Detailed information for compound 906689

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 437.485 | Formula: C25H27NO6
  • H donors: 1 H acceptors: 3 LogP: 2.22 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: COCCOC(=C1C(=NC2=C(C1c1coc3c(c1=O)cccc3)C(=O)CC(C2)(C)C)C)O
  • InChi: 1S/C25H27NO6/c1-14-20(24(29)31-10-9-30-4)21(22-17(26-14)11-25(2,3)12-18(22)27)16-13-32-19-8-6-5-7-15(19)23(16)28/h5-8,13,21,29H,9-12H2,1-4H3
  • InChiKey: YOVRYKDGKZQDQH-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0229 0.0488 0.5047
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0067 0.0099 0.0146
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0229 0.0488 0.1695
Loa Loa (eye worm) hypothetical protein 0.0165 0.0335 0.1162
Schistosoma mansoni thyroid hormone receptor 0.0041 0.0036 0.0052
Schistosoma mansoni peptidase Clp (S14 family) 0.0079 0.0129 0.0191
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0041 0.0036 0.0052
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0121 0.0229 0.034
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0229 0.0488 0.5047
Trichomonas vaginalis D-aminoacylase, putative 0.0109 0.02 0.2066
Plasmodium vivax serine-repeat antigen (SERA) 0.0071 0.0109 0.2231
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0079 0.0129 0.9786
Giardia lamblia Cathepsin B precursor 0.0428 0.0966 1
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0072 0.011 0.0777
Echinococcus multilocularis SAM and MBT domain containing protein 0.0102 0.0183 0.0182
Brugia malayi AMP-binding enzyme family protein 0.0028 0.0006 0.0017
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.0053 0.0078
Schistosoma mansoni patched 1 0.0218 0.0462 0.0688
Entamoeba histolytica cysteine protease, putative 0.0071 0.0109 0.0917
Echinococcus multilocularis peptidase Clp (S14 family) 0.0052 0.0063 0.0062
Plasmodium falciparum serine repeat antigen 6 0.0071 0.0109 0.2231
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0116 0.0216 0.0216
Plasmodium vivax ataxin-2 like protein, putative 0.0083 0.0138 0.2819
Plasmodium falciparum acyl-CoA synthetase 0.0072 0.011 0.2244
Brugia malayi Patched protein homolog 1 0.0031 0.0012 0.004
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0079 0.0129 0.0191
Brugia malayi intermediate filament protein 0.0056 0.0072 0.0246
Loa Loa (eye worm) ctsf protein 0.0229 0.0488 0.1695
Schistosoma mansoni BC026374 protein (S09 family) 0.0067 0.0099 0.0146
Giardia lamblia Cathepsin L precursor 0.0071 0.0109 0.1101
Brugia malayi Papain family cysteine protease containing protein 0.0071 0.0109 0.0378
Giardia lamblia Cathepsin B precursor 0.0071 0.0109 0.1101
Echinococcus granulosus cathepsin L cysteine protease 0.0135 0.0263 0.0391
Schistosoma mansoni hypothetical protein 0.0117 0.0219 0.0326
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0229 0.0488 0.5047
Brugia malayi cathepsin L-like precursor 0.0165 0.0335 0.1159
Plasmodium falciparum ataxin-2 like protein, putative 0.0083 0.0138 0.2819
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0068 0.0101 0.0591
Entamoeba histolytica hypothetical protein 0.0108 0.0198 0.1686
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0041 0.0036 0.0052
Echinococcus granulosus acetylcholinesterase 0.0067 0.0099 0.0146
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0041 0.0036 0.0052
Loa Loa (eye worm) hypothetical protein 0.0031 0.0012 0.0042
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0229 0.0488 0.5047
Mycobacterium ulcerans hypothetical protein 0.0097 0.0172 0.1235
Plasmodium vivax acetyl-CoA synthetase, putative 0.0028 0.0006 0.0101
Trichomonas vaginalis spcc417.12 protein, putative 0.0067 0.0099 0.1017
Loa Loa (eye worm) hypothetical protein 0.0026 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0041 0.0036 0.0124
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0041 0.0036 0.0052
Giardia lamblia Cathepsin B precursor 0.0428 0.0966 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0229 0.0488 0.5047
Brugia malayi 4-hydroxyphenylpyruvate dioxygenase family protein 0.0662 0.1529 0.5306
Trichomonas vaginalis conserved hypothetical protein 0.0071 0.0109 0.1126
Mycobacterium ulcerans beta-lactamase 0.0109 0.02 0.1448
Mycobacterium ulcerans acyl-CoA synthetase 0.0096 0.0168 0.121
Echinococcus granulosus mitogen activated protein kinase 3 0.005 0.0058 0.0086
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0041 0.0036 0.0052
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0041 0.0036 0.0122
Schistosoma mansoni inositol monophosphatase 0.0041 0.0037 0.0055
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.0093 0.0162 0.024
Loa Loa (eye worm) hypothetical protein 0.0041 0.0036 0.0124
Schistosoma mansoni thyroid hormone receptor 0.0041 0.0036 0.0052
Echinococcus granulosus microtubule associated protein 2 0.2821 0.6716 1
Trichomonas vaginalis chaperonin, putative 0.0027 0.0003 0.0027
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0165 0.0335 0.3457
Echinococcus multilocularis BC026374 protein (S09 family) 0.0067 0.0099 0.0098
Onchocerca volvulus 0.0162 0.0327 0.2133
Plasmodium falciparum serine repeat antigen 5 0.0071 0.0109 0.2231
Trichomonas vaginalis inositol monophosphatase, putative 0.0041 0.0037 0.0381
Toxoplasma gondii cathepsin CPC1 0.0071 0.0109 0.1126
Brugia malayi AMP-binding enzyme family protein 0.0028 0.0006 0.0017
Plasmodium falciparum serine repeat antigen 9 0.0071 0.0109 0.2231
Brugia malayi Cathepsin L-like precursor 0.0229 0.0488 0.1693
Loa Loa (eye worm) hypothetical protein 0.0109 0.02 0.0695
Loa Loa (eye worm) hypothetical protein 0.0956 0.2235 0.7759
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0071 0.0109 0.0378
Loa Loa (eye worm) hypothetical protein 0.0067 0.0099 0.0343
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0071 0.0109 0.0162
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0037 0.0027 0.0134
Loa Loa (eye worm) hypothetical protein 0.0071 0.0109 0.038
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0067 0.0099 0.058
Entamoeba histolytica hypothetical protein 0.0108 0.0198 0.1686
Onchocerca volvulus Protein patched homolog 0.0031 0.0012 0.0075
Brugia malayi Intermediate filament tail domain containing protein 0.0056 0.0072 0.0246
Schistosoma mansoni hypothetical protein 0.021 0.0444 0.066
Brugia malayi Cathepsin L-like precursor 0.0064 0.0092 0.0315
Entamoeba histolytica cysteine proteinase, putative 0.0135 0.0263 0.2244
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.005 0.0058 0.02
Plasmodium vivax unspecified product 0.0064 0.0092 0.1864
Trypanosoma cruzi major cysteine proteinase, putative 0.0071 0.0109 0.0378
Brugia malayi exodeoxyribonuclease III family protein 0.0081 0.0132 0.0454
Mycobacterium tuberculosis Conserved protein 0.0109 0.02 0.121
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0041 0.0036 0.0124
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0071 0.0109 0.0162
Mycobacterium ulcerans aldehyde dehydrogenase 0.0125 0.0238 0.1729
Loa Loa (eye worm) hypothetical protein 0.0031 0.0012 0.0042
Entamoeba histolytica hypothetical protein 0.0108 0.0198 0.1686
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0071 0.0109 0.0917
Schistosoma mansoni hypothetical protein 0.0117 0.0219 0.0326
Onchocerca volvulus 0.0028 0.0006 0.0032
Echinococcus granulosus cathepsin L 0.0071 0.0109 0.0162
Brugia malayi lactoylglutathione lyase 0.0097 0.0172 0.0593
Mycobacterium ulcerans esterase/lipase LipP 0.0109 0.02 0.1448
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0041 0.0036 0.0124
Schistosoma mansoni cathepsin C 0.0071 0.0109 0.0162
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0135 0.0263 0.2716
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0079 0.0129 0.0128
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0079 0.0129 0.0917
Onchocerca volvulus 0.0031 0.0012 0.0075
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0067 0.0099 0.0098
Echinococcus multilocularis polycomb protein SCMH1 0.0102 0.0183 0.0182
Plasmodium falciparum serine repeat antigen 4 0.0071 0.0109 0.2231
Echinococcus granulosus caspase 3 0.0071 0.011 0.0162
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0109 0.02 0.0693
Schistosoma mansoni hypothetical protein 0.0108 0.0198 0.0294
