Detailed information for compound 831533

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 425.461 | Formula: C20H19N5O4S
  • H donors: 1 H acceptors: 3 LogP: 1.73 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCc1nn2c(s1)nc(cc2=O)COc1ccc(cc1OC)C=C(C(=O)N)C#N
  • InChi: 1S/C20H19N5O4S/c1-3-4-17-24-25-18(26)9-14(23-20(25)30-17)11-29-15-6-5-12(8-16(15)28-2)7-13(10-21)19(22)27/h5-9H,3-4,11H2,1-2H3,(H2,22,27)/b13-7+
  • InChiKey: YPTDQIYIUGZTGR-NTUHNPAUSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis insulin receptor 0.0485 0.4085 0.4958
Trichomonas vaginalis CMGC family protein kinase 0.0142 0.0745 0.2765
Plasmodium falciparum NIMA related kinase 1 0.015 0.0823 0.7291
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0192 0.1235 0.1318
Echinococcus granulosus rho-associated protein kinase 1 0.0352 0.2788 0.2697
Loa Loa (eye worm) TK/FER protein kinase 0.0112 0.0457 0.0488
Echinococcus multilocularis dual specificity 0.0153 0.0852 0.1024
Loa Loa (eye worm) TK/FER protein kinase 0.0112 0.0457 0.0488
Schistosoma mansoni tyrosine kinase 0.0277 0.2057 0.2712
Trypanosoma cruzi polo-like protein kinase, putative 0.0293 0.2217 0.9298
Echinococcus multilocularis cyclin dependent kinase 7 0.0122 0.055 0.0657
Loa Loa (eye worm) AGC/PKN protein kinase 0.0319 0.2465 0.2631
Toxoplasma gondii casein kinase I 0.0121 0.0537 0.1335
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0153 0.0848 0.1019
Giardia lamblia Kinase, NEK 0.015 0.0823 0.2834
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0132 0.0647 0.0691
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0132 0.0649 0.0777
Loa Loa (eye worm) hypothetical protein 0.0118 0.051 0.0545
Trichomonas vaginalis CAMK family protein kinase 0.0293 0.2217 0.885
Trichomonas vaginalis CMGC family protein kinase 0.0094 0.0278 0.0834
Trichomonas vaginalis CMGC family protein kinase 0.01 0.0341 0.1093
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0105 0.0387 0.0413
Leishmania major casein kinase, putative 0.0121 0.0537 0.1264
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0153 0.0848 0.2779
Entamoeba histolytica protein kinase domain containing protein 0.0088 0.0219 0.0441
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0125 0.0583 0.1546
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.027 0.1991 0.2126
Echinococcus multilocularis hypothetical protein 0.0076 0.0105 0.0114
Echinococcus multilocularis mitogen activated protein kinase 11 0.031 0.2373 0.2875
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0246 0.176 0.2129
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0125 0.0583 0.1399
Onchocerca volvulus 0.1029 0.9368 1
Brugia malayi serine/threonine-protein kinase 6 0.01 0.0335 0.0358
Leishmania major protein kinase, putative 0.01 0.0335 0.0303
Loa Loa (eye worm) TK/FER protein kinase 0.0112 0.0457 0.0488
Echinococcus granulosus raf serine:threonine protein kinase 0.0108 0.0415 0.0294
Plasmodium vivax serine/threonine protein kinase 6, putative 0.01 0.0335 0.2837
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0159 0.0914 0.1098
Schistosoma mansoni serine/threonine protein kinase 0.0116 0.0492 0.0637
Loa Loa (eye worm) hypothetical protein 0.0206 0.1362 0.1454
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0086 0.0196 0.0225
Trypanosoma brucei protein kinase, putative 0.0103 0.036 0.0399
Brugia malayi cyclin-dependent kinase 9 0.0088 0.0219 0.0234
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0169 0.1005 0.3843
Brugia malayi Protein kinase domain containing protein 0.0322 0.2496 0.2664
Loa Loa (eye worm) gastrulation defective protein 1 0.014 0.0727 0.0776
Brugia malayi Protein kinase domain containing protein 0.0646 0.5645 0.6026
Echinococcus multilocularis nervana 2 0.0132 0.0649 0.0777
Plasmodium falciparum protein kinase 5 0.0132 0.0643 0.4998
Trichomonas vaginalis CMGC family protein kinase 0.0132 0.0643 0.2341
Echinococcus granulosus fibroblast growth factor receptor 4 0.0267 0.1962 0.1861
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0125 0.0583 0.0465
Echinococcus multilocularis expressed protein 0.0093 0.0272 0.0317
Brugia malayi Protein kinase domain 0.0096 0.0302 0.0322
Loa Loa (eye worm) TK/FER protein kinase 0.0112 0.0457 0.0488
Loa Loa (eye worm) TK/EPH protein kinase 0.0142 0.0749 0.0799
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.0153 0.0852 0.091
Brugia malayi C1-like domain containing protein 0.0245 0.1749 0.1867
Schistosoma mansoni serine/threonine protein kinase 0.0287 0.2155 0.2842
Trichomonas vaginalis CAMK family protein kinase 0.01 0.0337 0.1078
Schistosoma mansoni serine/threonine protein kinase 0.018 0.1117 0.1466
Echinococcus granulosus casein kinase I alpha 0.0121 0.0537 0.0419
Echinococcus granulosus aurora kinase A 0.01 0.0335 0.0214
Schistosoma mansoni serine/threonine protein kinase 0.0203 0.1339 0.1761
Entamoeba histolytica casein kinase 1, putative 0.0121 0.0537 0.1423
Trichomonas vaginalis CAMK family protein kinase 0.01 0.0337 0.1078
Loa Loa (eye worm) hypothetical protein 0.0153 0.0856 0.0914
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.015 0.0823 0.2662
Trichomonas vaginalis CMGC family protein kinase 0.0132 0.0643 0.2341
Echinococcus multilocularis 0.0186 0.1169 0.1409
Echinococcus granulosus Glutaredoxin protein 5 0.0132 0.0649 0.0532
Trichomonas vaginalis CMGC family protein kinase 0.0112 0.0448 0.1538
Echinococcus multilocularis serine:threonine protein kinase N2 0.018 0.1117 0.1346
Echinococcus granulosus tyrosine protein kinase shark 0.0341 0.2677 0.2585
Trypanosoma cruzi cdc2-related kinase 3 0.0132 0.0643 0.2214
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0153 0.0848 0.2779
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0153 0.0848 0.0905
Trichomonas vaginalis CAMK family protein kinase 0.01 0.0337 0.1078
Echinococcus granulosus roundabout 2 0.0156 0.0884 0.077
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0112 0.0448 0.0479
Brugia malayi Protein kinase domain containing protein 0.018 0.1117 0.1192
Trichomonas vaginalis CAMK family protein kinase 0.01 0.0337 0.1078
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0094 0.0278 0.0574
Trichomonas vaginalis CAMK family protein kinase 0.01 0.0337 0.1078
Loa Loa (eye worm) hypothetical protein 0.0119 0.0525 0.0561
Loa Loa (eye worm) hypothetical protein 0.0111 0.0441 0.047
Schistosoma mansoni ephrin receptor 0.0124 0.0566 0.0736
Schistosoma mansoni protein kinase 0.0096 0.0302 0.0385
Echinococcus multilocularis casein kinase I gamma 0.0232 0.1624 0.1964
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0203 0.1339 0.1429
Echinococcus granulosus dual specificity 0.0231 0.1607 0.1501
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0121 0.0537 0.174
Brugia malayi MAP kinase sur-1 0.0094 0.0278 0.0297
Entamoeba histolytica protein kinase, putative 0.008 0.0144 0.0209
Echinococcus granulosus dual specificity 0.0153 0.0852 0.0738
Echinococcus multilocularis serine:threonine protein kinase 38 0.018 0.1117 0.1346
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0148 0.0807 0.0969
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0148 0.0807 0.2587
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0082 0.0162 0.0038
Brugia malayi Cam kinase protein 1 0.0153 0.0848 0.0905
Echinococcus granulosus NCK adaptor protein 0.0097 0.0308 0.0187
Brugia malayi Temporarily assigned gene name protein 59 0.0119 0.0525 0.0561
Giardia lamblia Kinase, CMGC GSK 0.0142 0.0745 0.2435
Echinococcus granulosus hypothetical protein 0.0129 0.0618 0.05
Giardia lamblia Kinase, CAMK CAMKL 0.0109 0.0419 0.0759
Trypanosoma cruzi polo-like protein kinase, putative 0.0293 0.2217 0.9298
Loa Loa (eye worm) CDC7 protein kinase 0.01 0.0341 0.0364
Trichomonas vaginalis CAMK family protein kinase 0.01 0.0337 0.1078
Entamoeba histolytica protein kinase, putative 0.0313 0.2403 0.7184
Echinococcus granulosus protein kinase c epsilon type 0.0235 0.1644 0.1539
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0381 0.3073 0.3259
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0153 0.0848 0.0905
Trichomonas vaginalis AGC family protein kinase 0.0322 0.2496 1
Schistosoma mansoni tyrosine kinase 0.0485 0.4085 0.54
Echinococcus granulosus cyclin dependent kinase 5 0.0132 0.0643 0.0525
Brugia malayi Protein kinase domain containing protein 0.018 0.1113 0.1188
Echinococcus granulosus growth factor receptor bound protein 2 0.0101 0.0346 0.0225
Brugia malayi RhoGAP domain containing protein 0.011 0.0433 0.0463
Entamoeba histolytica serine/threonine protein kinase, putative 0.01 0.0337 0.0805
Schistosoma mansoni serine/threonine-protein kinase 0.0182 0.1129 0.1482
Loa Loa (eye worm) CAMK/PHK protein kinase 0.018 0.1113 0.1188
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0096 0.0302 0.0354
Loa Loa (eye worm) G protein-coupled receptor kinase 1 0.0163 0.0953 0.1017
Schistosoma mansoni tyrosine kinase 0.0101 0.0344 0.0441
Trypanosoma brucei polo-like protein kinase 0.0293 0.2217 0.8749
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0142 0.0745 0.0795
