.002 0.004 0.007
Brugia malayi phosphofructokinase 0.0227 0.083 0.1467
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0061 0.0196 0.1529
Echinococcus multilocularis regulator of G protein signaling 3 0.0022 0.0044 0.0041
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0027 0.0028
Onchocerca volvulus 0.0017 0.0025 0.0031
Loa Loa (eye worm) hypothetical protein 0.0338 0.1258 0.2224
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0122 0.0431 0.1566
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0015 0.0019 0.0034
Loa Loa (eye worm) hypothetical protein 0.0017 0.0025 0.0044
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0033 0.0087 0.0282
Echinococcus granulosus neuropeptide FF receptor 2 0.0338 0.1258 0.1254
Onchocerca volvulus 0.0338 0.1258 0.2213
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0018 0.003 0.0054
Echinococcus multilocularis regulator of G protein signaling 7 0.0022 0.0044 0.0041
Schistosoma mansoni hypothetical protein 0.0018 0.003 0.0053
Brugia malayi PXA domain containing protein 0.0022 0.0044 0.0079
Schistosoma mansoni 60S ribosomal protein L21 0.0015 0.0019 0.0034
Brugia malayi Dopamine receptor 0.0338 0.1258 0.2224
Loa Loa (eye worm) hypothetical protein 0.0338 0.1258 0.2224
Loa Loa (eye worm) hypothetical protein 0.0012 0.0008 0.0014
Brugia malayi M-phase phosphoprotein, mpp8 0.0023 0.005 0.0088
Brugia malayi hypothetical protein 0.002 0.004 0.007
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0216 0.0787 0.8938
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0027 0.0028
Echinococcus multilocularis PHD finger protein rhinoceros 0.0031 0.0079 0.0075
Loa Loa (eye worm) G-protein coupled receptor 0.0338 0.1258 0.2224
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.002 0.0037 0.0034
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0077 0.0257 0.0253
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0018 0.003 0.0027
Plasmodium falciparum LCCL domain-containing protein 0.002 0.004 0.0309
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.1138 0.4323 0.4321
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0023 0.005 0.0068
Echinococcus granulosus somatostatin receptor 0.0338 0.1258 0.1254
Loa Loa (eye worm) NNMT/PNMT/TEMT family protein 0.0284 0.105 0.1857
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.002 0.0037 0.0213
Loa Loa (eye worm) TK/ROR protein kinase 0.0018 0.003 0.0053
Loa Loa (eye worm) intermediate filament protein 0.0054 0.0168 0.0297
Loa Loa (eye worm) hypothetical protein 0.0022 0.0044 0.0079
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0038 0.0108 0.0104
Echinococcus multilocularis kelch ECH associated protein 1 0.0013 0.001 0.0006
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0338 0.1258 0.1254
Onchocerca volvulus 0.004 0.0114 0.0187
Echinococcus granulosus tachykinin peptides receptor 99D 0.0437 0.1637 0.1633
Mycobacterium leprae conserved hypothetical protein 0.002 0.004 0.0327
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0018 0.003 0.0027
Loa Loa (eye worm) hypothetical protein 0.0338 0.1258 0.2224
Brugia malayi sulfakinin receptor protein 0.0338 0.1258 0.2224
Loa Loa (eye worm) hypothetical protein 0.0338 0.1258 0.2224
Echinococcus multilocularis sex peptide receptor 0.0338 0.1258 0.1254
Loa Loa (eye worm) hypothetical protein 0.0018 0.003 0.0054
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0027 0.0028
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0018 0.003 0.0054
Loa Loa (eye worm) hypothetical protein 0.002 0.004 0.007
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0022 0.0044 0.0041
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0033 0.0087 0.8153
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0012 0.0008 0.0014
Echinococcus granulosus Regulator of G protein signaling 20 0.0022 0.0044 0.004
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0018 0.003 0.0054
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0038 0.0108 0.0401
Trypanosoma brucei trypanothione reductase 0.0094 0.0324 0.1204
Loa Loa (eye worm) hypothetical protein 0.0023 0.005 0.0088
Loa Loa (eye worm) hypothetical protein 0.0012 0.0008 0.0014
Mycobacterium ulcerans glutaminase 0.0269 0.0992 1
Loa Loa (eye worm) hypothetical protein 0.0338 0.1258 0.2224
Onchocerca volvulus 0.0017 0.0025 0.0031
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0338 0.1258 0.2224
Echinococcus multilocularis neuropeptides capa receptor 0.0399 0.1492 0.1489
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0012 0.0008 0.0004
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.005 0.0068
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0024 0.0054 0.0095
Onchocerca volvulus 0.0017 0.0025 0.0031
Loa Loa (eye worm) hypothetical protein 0.0012 0.0008 0.0014
Brugia malayi hypothetical protein 0.0338 0.1258 0.2224
Brugia malayi hypothetical protein 0.0338 0.1258 0.2224
Loa Loa (eye worm) hypothetical protein 0.004 0.0114 0.0201
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0023 0.005 0.0068
Trichomonas vaginalis chromobox protein, putative 0.0141 0.05 0.0866
Entamoeba histolytica recQ family helicase, putative 0.0023 0.005 0.0105
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0023 0.005 0.0388
Brugia malayi Associated with TFs and helicases family protein 0.0023 0.005 0.0088
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.005 0.0068
Onchocerca volvulus 0.0038 0.0107 0.0175
Giardia lamblia Sgs1 DNA helicase, putative 0.0018 0.003 0.0024
Echinococcus granulosus rhodopsin orphan GPCR 0.0338 0.1258 0.1254
Schistosoma mansoni opsin-like receptor 0.0338 0.1258 0.2224
Plasmodium falciparum thioredoxin reductase 0.0094 0.0324 0.2523
Loa Loa (eye worm) hypothetical protein 0.0012 0.0008 0.0014
Brugia malayi F/Y-rich N-terminus family protein 0.0017 0.0026 0.0045
Loa Loa (eye worm) hypoxia-induced factor 1 0.0155 0.0557 0.0985
Onchocerca volvulus 0.0066 0.0213 0.0364
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0018 0.003 0.0054
Trichomonas vaginalis phosphofructokinase, putative 0.0061 0.0196 0.0327
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0012 0.0008 0.0004
Schistosoma mansoni lipoxygenase 0.0122 0.0428 0.0757
Echinococcus multilocularis chromobox protein 1 0.0141 0.05 0.0497
Onchocerca volvulus 0.0338 0.1258 0.2213
Echinococcus granulosus lysine specific demethylase 5A 0.0037 0.0104 0.01
Toxoplasma gondii PAN/Apple domain-containing protein 0.0017 0.0025 0.0195
Entamoeba histolytica hypothetical protein 0.0023 0.005 0.0099
Mycobacterium ulcerans aldehyde dehydrogenase 0.0122 0.0431 0.4246
Echinococcus granulosus histone lysine methyltransferase setb 0.0181 0.0657 0.0653
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0033 0.0087 0.0282
Brugia malayi hypothetical protein 0.0338 0.1258 0.2224
Entamoeba histolytica hypothetical protein 0.0023 0.005 0.0099
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0033 0.0087 0.0154
Plasmodium falciparum transporter, putative 0.004 0.0114 0.0885
Schistosoma mansoni serine-type protease inhibitor 0.0106 0.0367 0.0649
Loa Loa (eye worm) hypothetical protein 0.0338 0.1258 0.2224
Schistosoma mansoni regulator of G protein signaling 0.0022 0.0044 0.0079
Schistosoma mansoni regulator of G protein signaling 0.0022 0.0044 0.0079
Loa Loa (eye worm) hypothetical protein 0.0026 0.0061 0.0108
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.004 0.0114 0.011
Echinococcus multilocularis geminin 0.0167 0.06 0.0597
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0033 0.0087 0.0282
Mycobacterium tuberculosis Probable hydrolase 0.0038 0.0107 0.1033
Brugia malayi Protein kinase domain containing protein 0.0015 0.0019 0.0033
Toxoplasma gondii microneme protein MIC17A 0.0017 0.0025 0.0195
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0012 0.0008 0.0014
Echinococcus multilocularis axis inhibition protein axin 0.0022 0.0044 0.0041
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0017 0.0026 0.0045
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.002 0.0037 0.0096
Leishmania major protein kinase, putative 0.0013 0.0012 0.0002
Brugia malayi Bromodomain containing protein 0.0031 0.0079 0.014
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0338 0.1258 0.2224
Trichomonas vaginalis flap endonuclease-1, putative 0.0027 0.0065 0.0094
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0018 0.003 0.0236
Echinococcus granulosus glycine receptor subunit alpha 1 0.0012 0.0008 0.0004
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0027 0.0028
Loa Loa (eye worm) peptidase C13 family protein 0.1486 0.5655 1
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0031 0.0079 0.014
Brugia malayi ORL1-like opioid receptor 0.0338 0.1258 0.2224
Schistosoma mansoni ap endonuclease 0.002 0.0037 0.0066
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0018 0.003 0.0027
Brugia malayi Heterochromatin protein 1 0.0141 0.05 0.0885
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0018 0.003 0.0026
Echinococcus granulosus neuropeptide Y receptor 0.0338 0.1258 0.1254
Loa Loa (eye worm) hypothetical protein 0.0338 0.1258 0.2224
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0345 0.1283 0.2252
Leishmania major trypanothione reductase 0.0094 0.0324 0.1166
Plasmodium falciparum glutathione reductase 0.0094 0.0324 0.2523
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0338 0.1258 0.2224
Echinococcus granulosus geminin 0.0167 0.06 0.0596
Brugia malayi putative neuropeptide receptor NPR1 0.0338 0.1258 0.2224
Loa Loa (eye worm) hypothetical protein 0.0234 0.0857 0.1515
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0338 0.1258 0.2224
Brugia malayi Dopamine receptor protein 1 0.0765 0.2892 0.5113
Trichomonas vaginalis phosphofructokinase, putative 0.0061 0.0196 0.0327
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0023 0.005 0.0388
Brugia malayi latrophilin 2 splice variant baaae 0.0019 0.0034 0.006
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0054 0.0168 0.0297
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0018 0.003 0.0026
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0338 0.1258 0.2224