Schistosoma mansoni steroid hormone receptor ad4bp 0.0041 0.0036 0.0052
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0079 0.0129 0.9709
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0081 0.0132 0.1355
Plasmodium vivax patched family protein, putative 0.0031 0.0012 0.0234
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0096 0.0168 0.121
Brugia malayi Bromodomain containing protein 0.0084 0.014 0.0485
Mycobacterium leprae conserved hypothetical protein 0.0109 0.02 1
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0071 0.0109 0.2231
Onchocerca volvulus 0.0229 0.0488 0.319
Onchocerca volvulus 0.0102 0.0183 0.119
Plasmodium falciparum T-complex protein 1 subunit beta 0.0027 0.0003 0.0054
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0067 0.0099 0.0147
Loa Loa (eye worm) hypothetical protein 0.0046 0.0048 0.0166
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0081 0.0132 0.1331
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0081 0.0132 0.0783
Brugia malayi Myosin head containing protein 0.0031 0.0012 0.004
Trypanosoma cruzi cysteine peptidase, putative 0.0135 0.0263 0.0911
Loa Loa (eye worm) carboxylesterase 0.0067 0.0099 0.0343
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0428 0.0966 1
Schistosoma mansoni RAR-like nuclear receptor 0.0041 0.0036 0.0052
Brugia malayi Latrophilin receptor protein 2 0.0117 0.0219 0.076
Trichomonas vaginalis chaperonin-60kD, ch60, putative 0.0027 0.0003 0.0027
Toxoplasma gondii glyoxalase I, putative 0.0097 0.0172 0.1769
Echinococcus multilocularis histone acetyltransferase MYST2 0.0116 0.0216 0.0216
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0071 0.0109 0.2231
Loa Loa (eye worm) hypothetical protein 0.0041 0.0036 0.0124
Brugia malayi hypothetical protein 0.0054 0.0067 0.0231
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0041 0.0037 0.0381
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0229 0.0488 0.5047
Brugia malayi AMP-binding enzyme family protein 0.0028 0.0006 0.0017
Plasmodium falciparum lipid/sterol:H+ symporter 0.0031 0.0012 0.0234
Onchocerca volvulus 0.0067 0.0099 0.0642
Toxoplasma gondii patched family protein 0.0031 0.0012 0.0118
Loa Loa (eye worm) hypothetical protein 0.0056 0.0072 0.0248
Schistosoma mansoni acetyl-CoA synthetase 0.0028 0.0006 0.0007
Loa Loa (eye worm) hypothetical protein 0.0031 0.0012 0.0042
Trypanosoma cruzi cysteine protease, putative 0.0135 0.0263 0.0911
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0081 0.0132 0.0131
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0098 0.0172 0.0172
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0028 0.0006 0.0051
Brugia malayi AMP-binding enzyme family protein 0.0096 0.0168 0.0582
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0041 0.0036 0.0122
Loa Loa (eye worm) RNA binding protein 0.0139 0.0273 0.0946
Onchocerca volvulus 0.0052 0.0062 0.0404
Schistosoma mansoni gliotactin 0.0067 0.0099 0.0146
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0121 0.0229 0.0793
Trypanosoma cruzi hypothetical protein, conserved 0.0109 0.02 0.0693
Onchocerca volvulus 0.0067 0.0099 0.0642
Trypanosoma brucei protein kinase, putative 0.005 0.0058 0.0597
Schistosoma mansoni aldehyde dehydrogenase 0.0125 0.0238 0.0353
Echinococcus multilocularis musashi 0.0056 0.0072 0.0071
Echinococcus multilocularis mitogen activated protein kinase 0.005 0.0058 0.0058
Loa Loa (eye worm) hypothetical protein 0.0031 0.0012 0.0042
Giardia lamblia Cathepsin L precursor 0.0071 0.0109 0.1101
Echinococcus multilocularis Niemann Pick C1 protein 0.0509 0.116 0.116
Schistosoma mansoni hypothetical protein 0.0093 0.0162 0.024
Echinococcus multilocularis ecdysone induced protein 78C 0.0041 0.0036 0.0035
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0071 0.0109 0.2231
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0071 0.0109 0.2231
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0071 0.0109 0.2231
Echinococcus multilocularis importin subunit beta 1 0.0031 0.0012 0.0011
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0109 0.02 0.121
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0071 0.0109 0.1126
Entamoeba histolytica acyl-coA synthetase, putative 0.0096 0.0168 0.1426
Loa Loa (eye worm) hypothetical protein 0.0031 0.0012 0.0042
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0041 0.0037 0.0381
Echinococcus multilocularis carboxylesterase 5A 0.0067 0.0099 0.0098
Entamoeba histolytica cysteine proteinase, putative 0.0229 0.0488 0.4191
Trichomonas vaginalis esterase, putative 0.0109 0.02 0.2066
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0071 0.0109 0.0162
Entamoeba histolytica hypothetical protein 0.0108 0.0198 0.1686
Leishmania major 4-coumarate:coa ligase-like protein 0.0096 0.0168 0.1735
Loa Loa (eye worm) hypothetical protein 0.0031 0.0012 0.0042
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0071 0.0109 0.1126
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0135 0.0263 0.0391
Brugia malayi Steroid receptor seven-up type 2 0.0041 0.0036 0.0122
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0028 0.0006 0.0095
Schistosoma mansoni transcription factor LCR-F1 0.0108 0.0198 0.0294
Brugia malayi Nuclear hormone receptor-like 1 0.0041 0.0036 0.0122
Trypanosoma brucei hypothetical protein, conserved 0.0109 0.02 0.2066
Echinococcus multilocularis geminin 0.0703 0.1627 0.1627
Loa Loa (eye worm) hypothetical protein 0.0071 0.0109 0.038
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.004 0.0035 0.0051
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.005 0.0058 0.0597
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0071 0.0109 0.1101
Toxoplasma gondii cathepsin B 0.0428 0.0966 1
Plasmodium vivax vivapain-2 0.0229 0.0488 1
Loa Loa (eye worm) hypothetical protein 0.0031 0.0012 0.0042
Brugia malayi RNA, U transporter 1 0.0087 0.0148 0.051
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1225 0.2881 0.4289
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0229 0.0488 0.5047
Brugia malayi Papain family cysteine protease containing protein 0.0135 0.0263 0.0911
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0121 0.0229 0.034
Leishmania major cathepsin L-like protease 0.0229 0.0488 0.5047
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0041 0.0036 0.0122
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0067 0.0099 0.058
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0071 0.0109 0.1126
Loa Loa (eye worm) hypothetical protein 0.0253 0.0546 0.1896
Loa Loa (eye worm) hypothetical protein 0.0031 0.0012 0.0042
Loa Loa (eye worm) hypothetical protein 0.0096 0.0168 0.0584
Loa Loa (eye worm) hypothetical protein 0.0071 0.0109 0.038
Entamoeba histolytica cysteine protease, putative 0.0071 0.0109 0.0917
Loa Loa (eye worm) hypothetical protein 0.0102 0.0183 0.0634
Brugia malayi mbt repeat family protein 0.0102 0.0183 0.0632
Plasmodium vivax hypothetical protein, conserved 0.0109 0.02 0.4094
Schistosoma mansoni importin beta-1 0.0031 0.0012 0.0016
Brugia malayi Papain family cysteine protease containing protein 0.0229 0.0488 0.1693
Schistosoma mansoni 4-hydroxyphenylpyruvate dioxygenase 0.0097 0.0172 0.0254
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0071 0.0109 0.1126
Plasmodium vivax glyoxalase I, putative 0.0097 0.0172 0.3505
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0052 0.0063 0.0357
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0028 0.0006 0.0017
Entamoeba histolytica acyl-CoA synthetase, putative 0.0096 0.0168 0.1426
Entamoeba histolytica Ulp1 protease family, C-terminal catalytic domain containing protein 0.0145 0.0287 0.2451
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0125 0.0238 0.0353
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0058 0.0597
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0079 0.0129 1
Onchocerca volvulus 0.0096 0.0168 0.1097
Mycobacterium tuberculosis Cadmium inducible protein CadI 0.0097 0.0172 0.1032
Loa Loa (eye worm) hypothetical protein 0.0031 0.0012 0.0042
Giardia lamblia Cysteine protease 0.0071 0.0109 0.1101
Brugia malayi Cathepsin L-like cysteine proteinase 0.0165 0.0335 0.1159
Brugia malayi CHE-14 protein 0.0218 0.0462 0.1603
Toxoplasma gondii HEAT repeat-containing protein 0.0031 0.0012 0.0114
