Detailed information for compound 834553

Basic information

Technical information
  • TDR Targets ID: 834553
  • Name: N-butyl-7-chloro-3-(4-ethylphenyl)sulfonyl-N- methyltriazolo[1,5-a]quinazolin-5-amine
  • MW: 457.976 | Formula: C22H24ClN5O2S
  • H donors: 0 H acceptors: 5 LogP: 5.38 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCCN(c1nc2n(c3c1cc(Cl)cc3)nnc2S(=O)(=O)c1ccc(cc1)CC)C
  • InChi: 1S/C22H24ClN5O2S/c1-4-6-13-27(3)20-18-14-16(23)9-12-19(18)28-21(24-20)22(25-26-28)31(29,30)17-10-7-15(5-2)8-11-17/h7-12,14H,4-6,13H2,1-3H3
  • InChiKey: CSDTUWDLSFSHRO-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N-butyl-7-chloro-3-(4-ethylphenyl)sulfonyl-N-methyl-triazolo[1,5-a]quinazolin-5-amine
  • N-butyl-7-chloro-3-(4-ethylphenyl)sulfonyl-N-methyl-5-triazolo[1,5-a]quinazolinamine
  • butyl-[7-chloro-3-(4-ethylphenyl)sulfonyl-triazolo[1,5-a]quinazolin-5-yl]-methyl-amine
  • N-butyl-7-chloro-3-(4-ethylphenyl)sulfonyl-N-methyl-[1,2,3]triazolo[1,5-a]quinazolin-5-amine
  • C718-1387
  • NCGC00112280-01

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Equus caballus Ferritin light chain Starlite/ChEMBL No references
Homo sapiens tumor protein p53 Starlite/ChEMBL No references
Homo sapiens chromobox homolog 1 Starlite/ChEMBL No references
Escherichia coli penicillin-binding protein Starlite/ChEMBL No references
Homo sapiens lysine (K)-specific demethylase 4A Starlite/ChEMBL No references
Homo sapiens survival of motor neuron 2, centromeric Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Echinococcus multilocularis tumor protein p63 Get druggable targets OG5_140038 All targets in OG5_140038
Brugia malayi hypothetical protein Get druggable targets OG5_132873 All targets in OG5_132873
Schistosoma mansoni chromobox protein Get druggable targets OG5_129545 All targets in OG5_129545
Candida albicans one of two closely related potential jumonji-like transcription factor genes similar to S. cerevisiae RPH1 (YER169W) damage-resp Get druggable targets OG5_127917 All targets in OG5_127917
Trichomonas vaginalis chromobox protein, putative Get druggable targets OG5_129545 All targets in OG5_129545
Schistosoma japonicum JmjC domain-containing histone demethylation protein 3C, putative Get druggable targets OG5_127917 All targets in OG5_127917
Trichomonas vaginalis chromobox protein, putative Get druggable targets OG5_129545 All targets in OG5_129545
Schistosoma japonicum Probable JmjC domain-containing histone demethylation protein 3B, putative Get druggable targets OG5_127917 All targets in OG5_127917
Echinococcus multilocularis Transcription factor, JmjC domain containing protein Get druggable targets OG5_127917 All targets in OG5_127917
Schistosoma japonicum expressed protein Get druggable targets OG5_127917 All targets in OG5_127917
Echinococcus multilocularis chromobox protein 1 Get druggable targets OG5_129545 All targets in OG5_129545
Echinococcus multilocularis jumonji domain containing protein Get druggable targets OG5_127917 All targets in OG5_127917
Loa Loa (eye worm) heterochromatin protein 1 Get druggable targets OG5_129545 All targets in OG5_129545
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_127917 All targets in OG5_127917
Mycobacterium tuberculosis Possible penicillin-binding protein Get druggable targets OG5_149948 All targets in OG5_149948
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_129545 All targets in OG5_129545
Candida albicans one of two closely related potential jumonji-like transcription factor genes similar to S. cerevisiae RPH1 (YER169W) damage-resp Get druggable targets OG5_127917 All targets in OG5_127917
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_132873 All targets in OG5_132873
Echinococcus multilocularis chromobox protein 1 Get druggable targets OG5_129545 All targets in OG5_129545
Echinococcus granulosus Transcription factor JmjC domain containing protein Get druggable targets OG5_127917 All targets in OG5_127917
Trichomonas vaginalis chromobox protein, putative Get druggable targets OG5_129545 All targets in OG5_129545
Brugia malayi Heterochromatin protein 1 Get druggable targets OG5_129545 All targets in OG5_129545
Schistosoma japonicum expressed protein Get druggable targets OG5_127917 All targets in OG5_127917
Echinococcus granulosus chromobox protein 1 Get druggable targets OG5_129545 All targets in OG5_129545
Schistosoma mansoni chromobox protein Get druggable targets OG5_129545 All targets in OG5_129545
Onchocerca volvulus Get druggable targets OG5_129545 All targets in OG5_129545
Plasmodium yoelii hypothetical protein Get druggable targets OG5_127917 All targets in OG5_127917
Theileria parva hypothetical protein Get druggable targets OG5_129545 All targets in OG5_129545
Loa Loa (eye worm) jmjC domain-containing protein Get druggable targets OG5_127917 All targets in OG5_127917
Echinococcus granulosus tumor protein p63 Get druggable targets OG5_140038 All targets in OG5_140038
Trichomonas vaginalis chromobox protein, putative Get druggable targets OG5_129545 All targets in OG5_129545
Echinococcus granulosus survival motor neuron protein 1 Get druggable targets OG5_132873 All targets in OG5_132873
Echinococcus multilocularis survival motor neuron protein 1 Get druggable targets OG5_132873 All targets in OG5_132873
Schistosoma japonicum Chromobox protein homolog 5, putative Get druggable targets OG5_129545 All targets in OG5_129545
Candida albicans one of two closely related potential jumonji-like transcription factor genes similar to S. cerevisiae RPH1 (YER169W) damage-resp Get druggable targets OG5_127917 All targets in OG5_127917
Candida albicans one of two closely related potential jumonji-like transcription factor genes similar to S. cerevisiae RPH1 (YER169W) damage-resp Get druggable targets OG5_127917 All targets in OG5_127917
Onchocerca volvulus Heterochromatin protein 1 homolog Get druggable targets OG5_129545 All targets in OG5_129545
Echinococcus granulosus jumonji domain containing protein Get druggable targets OG5_127917 All targets in OG5_127917
Schistosoma mansoni jumonji domain containing protein Get druggable targets OG5_127917 All targets in OG5_127917
Brugia malayi jmjC domain containing protein Get druggable targets OG5_127917 All targets in OG5_127917
Echinococcus granulosus chromobox protein 1 Get druggable targets OG5_129545 All targets in OG5_129545
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Schistosoma mansoni ferritin Ferritin light chain   175 aa 171 aa 43.9 %
Schistosoma mansoni apoferritin-2 Ferritin light chain   175 aa 146 aa 28.8 %
Schistosoma mansoni apoferritin-2 Ferritin light chain   175 aa 142 aa 29.6 %
Echinococcus multilocularis expressed protein Ferritin light chain   175 aa 146 aa 30.1 %
Schistosoma japonicum Ferritin, putative Ferritin light chain   175 aa 144 aa 24.3 %
Echinococcus granulosus expressed protein Ferritin light chain   175 aa 146 aa 28.8 %
Schistosoma mansoni ferritin Ferritin light chain   175 aa 171 aa 44.4 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0054 0.0105 0.0301
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.03 0.1014 0.3839
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0079 0.0198
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0107 0.03 0.0336
Schistosoma mansoni cathepsin D (A01 family) 0.014 0.0422 0.0423
Schistosoma mansoni biogenic amine receptor 0.0308 0.1043 0.105
Brugia malayi hypothetical protein 0.0308 0.1043 0.2378
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0148 0.0452 0.1019
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0148 0.0452 0.0508
Brugia malayi jmjC domain containing protein 0.0043 0.0062 0.0122
Loa Loa (eye worm) hypothetical protein 0.0308 0.1043 0.2378
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.0068 0.0157 0.0174
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0148 0.0452 0.1019
Toxoplasma gondii beta-1 tubulin, putative 0.043 0.1497 0.1497
Loa Loa (eye worm) SWIB/MDM2 domain-containing protein 0.0129 0.0381 0.0856
Echinococcus multilocularis integrin alpha ps 0.0137 0.0412 0.0463
Leishmania major hypothetical protein, conserved 0.0046 0.0074 0.0061
Plasmodium falciparum SWIB/MDM2 domain-containing protein 0.0129 0.0381 0.237
Toxoplasma gondii subtilisin SUB11 0.0054 0.0105 0.0105
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0308 0.1043 0.105
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0119 0.0343 0.1942
Schistosoma mansoni neurotransmitter gated ion channel 0.0068 0.0157 0.0155
Brugia malayi neuropeptide F receptor 0.0308 0.1043 0.2378
Loa Loa (eye worm) hypothetical protein 0.006 0.0125 0.0267
Trichomonas vaginalis conserved hypothetical protein 0.0246 0.0814 0.3057
Loa Loa (eye worm) hypothetical protein 0.0047 0.0079 0.016
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0135 0.0403 0.0906
Onchocerca volvulus 0.0135 0.0403 0.1697
Schistosoma mansoni matrix metallopeptidase-7 (M10 family) 0.0028 0.0009 0.0006
Trypanosoma cruzi ribonucleoside-diphosphate reductase large chain, putative 0.0083 0.021 0.1012
Schistosoma mansoni subfamily S8B unassigned peptidase (S08 family) 0.0054 0.0105 0.0103
Loa Loa (eye worm) hypothetical protein 0.0308 0.1043 0.2378
Brugia malayi serine/threonine protein kinase 6 0.0059 0.0123 0.0263
Schistosoma mansoni nuclear receptor nhr-48 0.005 0.0091 0.0089
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0308 0.1043 0.1177
Echinococcus granulosus glycine receptor subunit beta 0.0148 0.0452 0.0508
Brugia malayi hypothetical protein 0.0308 0.1043 0.2378
Schistosoma mansoni glutamate receptor AMPA 0.0032 0.0022 0.0019
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0107 0.03 0.0336
Brugia malayi ribonucleoside-diphosphate reductase large chain, putative 0.0083 0.021 0.0462
Trichomonas vaginalis conserved hypothetical protein 0.0246 0.0814 0.3057
Brugia malayi Steroid receptor seven-up type 2 0.0107 0.03 0.067
Trichomonas vaginalis chromobox protein, putative 0.0084 0.0216 0.0731
Brugia malayi hypothetical protein 0.0068 0.0157 0.034
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0148 0.0452 0.0453
Echinococcus multilocularis tyrosine protein kinase Fyn 0.004 0.0053 0.0057
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0308 0.1043 0.1177
Giardia lamblia Furin precursor putative serine protease 0.0246 0.0814 0.5327
Echinococcus multilocularis fmrfamide receptor 0.0308 0.1043 0.1177
Schistosoma mansoni opsin-like receptor 0.0308 0.1043 0.105
Loa Loa (eye worm) hypothetical protein 0.0032 0.0024 0.0033
Schistosoma mansoni histamine h1 receptor 0.0308 0.1043 0.105
Plasmodium falciparum subtilisin-like protease 1 0.0054 0.0105 0.0483
Loa Loa (eye worm) TK/ALK protein kinase 0.003 0.0016 0.0017
Loa Loa (eye worm) hypothetical protein 0.0308 0.1043 0.2378
Schistosoma mansoni hypothetical protein 0.0072 0.017 0.0168
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0054 0.0105 0.0301
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0308 0.1043 0.105
Loa Loa (eye worm) hypothetical protein 0.006 0.0128 0.0273
Onchocerca volvulus 0.0308 0.1043 0.4454
Brugia malayi PAN domain containing protein 0.0201 0.065 0.1474
Toxoplasma gondii PAN domain-containing protein 0.2727 1 1
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0107 0.03 0.067
Echinococcus granulosus furin 0.1179 0.4269 0.483
Schistosoma mansoni fusion 0.0046 0.0074 0.0071
Schistosoma mansoni hypothetical protein 0.0198 0.0637 0.064
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0148 0.0452 0.0508
Echinococcus granulosus neuropeptides capa receptor 0.0308 0.1043 0.1177
Trypanosoma cruzi subtilisin peptidase 0.0054 0.0105 0.0279
Brugia malayi Trypsin family protein 0.0135 0.0403 0.0906
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0119 0.0343 0.1942
Schistosoma mansoni cellular tumor antigen P53 0.006 0.0125 0.0123
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.008 0.02 0.0198
Trichomonas vaginalis conserved hypothetical protein 0.0246 0.0814 0.3057
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0135 0.0403 0.0404
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0107 0.03 0.0336
Mycobacterium leprae Probable lipase LipE 0.0043 0.0065 0.0108
Schistosoma mansoni neurotransmitter gated ion channel 0.0068 0.0157 0.0155
Trichomonas vaginalis replication factor A 1, rfa1, putative 0.0103 0.0285 0.1002
Schistosoma mansoni zinc finger protein 0.0046 0.0074 0.0071
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.01 0.0274 0.0307
Echinococcus multilocularis somatostatin receptor 0.0308 0.1043 0.1177
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0278 0.0933 0.2977
Schistosoma mansoni cercarial elastase (S01 family) 0.0135 0.0403 0.0404
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0148 0.0452 0.0508
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0148 0.0452 0.0508
Schistosoma mansoni RNA binding protein 0.0046 0.0074 0.0071
Schistosoma mansoni hypothetical protein 0.0308 0.1043 0.105
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0148 0.0452 0.0508
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0308 0.1043 0.1177
Loa Loa (eye worm) PAN domain-containing protein 0.0201 0.065 0.1474
Brugia malayi hypothetical protein 0.0308 0.1043 0.2378
Trichomonas vaginalis glucosylceramidase, putative 0.0167 0.0523 0.1928
Echinococcus granulosus rhodopsin orphan GPCR 0.0308 0.1043 0.1177
Entamoeba histolytica replication factor A protein 1, putative 0.0044 0.0068 0.0096