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0094 0.0278 0.0297
Giardia lamblia Aurora kinase 0.01 0.0335 0.0327
Trichomonas vaginalis CAMK family protein kinase 0.0293 0.2217 0.885
Loa Loa (eye worm) hypothetical protein 0.0177 0.1089 0.1163
Brugia malayi Doublecortin family protein 0.0166 0.0976 0.1041
Schistosoma mansoni tyrosine kinase 0.0152 0.0846 0.1107
Schistosoma mansoni serine/threonine protein kinase 0.0231 0.1607 0.2115
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0267 0.1962 0.2374
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0155 0.0871 0.1047
Entamoeba histolytica serine/threonine protein kinase STE20, putative 0.0095 0.0288 0.0653
Echinococcus granulosus Vam6:Vps39 protein 0.0119 0.0525 0.0406
Brugia malayi putative serine/threonine kinase SADA gamma 0.01 0.0337 0.036
Trichomonas vaginalis CMGC family protein kinase 0.0153 0.0852 0.3208
Echinococcus granulosus mitogen activated protein kinase 14 0.031 0.2373 0.2278
Leishmania major casein kinase II, putative 0.0112 0.0448 0.0841
Entamoeba histolytica protein kinase, putative 0.0153 0.0848 0.2383
Echinococcus multilocularis tyrosine protein kinase 0.0312 0.2393 0.29
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0121 0.0537 0.0573
Echinococcus multilocularis cyclin dependent kinase 1 0.0132 0.0643 0.0769
Schistosoma mansoni serine/threonine protein kinase 0.0148 0.0807 0.1055
Echinococcus multilocularis mitogen activated protein kinase 11 0.031 0.2373 0.2875
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0125 0.0583 0.0696
Giardia lamblia Kinase, STE STE20 0.0096 0.0302 0.0155
Mycobacterium ulcerans hypothetical protein 0.0109 0.042 0.5
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0246 0.176 0.2129
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0096 0.0302 0.018
Loa Loa (eye worm) TK/ALK protein kinase 0.0605 0.5245 0.5598
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0125 0.0583 0.0696
Trichomonas vaginalis AGC family protein kinase 0.01 0.0335 0.107
Trichomonas vaginalis CK1 family protein kinase 0.0121 0.0537 0.1905
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.01 0.0337 0.036
Brugia malayi Protein kinase domain containing protein 0.1029 0.9368 1
Echinococcus granulosus tyrosine protein kinase Fyn 0.0246 0.176 0.1657
Onchocerca volvulus 0.01 0.0341 0.0334
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0097 0.0308 0.0329
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0132 0.0643 0.0686
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0182 0.1129 0.4401
Loa Loa (eye worm) protein kinase domain-containing protein 0.0232 0.1624 0.1734
Echinococcus multilocularis serine:threonine protein kinase receptor R3 0.0117 0.0497 0.0591
Echinococcus granulosus mitogen activated protein kinase 11 0.031 0.2373 0.2278
Echinococcus granulosus dual specificity protein kinase clk2 0.0169 0.1005 0.0892
Schistosoma mansoni serine/threonine protein kinase 0.0235 0.1644 0.2165
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0246 0.176 0.2129
Echinococcus multilocularis myosin iiia 0.0095 0.0288 0.0337
Trichomonas vaginalis CAMK family protein kinase 0.0293 0.2217 0.885
Echinococcus multilocularis rho associated protein kinase 0.0352 0.2788 0.3379
Schistosoma mansoni serine/threonine protein kinase 0.0514 0.4366 0.5774
Echinococcus granulosus epidermal growth factor receptor 0.0659 0.5775 0.5722
Loa Loa (eye worm) hypothetical protein 0.0153 0.0848 0.0906
Brugia malayi Protein kinase domain containing protein 0.01 0.0341 0.0364
Plasmodium falciparum serine/threonine protein kinase 0.0093 0.0272 0.0277
Echinococcus granulosus protein kinase c iota type 0.0322 0.2493 0.2399
Echinococcus multilocularis casein kinase I delta 0.0121 0.0537 0.064
Brugia malayi Protein kinase domain containing protein 0.0231 0.1607 0.1715
Echinococcus granulosus mitogen activated protein kinase 3 0.0094 0.0278 0.0156
Echinococcus multilocularis casein kinase I alpha 0.0121 0.0537 0.064
Onchocerca volvulus 0.0312 0.2401 0.254
Schistosoma mansoni kinase 0.0313 0.2409 0.3179
Schistosoma mansoni serine/threonine protein kinase 0.0159 0.0914 0.1196
Echinococcus granulosus tyrosine protein kinase Src64B 0.0246 0.176 0.1657
Loa Loa (eye worm) hypothetical protein 0.0095 0.0289 0.0309
Echinococcus granulosus protein kinase C gamma type 0.0224 0.1542 0.1436
Entamoeba histolytica protein kinase, putative 0.0231 0.1607 0.4725
Loa Loa (eye worm) hypothetical protein 0.014 0.0725 0.0774
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.018 0.1117 0.1006
Trichomonas vaginalis CMGC family protein kinase 0.0112 0.0448 0.1538
Onchocerca volvulus Tyrosine kinase homolog 0.0416 0.3408 0.3618
Echinococcus granulosus tyrosine kinase 0.0206 0.1371 0.1263
Schistosoma mansoni serine/threonine protein kinase 0.018 0.1113 0.1461
Loa Loa (eye worm) hypothetical protein 0.0099 0.0328 0.035
Brugia malayi cell division control protein 2 homolog 0.0132 0.0643 0.0686
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.011 0.0433 0.0313
Plasmodium vivax serine/threonine kinase-1, putative 0.0169 0.1005 0.9683
Schistosoma mansoni serine/threonine protein kinase 0.0426 0.3506 0.4633
Schistosoma mansoni protein kinase 0.0397 0.322 0.4255
Echinococcus multilocularis tyrosine protein kinase shark 0.0341 0.2677 0.3244
Echinococcus granulosus casein kinase I alpha 0.0121 0.0537 0.0419
Echinococcus granulosus insulin receptor 0.0485 0.4085 0.4011
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0231 0.1607 0.6351
Entamoeba histolytica protein kinase, putative 0.01 0.0335 0.0799
Echinococcus multilocularis serine:threonine protein kinase 0.0083 0.0172 0.0196
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0119 0.0525 0.1686
Echinococcus granulosus MAP kinase activated protein kinase 2 0.0426 0.3506 0.3424
Trichomonas vaginalis STE family protein kinase 0.015 0.0823 0.3086
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.0119 0.0525 0.0406
Entamoeba histolytica PH domain containing protein kinase, putative 0.0135 0.0676 0.185
Echinococcus granulosus [G-protein-coupledreceptor] kinase 0.0163 0.0953 0.0839
Echinococcus granulosus tyrosine protein kinase Srms 0.0548 0.4695 0.4629
Schistosoma mansoni serine/threonine protein kinase 0.0125 0.0583 0.0758
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0153 0.0852 0.3158
Trypanosoma cruzi cdc2-related kinase 3 0.0132 0.0643 0.2214
Leishmania major protein kinase A catalytic subunit 0.0125 0.0583 0.148
Loa Loa (eye worm) hypothetical protein 0.0129 0.0618 0.066
Loa Loa (eye worm) hypothetical protein 0.0382 0.3074 0.3281
Onchocerca volvulus 0.0215 0.1455 0.1527
Entamoeba histolytica protein kinase, putative 0.018 0.1117 0.3214
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0188 0.1189 0.1269
Trichomonas vaginalis CMGC family protein kinase 0.01 0.0341 0.1093
Schistosoma mansoni serine/threonine protein kinase 0.0122 0.055 0.0715
Brugia malayi Protein kinase domain containing protein 0.0102 0.036 0.0384
Echinococcus multilocularis 0.0168 0.1 0.1203
Loa Loa (eye worm) TK/FAK protein kinase 0.0852 0.7645 0.8161
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0125 0.0583 0.0696
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0094 0.0278 0.0029
Entamoeba histolytica serine/threonine protein kinase, putative 0.0293 0.2217 0.6612
Schistosoma mansoni serine/threonine protein kinase 0.0129 0.0616 0.0802
Brugia malayi Serine/threonine-protein kinase SULU 0.0242 0.1718 0.1833
Echinococcus multilocularis rac serine:threonine kinase 0.0182 0.1129 0.136
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0246 0.176 0.2129
Trichomonas vaginalis AGC family protein kinase 0.0322 0.2496 1
Trypanosoma brucei STE20-like serine/threonine-protein kinase 1, putative 0.0095 0.0288 0.0073
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0153 0.0848 0.1019
Loa Loa (eye worm) hypothetical protein 0.0215 0.1455 0.1553
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0293 0.2217 0.9257
Echinococcus granulosus serine:threonine protein kinase N2 0.0139 0.0711 0.0595
Brugia malayi Protein kinase domain containing protein 0.0112 0.0457 0.0488
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0497 0.4197 0.4125
Trypanosoma brucei protein kinase, putative 0.0142 0.0745 0.213
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0245 0.1749 0.1867
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.01 0.0337 0.036
Loa Loa (eye worm) hypothetical protein 0.0153 0.0848 0.0906
Echinococcus multilocularis NCK adaptor protein 0.0101 0.0346 0.0407
Echinococcus granulosus casein kinase I gamma 0.0232 0.1624 0.1519
Trichomonas vaginalis CAMK family protein kinase 0.0293 0.2217 0.885
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0097 0.0306 0.071
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0153 0.0848 0.0733
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0097 0.0306 0.0327
Trichomonas vaginalis CAMK family protein kinase 0.014 0.0721 0.2667
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0177 0.1086 0.1159