Brugia malayi Papain family cysteine protease containing protein 0.0071 0.0109 0.0378
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0028 0.0006 0.002
Schistosoma mansoni hypothetical protein 0.021 0.0444 0.066
Onchocerca volvulus Cathepsin F homolog 0.0229 0.0488 0.319
Trypanosoma cruzi hypothetical protein, conserved 0.0109 0.02 0.0693
Entamoeba histolytica cysteine protease, putative 0.0135 0.0263 0.2244
Brugia malayi Cathepsin L-like precursor 0.0229 0.0488 0.1693
Treponema pallidum exodeoxyribonuclease (exoA) 0.0081 0.0132 1
Echinococcus granulosus mitogen activated protein kinase 0.005 0.0058 0.0086
Echinococcus granulosus intermediate filament protein 0.0056 0.0072 0.0106
Leishmania major cathepsin L-like protease 0.0229 0.0488 0.5047
Onchocerca volvulus 0.0109 0.02 0.1306
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0081 0.0132 0.0195
Schistosoma mansoni inositol monophosphatase 0.0041 0.0037 0.0055
Loa Loa (eye worm) hypothetical protein 0.0055 0.0069 0.024
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0081 0.0132 0.0937
Echinococcus granulosus Niemann Pick C1 protein 0.0727 0.1685 0.2508
Brugia malayi Carboxylesterase family protein 0.0067 0.0099 0.0341
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0067 0.0099 0.0146
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0229 0.0488 0.5047
Plasmodium falciparum serine repeat antigen 3 0.0071 0.0109 0.2231
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0067 0.0099 0.1017
Leishmania major cathepsin L-like protease 0.0229 0.0488 0.5047
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0071 0.0109 0.2231
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0027 0.0004 0.0063
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0071 0.0109 0.0162
Loa Loa (eye worm) hypothetical protein 0.0064 0.0092 0.0318
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0041 0.0036 0.0035
Loa Loa (eye worm) hypothetical protein 0.0079 0.0129 0.0447
Mycobacterium leprae Probable lipase LipE 0.0109 0.02 1
Onchocerca volvulus Putative protein 0.0662 0.1529 1
Brugia malayi Patched family protein 0.0031 0.0012 0.004
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0041 0.0036 0.0122
Brugia malayi Patched family protein 0.0031 0.0012 0.004
Echinococcus granulosus cathepsin L 0.0135 0.0263 0.0391
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0041 0.0037 0.0128
Echinococcus granulosus ecdysone induced protein 78C 0.0041 0.0036 0.0052
Loa Loa (eye worm) hypothetical protein 0.0031 0.0012 0.0042
Giardia lamblia Cysteine protease 0.0071 0.0109 0.1101
Onchocerca volvulus 0.0109 0.02 0.1306
Schistosoma mansoni microtubule-associated protein tau 0.2821 0.6716 1
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0071 0.0109 0.0917
Loa Loa (eye worm) hypothetical protein 0.0116 0.0216 0.0751
Brugia malayi Patched family protein 0.0031 0.0012 0.004
Loa Loa (eye worm) patched family protein 0.0031 0.0012 0.0042
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0135 0.0263 0.0391
Entamoeba histolytica hypothetical protein 0.0071 0.0109 0.0917
Echinococcus multilocularis microtubule associated protein 2 0.2821 0.6716 0.6715
Loa Loa (eye worm) hypothetical protein 0.0031 0.0012 0.0042
Schistosoma mansoni hypothetical protein 0.021 0.0444 0.066
Onchocerca volvulus 0.0067 0.0099 0.0642
Mycobacterium ulcerans acyl-CoA synthetase 0.0096 0.0168 0.121
Trypanosoma cruzi cysteine peptidase, putative 0.0064 0.0092 0.0315
Onchocerca volvulus 0.0031 0.0012 0.0075
Entamoeba histolytica cysteine protease, putative 0.0135 0.0263 0.2244
Echinococcus granulosus BC026374 protein S09 family 0.0067 0.0099 0.0146
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0071 0.0109 0.038
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0135 0.0263 0.0911
Brugia malayi protein C24B5.3 0.0031 0.0012 0.004
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0229 0.0488 0.5047
Loa Loa (eye worm) hypothetical protein 0.0067 0.0099 0.0343
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0079 0.0129 0.2629
Mycobacterium ulcerans hypothetical protein 0.0097 0.0172 0.1235
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0229 0.0488 0.5047
Loa Loa (eye worm) hypothetical protein 0.0052 0.0062 0.0216
Mycobacterium ulcerans aldehyde dehydrogenase 0.0125 0.0238 0.1729
Mycobacterium tuberculosis Probable lipase LipE 0.0109 0.02 0.121
Onchocerca volvulus 0.0031 0.0012 0.0075
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0229 0.0488 0.5047
Trichomonas vaginalis conserved hypothetical protein 0.0218 0.0462 0.4781
Loa Loa (eye worm) hypothetical protein 0.0031 0.0012 0.0042
Echinococcus multilocularis FTZ F1 alpha 0.0121 0.0229 0.0228
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0071 0.0109 0.1126
Onchocerca volvulus 0.0028 0.0006 0.0032
Entamoeba histolytica cysteine proteinase, putative 0.0135 0.0263 0.2244
Brugia malayi Carboxylesterase family protein 0.0067 0.0099 0.0341
Entamoeba histolytica cysteine protease, putative 0.0135 0.0263 0.2244
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0067 0.0099 0.0146
Entamoeba histolytica cysteine proteinase 2 0.0135 0.0263 0.2244
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0096 0.0168 0.1012
Schistosoma mansoni cathepsin F (C01 family) 0.0229 0.0488 0.0726
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0027 0.0002 0.0003
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0229 0.0488 0.5047
Brugia malayi T-complex protein 1, beta subunit 0.0027 0.0003 0.0009
Loa Loa (eye worm) hypothetical protein 0.0064 0.0092 0.0318
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0125 0.0238 0.0237
Leishmania major acetyl-CoA synthetase, putative 0.0028 0.0006 0.0051
Schistosoma mansoni caspase-3 (C14 family) 0.0098 0.0172 0.0256
Loa Loa (eye worm) hypothetical protein 0.0064 0.0092 0.0318
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0229 0.0488 0.5047
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.0093 0.0162 0.0161
Giardia lamblia Cathepsin L precursor 0.0071 0.0109 0.1101
Loa Loa (eye worm) hypothetical protein 0.0031 0.0012 0.0042
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0041 0.0036 0.0052
Loa Loa (eye worm) T-complex protein 1 0.0027 0.0003 0.0012
Entamoeba histolytica cysteine protease, putative 0.0071 0.0109 0.0917
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0079 0.0129 0.0917
Brugia malayi cathepsin B-like cysteine proteinase 0.1225 0.2881 1
Loa Loa (eye worm) hypothetical protein 0.0509 0.116 0.4027
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0041 0.0036 0.0122
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0041 0.0036 0.0122
Echinococcus multilocularis cathepsin L cysteine protease 0.0229 0.0488 0.0488
Mycobacterium ulcerans glyoxalase GloA 0.0097 0.0172 0.1235
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0071 0.0109 0.1126
Schistosoma mansoni ap endonuclease 0.0081 0.0132 0.0195
Brugia malayi hypothetical protein 0.0031 0.0012 0.004
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0108 0.0198 0.0198
Echinococcus multilocularis beta LACTamase domain containing family member 0.0109 0.02 0.02
Trypanosoma cruzi major cysteine proteinase, putative 0.0071 0.0109 0.0378
Trypanosoma cruzi cysteine peptidase, putative 0.0229 0.0488 0.1693
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0041 0.0037 0.0381
Brugia malayi cathepsin L precursor 0.0071 0.0109 0.0378
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0121 0.0229 0.0228
Entamoeba histolytica cysteine protease, putative 0.0135 0.0263 0.2244
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0102 0.0183 0.0271
Brugia malayi Papain family cysteine protease containing protein 0.0071 0.0109 0.0378
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0028 0.0006 0.0017
Loa Loa (eye worm) latrophilin receptor protein 2 0.0117 0.0219 0.0762
Loa Loa (eye worm) hypothetical protein 0.0028 0.0006 0.0019
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0041 0.0036 0.0035
Schistosoma mansoni lamin 0.0056 0.0072 0.0106
Loa Loa (eye worm) patched family protein 0.0031 0.0012 0.0042
Loa Loa (eye worm) hypothetical protein 0.0165 0.0335 0.1162
Toxoplasma gondii aldehyde dehydrogenase 0.0125 0.0238 0.2457
Echinococcus granulosus expressed conserved protein 0.0478 0.1086 0.1616