Schistosoma mansoni tyrosine kinase 0.0735 0.2625 0.2647
Echinococcus granulosus tyrosine protein kinase Fyn 0.0044 0.0067 0.0072
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0308 0.1043 0.1177
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0308 0.1043 0.2378
Brugia malayi hypothetical protein 0.0032 0.0024 0.0033
Loa Loa (eye worm) integrin beta-2 0.0313 0.1062 0.242
Trichomonas vaginalis replication factor A 1, rfa1, putative 0.0049 0.0087 0.023
Echinococcus granulosus glycoprotein Antigen 5 0.0135 0.0403 0.0453
Brugia malayi Hypothetical subtilase-type proteinase F21H12.6 in chromosome II 0.0054 0.0105 0.0221
Trypanosoma brucei serine peptidase, clan SB, family S8-like protein 0.0065 0.0146 0.0241
Schistosoma mansoni nAChR subunit 0.0068 0.0157 0.0155
Brugia malayi hypothetical protein 0.0032 0.0024 0.0033
Brugia malayi Protein kinase domain containing protein 0.003 0.0016 0.0017
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0148 0.0452 0.1019
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.03 0.1014 0.3839
Trichomonas vaginalis AGC family protein kinase 0.0059 0.0123 0.0372
Loa Loa (eye worm) tubulin beta chain 0.043 0.1497 0.3422
Loa Loa (eye worm) hypothetical protein 0.0043 0.0065 0.0129
Echinococcus multilocularis Zinc finger, RanBP2 type 0.0046 0.0074 0.008
Brugia malayi G-protein coupled receptor 0.0308 0.1043 0.2378
Echinococcus multilocularis tyrosine protein kinase Blk 0.004 0.0053 0.0057
Echinococcus multilocularis SWI:SNF matrix associated 0.0129 0.0381 0.0428
Echinococcus granulosus tgf beta family 0.0032 0.0024 0.0023
Brugia malayi endoprotease bli-4 precursor 0.1179 0.4269 0.9798
Loa Loa (eye worm) hypothetical protein 0.0308 0.1043 0.2378
Brugia malayi Dopamine receptor 0.0308 0.1043 0.2378
Onchocerca volvulus 0.0201 0.065 0.276
Echinococcus multilocularis g protein coupled receptor 0.0308 0.1043 0.1177
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0148 0.0452 0.1019
Loa Loa (eye worm) hypothetical protein 0.0308 0.1043 0.2378
Plasmodium falciparum subtilisin-like protease 2 0.0054 0.0105 0.0483
Echinococcus multilocularis Tubulin beta 2C chain 0.043 0.1497 0.1691
Echinococcus granulosus tyrosine protein kinase Src42A 0.0044 0.0067 0.0072
Loa Loa (eye worm) hypothetical protein 0.0057 0.0113 0.024
Echinococcus multilocularis sex peptide receptor 0.0308 0.1043 0.1177
Schistosoma mansoni coup transcription factor 0.0107 0.03 0.03
Loa Loa (eye worm) G-protein coupled receptor 0.0308 0.1043 0.2378
Schistosoma mansoni thyroid hormone receptor 0.0107 0.03 0.03
Trichomonas vaginalis conserved hypothetical protein 0.0246 0.0814 0.3057
Echinococcus granulosus enteropeptidase 0.0135 0.0403 0.0453
Brugia malayi Cation transporter family protein 0.0148 0.0452 0.1019
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0057 0.0113 0.0125
Schistosoma mansoni ephrin receptor 0.0198 0.0636 0.0639
Brugia malayi Glutamate receptor 1 precursor 0.0032 0.0022 0.0029
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0308 0.1043 0.2378
Loa Loa (eye worm) trypsin family protein 0.0135 0.0403 0.0906
Leishmania major beta tubulin 0.043 0.1497 1
Brugia malayi photoreceptor-specific nuclear receptor 0.0107 0.03 0.067
Trichomonas vaginalis AGC family protein kinase 0.0059 0.0123 0.0372
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0054 0.0105 0.0301
Echinococcus multilocularis tgf beta family 0.0032 0.0024 0.0023
Brugia malayi Nuclear hormone receptor-like 1 0.0057 0.0113 0.024
Schistosoma mansoni cercarial elastase (S01 family) 0.0135 0.0403 0.0404
Loa Loa (eye worm) hypothetical protein 0.0037 0.0041 0.0073
Loa Loa (eye worm) latrophilin receptor protein 2 0.0078 0.0194 0.0426
Brugia malayi PAN domain containing protein 0.0201 0.065 0.1474
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0078 0.0194 0.0216
Loa Loa (eye worm) deoxyribonuclease II family protein 0.008 0.0199 0.0436
Schistosoma mansoni hypothetical protein 0.0078 0.0194 0.0193
Loa Loa (eye worm) hypothetical protein 0.0294 0.0994 0.2264
Loa Loa (eye worm) hypothetical protein 0.0308 0.1043 0.2378
Trichomonas vaginalis glucosylceramidase, putative 0.0167 0.0523 0.1928
Echinococcus granulosus sodium channel protein 0.0086 0.0224 0.0249
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0048 0.0082 0.0089
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0294 0.0994 0.2264
Echinococcus multilocularis tubulin beta 1 chain 0.043 0.1497 0.1691
Echinococcus granulosus tubulin beta 1 chain 0.043 0.1497 0.1691
Loa Loa (eye worm) hypothetical protein 0.0068 0.0157 0.0339
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0047 0.0079 0.03
Loa Loa (eye worm) hypothetical protein 0.0201 0.065 0.1474
Echinococcus granulosus Nuclear hormone receptor HR96 0.005 0.0091 0.01
Onchocerca volvulus 0.0135 0.0403 0.1697
Trichomonas vaginalis replication factor A 1, rfa1, putative 0.0098 0.0267 0.0929
Schistosoma mansoni tubulin subunit beta 0.043 0.1497 0.1508
Loa Loa (eye worm) deoxyribonuclease II family protein 0.008 0.0199 0.0436
Trichomonas vaginalis deoxyribonuclease II precursor, putative 0.008 0.0199 0.0665
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0308 0.1043 0.1177
Trichomonas vaginalis ribonucleoside-diphosphate reductase alpha chain, putative 0.0083 0.021 0.0709
Loa Loa (eye worm) heterochromatin protein 1 0.0084 0.0216 0.0475
Brugia malayi GnHR receptor homolog 0.0308 0.1043 0.2378
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0255 0.0848 0.1929
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.03 0.1014 0.3839
Mycobacterium leprae RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE (ALPHA CHAIN) NRDE (RIBONUCLEOTIDE REDUCTASE SMALL SUBUNIT) (R1F PROTEIN) 0.0343 0.1175 0.3725
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0308 0.1043 0.105
Loa Loa (eye worm) hypothetical protein 0.0363 0.125 0.2853
Schistosoma mansoni neuropeptide receptor 0.0308 0.1043 0.105
Echinococcus granulosus tyrosine protein kinase Fyn 0.0044 0.0067 0.0072
Loa Loa (eye worm) TK/INSR protein kinase 0.0192 0.0616 0.1396
Toxoplasma gondii subtilisin SUB8 0.0054 0.0105 0.0105
Loa Loa (eye worm) bone morphogenic protein 6 0.0126 0.0371 0.0832
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0043 0.0065 0.0108
Toxoplasma gondii ribonucleoside-diphosphate reductase large chain 0.0083 0.021 0.021
Loa Loa (eye worm) hypothetical protein 0.0043 0.0065 0.0129
Loa Loa (eye worm) PAN domain-containing protein 0.0201 0.065 0.1474
Schistosoma mansoni nAChR subunit 0.0148 0.0452 0.0453
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0054 0.0105 0.0301
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.03 0.1014 0.3839
Toxoplasma gondii microneme protein MIC17C 0.0201 0.065 0.065
Loa Loa (eye worm) hypothetical protein 0.0135 0.0403 0.0906
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.0198 0.0637 0.1444
Schistosoma mansoni site-1 peptidase (S08 family) 0.0054 0.0105 0.0103
Schistosoma mansoni glutamate receptor kainate 0.0032 0.0022 0.0019
Echinococcus granulosus peptide allatostatin:somatostatin 0.0308 0.1043 0.1177
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0308 0.1043 0.2378
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0054 0.0105 0.0301
Loa Loa (eye worm) hypothetical protein 0.0148 0.0452 0.1019
Onchocerca volvulus 0.0032 0.0024 0.0062
Trichomonas vaginalis glucosylceramidase, putative 0.0167 0.0523 0.1928
Echinococcus multilocularis aurora kinase A 0.0059 0.0123 0.0136
Echinococcus multilocularis glutamate receptor 2 0.0048 0.0082 0.0089
Schistosoma mansoni opsin-like receptor 0.0308 0.1043 0.105
Echinococcus granulosus somatostatin receptor 0.0308 0.1043 0.1177
Echinococcus granulosus glutamate NMDA receptor subunit 0.0267 0.0894 0.1008
Schistosoma mansoni zinc finger protein 0.005 0.0091 0.0089
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.011 0.0312 0.0697
Loa Loa (eye worm) integrin alpha pat-2 0.0472 0.1651 0.3776
Mycobacterium tuberculosis Probable esterase LipL 0.0043 0.0065 0.0165
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0308 0.1043 0.105
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.005 0.0091 0.0089
Trichomonas vaginalis conserved hypothetical protein 0.0246 0.0814 0.3057
Schistosoma mansoni hypothetical protein 0.0066 0.0148 0.0146
Mycobacterium ulcerans ribonucleotide-diphosphate reductase subunit alpha 0.0343 0.1175 0.3725
Entamoeba histolytica protein kinase, putative 0.0059 0.0123 0.0276
Loa Loa (eye worm) hypothetical protein 0.005 0.0091 0.0188
Brugia malayi hypothetical protein 0.0308 0.1043 0.2378
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0476 0.1665 0.1678
Loa Loa (eye worm) hypothetical protein 0.0308 0.1043 0.2378
Trichomonas vaginalis tubulin alpha chain, putative 0.043 0.1497 0.5716
Echinococcus granulosus glycine receptor subunit alpha 1 0.0148 0.0452 0.0508
Onchocerca volvulus 0.0201 0.065 0.276
Brugia malayi jmjC domain containing protein 0.0115 0.0331 0.0741
Onchocerca volvulus Neuropeptide F receptor homolog 0.0308 0.1043 0.4454
Trichomonas vaginalis conserved hypothetical protein 0.0246 0.0814 0.3057
Echinococcus granulosus neuropeptide Y receptor 0.0308 0.1043 0.1177
Loa Loa (eye worm) melatonin receptor type 1A 0.0308 0.1043 0.2378
Schistosoma mansoni amine GPCR 0.0308 0.1043 0.105
Toxoplasma gondii subtilisin SUB2 0.0054 0.0105 0.0105
Onchocerca volvulus 0.006 0.0125 0.05
Loa Loa (eye worm) AUR protein kinase 0.0059 0.0123 0.0263
Trichomonas vaginalis penicillin-binding protein, putative 0.0043 0.0065 0.0145
Echinococcus granulosus sex peptide receptor 0.0308 0.1043 0.1177
Brugia malayi PAN domain containing protein 0.0201 0.065 0.1474
Loa Loa (eye worm) growth/differentiation factor 10 0.0032 0.0024 0.0033
Loa Loa (eye worm) SRC-1 0.0044 0.0067 0.0133
Echinococcus granulosus membrane bound transcription factor site 1 0.0054 0.0105 0.0115
Echinococcus granulosus g protein coupled receptor 0.0308 0.1043 0.1177
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0059 0.0123 0.0136
Trichomonas vaginalis conserved hypothetical protein 0.0054 0.0105 0.0301
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.01 0.0274 0.061
Echinococcus granulosus Tubulin beta 2C chain 0.043 0.1497 0.1691
Trypanosoma brucei ribonucleoside-diphosphate reductase large chain 0.0083 0.021 0.0433
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.01 0.0274 0.0307
Loa Loa (eye worm) matrixin family protein 0.0063 0.0137 0.0294
Schistosoma mansoni glutamate receptor AMPA 0.0032 0.0022 0.0019
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0054 0.0105 0.0301
Trypanosoma cruzi hypothetical protein, conserved 0.0046 0.0074 0.0061
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0135 0.0403 0.0404
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.008 0.02 0.0438
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.005 0.0091 0.0089
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.0068 0.0157 0.034
Entamoeba histolytica tubulin family protein 0.043 0.1497 0.4763
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0179 0.0568 0.1286
Trichomonas vaginalis conserved hypothetical protein 0.0129 0.0381 0.1375
Loa Loa (eye worm) BEN-1 protein 0.043 0.1497 0.3422
Loa Loa (eye worm) hypothetical protein 0.0308 0.1043 0.2378
Loa Loa (eye worm) PHD-finger family protein 0.0035 0.0035 0.0058
Loa Loa (eye worm) hypothetical protein 0.0148 0.0452 0.1019
Mycobacterium tuberculosis Probable membrane-anchored mycosin MycP3 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-3) 0.0054 0.0105 0.0295
Echinococcus multilocularis rhodopsin orphan GPCR 0.0308 0.1043 0.1177
Brugia malayi nuclear hormone receptor 0.0107 0.03 0.067
Loa Loa (eye worm) hypothetical protein 0.008 0.02 0.0438
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0054 0.0105 0.0301
Schistosoma mansoni neuropeptide f receptor 76f 0.0308 0.1043 0.105
Loa Loa (eye worm) hypothetical protein 0.0098 0.0269 0.0597
Brugia malayi PAN domain containing protein 0.0201 0.065 0.1474
Echinococcus multilocularis sodium channel protein 0.0086 0.0224 0.0249
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0308 0.1043 0.1177
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0044 0.0067 0.0072
Schistosoma mansoni integrin alpha 0.0306 0.1037 0.1044
Toxoplasma gondii beta-tubulin, putative 0.043 0.1497 0.1497
Echinococcus granulosus membrane associated guanylate kinase ww and pdz 0.005 0.0091 0.0099
Echinococcus granulosus Tubulin beta 2C chain 0.043 0.1497 0.1691
Schistosoma mansoni integrin alpha-ps 0.0137 0.0412 0.0413
Loa Loa (eye worm) nuclear receptor nhr-7B 0.005 0.0091 0.0188
Leishmania major beta tubulin 0.043 0.1497 1
Echinococcus granulosus tubulin subunit beta 0.043 0.1497 0.1691
Echinococcus granulosus insulin growth factor 1 receptor beta 0.02 0.0643 0.0724
Loa Loa (eye worm) hypothetical protein 0.0107 0.03 0.067
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0044 0.0067 0.0072
Onchocerca volvulus Bile acid receptor homolog 0.0107 0.03 0.1254
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0308 0.1043 0.2378
Echinococcus granulosus beta LACTamase domain containing family member 0.0043 0.0065 0.007
Loa Loa (eye worm) hypothetical protein 0.0308 0.1043 0.2378
Trypanosoma brucei beta tubulin 0.043 0.1497 0.4283
Mycobacterium leprae conserved hypothetical protein 0.0043 0.0065 0.0108
Loa Loa (eye worm) hypothetical protein 0.0308 0.1043 0.2378
Schistosoma mansoni growth hormone secretagogue receptor 0.0308 0.1043 0.105