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0287 0.2155 0.23
Entamoeba histolytica protein kinase , putative 0.01 0.0335 0.0799
Plasmodium vivax tyrosine kinase-like protein, putative 0.0091 0.025 0.1964
Schistosoma mansoni protein kinase C mu 0.0245 0.1749 0.2304
Loa Loa (eye worm) hypothetical protein 0.01 0.0337 0.036
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0148 0.0807 0.0969
Loa Loa (eye worm) STE/STE20/SLK protein kinase 0.0211 0.1412 0.1507
Onchocerca volvulus Serine\/threonine kinase homolog 0.018 0.1113 0.1161
Echinococcus multilocularis serine:threonine protein kinase Chk2 0.008 0.0144 0.0162
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0153 0.0848 0.0733
Giardia lamblia Kinase, NEK 0.015 0.0823 0.2834
Echinococcus multilocularis activated cdc42 kinase 1 0.0233 0.1627 0.1967
Onchocerca volvulus 0.0112 0.0457 0.0458
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0153 0.0852 0.2612
Entamoeba histolytica protein kinase, putative 0.0142 0.0745 0.2066
Schistosoma mansoni serine/threonine protein kinase 0.0293 0.2217 0.2925
Brugia malayi Immunoglobulin I-set domain containing protein 0.0111 0.0441 0.047
Trichomonas vaginalis CMGC family protein kinase 0.0153 0.0852 0.3208
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0497 0.4197 0.5095
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0132 0.0643 0.1766
Entamoeba histolytica protein kinase, putative 0.0231 0.1607 0.4725
Loa Loa (eye worm) TK/EGFR protein kinase 0.0659 0.5775 0.6164
Echinococcus multilocularis casein kinase ii subunit alpha 0.0112 0.0448 0.0532
Echinococcus granulosus tyrosine protein kinase Fyn 0.0246 0.176 0.1657
Echinococcus multilocularis serine:threonine protein kinase N2 0.0319 0.2465 0.2987
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0095 0.0288 0.0617
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0153 0.0848 0.2779
Schistosoma mansoni protein kinase 0.0627 0.5465 0.723
Brugia malayi Protein kinase domain containing protein 0.0232 0.1624 0.1734
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.031 0.2373 1
Entamoeba histolytica protein kinase, putative 0.0092 0.0255 0.0551
Schistosoma mansoni serine/threonine protein kinase 0.01 0.0335 0.043
Trypanosoma cruzi mitogen-activated protein kinase kinase 5 0.0198 0.1293 0.5138
Brugia malayi Dual specificity mitogen-activated protein kinase kinase mek-2 0.0198 0.1293 0.138
Trypanosoma brucei Casein kinase II 0.0112 0.0448 0.0795
Trichomonas vaginalis CAMK family protein kinase 0.0128 0.0604 0.2181
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0438 0.3619 0.3539
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0125 0.0583 0.5366
Trypanosoma cruzi aurora B kinase, putative 0.01 0.0335 0.0831
Brugia malayi Protein kinase domain containing protein 0.0233 0.1627 0.1736
Trichomonas vaginalis STE family protein kinase 0.0096 0.0302 0.0932
Giardia lamblia Kinase, CMGC DYRK 0.0153 0.0852 0.2985
Echinococcus multilocularis dual specificity 0.0153 0.0852 0.1024
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0125 0.0583 0.1399
Loa Loa (eye worm) TK protein kinase 0.038 0.3055 0.3261
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0068 0.0026 0.0027
Schistosoma mansoni tyrosine kinase 0.0401 0.3268 0.4317
Schistosoma mansoni serine/threonine protein kinase 0.0116 0.0492 0.0637
Trichomonas vaginalis CAMK family protein kinase 0.01 0.0337 0.1078
Echinococcus multilocularis STE20 serine:threonine protein kinase 0.0533 0.4547 0.5521
Echinococcus granulosus N chimaerin 0.011 0.0433 0.0313
Loa Loa (eye worm) hypothetical protein 0.0111 0.0441 0.047
Echinococcus granulosus protein kinase 0.0168 0.1 0.0887
Toxoplasma gondii AGC kinase 0.0125 0.0583 0.1546
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.01 0.0337 0.0312
Schistosoma mansoni serine/threonine protein kinase 0.0153 0.0848 0.111
Trichomonas vaginalis CMGC family protein kinase 0.0153 0.0852 0.3208
Echinococcus granulosus cyclin dependent kinase 9 0.0088 0.0219 0.0097
Brugia malayi Protein kinase domain containing protein 0.0605 0.5247 0.5601
Schistosoma mansoni vam6/vps39 related 0.0119 0.0525 0.0682
Schistosoma mansoni vesicular amine transporter 0.0099 0.0328 0.042
Schistosoma mansoni serine/threonine protein kinase 0.0242 0.1718 0.2262
Schistosoma mansoni tyrosine kinase 0.0089 0.0227 0.0286
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.0168 0.1 0.1067
Onchocerca volvulus 0.0112 0.0457 0.0458
Schistosoma mansoni serine/threonine protein kinase 0.01 0.0337 0.0432
Trichomonas vaginalis CMGC family protein kinase 0.0094 0.0278 0.0834
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.01 0.0337 0.0839
Schistosoma mansoni protein kinase 0.0096 0.0302 0.0385
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0293 0.2217 0.212
Entamoeba histolytica protein kinase, putative 0.0322 0.2496 0.7471
Entamoeba histolytica protein kinase 2, putative 0.0172 0.1036 0.2963
Schistosoma mansoni serine/threonine protein kinase 0.0264 0.193 0.2543
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0159 0.0914 0.08
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0163 0.0953 0.1017
Brugia malayi Protein kinase domain containing protein 0.0397 0.322 0.3437
Brugia malayi P38 map kinase family protein 2 0.031 0.2373 0.2533
Schistosoma mansoni tyrosine kinase 0.0485 0.4085 0.54
Loa Loa (eye worm) STE/STE7/MEK1 protein kinase 0.0198 0.1293 0.138
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0267 0.1962 0.2374
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0267 0.1962 0.1861
Echinococcus granulosus serine:threonine protein kinase Chk2 0.008 0.0144 0.0021
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0142 0.0745 0.0629
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0096 0.0302 0.018
Brugia malayi serine/threonine protein kinase 6 0.01 0.0335 0.0358
Echinococcus granulosus tyrosine protein kinase HCK 0.0149 0.0815 0.07
Schistosoma mansoni serine/threonine protein kinase 0.0088 0.0219 0.0276
Brugia malayi intracellular kinase 0.0142 0.0745 0.0795
Echinococcus granulosus activated cdc42 kinase 1 0.0233 0.1627 0.1522
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0094 0.0278 0.0031
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0095 0.0288 0.0617
Trypanosoma cruzi Protein kinase B 0.0182 0.1129 0.4401
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0142 0.0745 0.2254
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0169 0.1005 0.1073
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0334 0.2613 0.3167
Schistosoma mansoni hypothetical protein 0.0119 0.0525 0.0682
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0177 0.1086 0.1159
Schistosoma mansoni protein kinase 0.0168 0.1 0.1311
Brugia malayi Protein kinase domain containing protein 0.0169 0.1005 0.1073
Loa Loa (eye worm) TK protein kinase 0.0206 0.1371 0.1464
Trichomonas vaginalis CMGC family protein kinase 0.0169 0.1005 0.3838
Echinococcus granulosus serine:threonine protein kinase 12 B 0.01 0.0335 0.0214
Schistosoma mansoni serine/threonine protein kinase 0.0121 0.0537 0.0698
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.011 0.0433 0.056
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0097 0.0308 0.0329
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.0119 0.0525 0.0626
Trypanosoma cruzi casein kinase, putative 0.0121 0.0537 0.174
Giardia lamblia Kinase, AGC PKA 0.0172 0.1036 0.3928
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0132 0.0643 0.0686
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0381 0.3073 0.328
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.01 0.0335 0.0799
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0261 0.1904 0.2304
Brugia malayi Sex muscle abnormal protein 5 0.0097 0.0308 0.0329
Loa Loa (eye worm) camk/dcamkl protein kinase 0.0166 0.0976 0.1041
Brugia malayi Temporarily assigned gene name protein 59 0.0138 0.0705 0.0752
Echinococcus granulosus calcium activated potassium channel 0.0116 0.0492 0.0373
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0112 0.0448 0.3994
Trichomonas vaginalis CAMK family protein kinase 0.0083 0.0172 0.0396
Brugia malayi Hr1 repeat family protein 0.0319 0.2465 0.2631
Loa Loa (eye worm) hypothetical protein 0.0111 0.0441 0.047
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0094 0.0278 0.0031
Giardia lamblia Kinase, STE STE20 0.0095 0.0288 0.0083
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0169 0.1005 0.3297
Schistosoma mansoni ephrin receptor 0.0067 0.0014 0.0003
Trichomonas vaginalis CMGC family protein kinase 0.0094 0.0278 0.0834
Echinococcus granulosus tyrosine protein kinase Lyn 0.0286 0.2147 0.2049
Schistosoma mansoni serine/threonine protein kinase 0.0078 0.0124 0.0149
Schistosoma mansoni tyrosine kinase 0.0659 0.5775 0.7641
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0381 0.3073 0.328
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0112 0.0457 0.1175
Loa Loa (eye worm) AUR protein kinase 0.01 0.0335 0.0358
Schistosoma mansoni serine/threonine protein kinase 0.0159 0.0914 0.1196