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0012 0.0008 0.0014
Entamoeba histolytica hypothetical protein 0.0022 0.0044 0.0056
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.002 0.0037 0.0096
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0338 0.1258 0.1254
Schistosoma mansoni lamin 0.0054 0.0168 0.0297
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0122 0.0428 0.0424
Brugia malayi GnHR receptor homolog 0.0338 0.1258 0.2224
Schistosoma mansoni intermediate filament proteins 0.0054 0.0168 0.0297
Echinococcus multilocularis regulator of G protein signaling 3 0.0022 0.0044 0.0041
Leishmania major ATP-dependent phosphofructokinase 0.0227 0.083 0.3057
Echinococcus multilocularis fmrfamide receptor 0.0338 0.1258 0.1254
Brugia malayi beta-lactamase family protein 0.0038 0.0107 0.0189
Onchocerca volvulus 0.0066 0.0213 0.0364
Brugia malayi Uncoordinated protein 44 0.0015 0.0018 0.0033
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0076 0.0253 0.0249
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0044 0.0058
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0107 0.0355
Plasmodium falciparum thioredoxin reductase 0.0033 0.0087 0.0679
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0023 0.005 0.0388
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0038 0.0108 0.0104
Loa Loa (eye worm) hypothetical protein 0.0588 0.2215 0.3918
Brugia malayi Cation transporter family protein 0.0012 0.0008 0.0014
Giardia lamblia Flap structure-specific endonuclease 0.0027 0.0065 0.0297
Toxoplasma gondii endonuclease IV APN 0.0078 0.026 0.2025
Echinococcus granulosus ubiquitin specific protease 41 0.0038 0.0108 0.0104
Brugia malayi Protein cec-1. 0.0023 0.005 0.0088
Mycobacterium ulcerans aldehyde dehydrogenase 0.0122 0.0431 0.4246
Echinococcus multilocularis tissue type plasminogen activator 0.0018 0.003 0.0026
Brugia malayi hypothetical protein 0.0338 0.1258 0.2224
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0025 0.0056 0.01
Schistosoma mansoni biogenic amine (5HT) receptor 0.1066 0.4044 0.7151
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.005 0.0068
Toxoplasma gondii NADPH-glutathione reductase 0.0033 0.0087 0.0679
Giardia lamblia GPI-anchor transamidase, putative 0.0345 0.1283 1
Onchocerca volvulus 0.0023 0.005 0.0074
Mycobacterium tuberculosis Conserved hypothetical protein 0.002 0.004 0.0268
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0012 0.0008 0.0014
Mycobacterium ulcerans aldehyde dehydrogenase 0.0122 0.0431 0.4246
Loa Loa (eye worm) hypothetical protein 0.0338 0.1258 0.2224
Schistosoma mansoni hypothetical protein 0.0019 0.0034 0.006
Loa Loa (eye worm) hypothetical protein 0.0067 0.022 0.0389
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0033 0.0087 0.0282
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.1265 0.4809 0.8503
Onchocerca volvulus 0.0017 0.0025 0.0031
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0023 0.005 0.0046
Brugia malayi Flap endonuclease-1 0.0027 0.0065 0.0114
Echinococcus granulosus sex peptide receptor 0.0338 0.1258 0.1254
Brugia malayi Cation transporter family protein 0.0012 0.0008 0.0014
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0023 0.005 0.0388
Echinococcus granulosus regulator of G protein signaling 7 0.0022 0.0044 0.004
Schistosoma mansoni rab6-interacting 0.002 0.004 0.007
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0061 0.0196 0.1344
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0012 0.0008 0.0014
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0012 0.0008 0.0004
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0078 0.026 0.2788
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0338 0.1258 0.1254
Plasmodium vivax flap endonuclease 1, putative 0.0027 0.0065 0.0504
Echinococcus multilocularis lamin 0.0054 0.0168 0.0164
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0338 0.1258 0.1254
Loa Loa (eye worm) hypothetical protein 0.091 0.3447 0.6096
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.004 0.0114 0.0885
Brugia malayi Hypothetical tyrosinase-like protein C02C2.1 in chromosome III 0.0066 0.0213 0.0377
Schistosoma mansoni lipoxygenase 0.0085 0.0288 0.0509
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0027 0.0065 0.0198
Echinococcus multilocularis dro:myosuppressin receptor 0.0338 0.1258 0.1254
Loa Loa (eye worm) hypothetical protein 0.0022 0.0044 0.0079
Loa Loa (eye worm) hypothetical protein 0.0012 0.0008 0.0014
Echinococcus multilocularis serotonin receptor 0.1304 0.4958 0.4956
Trichomonas vaginalis conserved hypothetical protein 0.0079 0.0264 0.0446
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0028 0.0071 0.0125
Trichomonas vaginalis set domain proteins, putative 0.144 0.5478 0.9687
Loa Loa (eye worm) hypothetical protein 0.0338 0.1258 0.2224
Schistosoma mansoni hypothetical protein 0.0338 0.1258 0.2224
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0027 0.0028
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0027 0.0028
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.024 0.088 0.9897
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0012 0.0008 0.0014
Mycobacterium ulcerans hypothetical protein 0.002 0.004 0.024
Echinococcus multilocularis neuropeptide receptor 0.0338 0.1258 0.1254
Schistosoma mansoni biogenic amine receptor 0.0338 0.1258 0.2224
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.024 0.088 1
Echinococcus granulosus chromobox protein 2 0.0023 0.005 0.0046
Echinococcus multilocularis jumonji domain containing protein 0.0043 0.0125 0.0121
Schistosoma mansoni histamine h1 receptor 0.0338 0.1258 0.2224
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0014 0.0017 0.0019
Brugia malayi Cation transporter family protein 0.0012 0.0008 0.0014
Echinococcus multilocularis glycine receptor subunit beta 0.0012 0.0008 0.0004
Onchocerca volvulus 0.0066 0.0213 0.0364
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0022 0.0044 0.0079
Schistosoma mansoni growth hormone secretagogue receptor 0.0338 0.1258 0.2224
Onchocerca volvulus 0.0338 0.1258 0.2213
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0012 0.0008 0.0014
Loa Loa (eye worm) hypothetical protein 0.0017 0.0025 0.0044
Loa Loa (eye worm) hypothetical protein 0.0338 0.1258 0.2224
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0012 0.0008 0.0014
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0023 0.005 0.0088
Loa Loa (eye worm) hypothetical protein 0.0066 0.0213 0.0377
Loa Loa (eye worm) hypothetical protein 0.0023 0.005 0.0088
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.091 0.3447 0.6096
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0033 0.0087 0.3041
Brugia malayi Intermediate filament tail domain containing protein 0.0054 0.0168 0.0297
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0012 0.0008 0.0004
Schistosoma mansoni z-protein (S1r protein) 0.0022 0.0044 0.0079
Echinococcus granulosus rhodopsin orphan GPCR 0.0338 0.1258 0.1254
Toxoplasma gondii PAN domain-containing protein 0.0017 0.0025 0.0195
Echinococcus granulosus bloom syndrome protein 0.0043 0.0128 0.0124
Schistosoma mansoni regulator of G protein signaling 0.0022 0.0044 0.0079
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0077 0.0257 0.0253
Echinococcus multilocularis g protein coupled receptor 0.0338 0.1258 0.1254
Loa Loa (eye worm) hypothetical protein 0.0023 0.005 0.0088
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0012 0.0008 0.0004
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0018 0.003 0.0026
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0181 0.0657 0.1162
Trichomonas vaginalis conserved hypothetical protein 0.0056 0.0175 0.029
Onchocerca volvulus 0.0338 0.1258 0.2213
Entamoeba histolytica hypothetical protein 0.0023 0.005 0.0099
Loa Loa (eye worm) hypothetical protein 0.0338 0.1258 0.2224
Echinococcus multilocularis RUN 0.002 0.004 0.0036
Echinococcus granulosus orexin receptor type 2 0.0338 0.1258 0.1254
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0181 0.0657 0.0653
Loa Loa (eye worm) hypothetical protein 0.0017 0.0025 0.0044
Toxoplasma gondii microneme protein, putative 0.0017 0.0025 0.0195
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0033 0.0087 0.0282
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0061 0.0196 0.0327
Onchocerca volvulus 0.0017 0.0025 0.0031
Toxoplasma gondii peptidase c13 family protein 0.0345 0.1283 1
Trypanosoma brucei hypothetical protein, conserved 0.0038 0.0107 0.0397
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0216 0.0787 0.884
Onchocerca volvulus 0.0338 0.1258 0.2213
Brugia malayi G-protein coupled receptor 0.0338 0.1258 0.2224
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0038 0.0108 0.0566
Echinococcus granulosus tm gpcr rhodopsin 0.1138 0.4323 0.432
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.01 0.0346 0.0342
Brugia malayi Sodium:neurotransmitter symporter family protein 0.004 0.0114 0.0201
Toxoplasma gondii ABC1 family protein 0.0038 0.0107 0.0832
Plasmodium vivax amine transporter, putative 0.004 0.0114 0.0885
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0085 0.0286 0.0494
Loa Loa (eye worm) CHromoDomain protein family member 0.0023 0.005 0.0088
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0012 0.0008 0.0014
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0227 0.083 0.9323
Leishmania major cytochrome p450-like protein 0.0023 0.0051 0.0148
Mycobacterium ulcerans beta-lactamase 0.0038 0.0107 0.0924
Schistosoma mansoni 6-phosphofructokinase 0.0227 0.083 0.1467
Loa Loa (eye worm) G-protein coupled receptor 0.0338 0.1258 0.2224
Schistosoma mansoni netrin receptor unc5 0.0015 0.0018 0.0033
Loa Loa (eye worm) hypothetical protein 0.0338 0.1258 0.2224
Loa Loa (eye worm) hypothetical protein 0.0038 0.0107 0.0189
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.1486 0.5655 1
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0122 0.0428 0.0425
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0038 0.0107 0.1033
Echinococcus granulosus 7tm_1 domain containing protein 0.0338 0.1258 0.1254
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.002 0.0037 0.0139