Echinococcus granulosus peptidase Clp S14 family 0.0052 0.0063 0.0093
Onchocerca volvulus 0.0229 0.0488 0.319
Giardia lamblia Hypothetical protein 0.0071 0.0109 0.1101
Brugia malayi hypothetical protein 0.0067 0.0099 0.0341
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0428 0.0966 1
Echinococcus multilocularis cathepsin L cysteine protease 0.0229 0.0488 0.0488
Schistosoma mansoni hypothetical protein 0.0253 0.0546 0.0812
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0229 0.0488 0.5047
Plasmodium vivax importin-beta 2, putative 0.0031 0.0012 0.0226
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0028 0.0006 0.0005
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0064 0.0092 0.0315
Echinococcus multilocularis lamin 0.0056 0.0072 0.0071
Plasmodium falciparum ataxin-2 like protein, putative 0.0083 0.0138 0.2819
Mycobacterium tuberculosis Conserved protein TB27.3 0.0097 0.0172 0.1032
Echinococcus granulosus FTZ F1 alpha 0.042 0.0946 0.1408
Toxoplasma gondii glyoxalase family protein 0.0097 0.0172 0.1769
Entamoeba histolytica cysteine protease, putative 0.0135 0.0263 0.2244
Onchocerca volvulus 0.0056 0.0072 0.0464
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0041 0.0037 0.0381
Leishmania major T-complex protein 1, beta subunit, putative 0.0027 0.0003 0.0027
Giardia lamblia Cathepsin L precursor 0.0071 0.0109 0.1101
Mycobacterium ulcerans aldehyde dehydrogenase 0.0125 0.0238 0.1729
Entamoeba histolytica cysteine protease, putative 0.0135 0.0263 0.2244
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0098 0.0172 0.0256
Loa Loa (eye worm) hypothetical protein 0.0072 0.011 0.0382
Brugia malayi latrophilin 2 splice variant baaae 0.0253 0.0546 0.1894
Echinococcus granulosus polycomb protein SCMH1 0.0102 0.0183 0.0271
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0116 0.0216 0.0749
Echinococcus granulosus cathepsin b 0.1225 0.2881 0.4289
Brugia malayi Cathepsin L-like precursor 0.0229 0.0488 0.1693
Trichomonas vaginalis conserved hypothetical protein 0.0097 0.0172 0.1769
Mycobacterium tuberculosis Conserved protein 0.0109 0.02 0.121
Giardia lamblia Cathepsin L precursor 0.0071 0.0109 0.1101
Loa Loa (eye worm) acetylcholinesterase 1 0.0067 0.0099 0.0343
Plasmodium falciparum serine repeat antigen 7 0.0071 0.0109 0.2231
Giardia lamblia Hypothetical protein 0.0071 0.0109 0.1101
Echinococcus multilocularis caspase 3 0.0071 0.011 0.0109
Trichomonas vaginalis D-aminoacylase, putative 0.0109 0.02 0.2066
Loa Loa (eye worm) apoptosis regulator protein 0.0093 0.0162 0.0561
Echinococcus multilocularis acetylcholinesterase 0.0067 0.0099 0.0098
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0229 0.0488 0.5047
Schistosoma mansoni hypothetical protein 0.0635 0.1464 0.2179
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.005 0.0058 0.0202
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0071 0.0109 0.038
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0096 0.0168 0.8374
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0135 0.0263 0.0391
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.1225 0.2881 1
Entamoeba histolytica cysteine protease, putative 0.0229 0.0488 0.4191
Loa Loa (eye worm) hypothetical protein 0.0041 0.0036 0.0124
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0229 0.0488 0.1695
Loa Loa (eye worm) hypothetical protein 0.0267 0.058 0.2015
Plasmodium falciparum glyoxalase I 0.0097 0.0172 0.3505
Onchocerca volvulus Protein ultraspiracle homolog 0.0041 0.0036 0.0229
Echinococcus multilocularis neuroligin 0.0067 0.0099 0.0098
Loa Loa (eye worm) hypothetical protein 0.0031 0.0012 0.0042
Schistosoma mansoni cathepsin S (C01 family) 0.0071 0.0109 0.0162
Leishmania major cathepsin L-like protease 0.0229 0.0488 0.5047
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0041 0.0036 0.0052
Leishmania major hypothetical protein, conserved 0.0109 0.02 0.2066
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0067 0.0099 0.0098
Loa Loa (eye worm) hypothetical protein 0.0109 0.02 0.0695
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0165 0.0335 0.1159
Entamoeba histolytica cysteine protease, putative 0.0135 0.0263 0.2244
Schistosoma mansoni lipoxygenase 0.0054 0.0068 0.0101
Trichomonas vaginalis penicillin-binding protein, putative 0.0109 0.02 0.2066
Schistosoma mansoni cathepsin F (C01 family) 0.0165 0.0335 0.0497
Echinococcus granulosus Protein patched homolog 1 0.0218 0.0462 0.0688
Giardia lamblia Cathepsin B precursor 0.0071 0.0109 0.1101
Echinococcus granulosus beta LACTamase domain containing family member 0.0109 0.02 0.0297
Echinococcus granulosus cysteine protease 0.0135 0.0263 0.0391
Toxoplasma gondii preprocathepsin c precursor, putative 0.0071 0.0109 0.1126
Loa Loa (eye worm) patched family protein 0.0031 0.0012 0.0042
Onchocerca volvulus 0.0229 0.0488 0.319
Mycobacterium ulcerans lipase LipD 0.0109 0.02 0.1448
Toxoplasma gondii ABC1 family protein 0.0109 0.02 0.2066
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0028 0.0006 0.0017
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.005 0.0058 0.0597
Brugia malayi Patched family protein 0.0031 0.0012 0.004
Echinococcus multilocularis para nitrobenzyl esterase 0.0067 0.0099 0.0098
Plasmodium vivax unspecified product 0.0071 0.0109 0.2231
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1225 0.2881 0.4289
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0071 0.0109 0.2231
Brugia malayi AMP-binding enzyme family protein 0.0096 0.0168 0.0582
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.0053 0.0078
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0079 0.0129 0.1327
Loa Loa (eye worm) hypothetical protein 0.0071 0.0109 0.038
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0229 0.0488 0.5047
Echinococcus granulosus histone acetyltransferase MYST2 0.0116 0.0216 0.0321
Trypanosoma cruzi cysteine proteinase, putative 0.0135 0.0263 0.0911
Schistosoma mansoni acetylcholinesterase 0.0067 0.0099 0.0146
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0028 0.0006 0.0051
Brugia malayi Probable ClpP-like protease 0.0079 0.0129 0.0445
Loa Loa (eye worm) intermediate filament protein 0.0056 0.0072 0.0248
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0229 0.0488 0.5047
Echinococcus multilocularis inositol monophosphatase 1 0.0041 0.0037 0.0037
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0041 0.0036 0.0035
Brugia malayi Patched family protein 0.0031 0.0012 0.004
Schistosoma mansoni hypothetical protein 0.008 0.0131 0.0195
Mycobacterium tuberculosis Conserved protein 0.0109 0.02 0.121
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0135 0.0263 0.2716
Loa Loa (eye worm) hypothetical protein 0.0031 0.0012 0.0042
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0071 0.0109 0.1126
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0071 0.0109 0.0162
Loa Loa (eye worm) hypothetical protein 0.0121 0.0229 0.0795
Echinococcus multilocularis mitogen activated protein kinase 3 0.005 0.0058 0.0058
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0509 0.116 1
Schistosoma mansoni hypothetical protein 0.0703 0.1627 0.2423
Brugia malayi fibroinase precursor 0.0071 0.0109 0.0378
Loa Loa (eye worm) hypothetical protein 0.0031 0.0012 0.0042
Brugia malayi hypothetical protein 0.0031 0.0012 0.004
Trichomonas vaginalis ap endonuclease, putative 0.0081 0.0132 0.1355
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0117 0.0219 0.076
Loa Loa (eye worm) hypothetical protein 0.0218 0.0462 0.1605
Brugia malayi Patched related family protein 12 0.0031 0.0012 0.004
Brugia malayi ecdysteroid receptor 0.0041 0.0036 0.0122
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.0053 0.0078
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0195 0.0407 0.1409
Schistosoma mansoni aldehyde dehydrogenase 0.0125 0.0238 0.0353
Schistosoma mansoni caspase-7 (C14 family) 0.0098 0.0172 0.0256
Schistosoma mansoni tar DNA-binding protein 0.0139 0.0273 0.0405
Schistosoma mansoni hypothetical protein 0.0093 0.0162 0.024
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0071 0.0109 0.2231
Schistosoma mansoni myelin transcription factor 1 myt1 0.0116 0.0216 0.0321
Loa Loa (eye worm) fibroinase 0.0229 0.0488 0.1695
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0117 0.0219 0.0326