Loa Loa (eye worm) hypothetical protein 0.0097 0.0308 0.0329
Echinococcus multilocularis 0.0129 0.0618 0.0739
Echinococcus granulosus serine:threonine protein kinase 0.0083 0.0172 0.0049
Schistosoma mansoni tyrosine kinase 0.0437 0.3611 0.4772
Schistosoma mansoni serine/threonine protein kinase 0.0381 0.3073 0.4059
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0203 0.1339 0.1429
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0261 0.1904 0.1803
Echinococcus granulosus serine:threonine kinase SAD 1 0.01 0.0337 0.0216
Brugia malayi STE20-like kinase MST 0.0279 0.2078 0.2218
Schistosoma mansoni titin 0.0078 0.0124 0.0149
Trypanosoma cruzi casein kinase, putative 0.0121 0.0537 0.174
Trichomonas vaginalis AGC family protein kinase 0.01 0.0335 0.107
Brugia malayi Protein kinase domain containing protein 0.0105 0.0387 0.0413
Trypanosoma cruzi SNF1-related protein kinases, putative 0.01 0.0337 0.0839
Trichomonas vaginalis CMGC family protein kinase 0.0132 0.0643 0.2341
Loa Loa (eye worm) hypothetical protein 0.0382 0.3074 0.3281
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0381 0.3073 0.2986
Echinococcus multilocularis raf serine:threonine protein kinase 0.0108 0.0415 0.0491
Trichomonas vaginalis AGC family protein kinase 0.01 0.0337 0.1077
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0169 0.1005 0.3843
Entamoeba histolytica protein kinase, putative 0.01 0.0335 0.0799
Schistosoma mansoni hypothetical protein 0.0076 0.0105 0.0124
Loa Loa (eye worm) TK protein kinase 0.0149 0.0815 0.087
Echinococcus multilocularis G protein coupled receptor kinase 6 0.0163 0.0953 0.1146
Trichomonas vaginalis CAMK family protein kinase 0.0302 0.23 0.919
Plasmodium falciparum protein serine/threonine kinase-1 0.0169 0.1005 0.9605
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0153 0.0848 0.1019
Schistosoma mansoni protein kinase 0.0095 0.0288 0.0367
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0152 0.0846 0.1107
Loa Loa (eye worm) CMGC/SRPK protein kinase 0.0093 0.0272 0.029
Schistosoma mansoni serine/threonine-protein kinase 0.0182 0.1129 0.1482
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0095 0.0288 0.0617
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0082 0.0162 0.0183
Echinococcus granulosus serine:threonine protein kinase 0.0083 0.0172 0.0049
Echinococcus granulosus defective proboscis extension response 0.0099 0.0328 0.0207
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0118 0.051 0.0391
Schistosoma mansoni serine/threonine protein kinase 0.0169 0.1005 0.1317
Schistosoma mansoni serine/threonine protein kinase 0.0264 0.193 0.2543
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0219 0.1495 0.1595
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.0279 0.2078 0.2218
Brugia malayi Protein kinase domain containing protein 0.0204 0.1345 0.1436
Echinococcus granulosus serine:threonine protein kinase 3 0.0279 0.2078 0.1978
Trichomonas vaginalis CAMK family protein kinase 0.01 0.0337 0.1078
Echinococcus granulosus STE20 serine:threonine protein kinase 0.0533 0.4547 0.4479
Trichomonas vaginalis STE family protein kinase 0.0095 0.0288 0.0874
Brugia malayi Variant SH3 domain containing protein 0.0068 0.0026 0.0027
Loa Loa (eye worm) hypothetical protein 0.0092 0.0256 0.0273
Entamoeba histolytica protein kinase domain containing protein 0.0153 0.0852 0.2396
Echinococcus multilocularis protein kinase c epsilon type 0.0235 0.1644 0.1987
Trypanosoma brucei casein kinase I, isoform 2 0.0121 0.0537 0.1195
Echinococcus granulosus protein kinase shaggy 0.0142 0.0745 0.0629
Schistosoma mansoni hypothetical protein 0.0076 0.0105 0.0124
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0096 0.0302 0.0354
Schistosoma mansoni serine/threonine protein kinase 0.0092 0.0255 0.0323
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0245 0.1749 0.1867
Loa Loa (eye worm) TK/ABL protein kinase 0.0334 0.2613 0.2789
Trichomonas vaginalis CMGC family protein kinase 0.0112 0.0448 0.1538
Loa Loa (eye worm) AGC/NDR protein kinase 0.018 0.1117 0.1192
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0246 0.176 0.1657
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0094 0.0278 0.0574
Trypanosoma brucei SNF1-related protein kinases, putative 0.01 0.0337 0.0294
Brugia malayi Kinase associated domain 1 family protein 0.0076 0.0105 0.0112
Echinococcus multilocularis serine threonine protein kinase 0.0224 0.1542 0.1864
Echinococcus granulosus serine:threonine protein kinase mig 15 0.0248 0.1775 0.1671
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0095 0.0288 0.0176
Echinococcus granulosus TGF beta receptor type 1 0.0117 0.0497 0.0377
Loa Loa (eye worm) TK/ROR protein kinase 0.0082 0.0162 0.0173
Brugia malayi phosphoinositide-dependent protein kinase I 0.0092 0.0255 0.0272
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0438 0.3619 0.4391
Echinococcus multilocularis nervana 2 0.0132 0.0649 0.0777
Schistosoma mansoni serine/threonine protein kinase 0.0352 0.2788 0.3681
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0264 0.193 0.1828
Schistosoma mansoni serine/threonine protein kinase 0.0094 0.0278 0.0354
Brugia malayi Protein kinase domain containing protein 0.0071 0.0051 0.0054
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0206 0.1371 0.1656
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0124 0.0565 0.0447
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0159 0.0912 0.1097
Schistosoma mansoni serine/threonine protein kinase 0.0277 0.2056 0.2711
Brugia malayi serine/threonine-protein kinase PAK 7 0.0253 0.182 0.1943
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0096 0.0302 0.0354
Onchocerca volvulus 0.0112 0.0457 0.0458
Schistosoma mansoni tyrosine kinase 0.0381 0.3073 0.406
Trypanosoma brucei cdc2-related kinase 3 0.0132 0.0643 0.1669
Loa Loa (eye worm) AGC/PKA protein kinase 0.0125 0.0583 0.0622
Brugia malayi Protein kinase domain containing protein 0.0092 0.0255 0.0272
Trichomonas vaginalis CAMK family protein kinase 0.0293 0.2217 0.885
Brugia malayi protein kinase C3,putative 0.0181 0.1126 0.1202
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0132 0.0643 0.1825
Trypanosoma cruzi cdc2-related kinase 1 0.0132 0.0643 0.2214
Schistosoma mansoni serine/threonine protein kinase 0.0093 0.0272 0.0345
Entamoeba histolytica protein kinase, putative 0.0083 0.0169 0.0287
Plasmodium vivax calcium-dependent protein kinase, putative 0.0153 0.0848 0.8079
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.0153 0.0852 0.2799
Trypanosoma brucei rac serine-threonine kinase, putative 0.0322 0.2496 1
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0092 0.0255 0.0296
Echinococcus multilocularis growth factor receptor bound protein 2 0.0097 0.0308 0.0362
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0246 0.176 0.2129
Plasmodium falciparum glycogen synthase kinase 3 0.0142 0.0745 0.6303
Schistosoma mansoni protein kinase 0.0627 0.5465 0.723
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0235 0.1644 0.1755
Loa Loa (eye worm) TK/FER protein kinase 0.0112 0.0457 0.0488
Trypanosoma brucei protein kinase, putative 0.0095 0.0288 0.0072
Echinococcus granulosus mitogen activated protein kinase 0.0094 0.0278 0.0156
Schistosoma mansoni cell adhesion molecule 0.013 0.0623 0.0811
Echinococcus granulosus c-Jun N-terminal kinases 0.0287 0.2155 0.2056
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0125 0.0583 0.0622
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.031 0.2373 1
Loa Loa (eye worm) hypothetical protein 0.0067 0.0013 0.0013
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0086 0.0196 0.0073
Echinococcus multilocularis homeodomain interacting protein kinase 3 0.0221 0.1514 0.1829
Echinococcus granulosus epidermal growth factor receptor 0.0437 0.3611 0.3531
Trypanosoma brucei cdc2-related kinase 1 0.0132 0.0643 0.1669
Echinococcus multilocularis protein kinase shaggy 0.0142 0.0745 0.0894
Trichomonas vaginalis AGC family protein kinase 0.01 0.0335 0.107
Schistosoma mansoni growth factor receptor-bound protein 0.0097 0.0308 0.0394
Brugia malayi serine/threonine-protein kinase plk-2 0.0293 0.2217 0.2367
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0437 0.3611 0.4382
Echinococcus granulosus cGMP dependent protein kinase 0.0148 0.0807 0.0692
Loa Loa (eye worm) hypothetical protein 0.0248 0.1775 0.1894
Loa Loa (eye worm) AUR protein kinase 0.01 0.0335 0.0358
Trichomonas vaginalis CMGC family protein kinase 0.0094 0.0278 0.0834
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.0219 0.1494 0.1805
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0507 0.4294 0.4583
Echinococcus granulosus twitchin 0.0166 0.0976 0.0862
Loa Loa (eye worm) hypothetical protein 0.0145 0.0771 0.0823
Schistosoma mansoni tyrosine kinase 0.0842 0.7554 1
Plasmodium falciparum calcium-dependent protein kinase 3 0.0153 0.0848 0.761
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.0484 0.4071 0.4345
Brugia malayi probable protein kinase 0.0288 0.2161 0.2307
Loa Loa (eye worm) TK/FER protein kinase 0.0437 0.3611 0.3854