Brugia malayi hypothetical protein 0.0338 0.1258 0.2224
Echinococcus granulosus neuropeptide s receptor 0.0338 0.1258 0.1254
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.002 0.0037 0.0238
Loa Loa (eye worm) neuropeptide F receptor 0.0338 0.1258 0.2224
Echinococcus multilocularis neuropeptide s receptor 0.0338 0.1258 0.1254
Plasmodium vivax multidomain scavenger receptor, putative 0.002 0.004 0.0309
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0036 0.0098 0.0838
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0338 0.1258 0.2224
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0094 0.0324 0.3521
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0098 0.0154
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0338 0.1258 0.2224
Schistosoma mansoni myosin xvIII 0.0338 0.1258 0.2224
Loa Loa (eye worm) tyrosinase 1 0.0066 0.0213 0.0377
Onchocerca volvulus Legumain homolog 0.1486 0.5655 1
Echinococcus multilocularis biogenic amine (5HT) receptor 0.1066 0.4044 0.4042
Brugia malayi hypothetical protein 0.0338 0.1258 0.2224
Echinococcus granulosus Polycystic kidney disease protein 0.002 0.004 0.0035
Plasmodium vivax hypothetical protein, conserved 0.0023 0.005 0.0388
Brugia malayi Regulator of G protein signaling domain containing protein 0.0022 0.0044 0.0079
Loa Loa (eye worm) cytochrome P450 family protein 0.0014 0.0017 0.0029
Schistosoma mansoni voltage-gated potassium channel 0.0025 0.0056 0.01
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0122 0.0431 0.4747
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.004 0.0114 0.0201
Echinococcus multilocularis peregrin 0.0031 0.0079 0.0075
Loa Loa (eye worm) RecQ helicase 0.0043 0.0128 0.0226
Mycobacterium ulcerans 6-phosphofructokinase 0.0227 0.083 0.8339
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0338 0.1258 0.1254
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0037 0.0291
Echinococcus multilocularis rhodopsin orphan GPCR 0.0338 0.1258 0.1254
Loa Loa (eye worm) hypothetical protein 0.0012 0.0008 0.0014
Trichomonas vaginalis phosphofructokinase, putative 0.0227 0.083 0.1449
Onchocerca volvulus 0.0338 0.1258 0.2213
Echinococcus granulosus GPI anchor transamidase 0.0345 0.1283 0.1279
Plasmodium vivax heterochromatin protein 1, putative 0.0023 0.005 0.0388
Echinococcus multilocularis rhodopsin orphan GPCR 0.0338 0.1258 0.1254
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0033 0.0087 0.0808
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0012 0.0008 0.0014
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0018 0.003 0.0054
Brugia malayi PAN domain containing protein 0.0017 0.0025 0.0044
Brugia malayi GPI-anchor transamidase 0.0345 0.1283 0.2268
Brugia malayi hypothetical protein 0.0338 0.1258 0.2224
Echinococcus multilocularis transfer RNA-Lys 0.0037 0.0104 0.01
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0345 0.1283 0.2252
Loa Loa (eye worm) hypothetical protein 0.0765 0.2892 0.5113
Schistosoma mansoni neuropeptide receptor 0.0338 0.1258 0.2224
Loa Loa (eye worm) hypothetical protein 0.0011 0.0004 0.0007
Loa Loa (eye worm) PAN domain-containing protein 0.0017 0.0025 0.0044
Onchocerca volvulus 0.0017 0.0025 0.0031
Loa Loa (eye worm) hypothetical protein 0.0038 0.0107 0.0189
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0038 0.0108 0.084
Echinococcus granulosus inositol monophosphatase 1 0.0036 0.0098 0.0094
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0059 0.0188 0.1971
Schistosoma mansoni hypothetical protein 0.1141 0.4334 0.7664
Echinococcus multilocularis Kelch repeat type 1 0.0013 0.001 0.0006
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0027 0.0028
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0025 0.0056 0.0053
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0044 0.0058
Entamoeba histolytica hypothetical protein 0.0022 0.0044 0.0056
Loa Loa (eye worm) hypothetical protein 0.0338 0.1258 0.2224
Echinococcus granulosus axis inhibition protein axin 0.0022 0.0044 0.004
Loa Loa (eye worm) hypothetical protein 0.0338 0.1258 0.2224
Echinococcus multilocularis Chromobox protein 3 0.0023 0.005 0.0046
Mycobacterium ulcerans arylsulfatase AtsD 0.0017 0.0027 0.011
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.262 1 1
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0227 0.083 0.3057
Loa Loa (eye worm) hypothetical protein 0.004 0.0114 0.0201
Loa Loa (eye worm) beta-lactamase 0.0038 0.0107 0.0189
Loa Loa (eye worm) hypothetical protein 0.0012 0.0008 0.0014
Loa Loa (eye worm) hypothetical protein 0.0023 0.005 0.0089
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0036 0.0098 0.0766
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.005 0.0068
Schistosoma mansoni aldehyde dehydrogenase 0.0122 0.0431 0.0761
Echinococcus multilocularis rhodopsin orphan GPCR 0.0338 0.1258 0.1254
Echinococcus granulosus glycine receptor subunit alpha 1 0.0012 0.0008 0.0004
Loa Loa (eye worm) hypothetical protein 0.0012 0.0008 0.0014
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0338 0.1258 0.2224
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0033 0.0087 0.0154
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0338 0.1258 0.1254
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0023 0.005 0.0145
Echinococcus multilocularis flap endonuclease 1 0.0027 0.0065 0.0061
Entamoeba histolytica phosphofructokinase, putative 0.0227 0.083 0.6361
Loa Loa (eye worm) hypothetical protein 0.0017 0.0025 0.0044
Schistosoma mansoni jumonji domain containing protein 0.008 0.0267 0.0473
Brugia malayi RE15519p 0.0338 0.1258 0.2224
Echinococcus multilocularis allatostatin A receptor 0.0338 0.1258 0.1254
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0338 0.1258 0.2224
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.004 0.0114 0.0109
Brugia malayi Serotonin receptor 0.0783 0.296 0.5235
Schistosoma mansoni opsin-like receptor 0.0338 0.1258 0.2224
Loa Loa (eye worm) hypothetical protein 0.0012 0.0008 0.0014
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.01 0.0346 0.0343
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0022 0.0044 0.0058
Brugia malayi 6-phosphofructokinase 0.0227 0.083 0.1467
Mycobacterium tuberculosis Probable dehydrogenase 0.0216 0.0787 0.884
Trichomonas vaginalis chromobox protein, putative 0.0023 0.005 0.0068
Loa Loa (eye worm) hypothetical protein 0.0012 0.0008 0.0014
Trypanosoma cruzi cytochrome P450, putative 0.0023 0.0051 0.0148
Schistosoma mansoni nAChR subunit 0.0012 0.0008 0.0014
Brugia malayi Cytochrome P450 family protein 0.0014 0.0017 0.0029
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0061 0.0196 0.1529
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0181 0.0657 0.0653
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0122 0.0431 0.0427
Echinococcus multilocularis regulator of G protein signaling 7 0.0022 0.0044 0.0041
Toxoplasma gondii PAN domain-containing protein 0.009 0.0305 0.2375
Loa Loa (eye worm) hypothetical protein 0.0338 0.1258 0.2224
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0338 0.1258 0.1254
Schistosoma mansoni opsin-like receptor 0.0338 0.1258 0.2224
Loa Loa (eye worm) hypothetical protein 0.0012 0.0008 0.0014
Echinococcus granulosus 7TM GPCR rhodopsin 0.0338 0.1258 0.1254
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0023 0.005 0.0068
Schistosoma mansoni rab6-interacting 0.002 0.004 0.007
Brugia malayi PAS domain containing protein 0.005 0.0154 0.0272
Trichomonas vaginalis glutathione reductase, putative 0.0033 0.0087 0.0134
Brugia malayi PAN domain containing protein 0.0017 0.0025 0.0044
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0338 0.1258 0.2224
Schistosoma mansoni hypothetical protein 0.0338 0.1258 0.2224
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0077 0.0257 0.0455
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0033 0.0087 0.0282
Loa Loa (eye worm) hypothetical protein 0.0012 0.0008 0.0014
Toxoplasma gondii cytochrome p450 superfamily protein 0.0014 0.0017 0.0129
Brugia malayi ShTK domain containing protein 0.0066 0.0213 0.0377
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0012 0.0008 0.0014
Plasmodium vivax hypothetical protein, conserved 0.0023 0.005 0.0388
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0022 0.0044 0.004
Loa Loa (eye worm) hypothetical protein 0.0038 0.0107 0.0189
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.005 0.0068
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.002 0.0037 0.0096
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0023 0.005 0.0068
Loa Loa (eye worm) flap endonuclease-1 0.0027 0.0065 0.0114
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0013 0.0012 0.0002
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0033 0.0087 0.0282
Mycobacterium tuberculosis Probable esterase LipL 0.0038 0.0107 0.1033
Loa Loa (eye worm) hypothetical protein 0.0078 0.026 0.0459
Plasmodium vivax SET domain protein, putative 0.0181 0.0657 0.5121
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0027 0.0028
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.002 0.004 0.0071
Echinococcus granulosus hyperpolarization activated cyclic 0.0018 0.003 0.0026
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0012 0.0008 0.0004
Echinococcus multilocularis rhodopsin orphan GPCR 0.0338 0.1258 0.1254
Echinococcus multilocularis G-protein coupled receptor, putative 0.0338 0.1258 0.1254
Trichomonas vaginalis glutaminase, putative 0.0269 0.0992 0.1736
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0033 0.0087 0.0324
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0022 0.0044 0.0079
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0059 0.0188 0.1763
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0061 0.0196 0.7436
Schistosoma mansoni voltage-gated potassium channel 0.0084 0.0283 0.05
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0018 0.003 0.0054
Loa Loa (eye worm) hypothetical protein 0.0023 0.005 0.0088
Onchocerca volvulus 0.0017 0.0025 0.0031
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0338 0.1258 0.2224
Loa Loa (eye worm) hypothetical protein 0.0025 0.0056 0.01