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0107 0.03 0.03
Toxoplasma gondii aurora kinase 0.0059 0.0123 0.0123
Trichomonas vaginalis conserved hypothetical protein 0.0246 0.0814 0.3057
Echinococcus multilocularis segment polarity protein dishevelled 0.0098 0.0269 0.0301
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0294 0.0994 0.1121
Onchocerca volvulus 0.0308 0.1043 0.4454
Loa Loa (eye worm) hypothetical protein 0.008 0.02 0.0438
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0119 0.0343 0.1942
Mycobacterium leprae PROBABLE PROLINE RICH MEMBRANE-ANCHORED MYCOSIN MYCP5 (SERINE PROTEASE) (SUBTILISIN-LIKE PROTEASE) (SUBTILASE-LIKE) (MYCOSIN-5) 0.0054 0.0105 0.0238
Schistosoma mansoni nuclear hormone receptor 0.005 0.0091 0.0089
Toxoplasma gondii PAN domain-containing protein 0.0201 0.065 0.065
Brugia malayi neuropeptide F receptor 0.0308 0.1043 0.2378
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0148 0.0452 0.0508
Echinococcus granulosus tachykinin peptides receptor 99D 0.0308 0.1043 0.1177
Trichomonas vaginalis penicillin-binding protein, putative 0.0043 0.0065 0.0145
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0308 0.1043 0.1177
Trichomonas vaginalis neuroendocrine convertase 2 precursor, putative 0.0246 0.0814 0.3057
Trichomonas vaginalis glucosylceramidase, putative 0.0167 0.0523 0.1928
Echinococcus granulosus rhodopsin orphan GPCR 0.0308 0.1043 0.1177
Echinococcus multilocularis enteropeptidase 0.0135 0.0403 0.0453
Schistosoma mansoni hypothetical protein 0.0946 0.3408 0.3437
Echinococcus multilocularis tumor protein p63 0.0408 0.1415 0.1599
Brugia malayi hypothetical protein 0.0047 0.008 0.0163
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.005 0.0091 0.01
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0057 0.0113 0.024
Echinococcus multilocularis replication protein A 70 kDa DNA binding 0.0103 0.0285 0.032
Echinococcus multilocularis chromobox protein 1 0.0084 0.0216 0.0241
Schistosoma mansoni hypothetical protein 0.0198 0.0637 0.064
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0059 0.0123 0.0276
Schistosoma mansoni integrin alpha-ps 0.0071 0.0169 0.0167
Echinococcus granulosus tyrosine kinase 0.004 0.0053 0.0057
Echinococcus granulosus beta tubulin 0.043 0.1497 0.1691
Loa Loa (eye worm) hypothetical protein 0.008 0.02 0.0438
Echinococcus granulosus 7tm_1 domain containing protein 0.0308 0.1043 0.1177
Loa Loa (eye worm) hypothetical protein 0.1179 0.4269 0.9798
Loa Loa (eye worm) hypothetical protein 0.0135 0.0403 0.0906
Onchocerca volvulus 0.0046 0.0074 0.0279
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0135 0.0403 0.0453
Echinococcus granulosus G protein coupled receptor 139 0.0308 0.1043 0.1177
Onchocerca volvulus 0.0308 0.1043 0.4454
Schistosoma mansoni tyrosine kinase 0.0321 0.1093 0.1101
Schistosoma mansoni amine GPCR 0.0308 0.1043 0.105
Loa Loa (eye worm) hypothetical protein 0.0068 0.0157 0.0339
Trypanosoma brucei hypothetical protein 0.0119 0.0343 0.0832
Echinococcus multilocularis nAChR subunit 0.008 0.02 0.0222
Loa Loa (eye worm) hypothetical protein 0.0107 0.03 0.067
Echinococcus granulosus hypothetical protein 0.0308 0.1043 0.1177
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0148 0.0452 0.1019
Plasmodium vivax tubulin beta chain, putative 0.043 0.1497 1
Brugia malayi hypothetical protein 0.0308 0.1043 0.2378
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0119 0.0343 0.1942
Leishmania major beta tubulin 0.043 0.1497 1
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0148 0.0452 0.1019
Trypanosoma brucei mitochondrial RNA binding complex 1 subunit 0.0046 0.0074 0.0026
Onchocerca volvulus 0.0308 0.1043 0.4454
Trypanosoma cruzi serine peptidase, clan SB, family S8-like protein 0.0054 0.0105 0.0279
Giardia lamblia Beta tubulin 0.043 0.1497 1
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0054 0.0105 0.0301
Schistosoma mansoni nAChR subunit 0.0148 0.0452 0.0453
Brugia malayi serine/threonine-protein kinase 6 0.0059 0.0123 0.0263
Giardia lamblia Aurora kinase 0.0059 0.0123 0.0607
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0068 0.0157 0.0174
Brugia malayi Trypsin family protein 0.0135 0.0403 0.0906
Brugia malayi Protein kinase domain containing protein 0.0192 0.0616 0.1397
Echinococcus multilocularis matrix metallopeptidase 7 (M10 family) 0.0063 0.0137 0.0152
Onchocerca volvulus Putative nachr subunit 0.0294 0.0994 0.4241
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0119 0.0343 0.0832
Echinococcus granulosus integrin alpha ps 0.0066 0.0148 0.0164
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0057 0.0113 0.0125
Giardia lamblia Beta tubulin 0.043 0.1497 1
Toxoplasma gondii beta tubulin 0.043 0.1497 0.1497
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0043 0.0065 0.0165
Echinococcus multilocularis neuropeptide receptor 0.0308 0.1043 0.1177
Onchocerca volvulus Ubiquitin thioesterase ZRANB1 homolog 0.0046 0.0074 0.0279
Trichomonas vaginalis D-aminoacylase, putative 0.0043 0.0065 0.0145
Loa Loa (eye worm) hypothetical protein 0.0308 0.1043 0.2378
Onchocerca volvulus 0.008 0.02 0.082
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0308 0.1043 0.1177
Echinococcus multilocularis rhodopsin orphan GPCR 0.0308 0.1043 0.1177
Brugia malayi Trypsin family protein 0.0135 0.0403 0.0906
Brugia malayi Serotonin receptor 0.0308 0.1043 0.2378
Trichomonas vaginalis tubulin gamma chain, putative 0.043 0.1497 0.5716
Plasmodium vivax subtilisin-like protease 2, putative 0.0054 0.0105 0.0483
Echinococcus granulosus Upstream activation factor subunit UAF30 0.0129 0.0381 0.0428
Schistosoma mansoni cathepsin D (A01 family) 0.014 0.0422 0.0423
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0107 0.03 0.067
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0107 0.03 0.03
Onchocerca volvulus 0.0521 0.1832 0.7851
Mycobacterium leprae PROBABLE MEMBRANE-ANCHORED MYCOSIN MYCP3 (SERINE PROTEASE) (SUBTILISIN-LIKE PROTEASE) (SUBTILASE-LIKE) (MYCOSIN-3) 0.0054 0.0105 0.0238
Brugia malayi serine/threonine kinase 12 0.0059 0.0123 0.0263
Loa Loa (eye worm) hypothetical protein 0.0107 0.03 0.067
Plasmodium vivax subtilisin-like serine protease, putative 0.0054 0.0105 0.0483
Brugia malayi excitatory GABA receptor EXP-1A 0.0148 0.0452 0.1019
Loa Loa (eye worm) hypothetical protein 0.0035 0.0032 0.0053
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0054 0.0105 0.0301
Toxoplasma gondii ran binding protein 0.0046 0.0074 0.0074
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0308 0.1043 0.1177
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0308 0.1043 0.105
Plasmodium vivax hypothetical protein, conserved 0.0129 0.0381 0.237
Echinococcus granulosus membrane associated guanylate kinase ww and pdz 0.007 0.0162 0.018
Mycobacterium ulcerans hypothetical protein 0.0135 0.0403 0.1209
Leishmania major hypothetical protein, conserved 0.0046 0.0074 0.0061
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0044 0.0067 0.0072
Loa Loa (eye worm) hypothetical protein 0.0476 0.1665 0.381
Schistosoma mansoni nAChR subunit 0.0068 0.0157 0.0155
Plasmodium falciparum ribonucleoside-diphosphate reductase large subunit, putative 0.0083 0.021 0.12
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.008 0.02 0.0438
Brugia malayi hypothetical protein 0.0068 0.0157 0.034
Echinococcus granulosus integrin beta 2 0.0232 0.0762 0.0859
Schistosoma mansoni biogenic amine receptor 0.0308 0.1043 0.105
Schistosoma mansoni adenoreceptor 0.0308 0.1043 0.105
Schistosoma mansoni hypothetical protein 0.0135 0.0403 0.0404
Loa Loa (eye worm) aspartic protease BmAsp-2 0.0047 0.008 0.0162
Trichomonas vaginalis chromobox protein, putative 0.0084 0.0216 0.0731
Leishmania major replication factor A, 51kDa subunit, putative 0.0049 0.0087 0.0152
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0043 0.0065 0.0165
Echinococcus multilocularis jun protein 0.0088 0.0231 0.0258
Trichomonas vaginalis D-aminoacylase, putative 0.0043 0.0065 0.0145
Brugia malayi Nuclear hormone receptor-like 1 0.0107 0.03 0.067
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0107 0.03 0.03
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0148 0.0452 0.0508
Schistosoma mansoni tubulin subunit beta 0.043 0.1497 0.1508
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0035 0.0035 0.0032
Schistosoma mansoni amine GPCR 0.0308 0.1043 0.105
Echinococcus multilocularis serotonin receptor 0.0308 0.1043 0.1177
Loa Loa (eye worm) glutamate receptor 1 0.0032 0.0022 0.0028
Loa Loa (eye worm) hypothetical protein 0.0308 0.1043 0.2378
Loa Loa (eye worm) hypothetical protein 0.0308 0.1043 0.2378
Echinococcus multilocularis jumonji domain containing protein 0.0049 0.0086 0.0093
Trypanosoma brucei aurora B kinase 0.0059 0.0123 0.0174
Echinococcus multilocularis dro:myosuppressin receptor 0.0308 0.1043 0.1177
Trichomonas vaginalis conserved hypothetical protein 0.0246 0.0814 0.3057
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0054 0.0105 0.0301
Schistosoma mansoni glutamate receptor NMDA 0.0048 0.0082 0.0079
Chlamydia trachomatis ribonucleoside-diphosphate reductase subunit alpha 0.0083 0.021 0.029
Onchocerca volvulus 0.0201 0.065 0.276
Loa Loa (eye worm) hypothetical protein 0.0068 0.0157 0.0339
Schistosoma mansoni jumonji/arid domain-containing protein 0.0043 0.0062 0.0059
Onchocerca volvulus 0.0308 0.1043 0.4454
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0086 0.0224 0.0249
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0119 0.0343 0.1942
Echinococcus multilocularis deoxyribonuclease ii 0.008 0.0199 0.0222
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.01 0.0274 0.061
Schistosoma mansoni tyrosine kinase 0.0044 0.0067 0.0065
Loa Loa (eye worm) hypothetical protein 0.0308 0.1043 0.2378
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0046 0.0074 0.0149
Onchocerca volvulus 0.0058 0.012 0.0477
Loa Loa (eye worm) hypothetical protein 0.0148 0.0452 0.1019
Loa Loa (eye worm) hypothetical protein 0.005 0.0091 0.0188
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0148 0.0452 0.1019
Treponema pallidum ribonucleotide-diphosphate reductase subunit alpha 0.0083 0.021 1
Loa Loa (eye worm) hypothetical protein 0.005 0.0091 0.0188
Echinococcus multilocularis 0.0933 0.336 0.3801
Trichomonas vaginalis conserved hypothetical protein 0.0054 0.0105 0.0301
Trypanosoma cruzi WLM domain containing protein, putative 0.0046 0.0074 0.0061
Echinococcus multilocularis proprotein convertase subtilisin:kexin type 5 0.0727 0.2598 0.2938
Schistosoma mansoni site-1 peptidase (S08 family) 0.0054 0.0105 0.0103
Schistosoma mansoni hypothetical protein 0.0058 0.012 0.0118
Trichomonas vaginalis glucosylceramidase, putative 0.0167 0.0523 0.1928
Schistosoma mansoni tubulin subunit beta 0.043 0.1497 0.1508
Brugia malayi nuclear hormone receptor family member odr-7 0.005 0.0091 0.0189
Echinococcus multilocularis neuropeptide Y receptor 0.0308 0.1043 0.1177
Echinococcus granulosus glutamate receptor subunit protein glur 0.0032 0.0022 0.0021
Echinococcus granulosus glycine receptor subunit alpha 1 0.0148 0.0452 0.0508
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0107 0.03 0.067
Echinococcus granulosus rhodopsin orphan GPCR 0.0308 0.1043 0.1177
Brugia malayi ecdysone receptor 0.005 0.0091 0.0189
Schistosoma mansoni steroid hormone receptor ad4bp 0.0107 0.03 0.03
Loa Loa (eye worm) hypothetical protein 0.0057 0.0113 0.024
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0048 0.0082 0.0089
Loa Loa (eye worm) hypothetical protein 0.0308 0.1043 0.2378
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0059 0.0123 0.0276
Loa Loa (eye worm) hypothetical protein 0.0086 0.0222 0.049
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0107 0.03 0.067
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0088 0.0231 0.0258
Schistosoma mansoni hypothetical protein 0.0078 0.0194 0.0193
Entamoeba histolytica hypothetical protein 0.0038 0.0045 0.002
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0321 0.1093 0.1235
Loa Loa (eye worm) hypothetical protein 0.0308 0.1043 0.2378
Loa Loa (eye worm) hypothetical protein 0.0107 0.03 0.067
Echinococcus granulosus microtubule associated protein 2 0.0833 0.299 0.3382
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0148 0.0452 0.1019
Echinococcus multilocularis Peptidase S8 S53, subtilisin kexin sedolisin 0.0054 0.0105 0.0115
Brugia malayi larval opioid receptor 0.0308 0.1043 0.2378
Onchocerca volvulus 0.0191 0.0612 0.2596
Echinococcus granulosus neuroendocrine convertase 2 0.0751 0.2686 0.3037
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0115 0.0331 0.0371
Brugia malayi Trypsin-like protease protein 5 0.0135 0.0403 0.0906
Brugia malayi nuclear receptor NHR-67 0.005 0.0091 0.0189
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0363 0.125 0.8273
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0127 0.0376 0.0422
Echinococcus granulosus ribonucleoside diphosphate reductase large 0.0083 0.021 0.0234
Echinococcus multilocularis rhodopsin orphan GPCR 0.0308 0.1043 0.1177
Loa Loa (eye worm) hypothetical protein 0.008 0.02 0.0438
Schistosoma mansoni nuclear hormone receptor 0.0107 0.03 0.03
Echinococcus multilocularis Nuclear hormone receptor HR96 0.005 0.0091 0.01
Echinococcus granulosus epidermal growth factor receptor 0.0321 0.1093 0.1235
Loa Loa (eye worm) tubulin beta-1 chain 0.043 0.1497 0.3422
Echinococcus multilocularis ecdysone induced protein 78C 0.0107 0.03 0.0336