Onchocerca volvulus 0.0352 0.2788 0.2954
Schistosoma mansoni tyrosine kinase 0.0381 0.3073 0.406
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.0253 0.182 0.1943
Echinococcus granulosus tyrosine kinase 0.0112 0.0457 0.0337
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0142 0.0745 0.2676
Loa Loa (eye worm) hypothetical protein 0.0125 0.0583 0.0622
Loa Loa (eye worm) hypothetical protein 0.0068 0.0029 0.0031
Schistosoma mansoni tyrosine kinase 0.0381 0.3073 0.406
Trichomonas vaginalis STE family protein kinase 0.0198 0.1293 0.5028
Schistosoma mansoni serine/threonine protein kinase 0.0125 0.0583 0.0758
Entamoeba histolytica hypothetical protein 0.0406 0.3315 1
Echinococcus granulosus serine:threonine protein kinase TAO1 0.0242 0.1718 0.1614
Echinococcus granulosus tyrosine protein kinase Blk 0.0206 0.1371 0.1263
Schistosoma mansoni serine/threonine protein kinase 0.0148 0.0807 0.1055
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.031 0.2373 1
Echinococcus granulosus casein kinase I delta 0.0121 0.0537 0.0419
Entamoeba histolytica casein kinase, putative 0.0112 0.0448 0.1149
Trichomonas vaginalis CAMK family protein kinase 0.0128 0.0604 0.2181
Echinococcus multilocularis tyrosine protein kinase HCK 0.0149 0.0815 0.0979
Echinococcus multilocularis dual specificity 0.0231 0.1607 0.1942
Trichomonas vaginalis AGC family protein kinase 0.0322 0.2496 1
Echinococcus multilocularis casein kinase I delta 0.0121 0.0537 0.064
Echinococcus multilocularis serine:threonine kinase SAD 1 0.01 0.0337 0.0397
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0153 0.0848 0.8079
Brugia malayi Protein kinase domain containing protein 0.0209 0.1393 0.1487
Echinococcus granulosus cyclin dependent kinase 19 0.018 0.1113 0.1002
Entamoeba histolytica protein kinase domain containing protein 0.0112 0.0448 0.1149
Echinococcus multilocularis tyrosine kinase 0.0112 0.0457 0.0543
Echinococcus granulosus phosphorylase kinase gamma subunit 0.018 0.1113 0.1002
Loa Loa (eye worm) CMGC/DYRK/HIPK protein kinase 0.0221 0.1514 0.1616
Leishmania major protein kinase A catalytic subunit isoform 1 0.0125 0.0583 0.148
Trichomonas vaginalis CAMK family protein kinase 0.014 0.0721 0.2667
Leishmania major protein kinase, putative 0.0153 0.0848 0.2743
Schistosoma mansoni serine/threonine protein kinase 0.0132 0.0643 0.0837
Loa Loa (eye worm) hypothetical protein 0.035 0.2763 0.2949
Loa Loa (eye worm) TK/INSR protein kinase 0.0485 0.4085 0.436
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0627 0.5465 0.6638
Echinococcus granulosus leucine rich repeat serine:threonine protein 0.0103 0.0361 0.024
Echinococcus multilocularis protein KINase family member (kin 25) 0.0124 0.0565 0.0675
Echinococcus multilocularis mitogen activated protein kinase 3 0.0094 0.0278 0.0325
Loa Loa (eye worm) hypothetical protein 0.0076 0.0105 0.0112
Giardia lamblia Kinase, AGC AKT 0.013 0.0625 0.1815
Loa Loa (eye worm) CMGC/CDK/CDK7 protein kinase 0.0122 0.055 0.0588
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0203 0.1339 0.1616
Giardia lamblia Kinase, PLK 0.0293 0.2217 1
Leishmania major protein kinase, putative 0.0095 0.0288 0.0076
Loa Loa (eye worm) RhoGAP domain-containing protein 0.011 0.0433 0.0463
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.027 0.1991 0.1891
Entamoeba histolytica cell division protein kinase 2, putative 0.0132 0.0643 0.1749
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0231 0.1607 0.655
Loa Loa (eye worm) casein kinase 0.0193 0.1238 0.1321
Echinococcus multilocularis casein kinase I alpha 0.0121 0.0537 0.064
Brugia malayi hypothetical protein 0.0112 0.0457 0.0488
Echinococcus multilocularis calcium:calmodulin dependent protein kinase I 0.008 0.0144 0.0162
Loa Loa (eye worm) thyroid receptor interactor 0.0121 0.0541 0.0578
Brugia malayi protein unc-22 0.0078 0.0124 0.0132
Brugia malayi hypothetical protein 0.0119 0.0525 0.0561
Schistosoma mansoni nephrin 0.0138 0.0702 0.0915
Echinococcus multilocularis cyclin dependent kinase 1 0.0132 0.0643 0.0769
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.018 0.1117 0.1346
Giardia lamblia Kinase, CMGC CDK 0.0132 0.0643 0.1907
Echinococcus multilocularis tyrosine protein kinase Abl 0.0237 0.167 0.2019
Onchocerca volvulus 0.0112 0.0457 0.0458
Giardia lamblia Kinase, CMGC CLK 0.0169 0.1005 0.3769
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0132 0.0649 0.0532
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0095 0.0288 0.0617
Schistosoma mansoni serine/threonine protein kinase 0.0219 0.1495 0.1967
Schistosoma mansoni serine/threonine protein kinase 0.018 0.1113 0.1461
Loa Loa (eye worm) hypothetical protein 0.0068 0.0028 0.003
Echinococcus granulosus dual specificity 0.0153 0.0852 0.0738
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0125 0.0583 0.0465
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0092 0.0255 0.0272
Trichomonas vaginalis CAMK family protein kinase 0.0204 0.1345 0.5246
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.015 0.0823 0.7823
Echinococcus multilocularis casein kinase i 0.0121 0.0537 0.064
Trichomonas vaginalis CAMK family protein kinase 0.01 0.0337 0.1078
Giardia lamblia Kinase, AGC PKA 0.0125 0.0583 0.1599
Entamoeba histolytica protein kinase domain containing protein 0.0095 0.0288 0.0652
Trichomonas vaginalis AGC family protein kinase 0.0322 0.2496 1
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.011 0.0433 0.056
Loa Loa (eye worm) hypothetical protein 0.0068 0.0028 0.003
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0132 0.0643 0.1766
Schistosoma mansoni protein kinase 0.0211 0.1412 0.1857
Entamoeba histolytica protein kinase, putative 0.0093 0.0272 0.0603
Echinococcus multilocularis dual specificity protein kinase clk2 0.0169 0.1005 0.121
Brugia malayi Homeodomain interacting protein kinase protein 1 0.0221 0.1514 0.1616
Loa Loa (eye worm) CMGC/CDK/CDK9 protein kinase 0.0088 0.0219 0.0234
Loa Loa (eye worm) TK/FER protein kinase 0.0112 0.0457 0.0488
Brugia malayi Protein kinase domain containing protein 0.0484 0.4071 0.4345
Echinococcus multilocularis transfer RNA-Thr 0.0233 0.1627 0.1967
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0153 0.0848 0.0905
Toxoplasma gondii CMGC kinase, CK2 family 0.0112 0.0448 0.0922
Schistosoma mansoni protein kinase 0.0121 0.0537 0.0698
Schistosoma mansoni protein kinase 0.0117 0.0497 0.0644
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0264 0.193 0.2335
Onchocerca volvulus 0.0112 0.0457 0.0458
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0163 0.0953 0.1017
Echinococcus granulosus activated cdc42 kinase 1 0.0233 0.1627 0.1522
Echinococcus multilocularis cyclin dependent kinase 5 0.0132 0.0643 0.0769
Brugia malayi Fibronectin type III domain containing protein 0.0111 0.0441 0.047
Brugia malayi Immunoglobulin I-set domain containing protein 0.0507 0.4294 0.4583
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0125 0.0583 0.1399
Echinococcus multilocularis PAK box P21 Rho binding 0.0073 0.0076 0.0079
Schistosoma mansoni serine/threonine protein kinase 0.0116 0.0492 0.0637
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0099 0.0328 0.042
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0159 0.0912 0.0798
Schistosoma mansoni serine/threonine protein kinase 0.018 0.1117 0.1466
Trichomonas vaginalis AGC family protein kinase 0.0189 0.1199 0.4642
Schistosoma mansoni serine/threonine protein kinase 0.0125 0.0583 0.0758
Echinococcus multilocularis roundabout 2 0.0156 0.0884 0.1062
Trypanosoma cruzi cdc2-related kinase 1 0.0132 0.0643 0.2214
Entamoeba histolytica PH domain containing protein kinase, putative 0.0182 0.1129 0.325
Entamoeba histolytica hypothetical protein 0.0231 0.1607 0.4725
Echinococcus multilocularis protein tyrosine kinase 0.0842 0.7554 0.9181
Brugia malayi Variant SH3 domain containing protein 0.0097 0.0308 0.0329
Leishmania major protein kinase A catalytic subunit isoform 2 0.0125 0.0583 0.148
Schistosoma mansoni serine/threonine protein kinase 0.01 0.0341 0.0437
Echinococcus granulosus calcium dependent protein kinase 0.0113 0.0461 0.0342
Trichomonas vaginalis STE family protein kinase 0.0198 0.1293 0.5028
Schistosoma mansoni protein kinase 0.0627 0.5465 0.723
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0095 0.0288 0.0072
Echinococcus granulosus tyrosine protein kinase Src42A 0.0246 0.176 0.1657
Onchocerca volvulus 0.0119 0.0525 0.0531
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0169 0.1005 0.3297
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0172 0.1036 1
Trichomonas vaginalis CMGC family protein kinase 0.0142 0.0745 0.2765
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.031 0.2373 0.2533
Onchocerca volvulus 0.0082 0.016 0.014
Giardia lamblia Kinase, CMGC CDK 0.0132 0.0643 0.1907
Trichomonas vaginalis AGC family protein kinase 0.018 0.1117 0.4302
Echinococcus multilocularis serine:threonine protein kinase N2 0.0139 0.0711 0.0852
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.0426 0.3506 0.3742