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0023 0.005 0.0068
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0012 0.0008 0.0004
Onchocerca volvulus 0.0054 0.0168 0.0284
Mycobacterium tuberculosis Conserved protein 0.0038 0.0107 0.1033
Echinococcus multilocularis kelch ECH associated protein 1 0.0013 0.001 0.0006
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.004 0.0114 0.0885
Onchocerca volvulus 0.004 0.0114 0.0187
Loa Loa (eye worm) hypothetical protein 0.002 0.004 0.007
Loa Loa (eye worm) hypothetical protein 0.004 0.0114 0.0201
Loa Loa (eye worm) hypothetical protein 0.0338 0.1258 0.2224
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0107 0.0168
Loa Loa (eye worm) ACC-1 protein 0.0012 0.0008 0.0014
Echinococcus granulosus microtubule associated protein 2 0.1438 0.5472 0.547
Trichomonas vaginalis DNA helicase recq1, putative 0.0043 0.0128 0.0206
Echinococcus granulosus peptide allatostatin:somatostatin 0.0338 0.1258 0.1254
Loa Loa (eye worm) TYRA-2 protein 0.0338 0.1258 0.2224
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0023 0.005 0.0099
Loa Loa (eye worm) 6-phosphofructokinase 0.0227 0.083 0.1467
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0023 0.005 0.0068
Echinococcus multilocularis lysine specific demethylase 5A 0.0037 0.0104 0.01
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0029 0.0073 0.0567
Echinococcus granulosus regulator of G protein signaling 3 0.0022 0.0044 0.004
Schistosoma mansoni tyrosinase precursor 0.0066 0.0213 0.0377
Loa Loa (eye worm) hypothetical protein 0.0053 0.0163 0.0288
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0227 0.083 0.3087
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.004 0.0114 0.0201
Echinococcus granulosus sodium and chloride dependent glycine 0.004 0.0114 0.0109
Loa Loa (eye worm) glutaminase 2 0.0269 0.0992 0.1753
Plasmodium vivax 6-phosphofructokinase, putative 0.0061 0.0196 0.1529
Loa Loa (eye worm) hypothetical protein 0.0066 0.0213 0.0377
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.005 0.0068
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0098 0.0324
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0029 0.0074 0.0578
Trichomonas vaginalis DNA helicase recq, putative 0.0023 0.005 0.0069
Loa Loa (eye worm) ShTK domain-containing protein 0.0066 0.0213 0.0377
Loa Loa (eye worm) glutathione reductase 0.0094 0.0324 0.0572
Brugia malayi chromobox protein homolog 3 0.0079 0.0264 0.0466
Entamoeba histolytica phosphofructokinase, putative 0.0227 0.083 0.6361
Loa Loa (eye worm) PHD-finger family protein 0.0031 0.0079 0.014
Mycobacterium ulcerans arylsulfatase, AslA 0.0017 0.0027 0.011
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.004 0.0114 0.0201
Brugia malayi Dopamine receptor protein 2 0.0338 0.1258 0.2224
Brugia malayi Pre-SET motif family protein 0.0181 0.0657 0.1162
Schistosoma mansoni hypothetical protein 0.0338 0.1258 0.2224
Schistosoma mansoni amine GPCR 0.0338 0.1258 0.2224
Echinococcus multilocularis ubiquitin specific protease 41 0.0038 0.0108 0.0104
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0338 0.1258 0.2224
Loa Loa (eye worm) hypothetical protein 0.0234 0.0857 0.1515
Loa Loa (eye worm) hypothetical protein 0.0053 0.0164 0.0291
Toxoplasma gondii 6-phosphofructokinase 0.0061 0.0196 0.1529
Leishmania major C-8 sterol isomerase-like protein 0.0711 0.2687 1
Schistosoma mansoni serine/threonine protein kinase 0.0028 0.0071 0.0125
Echinococcus granulosus g protein coupled receptor 0.0338 0.1258 0.1254
Loa Loa (eye worm) ShTK domain-containing protein 0.0066 0.0213 0.0377
Schistosoma mansoni serine/threonine protein kinase 0.0028 0.0071 0.0125
Echinococcus multilocularis sodium and chloride dependent glycine 0.004 0.0114 0.011
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0033 0.0087 0.0282
Loa Loa (eye worm) hypothetical protein 0.004 0.0114 0.0201
Schistosoma mansoni loxhd1 0.002 0.004 0.007
Echinococcus granulosus neuropeptide receptor 0.0338 0.1258 0.1254
Loa Loa (eye worm) jmjC domain-containing protein 0.0063 0.0204 0.0361
Schistosoma mansoni jumonji/arid domain-containing protein 0.0037 0.0104 0.0184
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0061 0.0196 0.1274
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0012 0.0008 0.0004
Mycobacterium tuberculosis Possible arylsulfatase AtsD (aryl-sulfate sulphohydrolase) (arylsulphatase) 0.0017 0.0027 0.0123
Loa Loa (eye worm) hypothetical protein 0.0338 0.1258 0.2224
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0038 0.0107 0.0189
Schistosoma mansoni hypothetical protein 0.0338 0.1258 0.2224
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0018 0.003 0.0054
Echinococcus granulosus alpha 1A adrenergic receptor 0.0338 0.1258 0.1254
Plasmodium falciparum heterochromatin protein 1 0.0023 0.005 0.0388
Loa Loa (eye worm) helicase 0.0023 0.005 0.0088
Echinococcus granulosus beta LACTamase domain containing family member 0.0038 0.0107 0.0103
Loa Loa (eye worm) hypothetical protein 0.0019 0.0034 0.006
Loa Loa (eye worm) hypothetical protein 0.0079 0.0264 0.0466
Echinococcus multilocularis beta LACTamase domain containing family member 0.0038 0.0107 0.0103
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0014 0.0017 0.0062
Brugia malayi Protein kinase domain containing protein 0.0018 0.003 0.0053
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0013 0.0012 0.0002
Onchocerca volvulus 0.0338 0.1258 0.2213
Echinococcus granulosus death domain containing protein 0.0015 0.0018 0.0014
Brugia malayi Melatonin receptor type 1A 0.0338 0.1258 0.2224
Trichomonas vaginalis chromobox protein, putative 0.0141 0.05 0.0866
Onchocerca volvulus 0.002 0.004 0.0056
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0023 0.005 0.0188
Brugia malayi Cytochrome P450 family protein 0.0023 0.0051 0.009
Schistosoma mansoni chromobox protein 0.0023 0.005 0.0088
Schistosoma mansoni hemoglobinase (C13 family) 0.1486 0.5655 1
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0033 0.0087 0.0679
Toxoplasma gondii thioredoxin reductase 0.0094 0.0324 0.2523
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0023 0.005 0.0088
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0024 0.0054 0.0095
Brugia malayi Calcitonin receptor-like protein seb-1 0.0028 0.0067 0.0119
Onchocerca volvulus 0.144 0.5479 0.9688
Schistosoma mansoni voltage-gated potassium channel 0.0011 0.0004 0.0007
Loa Loa (eye worm) hypothetical protein 0.0031 0.0079 0.014
Schistosoma mansoni hypothetical protein 0.0167 0.06 0.1061
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0338 0.1258 0.2224
Schistosoma mansoni nAChR subunit 0.0012 0.0008 0.0014
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0018 0.003 0.0054
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0059 0.0188 0.0185
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0027 0.0065 0.0198
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0023 0.005 0.0099
Echinococcus multilocularis rhodopsin orphan GPCR 0.0338 0.1258 0.1254
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0088 0.0299 0.0295
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0061 0.0196 0.1937
Brugia malayi hypothetical protein 0.0338 0.1258 0.2224
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0027 0.0028
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.1486 0.5655 1
Brugia malayi G protein-coupled receptor F59B2.13 0.0338 0.1258 0.2224
Loa Loa (eye worm) hypothetical protein 0.0338 0.1258 0.2224
Toxoplasma gondii PAN domain-containing protein 0.0017 0.0025 0.0195
Loa Loa (eye worm) hypothetical protein 0.0711 0.2687 0.4752
Schistosoma mansoni nAChR subunit 0.0012 0.0008 0.0014
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0012 0.0008 0.0004
Echinococcus granulosus voltage gated potassium channel 0.0025 0.0056 0.0052
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0078 0.026 0.2025
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0033 0.0087 0.0679
Brugia malayi hypothetical protein 0.0017 0.0027 0.0048
Loa Loa (eye worm) heterochromatin protein 1 0.0141 0.05 0.0885
Trichomonas vaginalis hypothetical protein 0.0023 0.005 0.0068
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0033 0.0087 0.0282
Loa Loa (eye worm) hypothetical protein 0.0345 0.1283 0.2268
Echinococcus granulosus aryl hydrocarbon receptor 0.0013 0.0012 0.0007
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0023 0.005 0.0088
Schistosoma mansoni voltage-gated potassium channel 0.0018 0.003 0.0054
Loa Loa (eye worm) hypothetical protein 0.0338 0.1258 0.2224
Mycobacterium ulcerans sulfatase 0.0017 0.0027 0.011
Brugia malayi SET domain containing protein 0.003 0.0075 0.0133
Schistosoma mansoni jumonji/arid domain-containing protein 0.0037 0.0104 0.0184
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0345 0.1283 0.2252
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0012 0.0008 0.0004
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0033 0.0087 0.8153
Brugia malayi Bloom's syndrome protein homolog 0.0043 0.0128 0.0226
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0338 0.1258 0.2224
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0033 0.0087 0.0083
Schistosoma mansoni microtubule-associated protein tau 0.1438 0.5472 0.9676
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0044 0.0058
Loa Loa (eye worm) hypothetical protein 0.0338 0.1258 0.2224
Schistosoma mansoni nAChR subunit 0.0012 0.0008 0.0014
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0029 0.0072 0.0128
Loa Loa (eye worm) norepinephrine transporter 0.0234 0.0857 0.1515
Echinococcus granulosus uncharacterized sodium dependent transporter 0.004 0.0114 0.0109
Echinococcus granulosus neuropeptides capa receptor 0.0399 0.1492 0.1488
Loa Loa (eye worm) hypothetical protein 0.0017 0.0027 0.0048
Brugia malayi PXA domain containing protein 0.0022 0.0044 0.0079
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0069 0.0225 0.0379
Echinococcus multilocularis netrin receptor unc 5 0.0015 0.0018 0.0015
Mycobacterium ulcerans esterase/lipase LipP 0.0038 0.0107 0.0924
Loa Loa (eye worm) hypothetical protein 0.0338 0.1258 0.2224