Onchocerca volvulus 0.0129 0.0381 0.1602
Brugia malayi putative neuropeptide receptor 0.0308 0.1043 0.2378
Schistosoma mansoni integrin beta subunit 0.0184 0.0586 0.0588
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0054 0.0105 0.0301
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0146 0.0444 0.0445
Toxoplasma gondii hypothetical protein 0.0201 0.065 0.065
Loa Loa (eye worm) hypothetical protein 0.0308 0.1043 0.2378
Schistosoma mansoni hypothetical protein 0.0198 0.0637 0.064
Toxoplasma gondii subtilisin SUB5 0.0054 0.0105 0.0105
Echinococcus granulosus SWI:SNF matrix associated 0.0129 0.0381 0.0428
Loa Loa (eye worm) hypothetical protein 0.0148 0.0452 0.1019
Trypanosoma brucei calpain, putative 0.0119 0.0343 0.0832
Schistosoma mansoni serine-type protease inhibitor 0.2702 0.9908 1
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0054 0.0105 0.0301
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0054 0.0105 0.0301
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.004 0.0053 0.0057
Onchocerca volvulus 0.0201 0.065 0.276
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0727 0.2598 1
Loa Loa (eye worm) hypothetical protein 0.0135 0.0403 0.0906
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0308 0.1043 0.105
Echinococcus granulosus integrin alpha ps 0.0137 0.0412 0.0463
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.008 0.02 0.0438
Echinococcus multilocularis G protein coupled receptor 139 0.0308 0.1043 0.1177
Schistosoma mansoni nAChR subunit 0.0148 0.0452 0.0453
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0048 0.0082 0.0089
Loa Loa (eye worm) hypothetical protein 0.0308 0.1043 0.2378
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0294 0.0994 0.1121
Loa Loa (eye worm) hypothetical protein 0.0308 0.1043 0.2378
Schistosoma mansoni hypothetical protein 0.0129 0.0381 0.0382
Onchocerca volvulus 0.0039 0.0049 0.017
Loa Loa (eye worm) hypothetical protein 0.0057 0.0113 0.024
Brugia malayi protein-tyrosine kinase 0.004 0.0053 0.0101
Schistosoma mansoni neuropeptide receptor 0.0308 0.1043 0.105
Echinococcus multilocularis bone morphogenetic protein 2 0.0032 0.0024 0.0023
Toxoplasma gondii subtilisin SUB6 0.0054 0.0105 0.0105
Schistosoma mansoni retinoic acid receptor RXR 0.0107 0.03 0.03
Loa Loa (eye worm) hypothetical protein 0.0148 0.0452 0.1019
Toxoplasma gondii PAN domain-containing protein 0.0201 0.065 0.065
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0054 0.0105 0.0301
Echinococcus granulosus Tubulin beta 2C chain 0.043 0.1497 0.1691
Trypanosoma cruzi Zn-finger in Ran binding protein and others, putative 0.0046 0.0074 0.0061
Trichomonas vaginalis glucosylceramidase, putative 0.0255 0.0848 0.3191
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0107 0.03 0.067
Loa Loa (eye worm) hypothetical protein 0.0057 0.0113 0.024
Echinococcus granulosus rhodopsin orphan GPCR 0.0308 0.1043 0.1177
Trypanosoma brucei Replication factor A protein 1 0.0049 0.0087 0.0065
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0119 0.0343 0.0832
Toxoplasma gondii microneme protein MIC17A 0.0201 0.065 0.065
Onchocerca volvulus 0.0043 0.0065 0.0241
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.005 0.0091 0.01
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0308 0.1043 0.105
Brugia malayi PAN domain containing protein 0.0201 0.065 0.1474
Leishmania major beta tubulin 0.043 0.1497 1
Brugia malayi celfurPC protein 0.0933 0.336 0.7707
Loa Loa (eye worm) hypothetical protein 0.0101 0.0278 0.0619
Loa Loa (eye worm) hypothetical protein 0.0308 0.1043 0.2378
Onchocerca volvulus 0.0308 0.1043 0.4454
Brugia malayi Nuclear hormone receptor E75 0.005 0.0091 0.0189
Trypanosoma brucei beta tubulin 0.043 0.1497 0.4283
Plasmodium falciparum plasmepsin VI 0.0047 0.008 0.0309
Echinococcus granulosus rhodopsin orphan GPCR 0.0308 0.1043 0.1177
Schistosoma mansoni tripeptidyl-peptidase II (S08 family) 0.0054 0.0105 0.0103
Loa Loa (eye worm) hypothetical protein 0.0308 0.1043 0.2378
Echinococcus granulosus g protein coupled receptor 0.0308 0.1043 0.1177
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0308 0.1043 0.2378
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.02 0.0643 0.0724
Brugia malayi Protein kinase domain containing protein 0.0095 0.0257 0.057
Echinococcus granulosus Tubulin beta 2C chain 0.043 0.1497 0.1691
Trichomonas vaginalis conserved hypothetical protein 0.0246 0.0814 0.3057
Loa Loa (eye worm) hypothetical protein 0.0057 0.0113 0.024
Loa Loa (eye worm) hypothetical protein 0.0308 0.1043 0.2378
Echinococcus multilocularis tubulin subunit beta 0.043 0.1497 0.1691
Schistosoma mansoni chromobox protein 0.0084 0.0216 0.0215
Loa Loa (eye worm) hypothetical protein 0.0201 0.065 0.1474
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.005 0.0091 0.0353
Entamoeba histolytica protein kinase, putative 0.0059 0.0123 0.0276
Loa Loa (eye worm) hypothetical protein 0.0308 0.1043 0.2378
Trypanosoma brucei variant surface glycoprotein (VSG), putative 0.0119 0.0343 0.0832
Loa Loa (eye worm) TK/EGFR protein kinase 0.0735 0.2625 0.6017
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0078 0.0194 0.0216
Loa Loa (eye worm) hypothetical protein 0.0308 0.1043 0.2378
Plasmodium falciparum subtilisin-like protease 3 0.0054 0.0105 0.0483
Brugia malayi Trypsin family protein 0.0655 0.233 0.5339
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0059 0.0123 0.0136
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.011 0.0312 0.0698
Loa Loa (eye worm) kelch domain-containing protein family protein 0.0058 0.0121 0.0256
Trichomonas vaginalis tubulin epsilon chain, putative 0.043 0.1497 0.5716
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0054 0.0105 0.0301
Loa Loa (eye worm) hypothetical protein 0.005 0.0091 0.0188
Trichomonas vaginalis conserved hypothetical protein 0.0054 0.0105 0.0301
Leishmania major beta tubulin 0.043 0.1497 1
Trichomonas vaginalis conserved hypothetical protein 0.0246 0.0814 0.3057
Loa Loa (eye worm) hypothetical protein 0.005 0.0091 0.0187
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0308 0.1043 0.2378
Brugia malayi G-protein coupled receptor 0.0308 0.1043 0.2378
Plasmodium vivax plasmepsin IV, putative 0.0047 0.008 0.0309
Loa Loa (eye worm) hypothetical protein 0.0308 0.1043 0.2378
Echinococcus granulosus lysine specific demethylase 5A 0.0043 0.0062 0.0067
Loa Loa (eye worm) hypothetical protein 0.0046 0.0074 0.0149
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0308 0.1043 0.105
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0034 0.0029 0.0029
Echinococcus multilocularis chromobox protein 1 0.0084 0.0216 0.0241
Mycobacterium ulcerans hypothetical protein 0.0863 0.31 1
Echinococcus granulosus ring and YY1 binding protein 0.0046 0.0074 0.008
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.008 0.02 0.0438
Loa Loa (eye worm) hypothetical protein 0.005 0.0091 0.0188
Echinococcus multilocularis glycine receptor subunit beta 0.0148 0.0452 0.0508
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.005 0.0091 0.0353
Schistosoma mansoni furin-1 (S08 family) 0.0506 0.1776 0.179
Plasmodium falciparum plasmepsin IV 0.0047 0.008 0.0309
Brugia malayi nuclear receptor NHR-88 0.005 0.0091 0.0189
Schistosoma mansoni TRABID protein (C64 family) 0.0046 0.0074 0.0071
Loa Loa (eye worm) hypothetical protein 0.005 0.0091 0.0188
Trichomonas vaginalis glucosylceramidase, putative 0.0255 0.0848 0.3191
Schistosoma mansoni opsin-like receptor 0.0308 0.1043 0.105
Loa Loa (eye worm) hypothetical protein 0.0476 0.1665 0.381
Echinococcus granulosus membrane associated guanylate kinase, WW and PDZ 0.005 0.0091 0.0099
Brugia malayi Deoxyribonuclease II family protein 0.008 0.0199 0.0436
Trichomonas vaginalis conserved hypothetical protein 0.0054 0.0105 0.0301
Mycobacterium ulcerans glutamine-binding lipoprotein GlnH 0.0081 0.0205 0.0564
Echinococcus granulosus tyrosine protein kinase HCK 0.0036 0.0039 0.004
Echinococcus multilocularis nmda type glutamate receptor 0.0113 0.0322 0.0361
Onchocerca volvulus 0.0201 0.065 0.276
Onchocerca volvulus 0.0148 0.0452 0.1908
Brugia malayi G protein-coupled receptor F59B2.13 0.0308 0.1043 0.2378
Echinococcus granulosus neuropeptide Y receptor 0.0308 0.1043 0.1177
Echinococcus multilocularis integrin beta 2 0.0232 0.0762 0.0859
Echinococcus multilocularis transmembrane protease serine 3 0.0135 0.0403 0.0453
Leishmania major hypothetical protein, conserved 0.0089 0.0232 0.1169
Trypanosoma cruzi hypothetical protein, conserved 0.0046 0.0074 0.0061
Schistosoma mansoni hypothetical protein 0.0308 0.1043 0.105
Trichomonas vaginalis AGC family protein kinase 0.0059 0.0123 0.0372
Onchocerca volvulus 0.0043 0.0065 0.0241
Loa Loa (eye worm) hypothetical protein 0.0655 0.233 0.5339
Echinococcus multilocularis nAChR subunit 0.0148 0.0452 0.0508
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0308 0.1043 0.1177
Brugia malayi phosphoinositide-dependent protein kinase I 0.01 0.0274 0.061
Echinococcus multilocularis serotonin receptor 0.0308 0.1043 0.1177
Toxoplasma gondii microneme protein MIC4 0.0201 0.065 0.065
Loa Loa (eye worm) GABA receptor subunit 0.008 0.02 0.0438
Schistosoma mansoni ATP-binding cassette transporter 0.0032 0.0022 0.0019
Brugia malayi Transforming growth factor beta like domain containing protein 0.0032 0.0024 0.0033
Loa Loa (eye worm) PAN domain-containing protein 0.0201 0.065 0.1474
Plasmodium falciparum plasmepsin I 0.0047 0.008 0.0309
Onchocerca volvulus 0.0068 0.0157 0.0636
Loa Loa (eye worm) hypothetical protein 0.0308 0.1043 0.2378
Loa Loa (eye worm) LGC-31 protein 0.0148 0.0452 0.1019
Loa Loa (eye worm) hypothetical protein 0.0308 0.1043 0.2378
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0059 0.0123 0.0276
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0308 0.1043 0.2378
Schistosoma mansoni tyrosine kinase 0.0315 0.1069 0.1076
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0135 0.0403 0.0404
Mycobacterium tuberculosis Conserved protein 0.0043 0.0065 0.0165
Loa Loa (eye worm) hypothetical protein 0.0054 0.0105 0.0221
Brugia malayi hypothetical protein 0.0308 0.1043 0.2378
Loa Loa (eye worm) proprotein convertase 2 0.03 0.1014 0.2312
Brugia malayi Furin-like cysteine rich region family protein 0.0735 0.2625 0.6017
Echinococcus granulosus chromobox protein 1 0.0084 0.0216 0.0241
Brugia malayi chromobox protein homolog 3 0.0047 0.0079 0.016
Trypanosoma cruzi subtilisin-like serine peptidase, putative 0.0065 0.0146 0.0563
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0308 0.1043 0.105
Loa Loa (eye worm) neuropeptide F receptor 0.0308 0.1043 0.2378
Loa Loa (eye worm) nuclear hormone receptor 0.005 0.0091 0.0188
Brugia malayi Tubulin beta-1 chain 0.043 0.1497 0.3422
Loa Loa (eye worm) hypothetical protein 0.0071 0.0169 0.0367
Loa Loa (eye worm) hypothetical protein 0.0308 0.1043 0.2378
Echinococcus multilocularis peregrin 0.0035 0.0035 0.0036
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0148 0.0452 0.0508
Schistosoma mansoni tubulin subunit beta 0.043 0.1497 0.1508
Echinococcus multilocularis neuropeptides capa receptor 0.0308 0.1043 0.1177
Schistosoma mansoni brg-1 associated factor 0.0129 0.0381 0.0382
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0107 0.03 0.03
Toxoplasma gondii ABC1 family protein 0.0043 0.0065 0.0065
Onchocerca volvulus 0.0148 0.0452 0.1908
Echinococcus granulosus transmembrane protease serine 3 0.0135 0.0403 0.0453
Trichomonas vaginalis tubulin, putative 0.043 0.1497 0.5716
Loa Loa (eye worm) TK/EPH protein kinase 0.025 0.083 0.1888
Echinococcus multilocularis neuroendocrine convertase 2 0.0751 0.2686 0.3037
Loa Loa (eye worm) hypothetical protein 0.0046 0.0074 0.0149
Brugia malayi replication factor A 73 kDa subunit 0.0103 0.0285 0.0636
Loa Loa (eye worm) hypothetical protein 0.0052 0.0095 0.0197
Mycobacterium ulcerans esterase/lipase LipP 0.0043 0.0065 0.0108
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0308 0.1043 0.1177
Brugia malayi beta-lactamase family protein 0.0043 0.0065 0.0129
Echinococcus granulosus fmrfamide receptor 0.0308 0.1043 0.1177
Brugia malayi SWIB/MDM2 domain containing protein 0.0129 0.0381 0.0856
Echinococcus granulosus proprotein convertase subtilisin:kexin type 5 0.0727 0.2598 0.2938
Schistosoma mansoni glutamate receptor kainate 0.0032 0.0022 0.0019
Brugia malayi hypothetical protein 0.0068 0.0157 0.034
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0107 0.03 0.067
Echinococcus granulosus jun protein 0.0088 0.0231 0.0258
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0058 0.012 0.0255
Chlamydia trachomatis DNA topoisomerase I 0.0129 0.0381 1
Brugia malayi Angiotensin-converting enzyme family protein 0.1203 0.4357 1
Onchocerca volvulus 0.0655 0.233 1
Trichomonas vaginalis proprotein convertase subtilisin/kexin type, putative 0.0246 0.0814 0.3057
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0043 0.0065 0.0129
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0054 0.0105 0.0301
Echinococcus granulosus glycine receptor subunit alpha 1 0.0148 0.0452 0.0508
Trypanosoma brucei beta tubulin 0.043 0.1497 0.4283
Toxoplasma gondii subtilisin SUB1 0.0054 0.0105 0.0105
Loa Loa (eye worm) hypothetical protein 0.0043 0.0065 0.0129
Echinococcus granulosus insulin receptor 0.0192 0.0616 0.0694
Brugia malayi Latrophilin receptor protein 2 0.0078 0.0194 0.0426
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0044 0.0067 0.0072