Schistosoma mansoni serine/threonine protein kinase 0.0132 0.0643 0.0837
Echinococcus granulosus casein kinase I alpha 0.0121 0.0537 0.0419
Giardia lamblia Kinase, STE STE20 0.0198 0.1293 0.5248
Schistosoma mansoni protein kinase 0.0288 0.2161 0.2851
Echinococcus multilocularis serine:threonine protein kinase 3 0.0279 0.2078 0.2515
Entamoeba histolytica protein kinase domain containing protein 0.0142 0.0745 0.2066
Trichomonas vaginalis CAMK family protein kinase 0.01 0.0337 0.1078
Brugia malayi Protein kinase domain containing protein 0.0112 0.0457 0.0488
Echinococcus granulosus dual specificity 0.0153 0.0852 0.0738
Leishmania major mitogen-activated protein kinase kinase 5, putative;with=GeneDB:LmxM36.0860 0.0198 0.1293 0.4858
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0119 0.0525 0.0682
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0246 0.176 0.2129
Trypanosoma brucei aurora B kinase 0.01 0.0335 0.0286
Trypanosoma cruzi serine/arginine-rich protein specific kinase SRPK, putative 0.0093 0.0272 0.0545
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0313 0.2403 0.2565
Trypanosoma cruzi casein kinase, putative 0.0121 0.0537 0.174
Echinococcus granulosus nervana 2 0.0132 0.0649 0.0532
Echinococcus granulosus casein kinase i 0.0121 0.0537 0.0419
Loa Loa (eye worm) hypothetical protein 0.0646 0.5645 0.6026
Plasmodium falciparum serine/threonine protein kinase KIN 0.01 0.0337 0.111
Toxoplasma gondii histone kinase SNF1, putative 0.01 0.0337 0.0405
Echinococcus granulosus cyclin dependent kinase 9 0.0096 0.0302 0.018
Entamoeba histolytica PH domain containing protein kinase, putative 0.0182 0.1129 0.325
Onchocerca volvulus 0.0153 0.0848 0.0877
Brugia malayi Protein kinase c protein 2 0.0136 0.0689 0.0736
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.0242 0.1718 0.1833
Trypanosoma cruzi casein kinase, putative 0.0121 0.0537 0.174
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0159 0.0913 0.1098
Brugia malayi Stress-activated protein kinase jnk-1 0.0287 0.2155 0.23
Brugia malayi ribosomal protein S6 kinase alpha 3 0.013 0.0625 0.0667
Entamoeba histolytica protein kinase, putative 0.0083 0.0169 0.0287
Brugia malayi Protein kinase domain containing protein 0.0211 0.1412 0.1507
Loa Loa (eye worm) IKK protein kinase 0.1029 0.9368 1
Echinococcus granulosus cGMP dependent protein kinase 1 0.0148 0.0807 0.0692
Plasmodium falciparum serine/threonine protein kinase, putative 0.01 0.0335 0.1086
Echinococcus granulosus serine/threonine protein kinase 0.0182 0.1129 0.1018
Schistosoma mansoni tyrosine kinase 0.0152 0.0846 0.1107
Echinococcus granulosus cyclin dependent kinase 7 0.0122 0.055 0.0432
Loa Loa (eye worm) hypothetical protein 0.0297 0.2249 0.2401
Trichomonas vaginalis CAMK family protein kinase 0.01 0.0337 0.1078
Loa Loa (eye worm) SRC-1 0.0246 0.176 0.1879
Trypanosoma cruzi casein kinase, putative 0.0121 0.0537 0.174
Echinococcus granulosus cyclin dependent kinase 1 0.0132 0.0643 0.0525
Entamoeba histolytica protein kinase domain containing protein 0.0231 0.1607 0.4725
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0099 0.0328 0.042
Brugia malayi cyclin-dependent kinase 7 homolog 0.0131 0.0633 0.0675
Brugia malayi Variant SH3 domain containing protein 0.0097 0.0308 0.0329
Loa Loa (eye worm) AGC/PKG protein kinase 0.0148 0.0807 0.0861
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.0153 0.0852 0.091
Echinococcus multilocularis phosphorylase kinase gamma subunit 0.018 0.1113 0.1342
Trichomonas vaginalis AGC family protein kinase 0.0092 0.0255 0.0737
Plasmodium vivax serine/threonine protein kinase, putative 0.0093 0.0272 0.2186
Brugia malayi casein kinase 1, delta 0.0121 0.0537 0.0573
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0094 0.0278 0.0131
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0246 0.176 0.1657
Brugia malayi Tyrosine-protein kinase abl-1 0.0137 0.0695 0.0742
Echinococcus granulosus cGMP dependent protein kinase 1 0.0148 0.0807 0.0692
Onchocerca volvulus 0.0078 0.0124 0.0101
Loa Loa (eye worm) hypothetical protein 0.0153 0.0848 0.0905
Brugia malayi p70 ribosomal S6 kinase beta 0.0313 0.2403 0.2565
Loa Loa (eye worm) TKL/LRRK protein kinase 0.0102 0.036 0.0384
Onchocerca volvulus 0.0334 0.261 0.2763
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0125 0.0583 0.1944
Echinococcus multilocularis TGF beta receptor type 1 0.0117 0.0497 0.0591
Schistosoma mansoni serine/threonine protein kinase 0.027 0.1991 0.2625
Echinococcus granulosus activin receptor type 0.0487 0.4099 0.4025
Giardia lamblia Kinase, CAMK CAMKL 0.0109 0.0419 0.0759
Brugia malayi hypothetical protein 0.0242 0.1718 0.1833
Schistosoma mansoni serine/threonine protein kinase 0.0232 0.1624 0.2139
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.018 0.1117 0.1346
Echinococcus multilocularis cyclin dependent kinase 9 0.0088 0.0219 0.0253
Echinococcus granulosus neuroglian 0.0126 0.0589 0.0471
Entamoeba histolytica protein kinase, putative 0.0093 0.0272 0.0603
Schistosoma mansoni serine/threonine protein kinase 0.0108 0.0415 0.0535
Brugia malayi protein kinase C II. 0.0235 0.1644 0.1755
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0119 0.0525 0.0682
Schistosoma mansoni serine/threonine protein kinase 0.0169 0.1005 0.1317
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0475 0.398 0.4249
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0172 0.1036 1
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0153 0.0848 0.0733
Trichomonas vaginalis CK1 family protein kinase 0.0121 0.0537 0.1905
Leishmania major protein kinase, putative 0.0095 0.0288 0.0077
Trichomonas vaginalis CAMK family protein kinase 0.01 0.0337 0.1078
Brugia malayi Protein kinase domain containing protein 0.0112 0.0457 0.0488
Loa Loa (eye worm) hypothetical protein 0.0297 0.2249 0.2401
Loa Loa (eye worm) hypothetical protein 0.0191 0.122 0.1302
Trichomonas vaginalis STE family protein kinase 0.0198 0.1293 0.5028
Echinococcus multilocularis maternal embryonic leucine zipper kinase 0.0128 0.0604 0.0722
Trichomonas vaginalis AGC family protein kinase 0.0125 0.0583 0.2093
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0169 0.1005 0.3843
Echinococcus multilocularis death associated protein kinase 1 0.0911 0.8227 1
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0125 0.0583 0.0465
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.01 0.0337 0.0312
Echinococcus multilocularis protein kinase c iota type 0.0322 0.2493 0.302
Brugia malayi protein-tyrosine kinase 0.0206 0.1371 0.1464
Loa Loa (eye worm) hypothetical protein 0.0127 0.06 0.0641
Echinococcus granulosus serine threonine protein kinase nrc 0.0172 0.1036 0.0924
Brugia malayi map kinase activated protein kinase protein 2 0.0426 0.3506 0.3742
Echinococcus multilocularis mitogen activated protein kinase 14 0.031 0.2373 0.2875
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.011 0.0433 0.0514
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.031 0.2373 0.9451
Brugia malayi Protein kinase domain containing protein 0.0852 0.7645 0.8161
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0246 0.176 0.2129
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0142 0.0745 0.0795
Giardia lamblia Kinase, CMGC CK2 0.0112 0.0448 0.0909
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0132 0.0643 0.0686
Echinococcus multilocularis calcium dependent protein kinase 0.0113 0.0461 0.0548
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0099 0.0328 0.0386
Loa Loa (eye worm) hypothetical protein 0.0191 0.122 0.1302
Onchocerca volvulus 0.0206 0.1362 0.1427
Schistosoma mansoni nck2/grb4 0.0097 0.0308 0.0394
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0125 0.0583 0.4234
Onchocerca volvulus Serine\/threonine kinase homolog 0.0293 0.2217 0.2343
Trichomonas vaginalis AGC family protein kinase 0.019 0.121 0.4686
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0277 0.2056 0.2489
Loa Loa (eye worm) hypothetical protein 0.0119 0.0525 0.0561
Schistosoma mansoni tyrosine kinase 0.0284 0.212 0.2796
Schistosoma mansoni vav2 0.012 0.0526 0.0683
Echinococcus granulosus casein kinase I delta 0.0121 0.0537 0.0419
Loa Loa (eye worm) hypothetical protein 0.0233 0.1627 0.1736
Echinococcus multilocularis c src tyrosine kinase 0.0152 0.0846 0.1016
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0231 0.1607 0.1715
Brugia malayi Protein kinase domain containing protein 0.0132 0.0643 0.0686
Trichomonas vaginalis STE family protein kinase 0.0096 0.0302 0.0932
Brugia malayi Protein kinase domain containing protein 0.018 0.1117 0.1192
Loa Loa (eye worm) TK/FER protein kinase 0.0112 0.0457 0.0488
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0078 0.0124 0.0132
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0287 0.2155 0.2609
Trichomonas vaginalis CMGC family protein kinase 0.0112 0.0448 0.1538
Schistosoma mansoni serine/threonine protein kinase 0.01 0.0337 0.0432
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.0219 0.1494 0.1388
Entamoeba histolytica protein kinase, putative 0.0097 0.0306 0.071