Loa Loa (eye worm) hypothetical protein 0.0031 0.0012 0.0042
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0028 0.0006 0.0017
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.004 0.0035 0.0034
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0027 0.0002 0.0002
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0037 0.0027 0.1188
Entamoeba histolytica cysteine protease, putative 0.0135 0.0263 0.2244
Brugia malayi Patched family protein 0.0031 0.0012 0.004
Onchocerca volvulus 0.0195 0.0407 0.2656
Plasmodium falciparum glyoxalase I 0.0097 0.0172 0.3505
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0229 0.0488 0.5047
Loa Loa (eye worm) hypothetical protein 0.0109 0.02 0.0695
Schistosoma mansoni coup transcription factor 0.0041 0.0036 0.0052
Onchocerca volvulus 0.0067 0.0099 0.0642
Onchocerca volvulus 0.0109 0.02 0.1306
Plasmodium vivax acyl-CoA synthetase, putative 0.0072 0.011 0.2244
Loa Loa (eye worm) hypothetical protein 0.0067 0.0099 0.0343
Trypanosoma cruzi cysteine peptidase, putative 0.0229 0.0488 0.1693
Loa Loa (eye worm) hypothetical protein 0.0165 0.0335 0.1162
Schistosoma mansoni hypothetical protein 0.0327 0.0725 0.1079
Trichomonas vaginalis ap endonuclease, putative 0.0081 0.0132 0.1355
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0121 0.0229 0.0793
Giardia lamblia Cathepsin B precursor 0.0071 0.0109 0.1101
Brugia malayi Niemann-Pick C1 protein precursor 0.0509 0.116 0.4026
Loa Loa (eye worm) hypothetical protein 0.0109 0.02 0.0695
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0081 0.0132 0.1355
Loa Loa (eye worm) hypothetical protein 0.0043 0.0042 0.0144
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.0093 0.0162 0.024
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0041 0.0036 0.0122
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0229 0.0488 0.5047
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0071 0.0109 0.0162
Echinococcus granulosus sterol regulatory element binding protein 0.0218 0.0462 0.0688
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0041 0.0037 0.0295
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.0093 0.0162 0.0161
Loa Loa (eye worm) hypothetical protein 0.0031 0.0012 0.0042
Onchocerca volvulus Cathepsin L homolog 0.0229 0.0488 0.319
Echinococcus multilocularis expressed conserved protein 0.0133 0.0256 0.0256
Brugia malayi nuclear receptor NHR-88 0.0041 0.0036 0.0122
Loa Loa (eye worm) patched family protein 0.0031 0.0012 0.0042
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0071 0.0109 0.0162
Schistosoma mansoni hypothetical protein 0.0703 0.1627 0.2423
Schistosoma mansoni tar DNA-binding protein 0.0139 0.0273 0.0405
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0067 0.0099 0.0146
Brugia malayi hypothetical protein 0.0083 0.0138 0.0477
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0028 0.0006 0.0019
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0229 0.0488 0.5047
Entamoeba histolytica cysteine proteinase, putative 0.0135 0.0263 0.2244
Trypanosoma brucei importin beta-1 subunit, putative 0.0031 0.0012 0.0114
Brugia malayi Inositol-1 0.0041 0.0037 0.0128
Brugia malayi hypothetical protein 0.0956 0.2235 0.7758
Echinococcus multilocularis Niemann Pick C1 protein 0.0727 0.1685 0.1684
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0109 0.02 0.0297
Trypanosoma brucei PAB1-binding protein , putative 0.0083 0.0138 0.1423
Schistosoma mansoni neuroligin 3 (S09 family) 0.0067 0.0099 0.0146
Echinococcus multilocularis expressed conserved protein 0.0478 0.1086 0.1085
Schistosoma mansoni hypothetical protein 0.0117 0.0219 0.0326
Echinococcus granulosus cathepsin l1 0.0229 0.0488 0.0726
Entamoeba histolytica cysteine proteinase, putative 0.0165 0.0335 0.2864
Echinococcus granulosus lamin dm0 0.0056 0.0072 0.0106
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0109 0.02 0.0297
Trypanosoma cruzi cruzipain precursor, putative 0.0064 0.0092 0.0315
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0041 0.0036 0.0229
Onchocerca volvulus 0.0041 0.0036 0.0229
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.1225 0.2881 0.4289
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0071 0.0109 0.1126
Brugia malayi cathepsin F-like cysteine proteinase 0.0071 0.0109 0.0378
Trypanosoma cruzi T-complex protein 1, beta subunit, putative 0.0027 0.0003 0.0009
Loa Loa (eye worm) hypothetical protein 0.0096 0.0168 0.0584
Echinococcus granulosus expressed conserved protein 0.0133 0.0256 0.0381
Leishmania major cathepsin L-like protease 0.0229 0.0488 0.5047
Echinococcus multilocularis caspase 0.0098 0.0172 0.0172
Giardia lamblia Cathepsin B precursor 0.0071 0.0109 0.1101
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0079 0.0129 0.6365
Brugia malayi Patched family protein 0.0031 0.0012 0.004
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0081 0.0132 0.1108
Plasmodium falciparum cysteine proteinase falcipain 1 0.0135 0.0263 0.538
Trypanosoma cruzi lactoylglutathione lyase-like protein, putative 0.0097 0.0172 0.0593
Brugia malayi hypothetical protein 0.0108 0.0198 0.0687
Loa Loa (eye worm) hypothetical protein 0.0072 0.011 0.0382
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0041 0.0036 0.0052
Loa Loa (eye worm) hypothetical protein 0.0067 0.0099 0.0343
Plasmodium falciparum cysteine proteinase falcipain 3 0.0229 0.0488 1
Entamoeba histolytica cysteine protease, putative 0.0135 0.0263 0.2244
Loa Loa (eye worm) hypothetical protein 0.0162 0.0327 0.1134
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0417 0.0941 0.094
Onchocerca volvulus Cathepsin L homolog 0.0071 0.0109 0.0711
Brugia malayi cathepsin F-like cysteine proteinase 0.0064 0.0092 0.0315
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0058 0.0597
Loa Loa (eye worm) hypothetical protein 0.0027 0.0002 0.0008
Leishmania major hypothetical protein, conserved 0.0083 0.0138 0.1423
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0068 0.0101 0.0591
Echinococcus granulosus inositol monophosphatase 1 0.0041 0.0037 0.0055
Mycobacterium ulcerans acyl-CoA synthetase 0.0096 0.0168 0.121
Mycobacterium ulcerans hypothetical protein 0.0109 0.02 0.1448
Loa Loa (eye worm) hypothetical protein 0.0031 0.0012 0.0042
Onchocerca volvulus 0.0031 0.0012 0.0075
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0041 0.0036 0.0035
Echinococcus multilocularis tumor protein p63 0.0354 0.0788 0.0787
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0064 0.0092 0.0318
Mycobacterium ulcerans carboxylesterase, LipT 0.0587 0.135 1
Schistosoma mansoni nuclear hormone receptor 0.0041 0.0036 0.0052
Onchocerca volvulus 0.0031 0.0012 0.0075
Onchocerca volvulus 0.0229 0.0488 0.319
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.005 0.0058 0.0597
Brugia malayi T-complex protein 1, beta subunit 0.0027 0.0003 0.0009
Onchocerca volvulus 0.0229 0.0488 0.319
Schistosoma mansoni apoptosis regulator bax 0.0093 0.0162 0.024
Plasmodium falciparum importin beta, putative 0.0031 0.0012 0.0226
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0096 0.0168 0.121
Loa Loa (eye worm) hypothetical protein 0.0026 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0031 0.0012 0.0042
Entamoeba histolytica cysteine protease, putative 0.0135 0.0263 0.2244
Loa Loa (eye worm) hypothetical protein 0.0067 0.0099 0.0343
Loa Loa (eye worm) hypothetical protein 0.0031 0.0012 0.0042
Brugia malayi Patched family protein 0.0031 0.0012 0.004
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0516 0.1179 0.1755
Mycobacterium ulcerans hypothetical protein 0.0097 0.0172 0.1235
Schistosoma mansoni intermediate filament proteins 0.0056 0.0072 0.0106
Loa Loa (eye worm) hypothetical protein 0.0031 0.0012 0.0041
Loa Loa (eye worm) 4-hydroxyphenylpyruvate dioxygenase 0.0662 0.1529 0.5307
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0229 0.0488 0.5047
Toxoplasma gondii exonuclease III APE 0.0081 0.0132 0.1355
Schistosoma mansoni tar DNA-binding protein 0.0139 0.0273 0.0405
Plasmodium vivax glyoxalase I, putative 0.0097 0.0172 0.3505
Echinococcus granulosus lamin 0.0056 0.0072 0.0106
Loa Loa (eye worm) hypothetical protein 0.0031 0.0012 0.0042
Loa Loa (eye worm) inositol-1 0.0041 0.0037 0.013
Loa Loa (eye worm) cysteine protease 0.0229 0.0488 0.1695
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0027 0.0004 0.0063