Loa Loa (eye worm) hypothetical protein 0.0107 0.03 0.067
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0054 0.0105 0.0301
Echinococcus granulosus dnaJ subfamily B 0.0415 0.1442 0.1629
Loa Loa (eye worm) glutamate receptor 2 0.0032 0.0022 0.0028
Trichomonas vaginalis D-aminoacylase, putative 0.0043 0.0065 0.0145
Loa Loa (eye worm) PAN domain-containing protein 0.0201 0.065 0.1474
Echinococcus multilocularis Furin 1 0.03 0.1014 0.1145
Leishmania major beta tubulin 0.043 0.1497 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0308 0.1043 0.105
Echinococcus multilocularis beta tubulin 0.043 0.1497 0.1691
Toxoplasma gondii PAN domain-containing protein 0.0201 0.065 0.065
Loa Loa (eye worm) hypothetical protein 0.0046 0.0074 0.0149
Leishmania major beta tubulin 0.043 0.1497 1
Trichomonas vaginalis glucosylceramidase, putative 0.0176 0.0557 0.2058
Loa Loa (eye worm) hypothetical protein 0.0201 0.065 0.1474
Schistosoma mansoni serine/threonine protein kinase 0.01 0.0274 0.0274
Schistosoma mansoni myosin xvIII 0.0308 0.1043 0.105
Brugia malayi beta-lactamase family protein 0.0043 0.0065 0.0129
Schistosoma mansoni jumonji/arid domain-containing protein 0.0043 0.0062 0.0059
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0054 0.0105 0.0301
Echinococcus granulosus jumonji domain containing protein 0.0049 0.0086 0.0093
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0294 0.0994 0.2264
Loa Loa (eye worm) hypothetical protein 0.0068 0.0157 0.0339
Loa Loa (eye worm) replication factor A 73 kDa subunit 0.0103 0.0285 0.0635
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0148 0.0452 0.1019
Echinococcus granulosus survival motor neuron protein 1 0.0286 0.0962 0.1085
Echinococcus granulosus nuclear receptor 2DBD gamma 0.005 0.0091 0.01
Loa Loa (eye worm) hypothetical protein 0.0135 0.0403 0.0906
Echinococcus multilocularis neuropeptides capa receptor 0.0308 0.1043 0.1177
Echinococcus granulosus GPCR family 2 0.0078 0.0194 0.0216
Brugia malayi Dopamine receptor protein 2 0.0308 0.1043 0.2378
Echinococcus granulosus dro:myosuppressin receptor 0.0308 0.1043 0.1177
Loa Loa (eye worm) hypothetical protein 0.0043 0.0065 0.0129
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.0068 0.0157 0.0174
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0308 0.1043 0.2378
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.0177 0.0561 0.1268
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0107 0.03 0.067
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.005 0.0091 0.01
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0107 0.03 0.067
Schistosoma mansoni tubulin subunit beta 0.043 0.1497 0.1508
Loa Loa (eye worm) hypothetical protein 0.008 0.02 0.0438
Trypanosoma brucei subtilisin peptidase 0.0054 0.0105 0.0119
Schistosoma mansoni hypothetical protein 0.0089 0.0232 0.0232
Schistosoma mansoni neuropeptide receptor 0.0308 0.1043 0.105
Entamoeba histolytica hypothetical protein 0.008 0.02 0.0525
Schistosoma mansoni nAChR subunit 0.0148 0.0452 0.0453
Loa Loa (eye worm) hypothetical protein 0.0035 0.0035 0.0058
Leishmania major beta tubulin 0.043 0.1497 1
Onchocerca volvulus Segment polarity protein dishevelled homolog 0.0058 0.0119 0.0473
Echinococcus multilocularis NMDA receptor 0.0032 0.0022 0.0021
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0054 0.0105 0.0301
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0255 0.0848 0.1929
Echinococcus multilocularis dnaJ subfamily B 0.0415 0.1442 0.1629
Onchocerca volvulus 0.0308 0.1043 0.4454
Loa Loa (eye worm) beta-lactamase 0.0043 0.0065 0.0129
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0119 0.0343 0.0832
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0308 0.1043 0.105
Entamoeba histolytica hypothetical protein 0.0038 0.0045 0.002
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0363 0.125 0.2853
Schistosoma mansoni hypothetical protein 0.0101 0.0278 0.0278
Brugia malayi Dopamine receptor protein 1 0.0308 0.1043 0.2378
Echinococcus granulosus tyrosine protein kinase Src42A 0.0034 0.0029 0.0029
Mycobacterium tuberculosis Probable alanine and proline rich membrane-anchored mycosin MycP2 (serine protease) (subtilisin-like protease) (subtilase-like) 0.0054 0.0105 0.0295
Brugia malayi putative neuropeptide receptor NPR1 0.0308 0.1043 0.2378
Plasmodium vivax ribonucleoside-diphosphate reductase large chain, putative 0.0083 0.021 0.12
Loa Loa (eye worm) hypothetical protein 0.0148 0.0452 0.1019
Echinococcus granulosus neuropeptide FF receptor 2 0.0546 0.1925 0.2175
Trichomonas vaginalis AGC family protein kinase 0.01 0.0274 0.0959
Echinococcus multilocularis tissue type plasminogen activator 0.0089 0.0232 0.026
Echinococcus multilocularis beta tubulin 0.043 0.1497 0.1691
Echinococcus multilocularis FTZ F1 alpha 0.0107 0.03 0.0336
Loa Loa (eye worm) hypothetical protein 0.0148 0.0452 0.1019
Trichomonas vaginalis esterase, putative 0.0043 0.0065 0.0145
Toxoplasma gondii aspartyl protease ASP1 0.0047 0.008 0.008
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0107 0.03 0.0336
Echinococcus multilocularis Nuclear hormone receptor HR96 0.005 0.0091 0.01
Schistosoma mansoni microtubule-associated protein tau 0.0833 0.299 0.3015
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0148 0.0452 0.1019
Trichomonas vaginalis chromobox protein, putative 0.0051 0.0092 0.025
Echinococcus multilocularis Nuclear pore complex protein Nup153 0.0046 0.0074 0.008
Loa Loa (eye worm) hypothetical protein 0.005 0.0091 0.0188
Loa Loa (eye worm) acetylcholine receptor protein 0.0068 0.0157 0.0339
Brugia malayi RE15519p 0.0308 0.1043 0.2378
Echinococcus granulosus alpha 1A adrenergic receptor 0.0308 0.1043 0.1177
Schistosoma mansoni hypothetical protein 0.0308 0.1043 0.105
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.03 0.1014 0.3839
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.005 0.0091 0.01
Loa Loa (eye worm) hypothetical protein 0.0201 0.065 0.1474
Schistosoma mansoni amine GPCR 0.0308 0.1043 0.105
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0119 0.0343 0.1942
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0308 0.1043 0.2378
Loa Loa (eye worm) hypothetical protein 0.0308 0.1043 0.2378
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.0068 0.0157 0.0174
Trypanosoma brucei RNA helicase, putative 0.0946 0.3408 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0308 0.1043 0.1177
Echinococcus multilocularis nuclear receptor nhr 48 0.005 0.0091 0.01
Brugia malayi brahma associated protein 60 kDa 0.0129 0.0381 0.0856
Leishmania major beta tubulin 0.043 0.1497 1
Schistosoma mansoni jun-related protein 0.0072 0.017 0.0168
Echinococcus multilocularis SWI:SNF matrix associated 0.0129 0.0381 0.0428
Echinococcus multilocularis glutamate receptor subunit protein glur 0.0032 0.0022 0.0021
Trichomonas vaginalis glucosylceramidase, putative 0.0255 0.0848 0.3191
Trypanosoma brucei C-8 sterol isomerase, putative 0.0363 0.125 0.3544
Onchocerca volvulus 0.003 0.0017 0.0034
Echinococcus multilocularis Upstream activation factor subunit UAF30 0.0129 0.0381 0.0428
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.008 0.02 0.0198
Onchocerca volvulus Alhambra homolog 0.0035 0.0035 0.0109
Brugia malayi hypothetical protein 0.0069 0.0161 0.0349
Brugia malayi Integrin beta pat-3 precursor 0.0313 0.1062 0.2421
Loa Loa (eye worm) hypothetical protein 0.0308 0.1043 0.2378
Loa Loa (eye worm) hypothetical protein 0.0286 0.0962 0.2191
Echinococcus granulosus PHD finger protein rhinoceros 0.0035 0.0035 0.0036
Schistosoma mansoni tgf-beta family 0.0032 0.0024 0.0021
Loa Loa (eye worm) hypothetical protein 0.005 0.0091 0.0188
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0308 0.1043 0.105
Schistosoma mansoni neuropeptide F-like receptor 0.0308 0.1043 0.105
Echinococcus granulosus allatostatin A receptor 0.0308 0.1043 0.1177
Brugia malayi PAN domain containing protein 0.0201 0.065 0.1474
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0308 0.1043 0.1177
Leishmania major beta tubulin 0.043 0.1497 1
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0119 0.0343 0.0832
Loa Loa (eye worm) hypothetical protein 0.0186 0.0592 0.134
Onchocerca volvulus 0.0135 0.0403 0.1697
Echinococcus multilocularis neuropeptide Y receptor 0.0308 0.1043 0.1177
Schistosoma mansoni cercarial elastase (S01 family) 0.0135 0.0403 0.0404
Brugia malayi beta-lactamase 0.0043 0.0065 0.0129
Schistosoma mansoni survival motor neuron protein 0.0058 0.012 0.0118
Echinococcus granulosus 3'partial|membrane associated guanylate kinase ww and pdz 0.005 0.0091 0.0099
Loa Loa (eye worm) neuropeptide F receptor 0.0308 0.1043 0.2378
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0054 0.0105 0.0301
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0051 0.0092 0.0357
Echinococcus granulosus tm gpcr rhodopsin 0.2412 0.8835 1
Mycobacterium ulcerans beta-lactamase 0.0043 0.0065 0.0108
Loa Loa (eye worm) hypothetical protein 0.0097 0.0264 0.0587
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.0198 0.0637 0.0717
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0107 0.03 0.0336
Echinococcus multilocularis neuropeptide FF receptor 2 0.0546 0.1925 0.2175
Mycobacterium ulcerans hypothetical protein 0.0043 0.0065 0.0108
Brugia malayi nuclear receptor RXR 0.005 0.0091 0.0189
Schistosoma mansoni hypothetical protein 0.0415 0.1442 0.1453
Loa Loa (eye worm) hypothetical protein 0.0035 0.0032 0.0053
Echinococcus granulosus 7TM GPCR rhodopsin 0.0308 0.1043 0.1177
Loa Loa (eye worm) hypothetical protein 0.0191 0.0612 0.1386
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0044 0.0067 0.0072
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0107 0.03 0.1254
Mycobacterium ulcerans membrane-anchored mycosin MycP3 0.0054 0.0105 0.0238
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0048 0.0082 0.0089
Leishmania major beta tubulin 0.043 0.1497 1
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0068 0.0157 0.034
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0119 0.0343 0.1942
Echinococcus granulosus Ribosomal protein S1 RNA binding domain 0.0032 0.0022 0.0021
Echinococcus granulosus Nuclear pore complex protein Nup153 0.0046 0.0074 0.008
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0308 0.1043 0.1177
Loa Loa (eye worm) hypothetical protein 0.0148 0.0452 0.1019
Schistosoma mansoni neurotransmitter gated ion channel 0.008 0.02 0.0198
Echinococcus granulosus tyrosine protein kinase Lyn 0.0046 0.0075 0.0081
Loa Loa (eye worm) hypothetical protein 0.0068 0.0157 0.0339
Echinococcus multilocularis segment polarity protein dishevelled 0.0098 0.0269 0.0301
Onchocerca volvulus 0.0046 0.0074 0.0279
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0294 0.0994 0.1121
Schistosoma mansoni tgf-beta family 0.0032 0.0024 0.0021
Schistosoma mansoni hypothetical protein 0.0129 0.0381 0.0382
Brugia malayi Heterochromatin protein 1 0.0084 0.0216 0.0475
Loa Loa (eye worm) subtilase 0.0054 0.0105 0.0221
Loa Loa (eye worm) hypothetical protein 0.0107 0.03 0.067
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.005 0.0091 0.0189
Onchocerca volvulus 0.0476 0.1665 0.7135
Schistosoma mansoni nuclear hormone receptor 0.005 0.0091 0.0089
Schistosoma mansoni membrane associated guanylate kinase inverted related 0.007 0.0162 0.016
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0727 0.2598 1
Onchocerca volvulus 0.008 0.02 0.082
Plasmodium falciparum cysteine repeat modular protein 1 0.0089 0.0232 0.1354
Loa Loa (eye worm) LjBmp2/4b 0.0032 0.0024 0.0033
Loa Loa (eye worm) PAN domain-containing protein 0.0201 0.065 0.1474
Echinococcus granulosus glutamate receptor 2 0.0048 0.0082 0.0089
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0148 0.0452 0.1019
Loa Loa (eye worm) hypothetical protein 0.0068 0.0157 0.0339
Echinococcus granulosus replication protein A 70 kDa DNA binding 0.0103 0.0285 0.032
Onchocerca volvulus Putative replication factor A 73 kDa subunit 0.0092 0.0245 0.1018
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0107 0.03 0.067
Echinococcus granulosus thyroid hormone receptor alpha 0.005 0.0091 0.01
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.2412 0.8835 1
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0057 0.0113 0.0111
Schistosoma mansoni tubulin subunit beta 0.043 0.1497 0.1508
Schistosoma mansoni protein kinase 0.0127 0.0376 0.0376
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0308 0.1043 0.1177
Schistosoma mansoni neuropeptide receptor 0.0308 0.1043 0.105
Echinococcus multilocularis rhodopsin orphan GPCR 0.0308 0.1043 0.1177
Loa Loa (eye worm) apoptosis regulator protein 0.0198 0.0637 0.1443
Onchocerca volvulus 0.0308 0.1043 0.4454
Onchocerca volvulus 0.005 0.0091 0.0353
Brugia malayi hypothetical protein 0.0057 0.0113 0.024
Echinococcus multilocularis membrane bound transcription factor site 1 0.0054 0.0105 0.0115
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0107 0.03 0.0336
Trypanosoma brucei hypothetical protein, conserved 0.0046 0.0074 0.0026
Loa Loa (eye worm) hypothetical protein 0.0308 0.1043 0.2378
Onchocerca volvulus 0.0308 0.1043 0.4454
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0308 0.1043 0.105
Schistosoma mansoni cercarial elastase (S01 family) 0.0135 0.0403 0.0404
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0148 0.0452 0.0453
Echinococcus granulosus Mastin 0.0135 0.0403 0.0453