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0646 0.5645 0.6026
Trichomonas vaginalis AGC family protein kinase 0.0322 0.2496 1
Trichomonas vaginalis STE family protein kinase 0.0096 0.0302 0.0932
Schistosoma mansoni serine/threonine protein kinase 0.01 0.0337 0.0432
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0094 0.0278 0.0574
Entamoeba histolytica protein kinase domain containing protein 0.0221 0.1514 0.444
Entamoeba histolytica protein kinase, putative 0.0322 0.2496 0.7471
Brugia malayi SRC-1 0.0246 0.176 0.1879
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0153 0.0848 0.2592
Echinococcus multilocularis epidermal growth factor receptor 0.0437 0.3611 0.4381
Schistosoma mansoni serine/threonine protein kinase 0.0277 0.2056 0.2711
Brugia malayi casein kinase I 0.0121 0.0537 0.0573
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0381 0.3073 0.3727
Trypanosoma brucei mitogen-activated protein kinase kinase 5 0.0198 0.1293 0.4591
Loa Loa (eye worm) AGC/PKA protein kinase 0.0125 0.0583 0.0622
Echinococcus granulosus dual specificity mitogen activated protein 0.0198 0.1293 0.1184
Schistosoma mansoni serine/threonine protein kinase 0.01 0.0337 0.0432
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0125 0.0583 0.1944
Schistosoma mansoni adapter molecule crk 0.0097 0.0308 0.0394
Brugia malayi hypothetical protein 0.0111 0.0441 0.047
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0381 0.3073 0.328
Onchocerca volvulus 0.01 0.0341 0.0334
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0293 0.2217 0.2367
Plasmodium falciparum calcium-dependent protein kinase 5 0.0153 0.0848 0.761
Trichomonas vaginalis CMGC family protein kinase 0.0112 0.0448 0.1538
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0203 0.1339 0.1231
Trichomonas vaginalis CAMK family protein kinase 0.01 0.0337 0.1078
Plasmodium falciparum casein kinase 1 0.0121 0.0537 0.3656
Loa Loa (eye worm) hypothetical protein 0.0256 0.1856 0.1981
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0159 0.0914 0.08
Onchocerca volvulus 0.0142 0.0745 0.0767
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.1011 0.92 0.982
Brugia malayi bone morphogenetic protein type 1 receptor 0.0132 0.0647 0.0691
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0119 0.0525 0.1686
Schistosoma mansoni protein kinase 0.01 0.0335 0.043
Trichomonas vaginalis CK1 family protein kinase 0.0121 0.0537 0.1905
Loa Loa (eye worm) AGC/AKT protein kinase 0.0322 0.2496 0.2664
Schistosoma mansoni serine/threonine protein kinase 0.0277 0.2059 0.2714
Schistosoma mansoni ste20-related kinase 0.0224 0.154 0.2027
Loa Loa (eye worm) hypothetical protein 0.0493 0.416 0.4441
Schistosoma mansoni serine/threonine protein kinase 0.0122 0.055 0.0715
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0153 0.0848 0.8079
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0646 0.5645 0.6026
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0092 0.0255 0.0132
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0121 0.0537 0.0573
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.027 0.1991 0.241
Echinococcus granulosus tyrosine protein kinase Fyn 0.0246 0.176 0.1657
Schistosoma mansoni serine/threonine protein kinase 0.0319 0.2465 0.3253
Loa Loa (eye worm) hypothetical protein 0.0083 0.0172 0.0184
Entamoeba histolytica protein kinase, putative 0.0149 0.0815 0.2282
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0172 0.1036 0.3983
Brugia malayi Protein kinase domain containing protein 0.018 0.1113 0.1188
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.0083 0.0172 0.0184
Echinococcus multilocularis cyclin dependent kinase 19 0.018 0.1113 0.1342
Entamoeba histolytica protein kinase, putative 0.0154 0.0861 0.2424
Brugia malayi Protein kinase domain containing protein 0.0093 0.0272 0.029
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0121 0.0537 0.0573
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0437 0.3611 0.3531
Trichomonas vaginalis AGC family protein kinase 0.01 0.0335 0.107
Echinococcus multilocularis Immunoglobulin 0.0099 0.0328 0.0386
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0206 0.1371 0.1263
Schistosoma mansoni protein kinase 0.0261 0.1904 0.2509
Toxoplasma gondii AGC kinase 0.0313 0.2403 1
Echinococcus granulosus Immunoglobulin 0.0099 0.0328 0.0207
Leishmania major protein kinase, putative 0.0169 0.1005 0.3489
Echinococcus granulosus calcium:calmodulin dependent protein kinase I 0.008 0.0144 0.002
Loa Loa (eye worm) hypothetical protein 0.0519 0.4413 0.4711
Loa Loa (eye worm) hypothetical protein 0.0124 0.0565 0.0603
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.01 0.0335 0.0394
Trichomonas vaginalis CAMK family protein kinase 0.01 0.0337 0.1078
Entamoeba histolytica protein kinase, putative 0.0096 0.0302 0.0696
Echinococcus granulosus tyrosine protein kinase 0.0312 0.2393 0.2298
Trichomonas vaginalis CMGC family protein kinase 0.01 0.0341 0.1093
Schistosoma mansoni protein kinase 0.0261 0.1904 0.2509
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.01 0.0337 0.0294
Toxoplasma gondii cell-cycle-associated protein kinase SRPK, putative 0.0093 0.0272 0.0101
Onchocerca volvulus 0.0121 0.0537 0.0544
Trichomonas vaginalis CAMK family protein kinase 0.01 0.0337 0.1078
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0169 0.1005 0.3507
Onchocerca volvulus 0.0081 0.015 0.013
Brugia malayi Variant SH3 domain containing protein 0.011 0.0433 0.0463
Echinococcus multilocularis tyrosine protein kinase Blk 0.0206 0.1371 0.1656
Brugia malayi Fes/CIP4 homology domain containing protein 0.0121 0.0541 0.0578
Echinococcus granulosus ephrin type A receptor 4 A 0.0124 0.0566 0.0448
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0139 0.0718 0.2122
Echinococcus multilocularis tyrosine protein kinase Srms 0.0206 0.1371 0.1656
Toxoplasma gondii aurora kinase 0.01 0.0335 0.0396
Trichomonas vaginalis CMGC family protein kinase 0.0153 0.0852 0.3208
Schistosoma mansoni serine/threonine protein kinase 0.0221 0.1514 0.1993
Echinococcus multilocularis aurora kinase A 0.01 0.0335 0.0394
Loa Loa (eye worm) AUR protein kinase 0.01 0.0335 0.0358
Loa Loa (eye worm) CAMK protein kinase 0.0078 0.0124 0.0132
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0125 0.0583 0.1944
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0142 0.0745 0.2301
Schistosoma mansoni protein kinase 0.0198 0.1293 0.1699
Brugia malayi Protein kinase domain containing protein 0.0112 0.0457 0.0488
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.01 0.0335 0.0799
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0172 0.1036 0.1247
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.018 0.1117 0.1192
Plasmodium vivax unspecified product 0.0112 0.0448 0.3994
Brugia malayi Protein kinase domain containing protein 0.1011 0.92 0.982
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0125 0.0583 0.0696
Echinococcus multilocularis titin 0.0078 0.0124 0.0137
Toxoplasma gondii AGC kinase 0.0125 0.0583 0.1546
Trichomonas vaginalis CMGC family protein kinase 0.0112 0.0448 0.1538
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0627 0.5465 0.5408
Brugia malayi ephrin receptor 1 precursor 0.0088 0.0214 0.0229
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.0475 0.398 0.4249
Echinococcus granulosus nervana 2 0.0132 0.0649 0.0532
Schistosoma mansoni serine/threonine protein kinase 0.008 0.0144 0.0176
Schistosoma mansoni kinase 0.0088 0.0219 0.0276
Loa Loa (eye worm) CMGC/CDK/CDK8 protein kinase 0.018 0.1113 0.1188
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.0153 0.0852 0.2763
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.018 0.1117 0.1006
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0231 0.1607 0.6003
Loa Loa (eye worm) TK protein kinase 0.0294 0.2223 0.2373
Brugia malayi Immunoglobulin I-set domain containing protein 0.0078 0.0124 0.0132
Brugia malayi Immunoglobulin I-set domain containing protein 0.0294 0.2223 0.2373
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0096 0.0302 0.018
Trichomonas vaginalis AGC family protein kinase 0.0092 0.0255 0.0737
Brugia malayi Protein kinase domain containing protein 0.0219 0.1495 0.1595
Schistosoma mansoni tyrosine kinase 0.0124 0.0565 0.0735
Echinococcus granulosus casein kinase ii subunit alpha 0.0112 0.0448 0.0329
Echinococcus granulosus Protein kinase C brain isozyme 0.0277 0.2056 0.1957
Echinococcus multilocularis dual specificity 0.0153 0.0852 0.1024
Entamoeba histolytica PH domain containing protein kinase, putative 0.0135 0.0676 0.185
Echinococcus granulosus c src tyrosine kinase 0.0152 0.0846 0.0731
Plasmodium falciparum calcium-dependent protein kinase 4 0.0153 0.0848 0.761
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0159 0.0914 0.1098
Brugia malayi SH2 domain containing protein 0.0112 0.0457 0.0488
Schistosoma mansoni serine/threonine kinase 0.018 0.1117 0.1466
Plasmodium falciparum protein kinase, putative 0.0095 0.0288 0.0481
Giardia lamblia Kinase, CMGC MAPK 0.0094 0.0278 0.0034