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0041 0.0036 0.0124
Brugia malayi Patched family protein 0.0031 0.0012 0.004
Toxoplasma gondii propionate-CoA ligase 0.0028 0.0006 0.0051
Loa Loa (eye worm) TAR-binding protein 0.0139 0.0273 0.0946
Onchocerca volvulus 0.0031 0.0012 0.0075
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0041 0.0036 0.0052
Loa Loa (eye worm) hypothetical protein 0.0041 0.0036 0.0124
Leishmania major cathepsin L-like protease 0.0229 0.0488 0.5047
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0117 0.0219 0.0219
Schistosoma mansoni ap endonuclease 0.0081 0.0132 0.0195
Schistosoma mansoni family C48 unassigned peptidase (C48 family) 0.0145 0.0287 0.0426
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0041 0.0036 0.0124
Mycobacterium tuberculosis Probable lipase LipD 0.0109 0.02 0.121
Brugia malayi cathepsin Z-like cysteine proteinase 0.0071 0.0109 0.0378
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0109 0.02 0.121
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0229 0.0488 0.5047
Loa Loa (eye worm) cathepsin B 0.0428 0.0966 0.3355
Brugia malayi Carboxylesterase family protein 0.0067 0.0099 0.0341
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0096 0.0168 0.8374
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0229 0.0488 0.5047
Loa Loa (eye worm) hypothetical protein 0.0096 0.0168 0.0584
Loa Loa (eye worm) carboxylesterase 0.0067 0.0099 0.0343
Echinococcus multilocularis sentrin specific protease 7 0.0145 0.0287 0.0286
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0109 0.02 0.1448
Leishmania major glyoxalase I,trypanothione-dependent glyoxalase I 0.0097 0.0172 0.1769
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0229 0.0488 0.5047
Brugia malayi photoreceptor-specific nuclear receptor 0.0041 0.0036 0.0122
Loa Loa (eye worm) hypothetical protein 0.0072 0.011 0.0382
Schistosoma mansoni retinoic acid receptor RXR 0.0041 0.0036 0.0052
Entamoeba histolytica cysteine protease, putative 0.0071 0.0109 0.0917
Brugia malayi Patched family protein 0.0031 0.0012 0.004
Brugia malayi Patched related family protein 4 0.0031 0.0012 0.004
Giardia lamblia Cathepsin L-like protease 0.0071 0.0109 0.1101
Brugia malayi protein C24B5.3 0.0031 0.0012 0.004
Echinococcus granulosus sentrin specific protease 7 0.0145 0.0287 0.0426
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0028 0.0006 0.0095
Mycobacterium tuberculosis Conserved protein 0.0097 0.0172 0.1032
Loa Loa (eye worm) hypothetical protein 0.0031 0.0012 0.0042
Trypanosoma cruzi cysteine proteinase, putative 0.0135 0.0263 0.0911
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0071 0.0109 0.1126
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.005 0.0058 0.0597
Giardia lamblia Cathepsin L precursor 0.0071 0.0109 0.1101
Brugia malayi beta-lactamase family protein 0.0109 0.02 0.0693
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0229 0.0488 0.5047
Loa Loa (eye worm) hypothetical protein 0.0097 0.0172 0.0595
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0048 0.0053 0.0078
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0071 0.0109 0.2231
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0109 0.02 0.121
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0028 0.0006 0.0019
Echinococcus granulosus para nitrobenzyl esterase 0.0067 0.0099 0.0146
Loa Loa (eye worm) hypothetical protein 0.0067 0.0099 0.0343
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1225 0.2881 0.4289
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0048 0.0053 0.0052
Loa Loa (eye worm) mbt repeat family protein 0.0102 0.0183 0.0634
Echinococcus granulosus neuroligin 0.0067 0.0099 0.0146
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0229 0.0488 0.5047
Schistosoma mansoni sex comb on midleg homolog 0.0102 0.0183 0.0271
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0125 0.0238 0.1445
Schistosoma mansoni hypothetical protein 0.0037 0.0028 0.004
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.0093 0.0162 0.024
Schistosoma mansoni sex comb on midleg homolog 0.0102 0.0183 0.0271
Mycobacterium leprae conserved hypothetical protein 0.0097 0.0172 0.8538
Mycobacterium ulcerans hypothetical protein 0.0097 0.0172 0.1235
Mycobacterium tuberculosis Probable esterase LipL 0.0109 0.02 0.121
Entamoeba histolytica cysteine protease, putative 0.0071 0.0109 0.0917
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0417 0.0941 0.14
Mycobacterium tuberculosis Conserved protein 0.0097 0.0172 0.1032
Echinococcus granulosus caspase 0.0098 0.0172 0.0256
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0697 0.1613 1
Schistosoma mansoni lamin 0.0056 0.0072 0.0106
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0058 0.0597
Brugia malayi cathepsin L-like cysteine proteinase 0.0071 0.0109 0.0378
Brugia malayi AMP-binding enzyme family protein 0.0096 0.0168 0.0582
Schistosoma mansoni tar DNA-binding protein 0.0139 0.0273 0.0405
Loa Loa (eye worm) hypothetical protein 0.0031 0.0012 0.0042
Trypanosoma cruzi cysteine peptidase, putative 0.0229 0.0488 0.1693
Onchocerca volvulus 0.0032 0.0015 0.0096
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0071 0.0109 0.0162
Mycobacterium tuberculosis Conserved hypothetical protein 0.0097 0.0172 0.1032
Brugia malayi Carboxylesterase family protein 0.0067 0.0099 0.0341
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0054 0.0068 0.0068
Brugia malayi Patched family protein 0.0031 0.0012 0.004
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0229 0.0488 0.5047
Loa Loa (eye worm) hypothetical protein 0.0031 0.0012 0.0042
Loa Loa (eye worm) hypothetical protein 0.0041 0.0036 0.0124
Echinococcus granulosus cathepsin l1 0.0165 0.0335 0.0497
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0079 0.0129 0.2629
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0048 0.0053 0.0078
Onchocerca volvulus 0.0028 0.0006 0.0032
Echinococcus multilocularis acetylcholinesterase 0.0067 0.0099 0.0098
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0028 0.0006 0.0051
Brugia malayi nuclear hormone receptor 0.0041 0.0036 0.0122
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0229 0.0488 1
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0027 0.0003 0.0004
Schistosoma mansoni hypothetical protein 0.0117 0.0219 0.0326
Schistosoma mansoni serine/threonine protein kinase 0.005 0.0058 0.0086
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0048 0.0053 0.0182
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0041 0.0036 0.0122
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0048 0.0053 0.0052
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0229 0.0488 0.5047
Echinococcus granulosus cathepsin l cysteine peptidase 0.0229 0.0488 0.0726
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.003 0.001 0.0033
Brugia malayi PHD-finger family protein 0.0028 0.0005 0.0016
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0108 0.0198 0.0294
Loa Loa (eye worm) hypothetical protein 0.1225 0.2881 1
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0058 0.0597
Schistosoma mansoni hypothetical protein 0.0195 0.0407 0.0604
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0028 0.0006 0.0017
Leishmania major 4-coumarate:coa ligase-like protein 0.0096 0.0168 0.1735
Loa Loa (eye worm) hypothetical protein 0.0093 0.0162 0.0561
Loa Loa (eye worm) hypothetical protein 0.0079 0.0129 0.0447
Mycobacterium ulcerans hypothetical protein 0.0097 0.0172 0.1235
Echinococcus multilocularis cathepsin L 0.0071 0.0109 0.0109
Plasmodium falciparum serine repeat antigen 1 0.0071 0.0109 0.2231
Brugia malayi hypothetical protein 0.0031 0.0012 0.004
Onchocerca volvulus 0.0229 0.0488 0.319
Brugia malayi hypothetical protein 0.0162 0.0327 0.1132
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0096 0.0168 0.1012
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0081 0.0132 0.2685
Loa Loa (eye worm) hypothetical protein 0.0031 0.0012 0.0042
Echinococcus multilocularis tar DNA binding protein 0.0139 0.0273 0.0272
Loa Loa (eye worm) hypothetical protein 0.0109 0.02 0.0695
Loa Loa (eye worm) hypothetical protein 0.0031 0.0012 0.0042
Mycobacterium ulcerans biphenyl-2,3-diol 1,2-dioxygenase 0.0097 0.0172 0.1235