Brugia malayi neuropeptide F receptor 0.0338 0.1258 0.2224
Echinococcus multilocularis regulator of G protein signaling 0.0022 0.0044 0.0041
Loa Loa (eye worm) hypothetical protein 0.0364 0.1355 0.2396
Schistosoma mansoni adenoreceptor 0.0338 0.1258 0.2224
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0055 0.0173 0.0306
Echinococcus granulosus intermediate filament protein 0.0054 0.0168 0.0164
Plasmodium falciparum glutathione reductase 0.0033 0.0087 0.0679
Trichomonas vaginalis mercuric reductase, putative 0.0033 0.0087 0.0134
Leishmania major hypothetical protein, conserved 0.0038 0.0107 0.0355
Toxoplasma gondii subtilisin SUB12 0.0017 0.0025 0.0195
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0023 0.005 0.0099
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0023 0.005 0.0068
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.1486 0.5655 1
Trichomonas vaginalis phosphofructokinase, putative 0.0061 0.0196 0.0327
Loa Loa (eye worm) hypothetical protein 0.0181 0.0657 0.1162
Echinococcus multilocularis musashi 0.0054 0.0168 0.0164
Loa Loa (eye worm) hypothetical protein 0.0338 0.1258 0.2224
Schistosoma mansoni glutaminase 0.0269 0.0992 0.1753
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0027 0.0028
Loa Loa (eye worm) hypothetical protein 0.0012 0.0008 0.0014
Brugia malayi Tachykinin-like peptides receptor 99D 0.0338 0.1258 0.2224
Trichomonas vaginalis chromobox protein, putative 0.0023 0.005 0.0068
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0216 0.0787 0.884
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0023 0.005 0.0388
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0012 0.0008 0.0014
Echinococcus granulosus fmrfamide receptor 0.0338 0.1258 0.1254
Brugia malayi hypothetical protein 0.002 0.004 0.007
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0033 0.0087 0.0324
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0012 0.0008 0.0014
Echinococcus granulosus nuclear factor of activated T cells 5 0.0076 0.0253 0.0249
Brugia malayi Kringle domain containing protein 0.0018 0.003 0.0053
Echinococcus multilocularis sodium and chloride dependent glycine 0.004 0.0114 0.011
Loa Loa (eye worm) hypothetical protein 0.0017 0.0025 0.0044
Schistosoma mansoni neuropeptide F-like receptor 0.0338 0.1258 0.2224
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0797 0.3017 0.5335
Echinococcus granulosus hyperpolarization activated cyclic 0.0018 0.003 0.0026
Loa Loa (eye worm) cytochrome P450 family protein 0.0023 0.0051 0.009
Trichomonas vaginalis phosphofructokinase, putative 0.0061 0.0196 0.0327
Echinococcus granulosus lamin dm0 0.0054 0.0168 0.0164
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0061 0.0196 0.7436
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0437 0.1637 0.1634
Echinococcus granulosus sodium and chloride dependent glycine 0.004 0.0114 0.0109
Brugia malayi Inositol-1 0.0036 0.0098 0.0174
Loa Loa (eye worm) cytochrome P450 family protein 0.0023 0.0051 0.009
Schistosoma mansoni flap endonuclease-1 0.0024 0.0055 0.0097
Schistosoma mansoni glycosylphosphatidylinositol:protein transamidase (C13 family) 0.0345 0.1283 0.2268
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0069 0.0225 0.0379
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0338 0.1258 0.2224
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0216 0.0787 0.884
Echinococcus multilocularis glycine receptor subunit beta 0.0012 0.0008 0.0004
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0338 0.1258 0.2224
Brugia malayi Thioredoxin reductase 0.0094 0.0324 0.0572
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.004 0.0114 0.0201
Onchocerca volvulus 0.0338 0.1258 0.2213
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0338 0.1258 0.2224
Toxoplasma gondii PAN domain-containing protein 0.0017 0.0025 0.0195
Schistosoma mansoni ap endonuclease 0.002 0.0037 0.0066
Echinococcus granulosus jumonji domain containing protein 0.0043 0.0125 0.0121
Brugia malayi follicle stimulating hormone receptor 0.0797 0.3017 0.5335
Schistosoma mansoni cytochrome P450 0.0014 0.0017 0.0029
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0033 0.0087 0.0083
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0013 0.0012 0.0021
Echinococcus multilocularis GPI anchor transamidase 0.0345 0.1283 0.1279
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0036 0.0098 1
Loa Loa (eye worm) hypothetical protein 0.0022 0.0044 0.0079
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0037 0.0046
Onchocerca volvulus Netrin receptor homolog 0.0015 0.0018 0.0019
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0012 0.0008 0.0014
Echinococcus multilocularis inositol monophosphatase 1 0.0036 0.0098 0.0095
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0338 0.1258 0.2224
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0027 0.0028
Echinococcus granulosus rhodopsin orphan GPCR 0.0338 0.1258 0.1254
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0027 0.0028
Echinococcus granulosus glycine receptor subunit beta 0.0012 0.0008 0.0004
Brugia malayi Hypothetical tyrosinase-like protein F21C3.2 in chromosome I 0.0066 0.0213 0.0377
Schistosoma mansoni axis inhibition protein axin 0.0022 0.0044 0.0079
Brugia malayi PAN domain containing protein 0.0017 0.0025 0.0044
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0027 0.0028
Echinococcus multilocularis thioredoxin glutathione reductase 0.0094 0.0324 0.032
Echinococcus multilocularis lamin dm0 0.0054 0.0168 0.0164
Schistosoma mansoni aryl hydrocarbon receptor 0.005 0.0154 0.0272
Schistosoma mansoni chromobox protein 0.0141 0.05 0.0885
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0023 0.005 0.0046
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0015 0.0018 0.0014
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.004 0.0114 0.011
Onchocerca volvulus 0.0017 0.0025 0.0031
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0107 0.0189
Brugia malayi beta-lactamase 0.0038 0.0107 0.0189
Echinococcus multilocularis Ankyrin 0.0015 0.0019 0.0015
Brugia malayi Hypothetical tyrosinase-like protein C02C2.1 in chromosome III 0.0066 0.0213 0.0377
Schistosoma mansoni nAChR subunit 0.0012 0.0008 0.0014
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0033 0.0087 0.0723
Schistosoma mansoni biogenic amine receptor 0.0338 0.1258 0.2224
Mycobacterium ulcerans hydrolase 0.0017 0.0027 0.011
Echinococcus multilocularis neuropeptide receptor 0.0338 0.1258 0.1254
Brugia malayi Cyclic-nucleotide gated cation channel 0.0018 0.003 0.0054
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.004 0.0114 0.0201
Loa Loa (eye worm) ACC-1 protein 0.0012 0.0008 0.0014
Echinococcus multilocularis neuropeptide Y receptor 0.0338 0.1258 0.1254
Onchocerca volvulus 0.0017 0.0025 0.0031
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0028 0.0067 0.0119
Echinococcus granulosus rhodopsin orphan GPCR 0.0338 0.1258 0.1254
Loa Loa (eye worm) hypothetical protein 0.0025 0.0057 0.0102
Trypanosoma cruzi cytochrome P450, putative 0.0023 0.0051 0.0148
Loa Loa (eye worm) hypothetical protein 0.0017 0.0026 0.0046
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0078 0.026 0.0459
Brugia malayi hypothetical protein 0.0022 0.0044 0.0079
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0204 0.0745 0.1317
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0338 0.1258 0.2224
Echinococcus multilocularis g protein coupled receptor 0.0338 0.1258 0.1254
Echinococcus multilocularis 6 phosphofructokinase 0.0227 0.083 0.0826
Echinococcus granulosus glycine receptor subunit beta 0.0012 0.0008 0.0004
Trichomonas vaginalis chromobox protein, putative 0.0085 0.0286 0.0487
Brugia malayi Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit 0.0011 0.0004 0.0007
Onchocerca volvulus Putative hydroxypyruvate isomerase 0.002 0.004 0.0057
Schistosoma mansoni ankyrin 23/unc44 0.0015 0.0018 0.0033
Echinococcus multilocularis serotonin receptor 0.1304 0.4958 0.4956
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0027 0.0028
Onchocerca volvulus 0.002 0.004 0.0056
Schistosoma mansoni DNA helicase recq5 0.0018 0.003 0.0054
Echinococcus granulosus glycine receptor subunit alpha 1 0.0012 0.0008 0.0004
Echinococcus granulosus uncharacterized sodium dependent transporter 0.004 0.0114 0.0109
Loa Loa (eye worm) hypothetical protein 0.0634 0.2391 0.4227
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0015 0.0018 0.0033
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0018 0.003 0.0026
Toxoplasma gondii microneme protein MIC17C 0.0017 0.0025 0.0195
Echinococcus granulosus regulator of G protein signaling 3 0.0022 0.0044 0.004
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0338 0.1258 0.2224
Toxoplasma gondii PHD-finger domain-containing protein 0.0031 0.0079 0.0617
Loa Loa (eye worm) hypothetical protein 0.0038 0.0107 0.0189
Onchocerca volvulus 0.0066 0.0213 0.0364
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0338 0.1258 0.1254
Onchocerca volvulus 0.0338 0.1258 0.2213
Echinococcus multilocularis Polycystic kidney disease protein 0.002 0.004 0.0036
Loa Loa (eye worm) hypothetical protein 0.0017 0.0027 0.0048
Trichomonas vaginalis phosphofructokinase, putative 0.0227 0.083 0.1449
Echinococcus multilocularis aryl hydrocarbon receptor 0.0013 0.0012 0.0008
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0023 0.005 0.0145
Brugia malayi PHD-finger family protein 0.0031 0.0079 0.014
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0338 0.1258 0.2224
Loa Loa (eye worm) hypothetical protein 0.0015 0.0019 0.0034
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0037 0.0291
Loa Loa (eye worm) hypothetical protein 0.0022 0.0044 0.0079
Plasmodium vivax thioredoxin reductase, putative 0.0094 0.0324 0.2523
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0061 0.0196 0.1529
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0088 0.0299 0.0529
Brugia malayi Sodium:neurotransmitter symporter family protein 0.004 0.0114 0.0201
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0032 0.0084 0.0834
Onchocerca volvulus Neuropeptide F receptor homolog 0.0338 0.1258 0.2213