Trichomonas vaginalis AGC family protein kinase 0.0322 0.2496 1
Schistosoma mansoni protein kinase 0.0112 0.0448 0.058
Echinococcus multilocularis leucine rich repeat serine:threonine protein 0.0102 0.036 0.0425
Trichomonas vaginalis CMGC family protein kinase 0.0153 0.0852 0.3208
Schistosoma mansoni tyrosine kinase 0.0267 0.1962 0.2586
Loa Loa (eye worm) hypothetical protein 0.0297 0.2249 0.2401
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0142 0.0745 0.0894
Entamoeba histolytica protein kinase domain containing protein 0.0142 0.0745 0.2066
Echinococcus granulosus tyrosine protein kinase Src42A 0.0155 0.0871 0.0757
Echinococcus multilocularis CDC7 cell division cycle 7 0.01 0.0341 0.0401
Leishmania major protein kinase, putative 0.0169 0.1005 0.3489
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0097 0.0308 0.0394
Trichomonas vaginalis CMGC family protein kinase 0.0153 0.0852 0.3208
Echinococcus multilocularis cyclin dependent kinase 0.0132 0.0643 0.0769
Echinococcus multilocularis neuroglian 0.0126 0.0589 0.0703
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0125 0.0583 0.1944
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0109 0.0419 0.3696
Loa Loa (eye worm) hypothetical protein 0.0099 0.0328 0.035
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0153 0.0848 0.8079
Schistosoma mansoni growth factor receptor-bound protein 0.0101 0.0346 0.0444
Plasmodium vivax protein kinase Crk2 0.0132 0.0643 0.598
Brugia malayi Protein kinase domain containing protein 0.0083 0.0172 0.0184
Brugia malayi Protein kinase domain containing protein 0.022 0.1501 0.1602
Brugia malayi Protein kinase domain containing protein 0.0112 0.0457 0.0488
Loa Loa (eye worm) TK protein kinase 0.0312 0.2393 0.2555
Trichomonas vaginalis CAMK family protein kinase 0.0293 0.2217 0.885
Loa Loa (eye worm) TK/FER protein kinase 0.0112 0.0457 0.0488
Echinococcus granulosus homeodomain interacting protein kinase 3 0.0221 0.1514 0.1408
Echinococcus multilocularis Glutaredoxin protein 5 0.0132 0.0649 0.0777
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0084 0.0176 0.0187
Entamoeba histolytica protein kinase, putative 0.0153 0.0852 0.2396
Loa Loa (eye worm) TKL/STKR/TYPE2 protein kinase 0.0105 0.0387 0.0413
Trichomonas vaginalis AGC family protein kinase 0.018 0.1117 0.4302
Schistosoma mansoni rap gtpase-activating protein 0.0119 0.0525 0.0682
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0094 0.0278 0.0574
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0293 0.2217 0.2685
Entamoeba histolytica p21-activated kinase 0.0106 0.0395 0.0983
Loa Loa (eye worm) hypothetical protein 0.01 0.0332 0.0354
Giardia lamblia Kinase, CK1 Casein kinase 0.0121 0.0537 0.1365
Brugia malayi SH2 domain containing protein 0.0437 0.3611 0.3854
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0132 0.0643 0.0525
Brugia malayi Egg laying defective protein 4 0.0148 0.0807 0.0861
Trichomonas vaginalis CAMK family protein kinase 0.0153 0.0848 0.319
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.0426 0.3506 0.4253
Brugia malayi Protein kinase domain containing protein 0.0485 0.4085 0.436
Entamoeba histolytica protein kinase, putative 0.008 0.0144 0.0209
Trichomonas vaginalis AGC family protein kinase 0.0322 0.2496 1
Plasmodium vivax glycogen synthase kinase 3, putative 0.0142 0.0745 0.7029
Plasmodium falciparum cGMP-dependent protein kinase 0.0148 0.0807 0.7086
Trichomonas vaginalis CAMK family protein kinase 0.01 0.0337 0.1078
Brugia malayi Protein kinase domain containing protein 0.0381 0.3073 0.328
Echinococcus granulosus NDR protein kinase 0.018 0.1117 0.1006
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.0242 0.1718 0.2077
Schistosoma mansoni serine/threonine kinase 0.0212 0.1428 0.1878
Schistosoma mansoni protein kinase 0.0132 0.0647 0.0843
Echinococcus granulosus serine:threonine protein kinase N2 0.0319 0.2465 0.237
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0159 0.0913 0.0799
Echinococcus multilocularis cyclin dependent kinase 9 0.0096 0.0302 0.0354
Echinococcus granulosus expressed protein 0.0093 0.0272 0.015
Entamoeba histolytica casein kinase, putative 0.0121 0.0537 0.1423
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0397 0.322 0.3906
Echinococcus multilocularis casein kinase I alpha 0.0121 0.0537 0.064
Entamoeba histolytica cell division protein kinase 2, putative 0.014 0.0725 0.2003
Echinococcus multilocularis activin receptor type 0.0487 0.4099 0.4975
Echinococcus multilocularis mitogen activated protein kinase 0.0094 0.0278 0.0325
Brugia malayi Casein kinase II, alpha chain 0.0112 0.0448 0.0479
Echinococcus multilocularis calcium activated potassium channel 0.0116 0.0492 0.0585
Echinococcus multilocularis mitogen activated protein kinase 14 0.031 0.2373 0.2875
Loa Loa (eye worm) hypothetical protein 0.0112 0.0457 0.0488
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0246 0.176 0.2129
Trichomonas vaginalis STE family protein kinase 0.0096 0.0302 0.0932
Brugia malayi Protein kinase domain containing protein 0.0646 0.5645 0.6026
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0397 0.322 0.3135
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0141 0.073 0.2703
Echinococcus granulosus TGF-beta receptor type-1 0.0117 0.0497 0.0377
Echinococcus multilocularis ephrin type A receptor 4 A 0.0124 0.0566 0.0676
Entamoeba histolytica serine/threonine-protein kinase 3, putative 0.0095 0.0288 0.0653
Schistosoma mansoni tyrosine kinase 0.0341 0.2677 0.3534
Schistosoma mansoni tyrosine kinase 0.0246 0.176 0.2319
Schistosoma mansoni tyrosine kinase 0.0437 0.3611 0.4772
Echinococcus granulosus cyclin dependent kinase 0.0132 0.0643 0.0525
Echinococcus multilocularis dual specificity mitogen activated protein 0.0198 0.1293 0.156
Plasmodium falciparum calcium-dependent protein kinase 2 0.0153 0.0848 0.761
Echinococcus multilocularis Immunoglobulin 0.0099 0.0328 0.0386
Trypanosoma cruzi casein kinase II, putative 0.0112 0.0448 0.134
Echinococcus granulosus maternal embryonic leucine zipper kinase 0.0128 0.0604 0.0486
Onchocerca volvulus 0.0297 0.2249 0.2377
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0437 0.3611 0.3531
Plasmodium falciparum casein kinase 2, alpha subunit 0.0112 0.0448 0.2526
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0142 0.0745 0.0973
Loa Loa (eye worm) hypothetical protein 0.0145 0.0771 0.0823
Echinococcus granulosus tyrosine protein kinase ABL1 0.0334 0.2613 0.2521
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.0204 0.1345 0.1436
Trichomonas vaginalis CAMK family protein kinase 0.01 0.0337 0.1078
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.01 0.0335 0.0799
Entamoeba histolytica protein kinase domain containing protein 0.01 0.0335 0.0799
Brugia malayi Tyrosine-protein kinase abl-1 0.0237 0.167 0.1783
Schistosoma mansoni serine/threonine protein kinase 0.0177 0.1086 0.1425
Giardia lamblia Kinase, CMGC GSK 0.0142 0.0745 0.2435
Trichomonas vaginalis AGC family protein kinase 0.015 0.0823 0.3086
Echinococcus granulosus protein tyrosine kinase 0.0842 0.7554 0.7524
Schistosoma mansoni protein kinase 0.0073 0.0076 0.0087
Echinococcus granulosus CDC7 cell division cycle 7 0.01 0.0341 0.022
Onchocerca volvulus 0.0112 0.0457 0.0458
Echinococcus multilocularis expressed conserved protein 0.0148 0.0807 0.0969
Brugia malayi Protein kinase domain containing protein 0.0312 0.2393 0.2555
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0172 0.1036 0.0924
Echinococcus multilocularis epidermal growth factor receptor 0.0659 0.5775 0.7015
Trichomonas vaginalis CMGC family protein kinase 0.0112 0.0448 0.1538
Plasmodium falciparum calcium-dependent protein kinase 1 0.0153 0.0848 0.761
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0231 0.1607 0.655
Schistosoma mansoni atypical protein kinase C 0.0328 0.2556 0.3374
Giardia lamblia Kinase, NEK 0.015 0.0823 0.2834
Loa Loa (eye worm) hypothetical protein 0.0477 0.4002 0.4272
Echinococcus multilocularis N chimaerin 0.011 0.0433 0.0514
Brugia malayi Furin-like cysteine rich region family protein 0.0659 0.5775 0.6164
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.037 0.2962 0.3162
Schistosoma mansoni tyrosine kinase 0.0246 0.176 0.2319
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0246 0.176 0.2129
Echinococcus multilocularis serine:threonine protein kinase 0.0083 0.0172 0.0196
Plasmodium vivax casein kinase 1, putative 0.0121 0.0537 0.4902
Loa Loa (eye worm) TK/FER protein kinase 0.0112 0.0457 0.0488
Giardia lamblia Kinase, CDC7 0.01 0.0341 0.0356
Loa Loa (eye worm) hypothetical protein 0.0119 0.0525 0.0561
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0169 0.1005 0.3843
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0119 0.0525 0.1141
Schistosoma mansoni serine/threonine protein kinase 0.0153 0.0852 0.1115
Brugia malayi serine/threonine kinase 12 0.01 0.0335 0.0358
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.0397 0.322 0.3437

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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