Loa Loa (eye worm) patched family protein 0.0031 0.0012 0.0042
Trypanosoma cruzi cruzipain precursor, putative 0.0229 0.0488 0.1693
Brugia malayi Calcitonin receptor-like protein seb-1 0.037 0.0827 0.2871
Mycobacterium ulcerans hypothetical protein 0.0096 0.0168 0.121
Loa Loa (eye worm) hypothetical protein 0.0071 0.0109 0.038
Trichomonas vaginalis conserved hypothetical protein 0.0071 0.0109 0.1126
Loa Loa (eye worm) hypothetical protein 0.0031 0.0012 0.0042
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0068 0.0101 0.0591
Mycobacterium ulcerans glyoxalase GloA 0.0097 0.0172 0.1235
Giardia lamblia Cysteine protease 0.0071 0.0109 0.1101
Toxoplasma gondii hypothetical protein 0.0031 0.0012 0.0118
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0041 0.0036 0.0124
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0229 0.0488 0.5047
Onchocerca volvulus 0.0071 0.0109 0.0711
Echinococcus granulosus cathepsin L cysteine proteinase 0.0229 0.0488 0.0726
Entamoeba histolytica cysteine protease, putative 0.0071 0.0109 0.0917
Brugia malayi steroid hormone receptor 0.0041 0.0036 0.0122
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0041 0.0036 0.0124
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0081 0.0132 0.0454
Toxoplasma gondii patched family protein 0.0031 0.0012 0.0118
Loa Loa (eye worm) carboxylesterase 0.0067 0.0099 0.0343
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0165 0.0335 0.3457
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0037 0.0028 0.0027
Loa Loa (eye worm) hypothetical protein 0.0117 0.0219 0.0762
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0079 0.0129 1
Trypanosoma cruzi lactoylglutathione lyase-like protein, putative 0.0097 0.0172 0.0593
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0041 0.0037 0.0381
Echinococcus multilocularis protein patched 0.0218 0.0462 0.0462
Leishmania major cathepsin L-like protease 0.0229 0.0488 0.5047
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.005 0.0058 0.02
Loa Loa (eye worm) hypothetical protein 0.0229 0.0488 0.1695
Echinococcus granulosus GPCR family 2 0.0117 0.0219 0.0326
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0071 0.0109 0.1126
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0096 0.0168 0.121
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0041 0.0036 0.0122
Trypanosoma cruzi PAB1-binding protein , putative 0.0083 0.0138 0.0477
Loa Loa (eye worm) hypothetical protein 0.0072 0.011 0.0382
Loa Loa (eye worm) hypothetical protein 0.0031 0.0012 0.0042
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0041 0.0037 0.0128
Echinococcus granulosus chaperonin containing TCP1 subunit 2 beta 0.0027 0.0003 0.0004
Loa Loa (eye worm) hypothetical protein 0.0109 0.02 0.0695
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0079 0.0129 0.1327
Echinococcus multilocularis sterol regulatory element binding protein 0.0218 0.0462 0.0462
Trichomonas vaginalis antibiotic synthetase, putative 0.0028 0.0006 0.0051
Brugia malayi AMP-binding enzyme family protein 0.0028 0.0006 0.0017
Onchocerca volvulus 0.0056 0.0072 0.0464
Brugia malayi mbt repeat family protein 0.0102 0.0183 0.0632
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0041 0.0036 0.0052
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0081 0.0132 0.0454
Schistosoma mansoni bromodomain containing protein 0.0071 0.0109 0.0161
Brugia malayi Cathepsin L-like precursor 0.0165 0.0335 0.1159
Plasmodium vivax serine-repeat antigen (SERA) 0.0071 0.0109 0.2231
Brugia malayi hypothetical protein 0.0031 0.0012 0.004
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0071 0.0109 0.1126
Echinococcus multilocularis GPCR, family 2 0.0117 0.0219 0.0219
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0139 0.0273 0.0946
Trichomonas vaginalis conserved hypothetical protein 0.0097 0.0172 0.1769
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0428 0.0966 0.3354
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0229 0.0488 0.5047
Schistosoma mansoni cellular tumor antigen P53 0.0052 0.0062 0.0092
Brugia malayi Patched family protein 0.0031 0.0012 0.004
Echinococcus multilocularis protein dispatched 1 0.0249 0.0537 0.0536
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0081 0.0132 1
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0071 0.0109 0.1101
Loa Loa (eye worm) pigment dispersing factor receptor c 0.037 0.0827 0.2873
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0071 0.0109 0.0162
Schistosoma mansoni cathepsin s 0.0064 0.0092 0.0135
Loa Loa (eye worm) hypothetical protein 0.0031 0.0012 0.0042
Onchocerca volvulus Bile acid receptor homolog 0.0041 0.0036 0.0229
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0028 0.0006 0.0007
Leishmania major 4-coumarate:coa ligase-like protein 0.0096 0.0168 0.1735
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0116 0.0216 0.0321
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0041 0.0036 0.0124
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0071 0.0109 0.1126
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0229 0.0488 1
Trichomonas vaginalis antibiotic synthetase, putative 0.0028 0.0006 0.0051
Entamoeba histolytica cysteine protease, putative 0.0135 0.0263 0.2244
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0102 0.0183 0.119
Loa Loa (eye worm) steroid hormone receptor 0.0041 0.0036 0.0124
Plasmodium vivax vivapain-1 0.0135 0.0263 0.538
Echinococcus granulosus SAM and MBT domain containing protein 0.0102 0.0183 0.0271
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0229 0.0488 0.5047
Entamoeba histolytica cysteine proteinase 1, putative 0.0135 0.0263 0.2244
Echinococcus multilocularis cysteine protease 0.0229 0.0488 0.0488
Brugia malayi cytoplasmic intermediate filament protein 0.003 0.001 0.0031
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0071 0.0109 0.1126
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0027 0.0003 0.0004
Loa Loa (eye worm) hypothetical protein 0.0067 0.0099 0.0343
Brugia malayi Papain family cysteine protease containing protein 0.0135 0.0263 0.0911
Toxoplasma gondii hypothetical protein 0.0027 0.0004 0.0032
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0081 0.0132 0.0457
Brugia malayi Cathepsin L-like precursor 0.0165 0.0335 0.1159
Mycobacterium tuberculosis Carboxylesterase LipT 0.0587 0.135 0.8358
Onchocerca volvulus Protein patched homolog 0.0031 0.0012 0.0075
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0028 0.0006 0.0095
Brugia malayi beta-lactamase 0.0109 0.02 0.0693
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0028 0.0006 0.0051
Echinococcus granulosus tar DNA binding protein 0.0139 0.0273 0.0405
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0229 0.0488 0.5047
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.005 0.0058 0.02
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0028 0.0006 0.0017
Trypanosoma brucei cysteine peptidase C (CPC) 0.0428 0.0966 1
Loa Loa (eye worm) hypothetical protein 0.0071 0.0109 0.038
Plasmodium falciparum serine repeat antigen 2 0.0071 0.0109 0.2231
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.037 0.0827 0.2871
Toxoplasma gondii t-complex protein beta subunit 0.0027 0.0003 0.0027
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0056 0.0072 0.0248
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0052 0.0063 0.3019
Loa Loa (eye worm) oxidoreductase 0.0028 0.0006 0.0019
Brugia malayi RNA recognition motif domain containing protein 0.0139 0.0273 0.0944
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0117 0.0219 0.0219
Entamoeba histolytica cysteine proteinase, putative 0.0229 0.0488 0.4191
Loa Loa (eye worm) hypothetical protein 0.0031 0.0012 0.0042
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0067 0.0099 0.0146
Plasmodium vivax T-complex protein 1 subunit beta, putative 0.0027 0.0003 0.0054
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0052 0.0063 0.0357
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0027 0.0003 0.0004
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0218 0.0462 0.1605
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0071 0.0109 0.1126
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0071 0.0109 0.038
Brugia malayi Carboxylesterase family protein 0.0067 0.0099 0.0341