Schistosoma mansoni hypothetical protein 0.0023 0.005 0.0088
Echinococcus multilocularis bloom syndrome protein 0.0043 0.0128 0.0124
Echinococcus multilocularis orexin receptor type 2 0.0338 0.1258 0.1254
Brugia malayi Hypothetical tyrosinase-like protein C02C2.1 in chromosome III 0.0066 0.0213 0.0377
Onchocerca volvulus 0.0038 0.0107 0.0175
Brugia malayi NNMT/PNMT/TEMT family protein 0.0284 0.105 0.1857
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0026 0.0061 0.0057
Schistosoma mansoni DNA helicase recq1 0.0018 0.003 0.0054
Loa Loa (eye worm) hypothetical protein 0.0038 0.0107 0.0189
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0013 0.0012 0.0002
Echinococcus multilocularis chromobox protein 2 0.0023 0.005 0.0046
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0038 0.0108 0.0191
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0018 0.003 0.0033
Loa Loa (eye worm) CYP4Cod1 0.0023 0.0051 0.009
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0012 0.0008 0.0004
Brugia malayi Caveolin-1 0.0017 0.0026 0.0046
Loa Loa (eye worm) hypothetical protein 0.0012 0.0008 0.0014
Brugia malayi hypoxia-induced factor 1 0.0155 0.0557 0.0985
Trichomonas vaginalis Heterochromatin protein, putative 0.0023 0.005 0.0068
Schistosoma mansoni hypothetical protein 0.0015 0.0018 0.0033
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.024 0.088 0.9897
Echinococcus granulosus lamin 0.0054 0.0168 0.0164
Loa Loa (eye worm) hypothetical protein 0.0013 0.0012 0.0021
Plasmodium falciparum phd finger protein, putative 0.0031 0.0079 0.0617
Echinococcus granulosus kelch ECH associated protein 1 like 0.0013 0.001 0.0006
Loa Loa (eye worm) cytochrome P450 0.0014 0.0017 0.0029
Loa Loa (eye worm) hypothetical protein 0.0038 0.0108 0.0191
Schistosoma mansoni hemoglobinase (C13 family) 0.1486 0.5655 1
Toxoplasma gondii PHD-finger domain-containing protein 0.0031 0.0079 0.0617
Mycobacterium tuberculosis Probable reductase 0.0216 0.0787 0.884
Echinococcus multilocularis 0.0014 0.0017 0.0013
Echinococcus granulosus PHD finger protein rhinoceros 0.0031 0.0079 0.0075
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0018 0.003 0.0033
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0038 0.0108 0.0104
Entamoeba histolytica phosphofructokinase, putative 0.0227 0.083 0.6361
Brugia malayi hypothetical protein 0.0168 0.0607 0.1074
Trichomonas vaginalis phosphofructokinase, putative 0.0061 0.0196 0.0327
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0018 0.003 0.0234
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0181 0.0657 0.5121
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0013 0.0012 0.0007
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0018 0.003 0.0054
Trichomonas vaginalis inositol monophosphatase, putative 0.0036 0.0098 0.0154
Mycobacterium ulcerans epimerase 0.002 0.004 0.024
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0027 0.0028
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0338 0.1258 0.2224
Loa Loa (eye worm) hypothetical protein 0.0338 0.1258 0.2224
Echinococcus granulosus G protein coupled receptor 139 0.0338 0.1258 0.1254
Onchocerca volvulus 0.0338 0.1258 0.2213
Brugia malayi regulator of G-protein signaling egl-10 0.0022 0.0044 0.0079
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.005 0.0068
Echinococcus granulosus expressed protein 0.0387 0.1445 0.1441
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.004 0.0035
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0012 0.0008 0.0014
Toxoplasma gondii PAN domain-containing protein 0.009 0.0305 0.2375
Schistosoma mansoni voltage-gated potassium channel 0.0015 0.0019 0.0034
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0036 0.0098 0.0489
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0027 0.0028
Loa Loa (eye worm) hypothetical protein 0.0012 0.0008 0.0014
Echinococcus granulosus biogenic amine 5HT receptor 0.1066 0.4044 0.4042
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0018 0.003 0.0026
Echinococcus granulosus chromobox protein 1 0.0141 0.05 0.0496
Entamoeba histolytica hypothetical protein 0.0022 0.0044 0.0056
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.005 0.0068
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0038 0.0107 0.0189
Echinococcus multilocularis Chromo domain 0.0023 0.005 0.0046
Loa Loa (eye worm) melatonin receptor type 1A 0.0338 0.1258 0.2224
Brugia malayi hypothetical protein 0.0022 0.0044 0.0079
Schistosoma mansoni neuropeptide f receptor 76f 0.0338 0.1258 0.2224
Echinococcus multilocularis chromobox protein 1 0.0141 0.05 0.0497
Loa Loa (eye worm) hypothetical protein 0.0023 0.005 0.0088
Schistosoma mansoni blooms syndrome DNA helicase 0.0034 0.0093 0.0164
Loa Loa (eye worm) hypothetical protein 0.0338 0.1258 0.2224
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0023 0.005 0.0068
Schistosoma mansoni neuropeptide F-like receptor 0.0338 0.1258 0.2224
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0013 0.0012 0.0002
Brugia malayi CHD4 protein 0.0023 0.005 0.0088
Echinococcus granulosus RUN 0.002 0.004 0.0035
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0027 0.0028
Brugia malayi putative neuropeptide receptor 0.0338 0.1258 0.2224
Brugia malayi jmjC domain containing protein 0.0037 0.0104 0.0184
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0234 0.0857 0.1515
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0023 0.005 0.0088
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0242 0.0889 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0108 0.0171
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0338 0.1258 0.1254
Trypanosoma brucei GPI-anchor transamidase subunit 8 (GPI8) 0.0345 0.1283 0.4773
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0012 0.0008 0.0014
Toxoplasma gondii hypothetical protein 0.0017 0.0025 0.0195
Onchocerca volvulus 0.0017 0.0025 0.0031
Schistosoma mansoni protein tyrosine phosphatase non-receptor type nt1 0.0088 0.0299 0.0529
Echinococcus granulosus g protein coupled receptor 0.0338 0.1258 0.1254
Loa Loa (eye worm) glutaminase 0.0269 0.0992 0.1753
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0031 0.0081 0.0143
Schistosoma mansoni regulator of G protein signaling 0.0022 0.0044 0.0079
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0107 0.0189
Brugia malayi neuropeptide F receptor 0.0338 0.1258 0.2224
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0023 0.005 0.0046
Echinococcus granulosus flap endonuclease 1 0.0027 0.0065 0.006
Echinococcus granulosus kelch ECH associated protein 1 0.0013 0.001 0.0006
Loa Loa (eye worm) hypothetical protein 0.0338 0.1258 0.2224
Mycobacterium ulcerans putative regulatory protein 0.0037 0.0104 0.0897
Trichomonas vaginalis chromobox protein, putative 0.0023 0.005 0.0068
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0027 0.0028
Onchocerca volvulus 0.0017 0.0025 0.0031
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0014 0.0017 0.0019
Loa Loa (eye worm) hypothetical protein 0.091 0.3447 0.6096
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0038 0.0107 0.0924
Echinococcus multilocularis rhodopsin orphan GPCR 0.0338 0.1258 0.1254
Echinococcus granulosus neuropeptides capa receptor 0.0338 0.1258 0.1254
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0338 0.1258 0.2224
Schistosoma mansoni biogenic amine (5HT) receptor 0.1304 0.4958 0.8768
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0078 0.026 0.2858
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0012 0.0008 0.0004
Trypanosoma cruzi trypanothione reductase, putative 0.0094 0.0324 0.1166
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0012 0.0008 0.0004
Schistosoma mansoni inositol monophosphatase 0.0036 0.0098 0.0174
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0033 0.0087 0.0679
Schistosoma mansoni chromobox protein 0.0023 0.005 0.0088
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0014 0.0017 0.0019
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0027 0.0028
Echinococcus granulosus single minded 2 0.0044 0.013 0.0126
Schistosoma mansoni family C13 non-peptidase homologue (C13 family) 0.1486 0.5655 1
Schistosoma mansoni sodium-dependent amino acid transporter 0.004 0.0114 0.0201
Toxoplasma gondii phosphofructokinase PFKII 0.0061 0.0196 0.1529
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0015 0.0018 0.0015
Loa Loa (eye worm) hypothetical protein 0.0034 0.009 0.016
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0098 0.0366
Brugia malayi Immunoglobulin I-set domain containing protein 0.0015 0.0018 0.0033
Echinococcus multilocularis somatostatin receptor 0.0338 0.1258 0.1254
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0044 0.0058
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0227 0.083 0.967
Schistosoma mansoni sodium/chloride dependent transporter 0.004 0.0114 0.0201
Brugia malayi PAN domain containing protein 0.0017 0.0025 0.0044
Plasmodium falciparum cysteine repeat modular protein 1 0.0018 0.003 0.0234
Onchocerca volvulus Alhambra homolog 0.0031 0.0079 0.0126
Toxoplasma gondii microneme protein MIC4 0.0017 0.0025 0.0195
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0338 0.1258 0.1254
Echinococcus granulosus Chromo domain 0.0023 0.005 0.0046
Echinococcus granulosus biogenic amine 5HT receptor 0.1304 0.4958 0.4956
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0022 0.0044 0.0079
Onchocerca volvulus 0.0338 0.1258 0.2213
Echinococcus granulosus dro:myosuppressin receptor 0.0338 0.1258 0.1254
Giardia lamblia PHD finger protein 15 0.0031 0.0079 0.0412
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0015 0.0018 0.0014
Brugia malayi Serotonin receptor 0.0338 0.1258 0.2224
Echinococcus multilocularis rhodopsin orphan GPCR 0.0338 0.1258 0.1254
Brugia malayi Doublecortin family protein 0.002 0.004 0.007
Mycobacterium ulcerans arylsulfatase AtsB 0.0017 0.0027 0.011
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0088 0.0299 0.0295
Loa Loa (eye worm) hypothetical protein 0.0338 0.1258 0.2224
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0027 0.0028