Loa Loa (eye worm) hypothetical protein 0.008 0.02 0.0438
Leishmania major beta tubulin 0.043 0.1497 1
Brugia malayi orphan nuclear receptor NR2E1 0.005 0.0091 0.0189
Loa Loa (eye worm) jmjC domain-containing protein 0.0043 0.0062 0.0121
Plasmodium vivax subtilisin-like protease 1 0.0054 0.0105 0.0483
Echinococcus granulosus zinc finger protein Ran binding 0.0046 0.0074 0.008
Schistosoma mansoni hypothetical protein 0.0035 0.0035 0.0032
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0078 0.0194 0.0426
Echinococcus multilocularis glycoprotein Antigen 5 0.0135 0.0403 0.0453
Loa Loa (eye worm) hypothetical protein 0.0308 0.1043 0.2378
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0048 0.0082 0.0089
Echinococcus granulosus integrin alpha 3 0.0235 0.0773 0.0871
Mycobacterium tuberculosis Conserved protein 0.0043 0.0065 0.0165
Trypanosoma cruzi subtilisin-like serine peptidase, putative 0.0065 0.0146 0.0563
Loa Loa (eye worm) hypothetical protein 0.0148 0.0452 0.1019
Toxoplasma gondii subtilisin SUB12 0.0256 0.0851 0.0851
Brugia malayi Transforming growth factor beta like domain containing protein 0.0032 0.0024 0.0033
Leishmania major C-8 sterol isomerase-like protein 0.0363 0.125 0.8273
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.0177 0.0561 0.0631
Onchocerca volvulus 0.0201 0.065 0.276
Onchocerca volvulus 0.0308 0.1043 0.4454
Loa Loa (eye worm) hypothetical protein 0.0068 0.0157 0.0339
Brugia malayi hypothetical protein 0.0057 0.0113 0.024
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0068 0.0157 0.034
Echinococcus multilocularis Tubulin beta 2C chain 0.043 0.1497 0.1691
Loa Loa (eye worm) tubulin beta-4 chain 0.043 0.1497 0.3422
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0107 0.03 0.03
Onchocerca volvulus 0.0046 0.0074 0.0279
Echinococcus granulosus anti dorsalizing morphogenetic protein 1a 0.0126 0.0371 0.0416
Echinococcus granulosus tumor protein p63 0.0408 0.1415 0.1599
Giardia lamblia Beta tubulin 0.043 0.1497 1
Echinococcus granulosus nuclear receptor nhr 48 0.005 0.0091 0.01
Loa Loa (eye worm) hypothetical protein 0.0107 0.03 0.067
Echinococcus granulosus nAChR subunit 0.0148 0.0452 0.0508
Onchocerca volvulus 0.0308 0.1043 0.4454
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0148 0.0452 0.1019
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0107 0.03 0.067
Loa Loa (eye worm) hypothetical protein 0.005 0.0091 0.0188
Echinococcus granulosus Tubulin beta 2C chain 0.043 0.1497 0.1691
Loa Loa (eye worm) hypothetical protein 0.0068 0.0157 0.0339
Loa Loa (eye worm) hypothetical protein 0.0308 0.1043 0.2378
Onchocerca volvulus 0.0068 0.0157 0.0636
Schistosoma mansoni protein kinase 0.0127 0.0376 0.0376
Loa Loa (eye worm) hypothetical protein 0.0201 0.065 0.1474
Onchocerca volvulus 0.0135 0.0403 0.1697
Trypanosoma cruzi beta tubulin, putative 0.043 0.1497 1
Loa Loa (eye worm) TK protein kinase 0.0036 0.0039 0.0068
Loa Loa (eye worm) brahma associated protein 0.0129 0.0381 0.0856
Schistosoma mansoni acetylcholine receptor subunit beta 0.0068 0.0157 0.0155
Trichomonas vaginalis glucosylceramidase, putative 0.0167 0.0523 0.1928
Entamoeba histolytica hypothetical protein 0.0038 0.0045 0.002
Brugia malayi map kinase activated protein kinase protein 2 0.0177 0.0561 0.1268
Onchocerca volvulus 0.0308 0.1043 0.4454
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0044 0.0067 0.0072
Brugia malayi Matrix metalloprotease, N-terminal domain containing protein 0.0035 0.0032 0.0053
Loa Loa (eye worm) steroid hormone receptor 0.0107 0.03 0.067
Loa Loa (eye worm) hypothetical protein 0.0308 0.1043 0.2378
Onchocerca volvulus 0.005 0.0091 0.0353
Loa Loa (eye worm) hypothetical protein 0.0655 0.233 0.5339
Echinococcus granulosus bone morphogenetic protein 2 0.0032 0.0024 0.0023
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0308 0.1043 0.1177
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0054 0.0105 0.0301
Schistosoma mansoni nAChR subunit 0.0148 0.0452 0.0453
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0107 0.03 0.0336
Loa Loa (eye worm) hypothetical protein 0.008 0.02 0.0438
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0294 0.0994 0.1121
Schistosoma mansoni replication factor A 1 rfa1 0.0103 0.0285 0.0285
Mycobacterium tuberculosis Probable peptidoglycan hydrolase 0.0035 0.0032 0.0058
Echinococcus multilocularis neuropeptide s receptor 0.0308 0.1043 0.1177
Schistosoma mansoni serine/threonine protein kinase 0.0059 0.0123 0.0121
Toxoplasma gondii microneme protein, putative 0.0201 0.065 0.065
Echinococcus multilocularis GPCR, family 2 0.0078 0.0194 0.0216
Echinococcus granulosus tyrosine protein kinase Blk 0.004 0.0053 0.0057
Schistosoma mansoni ribonucleoside-diphosphate reductase alpha subunit 0.0083 0.021 0.0209
Loa Loa (eye worm) hypothetical protein 0.005 0.0091 0.0188
Loa Loa (eye worm) hypothetical protein 0.0043 0.0065 0.0129
Echinococcus granulosus tm gpcr rhodopsin 0.0308 0.1043 0.1177
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0308 0.1043 0.105
Echinococcus multilocularis 0.0183 0.0583 0.0656
Loa Loa (eye worm) tubulin beta-2A chain 0.043 0.1497 0.3422
Loa Loa (eye worm) hypothetical protein 0.0135 0.0403 0.0906
Brugia malayi PAN domain containing protein 0.0201 0.065 0.1474
Brugia malayi Cation transporter family protein 0.0148 0.0452 0.1019
Onchocerca volvulus 0.0308 0.1043 0.4454
Trypanosoma cruzi hypothetical protein, conserved 0.0089 0.0232 0.1169
Brugia malayi nuclear receptor RXR 0.0057 0.0113 0.024
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0308 0.1043 0.105
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.0047 0.008 0.0087
Brugia malayi Transforming growth factor beta like domain containing protein 0.0126 0.0371 0.0832
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0044 0.0067 0.0072
Echinococcus multilocularis tubulin, beta 4A class IVa 0.043 0.1497 0.1691
Echinococcus multilocularis PHD finger protein rhinoceros 0.0035 0.0035 0.0036
Echinococcus multilocularis zinc finger protein Ran binding 0.0046 0.0074 0.008
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0655 0.233 0.235
Schistosoma mansoni serine/threonine protein kinase 0.0177 0.0561 0.0563
Echinococcus granulosus FTZ F1 alpha 0.0107 0.03 0.0336
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0127 0.0376 0.0422
Onchocerca volvulus 0.0148 0.0452 0.1908
Schistosoma mansoni nAChR subunit 0.0148 0.0452 0.0453
Brugia malayi Nuclear hormone receptor E75 0.005 0.0091 0.0189
Wolbachia endosymbiont of Brugia malayi ribonucleotide-diphosphate reductase subunit alpha 0.0083 0.021 0.5
Echinococcus multilocularis Tubulin beta 2C chain 0.043 0.1497 0.1691
Onchocerca volvulus 0.0068 0.0157 0.0636
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.0068 0.0157 0.034
Echinococcus granulosus neuropeptide receptor 0.0308 0.1043 0.1177
Echinococcus multilocularis ring and YY1 binding protein 0.0046 0.0074 0.008
Schistosoma mansoni membrane associated guanylate kinase inverted related 0.005 0.0091 0.0088
Echinococcus multilocularis integrin alpha ps 0.0066 0.0148 0.0164
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0107 0.03 0.067
Brugia malayi Integrin alpha pat-2 precursor 0.0306 0.1037 0.2365
Brugia malayi hypothetical protein 0.0308 0.1043 0.2378
Loa Loa (eye worm) hypothetical protein 0.0148 0.0452 0.1019
Trichomonas vaginalis AGC family protein kinase 0.01 0.0274 0.0959
Brugia malayi latrophilin 2 splice variant baaae 0.0101 0.0278 0.0619
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0078 0.0194 0.0216
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0048 0.0082 0.0089
Schistosoma mansoni hypothetical protein 0.0046 0.0074 0.0071
Schistosoma mansoni tyrosine kinase 0.0192 0.0616 0.0619
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0308 0.1043 0.1177
Mycobacterium tuberculosis Conserved hypothetical protein 0.0863 0.31 1
Entamoeba histolytica hypothetical protein, conserved 0.0863 0.31 1
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0308 0.1043 0.1177
Echinococcus multilocularis lysine specific demethylase 5A 0.0043 0.0062 0.0067
Echinococcus multilocularis g protein coupled receptor 0.0308 0.1043 0.1177
Loa Loa (eye worm) hypothetical protein 0.0308 0.1043 0.2378
Echinococcus granulosus neuropeptide receptor A26 0.0308 0.1043 0.1177
Brugia malayi YY1-associated factor 2 0.0046 0.0074 0.0149
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0048 0.0082 0.0089
Brugia malayi hypothetical protein 0.0308 0.1043 0.2378
Onchocerca volvulus 0.0308 0.1043 0.4454
Loa Loa (eye worm) ACC-1 protein 0.0148 0.0452 0.1019
Echinococcus multilocularis rhodopsin orphan GPCR 0.0308 0.1043 0.1177
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.0198 0.0637 0.0717
Brugia malayi Membrane-bound transcription factor site-1 protease precursor 0.0054 0.0105 0.0221
Trichomonas vaginalis AGC family protein kinase 0.0059 0.0123 0.0372
Toxoplasma gondii kringle domain-containing protein 0.0089 0.0232 0.0232
Brugia malayi hypothetical protein 0.0038 0.0045 0.0083
Brugia malayi PDZ domain containing protein 0.0052 0.0095 0.0197
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.0198 0.0637 0.064
Toxoplasma gondii PHD-finger domain-containing protein 0.0035 0.0035 0.0035
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0148 0.0452 0.1019
Loa Loa (eye worm) TK protein kinase 0.004 0.0053 0.0101
Mycobacterium tuberculosis Conserved protein 0.0863 0.31 1
Loa Loa (eye worm) angiotensin-converting enzyme family protein 0.1203 0.4357 1
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0671 0.239 0.2409
Brugia malayi SRC-1 0.0044 0.0067 0.0133
Trichomonas vaginalis conserved hypothetical protein 0.0246 0.0814 0.3057
Schistosoma mansoni dishevelled 0.0098 0.0269 0.0268
Echinococcus granulosus glutamate receptor ionotropic kainate 0.0032 0.0022 0.0021
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0107 0.03 0.0336
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0046 0.0074 0.0149
Loa Loa (eye worm) hypothetical protein 0.0308 0.1043 0.2378
Echinococcus granulosus g-protein coupled receptor 0.0308 0.1043 0.1177
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0043 0.0065 0.0063
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0119 0.0343 0.0832
Echinococcus granulosus MAP kinase activated protein kinase 2 0.0177 0.0561 0.0631
Echinococcus multilocularis allatostatin A receptor 0.0308 0.1043 0.1177
Echinococcus multilocularis membrane associated guanylate kinase, WW and PDZ 0.005 0.0091 0.0099
Loa Loa (eye worm) endoprotease bli-4 0.1179 0.4269 0.9798
Echinococcus multilocularis survival motor neuron protein 1 0.0286 0.0962 0.1085
Loa Loa (eye worm) hypothetical protein 0.0068 0.0157 0.0339
Plasmodium vivax replication protein A1, large subunit, putative 0.0049 0.0087 0.0358
Echinococcus granulosus glutamate receptor ionotropic kainate 3 0.0032 0.0022 0.0021
Echinococcus granulosus epidermal growth factor receptor 0.0735 0.2625 0.2969
Schistosoma mansoni biogenic amine (5HT) receptor 0.0308 0.1043 0.105
Loa Loa (eye worm) hypothetical protein 0.0043 0.0065 0.0129
Schistosoma mansoni hypothetical protein 0.0078 0.0194 0.0193
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.0098 0.0269 0.0598
Onchocerca volvulus 0.0308 0.1043 0.4454
Loa Loa (eye worm) hypothetical protein 0.0451 0.1576 0.3603
Echinococcus multilocularis g-protein coupled receptor 0.0308 0.1043 0.1177
Schistosoma mansoni tyrosine kinase 0.0192 0.0616 0.0619
Toxoplasma gondii Zn-finger in Ran binding protein and others domain-containing protein 0.0046 0.0074 0.0074
Echinococcus multilocularis neuropeptide receptor A26 0.0308 0.1043 0.1177
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0308 0.1043 0.4454
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0068 0.0157 0.0339
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0043 0.0065 0.0129
Trypanosoma brucei beta tubulin 0.043 0.1497 0.4283
Trypanosoma cruzi hypothetical protein, conserved 0.0046 0.0074 0.0061
Plasmodium falciparum zinc finger Ran-binding domain-containing protein 2, putative 0.0046 0.0074 0.0269
Echinococcus multilocularis insulin receptor 0.0192 0.0616 0.0694
Leishmania major hypothetical protein, conserved 0.0046 0.0074 0.0061
Loa Loa (eye worm) hypothetical protein 0.0308 0.1043 0.2378
Mycobacterium tuberculosis Probable glutamine-binding lipoprotein GlnH (GLNBP) 0.0081 0.0205 0.0618
Mycobacterium tuberculosis Probable membrane-anchored mycosin MycP4 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-4) 0.0054 0.0105 0.0295
Loa Loa (eye worm) ribonucleoside-diphosphate reductase large subunit 0.0083 0.021 0.0462
Loa Loa (eye worm) hypothetical protein 0.0169 0.0529 0.1196
Loa Loa (eye worm) hypothetical protein 0.0046 0.0074 0.0149
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0148 0.0452 0.0453
Trichomonas vaginalis tubulin epsilon chain, putative 0.043 0.1497 0.5716
Plasmodium falciparum serine/threonine protein kinase, putative 0.0059 0.0123 0.0607
Plasmodium vivax hypothetical protein, conserved 0.0043 0.0065 0.0209
Brugia malayi neuroendocrine convertase 1 precursor 0.0751 0.2686 0.6157
Loa Loa (eye worm) DR-78 0.005 0.0091 0.0188
Giardia lamblia High cysteine membrane protein Group 2 0.0428 0.1488 0.9937
Toxoplasma gondii subtilisin SUB4 0.0054 0.0105 0.0105
Echinococcus granulosus chromobox protein 1 0.0084 0.0216 0.0241
Loa Loa (eye worm) TK/ROR protein kinase 0.0095 0.0257 0.0569
Plasmodium vivax aspartyl proteinase, putative 0.0047 0.008 0.0309