Schistosoma mansoni cathepsin F (C01 family) 0.0229 0.0488 0.0726
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0041 0.0037 0.0237
Brugia malayi Cathepsin L-like precursor 0.0229 0.0488 0.1693
Echinococcus multilocularis survival motor neuron protein 1 0.0956 0.2235 0.2235
Brugia malayi Patched family protein 0.0031 0.0012 0.004
Brugia malayi Importin beta-1 subunit 0.0031 0.0012 0.0038
Schistosoma mansoni tar DNA-binding protein 0.0139 0.0273 0.0405
Entamoeba histolytica cysteine proteinase, putative 0.0135 0.0263 0.2244
Onchocerca volvulus 0.0165 0.0335 0.2185
Entamoeba histolytica acyl-CoA synthetase, putative 0.0096 0.0168 0.1426
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0041 0.0036 0.0122
Brugia malayi MAP kinase sur-1 0.005 0.0058 0.02
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0229 0.0488 0.5047
Echinococcus granulosus acetylcholinesterase 0.0067 0.0099 0.0146
Brugia malayi beta-lactamase family protein 0.0109 0.02 0.0693
Loa Loa (eye worm) hypothetical protein 0.0031 0.0012 0.0042
Brugia malayi Patched family protein 0.0031 0.0012 0.004
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0081 0.0132 0.2685
Trypanosoma brucei T-complex protein 1, beta subunit, putative 0.0027 0.0003 0.0027
Brugia malayi Cathepsin L-like precursor 0.0229 0.0488 0.1693
Loa Loa (eye worm) hypothetical protein 0.0083 0.0138 0.0479
Trypanosoma cruzi PAB1-binding protein , putative 0.0083 0.0138 0.0477
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0109 0.02 0.0695
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0071 0.0109 0.1126
Loa Loa (eye worm) hypothetical protein 0.037 0.0827 0.2873
Echinococcus multilocularis chaperonin containing TCP1, subunit 2 (beta) 0.0027 0.0003 0.0003
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0071 0.0109 0.2231
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0071 0.0109 0.1126
Entamoeba histolytica cysteine protease, putative 0.0135 0.0263 0.2244
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0229 0.0488 0.5047
Loa Loa (eye worm) hypothetical protein 0.0028 0.0006 0.0019
Trichomonas vaginalis D-aminoacylase, putative 0.0109 0.02 0.2066
Echinococcus granulosus carboxylesterase 5A 0.0067 0.0099 0.0146
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0068 0.0101 0.0591
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0071 0.0109 0.1126
Schistosoma mansoni survival motor neuron protein 0.0195 0.0407 0.0604
Schistosoma mansoni cathepsin B (C01 family) 0.0071 0.0109 0.0162
Leishmania major acetyl-CoA synthetase, putative 0.0028 0.0006 0.0051
Giardia lamblia Kinase, CMGC MAPK 0.005 0.0058 0.0571
Plasmodium falciparum serine repeat antigen 8 0.0071 0.0109 0.2231
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0028 0.0006 0.0101
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0327 0.0725 0.2516
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0041 0.0036 0.0035
Echinococcus multilocularis cysteine protease 0.0229 0.0488 0.0488
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0071 0.0109 0.2231
Echinococcus multilocularis cathepsin L 0.0135 0.0263 0.0262
Giardia lamblia Encystation-specific protease 0.0071 0.0109 0.1101
Echinococcus granulosus geminin 0.0703 0.1627 0.2423
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0135 0.0263 0.2716
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.005 0.0058 0.02
Brugia malayi cathepsin Z-like cysteine proteinase 0.0071 0.0109 0.0378
Echinococcus granulosus cathepsin b 0.1225 0.2881 0.4289
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0072 0.011 0.065
Giardia lamblia Cathepsin B precursor 0.0071 0.0109 0.1101
Schistosoma mansoni gynecophoral canal protein 0.0097 0.0172 0.0254
Entamoeba histolytica cysteine protease, putative 0.0135 0.0263 0.2244
Toxoplasma gondii patched family protein 0.0031 0.0012 0.0118
Toxoplasma gondii cathepsin CPC2 0.0071 0.0109 0.1126
Trypanosoma brucei importin beta-1 subunit, putative 0.0031 0.0012 0.0114
Echinococcus granulosus tumor protein p63 0.0354 0.0788 0.1172
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0117 0.0219 0.0326
Echinococcus granulosus importin subunit beta 1 0.0031 0.0012 0.0016
Loa Loa (eye worm) beta-lactamase 0.0109 0.02 0.0695
Leishmania major cysteine peptidase A (CPA) 0.0229 0.0488 0.5047
Plasmodium vivax vivapain-2 0.0229 0.0488 1
Brugia malayi Patched family protein 0.0031 0.0012 0.004
Brugia malayi TAR-binding protein 0.0139 0.0273 0.0944
Echinococcus granulosus survival motor neuron protein 1 0.0956 0.2235 0.3328
Brugia malayi Bromodomain containing protein 0.0043 0.0041 0.0141
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0071 0.0109 0.1101
Onchocerca volvulus Lactoylglutathione lyase homolog 0.0097 0.0172 0.1118
Echinococcus granulosus snurportin 1 0.0327 0.0725 0.1079
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0229 0.0488 0.5047
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0071 0.0109 0.2231
Echinococcus multilocularis thyroid hormone receptor alpha 0.0041 0.0036 0.0035
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0037 0.0028 0.004
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0229 0.0488 0.0488
Brugia malayi Patched related family protein 10 0.0031 0.0012 0.004
Onchocerca volvulus 0.0031 0.0012 0.0075
Loa Loa (eye worm) hypothetical protein 0.0072 0.011 0.0382
Brugia malayi RNA binding protein 0.0139 0.0273 0.0944
Onchocerca volvulus Cathepsin L homolog 0.0229 0.0488 0.319
Trypanosoma cruzi cysteine peptidase, putative 0.0229 0.0488 0.1693
Onchocerca volvulus 0.0229 0.0488 0.319
Echinococcus multilocularis snurportin 1 0.0327 0.0725 0.0724
Schistosoma mansoni hypothetical protein 0.021 0.0444 0.066
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0125 0.0238 0.2457
Schistosoma mansoni hypothetical protein 0.0093 0.0162 0.024
Giardia lamblia Cathepsin B precursor 0.0428 0.0966 1
Echinococcus multilocularis cathepsin b 0.1225 0.2881 0.288
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.0093 0.0162 0.0558
Giardia lamblia Cysteine protease 0.0071 0.0109 0.1101
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0096 0.0168 0.121
Echinococcus granulosus Niemann Pick C1 protein 0.0509 0.116 0.1727
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0028 0.0006 0.0051
Loa Loa (eye worm) MBCTL1 0.0116 0.0216 0.0751
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0229 0.0488 0.5047
Plasmodium vivax unspecified product 0.0135 0.0263 0.538
Echinococcus multilocularis cathepsin b 0.1225 0.2881 0.288
Brugia malayi Cathepsin L-like precursor 0.0229 0.0488 0.1693
Brugia malayi Carboxylesterase family protein 0.0067 0.0099 0.0341
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0041 0.0036 0.0122
Giardia lamblia Cathepsin L-like protease 0.0071 0.0109 0.1101
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0428 0.0966 0.1438
Loa Loa (eye worm) hypothetical protein 0.0048 0.0053 0.0184
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0071 0.0109 0.1101
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0048 0.0053 0.0184
Toxoplasma gondii cathepsin CPL 0.0229 0.0488 0.5047
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0041 0.0036 0.0052
Toxoplasma gondii LsmAD domain-containing protein 0.0083 0.0138 0.1423
Echinococcus multilocularis lamin dm0 0.0056 0.0072 0.0071
Loa Loa (eye worm) hypothetical protein 0.0067 0.0099 0.0343
Mycobacterium ulcerans hypothetical protein 0.0097 0.0172 0.1235
Leishmania major cathepsin L-like protease 0.0229 0.0488 0.5047
Toxoplasma gondii patched family protein 0.0031 0.0012 0.0118
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0071 0.0109 0.2231
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0054 0.0068 0.0101
Loa Loa (eye worm) hypothetical protein 0.0041 0.0036 0.0124
Mycobacterium tuberculosis Probable hydrolase 0.0109 0.02 0.121
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0135 0.0263 0.2716
Loa Loa (eye worm) hypothetical protein 0.0067 0.0099 0.0343
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0229 0.0488 0.0488
Plasmodium vivax vivapain-3 0.0135 0.0263 0.538
Trichomonas vaginalis penicillin-binding protein, putative 0.0109 0.02 0.2066
Onchocerca volvulus 0.0067 0.0099 0.0642

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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