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0044 0.0058
Schistosoma mansoni amine GPCR 0.0338 0.1258 0.2224
Echinococcus granulosus Chromobox protein 3 0.0023 0.005 0.0046
Toxoplasma gondii aldehyde dehydrogenase 0.0122 0.0431 0.3357
Echinococcus multilocularis fmrfamide receptor 0.0338 0.1258 0.1254
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0033 0.0087 0.0282
Mycobacterium leprae Conserved hypothetical protein 0.0014 0.0017 0.0058
Loa Loa (eye worm) RGS-3 protein 0.0022 0.0044 0.0079
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0023 0.005 0.0068
Schistosoma mansoni inositol monophosphatase 0.0036 0.0098 0.0174
Chlamydia trachomatis endonuclease IV 0.0078 0.026 1
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0175 0.0631 0.0627
Echinococcus multilocularis conserved hypothetical protein 0.0667 0.2516 0.2513
Loa Loa (eye worm) hypothetical protein 0.0338 0.1258 0.2224
Echinococcus multilocularis neuropeptides capa receptor 0.0338 0.1258 0.1254
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0181 0.0657 0.1162
Echinococcus multilocularis voltage gated potassium channel 0.0025 0.0056 0.0053
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0107 0.0355
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0037 0.0046
Leishmania major hypothetical protein, conserved 0.0018 0.003 0.0069
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.1486 0.5655 1
Echinococcus granulosus chromobox protein 1 0.0141 0.05 0.0496
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0107 0.0168
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0038 0.0108 0.036
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0234 0.0857 0.1515
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0338 0.1258 0.2224
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0033 0.0087 0.0723
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0012 0.0008 0.0004
Loa Loa (eye worm) serotonin transporter b 0.0234 0.0857 0.1515
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0338 0.1258 0.2224
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0025 0.0056 0.0052
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.1486 0.5655 1
Loa Loa (eye worm) hypothetical protein 0.0338 0.1258 0.2224
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0038 0.0108 0.036
Brugia malayi Cytochrome P450 family protein 0.0023 0.0051 0.009
Onchocerca volvulus 0.0338 0.1258 0.2213
Schistosoma mansoni neuropeptide receptor 0.0338 0.1258 0.2224
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0107 0.0168
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0338 0.1258 0.2224
Schistosoma mansoni hypothetical protein 0.0167 0.06 0.1061
Trypanosoma cruzi cysteine peptidase, Clan CD, family C13, putative 0.0345 0.1283 0.475
Schistosoma mansoni hypothetical protein 0.0014 0.0017 0.0029
Brugia malayi excitatory GABA receptor EXP-1A 0.0012 0.0008 0.0014
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0038 0.0108 0.0191
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0014 0.0017 0.0019
Echinococcus granulosus allatostatin A receptor 0.0338 0.1258 0.1254
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0033 0.0087 0.0282
Echinococcus granulosus neuropeptide receptor A26 0.0338 0.1258 0.1254
Echinococcus multilocularis serotonin transporter 0.0234 0.0857 0.0853
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0338 0.1258 0.1254
Giardia lamblia NADH oxidase lateral transfer candidate 0.0033 0.0087 0.0476
Brugia malayi Regulator of G protein signaling domain containing protein 0.0022 0.0044 0.0079
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.004 0.0114 0.0201
Echinococcus granulosus peregrin 0.0031 0.0079 0.0075
Schistosoma mansoni hypothetical protein 0.0051 0.0156 0.0277
Schistosoma mansoni regulator of G protein signaling 0.0022 0.0044 0.0079
Loa Loa (eye worm) solute carrier family 6 member 4 0.0234 0.0857 0.1515
Loa Loa (eye worm) hypothetical protein 0.0015 0.0018 0.0033
Loa Loa (eye worm) hypothetical protein 0.0284 0.105 0.1857
Loa Loa (eye worm) LGC-31 protein 0.0012 0.0008 0.0014
Brugia malayi A-kinase anchor protein 10, precursor 0.0022 0.0044 0.0079
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0027 0.0028
Loa Loa (eye worm) hypothetical protein 0.0338 0.1258 0.2224
Mycobacterium tuberculosis Conserved protein 0.0038 0.0107 0.1033
Echinococcus multilocularis g protein coupled receptor 0.0338 0.1258 0.1254
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0012 0.0008 0.0014
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0012 0.0008 0.0004
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.004 0.0114 0.0201
Brugia malayi PAN domain containing protein 0.0017 0.0025 0.0044
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0181 0.0657 0.1162
Brugia malayi bHLH-PAS transcription factor 0.0037 0.0104 0.0184
Mycobacterium ulcerans sugar phosphate isomerases/epimerases 0.002 0.004 0.024
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.004 0.0035
Schistosoma mansoni voltage-gated potassium channel 0.0084 0.0283 0.05
Mycobacterium tuberculosis Possible hydrolase 0.0017 0.0027 0.0123
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0059 0.0188 0.1763
Schistosoma mansoni axis inhibition protein axin 0.0022 0.0044 0.0079
Mycobacterium tuberculosis Probable lipase LipE 0.0038 0.0107 0.1033
Brugia malayi Common central domain of tyrosinase family protein 0.0066 0.0213 0.0377
Schistosoma mansoni alpha-1 adrenergic receptor 0.0338 0.1258 0.2224
Leishmania major protein kinase, putative 0.0023 0.0049 0.0141
Brugia malayi Sodium:neurotransmitter symporter family protein 0.004 0.0114 0.0201
Loa Loa (eye worm) hypothetical protein 0.0338 0.1258 0.2224
Brugia malayi exodeoxyribonuclease III family protein 0.002 0.0037 0.0066
Loa Loa (eye worm) hypothetical protein 0.0018 0.003 0.0053
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0012 0.0008 0.0014
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0059 0.0188 0.0333
Echinococcus granulosus neuropeptide Y receptor 0.0338 0.1258 0.1254
Schistosoma mansoni amine GPCR 0.0818 0.3097 0.5476
Loa Loa (eye worm) hypothetical protein 0.0025 0.0057 0.0102
Brugia malayi G protein-coupled receptor 0.0338 0.1258 0.2224
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0033 0.0087 0.0679
Plasmodium vivax hypothetical protein, conserved 0.0038 0.0107 0.0832
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.004 0.0114 0.0109
Echinococcus multilocularis microtubule associated protein 2 0.1438 0.5472 0.547
Onchocerca volvulus 0.0037 0.0104 0.017
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.002 0.0037 0.0033
Brugia malayi hypothetical protein 0.0023 0.005 0.0089
Mycobacterium tuberculosis Probable lipase LipD 0.0038 0.0107 0.1033
Schistosoma mansoni biogenic amine receptor 0.0338 0.1258 0.2224
Echinococcus granulosus axis inhibition protein axin 0.0022 0.0044 0.004
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0023 0.005 0.0088
Brugia malayi PAN domain containing protein 0.0017 0.0025 0.0044
Loa Loa (eye worm) hypothetical protein 0.0062 0.0198 0.0351
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0227 0.083 0.9423
Brugia malayi Valyl-tRNA synthetase 0.0023 0.005 0.0088
Loa Loa (eye worm) hypothetical protein 0.0017 0.0025 0.0044
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0038 0.0107 0.1033
Toxoplasma gondii kringle domain-containing protein 0.0018 0.003 0.0234
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0059 0.0188 0.0333
Brugia malayi Peptidase C13 family protein 0.1486 0.5655 1
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0338 0.1258 0.2213
Loa Loa (eye worm) hypothetical protein 0.0338 0.1258 0.2224
Brugia malayi hypothetical protein 0.004 0.0114 0.0201
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0338 0.1258 0.1254
Echinococcus granulosus thioredoxin glutathione reductase 0.0094 0.0324 0.032
Onchocerca volvulus 0.0038 0.0107 0.0175
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0012 0.0008 0.0014
Mycobacterium ulcerans hypothetical protein 0.0038 0.0107 0.0924
Onchocerca volvulus 0.0062 0.0198 0.0337
Loa Loa (eye worm) PAN domain-containing protein 0.0017 0.0025 0.0044
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0023 0.005 0.0068
Schistosoma mansoni amine GPCR 0.0338 0.1258 0.2224
Brugia malayi 6-phosphofructokinase 0.0227 0.083 0.1467
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0023 0.005 0.0068
Brugia malayi Sulfatase family protein 0.0017 0.0027 0.0048
Loa Loa (eye worm) hypothetical protein 0.0022 0.0044 0.0079
Loa Loa (eye worm) hypothetical protein 0.1304 0.4958 0.8768
Echinococcus granulosus serotonin transporter 0.0234 0.0857 0.0853
Onchocerca volvulus 0.0013 0.0012 0.0007
Loa Loa (eye worm) hypothetical protein 0.0338 0.1258 0.2224
Brugia malayi regulator of G-protein signaling rgs-7 0.0022 0.0044 0.0079
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.1486 0.5655 1
Trichomonas vaginalis mucin-desulfating sulfatase, putative 0.0017 0.0027 0.0028
Echinococcus multilocularis rhodopsin orphan GPCR 0.0338 0.1258 0.1254
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0023 0.005 0.0046
Mycobacterium leprae Probable lipase LipE 0.0038 0.0107 0.1095
Treponema pallidum NADH oxidase 0.0033 0.0087 0.0606
Plasmodium falciparum amino acid transporter, putative 0.004 0.0114 0.0885
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0216 0.0787 0.884
Loa Loa (eye worm) hypothetical protein 0.004 0.0114 0.0201
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0018 0.003 0.0054
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0098 0.0324
Loa Loa (eye worm) hypothetical protein 0.0012 0.0008 0.0014
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.004 0.0114 0.0201
Plasmodium vivax GPI-anchor transamidase, putative 0.0345 0.1283 1
Schistosoma mansoni chromobox protein 0.0141 0.05 0.0885
Trypanosoma cruzi trypanothione reductase, putative 0.0033 0.0087 0.0282
Schistosoma mansoni amine GPCR 0.0338 0.1258 0.2224
Loa Loa (eye worm) hypothetical protein 0.0168 0.0607 0.1074
Onchocerca volvulus 0.0054 0.0168 0.0284
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0032 0.0084 0.0773