Echinococcus multilocularis microtubule associated protein 2 0.0833 0.299 0.3382
Trichomonas vaginalis glucosylceramidase, putative 0.0255 0.0848 0.3191
Loa Loa (eye worm) AUR protein kinase 0.0059 0.0123 0.0263
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0308 0.1043 0.105
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0086 0.0224 0.1106
Schistosoma mansoni cercarial elastase (S01 family) 0.0135 0.0403 0.0404
Brugia malayi beta-tubulin, identical 0.043 0.1497 0.3422
Trypanosoma cruzi mitochondrial RNA binding complex 1 subunit, putative 0.0046 0.0074 0.0061
Trypanosoma brucei hypothetical protein, conserved 0.0046 0.0074 0.0026
Echinococcus multilocularis tyrosine protein kinase HCK 0.0036 0.0039 0.004
Trichomonas vaginalis chromobox protein, putative 0.0051 0.0092 0.025
Loa Loa (eye worm) hypothetical protein 0.0148 0.0452 0.1019
Toxoplasma gondii microneme protein MIC17B 0.0201 0.065 0.065
Schistosoma mansoni subfamily S8B non-peptidase homologue (S08 family) 0.03 0.1014 0.1021
Brugia malayi Serotonin receptor 0.0308 0.1043 0.2378
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0294 0.0994 0.1121
Loa Loa (eye worm) BEN-1 protein 0.043 0.1497 0.3422
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0068 0.0157 0.034
Onchocerca volvulus 0.0201 0.065 0.276
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0135 0.0403 0.0404
Loa Loa (eye worm) hypothetical protein 0.0066 0.0148 0.0318
Onchocerca volvulus Protein ultraspiracle homolog 0.0107 0.03 0.1254
Trichomonas vaginalis deoxyribonuclease II, putative 0.008 0.0199 0.0665
Loa Loa (eye worm) hypothetical protein 0.0148 0.0452 0.1019
Schistosoma mansoni hypothetical protein 0.0246 0.0814 0.0818
Loa Loa (eye worm) hypothetical protein 0.0308 0.1043 0.2378
Schistosoma mansoni deoxyribonuclease II-related 0.008 0.0199 0.0198
Onchocerca volvulus 0.0476 0.1665 0.7135
Trypanosoma cruzi Zn-finger in Ran binding protein and others/FYVE zinc finger, putative 0.0046 0.0074 0.0061
Brugia malayi nuclear hormone receptor family member nhr-6 0.005 0.0091 0.0189
Echinococcus multilocularis ephrin type A receptor 4 A 0.0198 0.0636 0.0717
Echinococcus granulosus rhodopsin orphan GPCR 0.0308 0.1043 0.1177
Loa Loa (eye worm) hypothetical protein 0.0308 0.1043 0.2378
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.0047 0.008 0.008
Toxoplasma gondii subtilisin SUB9 0.0054 0.0105 0.0105
Brugia malayi PAN domain containing protein 0.0201 0.065 0.1474
Loa Loa (eye worm) hypothetical protein 0.008 0.02 0.0438
Echinococcus granulosus beta tubulin 0.043 0.1497 0.1691
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0119 0.0343 0.0832
Trypanosoma brucei calpain-like protein, putative 0.0119 0.0343 0.0832
Echinococcus multilocularis beta LACTamase domain containing family member 0.0043 0.0065 0.007
Brugia malayi Calcitonin receptor-like protein seb-1 0.0179 0.0568 0.1286
Onchocerca volvulus 0.0089 0.0232 0.0962
Schistosoma mansoni tyrosine kinase 0.0044 0.0067 0.0065
Echinococcus multilocularis ribonucleoside diphosphate reductase large 0.0083 0.021 0.0234
Echinococcus multilocularis orexin receptor type 2 0.0308 0.1043 0.1177
Loa Loa (eye worm) hypothetical protein 0.024 0.0794 0.1804
Echinococcus multilocularis glycine receptor subunit beta 0.0148 0.0452 0.0508
Brugia malayi Nuclear hormone receptor-like 1 0.0057 0.0113 0.024
Schistosoma mansoni cercarial elastase (S01 family) 0.0135 0.0403 0.0404
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0038 0.0045 0.0047
Loa Loa (eye worm) hypothetical protein 0.0047 0.008 0.0162
Loa Loa (eye worm) hypothetical protein 0.0068 0.0157 0.0339
Echinococcus multilocularis G-protein coupled receptor, putative 0.0308 0.1043 0.1177
Schistosoma mansoni cercarial elastase (S01 family) 0.0135 0.0403 0.0404
Schistosoma mansoni subfamily S8B unassigned peptidase (S08 family) 0.1179 0.4269 0.4307
Entamoeba histolytica protein kinase , putative 0.0059 0.0123 0.0276
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0054 0.0105 0.0301
Echinococcus multilocularis rhodopsin orphan GPCR 0.0308 0.1043 0.1177
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0148 0.0452 0.0508
Schistosoma mansoni acetylcholine receptor-related 0.0068 0.0157 0.0155
Entamoeba histolytica hypothetical protein 0.0038 0.0045 0.002
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0107 0.03 0.0336
Brugia malayi proprotein convertase 2 0.0751 0.2686 0.6157
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0308 0.1043 0.105
Echinococcus multilocularis glutamate receptor 2 0.0032 0.0022 0.0021
Toxoplasma gondii PAN domain-containing protein 0.0201 0.065 0.065
Brugia malayi hypothetical protein 0.005 0.0091 0.0189
Schistosoma mansoni apoptosis regulator bax 0.0198 0.0637 0.064
Loa Loa (eye worm) G-protein coupled receptor 0.0308 0.1043 0.2378
Leishmania major subtilisin-like serine peptidase 0.0054 0.0105 0.0279
Brugia malayi brahma associated protein 60 kDa 0.0129 0.0381 0.0856
Leishmania major beta tubulin 0.043 0.1497 1
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.0047 0.008 0.0087
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0048 0.0082 0.0089
Onchocerca volvulus 0.0308 0.1043 0.4454
Onchocerca volvulus 0.0476 0.1665 0.7135
Trichomonas vaginalis glucosylceramidase, putative 0.0167 0.0523 0.1928
Trichomonas vaginalis AGC family protein kinase 0.01 0.0274 0.0959
Brugia malayi ORL1-like opioid receptor 0.0308 0.1043 0.2378
Brugia malayi steroid hormone receptor 0.0107 0.03 0.067
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.152 0.5531 0.6258
Schistosoma mansoni biogenic amine receptor 0.0308 0.1043 0.105
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0135 0.0403 0.0453
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0068 0.0157 0.034
Schistosoma mansoni tyrosine kinase 0.0315 0.1069 0.1076
Loa Loa (eye worm) hypothetical protein 0.0148 0.0452 0.1019
Schistosoma mansoni nuclear receptor 0.005 0.0091 0.0089
Plasmodium falciparum plasmepsin II 0.0047 0.008 0.0309
Schistosoma mansoni neuropeptide F-like receptor 0.0308 0.1043 0.105
Loa Loa (eye worm) hypothetical protein 0.0068 0.0157 0.0339
Echinococcus multilocularis neuropeptide receptor 0.0308 0.1043 0.1177
Loa Loa (eye worm) hypothetical protein 0.0308 0.1043 0.2378
Onchocerca volvulus 0.0031 0.0019 0.0041
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0308 0.1043 0.105
Loa Loa (eye worm) ACC-1 protein 0.0148 0.0452 0.1019
Trypanosoma cruzi mitochondrial RNA binding complex 1 subunit, putative 0.0046 0.0074 0.0061
Trichomonas vaginalis leucine-rich repeat protein, BspA family 0.0246 0.0814 0.3057
Brugia malayi PAN domain containing protein 0.0201 0.065 0.1474
Echinococcus granulosus deoxyribonuclease ii 0.008 0.0199 0.0222
Echinococcus granulosus neuropeptide receptor 0.0308 0.1043 0.1177
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0089 0.0232 0.1354
Mycobacterium tuberculosis Ribonucleoside-diphosphate reductase (alpha chain) NrdE (ribonucleotide reductase small subunit) (R1F protein) 0.0343 0.1175 0.3761
Trypanosoma cruzi Zn-finger in Ran binding protein and others, putative 0.0046 0.0074 0.0061
Loa Loa (eye worm) hypothetical protein 0.0308 0.1043 0.2378
Loa Loa (eye worm) AUR protein kinase 0.0059 0.0123 0.0263
Loa Loa (eye worm) hypothetical protein 0.0068 0.0157 0.0339
Echinococcus granulosus tyrosine protein kinase Src64B 0.0044 0.0067 0.0072
Leishmania major beta tubulin 0.043 0.1497 1
Echinococcus granulosus glycine receptor subunit beta 0.0148 0.0452 0.0508
Mycobacterium ulcerans lipase LipD 0.0043 0.0065 0.0108
Brugia malayi conserved hypotetical protein 0.005 0.0091 0.0189
Echinococcus multilocularis anti dorsalizing morphogenetic protein 1a 0.0126 0.0371 0.0416
Echinococcus granulosus ephrin type A receptor 4 A 0.0198 0.0636 0.0717
Brugia malayi hypothetical protein 0.005 0.0091 0.0189
Mycobacterium tuberculosis Probable lipase LipE 0.0043 0.0065 0.0165
Toxoplasma gondii subtilisin SUB10 0.0054 0.0105 0.0105
Schistosoma mansoni transcription factor LCR-F1 0.0038 0.0045 0.0042
Schistosoma mansoni alpha-1 adrenergic receptor 0.0308 0.1043 0.105
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0044 0.0067 0.0072
Schistosoma mansoni RAR-like nuclear receptor 0.0107 0.03 0.03
Onchocerca volvulus 0.0201 0.065 0.276
Loa Loa (eye worm) hypothetical protein 0.005 0.0091 0.0188
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0113 0.0322 0.0361
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0046 0.0074 0.0149
Echinococcus multilocularis epidermal growth factor receptor 0.0735 0.2625 0.2969
Brugia malayi PAN domain containing protein 0.0201 0.065 0.1474
Echinococcus multilocularis membrane associated guanylate kinase ww and pdz 0.005 0.0091 0.0099
Onchocerca volvulus 0.0201 0.065 0.276
Echinococcus multilocularis glutamate receptor ionotropic kainate 0.0032 0.0022 0.0021
Schistosoma mansoni protein kinase 0.0127 0.0376 0.0376
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.0047 0.008 0.0202
Echinococcus multilocularis Tubulin beta 2C chain 0.043 0.1497 0.1691
Brugia malayi nuclear receptor NHR-88 0.0107 0.03 0.067
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0054 0.0105 0.0301
Echinococcus multilocularis rhodopsin orphan GPCR 0.0308 0.1043 0.1177
Brugia malayi PHD-finger family protein 0.0035 0.0035 0.0059
Schistosoma mansoni nuclear receptor 0.005 0.0091 0.0089
Echinococcus multilocularis Tubulin beta 2C chain 0.043 0.1497 0.1691
Brugia malayi Subtilase family protein 0.0054 0.0105 0.0221
Loa Loa (eye worm) hypothetical protein 0.005 0.0091 0.0188
Loa Loa (eye worm) hypothetical protein 0.0308 0.1043 0.2378
Loa Loa (eye worm) hypothetical protein 0.0201 0.065 0.1474
Brugia malayi ephrin receptor 1 precursor 0.0097 0.0262 0.0582
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0079 0.0198
Leishmania major beta tubulin 0.043 0.1497 1
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0107 0.03 0.067
Mycobacterium tuberculosis Probable proline rich membrane-anchored mycosin MycP5 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-5) 0.0054 0.0105 0.0295
Brugia malayi Kringle domain containing protein 0.0089 0.0232 0.0514
Echinococcus granulosus orexin receptor type 2 0.0308 0.1043 0.1177
Mycobacterium leprae conserved hypothetical protein 0.0863 0.31 1
Schistosoma mansoni glutamate receptor kainate 0.0032 0.0022 0.0019
Echinococcus granulosus nAChR subunit 0.008 0.02 0.0222
Schistosoma mansoni hypothetical protein 0.0308 0.1043 0.105
Trichomonas vaginalis hypothetical protein 0.0246 0.0814 0.3057
Entamoeba histolytica protein kinase domain containing protein 0.0059 0.0123 0.0276
Mycobacterium leprae Possible secreted protease 0.0054 0.0105 0.0238
Loa Loa (eye worm) hypothetical protein 0.0148 0.0452 0.1019
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0148 0.0452 0.1019
Chlamydia trachomatis SWIB complex protein 0.0129 0.0381 1
Echinococcus granulosus Nuclear hormone receptor HR96 0.005 0.0091 0.01
Loa Loa (eye worm) hypothetical protein 0.0148 0.0452 0.1019
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.03 0.1014 0.3839
Mycobacterium tuberculosis Probable lipase LipD 0.0043 0.0065 0.0165
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0068 0.0157 0.0174
Echinococcus granulosus biogenic amine 5HT receptor 0.0308 0.1043 0.1177
Loa Loa (eye worm) hypothetical protein 0.0148 0.0452 0.1019
Echinococcus granulosus matrix metallopeptidase 7 M10 family 0.0063 0.0137 0.0152
Onchocerca volvulus 0.0107 0.03 0.1254
Echinococcus granulosus segment polarity protein dishevelled 0.0098 0.0269 0.0301
Echinococcus granulosus tissue type plasminogen activator 0.0089 0.0232 0.026
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0059 0.0123 0.0607
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0148 0.0452 0.0508
Onchocerca volvulus 0.0135 0.0403 0.1697
Toxoplasma gondii hypothetical protein 0.0201 0.065 0.065
Schistosoma mansoni hypothetical protein 0.0135 0.0403 0.0404
Echinococcus multilocularis fmrfamide receptor 0.0308 0.1043 0.1177
Mycobacterium ulcerans proline rich membrane-anchored mycosin MycP5 0.0054 0.0105 0.0238
Schistosoma mansoni chromobox protein 0.0084 0.0216 0.0215
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0044 0.0067 0.0072
Schistosoma mansoni thyroid hormone receptor 0.0107 0.03 0.03
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0135 0.0403 0.0404
Toxoplasma gondii SWIB/MDM2 domain-containing protein 0.0129 0.0381 0.0381
Trichomonas vaginalis glucosylceramidase, putative 0.0176 0.0557 0.2058
Trichomonas vaginalis glucosylceramidase, putative 0.0255 0.0848 0.3191
Onchocerca volvulus 0.0054 0.0105 0.0413
Brugia malayi hypothetical protein 0.0286 0.0962 0.2191
Brugia malayi hypothetical protein 0.0308 0.1043 0.2378
Leishmania major ribonucleoside-diphosphate reductase large chain, putative 0.0083 0.021 0.1012
Brugia malayi Protein kinase domain containing protein 0.01 0.0274 0.061
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0115 0.0331 0.0371
Brugia malayi Deoxyribonuclease II family protein 0.008 0.0199 0.0436
Loa Loa (eye worm) hypothetical protein 0.0198 0.0637 0.1443
Mycobacterium ulcerans membrane-anchored serine protease (mycosin), MycP4 0.0054 0.0105 0.0238
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0148 0.0452 0.0508
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0107 0.03 0.03
Trichomonas vaginalis conserved hypothetical protein 0.0054 0.0105 0.0301
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0148 0.0452 0.1019
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0107 0.03 0.067
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0308 0.1043 0.1177
Schistosoma mansoni hypothetical protein 0.0129 0.0381 0.0382
Echinococcus multilocularis 0.007 0.0162 0.018
Loa Loa (eye worm) hypothetical protein 0.005 0.0091 0.0188
Onchocerca volvulus 0.0308 0.1043 0.4454
Onchocerca volvulus 0.0201 0.065 0.276
Brugia malayi sulfakinin receptor protein 0.0308 0.1043 0.2378
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0107 0.03 0.067
Plasmodium falciparum replication protein A1, large subunit 0.0049 0.0087 0.0358
Schistosoma mansoni dishevelled 0.0089 0.0232 0.0231
Leishmania major protein kinase, putative 0.0059 0.0123 0.0406
Brugia malayi hypothetical protein 0.0308 0.1043 0.2378
Brugia malayi hypothetical protein 0.0068 0.0157 0.034
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0135 0.0403 0.0453
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0043 0.0065 0.0063
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0148 0.0452 0.1019
Echinococcus granulosus ecdysone induced protein 78C 0.0107 0.03 0.0336
Brugia malayi Integrin alpha cytoplasmic region family protein 0.0231 0.0761 0.173
Loa Loa (eye worm) hypothetical protein 0.0107 0.03 0.067
Onchocerca volvulus 0.0046 0.0074 0.0279
Schistosoma mansoni tyrosine kinase 0.0321 0.1093 0.1101
Mycobacterium tuberculosis Conserved protein 0.0043 0.0065 0.0165
Echinococcus granulosus Zinc finger RanBP2 type 0.0046 0.0074 0.008
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0308 0.1043 0.105
Schistosoma mansoni nAChR subunit 0.0148 0.0452 0.0453
Loa Loa (eye worm) hypothetical protein 0.0201 0.065 0.1474
Schistosoma mansoni amine GPCR 0.0308 0.1043 0.105
Trypanosoma cruzi WLM domain containing protein, putative 0.0046 0.0074 0.0061
Echinococcus granulosus serotonin receptor 0.0308 0.1043 0.1177
Loa Loa (eye worm) nuclear receptor NHR-67 0.005 0.0091 0.0188
Schistosoma mansoni jumonji domain containing protein 0.0092 0.0243 0.0243
Loa Loa (eye worm) beta-tubulin 0.043 0.1497 0.3422
Brugia malayi tailless protein 0.005 0.0091 0.0189
Plasmodium falciparum SWIB/MDM2 domain-containing protein 0.0129 0.0381 0.237
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0107 0.03 0.067
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0148 0.0452 0.0453
Echinococcus granulosus neuropeptides capa receptor 0.0308 0.1043 0.1177
Brugia malayi G protein-coupled receptor 0.0308 0.1043 0.2378
Schistosoma mansoni biogenic amine (5HT) receptor 0.0308 0.1043 0.105
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0057 0.0113 0.0111
Trypanosoma brucei Zn-finger in Ran binding protein and others/FYVE zinc finger, putative 0.0046 0.0074 0.0026
Onchocerca volvulus 0.0032 0.0024 0.0062
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0107 0.03 0.067
Brugia malayi Glutamate receptor 2 precursor 0.0032 0.0022 0.0029
Echinococcus granulosus g protein coupled receptor 0.0308 0.1043 0.1177
Leishmania major beta tubulin 0.043 0.1497 1
Toxoplasma gondii replication factor-a protein 1 (rpa1) subfamily protein 0.0049 0.0087 0.0087
Echinococcus multilocularis g protein coupled receptor 0.0308 0.1043 0.1177
Brugia malayi hypothetical protein 0.0068 0.0157 0.034
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0107 0.03 0.067
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0046 0.0074 0.0149
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0135 0.0403 0.0453
Schistosoma mansoni matrix metallopeptidase-9 (M10 family) 0.004 0.0052 0.0049
Brugia malayi follicle stimulating hormone receptor 0.0308 0.1043 0.2378
Brugia malayi Bromodomain containing protein 0.0035 0.0035 0.0059
Echinococcus multilocularis thyroid hormone receptor alpha 0.0107 0.03 0.0336
Trypanosoma cruzi aurora B kinase, putative 0.0059 0.0123 0.0406
Schistosoma mansoni cercarial elastase (S01 family) 0.0135 0.0403 0.0404
Echinococcus granulosus biogenic amine 5HT receptor 0.0308 0.1043 0.1177
Loa Loa (eye worm) hypothetical protein 0.0068 0.0157 0.0339
Toxoplasma gondii 1,3(4)-beta-glucanase 0.0201 0.065 0.065
Loa Loa (eye worm) hypothetical protein 0.0179 0.0568 0.1286
Echinococcus multilocularis tyrosine protein kinase Srms 0.004 0.0053 0.0057
Loa Loa (eye worm) hypothetical protein 0.0068 0.0157 0.0339
Echinococcus granulosus neuropeptide s receptor 0.0308 0.1043 0.1177
Brugia malayi Cation transporter family protein 0.0476 0.1665 0.381
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0107 0.03 0.0336
Echinococcus granulosus nmda type glutamate receptor 0.0113 0.0322 0.0361
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0148 0.0452 0.1019
Schistosoma mansoni cercarial elastase (S01 family) 0.0135 0.0403 0.0404
Toxoplasma gondii subtilisin SUB7 0.0054 0.0105 0.0105
Loa Loa (eye worm) hypothetical protein 0.0046 0.0074 0.0149
Brugia malayi nuclear hormone receptor 0.005 0.0091 0.0189
Brugia malayi ecdysteroid receptor 0.0107 0.03 0.067
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0088 0.0231 0.0258
Brugia malayi hypothetical protein 0.0135 0.0403 0.0906
Leishmania major hypothetical protein, conserved 0.0046 0.0074 0.0061
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.152 0.5531 0.6258
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0148 0.0452 0.0508
Trypanosoma cruzi Replication factor A protein 1 0.0049 0.0087 0.0152
Plasmodium vivax SWIB/MDM2 domain-containing protein, putative 0.0129 0.0381 0.237
Onchocerca volvulus Matrilysin homolog 0.0063 0.0137 0.0551
Schistosoma mansoni hypothetical protein 0.0038 0.0045 0.0042
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0107 0.03 0.0336
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0148 0.0452 0.1019
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0308 0.1043 0.2378
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.0068 0.0157 0.0339
Echinococcus granulosus segment polarity protein dishevelled 0.0098 0.0269 0.0301
Trichomonas vaginalis tubulin beta chain, putative 0.043 0.1497 0.5716
Loa Loa (eye worm) hypothetical protein 0.0546 0.1925 0.4406
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0107 0.03 0.067
Echinococcus granulosus aurora kinase A 0.0059 0.0123 0.0136
Echinococcus granulosus tm gpcr rhodopsin 0.0308 0.1043 0.1177
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0308 0.1043 0.105
Schistosoma mansoni hypothetical protein 0.0078 0.0194 0.0193
Loa Loa (eye worm) hypothetical protein 0.0078 0.0194 0.0426
Leishmania major hypothetical protein, conserved 0.0046 0.0074 0.0061
Trichomonas vaginalis DNAse2-prov protein, putative 0.008 0.0199 0.0665
Schistosoma mansoni glutamate receptor NMDA 0.0267 0.0894 0.0899
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0308 0.1043 0.1177
Loa Loa (eye worm) hypothetical protein 0.0407 0.1413 0.3229
Schistosoma mansoni protein kinase 0.0059 0.0123 0.0121
Mycobacterium ulcerans hypothetical protein 0.0863 0.31 1
Leishmania major beta tubulin 0.043 0.1497 1
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0148 0.0452 0.1019
Echinococcus granulosus peptidase s8 s53 subtilisin kexin sedolisin 0.0054 0.0105 0.0115
Onchocerca volvulus 0.0037 0.0041 0.0137
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0107 0.03 0.0336
Onchocerca volvulus Glucosylceramidase homolog 0.0167 0.0523 0.2215
Echinococcus granulosus tubulin beta 4A class IVa 0.043 0.1497 0.1691
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0148 0.0452 0.1019
Plasmodium falciparum tubulin beta chain 0.043 0.1497 1
Echinococcus granulosus peregrin 0.0035 0.0035 0.0036
Mycobacterium tuberculosis Probable hydrolase 0.0043 0.0065 0.0165
Loa Loa (eye worm) hypothetical protein 0.0308 0.1043 0.2378
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.0267 0.0894 0.1008
Loa Loa (eye worm) hypothetical protein 0.0089 0.0232 0.0514
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0044 0.0067 0.0072
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0043 0.0065 0.0165
Onchocerca volvulus 0.0069 0.0161 0.0654
Echinococcus granulosus rhodopsin orphan GPCR 0.0308 0.1043 0.1177
Brugia malayi Melatonin receptor type 1A 0.0308 0.1043 0.2378
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0119 0.0343 0.1942
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0044 0.0067 0.0072
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0078 0.0194 0.0216
Loa Loa (eye worm) hypothetical protein 0.0047 0.008 0.0163
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0308 0.1043 0.105
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0107 0.03 0.0336
Loa Loa (eye worm) TYRA-2 protein 0.0308 0.1043 0.2378
Brugia malayi Tachykinin-like peptides receptor 99D 0.0546 0.1925 0.4406
Schistosoma mansoni serine-type protease inhibitor 0.2702 0.9908 1
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0476 0.1665 0.1678
Schistosoma mansoni cercarial elastase (S01 family) 0.0135 0.0403 0.0404
Schistosoma mansoni cercarial elastase (S01 family) 0.0135 0.0403 0.0404
Loa Loa (eye worm) hypothetical protein 0.0231 0.0761 0.173
Entamoeba histolytica tubulin family protein 0.043 0.1497 0.4763
Echinococcus multilocularis SWI:SNF matrix associated 0.0129 0.0381 0.0428
Loa Loa (eye worm) jmjC domain-containing protein 0.0073 0.0173 0.0378
Toxoplasma gondii PAN/Apple domain-containing protein 0.0201 0.065 0.065
Loa Loa (eye worm) hypothetical protein 0.0068 0.0157 0.0339
Loa Loa (eye worm) hypothetical protein 0.0032 0.0024 0.0033
Brugia malayi bZIP transcription factor family protein 0.0088 0.0231 0.0511
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0047 0.008 0.0077
Loa Loa (eye worm) hypothetical protein 0.0308 0.1043 0.2378
Echinococcus multilocularis integrin alpha ps 0.0137 0.0412 0.0463
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0179 0.0568 0.1286
Toxoplasma gondii DNA topoisomerase domain-containing protein 0.0129 0.0381 0.0381
Echinococcus multilocularis integrin alpha 3 0.0235 0.0773 0.0871
Echinococcus granulosus tyrosine protein kinase Fyn 0.0044 0.0067 0.0072
Brugia malayi AKH receptor 0.0308 0.1043 0.2378
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0107 0.03 0.067
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0054 0.0105 0.0301
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0294 0.0994 0.1121
Onchocerca volvulus 0.0043 0.0065 0.0241
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0107 0.03 0.067
Schistosoma mansoni tyrosine kinase 0.0315 0.1069 0.1076
Brugia malayi Kelch motif family protein 0.0058 0.0121 0.0257
Schistosoma mansoni hypothetical protein 0.0032 0.0022 0.0019
Toxoplasma gondii PHD-finger domain-containing protein 0.0035 0.0035 0.0035
Trichomonas vaginalis glucosylceramidase, putative 0.0255 0.0848 0.3191
Echinococcus granulosus Furin 1 0.03 0.1014 0.1145
Leishmania major beta tubulin 0.043 0.1497 1
Onchocerca volvulus 0.0201 0.065 0.276
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0038 0.0045 0.0047
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0308 0.1043 0.105
Trichomonas vaginalis replication factor A 1, rfa1, putative 0.0103 0.0285 0.1002
Entamoeba histolytica protein kinase, putative 0.01 0.0274 0.0769
Echinococcus multilocularis Ribosomal protein S1, RNA binding domain 0.0032 0.0022 0.0021
Onchocerca volvulus Matrix metalloproteinase homolog 0.0063 0.0137 0.0551
Echinococcus multilocularis epidermal growth factor receptor 0.0321 0.1093 0.1235
Echinococcus multilocularis Mastin 0.0135 0.0403 0.0453

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) = 0.0316 um PUBCHEM_BIOASSAY: qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53 Null Cells at the Permissive Temperature. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 1.4125 um PUBCHEM_BIOASSAY: qHTS Inhibitors of AmpC Beta-Lactamase (assay with detergent). (Class of assay: confirmatory) [Related pubchem assays: 1002 (Confirmation Concentration-Response Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent)), 585 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay without detergent) - a screen old NIH MLSMR collection), 584 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay with detergent) - a screen of the old NIH MLSMR collection), 1003 (Confirmation Cuvette-Based Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent))] ChEMBL. No reference
Potency (functional) = 3.5481 um PUBCHEM_BIOASSAY: qHTS Assay for Enhancers of SMN2 Splice Variant Expression. (Class of assay: confirmatory) ChEMBL. No reference
Potency (binding) = 3.5481 um PUBCHEM_BIOASSAY: qHTS Assay for Identification of Novel General Anesthetics. In this assay, a GABAergic mimetic model system, apoferritin and a profluorescent 1-aminoanthracene ligand (1-AMA), was used to construct a competitive binding assay for identification of novel general anesthetics (Class of assay: confirmatory) [Related pubchem assays: 2385 (Probe Development Summary for Identification of Novel General Anesthetics), 2323 (Validation apoferritin assay run on SigmaAldrich LOPAC1280 collection)] ChEMBL. No reference
Potency (functional) 11.2202 uM PUBCHEM_BIOASSAY: HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488962] ChEMBL. No reference
Potency (functional) 17.7828 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of JMJD2A-Tudor Domain. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504402] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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