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.005 0.0068
Loa Loa (eye worm) hypothetical protein 0.0054 0.0168 0.0297
Echinococcus granulosus neuropeptide receptor 0.0338 0.1258 0.1254
Brugia malayi cytochrome P450 0.0014 0.0017 0.0029
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0027 0.0028
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0027 0.0028
Echinococcus granulosus rhodopsin orphan GPCR 0.0338 0.1258 0.1254
Schistosoma mansoni sodium/chloride dependent transporter 0.0234 0.0857 0.1515
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0033 0.0087 0.0324
Loa Loa (eye worm) hypothetical protein 0.0338 0.1258 0.2224
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0077 0.0257 0.0455
Mycobacterium tuberculosis Probable oxidoreductase 0.024 0.088 0.9897
Echinococcus multilocularis neuropeptide Y receptor 0.0338 0.1258 0.1254
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0711 0.2687 1
Echinococcus granulosus beta-adrenergic receptor kinase 0.0028 0.0071 0.0067
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0338 0.1258 0.1254
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0018 0.003 0.0236
Onchocerca volvulus 0.0338 0.1258 0.2213
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0122 0.0431 0.0427
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.002 0.0037 0.0066
Schistosoma mansoni tyrosinase precursor 0.0066 0.0213 0.0377
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0338 0.1258 0.2224
Loa Loa (eye worm) PAN domain-containing protein 0.0017 0.0025 0.0044
Echinococcus multilocularis Regulator of G protein signaling 20 0.0022 0.0044 0.0041
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0107 0.0168
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0023 0.005 0.0068
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0034 0.009 0.016
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.004 0.0114 0.0885
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0018 0.003 0.0027
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0026 0.0061 0.0058
Brugia malayi jmjC domain containing protein 0.01 0.0346 0.0613
Loa Loa (eye worm) hypothetical protein 0.0338 0.1258 0.2224
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0027 0.0065 0.0504
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0033 0.0087 0.0282
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0338 0.1258 0.1254
Brugia malayi PAN domain containing protein 0.0017 0.0025 0.0044
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0027 0.0028
Loa Loa (eye worm) jmjC domain-containing protein 0.0037 0.0104 0.0184
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0031 0.0081 0.0143
Loa Loa (eye worm) hypothetical protein 0.0012 0.0008 0.0014
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0033 0.0087 0.0679
Echinococcus multilocularis hyperpolarization activated cyclic 0.0018 0.003 0.0027
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.004 0.0114 0.011
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0012 0.0008 0.0004
Brugia malayi beta-lactamase family protein 0.0038 0.0107 0.0189
Echinococcus granulosus Ankyrin 0.0015 0.0019 0.0015
Echinococcus granulosus hypothetical protein 0.1005 0.3812 0.3809
Entamoeba histolytica Flap nuclease, putative 0.0027 0.0065 0.0219
Loa Loa (eye worm) thioredoxin reductase 0.0094 0.0324 0.0572
Toxoplasma gondii 1,3(4)-beta-glucanase 0.0017 0.0025 0.0195
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0038 0.0108 0.0642
Toxoplasma gondii hypothetical protein 0.0017 0.0025 0.0195
Onchocerca volvulus 0.0234 0.0857 0.1503
Schistosoma mansoni 6-phosphofructokinase 0.0227 0.083 0.1467
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.004 0.0114 0.0201
Onchocerca volvulus 0.0023 0.005 0.0074
Trichomonas vaginalis phosphofructokinase, putative 0.0227 0.083 0.1449
Brugia malayi glutathione reductase 0.0094 0.0324 0.0572
Echinococcus granulosus g protein coupled receptor 0.0338 0.1258 0.1254
Loa Loa (eye worm) PXA domain-containing protein 0.0022 0.0044 0.0079
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0012 0.0008 0.0014
Echinococcus granulosus cytochrome P450 2K1 0.0014 0.0017 0.0012
Echinococcus granulosus rhodopsin orphan GPCR 0.0338 0.1258 0.1254
Schistosoma mansoni voltage-gated potassium channel 0.0025 0.0056 0.01
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0012 0.0008 0.0014
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0027 0.0028
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0015 0.0018 0.0014
Mycobacterium tuberculosis Conserved protein 0.0038 0.0107 0.1033
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0038 0.0108 0.0104
Brugia malayi hypothetical protein 0.0243 0.0894 0.158
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0098 0.0154
Echinococcus granulosus tissue type plasminogen activator 0.0018 0.003 0.0026
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0033 0.0087 0.0723
Loa Loa (eye worm) inositol-1 0.0036 0.0098 0.0174
Brugia malayi PAN domain containing protein 0.0017 0.0025 0.0044
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.004 0.0114 0.0201
Onchocerca volvulus GPI ethanolamine phosphate transferase 1 homolog 0.0017 0.0027 0.0035
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0033 0.0087 0.0324
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0018 0.003 0.0026
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0012 0.0008 0.0004
Loa Loa (eye worm) hypothetical protein 0.0234 0.0857 0.1515
Echinococcus multilocularis G protein coupled receptor 139 0.0338 0.1258 0.1254
Loa Loa (eye worm) hypothetical protein 0.004 0.0114 0.0201
Plasmodium falciparum flap endonuclease 1 0.0027 0.0065 0.0504
Schistosoma mansoni nAChR subunit 0.0012 0.0008 0.0014
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0012 0.0008 0.0004
Loa Loa (eye worm) neuropeptide F receptor 0.0338 0.1258 0.2224
Loa Loa (eye worm) hypothetical protein 0.0017 0.0025 0.0044
Trichomonas vaginalis phosphofructokinase, putative 0.0227 0.083 0.1449
Onchocerca volvulus 0.0338 0.1258 0.2213
Echinococcus multilocularis axis inhibition protein axin 0.0022 0.0044 0.0041
Schistosoma mansoni aldehyde dehydrogenase 0.0122 0.0431 0.0761
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.004 0.0114 0.4108
Loa Loa (eye worm) hypothetical protein 0.004 0.0114 0.0201
Onchocerca volvulus 0.0204 0.0745 0.1305
Onchocerca volvulus 0.004 0.0114 0.0187
Brugia malayi Death domain containing protein 0.0015 0.0018 0.0033
Plasmodium vivax 6-phosphofructokinase, putative 0.0061 0.0196 0.1529
Toxoplasma gondii microneme protein MIC17B 0.0017 0.0025 0.0195
Brugia malayi glutaminase DH11.1 0.0269 0.0992 0.1753
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0012 0.0008 0.0014
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0107 0.0168
Mycobacterium ulcerans endonuclease IV 0.0078 0.026 0.2494
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0018 0.003 0.0027
Mycobacterium ulcerans arylsulfatase AtsD 0.0017 0.0027 0.011
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.004 0.0036
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0012 0.0008 0.0014
Echinococcus multilocularis g-protein coupled receptor 0.0338 0.1258 0.1254
Trichomonas vaginalis phosphofructokinase, putative 0.0061 0.0196 0.0327
Echinococcus granulosus nAChR subunit 0.0012 0.0008 0.0004
Schistosoma mansoni serine/threonine protein kinase 0.0031 0.0081 0.0143
Loa Loa (eye worm) 6-phosphofructokinase 0.0227 0.083 0.1467
Loa Loa (eye worm) hypothetical protein 0.0035 0.0094 0.0167
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0012 0.0008 0.0014
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0338 0.1258 0.2224
Onchocerca volvulus 0.0338 0.1258 0.2213
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0023 0.0051 0.0355
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0078 0.026 0.2025
Echinococcus multilocularis neuropeptide FF receptor 2 0.0338 0.1258 0.1254
Mycobacterium leprae conserved hypothetical protein 0.0038 0.0107 0.1095
Trichomonas vaginalis DNA helicase recq, putative 0.0043 0.0128 0.0206
Loa Loa (eye worm) phosphofructokinase 0.0227 0.083 0.1467
Echinococcus multilocularis beta adrenergic receptor kinase 0.0028 0.0071 0.0067
Loa Loa (eye worm) PAN domain-containing protein 0.0017 0.0025 0.0044
Mycobacterium tuberculosis Probable sulfatase 0.0017 0.0027 0.0123
Brugia malayi larval opioid receptor 0.0338 0.1258 0.2224
Brugia malayi Pre-SET motif family protein 0.1265 0.4809 0.8503
Trypanosoma brucei C-8 sterol isomerase, putative 0.0711 0.2687 1
Brugia malayi PAN domain containing protein 0.0017 0.0025 0.0044
Schistosoma mansoni sodium/chloride dependent transporter 0.004 0.0114 0.0202
Trichomonas vaginalis Phosphoglycerol transferase I, putative 0.0017 0.0027 0.0028
Loa Loa (eye worm) hypothetical protein 0.0018 0.003 0.0054
Schistosoma mansoni hypothetical protein 0.002 0.004 0.007
Trypanosoma brucei cytochrome P450, putative 0.0023 0.0051 0.019
Mycobacterium ulcerans lipase LipD 0.0038 0.0107 0.0924
Brugia malayi PAN domain containing protein 0.0017 0.0025 0.0044
Trichomonas vaginalis chromobox protein, putative 0.0085 0.0286 0.0487

Activities

Activity type Activity value Assay description Source Reference
EC50 (functional) = 0.0000025 M Effective concentration of the compound against HIV-1 was determined ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SN12C Renal cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the ACHN Renal cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the NCI-H23 Non-Small Cell Lung cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the UO-31 Renal cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HL-60(TB) Leukemia cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SK-MEL-5 Melanoma cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SF-539 Central Nervous System cell line. (Class of assay: confirmatory) ChEMBL. No reference
IC50 (functional) > 0.00021 M Inhibitory concentration of the compound against HIV-1 was determined ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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